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Journal articles on the topic 'Middlesex Hospital (London)'

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Published: 4 June 2021
Last updated: 27 July 2025

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1

Hill, Oscar. "Alfred William Beard, Middlesex Hospital, London." Psychiatric Bulletin 16, no. 01 (1992): 63–64. http://dx.doi.org/10.1192/s0955603600106890.

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2

Adebayo, Shirley. "Health check." Nursery World 2023, no. 10 (2023): 33. http://dx.doi.org/10.12968/nuwa.2023.10.33.

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In this series by senior health visitors, Shirley Adebayo, a senior health visitor at North Middlesex University Hospital, London, talks about stages of speech and language development following a case of pre-verbal three-year-old boys
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3

McLoughlin, Liam. "Churchill’s fractured neck of femur." Journal of Medical Biography 27, no. 3 (2019): 129–36. http://dx.doi.org/10.1177/0967772018785858.

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In June 1962 at the age of 87 years, Sir Winston Churchill (1874–1965) fell over in his hotel room at the Hotel de Paris in Monte Carlo and sustained a fracture to the neck of his left femur. He was flown back to London and the fracture operated on at The Middlesex Hospital by two eminent orthopaedic surgeons, Mr Phillip Newman (1911–1994), Consultant to the The Middlesex Hospital and The Royal National Orthopaedic Hospital, Stanmore, and The Institute of Orthopaedics, London, and Professor Herbert Seddon (1903–1977), Consultant to the The Royal National Orthopaedic Hospital, Stanmore, and Dir
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4

Coker, R. J., N. Desmond, M. Poznansky, et al. "Experience of HIV Disease in a London District General Hospital." International Journal of STD & AIDS 6, no. 1 (1995): 47–49. http://dx.doi.org/10.1177/095646249500600110.

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The aim of this paper is to describe and discuss the experience of HIV disease in Central Middlesex Hospital, London up to June 1993. A retrospective study of the total number of HIV-positive patients cared for was performed. In addition, prospectively collected data as part of local epidemiological surveillance from January 1987 to June 1993 on all HIV test requests was analysed. Between January 1987 and June 1993 3695 individuals were tested for HIV-1 antibody at Central Middlesex Hospital. Of these, 101 HIV-1 seropositive individuals were identified and have attended this District General H
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Mant, Madeleine. "‘A Little Time Woud Compleat the Cure’: Broken Bones and Fracture Experiences of the Working Poor in London’s General Hospitals During the Long Eighteenth Century." Social History of Medicine 33, no. 2 (2018): 438–62. http://dx.doi.org/10.1093/shm/hky023.

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Summary This article draws upon admission and discharge records from four of London’s voluntary general hospitals (St Thomas’, Guy’s, Middlesex and London) to examine the fracture causes and experiences of the working poor. The article reveals that in-patients generally spent sufficient time in the hospital for significant fracture healing to occur. The diagnosis of fracture is considered within the context of Enlightenment medical education, pathological collections and contemporary clinical nosology. Using surgeons’ and physicians’ clinical notebooks, this article illustrates the fracture tr
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Katona, C. L. E., and M. M. Robertson. "Who makes it in psychiatry: CV predictors of success in training grades." Psychiatric Bulletin 17, no. 1 (1993): 27–29. http://dx.doi.org/10.1192/pb.17.1.27.

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A recent paper by Lewis (1991) found authorship of a publication to be the only variable that significantly predicted whether applicants for a senior registrar (SR) rotation in psychiatry at a London teaching hospital were shortlisted. We have re-examined curriculum vitae (CV) predictors of shortlisting at SR level within a comparable London teaching hospital rotation (University College and Middlesex Medical School, UCMSM), and extended the study to examine applicants for the corresponding SHO/registrar (REG) rotation. We have also compared the two groups in terms of demographic data and acad
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7

Aboud, Zainab, R. Balasubramanian, and R. Vashisht. "Evaluation of lymphoedema at West Middlesex University Hospital and assessment practice across West London Hospitals." European Journal of Surgical Oncology (EJSO) 35, no. 11 (2009): 1222. http://dx.doi.org/10.1016/j.ejso.2009.07.076.

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8

Baron, J. H. "Frederick Cayley Robinson's Acts of Mercy murals at the Middlesex Hospital, London." BMJ 309, no. 6970 (1994): 1723–24. http://dx.doi.org/10.1136/bmj.309.6970.1723.

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9

Parisaei, M., A. Govind, J. Clements, P. Arora, H. Lashkari, and P. Kapila. "Prevalence of vitamin D deficiency in a North London antenatal population." Obstetric Medicine 4, no. 3 (2011): 113–16. http://dx.doi.org/10.1258/om.2011.110049.

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Objective We evaluated the prevalence of vitamin D deficiency in the antenatal patients attending North Middlesex University Hospital between March 2008 and March 2009. Study design A prospective study of maternal levels of vitamin D at booking. Results The prevalence of both deficient and insufficient levels of 25[OH]D was 87.6% across all included patients. Conclusion There is a high prevalence of asymptomatic vitamin D deficiency in the antenatal booking population.
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10

Shields, D. A., S. Andaz, R. D. Abeysinghe, J. B. Porter, J. H. Scurr, and P. D. Coleridge Smith. "Plasma Lactoferrin as a Marker of White Cell Degranulation in Venous Disease." Phlebology: The Journal of Venous Disease 9, no. 2 (1994): 55–58. http://dx.doi.org/10.1177/026835559400900203.

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Objective: To measure plasma lactoferrin as a marker of neutrophil degranulation in groups of patients with varying severity of venous disease and compare with age- and sex-matched control subjects. Design: Prospective study of patients with varicose veins compared with a group of control subjects with no history or clinical findings of varicose veins. Setting: The Middlesex Hospital Vascular Laboratory, Mortimer Street, London WIN 8AA, UK. Patients: Patients referred to the Middlesex Hospital Vascular Laboratory for investigation of venous disease. Control subjects were obtained from within t
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11

AIRD, L. A., and P. H. S. SILVER. "Women doctors from The Middlesex Hospital Medical School (University of London) 1947-67." Medical Education 5, no. 3 (2009): 232–41. http://dx.doi.org/10.1111/j.1365-2923.1971.tb01828.x.

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12

Cybulska, E. "Continuing educational forum in psychogeriatrics for professional carers in the community." Psychiatric Bulletin 19, no. 11 (1995): 689–90. http://dx.doi.org/10.1192/pb.19.11.689.

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It has been common knowledge that professional carers in the community, institutions, and perhaps also in hospitals lack appropriate training in issues related to mental health problems in the elderly. Many crises in the community appear to be precipitated not so much by the gravity of the problems the elderly pose, but by panic or the fear of the unknown among the carers. Arie et al (1985) postulate that the joint teaching of different professions can be a fruitful training for subsequent team work, while Beynon & Croker (1983) reported that shared tutorials in geriatrics at the Middlesex
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13

Ozer, Mikail, Isil Thrasher, and Raj Sekaran. "Paediatric Psychosocial Emergencies in Two Inner-City London Hospitals: Review of the Current Management and Critical Evaluation Using NICE Self-Harm Quality Standards (QS34)." BJPsych Open 8, S1 (2022): S106. http://dx.doi.org/10.1192/bjo.2022.324.

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AimsThe paediatric wards support many children presenting with psychosocial crises. This has been increasing in recent years. NICE quality standards recommend that children who have self-harmed receive: a comprehensive psychosocial assessment, are assessed within 24 hours of referral if at high risk of suicide, a collaboratively developed risk management plan and monitoring to reduce risk of further self-harm. We aim to measure the number of referrals made by hospitals for acute psychiatric presentations and the adherence to the above quality standards by the Service for Adolescent and Familie
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14

Shields, D. A., S. K. Andaz, J. B. Porter, J. H. Scurr, and P. D. Coleridge Smith. "Soluble Markers of Leucocyte Adhesion in Patients with Venous Disease." Phlebology: The Journal of Venous Disease 12, no. 3 (1997): 82–85. http://dx.doi.org/10.1177/026835559701200302.

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Objective: To measure soluble CD54 (ICAM-1) and CD62E (E-selectin) as markers of neutrophil adhesion in four groups of patients with varying severity of venous disease and compare the values obtained with those in age- and sex-matched control subjects. Design: Prospective study of patients with varicose veins compared with a group of control subjects with no history or clinical findings of varicose veins. Setting: The Middlesex Hospital Vascular Laboratory, London. Patients: Patients referred to the Middlesex Hospital Vascular Laboratory for investigation of venous disease. Neither patients no
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15

Munro, Christina H., Ruth Henniker-Major, Virginia Homfray, and Rita Browne. "Improving the antenatal and post-partum management of women presenting to Sexual Health Services with positive syphilis serology through audit." International Journal of STD & AIDS 28, no. 9 (2017): 929–31. http://dx.doi.org/10.1177/0956462417691443.

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The incidence of congenital syphilis remains low in the UK, but the morbidity and mortality to babies born to women who are untreated for the condition make testing for the disease antenatally one of the most cost-effective screening programmes. Women attending North Middlesex Hospital, UK with a positive syphilis test at their antenatal booking visit are referred to St Ann’s Sexual Health Clinic, London, for management and contact tracing. We were concerned that our initial audit revealed that a large proportion of women referred to our service never attended and recorded partner notification
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16

Felder, S. L., and M. Davis. "LO37: Routine application of defibrillation pads and time to first shock in prehospital STEMI complicated by cardiac arrest." CJEM 19, S1 (2017): S40. http://dx.doi.org/10.1017/cem.2017.99.

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Introduction: ST-segment elevation myocardial infarction (STEMI) remains a significant cause of morbidity and mortality in North America, with recent studies suggesting that between 4 to 11% of patients diagnosed with STEMI suffer an out-of-hospital-cardiac arrest (OHCA). Previously published research has shown that shorter time to initial defibrillation in patients with VF/VT OHCA increases functional survival. The purpose of this study is to assess whether the routine application of defibrillation pads in STEMI decreases the time to initial defibrillation in those who suffer OHCA. Methods: A
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17

Shields, D. A., S. Andaz, R. D. Abeysinghe, J. B. Porter, J. H. Scurr, and P. D. Coleridge Smith. "Neutrophil Activation in Experimental Venous Hypertension." Phlebology: The Journal of Venous Disease 9, no. 3 (1994): 119–24. http://dx.doi.org/10.1177/026835559400900307.

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Objective: To investigate the white cell trapping hypothesis of venous ulceration by measuring plasma lactoferrin as a marker of neutrophil degranulation in normal volunteers in two experimental models of venous hypertension. Design: A prospective study of volunteers with no history or clinical evidence of venous disease. Setting: The Middlesex Hospital Vascular Laboratory, Mortimer Street, London WIN 8AA, UK. Patients: Volunteers within the Middlesex Hospital Vascular Laboratory with no history or clinical findings of venous or arterial disease, no other systemic disease, on no medication kno
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18

Planskoy, B., P. D. Tapper, A. M. Bedford, and F. M. Davis. "Physical aspects of total-body irradiation at the Middlesex Hospital (UCL group of hospitals), London 1988 - 1993: II.In vivoplanning and dosimetry." Physics in Medicine and Biology 41, no. 11 (1996): 2327–43. http://dx.doi.org/10.1088/0031-9155/41/11/006.

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19

Lomas, Howard. "The Development of the BABP." Behavioural Psychotherapy 19, no. 2 (1991): 211–15. http://dx.doi.org/10.1017/s0141347300012246.

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On a cold and dull Autumn Friday in 1972, I was among hordes of Behaviour Changers/Modifiers/Engineers/Therapists (all to become Psychotherapists) making their way from the four corners of Britain to the Middlesex Hospital in London. We were all going to a meeting to discuss the setting up of a National Association for those interested in Behavioural … whatever. When I arrived, I was refused entry unless I paid £3 annual membership fee to the very smartly dressed bouncer on the door who claimed to be the Treasurer. “But I thought the meeting was to decide if we are going to form an Association
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20

Vinson, Gavin P., and John P. Coghlan. "James Francis Tait. 1 December 1925—2 February 2014." Biographical Memoirs of Fellows of the Royal Society 65 (September 5, 2018): 381–404. http://dx.doi.org/10.1098/rsbm.2018.0015.

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James F. Tait FRS, with his wife Sylvia A. S. Tait FRS, made an indelible contribution to life science and medicine with the isolation and characterization of aldosterone, the most potent mineralocorticoid hormone produced by the mammalian adrenal cortex. Trained as a physicist, Tait turned to endocrinology during his first academic appointment at the Medical School of the Middlesex Hospital in London, where he met Sylvia. Their collaboration resulted in this major achievement within five years of his appointment, and they were both elected to fellowships of the Royal Society in 1959, when Jam
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21

Benson, Jack, Tara Amin, Diana Shroff, and Kirsty Allen. "Improving Clozapine Prescribing at a London District General Hospital: A Quality Improvement Project." BJPsych Open 10, S1 (2024): S130. http://dx.doi.org/10.1192/bjo.2024.351.

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AimsThe liaison psychiatry team at North Middlesex Hospital (NMH) noticed that many patients on clozapine were missing doses in hospital, risking the need for re-titration and deterioration in mental state. Although clozapine is a widely used medication in psychiatry, non-psychiatric clinicians may not be aware of the importance of compliance. In addition, clozapine is often not widely available in acute medical hospitals and ascertaining the correct dosage can be difficult as it is not prescribed by the GP. Furthermore, clozapine can cause a variety of side effects that our medical colleagues
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22

Bunker, D. L. J., G. Pappas, P. Moradi, and M. B. Dowd. "RADIOGRAPHIC SIGNS OF STATIC CARPAL INSTABILITY WITH DISTAL END RADIUS FRACTURES: IS CURRENT TREATMENT ADEQUATE?" Hand Surgery 17, no. 03 (2012): 325–30. http://dx.doi.org/10.1142/s0218810412500256.

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Patients presenting with distal end radius fractures may have concomitant carpal instability due to disruption of the scapholunate ligament. This study examined the incidence of static radiographic signs of carpal instability in patients with distal radial fractures before and after fracture treatment. We performed a retrospective radiographic study of 141 patients presenting to Central Middlesex Hospital, London between January 2002–May 2004 with distal end radius fractures. We used abnormal scapholunate angle as the primary indicator of possible carpal dissociation. Abnormal scapholunate ang
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Shami, S. K., S. J. Chittenden, J. H. Scurr, and P. D. Coleridge Smith. "Skin Blood Flow in Chronic Venous Insufficiency." Phlebology: The Journal of Venous Disease 8, no. 2 (1993): 72–76. http://dx.doi.org/10.1177/026835559300800207.

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Objective: To evaluate the skin temperature, laser Doppler flux (LDF), concentration of moving blood cells (CMBC) and speed of blood cells (SBC) in the liposclerotic and clinically normal skin of patients with chronic venous insufficiency. Design: Parallel groups study comparing patients with chronic venous insufficiency with control subjects. Setting: Vascular laboratory, Middlesex Hospital, University College and Middlesex School of Medicine, London, UK. Participants: Twenty patients with lipodermatosclerosis and chronic venous insufficiency comprised the disease group, and 15 subjects witho
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Planskoy, B., A. M. Bedford, F. M. Davis, P. D. Tapper, and L. T. Loverock. "Physical aspects of total-body irradiation at the Middlesex Hospital (UCL group of hospitals), London 1988 - 1993: I. Phantom measurements and planning methods." Physics in Medicine and Biology 41, no. 11 (1996): 2307–26. http://dx.doi.org/10.1088/0031-9155/41/11/005.

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Walsh, Julie, and Julie Walsh. "Oliver Sacks." Exchanges: The Interdisciplinary Research Journal 1, no. 1 (2013): 1–11. http://dx.doi.org/10.31273/eirj.v1i1.69.

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Renowned neurologist and author Dr Oliver Sacks is a visiting professor at the University of Warwick as part of the Institute of Advanced Study. Dr Sacks was born in London. He earned his medical degree at the University of Oxford (Queen’s College) and the Middlesex Hospital (now UCL), followed by residencies and fellowships at Mt. Zion Hospital in San Francisco and at University of California Los Angeles (UCLA). As well as authoring best-selling books such as Awakenings and The Man Who Mistook His Wife for a Hat, he is clinical professor of neurology at NYU Langone Medical Center in New York.
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Abu-Own, A., J. H. Scurr, and P. D. Coleridge Smith. "Assessment of Intermittent Pneumatic Compression by Strain-Gauge Plethysmography." Phlebology: The Journal of Venous Disease 8, no. 2 (1993): 68–71. http://dx.doi.org/10.1177/026835559300800206.

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Objective: To compare the physiological effects of a sequential gradient pneumatic compression device (SCD) with a single-chamber pneumatic compression device (Venodyne). Design: Single patient group with treatment crossover. Setting: Department of Surgery, University College and Middlesex Hospital, London, UK. Subjects: Thirty-four limbs of 17 normal adult volunteers were studied. Interventions: Sequential gradient compression was applied to one leg and single-chamber compression to the other lower limb for 10 min. The compression devices were then swapped to the opposite leg for a further 10
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Lees, AJ. "1 Soulful neurology." Journal of Neurology, Neurosurgery & Psychiatry 91, no. 8 (2020): e1.2-e1. http://dx.doi.org/10.1136/jnnp-2020-bnpa.1.

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Born on Merseyside, Andrew Lees qualified in medicine at the Royal London Hospital Medical College in 1970. His neurological training was at University College London Hospitals and the National Hospital for Neurology and Neurosurgery, Queen Square. He also spent 1 year at L’Hopital Salpetriere, Paris. He has achieved international recognition for his work on Parkinson’s disease and abnormal movement disorders. He is an original member of the Highly-Cited Researchers ISI Database with an h-index of 130. Founder member of the international Movement Disorder Society, he was elected President (200
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Pawa, S., K. Van Aarsen, A. Dukelow, D. Lizotte, and M. Zheng. "MP04: Interim analysis of the impact of the Emergency Department Transformation System on ambulance offload delay." CJEM 19, S1 (2017): S66. http://dx.doi.org/10.1017/cem.2017.170.

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Introduction: Emergency Department Systems Transformation (EDST) is a bundle of Toyota Production System based interventions implemented in two London, Canada tertiary care Emergency Departments (ED) between April 2014 and July 2016 to improve patient care by increasing value and reducing waste. Some of the 17 primary interventions included computerized physician order entry optimization, staff schedule realignment, physician scorecards, and a novel initial assessment process. Offload delays are associated with longer hospital length of stay and delayed admission, and may increase morbidity an
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Hollingsworth, S. J., C. B. Tang, and S. G. E. Barker. "Primary Varicose Veins in the Presence of an Intact Sapheno-Femoral Junction." Phlebology: The Journal of Venous Disease 16, no. 2 (2001): 68–72. http://dx.doi.org/10.1177/026835550101600204.

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Objective: To determine the incidence of primary varicose veins (VVs) occurring in the presence of a competent sapheno-femoral junction. Methods: A retrospective analysis of venous duplex scans was performed for all patients referred to the Vascular Unit, The Middlesex Hospital, London, for assessment of primary VVs, over an 18 month period from 1998 to 2000. Results: One thousand nine hundred and eleven patients with primary VVs referred to hospital for treatment were assessed. Their median age was 52 years (interquartile range 39–64 years). The female:male ratio was 1.92:1. Of these, 43.5% h
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Hassaan, Amro, and Aaron Trinidade. "The tinnitus patient information pack: usefulness in intrusive tinnitus." International Journal of Health Care Quality Assurance 32, no. 2 (2019): 360–65. http://dx.doi.org/10.1108/ijhcqa-03-2018-0071.

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Purpose The purpose of this paper is to determine a tinnitus patient information pack’s (TPIP) usefulness in patients suffering with tinnitus with respect to their need for further tinnitus retraining therapy (TRT) and in reducing TRT cancellations and non-attenders. Design/methodology/approach The paper consists of prospective case series in a district general hospital ENT out-patient department. Findings Patients with tinnitus-related symptoms constitute around 2 per cent of the ENT OPD workload at the West Middlesex Hospital, Chelsea & Westminster NHS Trust, London, i.e., 365 patients w
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West, J. B. "Alexander M. Kellas and the physiological challenge of Mt. Everest." Journal of Applied Physiology 63, no. 1 (1987): 3–11. http://dx.doi.org/10.1152/jappl.1987.63.1.3.

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Alexander M. Kellas (1868–1921) was a British physiologist who made pioneering contributions to the exploration of Everest and to the early physiology of extreme altitudes, but his physiological contributions have been almost completely overlooked. Although he had a full-time faculty position at the Middlesex Hospital Medical School in London, he was able to make eight expeditions to the Himalayas in the first two decades of the century, and by 1919 when the first official expedition to Everest was being planned, he probably knew more about the approaches than anybody else. But his most intere
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Campbell, Michelle, Joan S. Henthorn, and Sally C. Davies. "Evaluation of Cation-Exchange HPLC Compared with Isoelectric Focusing for Neonatal Hemoglobinopathy Screening." Clinical Chemistry 45, no. 7 (1999): 969–75. http://dx.doi.org/10.1093/clinchem/45.7.969.

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Abstract Background: Central Middlesex Hospital, in northwest London, has screened neonates for hemoglobinopathies, using the established manual technique of isoelectric focusing (IEF) since 1989. Recently, this laboratory has faced a large increase in the number of samples tested per year. This study compared the detection of hemoglobin abnormalities between the existing manual IEF method and that of automated cation-exchange HPLC to determine the reliability of HPLC and whether an automated system would save time in the laboratory. Methods: Over a 15-month period, 25 750 blood samples, colle
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Enoch, Jamie, Arevik Ghulakhszian, David P. Crabb, Christiana Dinah, and Deanna J. Taylor. "Acceptability of intravitreal injections in geographic atrophy: protocol for a mixed-methods pilot study." BMJ Open 11, no. 4 (2021): e049495. http://dx.doi.org/10.1136/bmjopen-2021-049495.

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IntroductionAge-related macular degeneration (AMD) is a common cause of visual impairment, affecting central vision. Geographic atrophy (GA) is an advanced form of the non-neovascular (dry) type of AMD. Late-stage clinical trials suggest that intravitreal injections of novel therapeutics may slow down the rate of GA progression by up to 30% in 1 year, thus allowing people with GA to preserve central vision for a longer period. While intravitreal injections have become an established treatment modality for neovascular (wet) AMD, it is unknown whether patients with (more gradually progressing) G
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Farrukh, Affifa, and John Francis Mayberry. "Inflammatory Bowel Disease in Turkish Populations Served by English NHS Trusts." Gastrointestinal Disorders 5, no. 3 (2023): 376–82. http://dx.doi.org/10.3390/gidisord5030031.

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It is estimated that there are about 500,000 Turkish people living in the UK, of whom about 300,000 are of Cypriot origin. A Freedom of Information request was sent to the four NHS Trusts in London which served areas with significant Turkish communities. The request sought information on the total number of patients admitted between 2016 and 2020 with inflammatory bowel disease. Between 2016 and 2020, 1936 patients with inflammatory bowel disease were admitted to North Middlesex University Hospital NHS Trust. Some of these patients will have been readmitted in different years, leading to an in
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Jarmain, Sarah, Eric Wong, Judith Francis, Lisa Vreugdenhil, and Arlene MacDougall. "Collaborative Networks: a Pragmatic and Innovative Approach to Meet the Mental Health and Addictions Care Crisis." International Journal of Integrated Care 23, S1 (2023): 341. http://dx.doi.org/10.5334/ijic.icic23671.

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Summary: In this highly interactive workshop, participants will learn how a unique implementation of the University of Washington AIMS Centre Collaborative Care Model (CoCM) for Mental Health and Addictions, within an interdisciplinary primary care setting, can improve access, clinical outcomes, and patient satisfaction by leveraging a population health approach, care management, and digital health technologies through creation of a network across organizations using existing resources.
 Background and Context: Mental health and substance use disorders are the leading cause of years lost
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Dukelow, A., M. Lewell, J. Loosley, S. Pancino, and K. Van Aarsen. "P035: Impact of EMS direct referral to community care on emergency department utilization." CJEM 21, S1 (2019): S75. http://dx.doi.org/10.1017/cem.2019.226.

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Introduction: The Community Referral by Emergency Medical Services (CREMS) program was implemented in January 2015 in Southwestern Ontario. The program allows Paramedics interacting with a patient to directly refer those in need of home care support to their local Community Care Access Centre (CCAC) for needs assessment. If indicated, subsequent referrals are made to specific services (e.g. nursing, physiotherapy and geriatrics) by CCAC. Ideally, CREMS connects patients with appropriate, timely care, supporting individual needs. Previous literature has indicated CREMS results in an increase of
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Gotlieb, Vladimir K., and Khine Z. Oo. "Marijuana Use and Sickle Cell Disease." Blood 112, no. 11 (2008): 4826. http://dx.doi.org/10.1182/blood.v112.11.4826.4826.

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Abstract A 45-year old Jamaican man with sickle cell disease came to our clinic complaining of chronic left ankle ulcer for one year. He stated that when he was a young boy he had had several hospital admissions for sickle cell crisis, usually precipitated by physical activity or infection, once or twice per month. We were surprised to find out that he had never had a crisis since the age of fifteen. We doubted his diagnosis yet his hemoglobin electrophoresis revealed HbS was 94.7%, HbF was 0.6% and HbA2 was 4.7%. He denied taking any medication. However, he admitted smoking 4 to 5 cigarettes
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Keithley, Joyce K. "Do patients with moderately impaired gastrointestinal function requiring enteral nutrition need a predigested nitrogen source? A prospective crossover controlled clinical trial R REES, W HARE, G GRIMBLE, ET AL Central Middlesex Hospital, and Zoological Society, London." Nutrition in Clinical Practice 8, no. 2 (1993): 80–81. http://dx.doi.org/10.1177/088453369300800213.

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Anyanwu, Ani C., Chris A. Rogers, and Andrew J. Murday. "Variations in cardiac transplantation: comparisons between the United Kingdom and the United States∗∗For the Uk Cardiothoracic Transplant Audit SteeringGroup.22Members of Steering Group and participating centers: Robert S. Bonser (Queen Elizabeth Hospital, Birmingham); John Dark (Freeman Hospital, Newcastle); Abdul K. Deiraniya (Wythenshawe Hospital, Manchester); Dr. Peter Doyle (Department of Health representative); Marc R. de Leval (Great Ormond Street Hospital for Children, London); Timothy J. Locke (Northern General Hospital, Sheffield); Andrew J. Murday (St George’s Hospital, London); John Wallwork (Papworth Hospital, Cambridge); Prof. David J. Wheatley (Glasgow Royal Infirmary, Glasgow); and Prof. Sir Magdi Yacoub (Harefield Hospital, Middlesex)." Journal of Heart and Lung Transplantation 18, no. 4 (1999): 297–303. http://dx.doi.org/10.1016/s1053-2498(98)00051-5.

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Owen, Elizabeth J., Peter Holownia, Gerard S. Conway, Howard S. Jacobs та John W. Honour. "11β-Hydroxyandrostenedione in plasma, follicular fluid, and granulosa cells of women with normal and polycystic ovaries**Financial support was provided by the Special Trustees of University College and Middlesex Hospital and the Brasher Marathon Research Fund, London, United Kingdom." Fertility and Sterility 58, № 4 (1992): 713–18. http://dx.doi.org/10.1016/s0015-0282(16)55317-5.

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Spoudeas, Helen A., Andy P. Winrow, Peter C. Hindmarsh, and Charles GD Brook. "Low-dose growth hormone-releasing hormone tests: a dose–response study." European Journal of Endocrinology 131, no. 3 (1994): 238–45. http://dx.doi.org/10.1530/eje.0.1310238.

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Spoudeas HA, Winrow AP, Hindmarsh PC, Brook CGD. Low-dose growth hormone-releasing hormone tests: a dose-response study. Eur J Endocrinol 1994;131:238–45. ISSN 0804–4643 We have evaluated parameters of the serum growth hormone (GH) concentration response to saline and 1-, 10- and 100-μg intravenous bolus doses of amide analogue of GH-releasing hormone (GHRH (1–29)NH2) given in random order to 10 adult male volunteers of median body weight 68 (60–90)kg. Compared with saline, both 10- and 100-μg GHRH(1–29)NH2 doses (but not 1 μg) resulted in significant peak GH responses (means and 95% confidenc
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Tayabali, Sarrah, Karen Madgwick, and Arne de Kreuk. "Allo-Immunisation in Sickle Cell Patients in a Large British Specialist Haemoglobinopathy Centre." Blood 134, Supplement_1 (2019): 2451. http://dx.doi.org/10.1182/blood-2019-130492.

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Background North Middlesex University Hospital (NMUH) is a 400 bed acute hospital in London, United Kingdom. The hospital is a specialist centre for the treatment of inherited red cell disorders caring for approximately 500 adult patients with Sickle Cell Anaemia (SCA) and performing a large number of emergency and elective blood transfusions including automated exchange transfusions, which are an increasingly important cornerstone in the treatment of SCA. In order to minimise risks of allo-immunisation, international guidelines recommend that sickle cell patients are fully phenotyped prior to
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Tyrer, Peter, Paul Salkovskis, Helen Tyrer, et al. "Cognitive–behaviour therapy for health anxiety in medical patients (CHAMP): a randomised controlled trial with outcomes to 5 years." Health Technology Assessment 21, no. 50 (2017): 1–58. http://dx.doi.org/10.3310/hta21500.

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BackgroundHealth anxiety is an under-recognised but frequent cause of distress that is potentially treatable, but there are few studies in secondary care.ObjectiveTo determine the clinical effectiveness and cost-effectiveness of a modified form of cognitive–behaviour therapy (CBT) for health anxiety (CBT-HA) compared with standard care in medical outpatients.DesignRandomised controlled trial.SettingFive general hospitals in London, Middlesex and Nottinghamshire.ParticipantsA total of 444 patients aged 16–75 years seen in cardiology, endocrinology, gastroenterology, neurology and respiratory me
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Peters, Marion G., H. W. Hann, Paul Martin, et al. "Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B 1 1The Adefovir Dipivoxil International 461 Study Group includes the following: N. Afdhal (Beth Israel Deaconess Medical Center, Boston, MA); P. Angus (Austin and Repatriation Medical Centre, Melbourne, Australia); Y. Benhamou (Hopital La Pitie Salpetriere, Paris, France); M. Bourliere (Hopital Saint Joseph, Marseille, France); P. Buggisch (Universitaetsklinikum Eppendorf, Department of Medicine, Hamburg, Germany); P. Couzigou (Hopital Haut Leveque, Pessac, France); P. Ducrotte and G. Riachi (Hopital Charles Nicolle, Rouen, France); E. Jenny Heathcote (Toronto Western Hospital, Toronto, Ontario, Canada); H. W. Hann (Jefferson Medical College, Philadelphia, PA); I. Jacobson (New York Presbyterian Hospital, New York, NY); K. Kowdley (University of Washington Hepatology Center, Seattle, WA); P. Marcellin (Hopital Beaujon, Clichy, France); P. Martin (Cedars-Sinai Medical Center, Los Angeles, CA); J. M. Metreau (Centre Hospitalier Universitaire Henri Mondor, Creteil, France); M. G. Peters (University of California, San Francisco, San Francisco, CA); R. Rubin (Piedmont Hospital, Atlanta, GA); S. Sacks (Viridae Clinical Sciences, Inc., Vancouver, Canada); H. Thomas (St. Mary’s Hospital, London, England); C. Trepo (Hopital Hôtel Dieu, Lyon, France); D. Vetter (Hopital Civil, Strasbourg, France); C. L. Brosgart, R. Ebrahimi, J. Fry, C. Gibbs, K. Kleber, J. Rooney, M. Sullivan, P. Vig, C. Westland, M. Wulfsohn, and S. Xiong (Gilead Sciences, Inc., Foster City, CA); D. F. Gray (GlaxoSmithKline, Greenford, Middlesex, England); R. Schilling and V. Ferry (Parexel International, Waltham, MA); and D. Hunt (Covance Laboratories, Princeton, NJ)." Gastroenterology 126, no. 1 (2004): 91–101. http://dx.doi.org/10.1053/j.gastro.2003.10.051.

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McKenzie, Kate, Saoirse Cameron, Natalya Odoardi, Katelyn Gray, Michael R. Miller, and Janice A. Tijssen. "Evaluation of Local Pediatric Out-of-Hospital Cardiac Arrest and Emergency Services Response." Frontiers in Pediatrics 10 (February 22, 2022). http://dx.doi.org/10.3389/fped.2022.826294.

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BackgroundSurvival after pediatric out-of-hospital cardiac arrest is poor. Paramedic services provide critical interventions that impact survival outcomes. We aimed to describe local pediatric out-of-hospital cardiac arrest (POHCA) events and evaluate the impact of the paramedic service response to POHCA.MethodsThe Canadian Resuscitation Outcomes Consortium and corresponding ambulance call records were used to evaluate deviations from best practice by paramedics for patients aged 1 day to <18 years who had an atraumatic out-of-hospital cardiac arrest between 2012 and 2020 in Middlesex-L
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Pantazis, Antonis. "Overview of Obstructive Hypertrophic Cardiomyopathy." EMJ Cardiology, December 8, 2022. http://dx.doi.org/10.33590/emjcardiol/10168110.

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Antonis Pantazis, Consultant Cardiologist at the Royal Brompton and Harefield Hospitals and North Middlesex University Hospital in London, UK, and Chairperson of the European Society of Cardiology (ESC) Working Group on Myocardial and Pericardial Diseases, provided an expert insight into the various aspects of obstructive hypertonic cardiomyopathy (HCM) during an EMJ- conducted podcast. Pantazis opened the podcast by providing a definition of HCM and describing this clinical condition, discussing the typical symptoms and diagnostic tests that can be performed. Pantazis then explained the demog
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Brook, S., R. Barnard, Y. Al-Haddawi, et al. "2545 The burden of frailty in a West London hospital: a case for an acute ‘front door’ team with robust links with community services." Age and Ageing 54, Supplement_1 (2025). https://doi.org/10.1093/ageing/afae277.037.

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Abstract Introduction Global estimates indicate over half of individuals aged 85 and older are frail (1), costing the UK healthcare system approximately £5.8 billion annually (2). Locally, over 6500 patients aged 65+ are admitted to West Middlesex University Hospital (WMUH) every six months. The proposed frailty team aims to implement early comprehensive geriatric assessments (CGAs) through a multidisciplinary approach. Timely CGAs can increase the likelihood of patients remaining in their own homes at 6 and 12 months (3), reduce length of stay (LoS), and lower healthcare costs, contingent upo
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Pastides, P. S., and W. Khan. "Rotator Cuff Injuries: The Evolving Role of Tissue Engineering." October 8, 2011. https://doi.org/10.5281/zenodo.7791.

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Aims: Rotator cuff injuries are a common injury associated with a combination of intrinsic and extrinsic causative factors. Although surgical reconstruction is a well established option, this is associated with variable re rupture rates. There is a growing body of interest in the potential tissue engineering in the management of rotator cuff injuries. This review aims to summarise the information in the literature on the evolving role of these techniques. Study design: Review Article Place and Duration of Study: University College London Institute of Orthopaedics and Musculoskeletal Sciences,
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Pastides, P. S., and W. S. Khan. "Cell-Based Therapies in Musculoskeletal Injuries: The Evolving Role of Bone Marrow- Derived Mesenchymal Stem Cells." September 28, 2011. https://doi.org/10.5281/zenodo.7797.

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Aims: There is considerable interest in the potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) in the management of musculoskeletal injuries. This review aims to summarise the information in the literature on the evolving role of these cells in the management of these complex heterogenous injuries. Study design: Review Article. Place and Duration of Study: University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, United Kingdom. Methodology: We reviewed the literature to identify studies o
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Pastides, P. S., and W. Khan. "Tendon and Ligament Injuries: The Evolving Role of Stem Cells and Tissue Engineering." September 29, 2011. https://doi.org/10.5281/zenodo.7792.

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Aims: Musculoskeletal injuries are a common injury associated with a reduction in quality of life, increased morbidity and social and financial implications. Although surgical reconstruction is a well established option, outcomes are variable. There is a growing body of interest in the potential of mesenchymal stem cells (MSCs) in the management of tendon and ligament injuries. This review aims to summarise the information in the literature on the evolving role of these. Study design: Review Article. Place and Duration of Study: University College London Institute of Orthopaedics and Musculosk
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