Journal articles: 'MicroPro'

1

Masson, Aurélien, and Olivier Monteuuis. "RUBBER TREE CLONAL PLANTATIONS: GRAFTED VS SELF-ROOTED PLANT MATERIAL." BOIS & FORETS DES TROPIQUES 332 (September 18, 2017): 57–68. http://dx.doi.org/10.19182/bft2017.332.a31333.

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The forest tree species Hevea brasiliensis is extensively planted in the humid tropics to meet the increasing demand for natural rubber. Huge quantities of planting stock are therefore needed. The seed option remains the easiest and cheapest way to establish plantations of rubber trees but those show a great variability for vigor and also for latex yield. The rationale of produ- cing clones for overcoming this variability was already obvious in the early 1910’s but due to the difficulties encountered at that time for rooting shoots, grafting was used as an alternative cloning method. The striking increase in yield noticed from the graft-derived clonal plantations warranted their large scale development. Eventually, the budded clones by virtue of their much higher and uniform produc- tivity supplanted the seedlings in most industrial plantations. However, grafting is also associated with drawbacks and for decades efforts aiming at mass producing selected rubber tree clones on their own roots by rooted cuttings have been pur- sued. However, this approach was pro- gressively abandoned due to disappoin- ting rooting results and, from the 70’s onwards, priority has been given to in vitro methods which were booming during this period. But despite 40 years of heavy investments, industrial H. brasiliensis clones could still not be mass micropro- pagated in vitro efficiently enough to meet the requirements of large scale produc- tion. The situation may change radically soon, however, due to the development of new nursery techniques adapted to the mass clonal production by rooted cuttings of any H. brasiliensis selected genotype. Efforts to improve the techniques as well as the establishment of new field trials are underway in order to determine if self-rooted rubber tree clones are more productive than grafted ones. This old issue is becoming of overriding impor- tance considering the increasing pres- sure on land availability reducing thereby the prospects for expanding rubber tree plantations.

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Dupouy, Cécile, Robert Frouin, Marc Tedetti, Morgane Maillard, Martine Rodier, Fabien Lombard, Lionel Guidi, et al. "Diazotrophic <i>Trichodesmium</i> impact on UV–Vis radiance and pigment composition in the western tropical South Pacific." Biogeosciences 15, no. 16 (August 30, 2018): 5249–69. http://dx.doi.org/10.5194/bg-15-5249-2018.

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Abstract. We assessed the influence of the marine diazotrophic cyanobacterium Trichodesmium on the bio-optical properties of western tropical South Pacific (WTSP) waters (18–22∘ S, 160∘ E–160∘ W) during the February–March 2015 OUTPACE cruise. We performed measurements of backscattering and absorption coefficients, irradiance, and radiance in the euphotic zone with a Satlantic MicroPro free-fall profiler and took Underwater Vision Profiler 5 (UPV5) pictures for counting the largest Trichodesmium spp. colonies. Pigment concentrations were determined by fluorimetry and high-performance liquid chromatography and picoplankton abundance by flow cytometry. Trichome concentration was estimated from pigment algorithms and validated by surface visual counts. The abundance of large colonies counted by the UVP5 (maximum 7093 colonies m−3) was well correlated to the trichome concentrations (maximum 2093 trichomes L−1) with an aggregation factor of 600. In the Melanesian archipelago, a maximum of 4715 trichomes L−1 was enumerated in pump samples (3.2 m) at 20∘ S, 167 30∘ E. High Trichodesmium abundance was always associated with absorption peaks of mycosporine-like amino acids (330, 360 nm) and high particulate backscattering, but not with high Chl a fluorescence or blue particulate absorption (440 nm). Along the west-to-east transect, Trichodesmium together with Prochlorococcus represented the major part of total chlorophyll concentration; the contribution of other groups were relatively small or negligible. The Trichodesmium contribution to total chlorophyll concentration was the highest in the Melanesian archipelago around New Caledonia and Vanuatu (60 %), progressively decreased to the vicinity of the islands of Fiji (30 %), and reached a minimum in the South Pacific Gyre where Prochlorococcus dominated chlorophyll concentration. The contribution of Trichodesmium to zeaxanthin was respectively 50, 40 and 20 % for these regions. During the OUTPACE cruise, the relationship between normalized water-leaving radiance (nLw) in the ultraviolet and visible and chlorophyll concentration was similar to that found during the BIOSOPE cruise in the eastern tropical Pacific. Principal component analysis (PCA) of OUTPACE data showed that nLw at 305, 325, 340, 380, 412 and 440 nm was strongly correlated to chlorophyll and zeaxanthin, while nLw at 490 and 565 nm exhibited lower correlations. These results, as well as differences in the PCA of BIOSOPE data, indicated that nLw variability in the greenish blue and yellowish green during OUTPACE was influenced by other variables associated with Trichodesmium presence, such as backscattering coefficient, phycoerythrin fluorescence and/or zeaxanthin absorption, suggesting that Trichodesmium detection should involve examination of nLw in this spectral domain.

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Li, Min, and Zhi Shen Wu. "Enhancement in Thermal Property of Phase Change Microcapsule with Modified Carbon Nanotube." Advanced Materials Research 856 (December 2013): 314–17. http://dx.doi.org/10.4028/www.scientific.net/amr.856.314.

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Carbon nanotubes grafted with stearyl alcohol (CNTs-SA) was used to enhance the thermal conductivities of the microcapsules. Differential Scanning Calorimeter (DSC) and thermogravimetry (TG) analysis method are employed to measure thermal properties of the prepared MicroPCM containing the grafted CNTs (MicroPCM/CNTs-SA). The results indicated the phase change temperature and latent heat of MicroPCM/CNTs-SA was 26.2°C and 47.7J/g. An increase in thermal conductivity, thermal stability of MicroPCM/CNTs-SA was observed. After 100 heating and cooling cycles, MicroPCM/CNTs-SA still had better durability and thermal stability.

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Ma, Jie, Yuan Sheng Yang, Xiu Chun Wang, Jing Zhang, Shuo Liu, and Xi Bin Yi. "Effect of Impulse Voltage on Microstructure and Corrosion Resistance of Microarc Oxidation Coatings on AZ80 Magnesium Alloy." Key Engineering Materials 575-576 (September 2013): 418–22. http://dx.doi.org/10.4028/www.scientific.net/kem.575-576.418.

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Microarc oxidation coating and microarc oxidation-fluorocarbon coating were prepared on the surface of AZ80 magnesium alloy profiles. The phase structure, surface morphology and corrosion resistance of the coatings were investigated using SEM, XRD, copper sulfate spot test and polarization curve test. The main phase compositions of the microarc oxidation coatings were MgO, Mg2SiO4, MgSiO3, MgF2 and MgAl2O4. With increasing pulse voltage, the oxidation coating became thicker and the microstructure of the coating surface became compact; therefore the coating corrosion resistance was improved. The oxidation coating with pulse voltage of microarc oxidation controlled between 300-438V obtained the best corrosion resistance. The corrosion current density of magnesium alloy reduced 1-3 orders of magnitude after microarc oxidation treatment with increasing pulse voltage, and the corrosion resistance of microarc oxidation-fluorocarbon coating is desirable.

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Liao, Ai-Ho, Jeng-Jong Hwang, Chen-Han Li, Wen-Fang Cheng, and Pai-Chi Li. "Noninvasive Tumor Imaging with High-Frequency Ultrasound and MicroPET in Small Animals." Ultrasonic Imaging 29, no. 4 (October 2007): 201–12. http://dx.doi.org/10.1177/016173460702900401.

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In this study, we used a micro-ultrasound (microUS) system that we developed in-house as an alternative method for tumor growth calipers. In addition, microUS was combined with small-animal positron-emission tomography (microPET) for tumor metastatic assessment. MicroUS provides anatomical information that can be used for tumor volume measurements while microPET is a functional imaging method with positron-emitting radiophamaceuticals, such as 18F-labeled deoxyglucose, [18F]FDG. In this study, microUS and microPET were performed in a mouse tumor longitudinal study (2–8 weeks), both with 3D tumor segmentation and volume measurements. Compared with vernier calipers, microPET generally overestimated tumor volumes during weeks 2–4 due to its inadequate spatial resolution. During weeks 5–8, standard deviations of microPET results were large due to tumor hypoxia or necrosis. On the contrary, microUS tumor volume measurements were more reliable as they were less affected by these factors. Nonetheless, microUS is not able to provide functional information similar to that provided by microPET. Therefore, microUS and microPET are complementary to each other as microUS has superior spatial resolution and microPET provides functional information, such as hypoxia or necrosis in the progression of the tumor. With image registration and fusion, the combination can be a valuable tool for cancer research.

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Kindler, Birgit, Elif Celik Ayik, Annett Hübner, Bettina Lommel, Jutta Steiner, and Vera Yakusheva. "Surface and thickness measurement in the Targetlab of GSI." EPJ Web of Conferences 229 (2020): 02002. http://dx.doi.org/10.1051/epjconf/202022902002.

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For characterization of targets and foils prepared at the target laboratory as well as for characterization of e.g. degrader or windows of internal customers, different analytical devices are available. Besides a lot of standard equipment, the target laboratory of GSI holds a 3D-measurement system (MicroProf®) equipped with optical sensors for measuring surface parameters as well as total thickness variations contact-free. In the paper the measuring principle including the possibilities and features of the MicroProf®-system are explained and some different applications are shown.

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Yu, Xiaokun, Jingde Luan, Wei Chen, and Jialu Tao. "Preparation and Performance of Microencapsulated Phase Change Material with Paraffin Core and SiO2 Shell for High Latent Heat and Low Heat Loss by Sol–Gel Method." Nano 15, no. 12 (November 25, 2020): 2050156. http://dx.doi.org/10.1142/s1793292020501568.

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Microencapsulated phase change materials (MicroPCM) were prepared via sol–gel method using paraffin as heat storage core and silica as inorganic shell. The morphology feature, chemical structure, thermal properties and thermal stability of MicroPCM were characterized by the field emission scanning electron microscope (FE-SEM), Fourier transform infrared spectroscopy (FTIR), the differential scanning calorimeter (DSC), simultaneous thermal analyzer (STA) and the thermal conductivity meter. The results indicated that MicroPCM were spherical in shape with the shell thickness in the range from 236[Formula: see text]nm to 303[Formula: see text]nm. The stirring speed and TEOS dosage were key factor on the latent heat and supercool effect of MicroPCM. The maximum latent heat of MicroPCM was 240.2[Formula: see text][Formula: see text] with the heat loss of only 0.2[Formula: see text][Formula: see text] in phase transformation when it was prepared at the stirring speed of 400[Formula: see text]r/min and TEOS dosage of 20[Formula: see text]ml. MicroPCM was a promising material for thermal energy storage (TES).

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8

Ma, Jie, Yuan Sheng Yang, Xiu Chun Wang, Jing Zhang, Shuo Liu, Li Kun Jiang, and Xi Bin Yi. "Microstructure and Corrosion Resistance of Microarc Oxidation Coatings on AZ31 Magnesium Alloy Extrusion Profiles." Advanced Materials Research 557-559 (July 2012): 1993–97. http://dx.doi.org/10.4028/www.scientific.net/amr.557-559.1993.

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Microarc oxidation coatings were prepared on the surface of AZ31 magnesium alloy profiles. Oxidation time of the coatings was between 5min-10min. The phase structure, surface morphology and corrosion resistance of the coatings were investigated using SEM, XRD, copper sulfate spot test and polarization curve test. The results indicate: the main phase compositions of the microarc oxidation coatings are MgO, Mg2SiO4 and MgSiO3; with increasing pulse voltage, the micropore diameter of the coating surface becomes larger, the micropore number reduces and the coating surface roughness increases; the corrosion current density of magnesium alloy reduces significantly after microarc oxidation treatment. The pulse voltage of microarc oxidation should be controlled between 240V-360V to obtain the best corrosion resistance.

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9

Peng, Guang Huai, Bao Jun Han, Ling Fang, Xue Feng Guo, and Xiao Lian Zhang. "Effect of Negative Pulse Voltage on the Microstructure and Corrosion Resistance of Microarc Oxidation Film of A356 Aluminum Alloy." Materials Science Forum 675-677 (February 2011): 1193–96. http://dx.doi.org/10.4028/www.scientific.net/msf.675-677.1193.

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The effect of negative pulse voltage on the microstructure and corrosion resistance of microarc oxidation film of A356 aluminum alloy treated by microarc technique was investigated by SEM, coating thickness gauge and electrochemical workstation etc. The results show the negative pulse voltage greatly influences the microstructure and corrosion resistance of microarc oxidation film by its electrode reaction. The film thickness increases while the size of pore and roughness of the film surface decreases initially and then increases with negative pulse voltage increasing. The microarc oxidation treatment considerably improved corrosion resistance, and the highest corrosion potential was -1.16V, which was 0.38V higher than that of substrate, and the corrosion current was lower than that of substrate about three orders of magnitude.

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10

Jagot, Ferdinand, and Nathalie Davoust. "Les microARN." médecine/sciences 33, no. 6–7 (June 2017): 620–28. http://dx.doi.org/10.1051/medsci/20173306019.

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11

Hartmann, Caroline, Fabienne Corre-Menguy, Adnane Boualem, Mariana Jovanovic, and Christine Lelandais-Brière. "Les microARN." médecine/sciences 20, no. 10 (October 2004): 894–98. http://dx.doi.org/10.1051/medsci/20042010894.

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12

Zharinov, A. V. "Vacuum microarc." Journal of Experimental and Theoretical Physics 98, no. 3 (March 2004): 496–502. http://dx.doi.org/10.1134/1.1705701.

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13

Lankenau, S., V. G. Corces, and D. H. Lankenau. "The Drosophila micropia retrotransposon encodes a testis-specific antisense RNA complementary to reverse transcriptase." Molecular and Cellular Biology 14, no. 3 (March 1994): 1764–75. http://dx.doi.org/10.1128/mcb.14.3.1764.

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The micropia transposable element of Drosophila hydei is a long terminal repeat-containing retrotransposon present in both the autosomes and the Y chromosome. micropia expression gives rise to a complex set of sense and antisense RNAs transcribed primarily during spermatogenesis. The most abundant sense RNAs constitute an assortment of heterogeneous high-molecular-weight transcripts expressed as constituents of the Y-chromosomal lampbrush loops of primary spermatocytes. In addition, micropia encodes a full-length RNA that extends between the two long terminal repeats of the element. The major 1.0-kb antisense RNA characterized is complementary to the reverse transcriptase and RNase H coding regions of micropia. It is expressed from a testis-specific promoter during the primary spermatocyte stages and is detectable until spermatid elongation stages. Sequence comparison of this promoter with the 5' region of other testis-specific genes allows the conception of a conserved sequence that is responsible for this pattern of expression. A 284-bp fragment containing this sequence is able to drive testis-specific expression of the Escherichia coli lacZ gene in Drosophila melanogaster. This sequence is conserved in the micropia elements present in other Drosophila species that also encode an antisense RNA. The evolutionary conservation of micropia antisense RNA expression and the sequences responsible for its testis-specific transcription suggests a role for this antisense RNA in the control of germ line expression of the full-length transcript or transposon-encoded proteins.

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14

Lankenau, S., V. G. Corces, and D. H. Lankenau. "The Drosophila micropia retrotransposon encodes a testis-specific antisense RNA complementary to reverse transcriptase." Molecular and Cellular Biology 14, no. 3 (March 1994): 1764–75. http://dx.doi.org/10.1128/mcb.14.3.1764-1775.1994.

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The micropia transposable element of Drosophila hydei is a long terminal repeat-containing retrotransposon present in both the autosomes and the Y chromosome. micropia expression gives rise to a complex set of sense and antisense RNAs transcribed primarily during spermatogenesis. The most abundant sense RNAs constitute an assortment of heterogeneous high-molecular-weight transcripts expressed as constituents of the Y-chromosomal lampbrush loops of primary spermatocytes. In addition, micropia encodes a full-length RNA that extends between the two long terminal repeats of the element. The major 1.0-kb antisense RNA characterized is complementary to the reverse transcriptase and RNase H coding regions of micropia. It is expressed from a testis-specific promoter during the primary spermatocyte stages and is detectable until spermatid elongation stages. Sequence comparison of this promoter with the 5' region of other testis-specific genes allows the conception of a conserved sequence that is responsible for this pattern of expression. A 284-bp fragment containing this sequence is able to drive testis-specific expression of the Escherichia coli lacZ gene in Drosophila melanogaster. This sequence is conserved in the micropia elements present in other Drosophila species that also encode an antisense RNA. The evolutionary conservation of micropia antisense RNA expression and the sequences responsible for its testis-specific transcription suggests a role for this antisense RNA in the control of germ line expression of the full-length transcript or transposon-encoded proteins.

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15

Chebodaeva, Valentina, Maria Sedelnikova, and Yurii Sharkeev. "Modification of Calcium Phosphate Microarc Coatings Surface by Boehmite Nanoparticles." Key Engineering Materials 743 (July 2017): 124–28. http://dx.doi.org/10.4028/www.scientific.net/kem.743.124.

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The surface modification of microarc calcium phosphate coatings by boehmite nanoparticles deposition was studied. The powder of aluminium nitride AlN was deposited on the microarc calcium phosphate coatings, and then the hydrolysis reaction was initiated. The boehmite (AlO(OH)) was formed as a result of the reaction. The influence of boehmite nanoparticles deposition on the properties of calcium phosphate microarc coatings (i.e. the morphology, elemental and phase composition, wettability) was studied. Experimental results show that the introduction of boehmite nanoparticles affects the surface morphology and wettability of the coating.

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Sancaktutar, Ahmet Ali, Senol Adanur, Tevfik Ziypak, Namık Kemal Hatipoglu, Mehmet Nuri Bodakcı, Haluk Soylemez, and İsa Ozbey. "Micropercutaneous Nephrolithotomy in the Management of Bilateral Renal Stones in a 7-Month-Old Infant: The Youngest Case in the Literature." Urologia Internationalis 96, no. 2 (August 14, 2014): 238–40. http://dx.doi.org/10.1159/000360645.

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During infancy, the renal parenchyma and pelvicalyceal system are relatively fragile. Therefore, percutaneous nephrolithotomy for the management of renal stones in this age group is a challenging procedure for urologists. Herein, we present the uneventful management of bilateral renal stones using micropercutaneous nephrolithotomy (microperc) administered to a 7-month-old infant with recurrent urinary tract infections. In this paper, the advantages and disadvantages of the microperc procedure are discussed. As far as we know, our patient is the youngest case in whom the microperc procedure has been performed.

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Nedergaard, Mette Kjoelhede, Signe Regner Michaelsen, Thomas Urup, Helle Broholm, Henrik El Ali, Hans Skovgaard Poulsen, Marie-Thérése Stockhausen, Andreas Kjaer, and Ulrik Lassen. "18F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma." PLOS ONE 10, no. 2 (February 13, 2015): e0115315. http://dx.doi.org/10.1371/journal.pone.0115315.

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Kim, Joon-Wan, Kazuhiro Yoshida, Toru Ide, and Shinichi Yokota. "Fabrication, Experiment, and Simulation of a Flexible Microvalve-Integrated Microarm for Microgrippers Using Electrorheological Fluid." Journal of Robotics and Mechatronics 32, no. 2 (April 20, 2020): 333–43. http://dx.doi.org/10.20965/jrm.2020.p0333.

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Because of the power density advantages of fluid power systems, many researchers have developed microactuators using homogeneous electrorheological (ER) fluids (ERFs) for applications to various micromachines. An ER valve, as a critical component of the ER actuator, can control ERF flow by the apparent viscosity increase resulting from the applied electric field without any mechanical moving parts. Hence, it is adequate for the miniaturization of a fluidic microactuator. However, it is not easy to integrate rigid ER valves into soft microrobots. To overcome these limitations, we developed a novel elastic ER microarm using flexible ER valves (FERVs) in this study. Each microarm consists of an FERV, a movable chamber, and a displacement constraint element, so that it bends with the inner pressure controlled by the FERV. We proposed and developed a micro-electromechanical system fabrication process for the FERV, movable chamber, and displacement constraint element. By utilizing the proposed method, we successfully fabricate a FERV-integrated microarm. The characteristics of the FERV were experimentally clarified. In addition, the bending motion of the FERV-integrated microarm was demonstrated by experiments and verified by finite-element method simulation. This ER microarm was shown to be feasible for an ER microgripper composed of multiple microarms.

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Kubasová, Nikola, Silvia Zichová, Adriána Brisudová, and Svetlana Hrouzková. "Sample matrix influence on microdrop hold-up in single drop microextraction." Acta Chimica Slovaca 13, no. 1 (April 1, 2020): 19–25. http://dx.doi.org/10.2478/acs-2020-0004.

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AbstractSingle drop microextraction has become a widespread liquid/liquid microextraction technique owing to its simplicity, high preconcentration factor and low consumption of organic solvents in the extraction due to direct introduction of the very low volume of extract into the analytical system. Crucial features ensuring excellent repeatability of single drop microextraction include: solvent volume, solvent type, sample agitation, salts addition, and pH. The influence of sample quality on the microdrop volume and agitation type was studied. Effect of the sample matrix, such as water, acid content samples (orange juice), sample containing alcohol (plum brandy) and protein content sample (milk), on the microdrop hold-up was also investigated. For water analysis, several organic solvents such as chloroform, dichloromethane, tetrachloromethane, tetrachloroethane and chlorobenzene were tested; last three mentioned were suitable for SDME experiments. For milk samples analysis, chlorobenzene microdrop was found to be optimal; advantage of salt addition has been reported. For orange samples, 1:10 dilution was suggested with stable microdrop volumes (toluene) of up to 6 µL for lower stirring rates (100 rpm and 250 rpm). For alcohol-content samples, the change of alcohol percentage of real-life samples had to be considered. A strong influence of the matrix quality on the microdrop stability has been proven.

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Pi, Yan Hui, Chun Zhang, Ke Xi Liao, and Ou Yang Sun. "Microcor Corrosion Monitoring Technology and its Applications." Applied Mechanics and Materials 318 (May 2013): 579–83. http://dx.doi.org/10.4028/www.scientific.net/amm.318.579.

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With the purpose of comprehensive understanding of the oil and gas pipeline corrosion factors and formulating correct anti-corrosion programs, working principle, technical characteristic, monitoring procedures, application examples of Microcor corrosion monitoring were described in this paper. Compared with commonly used corrosion monitoring technology such as weight loss method, linear polarization resistance method, resistance probe method, Microcor corrosion monitoring has the advantages of high sensitivity, wide application, stable performance, fast response and high resolution. Microcor corrosion monitoring corrosion is the ideal test technology of corrosion process monitoring and corrosion process control, especially for the inhibitor effect evaluation.

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Garrido, Victoria, María Collantes, Montserrat Barberán, Iván Peñuelas, Javier Arbizu, Beatriz Amorena, and María-Jesús Grilló. "In VivoMonitoring of Staphylococcus aureus Biofilm Infections and Antimicrobial Therapy by [18F]Fluoro-Deoxyglucose–MicroPET in a Mouse Model." Antimicrobial Agents and Chemotherapy 58, no. 11 (August 25, 2014): 6660–67. http://dx.doi.org/10.1128/aac.03138-14.

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ABSTRACTA mouse model was developed forin vivomonitoring of infection and the effect of antimicrobial treatment againstStaphylococcus aureusbiofilms, using the [18F]fluoro-deoxyglucose–MicroPET ([18F]FDG-MicroPET) image technique. In the model, sealed Vialon catheters were briefly precolonized withS. aureusstrains ATCC 15981 or V329, which differ in cytotoxic properties and biofilm matrix composition. After subcutaneous implantation of catheters in mice, theS. aureusstrain differences found in bacterial counts and the inflammatory reaction triggered were detected by the regular bacteriological and histological procedures and also by [18F]FDG-MicroPET image signal intensity determinations in the infection area and regional lymph node. Moreover, [18F]FDG-MicroPET imaging allowed the monitoring of the rifampin treatment effect, identifying the periods of controlled infection and those of reactivated infection due to the appearance of bacteria naturally resistant to rifampin. Overall, the mouse model developed may be useful for noninvasivein vivodeterminations in studies onS. aureusbiofilm infections and assessment of new therapeutic approaches.

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Deng, Haishun, Shiju He, Feiyu Mao, and Chuanli Wang. "Effects of Micropit Depths on Tribology Performance of Textured Port Plate Pair." Advances in Materials Science and Engineering 2018 (November 11, 2018): 1–7. http://dx.doi.org/10.1155/2018/9501708.

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In order to improve the friction and wear performance of textured port plate pair, effects of the micropit depth on the tribology performance is studied in the paper. The relation between the micropit depth and the port plate pair’s oil loading carrying capacity is analyzed in theory; with the friction coefficient, the wear volume and the surface roughness as the evaluation criteria, effects of the micropits’ depth on the tribology performance are investigated. The conclusions are shown as follows: oil loading capacity would come to its peak when the oil film thickness is equal to the micropit depth; the optimal micropit depth is unrelated to the area ratios and micropits’ diameters. With the same parameters, the effects of antifriction is optimal when the micropits’ depth is 10 μm, while antiwear and surface integrity are optimal when 15 μm. When the micropits’ depth is 5 μm, the antiwear, surface roughness, and antifriction are worse compared with those of the untextured port plate pair.

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Zavaleta, C. L., W. T. Phillips, Y. C. Bradley, L. M. McMANUS, P. A. Jerabek, and B. A. Goins. "Characterization of an intraperitoneal ovarian cancer xenograft model in nude rats using noninvasive microPET imaging." International Journal of Gynecologic Cancer 17, no. 2 (2007): 407–17. http://dx.doi.org/10.1111/j.1525-1438.2007.00814.x.

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MicroPET is a noninvasive imaging modality that can potentially track tumor development in nude rats using the radiotracer fluorine 18-fluorodeoxyglucose (18F-FDG). Our goal was to determine whether microPET, as opposed to more invasive techniques, could be used to noninvasively monitor the development of ovarian cancer in the peritoneal cavity of nude rats for monitoring treatment response in future studies. Female nude rats were inoculated intraperitoneally with 36 million NIH:OVCAR-3 cells. Imaging was carried out at 2, 4, 6, or 8 weeks postinoculation. Each rat was fasted overnight and intravenously injected with 11.1 MBq (300 μCi) of 18F-FDG in 0.2 mL of saline. Thirty minutes following injection, the rats were placed in the microPET and scanned for 30 min. After imaging, rats were euthanized for ascites and tissue collection for biodistribution and histopathologic correlation. Standard uptake values (SUVs) of 18F-FDG within the peritoneal cavity were also calculated from regions of interest analysis of the microPET images. MicroPET images showed diffuse increased uptake of 18F-FDG throughout the peritoneal cavity of tumor rats (mean SUV = 4.64) compared with control rats (mean SUV = 1.03). Ascites gathered from tumor-bearing rats had increased 18F-FDG uptake as opposed to the peritoneal fluid collected from control rats. Biodistribution data revealed that the percent injected dose per gram (% ID/g) was significantly higher in tumor-bearing rats (6.29%) than in control rats (0.59%) in the peritoneal lymph nodes. Pathology verified that these lymph nodes were more reactive in tumor-bearing rats. By 6 weeks, some rats developed solid masses within the peritoneum, which could be detected on microPET images and confirmed as tumor by histopathology. 18F-FDG uptake in these tumors at necropsy was 2.83% ID/g. These results correlate with previous invasive laparoscopic studies of the same tumor model and demonstrate that microPET using 18F-FDG is a promising noninvasive tool to localize and follow tumor growth in an intraperitoneal ovarian cancer model.

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Moore, Amy H., Cheri L. Osteen, Arion F. Chatziioannou, David A. Hovda, and Simon R. Cherry. "Quantitative Assessment of Longitudinal Metabolic Changes In Vivo after Traumatic Brain Injury in the Adult Rat using FDG-MicroPET." Journal of Cerebral Blood Flow & Metabolism 20, no. 10 (October 2000): 1492–501. http://dx.doi.org/10.1097/00004647-200010000-00011.

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With the advent and emerging importance of neurobiology and its relation to behavior, scientists desire the capability to apply noninvasive, quantitative imaging of neuronal activity to small rodents. To this end, the authors' laboratory has developed microPET, a high-resolution positron emission tomography (PET) scanner that is capable of performing in vivo molecular imaging at a resolution sufficient to resolve major structures in the rat brain. The authors report in this article that, in conjunction with 2-[18F]fluoro-2-deoxyglucose (FDG), microPET provides accurate rates of cerebral glucose metabolism (59.7 to 108.5 μmol/100 g·min) in conscious adult rats as validated by within-subject autoradiographic measurements (59.5 to 136.2 μmol/100 g·min; r = 0.88; F[1,46] = 168.0; P < 0.001). By conducting repeated quantitative scanning, the authors demonstrate the sensitivity and accuracy of FDG-microPET to detect within-subject metabolic changes induced by traumatic brain injury. In addition, the authors report that longitudinal recovery from traumatic brain injury-induced metabolic depression, as measured by quantitative FDG-microPET, is significantly correlated ( r = 0.65; P < 0.05) to recovery of behavioral dysfunction, as assessed by the Morris Water Maze performance of the same rats, after injury. This is the first study to demonstrate that FDG-microPET is quantitative, reproducible, and sensitive to metabolic changes, introducing a new approach to the longitudinal study of small animal models in neuroscience research.

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Lee, Hye Jeong, Mohammed N. Tantawy, Ki Taek Nam, Inyeong Choi, Todd E. Peterson, and Ronald R. Price. "Evaluation of an Intraperitoneal Ovarian Cancer Syngeneic Mouse Model Using18F-FDG MicroPET Imaging." International Journal of Gynecologic Cancer 21, no. 1 (2011): 22–27. http://dx.doi.org/10.1097/igc.0b013e3182021bda.

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Objectives:The objective of this study was to evaluate the syngeneic immunocompetent mouse model by using the micro-positron emission tomography with 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (18F-FDG microPET) imaging of ovarian tumor growth.Methods:ID8 ovarian carcinoma cells derived from C57BL/6 mice were intraperitoneally injected into female C57BL/6 mice. Mice were injected with18F-FDG (7.4 MBq, intravenous injection), and microPET images were obtained 40 minutes later. Micro-computed tomographic images were also obtained immediately after microPET images for anatomical reference.18F-FDG microPET images were acquired at baseline and at 4, 8, 10, and 11 weeks after tumor cell injection. The maximum standardized uptake value (SUVmax) in each time point was obtained from the images and compared to follow the tumor growth.Results:Physiological uptake of18F-FDG was intensely found in the bladder and heart and frequently in the gastrointestinal tract. Diffused uptake of18F-FDG was observed in the peritoneal cavity of all tumor-bearing mice at 4 weeks, and high focal uptakes were developed in the peritoneal cavity at 8 to 11 weeks. High focal uptakes increased over time, correlating with a progressive increase in the SUVmaxof18F-FDG. At 11 weeks, the SUVmaxvalue was significantly increased (1.49 ± 0.10 at 11 weeks vs 0.29 ± 0.03 at baseline,P< 0.01). Tumors in the gut and peritoneum were confirmed by anatomical and histopathological examination.Conclusions:Our results demonstrate that the peritoneal tumor growth in the syngeneic ovarian cancer model can be detected by the18F-FDG microPET imaging.

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Lu, Chuang, Fa Qin Xie, and Li Ping Zhu. "Microstructure and Tribological Properties of Microarc Oxidation Coatings on Al-Si Alloy." Key Engineering Materials 703 (August 2016): 112–18. http://dx.doi.org/10.4028/www.scientific.net/kem.703.112.

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Microarc oxidation(MAO) was used to prepare the coatings on the surface of Al-Si alloy. Besides, scanning electron microscope (SEM), energy dispersive spectrometer (EDS) and X-ray diffraction (XRD) were utilized to research the microstructure characteristics, the components distribution, and the phase compositions, for the microarc oxidation coatings on Al-Si alloys. Furthermore, the growth process and wear properties of the coatings were explored. Results indicated that:the phase compositions of microarc oxidized coating consisted of mullite (3Al2O3·2SiO2), α- Al2O3 and γ- Al2O3. With the increase of load, the friction coefficient of the coating decreased, however it was greater than that of Al-Si alloy substrate. The wear resistance of the coating were one time higher than that of the substrate.

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Tanaka, Shigeru, Yukari Ishikawa, Naoki Ohashi, Junichi Niitsuma, Takashi Sekiguchi, and Noriyoshi Shibata. "Near-Infrared Light Emission from of Er-Doped ZnO Thin Film in Micropits Processed on Si Substrate." Key Engineering Materials 320 (September 2006): 113–16. http://dx.doi.org/10.4028/www.scientific.net/kem.320.113.

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We have obtained Er-doped ZnO thin film in a micropattern of reverse trapezoids processed on Si substrate by sputtering and ultrafine polishing techniques. Near-infrared light emission was detected successfully from the thin film filling a single micropit with 10 μm square. Transmission electron microscopy (TEM) observation showed epitaxial growth of ZnO crystals along the curvature of the micropit.

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Baudry, Anne, Sophie Mouillet-Richard, Benoît Schneider, Jean-Marie Launay, and Odile Kellermann. "Le microARN-16." médecine/sciences 27, no. 2 (February 2011): 128–31. http://dx.doi.org/10.1051/medsci/2011272128.

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Hinault, Charlotte, Olivier Dumortier, and Emmanuel Van Obberghen. "MicroARN et diabète." médecine/sciences 29, no. 8-9 (August 2013): 785–90. http://dx.doi.org/10.1051/medsci/2013298019.

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Schäfer, J., J. P. Mondia, R. Sharma, Z. H. Lu, and L. J. Wang. "Modular microdrop generator." Review of Scientific Instruments 78, no. 6 (June 2007): 066102. http://dx.doi.org/10.1063/1.2742809.

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Zeichick, Alan. "Yahsoft or Microhoo?" netWorker 12, no. 1 (March 2008): 5–8. http://dx.doi.org/10.1145/1346942.1346944.

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Malyshev, V. N., A. M. Volkhin, and B. M. Gantimirov. "Tribological Characteristics Improvement of Wear Resistant MAO-Coatings." Journal of Coatings 2013 (June 19, 2013): 1–5. http://dx.doi.org/10.1155/2013/262310.

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Currently, the most promising technology of coating formation is microarc oxidation (MAO) with unique properties of the surface layer, which combine high wear resistance, corrosion resistance, and heat and erosion resistance. Microarc oxidation can be used for parts and components manufacturing in various segments of industries. However, the technology improvement by improving the tribological characteristics of MAO-coatings can not only enhance economic effect, but also expand its application.

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Lee, Wan-Chi, Chih-Hsien Chang, Chung-Li Ho, Liang-Cheng Chen, Yu-Hsien Wu, Jenn-Tzong Chen, Ying-Ling Wang, and Te-Wei Lee. "Early Detection of Tumor Response by FLT/MicroPET Imaging in a C26 Murine Colon Carcinoma Solid Tumor Animal Model." Journal of Biomedicine and Biotechnology 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/535902.

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Fluorine-18 fluorodeoxyglucose (-FDG) positron emission tomography (PET) imaging demonstrated the change of glucose consumption of tumor cells, but problems with specificity and difficulties in early detection of tumor response to chemotherapy have led to the development of new PET tracers. Fluorine-18-fluorothymidine (-FLT) images cellular proliferation by entering the salvage pathway of DNA synthesis. In this study, we evaluate the early response of colon carcinoma to the chemotherapeutic drug, lipo-Dox, in C26 murine colorectal carcinoma-bearing mice by -FDG and -FLT. The male BALB/c mice were bilaterally inoculated with and C26 tumor cells per flank. Mice were intravenously treated with 10 mg/kg lipo-Dox at day 8 after -FDG and -FLT imaging. The biodistribution of -FDG and -FLT were followed by the microPET imaging at day 9. For the quantitative measurement of microPET imaging at day 9, -FLT was superior to -FDG for early detection of tumor response to Lipo-DOX at various tumor sizes (). The data of biodistribution showed similar results with those from the quantification of SUV (standard uptake value) by microPET imaging. The study indicates that -FLT/microPET is a useful imaging modality for early detection of chemotherapy in the colorectal mouse model.

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WANG, Y. M., B. L. JIANG, L. X. GUO, and T. Q. LEI. "ANTIFRICTION PROPERTY OF MICROARC OXIDATION COATING ON TITANIUM ALLOY UNDER SOLID LUBRICATING SLIDING CONDITION." Surface Review and Letters 11, no. 04n05 (August 2004): 367–72. http://dx.doi.org/10.1142/s0218625x04006360.

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Ceramic coatings were fabricated on Ti6Al4V alloy surface by microarc oxidation (MAO) in Na 2 SiO 3–( NaPO 3)6– NaAlO 2 solution using an AC power supply. Microstructure and phase composition of coating were characterized by SEM and XRD, respectively. The antifriction property of the coating with and without solid lubricant sliding against SAE 52100 steel ball was investigated on a pin-on-disk friction and wear tester. The results show that the microarc oxidation coating is relatively dense and uniform, mainly composed of rutile and anatase. The coating sliding against the steel has friction coefficient as low as 0.2–0.3 at an applied load of 0.5 N and sliding cycle below 2500, which is much smaller than that of uncoated Ti6Al4V against the same counterpart. The transferring of materials from the softer steel ball onto the coating surface is the main wear event, while the microarc oxidation coating is characterized by slight abrasive wear and adhesive wear. Introducing solid graphite lubricant into the porous surface of microarc oxidation coating significantly improves the long-term antifriction property (registering friction efficient of 0.15 in the long-term sliding) under a similar sliding condition. This improvement is attributed to the reduction of materials that are transferred from the softer steel ball onto the coating surface.

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Đukić Stojčić, Mirjana, Siniša Bjedov, Dragan Žikić, Lidija Perić, and Niko Milošević. "Effect of straw size and microbial amendment of litter on certain litter quality parameters, ammonia emission, and footpad dermatitis in broilers." Archives Animal Breeding 59, no. 1 (March 8, 2016): 131–37. http://dx.doi.org/10.5194/aab-59-131-2016.

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Abstract. This study was conducted to evaluate the impact of litter amendment (microbiological product – Micropan complex) and straw size (unchopped and chopped straw) on pH, moisture level, ammonia emission, and footpad dermatitis in broilers. A total of 1200 1-day-old Ross 308 broilers were randomly allocated to four treatments (2 × 2 factorial arrangement), with four replicates per treatment. Each replicate consisted of 75 as-hatched birds per pen. The first factor consisted of wheat straw – chopped (C) or unchopped (U) – and the second factor was the litter amendment with (WM) or without (OM) Micropan® (enzymatic bacterial product – Eurovix, USA). At 4, 5, and 6 weeks of the trial, the levels of ammonia concentration, moisture content, and pH of litter in each pen were measured. The foot pad lesions were evaluated at 21, 35, and 42 days of age. Broilers reared on chopped straw had significantly better leg condition as expressed by a smaller incidence and severity of footpad dermatitis. The pH value of litter was decreased and footpad quality was significantly improved by Micropan application in broilers kept on chopped and unchopped straw in the sixth week of age. There was no significant effect of Micropan application and straw size on ammonia emission in broiler housing.

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Liu, Wan Hui, Ai Lian Bao, Xin Yu Mao, and Guang Hai Zheng. "Microstructure and Properties of Microarc Oxidation Ceramic Coatings on Aluminum Alloy." Key Engineering Materials 353-358 (September 2007): 1895–98. http://dx.doi.org/10.4028/www.scientific.net/kem.353-358.1895.

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The paper discusses structure and property aspects of oxide films formed on 7075 aluminum alloys by microarc oxidation in alkali-silicate electrolytic solution. Microstructure, surface morphology and phase composition of the ceramic coatings were investigated by SEM and XRD. Distribution of hardness along the coating thickness was determined by microhardness analyses. The friction and wear behavior of the oxide films against steel counterparts was evaluated with a friction and wear tester. The results showed that the microarc oxidation coatings composed mainly of α-Al2O3 and γ-Al2O3 phase are dense and uniform, which indicates that the wear resistance of Al alloy could be improved obviously by microarc oxidation. The films possess a beneficial combination of 25~45 μm thickness, HV0.11500 microhardness and provide a low wear rate but a relatively high friction coefficient against GCr15 steel under dry friction condition.

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TANG, MING QI, WEI PING LI, HUI CONG LIU, and LI QUN ZHU. "THE EFFECT OF TITANIA SOL IN PHOSPHATE ELECTROLYTE ON MICROARC OXIDATION COATINGS ON ALUMINUM ALLOY." International Journal of Modern Physics B 24, no. 15n16 (June 30, 2010): 3190–95. http://dx.doi.org/10.1142/s0217979210066306.

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Black and gray microarc oxidation coatings have been obtained on 2A70 Aluminum alloy in phosphate electrolyte with and without titania sol, respectively. The growth process of the microarc oxidation coating in the electrolyte with titania sol was investigated. The coating was characterized by scanning electron microscopy (SEM), energy dispersive spectrometry (EDS) and X-ray. The coating thickness was measured by eddy current thickness meter. The results show that the titania sol increase the growth rate of microarc oxidation coating. In both cases the composition of coatings contain Al and O , and are mainly composed of γ- Al 2 O 3 and AlPO 4. Compared with the gray coating, large amount of Ti is found on the surface of black coating. The titania sol added in the electrolyte results in Ti in the coating, in the form of TiO and Al 2 TiO 5.

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Silva, Grasiele Teixeira da, Anderli Divina Ferreira Rios, Rafael Matias da Silva, Wilian Henrique Diniz Buso, Denise Rodrigues Conceição, and Rafaela Santos de Oliveira. "Biofertilizer in the control of the nematode Pratylenchus brachyurus in sugarcane crop." Scientia Agraria Paranaensis 19, no. 3 (November 3, 2020): 258–63. http://dx.doi.org/10.18188/sap.v19i3.23987.

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Biofertilizers can also be used as plague and disease control agents. The commercial product Microgeo® is a biological biofertilizer rich in microorganisms. Few studies have been carried out to evaluate the interaction between biofertilizer and nematodes. The objective of this study was to evaluate the efficiency of the Microgeo® biological fertilizer to control the nematode Pratylenchus brachyurus in two sugarcane cultivars. The work was carried out in greenhouse conditions with a completely randomized experimental design (DIC), in a triple factorial scheme (2 x 2 x 4), being two types of sugar cane (CTC 04 and CTC 9003), two types of management of the biofertilizer (Management 1: application of the biofertilizer and inoculation of the nematode at 0 days after transplanting (DAT), management 2: application of the biofertilizer and inoculation of the nematode in the roots of the plant 30 days later) and four doses of the liquid biofertilizer Microgeo® (0 L ha‑1; 150 L ha-1; 300 L ha-1; 450 L ha-1), with four replications. 800 specimens of P. brachyurus were inoculated in each experimental plot. The results showed that cultivating CTC 9003 during the conduct of the experiment showed greater susceptibility to the nematode compared to cultivating CTC 04. The biofertilizer Microgeo® showed no curative or preventive effect on the control of the nematode under the conditions of the experiment.

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Tong, Xin, Song Yu, and Lihui Wang. "Establishment of micropit diameter prediction models based on the support vector machine optimization." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 234, no. 12 (February 11, 2020): 2417–31. http://dx.doi.org/10.1177/0954406220906426.

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Many studies on microtextures have focused on the effect of laser processing parameters on microtextured morphology from the experimental point of view, and not on its influence on the physical field and stress field around the microtextures. This has resulted in the lack of accurate predictions on micropit diameters, thus reducing the processing efficiency. In order to address these problems, the effects of laser processing parameters on the precision machining, physical field, and stress field of micropit textures for a ball-end milling cutter were studied by experiments and simulation. The optimum laser processing parameters include laser power of 70%, scanning speed of 1700 mm/s, and scanning of seven times. Based on the optimized data of a support vector machine, the prediction models of micropit diameters for laser machining were established. The errors of the models are less than 10%, thus verifying their accuracy. This study can serve as a theoretical reference for the efficient processing of titanium alloys.

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Zhu, Zhijing, Chuanyun Yi, Tielin Shi, Yichun Zhang, Yang Gao, and Guanglan Liao. "Hot Embossing of Zr-Based Bulk Metallic Glass Micropart Using Stacked Silicon Dies." Advances in Materials Science and Engineering 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/179714.

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We demonstrated hot embossing of Zr65Cu17.5Ni10Al7.5bulk metallic glass micropart using stacked silicon dies. Finite element simulation was carried out, suggesting that it could reduce the stress below 400 MPa in the silicon dies and enhance the durability of the brittle silicon dies when using varying load mode (100 N for 60 s and then 400 N for 60 s) compared with using constant load mode (200 N for 120 s). A micropart with good appearance was fabricated under the varying load, and no silicon die failure was observed, in agreement with the simulation. The amorphous state of the micropart was confirmed by differential scanning calorimeter and X-ray diffraction, and the nanohardness and Young’s modulus were validated close to those of the as-cast BMG rods by nanoindentation tests. The results proved that it was feasible to adopt the varying load mode to fabricate three-dimensional Zr-based bulk metallic glass microparts by hot embossing process.

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Trivelin, P. C. O., W. A. R. Lara Cabezas, R. L. Victoria, and K. Reichardt. "Evaluation of a 15N plot design for estimating plant recovery of fertilizer nitrogen applied to sugar cane." Scientia Agricola 51, no. 2 (August 1994): 226–34. http://dx.doi.org/10.1590/s0103-90161994000200005.

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Two experiments were conducted on commercial sugar cane fields cropped with the variety SP70-1143, with the objective of evaluating a single row microplot design to determine plant recovery of 15N fertilizer nitrogen. One of them used 15N-aqua ammonia and 15N-urea applied to two linear meter microplots of a ratoon crop (four replicates). The second used one linear meter microplots (three replicates) which received 15N-aqua ammonia only. The fertilizers were applied on 15cm deep furrows, located 25cm from both sides of the cane row. One linear meter of ratoon cane, inside and outside of the microplot, and on the same and adjacent rows were harvested twelve months after fertilization. The results indicate the feasibility of using single row segments of ratoon cane with 15N-fertilizer. The main advantage of this microplot design, when compared to the classical 3 contiguous row segments, is that only one third of the labeled fertilizer is needed. In a single row, in order to separate the nitrogen taken up by plants from the fertilizer applied to the row (Nr dff r), from that applied to adjacent rows (Nr dff r+1, and Nr dff r-1), the following should be considered: (a) a border segment of 0.5 to 1.0m inside the plot, so that Ndff results from plants harvested in the center of the microplot represent the actual value of fertilizer nitrogen taken up from that applied to the same row, and (b) harvest of plants from adjacent rows at equivalent positions to those sampled inside the microplot, to quantify the 15N-fertilizer uptake by outside plants (Nr+1dff r and Nr-1dff r), which is assumed to be the same as non labeled fertilizer applied to adjacent rows (Nr dff r+l and Nr dff r-1) taken up by inside plants. The Ndff total values should be calculated by the equation: Ndff total = Nr dff r + Nr+1dff r + Nr-1dff r.

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42

Amrouche, Lucile, Raja Bonifay, and Dany Anglicheau. "MicroARN et maladies rénales." médecine/sciences 27, no. 4 (April 2011): 398–404. http://dx.doi.org/10.1051/medsci/2011274016.

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Desai, Mahesh, and Shashikant Mishra. "‘Microperc’ micro percutaneous nephrolithotomy." Current Opinion in Urology 22, no. 2 (March 2012): 134–38. http://dx.doi.org/10.1097/mou.0b013e32834fc3bb.

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Schäfer, J., J. P. Mondia, R. Sharma, Z. H. Lu, A. S. Susha, A. L. Rogach, and L. J. Wang. "Quantum Dot Microdrop Laser." Nano Letters 8, no. 6 (June 2008): 1709–12. http://dx.doi.org/10.1021/nl080661a.

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Ogier-Denis, Eric, Magali Fasseu, Alain Vandewalle, and Marc Laburthe. "MicroARN et physiopathologie intestinale." médecine/sciences 23, no. 5 (May 2007): 509–14. http://dx.doi.org/10.1051/medsci/2007235509.

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Banpurkar, Arun G., Kevin P. Nichols, and Frieder Mugele. "Electrowetting-Based Microdrop Tensiometer." Langmuir 24, no. 19 (October 7, 2008): 10549–51. http://dx.doi.org/10.1021/la801549p.

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Goertzen, A. L., P. Rosa-Neto, M. L. Camborde, S. McCormick, and C. J. Thompson. "Accelerated microPET Transmission Imaging." IEEE Transactions on Nuclear Science 55, no. 5 (October 2008): 2501–7. http://dx.doi.org/10.1109/tns.2008.2000859.

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Hynes, N. "Owusu-Ankomah Microcron Begins." Nka Journal of Contemporary African Art 2015, no. 36 (January 1, 2015): 112–15. http://dx.doi.org/10.1215/10757163-2914383.

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Nagy, Andras, Marina Gertsenstein, Kristina Vintersten, and Richard Behringer. "Setting Up Microdrop Cultures." Cold Spring Harbor Protocols 2006, no. 1 (January 1, 2006): pdb.prot4353. http://dx.doi.org/10.1101/pdb.prot4353.

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Bardin, Pauline, Florence Sonneville, and Olivier Tabary. "Mucoviscidose : dans la ligne des miR." médecine/sciences 34, no. 6-7 (June 2018): 554–62. http://dx.doi.org/10.1051/medsci/20183406015.

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La mucoviscidose est la plus fréquente des maladies génétiques dans les populations d’origine caucasienne, caractérisée par des mutations du gène codant le canal chlorure CFTR. Bien que ce gène soit connu depuis 1989, les solutions thérapeutiques curatives proposées aux patients restent limitées. De nouvelles stratégies thérapeutiques sont explorées, comme celles ciblant les microARN qui participent à la régulation de l’expression d’ARN messagers cibles. Cette revue fait le point sur les travaux portant sur l’implication de ces microARN dans la mucoviscidose, notamment dans le contrôle des canaux ioniques, de l’inflammation, de l’infection et de l’obstruction bronchique, et leurs potentiels thérapeutiques.

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Journal articles on the topic 'MicroPro'

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