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Dissertations / Theses on the topic 'Mixed infections of malaria'

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1

Taylor, Louise H. "Epidemiological and evolutionary consequences of mixed-genotype infections of malaria parasites." Thesis, University of Edinburgh, 1997. http://hdl.handle.net/1842/13081.

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In this thesis, three aspects of parasite life history were investigated: the trade-off between asexual growth and reproduction, the virulence of infections and the sex ratio of transmission stages. All three, and the frequency of mixed infections in a population itself, are fundamentally linked to the transmission and pathology of malaria, the reduction of which is the aim of all current control programmes. An experimental system of the rodent malaria <I>Plasmodium chabaudi </I>in mice allows controlled mixed-infections of distinct clones to be initiated and was used to test theoretical predi
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2

Ramiro, Ricardo Filipe Serrote. "Evolution and ecology of malaria parasites : from mating to mixed‐species infections." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/7542.

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Despite over a century of research, malaria parasites (Plasmodium) still remain a major cause of mortality and morbidity worldwide. In recent years, the application of theoretical principles from ecology and evolutionary biology to the study of these parasites has started to provide insight into variety of fundamental subjects from the evolution of virulence to the facultative strategies (i.e. phenotypic plasticity) that parasites use to maximize their transmission. It is now becoming increasingly clear that to understand and predict population level patterns of virulence and transmission, the
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3

Timms, Rebecca. "The ecology and evolution of virulence in mixed infections of malaria parasites." Thesis, University of Edinburgh, 2001. http://hdl.handle.net/1842/13132.

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This thesis focuses on the determinants of virulence in single and mixed-clone malaria infections, and the consequent impact of these infections for host- and parasite-fitness. Controlled experiments were conducted using a rodent model of malarial disease, <i>Plasmodium chabaudi. </i>Mice were infected with precise numbers of virulent and avirulent parasites. In the mixtures, known ratios of two clones that differed in virulence were used. Virulence was quantified in terms of host morbidity and mortality. Experiments investigating how virulence is determined in mixtures revealed that both the
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4

Albuquerque, C. M. R. "The immune response of Aedes aegypti and the effect of mixed Plasmodium gallinaceum and Brugia pahangi infections on parasite development." Thesis, Keele University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282632.

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5

Milet, Jacqueline. "Étude de la composante génétique de la variabilité des infections palustres simples : Approche génome entier dans deux cohortes de jeunes enfants au Bénin First Genome-Wide Association Study of Non-Severe Malaria in Two Birth Cohorts in Benin Mixed logistic regression in Genome-Wide Association Studies." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASR013.

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Malgré les moyens importants de prévention et de lutte mis en place ces dernières années, le paludisme reste dévastateur avec près d’un demi-million de décès par an (405 000 en 2018, d'après le dernier rapport de l'OMS). Le rôle clé joué par les facteurs génétiques de l’hôte dans la susceptibilité et la sévérité de la maladie est admis aujourd'hui. Cependant, les bases moléculaires de la sensibilité/résistance au paludisme restent encore mal connues. Ces dix dernières années, les efforts de recherches pour l’identification de gènes impliqués dans la sensibilité au paludisme à P. falciparum se
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6

Cunnington, Aubrey Justin. "Malaria and susceptibility to other infections." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2012. http://researchonline.lshtm.ac.uk/901045/.

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Malaria is widely perceived as immunosuppressive. Despite extensive phenomenological description, the underlying mechanisms remain poorly described. The aim of this thesis was to identify possible mechanisms by which malaria modifies host defence, and to determine the importance of these mechanisms in a translational system moving from a mouse model to human malaria. The most frequently cited immunological consequences of malaria are: suppression of vaccine responses, susceptibility to bacterial infection, susceptibility to endemic Burkitt lymphoma, and increased HIV viral load. Of these, susc
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7

Owusu-Ofori, Alex. "Transfusion-transmitted malaria and bacterial infections in a malaria endemic region." Thesis, University of Liverpool, 2012. http://livrepository.liverpool.ac.uk/6173/.

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Background and Methods: Blood transfusion saves lives and improves health but the presence of transfusion transmissible infections can have untoward consequences. When undetected, these infections can cause significant morbidity and mortality to transfusion recipients. On the other hand, a high prevalence of transfusion-transmitted infections (TTI) leading to rejection of a large proportion of donated blood can result in blood shortages and subsequent increase in mortality. Malaria and bacterial infections are transfusion transmissible but there is limited data concerning these infections in s
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8

Takehisa, Jun. "HIV Mixed Infections and Recombination." Kyoto University, 1999. http://hdl.handle.net/2433/181727.

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9

Nelson, Maria. "Host responses to malaria and bacterial co-­infections." Doctoral thesis, Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-102795.

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The two main causes of child mortality and morbidity in Africa are malaria and invasive bacterial diseases. In addition, co-infections in sub-Saharan Africa are the rule rather than the exception. However, not much is known about the host-pathogen interaction during a concomitant infection or how it affects the outcome of disease. In order to study the immunological responses during malaria and bacterial co-infections, we established a co-infection mouse model. In these studies we used two pathogenic bacteria found in malaria co-infected patients: Streptococcus pneumoniae and Relapsing fever B
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10

Kloprogge, Frank Lodewijk. "Pharmacokinetics and pharmacodynamics of antimalarial drugs in pregnant women." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:79ce1a37-3ba2-45e4-9f80-0692a66837f1.

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Malaria is the most important parasitic disease in man and it kills approximately 2,000 people each day. Pregnant women are especially vulnerable to malaria with increased incidence and mortality rates. There are indications that pregnancy alters the pharmacokinetic properties of many antimalarial drugs. This is worrisome as lower drug exposures might result in lowered efficacy and lower drug exposures can also accelerate the development and spread of resistant parasites. The aim of this research was to study the pharmacokinetics and pharmacodynamics of the most commonly used drugs for the tre
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11

Grills, Ardath White. "The complexity of Plasmodium falciparum infections in children in western Kenya /." Download the dissertation in PDF, 2006. http://www.lrc.usuhs.mil/dissertations/pdf/Grills2006.pdf.

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12

Reade, Brian. "The population dynamics of mixed pathogen infections." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.264017.

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13

Bereczky, Sándor. "Genetic diversity of Plasmodium falciparum infections : influence on protective malaria immunity /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-548-8/.

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14

Pothin, Emilie. "Modelling antibody responses to malaria blood stage infections : a novel method to estimate malaria transmission intensity from serological data." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24682.

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Infection with the Plasmodium falciparum malaria parasite results in an immune response which includes the production of antibodies against the blood-stage of infection. In recent years there has been an increase in the use of serological data to monitor malaria transmission intensity. Traditionally, EIR and parasite prevalence were the preferred tools for measuring malaria transmission intensity. Serology has been shown to be particularly useful in areas of low endemicity where traditional measures (EIR and parasite prevalence) are problematic. Transmission intensity in this case is usually d
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15

Vojvodic, Svjetlana, Jacobus Boomsma, Jorgen Eilenberg, and Annette Jensen. "Virulence of mixed fungal infections in honey bee brood." BioMed Central, 2012. http://hdl.handle.net/10150/610138.

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INTRODUCTION:Honey bees, Apis mellifera, have a diverse community of pathogens. Previous research has mostly focused on bacterial brood diseases of high virulence, but milder diseases caused by fungal pathogens have recently attracted more attention. This interest has been triggered by partial evidence that co-infection with multiple pathogens has the potential to accelerate honey bee mortality. In the present study we tested whether co-infection with closely related fungal brood-pathogen species that are either specialists or non-specialist results in higher host mortality than infections wit
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16

Distiller, G. B. "Nonlinear mixed effects modeling of gametocyte carriage in patients with uncomplicated malaria." Master's thesis, University of Cape Town, 2007. http://hdl.handle.net/11427/4378.

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17

Homenauth, Esha. "Evaluating Multi-level Risk Factors for Malaria and Arboviral Infections in Regions of Tanzania." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35633.

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Vector-borne diseases, such as those transmitted by mosquitoes, pose a significant public health concern in many countries worldwide. In this thesis, I explored the role of a number of risk factors defined at multiple scales on vector-borne disease prevalence, focusing on malaria and arboviral infections in several regions of North-Eastern Tanzania, with the principal aim of improving the overall diagnosis of febrile illness in this region. First, I investigated the influence of household-wealth on prevalence of malaria and arboviral infections using principal component analysis (PCA), and t
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18

Stead, Michael Craig. "Detection of mixed Mycobacterium tuberculosis infections in South African TB Patients." Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/2720.

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Recently, the widely accepted theory that TB disease resulted from one infecting M. tuberculosis strain leading to heightened immune protection against subsequent infections, has been revised. Epidemiological studies and the advances in molecular genotyping techniques have highlighted the rapidly frequent isolation of several different M. tuberculosis strain lineages in single disease episodes, often with differing drug susceptibilities. This has important implications on drug susceptibility testing and the treatment of patients. It has also highlighted the relative contributions of exogenous
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19

Lundqvist, Jenny. "Malaria and relapsing fever Borrelia : interactions and potential therapy." Doctoral thesis, Umeå universitet, Molekylärbiologi (Medicinska fakulteten), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-21845.

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Infectious diseases such as malaria and relapsing fever borreliosis (RF), cause severe human mortality and morbidity in developing countries. Malaria, caused by Plasmodium spp. parasites, is estimated by the World Health Organization to cause 1.5-2.7 million deaths annually. RF, caused by Borrelia spirochetes, has the highest prevalence described for any bacterial disease in Africa, with infection outcomes ranging from asymptomatic to fatal. RF borreliosis manifests in humans as a recurring fever and with other symptoms very similar to those of malaria. RF borreliosis has been regarded as a tr
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20

Donati, Daria. "Malaria, B lymphocytes and Epstein-Barr virus : emerging concepts on Burkitt's lymphoma pathogenesis /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-403-1/.

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21

Al-Ankari, Abdul-Rahman Sultan. "Studies on avian mycoplasmas in mixed infections and strain differentiation of Mycoplasma iowae." Thesis, University of Liverpool, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333561.

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22

McNaughton, Anna Lukats. "Mixed genotype hepatitis C virus infections : incidence in Scotland and methods for detection." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/7848/.

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The diagnosis of mixed genotype hepatitis C virus (HCV) infection is rare and information on incidence in the UK, where genotypes 1a and 3 are the most prevalent, is sparse. Considerable variations in the efficacies of direct-acting antivirals (DAAs) for the HCV genotypes have been documented and the ability of DAAs to treat mixed genotype HCV infections remains unclear, with the possibility that genotype switching may occur. In order to estimate the prevalence of mixed genotype 1a/3 infections in Scotland, a cohort of 512 samples was compiled and then screened using a genotype-specific nested
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23

Knox, Elizabeth. "Mixed infections of maize dwarf mosaic virus and cucumber mosaic virus in maize." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/21898.

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Bibliography : pages 218-230.<br>Maize plants collected in three geographically distinct regions of South Africa were found to be doubly infected with maize dwarf mosaic (MDMV) and cucumber mosaic virus (CMV). A mixed infection of these two viruses could be maintained in maize plants grown under laboratory conditions. The possibility of synergism or of an interference mechanism between MDMV and CMV in dual infections was investigated and it was found that prior infection with CMV interfered with subsequent infection by MDMV. MDMV and CMV were shown to be non-persistently transmitted by Myzus p
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24

Ansumana, Rashid. "Tiered laboratory analyses for common infections to characterize febrile morbidity not related to malaria in Sierra Leone." Thesis, University of Liverpool, 2015. http://livrepository.liverpool.ac.uk/2035608/.

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In tropical Africa, fever is commonly associated with malaria. However, there are many other illnesses presenting with fever. Non-malaria febrile illnesses (NMFIs) may be attributable to multiple etiologic agents including viral, bacterial and parasitic infections in malaria-endemic resource-poor countries. NMFIs pose challenges to peripheral health systems such that they are clinically under-diagnosed while malaria remains over-diagnosed. Misdiagnoses of a febrile condition may lead to wrong prescription that delays treatment and increases expenditure on health-care and also leads to increase
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25

Williams, J. E. O. "The prevalence and importance of malaria infections during pregnancy not detected by microscopy or rapid diagnostic testing." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2018. http://researchonline.lshtm.ac.uk/4647550/.

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With the advent of rapid diagnostic tests (RDT) for malaria detection, parasitological confirmation of malaria diagnoses has become more readily accessible and increasingly more affordable. However, questions are being asked about how useful they are in screening programmes, particularly for pregnant women who very often may harbour placental malaria infections which may not be detected by peripheral blood smear microscopy. It is also necessary to examine how many malaria infections go undetected by RDTs and whether such undetected infections have any negative consequences for women who carry
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26

Lalremruata, Albert [Verfasser]. "Development of molecular methods for screening Plasmodium infections : New diagnostics for the era of malaria elimination / Albert Lalremruata." Tübingen : Universitätsbibliothek Tübingen, 2021. http://d-nb.info/1226756301/34.

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27

Surrao, Leanna. "The optimization of loop-mediated isothermal amplification (LAMP) as a diagnostic tool for low-density, asymptomatic malaria infections." Thesis, Federation University Australia, 2020. http://researchonline.federation.edu.au/vital/access/HandleResolver/1959.17/172068.

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Current diagnostic tools for malaria lack the sensitivity to identify individuals with low-density infections. Asymptomatic low-density infections are common in malaria endemic regions and these individuals provide an important reservoir of infection that enables transmission to mosquitoes. Failure to detect these individuals threatens the global health goal of malaria elimination. Loop-mediated isothermal amplification (LAMP) is a technique to amplify DNA and has the potential to diagnose these individuals. The LAMP assay was assessed in a field study in rural Vietnam. 5421 samples were colle
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28

Wildig, James William. "The contribution of Human parvovirus B19 infection to cases of severe anaemia among young children in Malaria endemic areas." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28139.

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Human Parvovirus BI9 (BI9) is a common virus with worldwide distribution. Acute infection causes cessation of erythropoiesis for 5 - 7 days. This viral suppression of bone marrow leads to a decrease in the haemoglobin level of the infected individual. Cases of severe anaemia induced by B19 infection have been described in people with underlying haematological disorders such as Sickle Cell disease, as well as children with malaria and iron deficiency. Among young children in malaria endemic areas anaemia is extremely common. The aetiology of this is complex with multiple contributing fa
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Sripan, Patumrat. "The Mechanisms And Timing Of Mother To Child Transmission Of HIV Using Model Based Approaches Integrating Prior Information From Historical Data." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS092.

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Grâce aux combinaison d’antirétroviraux (ART), le taux de transmission mère-enfant (TME) du Virus de l’Immunodéficience Humaine VIH est maintenant réduit à moins de 1%. Des progrès restent néanmoins à faire, en particuliers chez les femmes débutant tardivement leurs consultations prénatales. Mais l’évaluation de nouvelles stratégies ART pour la prévention de la TME (PTME) devient de plus en plus complexe à cause des exigences statistiques liées au fait que les transmissions sont rares. Dés lors, il devient crucial de modéliser l’efficacité des ART sur la charge virale (CV) et la transmission.
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Wendler, Jason Patrick. "Accessing complex genomic variation in Plasmodium falciparum natural infections." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:c9f1ea37-7005-4757-a869-7eba82406a26.

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Genetic polymorphism in Plasmodium falciparum is a considerable obstacle to malaria intervention. Parasites have repeatedly evolved to overcome every front-line antimalarial deployed throughout history, and artemisinin resistant populations are expanding in Southeast Asia. Promising vaccine candidates routinely fail when challenged by the genetic diversity of natural parasite populations, and a recent trial using a blood-stage antigen showed immunity was allele specific. Modern sequencing technologies have revolutionized our understanding of parasite genomics and population genetics by providi
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Solofoharivelo, Marie Chrystine. "Molecular Characterizations of Transgenic Nicotiana Benthamiana Plants Resistant to Red Clover Necrotic Mosaic Virus and Effects of Mixed Infections with Potato Virus Y on RNAi-Mediated Resistance." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/194799.

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Engineered resistance mediated by RNA interference to control viral diseases in plants has shown great promise. However, the discovery that most known plant viruses encode RNAi suppressors which interfere with RNAi raised the issue to whether this type of engineered resistance can be durable in the presence of heterologous viruses in mixed infection. The overall goal of this study was to investigate the mechanism of suppression of RNAi-mediated resistance in transgenic plants in the presence of a virus carrying a strong suppressor of RNAi. Nicotiana benthamiana plants were transformed with a
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32

van, der Merwe Marcel. "Yeast-baculovirus synergism: investigating mixed infections for improved management of the false codling moth, Thaumatotibia leucotreta." Thesis, Rhodes University, 2018. http://hdl.handle.net/10962/62963.

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33

Sharma, Bikram. "Influence of co-infection on the infection density of Borrelia burgdorferi and Ixodes scapularis endosymbiont in Ixodes scapularis ticks." Muncie, Ind. : Ball State University, 2009. http://cardinalscholar.bsu.edu/619.

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34

Cellier-Holzem, Elise. "Ecologie évolutive de la malaria aviaire : approches expérimentales des relations entre Plasmodium relictum et le canari domestique." Phd thesis, Université de Bourgogne, 2010. http://tel.archives-ouvertes.fr/tel-00665065.

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L'étude des interactions hôtes/parasites est actuellement un thème de recherche incontournable des sciences de l'évolution. Une des questions majeures soulevée par ces études est de comprendre pourquoi certains parasites provoquent des maladies mortelles, alors que d'autres restent relativement bénins pour leurs hôtes. Dans ce défi que tentent de relever les biologistes de l'évolution mais également les sciences médicales, nous avons choisi de nous intéresser à la malaria aviaire, et plus précisément à son représentant le plus commun dans les populations naturelles d'oiseaux : Plasmodium relic
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35

Howard, N. "Malaria control for Afghans in Pakistan and Afghanistan (1990-2005) : a mixed-methods assessment considering effectiveness, efficiency, equity, and humanity." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2017. http://researchonline.lshtm.ac.uk/4646629/.

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Increased global attention and funding has provided opportunities to strengthen malaria control. One cross-border control programme researched a range of prevention and treatment interventions over twenty years to reduce the malaria burden for Afghans in Pakistan and Afghanistan. Malaria in these areas is unstable and seasonal. Primary vectors include Anopheles culicifacies, An. fluviatilis, and An. stephensi. Objectives were to evaluate malaria control interventions in refugee settlements in Northwest Pakistan and returnee settlements in Eastern Afghanistan. Findings offer lessons for program
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Alnaji, Fadi. "Isolation and analysis of recombinants from mixed virus infections of poliovirus using next generation sequencing (NGS) and bioinformatics." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/98260/.

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RNA virus recombination is a key evolutionary mechanism and a driver of genetic diversity. In recent studies using an in vitro “CRE-REP” assay involving replication-compromised parental genomes, recombination was shown to be a biphasic process involving an initial imprecise crossover event which was followed by a resolution process that resulted in the formation of genome-length recombinants (Lowry K. et al 2014). We have extended this study to investigate recombination during dual infection by unmodified parental viruses in the absence of selection. Recombinants were generated by co-infecting
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Adjakossa, Eric Houngla. "Analyse longitudinale multivariée par modèles mixtes et application à l'épidémie de la malaria." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066014.

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Dans cette thèse, nous nous sommes focalisés sur le modèle statistique linéaire à effets mixtes. Nous nous sommes d'abord intéressés à l'estimation consistante des paramètres du modèle dans sa version multidimensionnelle, puis à de la sélection d'effets fixes en dimension un. En ce qui concerne l'estimation des paramètres du modèle linéaire à effets mixtes multidimensionnel, nous avons proposé des estimateurs du maximum de vraisemblance par utilisation de l'algorithme EM, mais avec des expressions plus générales que celles de la littérature classique, permettant d'analyser non seulement des do
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Jukes, Michael David. "Baculovirus synergism: investigating mixed alphabaculovirus and betabaculovirus infections in the false codling moth, thaumatotibia leucotreta, for improved pest control." Thesis, Rhodes University, 2018. http://hdl.handle.net/10962/61797.

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Baculovirus based biopesticides are an effective and environmentally friendly approach for the control of agriculturally important insect pests. The false codling moth (FCM), Thaumatotibia leucotreta (Meyrick) (Lepidoptera: Tortricidae), is indigenous to southern Africa and is a major pest of citrus crops. This moth poses a serious risk to export of fruit to foreign markets and the control of this pest is therefore imperative. The Cryptophlebia leucotreta granulovirus (CrleGV) has been commercially formulated into the products Cryptogran™ and Cryptex®. These products have been used successfull
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Green, Shana M. "Mixed Method Study of Condom Use among Emerging Adults with New Sex Partners Met Online or Offline." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6850.

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Introduction: Emerging adults (young people age 18 to 29) are increasingly using the Internet to seek sex partners, with over 30% having tried an online or mobile dating site. As more emerging adults use dating and sex-seeking websites (DSP) for their love and sexual pursuits, it is imperative to understand how DSPs contribute to HIV/STI risk. Objectives: The objectives of this research were accomplished by pursuing the following specific aims: Aim 1. To systematically review and quantitatively synthesize evidence from published findings to determine the association between condom use and meet
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Méndez, Sheyla Inés Castillo. "Estudo dos mecanismos envolvidos na ativação policlonal dos linfócitos B durante a fase aguda da infecção pelo Plasmodium chabaudi AS." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-26102011-170611/.

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A resposta imune ao P. chabaudi se caracteriza pela ativação policlonal de linfócitos B na fase aguda da doença, que resulta em uma intensa produção de anticorpos IgM e IgG de baixa afinidade e autoanticorpos. Apesar de esses anticorpos contribuírem para o controle da infecção, pode retardar a geração de anticorpos de alta afinidade que garantem a destruição dos parasitas e a proteção contra infecções subseqüentes. O nosso objetivo foi caracterizar os mecanismos envolvidos na ativação policlonal dos linfócitos B na infecção pelo P. chabaudi AS. Os nossos resultados mostraram que a cooperação T
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Alqahtani, Amani Salem. "The risk of respiratory tract infections among Australian Hajj pilgrims and the effective use of preventive health measures during Hajj: a mixed method study." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/17764.

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As the world’s largest annual mass gathering, Hajj presents a major challenge to disease control in Saudi Arabia, as increasingly more and more people travel each year to commemorate the pilgrimage, but also internationally with the risk of pilgrims importing infectious diseases into their home countries when they return. Respiratory tract infections, including influenza and pneumonia, are the leading health risks at Hajj. Emerging infections like Middle East respiratory syndrome coronavirus (MERS-CoV) pose additional threats to disease control. Various preventive health measures have been int
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Avelar, Ana Sofia. "Single and Mixed Infections of Plant RNA and DNA Viruses are Prevalent in Commercial Sweet Potato in Honduras and Guatemala." Thesis, The University of Arizona, 2015. http://hdl.handle.net/10150/578609.

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Sweet potato is one of the 15 most important food crops worldwide. At least 30 different virus species, belonging to different taxonomic groups affect sweet potato. Little is known about the viruses present in sweet potato crops in Central America, which is the primary origin of sweet potato. The objective of this study was to design and implement primers for use in polymerase chain reaction (PCR) and Reverse transcription-PCR (RT-PCR) to identify and survey the diversity of plant viruses infecting sweet potato in Honduras and Guatemala. Primers were designed and used to amplify, clone, and se
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Pantalone, David W. "A mixed methods approach to investigate partner violence in HIV-positive outpatients /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/9156.

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44

Maloreh-Nyamekye, Theophilus. "The impact of information, education and communication (IEC) strategies in malaria prevention and control during pregnancy in Africa." Thesis, Robert Gordon University, 2013. http://hdl.handle.net/10059/842.

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Background: Malaria continues to pose a complex public health problem amongst pregnant women in Africa (Schantz-Dunn & Nour 2009; Antwi 2010), accounting for over 90% of the global malaria burden (WHO 2002; Morel et al. 2005; Schantz-Dunn & Nour 2009). However, little is known about the impact of information, education and communication (IEC) strategies in malaria prevention and control among pregnant women in Africa. Aims and Objectives: The study sought to identify: evidence of impact of IEC strategies; feasibility, appropriateness, meaningfulness and effectiveness of the IEC strategies; cha
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Chaponda, E. B. "The epidemiology of malaria, curable sexually transmitted and reproductive tract infections and their coinfection among pregnant women in a catchment area in Nchelenge District, Zambia." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2017. http://researchonline.lshtm.ac.uk/4398420/.

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Introduction: Malaria and curable sexually transmitted and reproductive tract infections (STIs/RTIs) are important causes of adverse birth outcomes (ABO) and are both prevalent in most parts of sub-Saharan Africa. From a public health perspective, control of these infections requires interventions that are part of an integrated antenatal care package. The extent to which there may be coinfection increases the importance of such an integrated approach to reduce ABO. A systematic review and meta-analysis published in 2012 showed that the prevalence of malaria and curable STIs/RTIs among antenata
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46

Fernandes, Priyanka Noel [Verfasser], and Ann-Kristin [Akademischer Betreuer] Mueller. "Differences in antigen presentation between sporozoite and parasitised-erythrocyte infections uncovers divergent mechanisms in the development of experimental cerebral malaria / Priyanka Noel Fernandes ; Betreuer: Ann-Kristin Mueller." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://d-nb.info/1180617630/34.

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47

Fernandes, Priyanka [Verfasser], and Ann-Kristin [Akademischer Betreuer] Müller. "Differences in antigen presentation between sporozoite and parasitised-erythrocyte infections uncovers divergent mechanisms in the development of experimental cerebral malaria / Priyanka Noel Fernandes ; Betreuer: Ann-Kristin Mueller." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:16-heidok-219812.

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48

Fernandes, Priyanka Noel Verfasser], and Ann-Kristin [Akademischer Betreuer] [Müller. "Differences in antigen presentation between sporozoite and parasitised-erythrocyte infections uncovers divergent mechanisms in the development of experimental cerebral malaria / Priyanka Noel Fernandes ; Betreuer: Ann-Kristin Mueller." Heidelberg : Universitätsbibliothek Heidelberg, 2016. http://d-nb.info/1180617630/34.

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49

Chan, Jennie. "Dissecting the Role of a lncRNA and Involvement of Plasmodium Infections in the Innate Immune Response: A Dissertation." eScholarship@UMMS, 2015. https://escholarship.umassmed.edu/gsbs_diss/777.

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The innate immune system is a multicomponent response governed by intricate mechanisms of induction, regulation and resolution to elicit antimicrobial defenses. In recent years, the complexity of eukaryotic transcriptomes has become the subject of intense scrutiny and curiosity. It has been established, that RNA polymerase II (RNAPII) transcribes hundreds to thousands of long noncoding RNAs (lncRNAs), often in a stimulus and cell-type specific manner. However, the functional significance of these transcripts has been particularly controversial. While the number of identified lncRNAs is growing
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50

Chan, Jennie. "Dissecting the Role of a lncRNA and Involvement of Plasmodium Infections in the Innate Immune Response: A Dissertation." eScholarship@UMMS, 2004. http://escholarship.umassmed.edu/gsbs_diss/777.

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Abstract:
The innate immune system is a multicomponent response governed by intricate mechanisms of induction, regulation and resolution to elicit antimicrobial defenses. In recent years, the complexity of eukaryotic transcriptomes has become the subject of intense scrutiny and curiosity. It has been established, that RNA polymerase II (RNAPII) transcribes hundreds to thousands of long noncoding RNAs (lncRNAs), often in a stimulus and cell-type specific manner. However, the functional significance of these transcripts has been particularly controversial. While the number of identified lncRNAs is growing
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