Relevant bibliographies by topics / Mitosom

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Mitosom'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Mitosom"

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Santos, Herbert J., Yuki Hanadate, Kenichiro Imai, and Tomoyoshi Nozaki. "An Entamoeba-Specific Mitosomal Membrane Protein with Potential Association to the Golgi Apparatus." Genes 10, no. 5 (2019): 367. http://dx.doi.org/10.3390/genes10050367.

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The aerobic mitochondrion had undergone evolutionary diversification, most notable among lineages of anaerobic protists. Entamoeba is one of the genera of parasitic protozoans that lack canonical mitochondria, and instead possess mitochondrion-related organelles (MROs), specifically mitosomes. Entamoeba mitosomes exhibit functional reduction and divergence, most exemplified by the organelle’s inability to produce ATP and synthesize iron-sulfur cluster. Instead, this organelle is capable of sulfate activation, which has been linked to amoebic stage conversion. In order to understand other uniqu
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Martincová, Eva, Luboš Voleman, Jan Pyrih, et al. "Probing the Biology of Giardia intestinalis Mitosomes UsingIn VivoEnzymatic Tagging." Molecular and Cellular Biology 35, no. 16 (2015): 2864–74. http://dx.doi.org/10.1128/mcb.00448-15.

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Giardia intestinalisparasites contain mitosomes, one of the simplest mitochondrion-related organelles. Strategies to identify the functions of mitosomes have been limited mainly to homology detection, which is not suitable for identifying species-specific proteins and their functions. Anin vivoenzymatic tagging technique based on theEscherichia colibiotin ligase (BirA) has been introduced toG. intestinalis; this method allows for the compartment-specific biotinylation of a protein of interest. Known proteins involved in the mitosomal protein import werein vivotagged, cross-linked, and used to
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Rada, Petr, Ondřej Šmíd, Robert Sutak, et al. "The Monothiol Single-Domain Glutaredoxin Is Conserved in the Highly Reduced Mitochondria of Giardia intestinalis." Eukaryotic Cell 8, no. 10 (2009): 1584–91. http://dx.doi.org/10.1128/ec.00181-09.

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ABSTRACT The highly reduced mitochondria (mitosomes) of Giardia intestinalis are recently discovered organelles for which, it was suggested, iron-sulfur cluster assembly was their only conserved function. However, only an incomplete set of the components required for FeS cluster biogenesis was localized to the mitosomes. Via proteomic analysis of a mitosome-rich cellular fraction together with immunofluorescence microscopy, we identified a novel mitosomal protein homologous to monothiol glutaredoxins containing a CGFS motif at the active site. Sequence analysis revealed the presence of long no
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Santos, Herbert J., Yoko Chiba, Takashi Makiuchi, et al. "Import of Entamoeba histolytica Mitosomal ATP Sulfurylase Relies on Internal Targeting Sequences." Microorganisms 8, no. 8 (2020): 1229. http://dx.doi.org/10.3390/microorganisms8081229.

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Mitochondrial matrix proteins synthesized in the cytosol often contain amino (N)-terminal targeting sequences (NTSs), or alternately internal targeting sequences (ITSs), which enable them to be properly translocated to the organelle. Such sequences are also required for proteins targeted to mitochondrion-related organelles (MROs) that are present in a few species of anaerobic eukaryotes. Similar to other MROs, the mitosomes of the human intestinal parasite Entamoeba histolytica are highly degenerate, because a majority of the components involved in various processes occurring in the canonical
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Emelyanov, Victor V., and Alina V. Goldberg. "Fermentation enzymes of Giardia intestinalis, pyruvate:ferredoxin oxidoreductase and hydrogenase, do not localize to its mitosomes." Microbiology 157, no. 6 (2011): 1602–11. http://dx.doi.org/10.1099/mic.0.044784-0.

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It is becoming increasingly clear that the so-called remnant organelles of microaerophilic unicellular eukaryotes, hydrogenosomes and mitosomes, are significantly reduced versions of mitochondria. They normally lack most of the classic mitochondrial attributes, such as an electron transport chain and a genome. While hydrogenosomes generate energy by substrate-level phosphorylation along a hydrogen-producing fermentation pathway, involving iron–sulfur-cluster-containing enzymes pyruvate : ferredoxin oxidoreductase (PFO) and hydrogenase, whether mitosomes participate in ATP synthesis is currentl
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Steinbeck, RG. "Pathologic mitoses and pathology of mitosis in tumorigenesis." European Journal of Histochemistry 45, no. 4 (2009): 311. http://dx.doi.org/10.4081/1640.

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Mi-ichi, Fumika, Akira Nozawa, Hiroki Yoshida, Yuzuru Tozawa, and Tomoyoshi Nozaki. "Evidence that the Entamoeba histolytica Mitochondrial Carrier Family Links Mitosomal and Cytosolic Pathways through Exchange of 3′-Phosphoadenosine 5′-Phosphosulfate and ATP." Eukaryotic Cell 14, no. 11 (2015): 1144–50. http://dx.doi.org/10.1128/ec.00130-15.

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ABSTRACT Entamoeba histolytica , a microaerophilic protozoan parasite, possesses mitosomes. Mitosomes are mitochondrion-related organelles that have largely lost typical mitochondrial functions, such as those involved in the tricarboxylic acid cycle and oxidative phosphorylation. The biological roles of Entamoeba mitosomes have been a long-standing enigma. We previously demonstrated that sulfate activation, which is not generally compartmentalized to mitochondria, is a major function of E. histolytica mitosomes. Sulfate activation cooperates with cytosolic enzymes, i.e., sulfotransferases (SUL
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Kantsavaya, I., and O. Alekseenko. "Effect of Beta-lactam Antibiotics on Microscopic Parameters in the Allium-test." Bulletin of Science and Practice 5, no. 10 (2019): 25–31. http://dx.doi.org/10.33619/2414-2948/47/03.

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The work examines the effect of beta-lactam antibiotics (cefotaxime, ampicillin, augmentin) on the pathology of mitosis in the Allium–test. Research methods: Allium–test, cytogenetic analysis, statistical analysis. It was established that the use of individual tested beta-lactam antibiotics increases the percentage of pathological mitoses in the cell by 1.8–3.3 times compared with the value in the control. With the combined use of cefotaxime and Augmentin, synergism appeared, as a result, the value of mitosis pathology turned out to be at the level of the number in the control; minimally repre
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Ma, Li, Xiangshan Zhao, and Xueliang Zhu. "Mitosin/CENP-F in mitosis, transcriptional control, and differentiation." Journal of Biomedical Science 13, no. 2 (2006): 205–13. http://dx.doi.org/10.1007/s11373-005-9057-3.

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Helfer, Hanspeter, and Amy S. Gladfelter. "AgSwe1p Regulates Mitosis in Response to Morphogenesis and Nutrients in Multinucleated Ashbya gossypii Cells." Molecular Biology of the Cell 17, no. 10 (2006): 4494–512. http://dx.doi.org/10.1091/mbc.e06-03-0215.

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Nuclei in the filamentous, multinucleated fungus Ashbya gossypii divide asynchronously. We have investigated what internal and external signals spatially direct mitosis within these hyphal cells. Mitoses are most common near cortical septin rings found at growing tips and branchpoints. In septin mutants, mitoses are no longer concentrated at branchpoints, suggesting that the septin rings function to locally promote mitosis near new branches. Similarly, cells lacking AgSwe1p kinase (a Wee1 homologue), AgHsl1p (a Nim1-related kinase), and AgMih1p phosphatase (the Cdc25 homologue that likely coun
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Dissertations / Theses on the topic "Mitosom"

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Cortez, Beatriz de Araujo. "Interação da crisotila com células de carcinoma de pulmão humano em cultura: interferência com a mitose utilizando genes repórteres e microscopia em tempo real e estudo do potencial genotóxico." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-05042010-134617/.

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Asbesto é um nome geral dado a seis tipos de fibras minerais encontradas naturalmente na crosta terrestre. Estas fibras vêm sendo exploradas industrialmente desde 1970, porém diversos trabalhadores expostos às fibras apresentaram patologias no trato respiratório, como fibroses e carcinomas. Alguns tipos de fibra foram banidos do mercado, porém o tipo de asbesto crisotila ainda pode ser comercializado na maioria dos países. Estudos in vivo e in vitro tentam elucidar as alterações causadas pela exposição à asbesto nos tecidos e nas células que possam estar relacionadas ao aparecimento de doenças
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Cannet, Aude. "Rôle du Rho-GEF Trio dans la division cellulaire." Thesis, Montpellier 2, 2014. http://www.theses.fr/2014MON20124.

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Durant la division cellulaire, la cellule subit des changements importants dans sa forme et son adhésion qui dépendent de l'efficacité du remodelage du cytosquelette d'actine. Ce processus est localement et temporellement régulé pour assurer le bon déroulement de la cytokinèse, l'étape finale de la division cellulaire. Il est contrôlé par les GTPases de la famille Rho via le remodelage du cytosquelette d'actine. Les Rho-GTPases fonctionnent comme des interrupteurs moléculaires, passant d'une forme au repos (liée au GDP) à une forme active (liée au GTP). La forme au repos interagit avec des fac
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Ma, Sheng. "Caractérisation du rôle des protéines phosphatases impliquées dans la déphosphorylation de la protéine kinase Greatwall lors de la sortie de mitose." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS007/document.

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Chez la drolosophile, des mutants de Greatwall présentent des défauts de condensation des chromosomes lors de la mitose. Plus tard, la même équipe a montré que chez le Xénope, Greatwall est nécessaire pour entrer en mitose. L'idée consistant à penser que puisque Greatwall ne permet plus l'entrée en mitose, il joue un rôle dans la boucle qui conduit à l'auto-amplification de MPF. En 2009, notre équipe a montré que Greatwall est réellement impliquée dans l'entrée en mitose, mais de façon indirecte par rapport à la boucle d'amplification de MPF, et cela en contrôlant l'activité de la phosphatase
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Bouguenina, Mohammed El Habib. "La protéine SMYLE (Short MYomegalin Like EB1 binding protein) dans l'organisation d'un complexe centrosomal, la régulation de la nucléation et la stabilisation des microtubules : conséquences sur la migration et la division des cellules cancéreuses." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5060.

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Les microtubules (MT) sont des polymères dynamiques ancrés par leurs extrémités moins aux centres de nucléation alors que leurs extrémités plus, explorent le cytoplasme, jusqu’à être stabilisées. Cette capture des extrémités permet l’organisation du réseau des MT. Les +TIP sont un groupe de protéines qui s’associent aux bouts plus des MT. EB1 est une protéine centrale dans le réseau des +TIP qui régule la dynamique des MT et leur interaction avec les structures d’ancrage des extrémités plus. Par protéomique ciblée, nous avons caractérisé l’interactome d’EB1, et mis en évidence un groupe de pro
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Feizbakhsh, Omid. "La protéine Kinase Haspine comme nouvelle cible thérapeutique : analyse de ses fonctions et caractérisation d'inhibiteurs spécifiques." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1B053.

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Depuis sa découverte en 1994, la protéine kinase Haspine fait l’objet d’un intérêt scientifique croissant en raison de son rôle clé dans la mitose. Elle est impliquée dans localisation et l’activation spatio-temporel d’Aurora B en créant un site d’ancrage (phosphorylation de l’Histone H3 sur la Thr3) sur les chromosomes et notamment aux centromères en première partie de mitose. Une perte d’activité de l’Haspine s’accompagne irrémédiablement d’erreurs dans l'alignement des chromosomes, la cohésion centromérique et l'intégrité des fuseaux mitotiques. Ces fonctions en fait une cible thérapeutique
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Lerner, Jonathan. "Caractérisation de l’effet de mutations MODY sur la fonction de bookmarking de HNF1beta." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T064/document.

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HNF1beta est un facteur de transcription homeobox, dont les mutations sont fréquemment rencontrées chez des patients atteints d’anomalies congénitales du rein et du tractus urinaire (Congenital Abnomalities of the Kidney and the Urogenital Tract, CAKUT). HNF1beta est également impliqué dans le diabète de type Maturity Onset Diabetes of the Young 5 (MODY5). Le laboratoire d’accueil a démontré que HNF1beta était impliqué dans un mécanisme épigénétique, le Bookmarking, nécessaire à la réexpression post-mitotique de ses gènes cibles. En particulier, des expériences de vidéo-microscopie ont montré
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Reynaud, Florie. "Rôle de la Sémaphorine 3B dans l’orientation des divisions des progéniteurs au cours de la neurogenèse chez les vertébrés." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1320/document.

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Au cours de la mitose, la ségrégation des chromatides, la partition du matériel cytoplasmique entre cellules filles et leur position relative se fait selon un plan qui est préfiguré par la plaque métaphasique. Ainsi, l'orientation de ce plan est un processus crucial pour le contrôle du destin des cellules, pour la morphogenèse durant l'embryogenèse et pour l'homéostasie tissulaire. Jusqu'à aujourd'hui, les mécanismes intrinsèques impliqués dans le positionnement du plan de division ont reçu beaucoup d'attention. En revanche, peu d'études ont exploré l'implication de signaux extracellulaires da
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Gharbi, Ayachi Aicha. "Identification et caractérisation des premiers substrats de la protéine kinase Greatwall et étude de leur implication au cours du cycle cellulaire." Thesis, Montpellier 2, 2013. http://www.theses.fr/2013MON20133.

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Au cours de la division cellulaire, l'information génétique doit être transmise de façon précise et identique de la cellule mère aux cellules filles. Le génome est répliqué au cours de la phase S tandis que la distribution des deux copies entre les cellules filles se fait au cours de la mitose. L'initiation et le maintien de la mitose nécessite un équilibre contrôlé entre les activités des kinases et des phosphatases. La protéine kinase Greatwall est requise pour l'entrée et le maintien de la mitose à travers l'inhibition de la PP2A, la principale phosphatase qui déphosphoryle les substrats du
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Ducháček, Ladislav. "Mitosis." Master's thesis, Vysoké učení technické v Brně. Fakulta výtvarných umění, 2016. http://www.nusl.cz/ntk/nusl-240615.

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Mitosis diploma work is figurative sculpture created by duplication statues. These duplicates to form pairs at each mitotic bind. Couples are composed into complex system, and thus form a spherical object. Against the background of this work is to introduce perspective on the human population and its culture as an independent organic whole.
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Goutte-Gattat, Damien. "Etude des fonctions mitotiques du domaine amino-terminal de CENP-A." Thesis, Grenoble, 2011. http://www.theses.fr/2011GRENV079/document.

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Le variant d'histone CENP-A est le facteur responsable de la détermination épigéné- tique du centromère. Il permet le recrutement de nombreuses protéines centromériques, et constitue ainsi la brique fondatrice du kinétochore. Il possède un domaine amino-terminal non structuré dont la fonction précise reste encore à élucider, bien qu'il soit déjà établi chez certaines espèces que ce domaine est requis pour le bon fonctionnement du cen- tromère et conséquemment le bon déroulement de la mitose. Nous avons construit des lignées cellulaires humaines exprimant stablement diverses formes mutantes de
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Books on the topic "Mitosom"

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Mitosis: Methods and protocols. Humana Press, 2014.

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Ohana, David. ha-Mitos shel Niyobeh: Etiḳah ṿe-alimut ve-mitosim bene zemanenu. ha-Ḳibuts ha-meʼuḥad be-shituf ʻim Universiṭat Ben Guryon ba-Negev, 2010.

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McAinsh, Andrew D., ed. Mitosis. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-993-2.

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Sharp, David J., ed. Mitosis. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0329-0.

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Bowen, I. D. Mitosis and apoptosis: Matters of life and death. Chapman & Hall, 1998.

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Maureen, Bowen Sandra, and Jones A. H, eds. Mitosis and apoptosis: Matters of life and death. Chapman & Hall, 1998.

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Gelili, Tamah. Mitosim shiḳriyim lo metim-- (ṿe-ḥaval). Ṭeraḳlin, 1996.

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Oren, Yosef. Nituts mitosim ba-siporet ha-Yiśreʼelit. Yaḥad, 2012.

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Hydrogenosomes and Mitosomes. Springer, 2008.

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Sarosh, Minal. Mitosis & other poems. Writers Workshop, 1992.

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Book chapters on the topic "Mitosom"

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Preston, Terence M., Conrad A. King, and Jeremy S. Hyams. "Mitosis." In The Cytoskeleton and Cell Motility. Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0393-7_4.

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Stauffer, Sarah, Aaron Gardner, Dewi Ayu Kencana Ungu, Ainara López-Córdoba, and Matthias Heim. "Mitosis." In Labster Virtual Lab Experiments: Basic Biology. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-57996-1_2.

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Santra, Sangita. "Mitosis." In Encyclopedia of Animal Cognition and Behavior. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-47829-6_507-1.

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Preston, Terence M., Conrad A. King, and Jeremy S. Hyams. "Mitosis." In The Cytoskeleton and Cell Motility. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4615-8010-2_4.

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Gooch, Jan W. "Mitosis." In Encyclopedic Dictionary of Polymers. Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_14241.

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Ciliberto, Andrea, and Rosella Visintin. "Mitosis." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_13.

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Hangay, George, Susan V. Gruner, F. W. Howard, et al. "Mitosis." In Encyclopedia of Entomology. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_4649.

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Mehlhorn, Heinz. "Mitosomes." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_4759.

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Mehlhorn, Heinz. "Mitosomes." In Encyclopedia of Parasitology. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_4759-1.

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Arnemann, J. "Mitose." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_3532-1.

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Conference papers on the topic "Mitosom"

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Quiñones, Carlos García, Carlos Madriles, Jesús Sánchez, Pedro Marcuello, Antonio González, and Dean M. Tullsen. "Mitosis compiler." In the 2005 ACM SIGPLAN conference. ACM Press, 2005. http://dx.doi.org/10.1145/1065010.1065043.

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Zerhouni, Erwan, David Lanyi, Matheus Viana, and Maria Gabrani. "Wide residual networks for mitosis detection." In 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017). IEEE, 2017. http://dx.doi.org/10.1109/isbi.2017.7950667.

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Sotiriadis, Paul P., and Robert W. Newcomb. "Model reference circuits for mitosis control." In 2009 17th Mediterranean Conference on Control and Automation (MED). IEEE, 2009. http://dx.doi.org/10.1109/med.2009.5164602.

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Paul, Angshuman, and Dipti Prasad Mukherjee. "Enhanced Random Forest for Mitosis Detection." In the 2014 Indian Conference. ACM Press, 2014. http://dx.doi.org/10.1145/2683483.2683569.

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Chen, Hao, Xi Wang, and Pheng Ann Heng. "Automated mitosis detection with deep regression networks." In 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016). IEEE, 2016. http://dx.doi.org/10.1109/isbi.2016.7493482.

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Dodballapur, Veena, Yang Song, Heng Huang, Mei Chen, Wojciech Chrzanowski, and Weidong Cai. "Mask-Driven Mitosis Detection In Histopathology Images." In 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI). IEEE, 2019. http://dx.doi.org/10.1109/isbi.2019.8759164.

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Lichen Liang, Xiaobo Zhou, Fuhai Li, Stephen TC Wong, Jeremy Huckins, and Randy W. King. "Mitosis cell identification with conditional random fields." In 2007 IEEE/NIH Life Science Systems and Applications Workshop. IEEE, 2007. http://dx.doi.org/10.1109/lssa.2007.4400872.

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Siva, Parthipan, G. Wayne Brodland, and David Clausi. "Automated Detection of Mitosis in Embryonic Tissues." In >Fourth Canadian Conference on Computer and Robot Vision. IEEE, 2007. http://dx.doi.org/10.1109/crv.2007.11.

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Abdulkareem, Mohammed, MD Samiul Islam, Anas Dheyab Aljoubory, and Zhou Nuoya. "Deep Fully Convolutional Networks for Mitosis Detection." In ICRCA 2019: 2019 The 4th International Conference on Robotics, Control and Automation. ACM, 2019. http://dx.doi.org/10.1145/3351180.3351213.

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Solanki, Meetal. "Phasing Out Fluorescence: Quantifying Mitosis Label-free." In European Light Microscopy Initiative 2021. Royal Microscopical Society, 2021. http://dx.doi.org/10.22443/rms.elmi2021.2.

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Reports on the topic "Mitosom"

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Joukov, Vladimir. The Role of BRCA1/BARD1 Heterodimers in the Mitosis-Interphase Transition. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada471801.

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Cortés-Castillo, Denisse Viviana, Blanca Catalina Albarracín, and María Angélica Cardozo. Mitos y realidades de la dimensión ambiental. Universidad Nacional Abierta y a Distancia, 2020. http://dx.doi.org/10.22490/ecapma.4088.

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El tema ambiental en Colombia ha ocupado un renglón relevante en el país desde hace varias décadas, situación que ha permeado a la comunidad académica. Esto ha resultado en la creación de programas cuya afinidad ha generado confusión sobre el alcance de sus profesionales y la distancia disciplinar entre los mismos. Con el propósito de abordar este y otros temas, desde la Cadena Ambiental de la Escuela de Ciencias Agrícolas, Pecuarias y del Medio Ambiente – ECAPMA, se desarrolló un conversatorio titulado “Mitos y realidades de la dimensión ambiental” que reunió a seis (6) expertos de las áreas
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Núñez, Anamaría, Adriana Loeff, Jovana Garzón Lasso, and Lucía Franco. Romper mitos y tabúes sobre la higiene menstrual. Inter-American Development Bank, 2018. http://dx.doi.org/10.18235/0001162.

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Chang, Long-Sheng. The Role of Drosophila Merlin in the Control of Mitosis Exit and Development. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada488249.

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Chang, Long-Sheng. The Role of Drosophila Merlin in the Control of Mitosis Exit and Development. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada460492.

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Keck, Jamie M., and Steve I. Reed. The Effects of Deregulated Cyclin Expression in Mitosis. A Role in Breast Tumorigenesis. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada469549.

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7

Keck, Jamie M., and Steven I. Reed. The Effects of Deregulated Cyclin E Expression in Mitosis: A Role in Breast Tumorigenesis. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada443699.

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8

Keck, Jamie M. The Effects of Deregulated Cyclin E Expression in Mitosis: A Role in Breast Tumorigenesis. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada425602.

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9

Miller, Stephanie. Mitosis-Specific Negative Regulation of EGF-Receptor in Breast Cancer: Molecular Mechanisms, Biological Significance and Therapeutic Application. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada398100.

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10

Lin, Shiaw-Yih. Mitosis-Specific Negative Regulation of EGF-Receptor in Breast Cancer: Molecular Mechanisms, Biological Significance and Therapeutic Application. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada390715.

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