Academic literature on the topic 'Mitraginina'

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Journal articles on the topic "Mitraginina"

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Setiawansyah, Arif, Gita Susanti, Nurul Hidayati, et al. "Telaah Potensi Antivirus Mitraginin terhadap Protease 3CLpro SARS-CoV-2 dengan Pendekatan Molecular Docking." Sinteza 4, no. 2 (2024): 65–73. http://dx.doi.org/10.29408/sinteza.v4i2.25634.

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SARS-CoV-2 is a novel coronavirus identified as a major caused of COVID-19. COVID-19 can be prevented and managed by preventing the SARS-CoV-2 infection through inhibition of SARS-CoV-2 main protease. Mitragynine is one of the major compounds found in Mitragyna speciosa leaves that has the potential to be developed as an anti-COVID-19 agent. This research was implemented to evaluate that potential by observing the molecular interaction of mitragynine with the essential amino acid residues of SARS-CoV-2 3CLpro. The study was undertaken by in silico method via molecular docking approach using Au
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Nugraha, Widia Indri, Robiyanto Robiyanto, and Sri Luliana. "Antinociceptive Activity of Aqueous Fraction of Kratom Leaves Mitragyna speciosa Korth.) on Male Swiss Albino Mice." Majalah Obat Tradisional 23, no. 2 (2018): 91. http://dx.doi.org/10.22146/mot.32085.

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Kratom (Mitragyna speciosa Korth.) has been known to have an analgesic opioid effect (antinociceptive). The major compound of kratom leaf is mitraginin, which has strong affinity on opioid receptor. The aim of this research is to prove antinociceptive effect of aqueous fraction of kratom leaf and its effective dose. The simplicia of kratom leaf was extracted with methanol 96%. Methanol extract fractioned with n-hexane, dichloromethane, ethyl acetate, and aquadest. This research used hot plate method on male Swiss Albino mice. The subject divided to 5 groups, negative control group, morphine 5,
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Djunet, Nur Aini Aini Djunet. "SCOOPING REVIEW: KEMATIAN KARENA KRATOM." Jurnal Forensik dan Medikolegal Indonesia 5, no. 2 (2024): 473. https://doi.org/10.20884/1.jfmi.2024.5.2.12240.

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Latar Belakang: Kratom adalah tanaman famili kopi yang tumbuh subur di Asia Tenggara. Daun kratom tinggi dengan alkaloid mitraginin yang bersifat stimulansia. Sampai saat ini kratom dilegalkan bahkan bernilai ekspor tinggi di Indonesia, berbeda dengan Malaysia dan Thailand yang telah melarang peredaran kratom. Beberapa studi melaporkan kasus toksisitas kratom namun data kematian terkait kratom masih terbatas. Tujuan: Untuk mengetahui data kematian dengan riwayat penggunaan kratom. Metode: Pencarian artikel yang terbit pada lima tahun terakhir secara sistematis pada tujuh database artikel. Berd
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Nagy, H., L. Buftea, L. Domokos, and A. Mihai. "Spice plants induced psychosis-case presentation." European Psychiatry 26, S2 (2011): 30. http://dx.doi.org/10.1016/s0924-9338(11)71741-2.

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Spice shops, selling ethnobotanical plants like Salvia divinorum, Mitragina speciosa, Amanita muscaria and others, have become very numerous in Romania, first of all because they are legal, second of all because more and more young people are tempted to experiment new sensations. These plants can cause different psychiatric illnesses and associating theme with alcohol or drugs can also be fatal.Our objective was to present the case of a 25 year old male patient consulted at emergency service, and admitted in our department, presenting psychomotor agitation, anxiety and the specific elements of
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Elsa, Livia. "Pengembangan Metode Isolasi dan Identifikasi Mitragynine dalam Daun Kratom (Mitragyna speciosa)." Jurnal Biosains Pascasarjana 18, no. 3 (2016): 191. http://dx.doi.org/10.20473/jbp.v18i3.2016.191-202.

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Abstrak Kratom (Mitragina speciosa) merupakan tanaman herbal asal Indonesia. Daun kratom memiliki banyak manfaat sebagai obat herbal seperti obat demam, diare, dan penghilang nyeri. Efek sedatif dan stimulan pada sistem syaraf pusat merupakan efek samping daun Kratom. Harga yang murah dan kemudahan dalam memperoleh daun Kratom menjadi penyebabkan utama daun Kratom banyak disalahgunakan sebagai penganti narkotika terlarang lainnya. Daun kratom masuk kedalam new psychoactive substances (NPS) atau narkotika jenis baru karena memiliki efek ketergantungan dan bertindak seperti opioid lainnya sepert
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Kurdil, N. V., A. E. Podrushnyak, M. L. Zinovieva, H. I. Petrashenko, U. V. Karpiuk, and N. P. Kovalska. "On the relevance of toxicological and hygienic assessment and market regulation of herbal dietary supplements made from Mitragyna speciosa Korth (Rubiaceae family)." One Health and Nutrition Problems of Ukraine 55, no. 2 (2021): 30–43. http://dx.doi.org/10.33273/2663-9726-2021-55-2-30-43.

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Ukraine today does not regulate the sale of products made of Kratom (Mitragyna speciosa Korth. (from the family Rubiaceae) and does not take measures to control the quality and safety of this product, despite its rapid spread throughout the country. Аim of the Work is to summarize the results of scientific research on the toxicity of alternative opioids contained in Mitragyna speciosa and combined products based on them. Material and methods. Reports from the World Health Organization (WHO), the European Monitoring Center for Drugs and Drug Addiction (EMCDDA), the United Nations Office on Drug
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Csorba, A., L. Domokos, H. Nagy, D. Cosman, and A. Mihai. "Medical implication of intoxication with legal spice plants in Romania." European Psychiatry 26, S2 (2011): 19. http://dx.doi.org/10.1016/s0924-9338(11)71730-8.

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In lasts years in Romania a new challenge for the young appears: the legal spice shops. The promotions of using these substances include the promising like: relaxation, happiness, energy, sexual performance, increasing of social abilities.Aimsevaluation of medical consequences of intoxication with spice plants (Bonsai, “magic charge”, “mariciuca”, Salvia divinorum, Mitragina speciosa and others). The precise composition of substance used was not clear but the known drugs were excluded. Material and method: all patients with diagnosis of intoxication of spice plants, admitted for at least 24 ho
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Alowanou, GG, AP Olounlade, EVB Azando, VFGN Dedehou, FD Daga, and M. Hounzangbe-adote. "A review of Bridelia ferruginea, Combretum glutinosum and Mitragina inermis plants used in zootherapeutic remedies in West Africa: historical origins, current uses and implications for conservation." Journal of Applied Biosciences 87, no. 1 (2015): 8003. http://dx.doi.org/10.4314/jab.v87i1.4.

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Angyal, Péter, Szilárd Varga, and Tibor Soós. "Az opioidkrízis egy lehetséges megoldása: új típusú fájdalomcsillapítók fejlesztése." Scientia et Securitas, November 11, 2024. http://dx.doi.org/10.1556/112.2024.00175.

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Az opioidválság hatására kiemelten fontos kutatási iránnyá vált az új fájdalomcsillapítók fejlesztése, amelyek a korábbiaknál kedvezőbb mellékhatásprofillal rendelkeznek. A probléma lehetséges megoldását ismét a természet inspirálta: a kratom növény egy metabolitja, a mitraginin-pszeudoindoxil, amelynek gyógyszeripari fejlesztését akadályozza a vegyülethez való korlátozott hozzáférhetőség. A Kooperatív Doktori Program keretében megvalósítottuk e természetes vegyület, majd számos származék első totálszintézisét. Ezzel lehetőség nyílt a szerkezet–hatás összefüggéseket feltérképező biológiai vizs
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Ridwan, Ahad, Rachimi ., and Farida . "PENGGUNAAN SERBUK DAUN KRATOM (Mitragyna speciosa Korth)SEBAGAI ANESTESI DALAM PROSES TRANSPORTASI BENIH IKAN TENGADAK (Berbonymusscwanenfeldii)." Jurnal Ruaya : Jurnal Penelitian dan Kajian Ilmu Perikanan dan Kelautan 5, no. 2 (2017). http://dx.doi.org/10.29406/rya.v5i2.718.

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Transportasi benih ikan sangat berpengaruh besar dalam hal kematian massal pada ikan, hal ini dikarenakan didalam perjalanan ikan mengalami goncangan serta oksigen yang tersedia selama pengangkutan tidak mencukupi terutama di daerah yang waktu tempuhnya lama.Salahsatu usahauntukmengurangi kematian benihtengadak yang di sebabkan stress adalah dengan upaya pembiusan atau anestesi pada ikan selama transportasi. Salah satu bahan alami yang potensial digunakan sebagai anestesi alami adalah daun kratom. Kandungan utama dari daun kratom ini adalah alkaloid indol, yaitu mitraginin (66,2%) dan 7-hidrok
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Dissertations / Theses on the topic "Mitraginina"

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Meireles, Vânia Sofia de Oliveira. "Mitragyna speciosa: aspetos analíticos e toxicológicos." Master's thesis, 2017. http://hdl.handle.net/10400.6/8318.

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O presente relatório de estágio encontra-se inserido na unidade curricular Estágio Curricular do Mestrado Integrado de Ciências Farmacêuticas. Deste trabalho constam três partes: a primeira referente ao trabalho de pesquisa bibliográfica, uma revisão da literatura no âmbito da toxicidade da Mitragyna speciosa, o seu consumo como droga de abuso bem como o seu doseamento; a segunda aborda o estágio curricular realizado em farmácia comunitária e a terceira aborda o estágio curricular realizado em farmácia hospitalar. O primeiro capítulo intitula-se “Mitragyna speciosa: aspetos analíticos e toxico
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