Academic literature on the topic 'Mineralized differentiation'

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Journal articles on the topic "Mineralized differentiation"

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Adekeye, J. I. D., and A. D. Adedoyin. "ECONOMIC POTENTIALS OF THE PEGMATITES OF ERUKU AREA, SOUTHWESTERN NIGERIA." Continental J. Earth Sciences 2 (November 7, 2007): 1–6. https://doi.org/10.5281/zenodo.824279.

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The close proximity of the pegmatites of Eruku area to the strongly mineralized pegmatites of Egbe area and lack of published work on those from the former formed the basis of this research. Sub-parallel, steeply-dipping, lenticular/podlike pegmatite bodies occur in the Eruku area, southwestern Nigeria. They are emplaced within the late Proterozoic to early Paleozoic crystalline basement complex rocks. Some of these pegmatites are mineralized while others are barren. The barren pegmatites are sources of industrial minerals like feldspar and quartz. The mineralized pegmatites are also sources o
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Liu, Wei, Xiaowei Jing, Zhiwen Xu, and Chong Teng. "PEGDA/HA mineralized hydrogel loaded with Exendin4 promotes bone regeneration in rat models with bone defects by inducing osteogenesis." Journal of Biomaterials Applications 35, no. 10 (2021): 1337–46. http://dx.doi.org/10.1177/0885328220987046.

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Scaffolds with osteogenic differentiation function play an important role in the healing process of bone defects. Here, we designed a high strength Poly(ethyleneglycol) diacrylate/Hydroxyapatite (PEGDA/HA) mineralized hydrogel loaded with Exendin4 for inducing osteogenic differentiation. In this study, PEGDA hydrogel was prepared by photo initiating method. PEGDA/HA mineralized hydrogel was prepared by in-situ precipitation method, and Exendin4 was loaded by gel adsorption. The effects of different calcium and phosphorus concentrations on the strength and Exendin4 release of PEGDA/HA hydrogels
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Dewey, Marley J., Eileen M. Johnson, Simona T. Slater, Derek J. Milner, Matthew B. Wheeler, and Brendan A. C. Harley. "Mineralized collagen scaffolds fabricated with amniotic membrane matrix increase osteogenesis under inflammatory conditions." Regenerative Biomaterials 7, no. 3 (2020): 247–58. http://dx.doi.org/10.1093/rb/rbaa005.

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Abstract Defects in craniofacial bones occur congenitally, after high-energy impacts, and during the course of treatment for stroke and cancer. These injuries are difficult to heal due to the overwhelming size of the injury area and the inflammatory environment surrounding the injury. Significant inflammatory response after injury may greatly inhibit regenerative healing. We have developed mineralized collagen scaffolds that can induce osteogenic differentiation and matrix biosynthesis in the absence of osteogenic media or supplemental proteins. The amniotic membrane is derived from placentas
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Eren, E. Deniz, Gulistan Tansik, Ayse B. Tekinay, and Mustafa O. Guler. "Mineralized Peptide Nanofiber Gels for Enhanced Osteogenic Differentiation." ChemNanoMat 4, no. 8 (2018): 837–45. http://dx.doi.org/10.1002/cnma.201700354.

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Liu, Yangxi, Jue Hu, and Hongli Sun. "Mineralized nanofibrous scaffold promotes phenamil‐induced osteoblastic differentiation while mitigating adipogenic differentiation." Journal of Tissue Engineering and Regenerative Medicine 14, no. 3 (2020): 464–74. http://dx.doi.org/10.1002/term.3007.

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Bjørge, Isabel M., Insung S. Choi, Clara R. Correia, and João F. Mano. "Nanogrooved microdiscs for bottom-up modulation of osteogenic differentiation." Nanoscale 11, no. 35 (2019): 16214–21. http://dx.doi.org/10.1039/c9nr06267j.

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Novel disc-like microparticles, herein termed as “topodiscs”, with grooved surface nanotopography effectively enhanced cell culture and allowed for a bottom-up engineering of 3D mineralized microtissues.
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Ren, Xiaoyan, Qi Zhou, David Foulad, et al. "Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds." Science Advances 5, no. 6 (2019): eaaw4991. http://dx.doi.org/10.1126/sciadv.aaw4991.

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The instructive capabilities of extracellular matrix–inspired materials for osteoprogenitor differentiation have sparked interest in understanding modulation of other cell types within the bone regenerative microenvironment. We previously demonstrated that nanoparticulate mineralized collagen glycosaminoglycan (MC-GAG) scaffolds efficiently induced osteoprogenitor differentiation and bone healing. In this work, we combined adenovirus-mediated delivery of osteoprotegerin (AdOPG), an endogenous anti-osteoclastogenic decoy receptor, in primary human mesenchymal stem cells (hMSCs) with MC-GAG to u
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Park, Kyung-Ran, Joon Yeop Lee, Myounglae Cho, Jin Tae Hong, and Hyung-Mun Yun. "Biological Mechanisms of Paeonoside in the Differentiation of Pre-Osteoblasts and the Formation of Mineralized Nodules." International Journal of Molecular Sciences 22, no. 13 (2021): 6899. http://dx.doi.org/10.3390/ijms22136899.

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Paeonia suffruticosa is a magnificent and long-lived woody plant that has traditionally been used to treat various diseases including inflammatory, neurological, cancer, and cardiovascular diseases. In the present study, we demonstrated the biological mechanisms of paeonoside (PASI) isolated from the dried roots of P. suffruticosa in pre-osteoblasts. Herein, we found that PASI has no cytotoxic effects on pre-osteoblasts. Migration assay showed that PASI promoted wound healing and transmigration in osteoblast differentiation. PASI increased early osteoblast differentiation and mineralized nodul
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Weisgerber, Daniel W., Steven R. Caliari, and Brendan A. C. Harley. "Mineralized collagen scaffolds induce hMSC osteogenesis and matrix remodeling." Biomaterials Science 3, no. 3 (2015): 533–42. http://dx.doi.org/10.1039/c4bm00397g.

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Incorporating calcium phosphate nanocrystallites into a collagen biomaterial promotes mesenchymal stem cell (MSC) osteogenic differentiation in the absence of conventional growth factor supplements. Mineralized collagen scaffolds also support MSC proliferation and new matrix biosynthesis.
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Apel, Christian, Patricia Buttler, Jochen Salber, Anandhan Dhanasingh, and Sabine Neuss. "Differential mineralization of human dental pulp stem cells on diverse polymers." Biomedical Engineering / Biomedizinische Technik 63, no. 3 (2018): 261–69. http://dx.doi.org/10.1515/bmt-2016-0141.

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Abstract In tissue engineering, biomaterials are used as scaffolds for spatial distribution of specific cell types. Biomaterials can potentially influence cell proliferation and extracellular matrix formation, both in positive and negative ways. The aim of the present study was to investigate and compare mineralized matrix production of human dental pulp stem cells (DPSC), cultured on 17 different well-characterized polymers. Osteogenic differentiation of DPSC was induced for 21 days on biomaterials using dexamethasone, L-ascorbic-acid-2-phosphate, and sodium β-glycerophosphate. Success of dif
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Book chapters on the topic "Mineralized differentiation"

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Martins, Ana M., Catarina M. Alves, Rui L. Reis, Antonios G. Mikos, and F. Kurtis Kasper. "Toward Osteogenic Differentiation of Marrow Stromal Cells and In Vitro Production of Mineralized Extracellular Matrix onto Natural Scaffolds." In Biological Interactions on Materials Surfaces. Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-98161-1_13.

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Karaman, Ozan. "Mineralized Nanofibers for Bone Tissue Engineering." In Biomedical Engineering. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-3158-6.ch020.

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The limitation of orthopedic fractures and large bone defects treatments has brought the focus on fabricating bone grafts that could enhance ostegenesis and vascularization in-vitro. Developing biomimetic materials such as mineralized nanofibers that can provide three-dimensional templates of the natural bone extracellular-matrix is one of the most promising alternative for bone regeneration. Understanding the interactions between the structure of the scaffolds and cells and therefore the control cellular pathways are critical for developing functional bone grafts. In order to enhance bone reg
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Karaman, Ozan. "Mineralized Nanofibers for Bone Tissue Engineering." In Advancing Medicine through Nanotechnology and Nanomechanics Applications. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1043-7.ch009.

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The limitation of orthopedic fractures and large bone defects treatments has brought the focus on fabricating bone grafts that could enhance ostegenesis and vascularization in-vitro. Developing biomimetic materials such as mineralized nanofibers that can provide three-dimensional templates of the natural bone extracellular-matrix is one of the most promising alternative for bone regeneration. Understanding the interactions between the structure of the scaffolds and cells and therefore the control cellular pathways are critical for developing functional bone grafts. In order to enhance bone reg
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Suresh, Nandita, Betsy Joseph, Tuomas Waltimo, and Sukumaran Anil. "Phyto-Nanoparticles in Osteogenesis." In Innovation in Osteogenesis Research [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.1005422.

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Phyto-nanoparticles derived from plants are an emerging class of nanomaterials that integrate the versatility of nanotechnology with the therapeutic potential of botanical ingredients. This chapter explores the utility of phyto-nanoparticles in stimulating osteogenesis for applications in bone tissue engineering and regeneration. Plant extracts serve as sustainable nanoparticle building blocks or coatings through green synthesis approaches. Resultant phyto-nanoparticles possess multifunctional capabilities stemming from the bioactive phytochemical components that enable the modulation of osteo
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Man G.C.W., Yeung Y.H., Wang W.J., et al. "The Effect of Melatonin on Proliferation and Differentiation of Osteoblasts in Adolescent Idiopathic Scoliosis Vs Normal Control." In Studies in Health Technology and Informatics. IOS Press, 2008. https://doi.org/10.3233/978-1-58603-888-5-373.

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Low BMD and dysfunction of melatonin signaling pathway has been suggested as the possible key link to the spinal deformity in AIS. Prior studies shown that melatonin can influence and regulate skeletal growth and bone formation in human and animal models. However, there is a relative lack of direct evidence on the role of melatonin on AIS at the cellular and molecular level. To investigate the effect of melatonin on AIS osteoblasts at the cellular level. In vitro assays were performed with osteoblasts isolated from 7 girls with severe AIS and 7 controls. These were treated with different conce
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Lowenstam, Heinz A., and Stephen Weiner. "Biomineralization Processes." In On Biomineralization. Oxford University Press, 1989. http://dx.doi.org/10.1093/oso/9780195049770.003.0005.

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The large number of different minerals formed by organisms from almost 50 different phyla described in Chapter 2 should in itself discourage anyone from searching for the mechanism of biomineralization. On the other hand, the survey of macromolecules used by many organisms to control mineralization (Chapter 2), even though limited primarily to carbonate- and phosphate-bearing mineralized hard parts, shows that similar and rather unusual acidic glycoproteins and proteoglycans are widely utilized in biomineralization. This raises the possibility that many organisms may have adopted common approa
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Vernejoul, Marie-Christine de, and Pierre J. Marie. "New aspects of bone biology." In The Spectrum of Renal Osteodystrophy. Oxford University PressNew York, NY, 2001. http://dx.doi.org/10.1093/oso/9780192632302.003.0001.

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Abstract Bone is formed of an abundant calcified extracellular matrix. This tissue serves three main functions: mechanical, protective for the vital organs, and metabolic as a reserve of ions, especially calcium and phosphorus. Bone tissue undergoes continual renewal in order to maintain the mechanical competence of the bone matrix. This remodeling is performed by two cell types: osteoclasts which resorb calcified matrix and osteoblasts which synthesize new bone matrix. Both cell types interact during bone remodeling, a process that allows continuous renewal of the bone matrix. In adult human
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Conference papers on the topic "Mineralized differentiation"

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Tsiklauri, Lali, Janina Werner, Klaus Frommer, et al. "FRI0525 DURING ADIPOGENIC DIFFERENTIATION OF MSC ON MINERALIZED BONE FRAGMENTS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.4328.

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Reports on the topic "Mineralized differentiation"

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Azadbakht, Z., D. R. Lentz, and C. R. M. McFarlane. Using biotite composition of the Devonian Mount Elizabeth Intrusive Complex, New Brunswick, as a proxy for magma fertility and differentiation in W-Mo-Au-Sb mineralized magmatic hydrothermal systems. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2015. http://dx.doi.org/10.4095/296488.

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