Relevant bibliographies by topics / Mild Cognitive Impairment Alzheimer's disease

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Mild Cognitive Impairment Alzheimer's disease'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Kelley, Brendan J., and Ronald C. Petersen. "Alzheimer's Disease and Mild Cognitive Impairment." Neurologic Clinics 25, no. 3 (2007): 577–609. http://dx.doi.org/10.1016/j.ncl.2007.03.008.

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Masumi, Jafar, Fatemeh Fekar Gharamaleki, Neda Gilani, Maryam Noroozian, and Ahmad Reza Khatoonabadi. "Exploring language performance in people with mild cognitive impairment and Alzheimer's disease: a prospective longitudinal study." International Journal of Therapy and Rehabilitation 30, no. 12 (2023): 1–13. http://dx.doi.org/10.12968/ijtr.2022.0058.

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Background/Aims Language changes are the earliest signs and symptoms of mild cognitive impairment and Alzheimer's disease. The aim of this study was to explore the language difference performance between people with mild cognitive impairment, people with Alzheimer's disease and healthy individuals as a control group. To accomplish this aim, the language profile of both mild cognitive impairment and Alzheimer's disease needs to be characterised to determine which feature is more affected by both mild cognitive impairment and Alzheimer's disease among expressive language, receptive language, exe
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Zancada-Menéndez, Clara, Patricia Sampedro-Piquero, Azucena Begega, Laudino López, and Jorge Luis Arias. "Attention and inhibition in Mild Cognitive Impairment and Alzheimer's Disease." Escritos de Psicología - Psychological Writings 6, no. 3 (2013): 43–50. http://dx.doi.org/10.24310/espsiescpsi.v6i3.13288.

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Mild cognitive impairment is understood as a cognitive deficit of insufficient severity to fulfil the criteria for Alzheimer’s disease. Many studies have attempted to identify which cognitive functions are most affected by this type of impairment and which is the most sensitive neuropsychological test for early detection. This study investigated sustained and selective attention, processing speed, and the inhibition process using a sample of people divided into three groups mild cognitive impairment, Alzheimer disease and cognitively healthy controls selected and grouped based on their scores
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Forlenza, Orestes V., Breno S. Diniz, Leda L. Talib, et al. "Clinical and biological predictors of Alzheimer's disease in patients with amnestic mild cognitive impairment." Revista Brasileira de Psiquiatria 32, no. 3 (2010): 216–22. http://dx.doi.org/10.1590/s1516-44462010005000002.

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OBJECTIVE: To identify predictors of the progression from pre-dementia stages of cognitive impairment in Alzheimer's disease is relevant to clinical management and to substantiate the decision of prescribing antidementia drugs. METHOD: Longitudinal study of a cohort of elderly adults with amnestic mild cognitive impairment and healthy controls, carried out to estimate the risk and characterize predictors of the progression to Alzheimer's disease. RESULTS: Patients with amnestic mild cognitive impairment had a higher risk to develop Alzheimer's disease during follow-up (odds ratio = 4.5, CI95%
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Snowden, J. S. "MILD COGNITIVE IMPAIRMENT: AGING TO ALZHEIMER'S DISEASE." Brain 127, no. 1 (2004): 231—a—233. http://dx.doi.org/10.1093/brain/awh010.

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Petersen, Ronald C. "AGING, MILD COGNITIVE IMPAIRMENT, AND ALZHEIMER'S DISEASE." Neurologic Clinics 18, no. 4 (2000): 789–805. http://dx.doi.org/10.1016/s0733-8619(05)70226-7.

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Jellinger, K. A. "Mild Cognitive Impairment. Aging to Alzheimer's disease." European Journal of Neurology 10, no. 4 (2003): 466. http://dx.doi.org/10.1046/j.1468-1331.2003.00603_3.x.

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Chertkow, Howard. "Mild cognitive impairment: Aging to Alzheimer's disease." Annals of Neurology 55, no. 4 (2004): 600. http://dx.doi.org/10.1002/ana.20057.

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Appel, Jason, Elizabeth Potter, Qian Shen, et al. "A Comparative Analysis of Structural Brain MRI in the Diagnosis of Alzheimer’s Disease." Behavioural Neurology 21, no. 1-2 (2009): 13–19. http://dx.doi.org/10.1155/2009/103123.

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Dementia is a debilitating and life-altering disease which leads to both memory impairment and decline of normal executive functioning. While causes of dementia are numerous and varied, the leading cause among patients 60 years and older is Alzheimer’s disease. The gold standard for Alzheimer’s diagnosis remains histological identification of amyloid plaques and neurofibrillary tangles within the medial temporal lobe, more specifically the entorhinal cortex and hippocampus. Although no definitive cure for Alzheimer's disease currently exists, there are treatments targeted at preserving cogniti
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Zhou, Mengzhen. "The Relationship between Sleep Disturbance and Early Alzheimer's Disease – Mild Cognitive Impairment." Neuroscience and Neurological Surgery 14, no. 1 (2024): 01–06. http://dx.doi.org/10.31579/2578-8868/280.

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During sleep, the brain can clear toxins related to Alzheimer's disease. Compared with the baseline without sleep disorder, subjects with sleep disorder have a 1.49-fold increased risk of Alzheimer's disease. There is a two-way relationship between sleep/wakefulness disorder and Alzheimer's disease pathology. Sleep plays an important role in memory consolidation. Research shows that sleep disorder may have an important impact on the symptoms and course of Alzheimer's disease. Therefore, we need to better understand the mechanism of cognitive and behavioral impairment related to Alzheimer's dis
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Dissertations / Theses on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Netson, Kelli L. "Characterizing semantic memory in mild cognitive impairment." Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008p/netson.pdf.

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Thesis (Ph. D.)--University of Alabama at Birmingham, 2008.<br>Additional advisors: Paul D. Blanton, David G. Clark, Roy C. Martin, Virginia G. Wadley. Description based on contents viewed Feb. 9, 2009; title from PDF t.p. Includes bibliographical references (p. 63-76).
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Thompson, Juliann. "Sex Differences in Cognitive Decline in Mild Cognitive Impairment and Alzheimer's Disease." BYU ScholarsArchive, 2016. https://scholarsarchive.byu.edu/etd/6412.

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Alzheimer's disease (AD) is the most common form of dementia and results in progressive cognitive decline, particularly in regards to memory (National Institute on Aging, 2012). Prior research has shown sex differences in brain-atrophy rates of AD patients, with women experiencing a higher rate of progression in volume reduction (Skup et al., 2011). This suggests that there may also be differences in cognitive functioning between sexes, particularly in the rate of cognitive decline with a more rapid disease progression for dementing females compared to dementing males. The current study monito
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Khan, Wasim Nawaz. "Neuroimaging markers of Alzheimer's disease, mild cognitive impairment and normal healthy ageing." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/neuroimaging-markers-of-alzheimers-disease-mild-cognitive-impairment-and-normal-healthy-ageing(c507bdb2-721c-4060-8a06-9f01b39d3de1).html.

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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder clinically characterised by memory loss and cognitive decline that severely affect activities of daily living. Neuropathologically, the disease is characterised by two major proteinopathies, extracellular amyloid-beta (Aβ) plaques and intraneuronal neurofibrillary tangle pathology. The development of neuroimaging biomarkers for AD have transformed the assessment of brain changes associated with these pathological processes for the earlier detection of AD. However, additional work is needed to validate more robust neuroimaging
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Van, Adel J. Michael. "Prospective Memory Abilities In Aging and Mild Cognitive Impairment/ Early Alzheimer’s Disease." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35327.

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This dissertation describes separate but related studies that explore the prospective memory abilities of older adults and individuals with Mild Cognitive Impairment/Early Alzheimer’s disease. Prospective memory (PM) refers to the type of memory utilized to execute planned actions in accordance with a specific event. PM is critical to maintaining functional independence in older adults, as it can refer to such basic acts as remembering to turn off a stove or taking one’s medication. Research suggests PM abilities decline within normal aging and to a greater extent in Mild Cognitive Impairment
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Okello, Aren Atiti. "PET studies on disease progression and treatment efficacy in Alzheimer's disease and mild cognitive impairment." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/7110.

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Alzheimer’s disease (AD) is the most common cause of dementia. Mild cognitive impairment (MCI) is a transitional state between normal ageing and dementia. Positron emission tomography (PET) can detect the metabolic and neuro-chemical changes that occur in MCI and dementia. The aim of this thesis was to assess the use of PET as an in vivo biomarker for early disease detection, prognosis, and proof of treatment efficacy in AD and MCI. In study I, the prevalence of increased beta-amyloid deposition (assessed by 11C-PIB PET) and microglial activation (assessed by 11C-PK11195 PET) was studied in am
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Ramakers, Inez Hubertina Gertruda Bernard. "Prodromal Alzheimer's disease in subjects with Mild Cognitive Impairment predictive and diagnostic aspects." Maastricht : Maastricht : NeuroPsych Publishers ; University Library, Universiteit Maastricht [host], 2008. http://arno.unimaas.nl/show.cgi?fid=13926.

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Grönholm-Nyman, Petra. "Verbal learning in mild cognitive impairment and Alzheimer's disease : behavioural and neural approaches /." Åbo : Åbo Akademi University, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018662159&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Bush, Aryn L. H. "Effects of mild cognitive impairment on visual world recognition a longitudinal investigation /." Akron, OH : University of Akron, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1144771075.

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Dissertation (Ph. D.)--University of Akron, Dept. of Psychology, 2006.<br>"May, 2006." Title from electronic dissertation title page (viewed 09/16/2006) Advisor, Philip A. Allen; Committee members, Kevin P. Kaut, Martin D. Murphy, Raymond E. Sanders, Daniel L. Ely; Department Chair, Paul E. Levy; Dean of the College, Ronald F. Levant; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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Kalbe, Elke, Eric Salmon, Daniela Perani, et al. "Anosognosia in Very Mild Alzheimer’s Disease but Not in Mild Cognitive Impairment." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-135834.

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Objective: To study awareness of cognitive dysfunction in patients with very mild Alzheimer’s disease (AD) and subjects with mild cognitive impairment (MCI). Methods: A complaint interview covering 13 cognitive domains was administered to 82 AD and 79 MCI patients and their caregivers. The patient groups were comparable according to age and education, and Mini Mental State Examination (MMSE) scores were ≥24 in all cases. The discrepancy between the patients’ and caregivers’ estimations of impairments was taken as a measure of anosognosia. Results: Self-reports of cognitive difficulties were co
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Kalbe, Elke, Eric Salmon, Daniela Perani, et al. "Anosognosia in Very Mild Alzheimer’s Disease but Not in Mild Cognitive Impairment." Karger, 2005. https://tud.qucosa.de/id/qucosa%3A27681.

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Objective: To study awareness of cognitive dysfunction in patients with very mild Alzheimer’s disease (AD) and subjects with mild cognitive impairment (MCI). Methods: A complaint interview covering 13 cognitive domains was administered to 82 AD and 79 MCI patients and their caregivers. The patient groups were comparable according to age and education, and Mini Mental State Examination (MMSE) scores were ≥24 in all cases. The discrepancy between the patients’ and caregivers’ estimations of impairments was taken as a measure of anosognosia. Results: Self-reports of cognitive difficulties were co
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Books on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Burns, Jeffrey M. Mild cognitive impairment and early Alzheimer's disease: Detections and diagnosis. John Wiley & Sons, 2008.

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Holly, Tuokko, and Hultsch David F, eds. Mild cognitive impairment: International perspectives. Taylor & Francis, 2006.

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Burns, Jeffrey M. Early diagnosis and treatment of mild cognitive impairment. John Wiley & Sons, 2008.

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Burns, Jeffrey M. Early diagnosis and treatment of mild cognitive impairment. John Wiley & Sons, 2008.

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Lars-Olof, Wahlund, Erkinjuntti Timo, and Gauthier Serge 1950-, eds. Vascular cognitive impairment in clinical practice. Cambridge University Press, 2009.

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Morris, John, and Jeffrey Burns. Mild Cognitive Impairment. Wiley, 2007.

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Libon, David J., Melissa Lamar, Rodney A. Swenson, and Kenneth M. Heilman, eds. Vascular Disease, Alzheimer's Disease, and Mild Cognitive Impairment. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190634230.001.0001.

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Alzheimer’s disease and vascular dementia are acknowledged as the two most common types of dementia. Each of these dementia syndromes are associated with prodromal clinical syndromes, often referred to as mild cognitive impairment. Recent research has demonstrated considerable heterogeneity regarding the underlying neuropathology associated with these dementia syndromes and their prodromal disorders. Thus, it is often difficult to understand how or what underlying biological substrate is actually responsible for the alterations in neurocognition and behaviour as seen in clinical evaluations. T
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Kanow, Cora, and Ronald C. Petersen. Mild Cognitive Impairment: Aging to Alzheimer's Disease. Oxford University Press, 2003.

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Mild Cognitive Impairment: Aging to Alzheimer's Disease (Medicine). Oxford University Press, USA, 2003.

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Tuokko, Holly A., and David F. HULTSCH. Mild Cognitive Impairment. Taylor & Francis Group, 2020.

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Book chapters on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Richter, Brigitte Zoeller. "Mild Cognitive Impairment." In Alzheimer’s Disease. Humana Press, 2004. https://doi.org/10.1007/978-1-59259-661-4_16.

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Emilien, Gérard, Cécile Durlach, Kenneth Lloyd Minaker, Bengt Winblad, Serge Gauthier, and Jean-Marie Maloteaux. "Mild cognitive impairment." In Alzheimer Disease. Birkhäuser Basel, 2004. http://dx.doi.org/10.1007/978-3-0348-7842-5_7.

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Jones, David T., Marla B. Bruns, and Ronald C. Petersen. "Alzheimer's Disease and Mild Cognitive Impairment." In The Wiley Handbook on the Aging Mind and Brain. John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781118772034.ch21.

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Wolk, David, and Sanjeev Vaishnavi. "Mild cognitive impairment and Alzheimer's disease." In International Neurology. John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781118777329.ch39.

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Castro, Melissa, and Glenn E. Smith. "Mild cognitive impairment and Alzheimer's disease." In APA handbook of clinical geropsychology, Vol. 2: Assessment, treatment, and issues of later life. American Psychological Association, 2015. http://dx.doi.org/10.1037/14459-007.

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Jelic, Vesna, and Bengt Winblad. "Mild Cognitive Impairment." In Mapping the Progress of Alzheimer’s and Parkinson’s Disease. Springer US, 2002. http://dx.doi.org/10.1007/978-0-306-47593-1_29.

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Snyder, Charlene H., Bryan K. Woodruff, and Richard J. Caselli. "Cognitive disorders: mild cognitive impairment and Alzheimer's disease." In Evidence-Based Neurology: Management of Neurological Disorders. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781119067344.ch18.

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Mecocci, Patrizia, M. Cristina Polidori, and Domenico Praticó. "Antioxidant Clinical Trials in Mild Cognitive Impairment and Alzheimer’s Disease." In Studies on Alzheimer's Disease. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-598-9_16.

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Cummings, Jeffrey, and Kate Zhong. "Mild Cognitive Impairment and Prodromal Alzheimer’s Disease." In Neuro-Geriatrics. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56484-5_3.

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Riemer, Martin. "Time perception deficits in Alzheimer's disease and mild cognitive impairment." In Neural Bases of Timing and Time Perception. Routledge, 2024. https://doi.org/10.4324/9781003449546-8.

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Conference papers on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Bao, Sichen, Lifen Jiang, Qiantong Zhang, and Qian Gao. "VisionMamba-Based Multimodal Learning for Alzheimer's Disease and Mild Cognitive Impairment Diagnosis." In 2025 International Conference on Electrical Automation and Artificial Intelligence (ICEAAI). IEEE, 2025. https://doi.org/10.1109/iceaai64185.2025.10957211.

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Varghese, Bino, Shubham Gujar, Steven Yong Cen, et al. "Magnetic Resonance Imaging based Texture Analysis Predicts Conversion to Mild Cognitive Impairment and Alzheimer Disease." In 2024 20th International Symposium on Medical Information Processing and Analysis (SIPAIM). IEEE, 2024. https://doi.org/10.1109/sipaim62974.2024.10783512.

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Merlin, Silvia, Maira Oliveira, Luciana Cassimiro, et al. "FOLLOW UP OF THE PERSONALITY CHARACTERISTICS AND COGNITIVE EVOLUTION OF ELDERLY PEOPLE IN LONGITUDINAL FOLLOW-UP." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda068.

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Background: Some psychological and personality characteristics of individuals, seem to determine behavioral patterns that are associated with better health throughout life and, consequently, prevent the progression of early cognitive changes to dementia. Objective: Identify factors that interfere in the evolution of cognitive disorders. Methods: Volunteers were evaluated clinically and for personality characteristics and neuropsychological testing. Follow-up occurred over two years from the initial assessment, and participants’ cognitive categories were re-analyzed every six months to observe
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Dourado, Marcia, José Pedro Simões Neto, Gilberto Alves, and Cândida Alves. "FACIAL EXPRESSION RECOGNITION IN MILD AND MODERATE ALZHEIMER’S DISEASE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda006.

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Background: Facial expression recognition is essential for social cognition. Objectives: To compare facial expression recognition in mild and moderate Alzheimer’s disease (AD) and identify the cognitive and clinical factors associated with impairment according to disease severity. Methods: Participants with AD (n=52). FACES includes four subtasks: matching expressions with picture stimuli (tasks1and 2), labelling emotions (task 3) and recognizing emotional situations (task 4). Results: There were significant differences between groups in FACES global score, task 2 and task 4. In mild AD, FACES
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Lourenço, Rafael, and Marcio Balthazar. "CONECTOME COMPARISON IN MILD COGNITIVE IMPAIRMENT: AD CONTINUUM X SNAP." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda063.

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Background: Studies on functional magnetic resonance imaging of prodromal Alzheimer´s disease can help understanding on how it affects the brain. Objective: We seek for potential differences in brain resting state functional connectivity (FC) of subjects with Mild cognitive impairment with biomarkers: Alzheimer’s disease continuum (MCI-DA) and Suspected non-Alzheimer pathology (MCI-SNAP). Methods: MCI and controls were defined by the Clinical Dementia Rating, neuropsychological measures and cerebrospinal fluid data, resulting in 32 MCI-DA, 25 MCI-SNAP and 35 controls. An analysis ROI-to-ROI wa
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Almeida, Eliane Borca, Geise Silva, Isabella Avolio, et al. "INVESTIGATION OF EPISODIC MEMORY DEFCITS IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT (MCI)." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda043.

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Background: MCI can be classified as amnestic (aMCI) or non-amnestic (naMCI). Patients with aMCI are at increased risk of developing Alzheimer’s disease (AD). The clinical diagnosis encompasses episodic memory decline with preservation of activities of daily living, in addition to possible changes in other cognitive domains. Nevertheless, there is a lack of studies in the Brazilian population comparing the performance of aMCI on different episodic memory tests. Objectives: This study investigated episodic memory alterations in patients with aMCI and healthy controls (HC) through population-val
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Domashenko, Dmytro, Maksym Manko, Anton Popov, Igor Krashenyi, Javier Ramirez, and Juan Manuel Gorriz. "Feature ranking for mild cognitive impairment and Alzheimer's disease diagnosis." In 2017 Signal Processing Symposium (SPSympo). IEEE, 2017. http://dx.doi.org/10.1109/sps.2017.8053649.

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Silva, Geise, Isabella Avolio, Camila Dias, et al. "EXECUTIVE FUNCTION PERFORMANCE OF A BRAZILIAN SAMPLE OF MILD COGNITIVE IMPAIRMENT AND HEALTHY ELDERLY." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda035.

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Background: Mild cognitive impairment (MCI) is associated with cognitive alterations, usually related to memory, but can affect other domains such as executive functions (EFs), which are less explored in the literature. It is an intermediate condition between healthy aging and dementia and does not significantly affect an individual’s activities of daily living (ADL). Objectives: This study aimed to investigate executive function performance of a Brazilian sample of elderly people with multiple domains MCI (mdMCI) compared to healthy controls (HC) using EFs tasks. Methods: We included 54 subje
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Pinheiro, Mariana Maciel, Victor Albuquerque, Pedro Albuquerque, Eduardo Maranhão, Jonathan Diniz, and Breno Barbosa. "CORTICOBASAL SYNDROME DUE TO ALZHEIMER’S DISEASE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda055.

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Background: Corticobasal Syndrome (CBS) is a neurodegenerative syndrome that combines cortical and cognitive deficits secondary to different underlying pathological entities. Objectives: to report an early onset dementia case fulfilling criteria of probable CBS due to Alzheimer’s Disease (AD) based on biomarkers and neuroimaging. Methods: case report. Results: a 57-yearsold woman with college-level education and 18 months of cognitive decline. The first symptom was progressive inability to change gears in her car, followed by difficulties to get dressed, cognitive and motor complaints. Neurolo
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Leirer, V. M., F. Glöckner, T. Elbert, and I. T. Kolassa. "An auditory computer-based training for mild cognitive impairment and mild Alzheimer's disease." In the 2nd International Conference. ACM Press, 2009. http://dx.doi.org/10.1145/1579114.1579168.

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Reports on the topic "Mild Cognitive Impairment Alzheimer's disease"

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Fillipin, Federico, Pamela Seron, and Ruvistay Gutierrez-Arias. Effectiveness of antihypertensive drugs to prevent cognitive decline, mild cognitive impairment, and dementia. An overview of systematic reviews. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.12.0057.

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Review question / Objective: To determine effectiveness of antihypertensive drugs to prevent different dementia subtypes such as Alzheimer’s disease and vascular dementia. Condition being studied: Dementia is a global health burden, with the number of affected individuals increasing. A recent meta-analysis reported that the prevalence of all-type dementia was 697 per 10,000 people and the prevalence of Alzheimer’s disease was 324 per 10,000 people. The SHEP and SYST-EUR were the two first randomized controlled trials to show that hypertension treatment reduces dementia risk.
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Catana, Cristina-Sorina, Monica-Mihaela Marta, Mădălina Valeanu, Lucia Dican, and Catalina Angela Crisan. HLA and microRNAs as key orchestrators of mild cognitive impairment and Alzheimer’s disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.7.0045.

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Long, Cong, XUke Han, Yunjiao Yang, Tongyi Li, Qian Zhou, and Qiu Chen. Efficacy of Intranasal Insulin in Improving Cognition in Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0054.

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Review question / Objective: How does the efficacy of Intranasal Insulin in improving Cognition in Mild Cognitive Impairment or Dementia. Condition being studied: Insulin regulates many aspects of brain function related to mild cognitive impairment (MCI) or dementia, which can be delivered to the brain center via intranasal (IN) devices. Some small, single-site studies indicated that intranasal insulin can enhance memory in patients with MCI or dementia. The pathophysiology of Alzheimer disease (AD) and diabetes mellitus (DM) overlap, making insulin an attractive therapy for people suffering f
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Liu, Boyu, Wenyue Sun, and Qing Zhao. The efficacy of hypoglycemic agents for alzheimer’s disease and mild cognitive Impairment: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.6.0075.

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Ma, Yunxing, Julia Brettschneider, and Joanna Collingwood. A systematic review and meta-analysis of cerebrospinal fluid amyloid and tau levels in patients progressing from Mild Cognitive Impairment to Alzheimer’s Disease. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.7.0020.

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Abstract:
Review question / Objective: Reported levels of amyloid-beta and tau in human cerebrospinal fluid (CSF) are evaluated to discover if these biochemical markers can predict the transition from Mild Cognitive Impairment (MCI) to Alzheimer’s disease (AD). A systematic review and quantitative meta-analyses are performed to test relationships between three potential biomarkers in CSF (Aβ(1-42), T-tau, and P-tau181) and the evolution of AD in longitudinal evaluations of levels relative to baseline, using prior-published experimental data. The primary focus of the analysis is on the period describing
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