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1

Yaghi, Shadi, Joshua Z. Willey, and Pooja Khatri. "Minor ischemic stroke." Neurology: Clinical Practice 6, no. 2 (2016): 157–63. http://dx.doi.org/10.1212/cpj.0000000000000234.

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Sreedharan, S. Erat, J. Vali Sayed, V. P. Vipina, M. Mohan, R. Paul, and P. Sylaja. "Post stroke dysphagia and disability in minor strokes." Journal of the Neurological Sciences 405 (October 2019): 13. http://dx.doi.org/10.1016/j.jns.2019.10.442.

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Kelley, Roger E., and Joseph R. Berger. "TIA and minor stroke." Postgraduate Medicine 91, no. 6 (1992): 197–211. http://dx.doi.org/10.1080/00325481.1992.11701322.

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Hurford, Robert, Linxin Li, Nicola Lovett, Magdalena Kubiak, Wilhelm Kuker, and Peter M. Rothwell. "Prognostic value of “tissue-based” definitions of TIA and minor stroke." Neurology 92, no. 21 (2019): e2455-e2461. http://dx.doi.org/10.1212/wnl.0000000000007531.

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ObjectiveSince use of diffusion-weighted imaging (DWI) positivity in the “tissue-based” definition of stroke in patients with a clinical TIA is supported by the high associated 90-day risk of recurrent stroke, we aimed to determine long-term prognostic significance, stratified by etiologic subtype, and whether the same tissue-based distinction is predictive in minor strokes.MethodsConsecutive eligible patients with TIA or minor stroke (NIH Stroke Scale [NIHSS] ≤3) in the population-based Oxford Vascular Study underwent brain MRI at baseline. Stroke risk on 10-year follow-up was stratified by N
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Rota, Eugenia, Nicola Morelli, Paolo Immovilli, Davide Cerasti, Andrea Zini, and Donata Guidetti. "“Minor” stroke: not a minor, still open question." Journal of Thrombosis and Thrombolysis 49, no. 1 (2019): 132–35. http://dx.doi.org/10.1007/s11239-019-02001-w.

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Kate, M., N. Khan, G. Duba, et al. "B.3 Early motor cortex dysconnectivity and compensatory neuronal reactivity in acute stroke is dependent on the side of stroke." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 52, s1 (2025): S5. https://doi.org/10.1017/cjn.2025.10155.

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Background: We aim to assess the resting state functional connectivity (RSFC) and reactivity with functional near-infrared spectroscopy (fNIRS) in patients with acute stroke compared to age, sex and comorbidity-matched subjects. Methods: Patients with acute anterior circulation stroke syndrome localizing to the right (RH) or left hemisphere (LH) were enrolled. RSFC was assessed using group-level seed-based (Primary Motor cortex,PMC) correlation analysis. Finger-tapping-associated relative oxygen Hemoglobin (ΔHbO) changes were analyzed with generalized linear model regression. Results: 127 part
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Hastrup, Sidsel, Soren P. Johnsen, Martin Jensen, et al. "Specialized Outpatient Clinic vs Stroke Unit for TIA and Minor Stroke." Neurology 96, no. 8 (2021): e1096-e1109. http://dx.doi.org/10.1212/wnl.0000000000011453.

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ObjectiveTo evaluate the effects of an outpatient clinic setup for minor stroke/TIA using subsequent admission of patients at high risk of recurrent stroke.MethodsWe performed a cohort study of all patients with suspected minor stroke/TIA seen in an outpatient clinic at Aarhus University Hospital, Denmark, between September 2013 and August 2014. Patients with stroke were compared to historic (same hospital) and contemporary (another comparable hospital) matched, hospitalized controls on nonprioritized outcomes: length of stay, readmissions, care quality (10 process–performance measures), and m
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Cucchiara, Brett, Donna Kurowski George, Scott E. Kasner, et al. "Disability after minor stroke and TIA." Neurology 93, no. 7 (2019): e708-e716. http://dx.doi.org/10.1212/wnl.0000000000007936.

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ObjectiveTo examine factors associated with disability following TIA and minor stroke, including poststroke complications such as stroke recurrence, major bleeding, and other adverse medical events.MethodsThe SOCRATES trial randomized patients with TIA/minor stroke (NIH Stroke Scale [NIHSS] score ≤5) within 24 hours of onset. We performed a post hoc analysis of factors associated with disability (modified Rankin Scale [mRS] score >1). TIA and minor stroke were analyzed separately. Patients with premorbid mRS >0 were excluded.ResultsAt 90 days, 687/3,663 (19%) patients with stroke were di
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Fischer, Urs, Adrian Baumgartner, Marcel Arnold, et al. "What Is a Minor Stroke?" Stroke 41, no. 4 (2010): 661–66. http://dx.doi.org/10.1161/strokeaha.109.572883.

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Rukovets, Olga. "For Your Patients-Minor Stroke." Neurology Today 18, no. 16 (2018): 30–31. http://dx.doi.org/10.1097/01.nt.0000544632.31150.7b.

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Yoo, Joonsang, Sung-Il Sohn, Jinkwon Kim, et al. "Delayed Intravenous Thrombolysis in Patients with Minor Stroke." Cerebrovascular Diseases 46, no. 1-2 (2018): 52–58. http://dx.doi.org/10.1159/000492123.

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Background: The actions and responses of the hospital personnel during acute stroke care in the emergency department (ED) may differ according to the severity of a patient’s stroke symptoms. We investigated whether the time from arrival at ED to various care steps differed between patients with minor and non-minor stroke who were treated with intravenous tissue plasminogen activator (IV tPA). Methods: We included consecutive patients who received IV tPA during a 1.5 year-period in 5 hospitals. Minor stroke was defined as a National Institutes of Health Stroke Scale (NIHSS) score < 5. We com
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Kim, Dae-Hyun. "Intravenous Thrombolysis and Endovascular Thrombectomy in Acute Ischemic Stroke with Minor Symptom." Journal of the Korean Neurological Association 39, no. 1 (2021): 10–18. http://dx.doi.org/10.17340/jkna.2021.1.2.

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More than 50% of all patients with ischemic stroke initially present with mild symptoms. Despite the mild clinical presentation, a high percentage of these patients develop stroke progression with consequent disability, recurrent stroke, or death at follow-up. Intravenous thrombolysis with recombinant tissue plasminogen activator within 4.5 hours has been proven to be an effective treatment for acute ischemic stroke, but the risk-benefit ratio of this therapeutic approach remains still unclear in patients with mild stroke. Many patients with mild stroke are frequently excluded from thrombolysi
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Zhu, Bihong, Yuesong Pan, Jing Jing, et al. "Neutrophil counts, neutrophil ratio, and new stroke in minor ischemic stroke or TIA." Neurology 90, no. 21 (2018): e1870-e1878. http://dx.doi.org/10.1212/wnl.0000000000005554.

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ObjectiveEvidence about whether neutrophil counts or neutrophil ratio is associated with new stroke is scant. The aim of this study is to assess the association of neutrophil counts or neutrophil ratio with a new stroke in patients with minor stroke or TIA.MethodsWe derived data from the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events trial. Patients with a minor stroke or TIA were categorized into 4 groups according to the quartile of neutrophil counts or neutrophil ratio. The primary outcome was a new stroke (ischemic or hemorrhagic), and secondary outcomes i
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Burvill, P. W., G. A. Johnson, K. D. Jamrozik, C. S. Anderson, E. G. Stewart-Wynne, and T. M. H. Chakera. "Prevalence of Depression After Stroke: The Perth Community Stroke Study." British Journal of Psychiatry 166, no. 3 (1995): 320–27. http://dx.doi.org/10.1192/bjp.166.3.320.

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BackgroundThe Perth Community Stroke Study (PCSS) was a population-based study of the incidence, cause, and outcome of acute stroke.MethodSubjects from the study were assessed initially, by examination and interview, and at four- and 12-month follow-ups to determine differences in prevalence of depression between the sexes and between patients with first-ever and recurrent strokes.ResultsThe prevalence of depressive illness four months after stroke in 294 patients from the PCSS was 23% (18–28%), 15% (11–19%) major depression and 8% (5–11 %) minor depression. There were no significant differenc
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Manchala, Shashidhar, Vinod Kumar Mehta, and Sitaram Barath. "A study of short term and long term risk of ischemic stroke and other vascular events following early treatment of tia and minor stroke in a tertiary centre in North India." IP Indian Journal of Neurosciences 7, no. 2 (2021): 138–43. http://dx.doi.org/10.18231/j.ijn.2021.023.

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Transient ischemic attack and minor ischemic stroke are associated with early recurrence and deterioration respectively. There is a high risk of stroke after TIA ranging between 10-20% in the ensuing 90 days in the various studies. There are various clinical and imaging factors which predict the early risk of stroke after a TIA. To evaluate the short term and long term risk of ischemic stroke following early treatment of TIA and minor stroke. TIA is defined as sudden focal neurologic deficit of presumed vascular origin lasting less than 24 hours. Minor ischemic stroke is defined as National in
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McHutchison, Caroline A., Vera Cvoro, Stephen Makin, Francesca M. Chappell, Kirsten Shuler, and Joanna M. Wardlaw. "Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke." Journal of Neurology, Neurosurgery & Psychiatry 90, no. 4 (2018): 436–43. http://dx.doi.org/10.1136/jnnp-2018-319134.

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ObjectiveMany studies examining stroke outcomes focus on more severe strokes or have short follow-up periods, so the long-term outcomes post-minor ischaemic stroke are unclear.MethodsWe recruited participants from inpatient and outpatient services with a lacunar or minor cortical ischaemic stroke (National Institutes of Health Stroke Scale score <8) and assessed current and premorbid cognitive functioning (Addenbrooke’s Cognitive Examination–Revised (ACE-R), National Adult Reading Test (NART)), physical functioning (Timed Get Up and Go (TUG), 9-Hole Peg Test (9HPT)), dependency (modified Ra
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Pan, Yuesong, Jing Jing, Weiqi Chen, et al. "Risks and benefits of clopidogrel–aspirin in minor stroke or TIA." Neurology 88, no. 20 (2017): 1906–11. http://dx.doi.org/10.1212/wnl.0000000000003941.

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Objective:To investigate the short-term time course risks and benefits of clopidogrel with aspirin in minor ischemic stroke or TIA.Methods:Data were derived from the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial. The primary outcome was a new ischemic stroke. Safety outcomes included any bleeding and moderate to severe bleeding. Time course analyses were performed for the outcomes of both stroke and bleeding.Results:A total of 145 (71.1%), 13 (6.4%), and 12 (5.9%) of 204 new ischemic strokes in the clopidogrel–aspirin group vs 223 (75.6%), 19 (
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Basu, Elora, Setareh Salehi Omran, Hooman Kamel, and Neal S. Parikh. "Sex differences in the risk of recurrent ischemic stroke after ischemic stroke and transient ischemic attack." European Stroke Journal 6, no. 4 (2021): 367–73. http://dx.doi.org/10.1177/23969873211058568.

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Background Sex differences in stroke outcomes have been noted, but whether this extends to stroke recurrence is unclear. We examined sex differences in recurrent stroke using data from the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) trial. Patients and methods We assessed the risk of recurrent stroke in women compared to men using data from the POINT trial. Adults >18 years old were randomized within 12 hours of onset of minor ischemic stroke or transient ischemic attack (TIA), and followed for up to 90 days for ischemic stroke, our primary outcome. We used Cox
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Kontou, Eirini, Marion Walker, Shirley Thomas, et al. "Optimising Psychoeducation for Transient Ischaemic Attack and Minor Stroke Management (OPTIMISM): Protocol for a feasibility randomised controlled trial." AMRC Open Research 2 (June 29, 2020): 24. http://dx.doi.org/10.12688/amrcopenres.12911.1.

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Background: A transient ischaemic attack (TIA) and minor stroke are medical emergencies and often a warning sign of future strokes if remain untreated. Few studies have investigated the long-term psychosocial effects of TIA and minor stroke. Secondary prevention and medical management are often the primary focus with limited access offered for further psychosocial support. Psychoeducational interventions can provide education and advice to people with physical health conditions and, with suitable tailoring, could be appropriate for people after TIA and minor stroke. This study aims to develop
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Cashion, Catelyn, Yash Gawarikar, and Ronak Patel. "081 Description of a stroke unit mimic admissions." Journal of Neurology, Neurosurgery & Psychiatry 89, no. 6 (2018): A33.1—A33. http://dx.doi.org/10.1136/jnnp-2018-anzan.80.

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IntroductionThere is evidence to support both clinically and economically that stroke units improve stroke outcomes, but this is offset by high stroke mimics rates, which account for up to quarter of stroke unit admissions. There is no Australian data looking at stroke mimic rates and the time of day when they are admitted.MethodsWe conducted a retrospective cross-sectional study at Calvary Public Hospital, Bruce from May 2014 to May 2017 looking at stroke unit admission rates and mimic types. We collected data on the times of stroke unit admission, business hours Monday to Friday 0800–1630 ho
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Li, Jiejie, Yuesong Pan, Mengxing Wang, et al. "Predictive Role of hsCRP in Recurrent Stroke Differed According to Severity of Cerebrovascular Disease: Analysis from a Prospective Cohort Study." Journal of Clinical Medicine 12, no. 4 (2023): 1676. http://dx.doi.org/10.3390/jcm12041676.

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Elevated levels of high-sensitivity C-reactive protein (hsCRP) were associated with an increased risk of recurrent stroke. However, it is still unknown whether the predictive value of hsCRP differed according to the severity of cerebrovascular disease. We used the cohort of the prospective multicenter cohort study of the Third China National Stroke Registry (CNSR-III), in which 10,765 consecutive patients with acute ischemic stroke or transient ischemic attack (TIA) had hsCRP levels measured. Patients were classified into minor stroke, or TIA, and non-minor stroke. The primary outcome was a ne
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Millichap, J. Gordon. "Minor Athletic Trauma and Ischemic Stroke." Pediatric Neurology Briefs 24, no. 4 (2010): 31. http://dx.doi.org/10.15844/pedneurbriefs-24-4-10.

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Crespi, Vittorio, Massimiliano Braga, Sandro Beretta, Antonio Carolei, Angelo Bignamini, and Simona Sacco. "A practical definition of minor stroke." Neurological Sciences 34, no. 7 (2012): 1083–86. http://dx.doi.org/10.1007/s10072-012-1205-8.

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Finch, Emma, Michele Foster, Jennifer Fleming, et al. "Exploring changing needs following minor stroke." Health & Social Care in the Community 28, no. 2 (2019): 347–56. http://dx.doi.org/10.1111/hsc.12866.

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Deplanque, Dominique, Michèle Bastide, and Régis Bordet. "Transient Ischemic Attack and Minor Stroke." Stroke 49, no. 2 (2018): 277–78. http://dx.doi.org/10.1161/strokeaha.117.020013.

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Kasinathan, Ananthanarayanan, Ravikumar Senthilkumaran, Anandhi Chandramohan, Vinoth Saravanan, and P. Soundararajan. "Infantile stroke: consider minor head trauma." Child's Nervous System 34, no. 11 (2018): 2141–42. http://dx.doi.org/10.1007/s00381-018-3945-0.

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Catedra Carame, Carlos, Laura Amaya Pascasio, Andres Garcia Pastor, et al. "Minor stroke can cause major disability: Identification of poor prognosis factors in patients with minor stroke." Journal of the Neurological Sciences 429 (October 2021): 119647. http://dx.doi.org/10.1016/j.jns.2021.119647.

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Nguyen, Dung Tien, Ton Duy Mai, Phuong Viet Dao, et al. "Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study." PLOS ONE 19, no. 5 (2024): e0302822. http://dx.doi.org/10.1371/journal.pone.0302822.

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Early neurological deterioration (END) is progressive neurological deterioration with an increase in NIHSS score of 2 points or more in the first 72 hours from the onset of acute ischemic stroke. END increases the risk of poor clinical outcomes at day 90 of ischemic stroke. We will study the frequency, predictors, and outcomes of patients with END in a case-control study at a comprehensive stroke centre in Vietnam. of the design is a descriptive observational study, longitudinal follow-up of patients with minor stroke hospitalized at the Stroke Center of Bach Mai Hospital from December 1, 2023
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Strambo, Davide, Alberto A. Zambon, Luisa Roveri, et al. "Defining Minor Symptoms in Acute Ischemic Stroke." Cerebrovascular Diseases 39, no. 3-4 (2015): 209–15. http://dx.doi.org/10.1159/000375151.

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Background: Thrombolysis is often withheld from acute ischemic stroke patients presenting with mild symptoms; however, up to 40% of these patients end up with a poor outcome when left untreated. Since there is lack of consensus on the definition of minor symptoms, we aimed at addressing this issue by looking for features that would better predict functional outcomes at 3 months. Methods: Among all acute ischemic stroke patients admitted to our Stroke Unit (n = 1,229), we selected a cohort of patients who arrived within 24 hours from symptoms onset, with baseline NIHSS ≤6, not treated with thro
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Leong, Michelle, Jillian M. Stang, Natasha McGuire, Eddy Lang, Shelagh B. Coutts, and Catherine Patocka. "Regional Variation in Transient Ischemic Attack and Minor Stroke in Alberta Emergency Departments." Stroke 51, no. 6 (2020): 1820–24. http://dx.doi.org/10.1161/strokeaha.119.027960.

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Background and Purpose— Multiple studies have shown the 90-day risk of stroke following an emergency department (ED) diagnosis of transient ischemic attack (TIA) or minor stroke is significant, with the greatest risk of recurrence being within the first 24 to 48 hours following initial symptom onset. This study explored regional differences in ED disposition, neuroimaging, and subsequent 90-day stroke risk of patients diagnosed with TIA or minor stroke in Alberta. Methods— We used administrative databases to identify ED visits, neuroimaging, and 90-day return visits for TIA or minor stroke in
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Couillard, Philippe, Alexandre Y. Poppe, and Shelagh B. Coutts. "Predicting recurrent stroke after minor stroke and transient ischemic attack." Expert Review of Cardiovascular Therapy 7, no. 10 (2009): 1273–81. http://dx.doi.org/10.1586/erc.09.105.

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Frank, Robert A., Santanu Chakraborty, Trevor McGrath, et al. "Diagnostic accuracy of whole-brain computed tomography perfusion for detection of ischemic stroke in patients with mild neurological symptoms." Neuroradiology Journal 31, no. 5 (2018): 464–72. http://dx.doi.org/10.1177/1971400918770898.

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Mild and minor acute neurological symptoms may lead to diagnostic uncertainty, resulting in a heterogeneous group of patients with true ischemic events and stroke mimics with a potential for poor outcomes. More than half of ischemic stroke patients present as minor strokes (National Institutes of Health Stroke Scale score <6). Whole-brain computed tomography perfusion can be used as a diagnostic test for minor stroke, offering a potential method of reducing diagnostic uncertainty in these patients. We hypothesize that whole-brain computed tomography perfusion imaging features could accurate
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Camden, Marie-Christine, Michael D. Hill, Andrew M. Demchuk, et al. "Historic Stroke Motor Severity Score Predicts Progression in TIA/Minor Stroke." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 41, no. 1 (2014): 19–23. http://dx.doi.org/10.1017/s0317167100016206.

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Background:transient ischemic attack (tIA) and minor stroke have a high risk of early neurological deterioration, and patients who experience early improvement are at risk of deterioration. We generated a score for quantifying the worst reported motor and speech deficits and assessed whether this predicted outcome.Methods:510 tIA or minor stroke (NIHSS>4) patients were included. the Historical Stroke Severity Score (HSSS) prospectively quantified the patient's description of the worst motor or speech deficits. the HSSS was rated at the time of first assessment with more severe deficits scor
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Seadon, Scott, and Eddy Lang. "Clopidogrel with aspirin versus aspirin alone in prevention of stroke following transient ischemic attack or acute minor stroke." CJEM 17, no. 3 (2015): 315–17. http://dx.doi.org/10.2310/8000.2014.141510.

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Clinical questionFollowing transient ischemic attack or acute minor stroke, does the combination of clopidogrel and aspirin reduce the risk of stroke greater than aspirin alone?Article chosenWang Y, Wang Y, Zhao X, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med 2013;369:11-9.ObjectiveThe primary outcome measured in this study was ischemic or hemorrhagic stroke at 90 days of follow-up in groups assigned to treatment with a combination of aspirin and clopidogrel or aspirin alone following transient ischemic attack or acute minor stroke. The secon
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Luengo-Fernandez, Ramon, Linxin Li, Louise Silver, Sergei Gutnikov, Nicola C. Beddows, and Peter M. Rothwell. "Long-Term Impact of Urgent Secondary Prevention After Transient Ischemic Attack and Minor Stroke: Ten-Year Follow-Up of the EXPRESS Study." Stroke 53, no. 2 (2022): 488–96. http://dx.doi.org/10.1161/strokeaha.121.034279.

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Background and Purpose: Urgent assessment aimed at reducing stroke risk after transient ischemic attack or minor stroke is cost-effective over the short-term. However, it is unclear if the short-term impact is lost on long-term follow-up, with recurrent events being delayed rather than prevented. By 10-year follow-up of the EXPRESS study (Early Use of Existing Preventive Strategies for Stroke), previously showing urgent assessment reduced 90-day stroke risk by 80%, we determined whether that early benefit was still evident long-term for stroke risk, disability, and costs. Methods: EXPRESS was
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Kapral, Moira K., Ruth Hall, Jiming Fang, et al. "Predictors of Hospitalization in Patients With Transient Ischemic Attack or Minor Ischemic Stroke." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 43, no. 4 (2016): 523–28. http://dx.doi.org/10.1017/cjn.2016.12.

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AbstractBackground: Transient ischemic attack (TIA) and minor stroke are associated with a substantial risk of subsequent stroke; however, there is uncertainty about whether such patients require admission to hospital for their initial management. We used data from a clinical stroke registry to determine the frequency and predictors of hospitalization for TIA or minor stroke across the province of Ontario, Canada. Methods: The Ontario Stroke Registry collects information on a population-based sample of all patients seen in the emergency department with acute stroke or TIA in Ontario. We identi
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Lim, Andy, Henry Ma, John Ly, et al. "Comparison of Dual Antiplatelet Therapies for Minor, Nondisabling, Acute Ischemic Stroke: A Bayesian Network Meta-Analysis." JAMA Network Open 7, no. 5 (2024): e2411735. http://dx.doi.org/10.1001/jamanetworkopen.2024.11735.

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ImportanceDual antiplatelet therapy (DAPT) appears to be an effective treatment option for minor (nondisabling) acute ischemic stroke. This conclusion is based on trials that include both transient ischemic attack (TIA) and minor stroke; however, these 2 conditions may differ.ObjectiveTo compare DAPT regimens specifically for minor stroke.Data SourcesPubMed was searched for randomized clinical trials published up to November 4, 2023. Search terms strategy included TIA, transient ischemic attack, minor stroke, or moderate stroke, with the filter randomized controlled trial. Unpublished data on
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Macêdo, Isabella Sales de, Rafaela Almeida Alquéres, Lorena Souza Viana Schneider, Paulo Puglia Júnior, and Adriana Bastos Conforto. "Rate of complications due to carotid angioplasty in a tertiary university hospital." Revista de Medicina 97, Suppl.1 (2018): 28. http://dx.doi.org/10.11606/issn.1679-9836.v97isuppl.1p28-28.

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Introduction: Stenoses greater than 50% in the cervical internal carotid artery cause up to 8% of all ischemic strokes. Carotid artery stenting (CAS) is an effective alternative to prevent cerebrovascular events to occur. According to recommendations from the American Heart Association/American Stroke Association, CAS is indicated for symptomatic patients with internal carotid stenosis greater than 70% (measured by non-invasive methods), as long as the risk for periprocedural stroke or death is less than 6%. There is few information about complication rates of CAS in developing countries. Obje
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Wiśniewski, Adam, Joanna Sikora, Aleksandra Karczmarska-Wódzka, and Przemysław Sobczak. "A Combination of Aspirin and Clopidogrel Predict More Favorable Dynamics of Platelet Reactivity versus Clopidogrel Alone in the Acute Phase of Minor Stroke." Healthcare 9, no. 6 (2021): 628. http://dx.doi.org/10.3390/healthcare9060628.

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Background: The combined use of clopidogrel and aspirin is recommended for the short-term (21 days) therapy of minor stroke or transient ischemic attack. Previous studies have demonstrated its efficacy and superiority over treatment with a single antiplatelet agent. However, there is insufficient support for the advantages of such therapy based on platelet function testing. We aimed to compare the effect of the concomitant use of clopidogrel and aspirin versus clopidogrel alone on the dynamics of platelet reactivity over time to determine the appropriate antiplatelet treatment strategy for min
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Béjot, Yannick, Ziyah Mehta, Maurice Giroud, and Peter M. Rothwell. "Impact of Completeness of Ascertainment of Minor Stroke on Stroke Incidence." Stroke 44, no. 7 (2013): 1796–802. http://dx.doi.org/10.1161/strokeaha.113.000949.

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Amarenco, Pierre, Philippa C. Lavallée, Linsay Monteiro Tavares, et al. "Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke." New England Journal of Medicine 378, no. 23 (2018): 2182–90. http://dx.doi.org/10.1056/nejmoa1802712.

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Millichap, J. Gordon. "Minor Head Injury as Cause of Stroke." Pediatric Neurology Briefs 16, no. 7 (2002): 50. http://dx.doi.org/10.15844/pedneurbriefs-16-7-2.

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Altieri, M., I. Maestrini, A. Mercurio, et al. "Depression after minor stroke: prevalence and predictors." European Journal of Neurology 19, no. 3 (2011): 517–21. http://dx.doi.org/10.1111/j.1468-1331.2011.03583.x.

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Škorňa, Miroslav, Jiří Neumann, Stanislav Peška, and Robert Mikulík. "Transient Ischemic Attack and Minor Stroke Management." Česká a slovenská neurologie a neurochirurgie 79/112, no. 2 (2016): 178–87. http://dx.doi.org/10.14735/amcsnn2016178.

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45

&NA;. "Ticlopidine better than aspirin for minor stroke." Inpharma Weekly &NA;, no. 869 (1993): 15. http://dx.doi.org/10.2165/00128413-199308690-00024.

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46

Prencipe, Massimiliano, Franco Culasso, Maurizia Rasura, et al. "Long-term Prognosis After a Minor Stroke." Stroke 29, no. 1 (1998): 126–32. http://dx.doi.org/10.1161/01.str.29.1.126.

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47

Shi, YuZhi, YuTao Xiang, Yang Yang, et al. "Depression after minor stroke: Prevalence and predictors." Journal of Psychosomatic Research 79, no. 2 (2015): 143–47. http://dx.doi.org/10.1016/j.jpsychores.2015.03.012.

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48

Bhatt, Archit, Alexandra Lesko, Amit Kansara, and Elizabeth Baraban. "Abstract T P328: Patients with Low NIHSS Stroke Scales Have Longer Door to Needle Times: An Analysis of a Telestroke Network." Stroke 46, suppl_1 (2015). http://dx.doi.org/10.1161/str.46.suppl_1.tp328.

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Background: The benefits of intravenous tissue-type plasminogen activator (IV tPA) in acute ischemic stroke are time dependent. We hypothesized that patients with lower stroke scales would have longer door to needle times (DNT), in addition to other time dependent measures, compared to patients with higher stroke scales because emergency rooms more readily start a stroke alert with more severe symptoms. Methods: Data obtained from the 17-partner hospital Providence stroke registry was used to identify AIS (Acute Ischemic Stroke) patients who received IV tPA within 4.5 hours of symptom onset. N
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Ferrari, Julia, Audrey Reynolds, Michael Knoflach, and Marek Sykora. "Acute Ischemic Stroke With Mild Symptoms–To Thrombolyse or Not to Thrombolyse?" Frontiers in Neurology 12 (November 18, 2021). http://dx.doi.org/10.3389/fneur.2021.760813.

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Management of stroke with minor symptoms may represent a therapeutical dilemma as the hemorrhage risk of acute thrombolytic therapy may eventually outweigh the stroke severity. However, around 30% of patients presenting with minor stroke symptoms are ultimately left with disability. The objective of this review is to evaluate the current literature and evidence regarding the management of minor stroke, with a particular emphasis on the role of IV thrombolysis. Definition of minor stroke, pre-hospital recognition of minor stroke and stroke of unknown onset are discussed together with neuroimagi
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Wang, Xun, Yi Dong, Qiang Dong, and David Wang. "Should patients with minor strokes be given thrombolytics?" Stroke and Vascular Neurology, August 3, 2024, svn—2024–003451. http://dx.doi.org/10.1136/svn-2024-003451.

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Mild stroke symptoms are cited as the reason for not using tissue-type plasminogen activator in 29–43% of time-eligible patients. Previous studies suggested that not all of these patients had a good recovery or even survival to hospital discharge. Since then, stroke guidelines worldwide recommended thrombolysis in minor but disabling strokes.Dual antiplatelet treatment with aspirin and clopidogrel was more effective than aspirin alone for reducing subsequent events in patients with minor stroke if started within 24 hours of onset in both CHANCE (Clopidogrel in High-Risk Patients with Acute Non
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