Academic literature on the topic 'Migraine with photophobia'

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Journal articles on the topic "Migraine with photophobia"

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Vanagaite, J., JA Pareja, O. St⊘ren, LR White, T. Sanc, and LJ Stovner. "Light-Induced Discomfort and Pain in Migraine." Cephalalgia 17, no. 7 (1997): 733–41. http://dx.doi.org/10.1046/j.1468-2982.1997.1707733.x.

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Quantitative thresholds for discomfort and pain with monocular and binocular light stimuli were measured in 67 controls and 67 migraine patients 37 migraine with aura and 30 migraine without aura). Patients were more photophobic during attack than outside attack ( p<0.03), and they were more sensitive to light than controls even between attacks ( p0001). We found no differences in light sensitivity between migraine with aura and migraine without aura ( p0.93). Unilateral pain affected light sensitivity on both sides. When asked with a questionnaire, 74% of patients answered that they were s
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Maheshkumar, Rajpura. "Compare Pupil Size in Migraine Patients with Photophobia versus Normal Subjects and Correlation of the Pupil Size to Severity of Headache." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 235–38. https://doi.org/10.5281/zenodo.14032657.

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This study suggests that patients with migraines and photophobia have significantly larger pupil sizes compared to normal subjects without headaches. The findings indicate a correlation between pupil size and the severity of migraine disability as measured by the Migraine Disability Assessment (MIDAS) test.  Migraine patients with photophobia had a mean pupil size of 4.89 mm, while normal subjects had a mean of 3.8 mm. The difference was statistically significant. Based on MIDAS grades, patients with more severe disability (Grade 4) had the largest pupil size, averaging 5.6 mm. This indic
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Nagata, Eiichiro, Motoharu Takao, Haruki Toriumi, et al. "Hypersensitivity of Intrinsically Photosensitive Retinal Ganglion Cells in Migraine Induces Cortical Spreading Depression." International Journal of Molecular Sciences 25, no. 14 (2024): 7980. http://dx.doi.org/10.3390/ijms25147980.

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Migraine is a complex disorder characterized by episodes of moderate-to-severe, often unilateral headaches and generally accompanied by nausea, vomiting, and increased sensitivity to light (photophobia), sound (phonophobia), and smell (hyperosmia). Photophobia is considered the most bothersome symptom of migraine attacks. Although the underlying mechanism remains unclear, the intrinsically photosensitive retinal ganglion cells (ipRGCs) are considered to be involved in photophobia associated with migraine. In this study, we investigated the association between the sensitivity of ipRGCs and migr
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Choi, J.-Y., K. Oh, B.-J. Kim, C.-S. Chung, S.-B. Koh, and K.-W. Park. "Usefulness of a Photophobia Questionnaire in Patients With Migraine." Cephalalgia 29, no. 9 (2009): 953–59. http://dx.doi.org/10.1111/j.1468-2982.2008.01822.x.

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Photophobia is an important criterion for the diagnosis of migraine. However, several Asian epidemiological surveys about migraine have shown lesser prevalence of photophobia than that of Western studies. This discrepancy is probably caused by underestimation of photophobia due to inappropriate questioning of patients by physicians. To investigate this issue, we developed a questionnaire about photophobia and evaluated its usefulness in 103 patients with migraine. In phase 1 of the study, we found good repeatability of the questionnaire with a 0.826 k coefficient. In phase 2, the prevalence of
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Villar-Martinez, María Dolores, and Peter J. Goadsby. "Dim the Lights: A Narrative Review of Photophobia in Migraine." Neurology 18, no. 1 (2022): 14. http://dx.doi.org/10.17925/usn.2022.18.1.14.

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A preference for darkness is one of the main associated features in people with migraine, the cause remaining a mystery until some decades ago. In this article, we describe the epidemiology of photophobia in migraine and explain the pathophysiological mechanisms following an anatomical structure. In addition, we review the current management of migraine and photophobia. Ongoing characterization of patients with photophobia and its different manifestations continues to increase our understanding of the intricate pathophysiology of migraine and vice versa. Detailed phenotyping of the patient wit
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Pinheiro, Carina F., Jessica R. Moreira, Gabriela F. Carvalho, Leticia Zorzin, Fabiola Dach, and Debora Bevilaqua-Grossi. "Interictal Photophobia and Phonophobia Are Related to the Presence of Aura and High Frequency of Attacks in Patients with Migraine." Applied Sciences 11, no. 6 (2021): 2474. http://dx.doi.org/10.3390/app11062474.

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Background: Despite that photophobia and phonophobia are well-known symptoms related to migraine, it is unclear whether they affect daily life activities during the headache-free period. Objective: To evaluate the interictal photophobia/phonophobia intensity during daily activities in migraineurs and non-headache individuals. Methods: Women with migraine without aura (MoA, n = 30), migraine with aura (MA, n = 30), chronic migraine (CM, n = 30) and without headache (CG, n = 30) reported the photophobia and phonophobia intensity during daily activities using a Likert scale ranging from 0 (no dis
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Molina, Omar Franklin, Zeila Coelho Santos, Laura Martins, et al. "Differentiating occipital neuralgia from migraine and tension-type headache." Revista Neurociências 22, no. 3 (2014): 425–31. http://dx.doi.org/10.34024/rnc.2014.v22.8071.

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Objective. To establish differential diagnosis in patients presenting occipital neuralgia, tension-type headache, and migraine with aura. Method. We analyzed 32 patients with Occipital neuralgia (mean age=38.0; females=75%), 102 with tension-type headache (mean age=33.0; females=92.2%), and 16 with migraine without aura (mean age=37.0; females=56.3%). The specific symptoms of headaches were used in according to International Classification of Headache Dis­orders (ICHD) in patients with for craniomandibular disorders and bruxing behavior. Results. Occipital neuralgia group presented more nausea
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Eren, Ozan E., Ruth Ruscheweyh, Andreas Straube, and Christoph J. Schankin. "Quantification of photophobia in visual snow syndrome: A case-control study." Cephalalgia 40, no. 4 (2019): 393–98. http://dx.doi.org/10.1177/0333102419896780.

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Objective To quantify photophobia in visual snow syndrome (VSS), a debilitating migraine-associated visual disturbance manifesting with continuous “TV snow-like” flickering dots in the entire visual field and additional visual symptoms, such as photophobia. Methods Photophobia was compared between 19 patients with VSS and 19 controls matched for age, sex, migraine and aura using the Leiden Visual Sensitivity Scale (L-VISS). Results Patients with VSS had an increased L-VISS-score compared to matched controls [(22.2 ± 5.9 vs. 4.4 ± 4.8; ANOVA, factors VSS and comorbid migraine: Main effect for V
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Kitagawa, Satoshi, Chunhua Tang, Miyuki Unekawa, Yohei Kayama, Jin Nakahara, and Mamoru Shibata. "Sustained Effects of CGRP Blockade on Cortical Spreading Depolarization-Induced Alterations in Facial Heat Pain Threshold, Light Aversiveness, and Locomotive Activity in the Light Environment." International Journal of Molecular Sciences 23, no. 22 (2022): 13807. http://dx.doi.org/10.3390/ijms232213807.

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A migraine is clinically characterized by repeated headache attacks that entail considerable disability. Many patients with migraines experience postdrome, the symptoms of which include tiredness and photophobia. Calcitonin gene-related peptide (GGRP) is critically implicated in migraine pathogenesis. Cortical spreading depolarization (CSD), the biological correlate of migraine aura, sensitizes the trigeminovascular system. In our previous study, CSD caused hypomotility in the light zone and tendency for photophobia at 72 h, at which time trigeminal sensitization had disappeared. We proposed t
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Borkowska, Agata, Anna Kiełb, Anna Mich, et al. "The use of triptans as an effective form of migraine treatment – review." Quality in Sport 37 (January 11, 2025): 56600. https://doi.org/10.12775/qs.2025.37.56600.

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Introduction Migraine, a prevalent neurological disorder, is characterized by recurrent episodes of moderate to severe headache, often accompanied by symptoms such as nausea, photophobia, and phonophobia. Triptans, which belong to the class of serotonin 5-HT1B/1D receptor agonists, are integral to the management of migraine, providing prompt relief from symptoms. Aim of the study To clarify how effective triptans are in treating migraines, highlighting their role in symptom relief and improving patients' quality of life Materials and methods The article is the result of a comprehensive analysi
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Dissertations / Theses on the topic "Migraine with photophobia"

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Kaiser, Eric Alan. "Effects of CGRP and light in mice: implications for photophobia and migraine." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/3114.

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Calcitonin gene-related peptide (CGRP) has been strongly implicated in the pathophysiology of migraine. CGRP levels are elevated during a migraine attack. Injection of CGRP can trigger a delayed migraine-like headache in migraineurs. Finally, CGRP receptor antagonists are effective antimigraine therapeutics. Consequently, a CGRP-sensitized mouse, nestin/hRAMP1 was genetically engineered to conditionally express a subunit of the CGRP receptor, hRAMP1, in neurons and glia. In response to CGRP, nestin/hRAMP1 mice demonstrated a significant decrease in time in the light zone of a dim light-dark bo
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Dey, Ashim. "Melanopsin photoreceptor contributions to brightness perception and photophobia." Thesis, Queensland University of Technology, 2020. https://eprints.qut.edu.au/205723/1/Ashim_Dey_Thesis.pdf.

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This thesis investigated the role of rod, cone and melanopsin photoreceptors in mediating human brightness perception across the natural operating range of the eye. In scotopic illumination, brightness perception is initiated by rod signals transmitted to higher brain centres via conventional retinogeniculate and melanopsin pathways. In mesopic illumination, melanopsin photoreception begins to scale brightness perception. In photopic illumination, melanopsin and cone luminance signals combine to mediate light hypersensitivity (photophobia) in healthy controls and migraineurs. These findings ad
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Mason, Bianca Nicole. "Sites of CGRP action in light aversive behavior: implications for migraine." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5966.

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Migraine is a complex neurological disorder that affects approximately 38 million Americans. For over 25 years, the neuropeptide calcitonin gene-related peptide (CGRP) has been implicated in the pathogenesis of migraine. In fact, several pharmaceutical companies are tailoring treatments to antagonize CGRP actions. However, due to the complexity of migraine, exactly how and where CGRP acts to contribute to migraine have remained controversial: whereas several studies suggest that CGRP acts in the central nervous system (CNS) in this context, others have indicated a role in the periphery. Centra
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Chanda, Mona Lisa. "Evidence of photophobia and lateralized head pain in the transgenic «Cacna1a» mouse model of migraine." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66687.

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Migraine is a highly prevalent, disabling and complex episodic brain disorder not known to occur in animals. The pathogenesis is poorly understood, largely due to the lack of validated animal models. Here we report behavioural evidence of hallmark migraine features, unilateral headache and photophobia, in a transgenic knock-in mouse bearing the human familial hemiplegic migraine, type 1 (FHM-1) R192Q gain-of-function mutation of the Cacna1a gene encoding the Cav2.1 calcium channel α1 subunit. Photophobia was demonstrated using a modified elevated plus maze test in which the safe cl
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Pinheiro, Carina Ferreira. "Desconforto induzido pela luz, controle postural e sintomas vestibulares em mulheres com migrânea - um estudo controlado." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17152/tde-01022019-102741/.

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Objetivos: Verificar a relação entre a incapacidade relacionada aos sintomas vestibulares e a presença de aura e cronicidade da migrânea. Além disso, investigar a sensibilidade visual em indivíduos com migrânea e sem cefaleia, bem como o controle de equilíbrio postural perante estimulação luminosa. Métodos: mulheres com migrânea e mulheres sem cefaleia foram avaliadas nos estudos apresentados nesta tese. Inicialmente, as mulheres com migrânea foram estratificadas em migrânea com aura, migrânea sem aura e migrânea crônica. Informações sobre sintomas vestibulares foram coletadas e a autopercepçã
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Books on the topic "Migraine with photophobia"

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Kaplan, Tamara, and Tracey Milligan. Headache and Facial Pain (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190650261.003.0003.

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The video in this chapter discusses headache and facial pain, including headaches due to another underlying cause (secondary headaches), migraine and its typical features (nausea, vomiting, photophobia, phonophobia, visual aura), trigeminal autonomic cephalgias (such as cluster headaches), and trigeminal neuralgia.
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Book chapters on the topic "Migraine with photophobia"

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Schain, Aaron, and Rami Burstein. "Sensitization and Photophobia in Migraine." In Neurobiological Basis of Migraine. John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781118967225.ch7.

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de Dhaem, Olivia Begasse. "My Right Eye Is On Fire." In Headache. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197659441.003.0014.

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Abstract The chapter “My Right Eye Is On Fire” examines the diagnosis, work-up, and management of neuropathic eye pain. The first step to eye pain and photophobia is to determine whether the etiology is central or peripheral. The pain is likely peripheral if monocular, with no red flags on history, no abnormalities on neurological exam, and abates with a topical anesthetic. If there is a concern for a central etiology, further work-up with imaging and possibly lumbar puncture depending on the history and exam findings is warranted. Once established to be peripheral, a thorough ophthalmologic e
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Mauskop, Alexander. "Typical cases." In Migraine and Headache. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195368208.003.0009.

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Abstract Abigail was a 32-year-old woman who had suffered from severe headaches for the past 15 years. Her headaches were unilateral, severe in intensity, and pulsatile, with photophobia and phonophobia but no nausea, and they were made worse by light physical activity. They occurred two or three times a month, and each attack lasted 3 days. Typical triggers were work-related stress, weather, and menstrual cycle. She had tried sumatriptan (Imitrex), 100 mg, eletriptan (Relpax) 40 mg, and zolmitriptan (Zomig) 5 mg, with no relief. Review of organ systems revealed anxiety, insomnia, some depress
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Mauskop, Alexander. "Classification and diagnosis of headaches." In Migraine and Headache. Oxford University PressNew York, NY, 2009. http://dx.doi.org/10.1093/oso/9780195368208.003.0001.

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Abstract The International Headache Society’s (IHS) highly detailed classification of headaches (appendix), now in its second edition, has become an important research tool, albeit with modest practical applications. Danish physician Jes Olesen was the major force behind this effort. Migraine diagnosis is based on the description of symptoms reported by patients. The most common type of migraine is migraine without aura, and its features include moderate or severe pain, unilateral location, throbbing quality of pain, worsening with light physical activity, sensitivity to light and noise, and n
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Onderwater, Gerrit L. J., and Michel D. Ferrari. "Visual snow." In Oxford Textbook of Headache Syndromes, edited by Michel Ferrari, Joost Haan, Andrew Charles, David W. Dodick, Fumihiko Sakai, and Christopher Kennard. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198724322.003.0059.

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Visual snow is characterized by continuous visual disturbances in the form of countless tiny particles present in the entire visual field, often interpreted as television static. The visual disturbances are almost always accompanied by additional symptoms, including palinopsia, nyctalopia, photophobia, entoptic phenomenon, bilateral tinnitus, concentration problems, lethargy, and irritability. Visual snow has been linked to migraine and the migrainous aura. The clinical phenotype of visual snow clearly different from migraine; however, the co-occurrence with migraine (aura) might imply that bo
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Rosmarin, Caryn. "Infection of the Central Nervous System." In Tutorial Topics in Infection for the Combined Infection Training Programme. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198801740.003.0043.

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Meningism is the syndrome of the triad of symptoms of headache, neck stiffness, and photophobia caused by irritation of the meninges. While it is often associated with a diagnosis of meningitis, it is also present in other conditions causing meningeal irritation such as subarachnoid haemorrhage, trigeminal neuralgia, migraine, or febrile illness in children. Meningitis is process of inflammation of the meninges, which may or may not be due to an infectious agent. Strictly speaking, it is a pathological diagnosis, but in lieu of the impracticability of biopsying the meninges, surrogate markers
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Conference papers on the topic "Migraine with photophobia"

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Bogatova, K. S., and O. V. Yakovleva. "STUDY OF MECHANICAL ALLODYNIA, PHOTOPHOBIA AND ANXIETY IN RATS WITH PRENATAL HYPERHOMOCYSTEINEMIA IN CHRONIC MIGRAINE CAUSED BY THE ADMINISTRATION OF NITROGLYCERIN." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-299.

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In this study, we analyzed the relationship of hyperhomocysteinemia (HHcy) with the development of migraine in male Wistar rats. Migraine modeling was carried out by repeated intraperitoneal administration of nitroglycerin. In rats with HHcy, a decrease in the threshold of mechanical sensitivity was revealed in the Von Frey test, and the development of anxiety and photophobia was also observed in the light-dark box test.
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Erthal, Jullyane Lutterbach, and Caroline Matos de Souza Franco Rêgo. "The relationship between tension headache and screen exposure in children and adolescents." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.307.

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Background: Primary headaches are idiopathic or genetic conditions without a known secondary cause. Primary tension-type headache is characterized by bilateral, non-throbbing pain, of mild to moderate intensity. Nowadays, with greater exposure to electronics, a relationship was observed between screen time and increased tension headache among children and adolescents. Objective: Elucidate the association between tension-type headache and increased screen exposure among children and adolescents. Methods: A literature review was carried out after analyzing scientific articles from 2014 to 2020,
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Oliveira, Igor Jacomedes de, Cíntia Gonçalves Nogueira, Gabriela Ferreira Paticcié, et al. "Headache Prevalence in a Specialized Center." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.411.

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Background: Headache is the most frequent neurological complaint in the population and the group of tension-type headaches (TTH) is the most prevalent subtype. Nevertheless, more information about the clinical features of headaches in patients attended at specialized centers are demanded. Methods: Cross-sectional, descriptive study. Data from patients referred to an outpatient specialized headache center from 2018 to 2019 were analyzed and clinical and epidemiological information was collected. This study was authorized by the research ethics committee of the HUUFJF (CAAE 03530818.9.0000.5133)
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