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Relevant bibliographies by topics / Microvesicle particles MVP

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Academic literature on the topic 'Microvesicle particles MVP'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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Journal articles on the topic "Microvesicle particles MVP"

1

Chauhan, Shreepa J., Anita Thyagarajan, Yanfang Chen, Jeffrey B. Travers, and Ravi P. Sahu. "Platelet-Activating Factor-Receptor Signaling Mediates Targeted Therapies-Induced Microvesicle Particles Release in Lung Cancer Cells." International Journal of Molecular Sciences 21, no. 22 (2020): 8517. http://dx.doi.org/10.3390/ijms21228517.

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Microvesicle particles (MVP) secreted by a variety of cell types in response to reactive oxygen species (ROS)-generating pro-oxidative stressors have been implicated in modifying the cellular responses including the sensitivity to therapeutic agents. Our previous studies have shown that expression of a G-protein coupled, platelet-activating factor-receptor (PAFR) pathway plays critical roles in pro-oxidative stressors-mediated cancer growth and MVP release. As most therapeutic agents act as pro-oxidative stressors, the current studies were designed to determine the role of the PAFR signaling i

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2

Thyagarajan, Anita, Sayali Kadam, Langni Liu, et al. "Gemcitabine Induces Microvesicle Particle Release in a Platelet-Activating Factor-Receptor-Dependent Manner via Modulation of the MAPK Pathway in Pancreatic Cancer Cells." International Journal of Molecular Sciences 20, no. 1 (2018): 32. http://dx.doi.org/10.3390/ijms20010032.

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Studies, including ours, have shown that pro-oxidative stressors, such as chemotherapeutic agents, generate oxidized lipids with agonistic platelet-activating factor (PAF) activity. Importantly, recent reports have implicated that these PAF-agonists are transported extracellularly via microvesicle particles (MVPs). While the role of PAF-receptor (PAF-R) has been implicated in mediating chemotherapy effects, its significance in chemotherapy-mediated MVP release in pancreatic cancer has not been studied. The current studies determined the functional significance of PAF-R in gemcitabine chemother

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3

Lazenby, Michelle, Oliver G. Ottmann, Keith Wilson, Caroline Alvares, and Joanna Zabkiewicz. "Extracellular Microvesicle Cytokines Secreted from Bone Marrow Mesenchymal Cells Mediate Proliferative and Survival Advantage in Acute Myeloid Leukaemia." Blood 132, Supplement 1 (2018): 2744. http://dx.doi.org/10.1182/blood-2018-99-113342.

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Abstract Background Haematopoietic stem cell transplantation is still the most effective anti-leukaemic therapy for AML treatment for a large number of patients, but a significant proportion of these will relapse post-transplant and the probability of long term survival is low. The bone marrow microenvironment has been implicated as a major contributor to chemotherapy resistance and relapse through mediating interactions between residual haematopoietic stem cells (HSC), leukaemic stem cells (LSC) and mesenchymal stem cells (MSC) which have been shown to support and maintain the leukaemic niche

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4

Travers, Jeffrey B., Joyce G. Rohan, and Ravi P. Sahu. "New Insights Into the Pathologic Roles of the Platelet-Activating Factor System." Frontiers in Endocrinology 12 (March 15, 2021). http://dx.doi.org/10.3389/fendo.2021.624132.

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Described almost 50 years ago, the glycerophosphocholine lipid mediator Platelet-activating factor (PAF) has been implicated in many pathologic processes. Indeed, elevated levels of PAF can be measured in response to almost every type of pathology involving inflammation and cell damage/death. In this review, we provide evidence for PAF involvement in pathologic processes, with focus on cancer, the nervous system, and in photobiology. Importantly, recent insights into how PAF can generate and travel via bioactive extracellular vesicles such as microvesicle particles (MVP) are presented. What ap

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Dissertations / Theses on the topic "Microvesicle particles MVP"

1

Christian, Lea Rajeshkumar. "Xeroderma Pigmentosum A Deficiency Results in Increased Generation of Microvesicle Particles in Response to Ultraviolet B Radiation." Wright State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=wright1621875551264658.

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Awoyemi, Azeezat Afolake. "Regulation of Microvesicle Particle release in keratinocytes." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1533682055929687.

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3

Fahy, Katherine Erin. "Thermal Burn Injury Induced Microvesicle Particle Release." Wright State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=wright149383031006972.

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