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Relevant bibliographies by topics / Milbemycin Oxime

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Academic literature on the topic 'Milbemycin Oxime'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Milbemycin Oxime"

1

Chable-Bessia, Christine, Charlotte Boullé, Aymeric Neyret, et al. "Low Selectivity Indices of Ivermectin and Macrocyclic Lactones on SARS-CoV-2 Replication In Vitro." COVID 2, no. 1 (2022): 60–75. http://dx.doi.org/10.3390/covid2010005.

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Ivermectin was first approved for human use as an endectocide in the 1980s. It remains one of the most important global health medicines in history and has recently been shown to exert in vitro activity against SARS-CoV-2. However, the macrocyclic lactone family of compounds has not previously been evaluated for activity against SARS-CoV-2. The present study aims at comparing their anti-viral activity in relevant human pulmonary cell lines in vitro. Here, in vitro antiviral activity of the avermectins (ivermectin and selamectin) and milbemycins (moxidectin and milbemycin oxime) were assessed a

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Gunnarsson, LK, LC Moller, AM Einarsson, et al. "Clinical efficacy of milbemycin oxime in the treatment of nasal mite infection in dogs." Journal of the American Animal Hospital Association 35, no. 1 (1999): 81–84. http://dx.doi.org/10.5326/15473317-35-1-81.

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A multicentric clinical trial was done to evaluate the clinical efficacy of milbemycin oxime in the treatment of nasal mite (Pneumonyssoides caninum) infection in dogs. Milbemycin oxime was given to 70 dogs of different breeds, genders, and ages, with clinical signs associated with nasal mite infection. Twenty-five dogs had a verified infection, and 45 dogs had signs suggestive of nasal mite infection. Milbemycin oxime was given at the dosage of 0.5 to 1.0 mg/kg body weight orally once a week for three consecutive weeks. One month after initiation of treatment, 68 of the dogs had no more clini

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Li, Ze-En, Yang-Guang Jin, Shao-Zu Hu, et al. "Design, Optimization, Manufacture and Characterization of Milbemycin Oxime Nanoemulsions." Pharmaceutics 17, no. 3 (2025): 289. https://doi.org/10.3390/pharmaceutics17030289.

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Background: Despite the rapid development of nanoemulsions in recent years, no method has been established for the preparation of milbemycin oxime nanoemulsions. Milbemycin oxime is a widely used macrolide antibiotic in veterinary medicine, particularly for treating parasitic infections in animals such as dogs. However, its poor solubility in water limits its bioavailability and therapeutic efficacy. Developing a nanoemulsion formulation can enhance its solubility, stability, and bioavailability, offering a more effective treatment option. Methods: In this experiment, oil-in-water (O/W) milbem

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Miller, William H., Danny W. Scott, Jocelyn R. Wellington, and Rada Panić. "Clinical efficacy of milbemycin oxime in the treatment of generalized demodicosis in adult dogs." Journal of the American Veterinary Medical Association 203, no. 10 (1993): 1426–29. http://dx.doi.org/10.2460/javma.1993.203.10.1426.

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Summary Thirty adult dogs with chronic generalized demodicosis were treated with oral administration of milbemycin oxime (0.52 to 3.8 mg/kg oj body weight, q 24 h). Results oj skin scrapings were used to determine whether administration oj milbemycin should be continued or discontinued. Dogs that were free of clinical signs of demodicosis 12 months after administration of milbemycin was discontinued were considered cured. Sixteen dogs were cured, 5 dogs were never cleared of mites, and 9 dogs were cleared of mites, but relapsed after administration of milbemycin was discontinued. Adverse effec

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Mukaseev, Sergey, and Orhan Zeynalov. "Tolerance study of anthelmintic drug Supramil® tablets in dogs and cats." Russian veterinary journal 2023, no. 3 (2023): 39–49. http://dx.doi.org/10.32416/2500-4379-2023-3-39-49.

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In an experiment on 30 dogs and 30 cats of different ages, the effect of the drug Supramil® tablets in twice and three times increased doses on the clinical condition, morphological and biochemical parameters of blood was studied. The drug was administered to dogs and puppies individually orally in two-fold (5.0 mg/ kg for R-praziquantel and 1.0 mg / kg for milbemycin oxime) and three-fold (7.5 mg / kg for R-praziquantel and 1.5 mg / kg for milbemycin oxime) therapeutic doses daily for 7 days with an interval of 24 hours. The drug was administered individually to cats and kittens orally in two

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Blagburn, Byron L., Charles M. Hendrix, David S. Lindsay, Joy L. Vaughan, Douglas I. Hepler, and James C. Wright. "Efficacy of milbemycin oxime against naturally acquired or experimentally induced Ancylostoma spp and Trichuris vulpis infections in dogs." American Journal of Veterinary Research 53, no. 4 (1992): 513–16. http://dx.doi.org/10.2460/ajvr.1991.53.04.513.

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Summary The efficacy of milbemycin oxime was evaluated at dosages of 0.25, 0.50 and 0.75 mg/kg of body weight in dogs naturally infected with mature Ancylostoma spp, at a dosage of 0.50 mg/kg in dogs with experimentally induced immature and mature A caninum, and at dosages of 0.55 to 0.86 mg/kg in dogs naturally infected with mature Trichuris vulpis. Milbemycin oxime was 95 and 99% effective against mature Ancylostoma spp at dosages of 0.50 and 0.75 mg/kg, respectively, but only 49% effective at a dosage of 0.25 mg/kg. Efficacy was 49% against pulmonary L3-L4 stages of A caninum (36 hours afte

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Wade, C. G., S. H. Mercer, D. I. Hepler, and T. M. Craig. "Effect of milbemycin oxime against Ancylostorna caninum in dogs with naturally acquired infection." American Journal of Veterinary Research 52, no. 6 (1991): 951–53. http://dx.doi.org/10.2460/ajvr.1991.52.06.951.

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SUMMARY Twenty-six mixed-breed (14 males, 12 females) dogs were used in a double-blind study to evaluate the effect of milbemycin oxime against naturally acquired infection with Ancylostorna caninum. Dogs were ranked and paired, on the basis of number of hookworm eggs/g of feces, and treatment was randomly assigned. Each dog was given either the study drug or placebo (1 tablet/11.4 kg [0.5 mg/ kg] of body weight). Eggs per gram of feces enumeration was done on days 3 and 7 after treatment, and dogs were euthanatized on day 7. On day 3, 5 of the 13 dogs in the milbemycin-treated group had hookw

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Tranquilli, Wm J., A. J. Paul, and K. S. Todd. "Assessment of toxicosis induced by high-dose administration of milbemycin oxime in Collies." American Journal of Veterinary Research 52, no. 7 (1991): 1170–72. http://dx.doi.org/10.2460/ajvr.1991.52.07.1170.

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Summary Fifteen Collies, previously having mild reactions to ivermectin challenge (120 μg/kg of body weight; 20 times the recommended dosage level), were studied to evaluate the effects of milbemycin oxime administration at 5 and 10 mg/kg (10 and 20 times the manufacturer's recommended dosage). Five replicates, comprising 3 dogs each, were formed on the basis of body weight. Within replicates, each dog was randomly allocated to treatment with 5 or 10 mg of milbemycin/kg or served as a untreated control. Dogs were examined repeatedly for signs of toxicosis for 4 days after treatment and daily t

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Conboy, Gary, Tonya Stewart, and Susan O'Brien. "Treatment of E. boehmi Infection in a Mixed-Breed Dog Using Milbemycin Oxime." Journal of the American Animal Hospital Association 49, no. 3 (2013): 204–9. http://dx.doi.org/10.5326/jaaha-ms-5832.

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Numerous bipolar plugged capillarid eggs were detected on a routine centrifugal fecal flotation examination of a 2 yr old castrated male boxer-Chinese shar pei mixed-breed. The eggs were identified as Eucoleus boehmi (E. boehmi), the nasal capillarid, based on size and shell wall surface morphology. The dog had a history of chronic sneezing (&gt; 5 times/day) and intermittent postexercise nasal discharge. Currently, there are no anthelmintics approved for use in dogs for the treatment of E. boehmi. Treatment of the dog with 0.5–1 mg/kg milbemycin oxime was ineffective, but treatment with 2

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Laidoudi, Younes, Hacène Medkour, Djamel Tahir, et al. "Field Evaluation of Preventive Efficacy of Monthly Multimodal Prophylactic Treatment (Milbactor® and Vectra® 3D) against Dirofilaria spp. in Dogs." Parasitologia 1, no. 3 (2021): 130–36. http://dx.doi.org/10.3390/parasitologia1030014.

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Dirofilaria immitis and Dirofilaria repens are mosquito-borne pathogens responsible for dirofilariasis in humans and animals. Their transmission and spread depend on the activity of vectors and the frequency of hosts in a given area. Here, we investigated the efficacy of a monthly multimodal prophylactic (MMP) strategy against canine dirofilariasis on Corsica Island (France). The study was conducted as evidence of an efficacy trial in which eighty dogs were divided into two groups: (i) one test group consisted of 25 dogs under the MMP [per-os administration of 1.5 tablets of milbemycin-oxime-p

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Book chapters on the topic "Milbemycin Oxime"

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Papich, Mark G. "Milbemycin Oxime." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00393-4.

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"Milbemycin-Oxime." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_1965.

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Papich, Mark G. "Milbemycin Oxime." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00359-9.

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Papich, Mark G. "Lufenuron Milbemycin Oxime." In Saunders Handbook of Veterinary Drugs. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-24485-5.00348-x.

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Papich, Mark G. "Lufenuron + Milbemycin Oxime." In Papich Handbook of Veterinary Drugs. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-323-70957-6.00312-5.

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Woodward, Kevin N. "GABAergic Neurotransmission and Toxicity 2: Macrocyclic Lactones." In Neurotransmitters and Toxicology. Royal Society of Chemistry, 2024. http://dx.doi.org/10.1039/9781839165795-00179.

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The term “macrocyclic lactones” refers to a group of drugs typified by the avermectins and milbemycins. The former group includes abamectin, ivermectin, eprinomectin, doramectin, selamectin and emamectin benzoate, while the latter group comprises moxidectin and milbemycin oxime. They are widely used as antiparasitic agents in veterinary medicine, but ivermectin has been widely used in humans for the prophylaxis and treatment of filariasis, onchocerciasis and loiasis, in addition to other parasitic conditions; while more recently, moxidectin has been authorized for the treatment of onchocercias

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Ovaert, Patricia, Marie Varloud, and Aurélie Lopez. "Comparative acceptance of two milbemycin oxime – praziquantel oral dewormers in dogs from different breeds." In BSAVA Congress Proceedings 2015. British Small Animal Veterinary Association, 2015. http://dx.doi.org/10.22233/9781910443521.63.1.

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Conference papers on the topic "Milbemycin Oxime"

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Xu, Qianqian, Jichang Li, Mingli Qu, Yaoteng Zhang, Xiaolei Yu, and Wensheng Xiang. "Acute Toxicity of Milbemycin Oxime in Mice." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5516689.

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Qu, Mingli, Jichang Li, and Wensheng Xiang. "Notice of Retraction: Mutagenic Action of Milbemycin oxime." In 2011 5th International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2011. http://dx.doi.org/10.1109/icbbe.2011.5781525.

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