Academic literature on the topic 'Minnie Mouse'

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Journal articles on the topic "Minnie Mouse"

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Lavitt, Melissa R. "From Pippi Longstockings to Minnie Mouse: Reexamining Theories of Female Development." Journal of Baccalaureate Social Work 3, no. 1 (October 1, 1997): 17–30. http://dx.doi.org/10.18084/1084-7219.3.1.17.

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An awareness of the influence of sexism on the lives of women is typically evident in social work teaching and practice. The growth of scholarship on female psychological development makes fostering this awareness easier. This paper cautions against wholesale incorporation of the research findings on adolescent girls into the classroom or agency. Without such consideration, we are in danger of pathologizing female experience at adolescence, ignoring the concerns of younger girls, and decontextualizing human development. The feisty, self-assured nineyear-old Pippi Longstockings may not be an accurate picture just as the tentative 16-year-old Minnie Mouse may be limited in its generalizability. One must be cautious in claiming to discover yet another female problem. This paper summarizes and critically analyzes the current body of research; philosophical, theoretical and methodological concerns are described. Finally, recommendations for using the research in this area are outlined.
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Álvarez-Carrión, Luis, Irene Gutiérrez-Rojas, María Rosario Rodríguez-Ramos, Juan A. Ardura, and Verónica Alonso. "MINDIN Exerts Protumorigenic Actions on Primary Prostate Tumors via Downregulation of the Scaffold Protein NHERF-1." Cancers 13, no. 3 (January 24, 2021): 436. http://dx.doi.org/10.3390/cancers13030436.

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Advanced prostate cancer preferential metastasis to bone is associated with osteomimicry. MINDIN is a secreted matrix protein upregulated in prostate tumors that overexpresses bone-related genes during prostate cancer progression. Na+/H+ exchanger regulatory factor (NHERF-1) is a scaffold protein that has been involved both in tumor regulation and osteogenesis. We hypothesize that NHERF-1 modulation is a mechanism used by MINDIN to promote prostate cancer progression. We analyzed the expression of NHERF-1 and MINDIN in human prostate samples and in a premetastatic prostate cancer mouse model, based on the implantation of prostate adenocarcinoma TRAMP-C1 (transgenic adenocarcinoma of the mouse prostate) cells in immunocompetent C57BL/6 mice. The relationship between NHERF-1 and MINDIN and their effects on cell proliferation, migration, survival and osteomimicry were evaluated. Upregulation of MINDIN and downregulation of NHERF-1 expression were observed both in human prostate cancer samples and in the TRAMP-C1 model. MINDIN silencing restored NHERF-1 expression to control levels in the mouse model. Stimulation with MINDIN reduced NHERF-1 expression and triggered its mobilization from the plasma membrane to the cytoplasm in TRAMP-C1 cells. MINDIN-dependent downregulation of NHERF-1 promoted tumor cell migration and proliferation without affecting osteomimicry and adhesion. We propose that MINDIN downregulates NHERF-1 expression leading to promotion of processes involved in prostate cancer progression.
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Rambaruth, Neela, Sabine Jégouzo, Hayley Marlor, Maureen Taylor, and Kurt Drickamer. "Mouse Mincle: Characterization as a Model for Human Mincle and Evolutionary Implications." Molecules 20, no. 4 (April 15, 2015): 6670–82. http://dx.doi.org/10.3390/molecules20046670.

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van der Peet, Phillip L., Christian Gunawan, Shota Torigoe, Sho Yamasaki, and Spencer J. Williams. "Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle." Chemical Communications 51, no. 24 (2015): 5100–5103. http://dx.doi.org/10.1039/c5cc00085h.

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Glucose monocorynomycolate is revealed to signal through both mouse and human Mincle. Glycerol monocorynomycolate is shown to selectively signal through human Mincle, with the activity residing predominantly in the 2′S-isomer.
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Shah, Sayali, Masahiro Nagata, Sho Yamasaki, and Spencer J. Williams. "Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle." Chemical Communications 52, no. 72 (2016): 10902–5. http://dx.doi.org/10.1039/c6cc05631h.

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Ardura, Juan A., Irene Gutiérrez-Rojas, Luis Álvarez-Carrión, M. Rosario Rodríguez-Ramos, José M. Pozuelo, and Verónica Alonso. "The secreted matrix protein mindin increases prostate tumor progression and tumor-bone crosstalk via ERK 1/2 regulation." Carcinogenesis 40, no. 7 (June 5, 2019): 828–39. http://dx.doi.org/10.1093/carcin/bgz105.

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Abstract Advanced prostate cancer cells preferentially metastasize to bone by acquiring a bone phenotype that allows metastatic cells to thrive in the skeletal environment. Identification of factors that promote the expression of ectopic bone genes—process known as osteomimicry—leading to tumor progression is crucial to prevent and treat metastatic prostate cancer and prolong life expectancy for patients. Here, we identify the extracelular matrix protein mindin in the secretome of prostate adenocarcinoma cells and show that mindin overexpression in human and mouse TRAMP-C1-induced prostate tumors correlates with upregulated levels of bone-related genes in the tumorigenic prostate tissues. Moreover, mindin silencing decreased osteomimicry in adenocarcinoma cells and in the prostate tumor mice model, as well as reduced tumor cell proliferation, migration and adhesion to bone cells. Inhibition of the extracellular signal-regulated kinase 1/2 (ERK 1/2) phosphorylation decreased the proliferative, migratory and pro-adhesion actions of mindin on prostate tumor cells. In addition, conditioned media obtained by crosstalk stimulation of either osteocytes or osteoblasts with the secretome of TRAMP-C1 cells promoted osteomimicry in prostate tumor cells; an effect inhibited by mindin silencing of TRAMP-C1 cells. In vivo, tibiae of primary tumor-bearing mice overexpressed the pro-angiogenic and pro-metastattic factor vascular endothelial growth factor receptor 2 (VEGFR2) in a mindin-dependent manner. Our findings indicate that mindin is a novel regulator of osteomimicry in prostate tumors and potentially mediates tumor-bone cell crosstalk, suggesting its promising role as a target to inhibit bone metastases.
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Bugarcic, A., K. Hitchens, A. G. Beckhouse, C. A. Wells, R. B. Ashman, and H. Blanchard. "Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans." Glycobiology 18, no. 9 (June 25, 2008): 679–85. http://dx.doi.org/10.1093/glycob/cwn046.

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Carlson, David R. "Essays on Ricardian Literature in Honour of J. A. Burrow by A.J. Minnis, Charlotte C. Morse and Thorlac Turville-Petre." Arthuriana 9, no. 1 (1999): 155–57. http://dx.doi.org/10.1353/art.1999.0025.

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Hattori, Yuki, Daisuke Morita, Nagatoshi Fujiwara, Daiki Mori, Takashi Nakamura, Hideyoshi Harashima, Sho Yamasaki, and Masahiko Sugita. "Glycerol Monomycolate Is a Novel Ligand for the Human, but Not Mouse Macrophage Inducible C-type Lectin, Mincle." Journal of Biological Chemistry 289, no. 22 (April 13, 2014): 15405–12. http://dx.doi.org/10.1074/jbc.m114.566489.

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Kerscher, Bernhard, Gillian J. Wilson, Delyth M. Reid, Daiki Mori, Julie A. Taylor, Gurdyal S. Besra, Sho Yamasaki, Janet A. Willment, and Gordon D. Brown. "Mycobacterial receptor, Clec4d (CLECSF8, MCL), is coregulated with Mincle and upregulated on mouse myeloid cells following microbial challenge." European Journal of Immunology 46, no. 2 (December 8, 2015): 381–89. http://dx.doi.org/10.1002/eji.201545858.

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Dissertations / Theses on the topic "Minnie Mouse"

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Janus, Lydia Maria. "Transmission of minute virus of mice in mouse populations international PhD program "infection biology"." Giessen DVG-Service, 2009. http://d-nb.info/995700702/04.

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Luud, Aarne. "Evaluation of moose habitats and forest reclamation in Estonian oil shale mining areas /." Online version, 2006. http://dspace.utlib.ee/dspace/bitstream/10062/684/5/luudaarne.pdf.

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Misyak, Sarah A. "Development of a SNP Assay for the Differentiation of Allelic Variations in the mdx Dystrophic Mouse Model." Thesis, Virginia Tech, 2008. http://hdl.handle.net/10919/32325.

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The purpose of this study was to develop a SNaPshot® assay to simultaneously discriminate between the dystrophic and wild type (wt) alleles in mdx mice. The mdx mouse is an animal model for Duchenne muscular dystrophy (DMD), a severe and fatal muscle wasting disease. To evaluate possible treatments and to carry out genetic studies, it is essential to distinguish between mice that carry the mutant dystrophic or wt allele(s). The current Amplification-Resistant Mutation System (ARMS) assay used to genotype mdx mice is labor intensive and sometimes fails to yield typing results, which reduce its efficiency as a screening tool. An alternative assay based on single nucleotide polymorphism (SNP) extension technology (i.e., SNaPshot®) would be advantageous because its specificity and capability to be automated would reduce the labor involved and increase the fidelity of each assay. A SNaPshot® assay has been developed that provides a robust and potentially automatable assay that discriminates between the wt and dystrophic alleles. The assay has been optimized to use: an undiluted DNA in the PCR, a 0.1 µM PCR primer concentration, a full PCR product for the SNP extension reaction, a 50ºC annealing temperature for the SNP extension in accordance with standard SNaPshot® conditions, and a 0.4 µM concentration of the SNP extension primer. The advantages of the resultant SNaPshot® assay over the ARMS assay include higher fidelity, robustness, and more consistent performance within and among laboratories, and reduced risk of human error.
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Leighty, Ralph E. "Statistical and Data Mining Methodologies for Behavioral Analysis in Transgenic Mouse Models of Alzheimer’s Disease: Parallels with Human AD Evaluation." Scholar Commons, 2009. http://scholarcommons.usf.edu/etd/3872.

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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of human senile dementia. Alzheimer’s represents a significant public health concern, having widespread social and economic implications. Consequently, protocols for early detection and therapeutic intervention (both behavioral and pharmacologic) constitute important targets for medical investigation. Furthermore, contemporary research depends upon comprehensive neurobehavioral assessment and advanced statistical and computational analytic methodologies for characterizing AD-associated sensorimotor and cognitive impairment, as well as evaluating therapeutic efficacy. This dissertation introduces data mining-based techniques (decision trees, neural networks, support vector machines) for behavioral analysis in both nontransgenic and Alzheimer’s transgenic mice, to evaluate the cognitive benefits of long-term caffeine treatment. Both treatment and transgenic effects are identified through advanced statistical (discriminant analysis) and data mining approaches. In addition, a novel mouse-based cognitive assessment paradigm, adapted from a human interference learning AD-diagnostic protocol, is implemented to evaluate both genetic (GRK5) and therapeutic (GM-CSF) effects in mice, against an Alzheimer’s transgenic background. Data mining techniques are shown to be comparable to con ventional statistical analyses, often providing complementary diagnostic information. Indeed, comparisons between data mining-based and multivariate statistical analyses, with respect to groupwise discriminability, support the use of both methodologies in neurobehavioral research. Future work involving both data mining-based and multivariate statistical analyses of cognitive-behavioral data is discussed, emphasizing the need for longitudinal studies, repeated-measure designs, and spatiotemporal modeling for evaluating the time-course of both human AD and AD-like pathology in transgenic mouse models.
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Leighty, Ralph E. "Statistical and data mining methodologies for behavioral analysis in transgenic mouse models of Alzheimer's disease : parallels with human AD evaluation." [Tampa, Fla] : University of South Florida, 2009. http://purl.fcla.edu/usf/dc/et/SFE0002869.

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Silvain, Jean-François. "Etude microstructurale de materiaux magnetiques durs et mous, de silicium polycristallin." Poitiers, 1987. http://www.theses.fr/1987POIT2295.

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Contribution a la connaissance des materiaux magnetiques durs et mous grace a des mesures magnetiques et l'etude des microstructures par microscopie electronique. Etude de couches "dures" de co-ni et de co-fe en fonction de la nature des substrats, de l'epaisseur des films et de l'angle d'incidence utilise. Etude du grenat en liaison avec son utilisation pour les memoires a bulles magnetiques. Influence de l'implantation ionique sur la structure cristalline des grenats
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Bodart, Vincent. "Controle de la croissance d'empilements ultra-minces carbone tungstene et silicium-tungstene par ellipsometrie cinetique in-situ : application aux miroirs pour x-mous." Paris 7, 1987. http://www.theses.fr/1987PA077094.

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Dans le but d'obtenir des reflecteurs de bragg pour rx mous, on realise par pulverisation avec controle ellipsometrique in situ des empilements de 200 couches nanometriques. Observation de la formation des interfaces a l'echelle atomique, evaluation des rugosites d'interface
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Abderrahim, Abdelkrim. "Utilisation d'un mini-pressiomètre pour la mesure directe du frotttement [i. E. Frottement] à l'interface sol pulvérulent-inclusion." Vandoeuvre-les-Nancy, INPL, 1991. http://www.theses.fr/1991INPL058N.

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Dans le but d'un dimensionnement efficace des inclusions dans des sols pulvérulents, on a visé principalement par notre travail, les paramètres susceptibles de jouer un rôle sur le frottement mobilisé à l'interface sables-inclusions. A partir d'une étude préliminaire, Propriétés physiques et mécaniques classiques au laboratoire et Propriétés pressiométriques au laboratoire, nous avons pu : 1) d'une part identifier et d'autre part déterminer les propriétés mécaniques que ce soit à l'aide des appareils classiques au laboratoire (Triaxial, boite de Casagrande et boite de cisaillement annulaire) ou bien à l'aide d'un mini-pressiomètre de nos deux sables ; 2) déterminer la marche à suivre pour la réalisation de la phase préparatoire des essais de notre nouvelle approche (mise en place de l'échantillon, mise en place de la sonde mini-pressiométrique et éventuellement l'application d'une contrainte verticale). Pour le comportement à l'interface sable-structure, une étude classique au laboratoire approche classique au laboratoire nous a permis de démasquer le rôle de certains paramètres influençant le frottement mobilisé à l'interface. Les résultats de cette étude ont été comparés avec ceux de notre nouvelle approche pour mettre en évidence l'effet tridimensionnel et l'effet du mode de mise en place de l'inclusion. Durant cette nouvelle approche, l'utilisation d'un mini-pressiomètre dans le dispositif expérimental nous a permis de connaitre d'une façon précise la contrainte normale à l'interface et de la contrôler pendant le cisaillement. En plus le rôle de la densité, de la rugosité et de la minéralogie qui sont démasquées à l'aide des deux études principales, notre étude comparative nous a permis de conclure que le frottement mobilisé par la sonde mini-pressiomètrique se situe entre celui de la boite de cisaillement (maximal) et celui de l'appareil Bromhead (résiduel), il est plus proche du frottement résiduel mobilisé à l'interface
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Younes, Mahmoud. "Modelisation d'un element de structure composite a noyau leger gaine." Paris, ENSAM, 1986. http://www.theses.fr/1986ENAM0003.

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Dans le cadre de la conception d'engins de recherche et d'exploitation en mer, profonde, nous nous interessons aux poutres composites a noyau leger gaine. Le noyau est constitue d'une mousse syntactique. La gaine est une enveloppe composite stratifiee. Cette etude comprend principalement deux grandes parties; une modelisation theorique et une analyse experimentale. La partie theorique est basee sur les hypotheses de navier-bernouilli pour les problemes de flexion et celles de vlassov pour les problemes de torsion et prend en compte les deformations de cisaillement introduites en valeurs moyennes entre deux sections droites voisines. Ce modele assure egalement la continuite des deplacements entre le noyau et la gaine. Nous modelisons un element "p. C. N. L. G" et nous introduisons les conditions aux limites, notamment des forces de liaison aux noeuds de cet element pour etablir la relation matricielle de comportement par l'application du principe des puissances virtuelles. L'analyse experimentale a pour objet de caracteriser les materiaux constituant la structure et de qualifier sur des modeles dits de "validation" le modele theorique dont on vient de definir les grandes lignes. L'element "p. C. N. L. G" permet d'analyser les structures en lignes ou des structures spatiales, necessitant neanmoins et ulterieurement la realisation d'un element de junction assurant l'assemblage des elements poutres. Les applications de cette etude peuvent etre developpees dans la conception des flotteurs, des tubes, des engins, etc. . .
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Ruterana, Pierre. "Structure des interfaces, etude par microscopie electronique en transmission, application : materiaux semiconduteurs iii-v et multicouches pour optiques dans le domaine des rayons x mous." Caen, 1987. http://www.theses.fr/1987CAEN2032.

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Nous avons surtout utilise le mode "haute resolution" sur un microscope a 200kv. La resolution obtenue etait de 2. 4 a. La technique de peparation d'echantillons que nous avons mise au point pour l'etude du procede de passivation (si::(3)n::(4)/gaas) nous a permis de caracteriser dans de tres bonnes conditions les multicouches pour rayons x mous et les heterostructures de croissance epitaxiale. Ce travail fut un suivi des procedes en conjugaison avec d'autres techniques de caracterisation. La comparaison des resultats de ces diverses techniques nous a permis d'apprehender la chimie et la physique des interfaces dans les materiaux etudies
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Books on the topic "Minnie Mouse"

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Lowe, Gemma Louise, Jim Willmott, and Jack Aylward. Minnie Mouse bow-tique. Bath: Parragon, 2012.

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), Disney Enterprises (1996, ed. Minnie Mouse: Pretty in pink. Franklin, TN: Dalmatian Press, 2012.

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Bottini, Clara. La depressión de Minnie Mouse: Novela. Buenos Aires: Torres Agüero Editor, 1989.

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Joanne, Schmaltz, ed. The Minnie & friends cookbook. New York: Disney Press, 2014.

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Calder, Lyn. Walt Disney's Minnie Mouse and the friendship lockets. Racine, Wis: Western Pub. Co., 1993.

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Sapienza, Marilyn J. Baby Minnie, come and play: A book about association. [California?]: Walt Disney Co., 1990.

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Scollon, Bill. Minnie's summer vacation. New York: Disney Press, 2014.

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Inc, Loter, ed. Minnie's Bow-tique. New York: Disney Press, 2009.

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Ring, Susan. Minnie's summer vacation. New York: Disney Press, 2009.

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Parent, Nancy. Blooming bows. New York: Disney Press, 2013.

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Book chapters on the topic "Minnie Mouse"

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Han, Liangxiu, Jano van Hemert, Richard Baldock, and Malcolm Atkinson. "Automating Gene Expression Annotation for Mouse Embryo." In Advanced Data Mining and Applications, 469–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03348-3_46.

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Li, Dongguang. "DGL Global Strategies in DNA Microarray Gene Expression Analysis and Data Mining for Human Blood Cancers." In Mouse Models of Human Blood Cancers, 259–81. New York, NY: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-69132-9_11.

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Eppig, Janan T., Cynthia L. Smith, Judith A. Blake, Martin Ringwald, James A. Kadin, Joel E. Richardson, and Carol J. Bult. "Mouse Genome Informatics (MGI): Resources for Mining Mouse Genetic, Genomic, and Biological Data in Support of Primary and Translational Research." In Methods in Molecular Biology, 47–73. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6427-7_3.

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Valdez, Mario Garcia, Juan-J. Merelo, Amaury Hernandez Aguila, and Alejandra Mancilla Soto. "Mining of Keystroke and Mouse Dynamics to Increase the Engagement of Students with Programming Assignments." In Studies in Computational Intelligence, 41–61. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16469-0_3.

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"3. “You’ve Got to Really Be Minnie” Building a Better Mouse, 1928–1933." In The Animated Man, 68–99. University of California Press, 2019. http://dx.doi.org/10.1525/9780520941663-006.

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Yee, David P., and Tim Hunkapiller. "Overview: A System for Tracking and Managing the Results from Sequence Comparison Programs." In Pattern Discovery in Biomolecular Data. Oxford University Press, 1999. http://dx.doi.org/10.1093/oso/9780195119404.003.0017.

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The Human Genome Project was launched in the early 1990s to map, sequence, and study the function of genomes derived from humans and a number of model organisms such as mouse, rat, fruit fly, worm, yeast, and Escherichia coli. This ambitious project was made possible by advances in high-speed DNA sequencing technology (Hunkapiller et al., 1991). To date, the Human Genome Project and other large-scale sequencing projects have been enormously successful. The complete genomes of several microbes (such as Hemophilus influenzae Rd, Mycoplasma genitalium, and Methanococcus jannaschii) have been completely sequenced. The genome of bacteriophage T4 is complete, and the 4.6-megabase sequence of E. coli and the 13-megabase genome of Saccharomyces cerevisiae have just recently also been completed. There are 71 megabases of the nematode Caenorhabditis elegans available. Six megabases of mouse and 60 megabases of human genomic sequence have been finished, which represent 0.2% and 2% of their respective genomes. Finally, more than 1 million expressed sequence tags derived from human and mouse complementary DNA expression libraries are publicly available. These public data, in addition to private and proprietary DNA sequence databases, represent an enormous information-processing challenge and data-mining opportunity. The need for common interfaces and query languages to access heterogeneous sequence databases is well documented, and several good systems are well underway to provide those interfaces (Woodsmall and Benson, 1993; Marr, 1996). Our own work on database and program interoperability in this domain and in computational chemistry (Gushing, 1995) has shown, however, that providing the interface is but the first step toward making these databases fully useful to the researcher. (Here, the term “database” means a collection of data in electronic form, which may not necessarily be physically deposited in a database management system [DBMS]. A scientist’s database could thus be a collection of flat files, where the term “database” means “data stored in a DBMS” is clear from the context.) Deciphering the genomes of sequenced organisms falls into the realm of analysis; there is now plenty of sequence data. The most common form of sequence analysis involves the identification of homologous relationships among similar sequences.
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Morgan, Hugh, Michelle Simon, and Ann-Marie Mallon. "Accessing and Mining Data from Large-Scale Mouse Phenotyping Projects." In International Review of Neurobiology, 47–70. Elsevier, 2012. http://dx.doi.org/10.1016/b978-0-12-398323-7.00003-3.

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Singer, Donald, and W. David Menzie. "Mineral Resources and Society." In Quantitative Mineral Resource Assessments. Oxford University Press, 2010. http://dx.doi.org/10.1093/oso/9780195399592.003.0005.

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Modern society cannot live without electric and electronic products, concrete, glass, fertilizers, ceramics, motor vehicles, airplanes, refrigerators, stoves, and medical equipment, all of which are made with products of mining. In the 1950s and again in the 1970s there was serious concern about whether we would run out of mineral resources. This recurring theme is driven largely by the increasing amounts of mineral material produced from mines and used by society over time. One of the most striking aspects of the increasing quantities of mineral materials produced has been that prices of many minerals have been declining for more than 100 years. Historically, prices of nonfuel mineral materials have declined relative to consumer goods and wages (Barnett and Morse, 1963). The declining prices have had a positive influence on general economies of mineral users by reducing prices of the factors of production of finished goods. Because mineral commodities are the building blocks of so many industries and products, the declining prices reverberate throughout the economy. Declining mineral commodity prices have largely been due to the successes of mining engineers in repeatedly lowering mining and processing costs and of geologists in lowering discovery costs of mineral deposits. Demonstrating the variability of commodity prices, between 2003 and 2008 prices have dramatically increased, and in 2008 they declined again. Understanding how it is possible to have both increasing production and decreasing and more recently increasing and then decreasing prices of minerals is important to assessors and to decision-makers. Decision-makers, whether concerned about regional development, exploration, or land management, are faced with the dilemma of obtaining new information, or allowing or encouraging others to obtain it, and the possible benefits and costs of development if mineral deposits of value are discovered. The intent in this chapter is to provide decision-makers and assessors a modern perspective on the geologic controls of mineral supply and demand and on the importance to supply of different kinds of mineral deposits and occurrences.
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Cliff, A. D., M. R. Smallman-Raynor, P. Haggett, D. F. Stroup, and S. B. Thacker. "Environmental Changes: Ecological Modifications." In Infectious Diseases: A Geographical Analysis. Oxford University Press, 2009. http://dx.doi.org/10.1093/oso/9780199244737.003.0017.

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Diseases originate, spread, and persist or wither, within a specific environmental context. For the entire time during which humans have lived on the earth, this environmental context has changed and, viewed from the beginning of a new millennium, all the available evidence suggests that the environment is set to change further and faster than at any other time in human history. In this chapter, we explore aspects of the changing environmental terrain in which diseases spread, and how these changes have served to promote the emergence and resurgence of infectious agents. Anthropogenic environmental changes and ecological modifications that promote the emergence and resurgence of infectious diseases are numerous and include deforestation and reforestation, road construction, agricultural development, dam building, irrigation and water control schemes, coastal zone degradation and wetland modification, mining and urbanization, and macro- and micro-climate change and variability (Morse 1995; Patz, Graczyk, et al. 2000; Patz, Daszak, et al. 2004; McMichael 2004). As Patz, Daszak, et al. (2004: 1092) observe, these changes and modifications can, in turn, provoke a ‘cascade effect’ of habitat fragmentation, ecosystem degradation, and biodiversity loss, pollution, poverty, and human migration that serve to amplify the risks of disease emergence and spread. Examples of infectious diseases that are known or suspected to be especially prone to the effects of environmental and land use change are given in Table 7.1. Of the many environmental and land use changes that can facilitate the processes of infectious disease emergence and resurgence, we have selected the five interlinked factors in Figure 7.1 for study here. We illustrate each factor with special reference to one or more examples drawn from the sample diseases and regions listed in Table 7.2. Our examples include: agricultural development and Argentine haemorrhagic fever in South America (Section 7.2); water control schemes and Rift Valley fever in Africa and the eastern Mediterranean (Section 7.3); deforestation and Nipah viral disease in the western Pacific (Section 7.4.1); reforestation and Lyme disease in North America (Section 7.4.2); climate variability and hantavirus pulmonary syndrome in North America (Section 7.5); and natural disasters and disease in North America and South-East Asia (Section 7.6).
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Conference papers on the topic "Minnie Mouse"

1

Yildirim, Eda D., Selc¸uk Gu¨c¸eri, and Wei Sun. "Effect of Oxygen-Radio Frequency Plasma Treatment on Three Dimensional Poly(ε-Caprolactone) Scaffolds." In ASME 2007 International Manufacturing Science and Engineering Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/msec2007-31169.

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In the present study, the effect of oxygen-based plasma treatment on the three dimensional poly (ε-caprolactone) (PCL) was analyzed in terms of surface wettability, surface energy, and surface biocompatibility. The surface treatment was carried out for 1, 3, and 5 minutes durations on three dimensional PCL scaffolds at atmospheric pressure using a radio frequency (RF) plasma treatment system. The solid surface energies of the modified and unmodified PCL scaffolds were calculated by using the Owens-Wendt’s method. To examine the effect of oxygen plasma treatment on cell-scaffold interaction, mouse osteoblast cell line (7F2) was used. Oxygen plasma treatment contributed in decreasing the hydrophobicity of PCL for the 1-min treatment. A change in the surface energy from 39.98 mN/m for untreated to 52.54 mN/m for 1-min treated was observed by the increment in the polar component of surface energy. However, with the extended treatment times (3-min, and 5 min), the hydrophilicity, and the surface energy remained unaffected. The highest mouse osteoblast cells proliferation rate was observed for the 1-minute treated sample.
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Yang, Sen, Qian Sun, Shuiwang Ji, Peter Wonka, Ian Davidson, and Jieping Ye. "Structural Graphical Lasso for Learning Mouse Brain Connectivity." In KDD '15: The 21th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining. New York, NY, USA: ACM, 2015. http://dx.doi.org/10.1145/2783258.2783391.

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Kirsh, Ilan. "Directions and Speeds of Mouse Movements on a Website and Reading Patterns." In WIMS 2020: The 10th International Conference on Web Intelligence, Mining and Semantics. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3405962.3405982.

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John, Suja Rose, and Conrad S. Tucker. "Quantifying the Price and Demand of Subassemblies in the End of Life Strategy of Product Resynthesis." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34757.

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In the United States alone, millions of tons of waste are generated every year, highlighting the urgency for innovative solutions for waste management. Traditional strategies of reducing the amount of End-of-Life (EOL) products include reuse, recycle, remanufacture and disposal. Recently, resynthesis has been proposed in the design community as an alternate approach that aims to combine assemblies/subassemblies of EOL products from multiple domains to create a ‘new’ product, distinct from its parent products. The original work on resynthesis assumes that there is an equal demand for ‘resynthesized products’ based on the available supply of EOL components that the resynthesized products are composed of. Furthermore, the price was assumed to be equal to the price of similar products on the market. However, such an assumption may underestimate or overestimate the value of resynthesized products, which in turn impacts the demand of these products. Recent research has shown that customer reviews express customers’ true opinion and value for specific products or product features. The authors of this paper propose a data mining methodology to quantify the price and demand for resynthesized products by mining user-generated reviews of products publicly available on the internet. A case study involving a resynthesized electronic mouse and white board eraser is presented to demonstrate the feasibility of the proposed methodology.
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Fu, Ziying, Jia Tang, Cun Zhang, Jing Bai, and Qicai Chen. "Neural Inhibition in Forward Masking of the Mouse Inferior Collicular Neurons: In vivo Intracellular Recording." In 2011 First International Workshop on Complexity and Data Mining (IWCDM). IEEE, 2011. http://dx.doi.org/10.1109/iwcdm.2011.47.

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Taneri, Bahar, Alexey Novoradovsky, and Terry Gaasterland. "Identification of Shadow Exons: Mining for Alternative Exons in Human, Mouse and Rat Comparative Databases." In 2009 20th International Workshop on Database and Expert Systems Application. IEEE, 2009. http://dx.doi.org/10.1109/dexa.2009.43.

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Puria, Sunil, Byron Hartman, Jichul Kim, John S. Oghalai, Anthony J. Ricci, M. Charles Liberman, Christopher A. Shera, and Elizabeth S. Olson. "Three-Dimensional Imaging of the Mouse Organ of Corti Cytoarchitecture for Mechanical Modeling." In WHAT FIRE IS IN MINE EARS: PROGRESS IN AUDITORY BIOMECHANICS: Proceedings of the 11th International Mechanics of Hearing Workshop. AIP, 2011. http://dx.doi.org/10.1063/1.3658111.

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Park, HS, S. Park, JS Koo, JH Cho, JM Park, S.-I. Kim, and B.-W. Park. "Abstract P2-05-03: Mouse double minute 2 nuclear expression as a prognostic marker in patients with breast cancer." In Abstracts: Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium‐‐ Dec 4‐8, 2012; San Antonio, TX. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/0008-5472.sabcs12-p2-05-03.

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Ren, Tianying, Wenxuan He, Christopher A. Shera, and Elizabeth S. Olson. "Measurement of Basilar Membrane, Reticular Lamina, and Tectorial Membrane Vibrations in the Intact Mouse Cochlea." In WHAT FIRE IS IN MINE EARS: PROGRESS IN AUDITORY BIOMECHANICS: Proceedings of the 11th International Mechanics of Hearing Workshop. AIP, 2011. http://dx.doi.org/10.1063/1.3658124.

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Hanemann, Clemens O., Sylwia Ammoun, Marei C. Schmid, and Lu Zhou. "Abstract 2609: The role of focal adhesion kinase (FAK), PI3K/AKT and p53/mouse double minute 2 homologue (MDM2) complex in the pathobiology of Merlin-deficient tumors." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2609.

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