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Journal articles on the topic 'Mixed infections of malaria'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Singh, Upasana Shyamsunder, Nisha Siwal, Veena Pande, and Aparup Das. "Can Mixed Parasite Infections Thwart Targeted Malaria Elimination Program in India?" BioMed Research International 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/2847548.

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India is highly endemic to malaria with prevalence of all five species of human malaria parasites of Plasmodium genus. India is set for malaria elimination by 2030. Since cases of mixed Plasmodium species infections remain usually undetected but cause huge disease burden, in order to understand the distributional prevalence of both monospecies infections and mixed species infections in India, we collated published data on the differential infection incidences of the five different malaria parasites based on PCR diagnostic assay. About 11% of total cases were due to mixed species infection. Amo

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2

Nauriyal, Deepty, and Deepak Kumar. "Study of Severe Malaria Caused by Plasmodium Vivax in Comparison to Plasmodium Falciparum and Mixed Malarial Infections in Children." Biomedical and Pharmacology Journal 15, no. 3 (2022): 1597–604. http://dx.doi.org/10.13005/bpj/2498.

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Background: Malaria alone is responsible for major proportion of morbidity and mortality in children. Most cases of malaria are due to P.vivax. P.vivax has always been considered benign but recent studies and molecular studies are giving evidences towards increasing virulence and severity of P.vivax Aims and objective: Aim of this study was to observe severe malaria caused by P.vivax in comparison to Falciparum and mixed malarial infections. Other added aim was to observe for concomitant bacterial infections, how it affects clinical outcome and role of antibiotics in such cases of severe malar

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ALIFRANGIS, M., M. M. LEMNGE, R. MOON, et al. "IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children." Parasitology 119, no. 4 (1999): 337–42. http://dx.doi.org/10.1017/s0031182099004825.

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A cross-sectional sero-epidemiological study was performed in Magoda, Tanzania, an area where malaria is holoendemic. Blood samples were collected from children (1–4 years) and tested for IgG antibody reactivity against 2 recombinant protein fragments of Plasmodium falciparum Rhoptry-Associated Protein-1 (rRAP-1). The data were related to the prevalence of malarial disease and single P. falciparum or mixed Plasmodium infections. Fever ([ges ]37·5 °C) in combination with parasite densities >5000/μl were used to distinguish between children with asymptomatic malaria infections and those with

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Vera Akmilia, Anak Agung Ayu Yuli Gayatri, and Anak Agung Wiradewi Lestari. "Cerebral Malaria from a Plasmodium falciparum and Plasmodium malariae Co-Infection: A Case Report on a Diagnostic Challenge." Archives of The Medicine and Case Reports 6, no. 3 (2025): 1448–59. https://doi.org/10.37275/amcr.v6i3.779.

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Severe malaria, primarily caused by Plasmodium falciparum, is a life-threatening medical emergency. Its diagnosis can be significantly complicated by mixed-species infections, where the presence of a less virulent Plasmodium species may mask the true etiological agent of the severe disease, leading to potential delays in appropriate therapy. This report details a case of cerebral malaria where such a diagnostic challenge occurred. An 18-year-old male with a recent travel history to a malaria-endemic area in Indonesia presented with a one-day history of decreased consciousness (Glasgow Coma Sca

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Djuidje Chatue, Ide Armelle, Maximilienne Ascension Nyegue, Severin Donald Kamdem, et al. "Association between Epstein-Barr virus reactivation and severe malaria in pregnant women living in a malaria-endemic region of Cameroon." PLOS Global Public Health 4, no. 8 (2024): e0003556. http://dx.doi.org/10.1371/journal.pgph.0003556.

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Malaria kills nearly 619,000 people each year. Despite the natural immunity acquired to malaria, pregnant women and children under five die from severe forms of the disease in sub-Saharan Africa. Co-infection with acute Epstein-Barr Virus (EBV) infection has been shown to suppress the anti-malarial humoral responses, but little is known about the impact of EBV reactivation on malaria-associated morbidity. This study investigated the association between EBV reactivation and malaria severity in pregnant women living in a malaria-endemic region in Cameroon. A cross-sectional study was conducted o

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Shetty, Archana, Teerthanath Srinivas, and Hariprasad Srinivas. "Platelet count and Superoxide Dismutase as a marker for severity of Plasmodium infection." International Journal of Research in Medical Sciences 5, no. 11 (2017): 4864. http://dx.doi.org/10.18203/2320-6012.ijrms20174934.

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Background: Malaria continues to be an important public health problem in developing and underdeveloped countries with high morbidity and mortality. It continues to be one of the major public health problems in India. Plasmodium vivax is the major parasite type causing malaria and Plasmodium falciparum is the major cause of serious and complicated disease. Haematological abnormality which is most commonly seen in malaria is thrombocytopenia followed by anaemia. Identification of predictors of disease severity is critical to improve patient care. This study was undertaken to evaluate the severi

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Kifude, Carolyne, Deborah Stiffler, David Rockabrand, et al. "Asymptomatic falciparum and Non-falciparum Malarial Parasitemia in Adult Volunteers with and without HIV-1 Coinfection in a Cohort Study in Western Kenya." American Journal of Tropical Medicine and Hygiene 105, no. 1 (2021): 159–66. http://dx.doi.org/10.4269/ajtmh.21-0012.

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Abstract.Asymptomatic malarial parasitemia represents the largest reservoir of infection and transmission, and the impact of coinfection with HIV-1 on this reservoir remains incompletely described. Accordingly, we sought to determine the prevalence of asymptomatic malarial parasitemia in Kombewa, Western Kenya, a region that is endemic for both malaria and HIV-1. A total of 1,762 dried blood spots were collected from asymptomatic adults in a cross-sectional study. The presence of parasitemia was first determined by a sensitive Plasmodium genus–specific 18S assay, followed by less sensitive spe

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Mwesigwa, Moses, Jessica L. Webster, Sam Lubwama Nsobya, et al. "Prevalence of Malaria Parasite Infections among U.S.-Bound Congolese Refugees with and without Splenomegaly." American Journal of Tropical Medicine and Hygiene 104, no. 3 (2021): 996–99. http://dx.doi.org/10.4269/ajtmh.20-0924.

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ABSTRACTAll U.S.-bound refugees from sub-Saharan Africa receive presumptive antimalarial treatment before departing for the United States. Among U.S.-bound Congolese refugees, breakthrough malaria cases and persistent splenomegaly have been reported. In response, an enhanced malaria diagnostic program was instituted. Here, we report the prevalence of plasmodial infection among 803 U.S.-bound Congolese refugees who received enhanced diagnostics. Infections by either rapid diagnostic test (RDT) or PCR were detected in 187 (23%) refugees, with 78 (10%) by RDT only, 35 (4%) by PCR only, and 74 (9%

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9

OHNISHI, Kenji, Yasuyuki KATO, and Shigeyuki KANO. "Mixed Infection of Malariae Malaria and Falciparum Malaria." Journal of the Japanese Association for Infectious Diseases 75, no. 3 (2001): 219–21. http://dx.doi.org/10.11150/kansenshogakuzasshi1970.75.219.

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10

Abhigyan, Kumar, and Shankar Vaibhav. "To Analyse the Clinical Characteristics of Falciparum, Vivax, and Mixed Infections of Malaria: A Retrospective Study." International Journal of Current Pharmaceutical Review and Research 16, no. 03 (2024): 544–50. https://doi.org/10.5281/zenodo.12792691.

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AbstractAim: To analyse the clinical characteristics of falciparum, vivax, and mixed infections of malaria in a tertiary carehospital in Bihar, India.Material and Methods: A retrospective study was conducted in the Department of general medicine, Netajisubhas medical college and hospital, Bihta, Patna, Bihar, India for one year .All adult patients (>15 years of age)admitted with the diagnosis of P. vivax malaria, P. falciparum, and mixed malarial infection. The diagnosis ofmalaria was made based on the detection of malaria parasites by conventional thick and thin peripheral bloodfilms, stai

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Rubio, J. M., A. Benito, P. J. Berzosa, et al. "Usefulness of Seminested Multiplex PCR in Surveillance of Imported Malaria in Spain." Journal of Clinical Microbiology 37, no. 10 (1999): 3260–64. http://dx.doi.org/10.1128/jcm.37.10.3260-3264.1999.

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The use of a new PCR-based method for the diagnosis of malaria in the Spanish Malaria Reference Laboratory has promoted an increase in confirmed cases of malaria. From August 1997 to July 1998, a total of 192 whole-blood samples and 71 serum samples from 168 patients were received from the hospitals of the Spanish National Health System. Most of the patients came from west-central African countries (85%). This molecular method showed more sensitivity and specificity than microscopy, detecting 12.4% more positive samples than microscopy and 13% of mixed infections undetectable by Giemsa stain.

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Singh, Kuldeep, Praveen Kumar Bharti, Naorem Chaoba Devi, Naseem Ahmed, and Amit Sharma. "Plasmodium malariae Detected by Microscopy in the International Bordering Area of Mizoram, a Northeastern State of India." Diagnostics 12, no. 8 (2022): 2015. http://dx.doi.org/10.3390/diagnostics12082015.

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Northeastern states of India share international borders with Myanmar, China, Bangladesh, and Bhutan, contributing 7.45% of the overall malaria cases in the country. Mizoram accounts for the highest malaria burden in the northeastern states, with perennial transmission in the hilly and deep-forested areas. Plasmodium falciparum (93%) is the most prevalent human Plasmodium species, followed by P. vivax; however, information on P. ovale and P. malariae is negligible. Rapid diagnostic tests (RDTs) are the most preferred malaria diagnostic tool followed by microscopy in this high malaria-endemic r

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Iqbal, Jamshaid, Mohammad Al-Awadhi, and Suhail Ahmad. "Decreasing trend of imported malaria cases but increasing influx of mixed P. falciparum and P. vivax infections in malaria-free Kuwait." PLOS ONE 15, no. 12 (2020): e0243617. http://dx.doi.org/10.1371/journal.pone.0243617.

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Malaria still continues to be the most important parasitic disease worldwide, affecting 228 million people and causing 405,000 deaths each year. In this retrospective study during 2013 to 2018, we documented the incidence of imported malaria infection and evaluated the impact of malaria preventive measures in Kuwait, a non-endemic country. The epidemiologic and demographic data of all malaria cases was collected from the Infectious Diseases Hospital, Kuwait where all suspected cases of malaria are referred for confirmation and therapeutic intervention. The diagnosis of malaria infection was do

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Babokh, Fatima, Soumia Nachat, Ibtissam Ait Boucetta, Youssra El Amrani, Fatimzahra Rahali, and Awatif El Hakkouni. "MIXED MALARIA INFECTION: ABOUT AN IMPORTED CASE AND REVIEW OF THE LITERATURE." International Journal of Advanced Research 10, no. 04 (2022): 481–85. http://dx.doi.org/10.21474/ijar01/14571.

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Mixed malaria infections with Plasmodium are rare and can lead to more serious complications than a single infection. They are particularly common in travelers to malaria-endemic areas. Proper diagnosis and treatment of cases help to control this infection.We report the case of a rare and severe malaria infection, associating two plasmodial species: Plasmodium falciparum and P.vivax, with high parasitemia and fatal complication.

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Mayxay, Mayfong, Sasithon Pukrittayakamee, Paul N. Newton, and Nicholas J. White. "Mixed-species malaria infections in humans." Trends in Parasitology 20, no. 5 (2004): 233–40. http://dx.doi.org/10.1016/j.pt.2004.03.006.

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McKenzie, F. E., and D. L. Smith. "Mixed‐Species Malaria Infections in Travelers." Journal of Travel Medicine 13, no. 2 (2006): 123.1–123. http://dx.doi.org/10.1111/j.1708-8305.2006.00025.x.

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17

Bhowmick, Ipsita Pal, Tulika Nirmolia, Apoorva Pandey, et al. "Dry Post Wintertime Mass Surveillance Unearths a Huge Burden of P. vivax, and Mixed Infection with P. vivax P. falciparum, a Threat to Malaria Elimination, in Dhalai, Tripura, India." Pathogens 10, no. 10 (2021): 1259. http://dx.doi.org/10.3390/pathogens10101259.

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With India aiming to achieve malaria elimination by 2030, several strategies have been put in place. With that aim, mass surveillance is now being conducted in some malaria-endemic pockets. As dry season mass surveillance has been shown to have its importance in targeting the reservoir, a study was undertaken to assess the parasite load by a sensitive molecular method during one of the mass surveys conducted in the dry winter period. It was executed in two malaria-endemic villages of Dhalai District, Tripura, in northeast India, also reported as P. falciparum predominated area. The present stu

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Rodulfo, Hectorina, Marcos de Donato, Isaurea Quijada, and Ada Peña. "High prevalence of malaria infection in Amazonas state, Venezuela." Revista do Instituto de Medicina Tropical de São Paulo 49, no. 2 (2007): 79–85. http://dx.doi.org/10.1590/s0036-46652007000200003.

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This study was carried out to determine the incidence of malaria in an endemic region of Amazonas State, Venezuela. For this, 200 random samples were collected from symptomatic and asymptomatic individuals from San Fernando de Atabapo and Santa Barbara. Epidemiological factors were related to malaria infection, which was diagnosed by microscopy observation and amplification of the 18S rDNA sequence by PCR. Malaria prevalence in these populations was 28.5%, whilst P. vivax and P. falciparum prevalences were 12 and 17%, respectively. No infection by P. malariae was found. A mixed infection was f

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Nkemngo, Francis N., Lymen W. G. Raissa, Derrick N. Nebangwa, et al. "Epidemiology of malaria, schistosomiasis, and geohelminthiasis amongst children 3–15 years of age during the dry season in Northern Cameroon." PLOS ONE 18, no. 7 (2023): e0288560. http://dx.doi.org/10.1371/journal.pone.0288560.

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Background The double burden of malaria and helminthiasis in children poses an obvious public health challenge, particularly in terms of anemia morbidity. While both diseases frequently geographically overlap, most studies focus on mono-infection and general prevalence surveys without molecular analysis. The current study investigated the epidemiological determinants of malaria, schistosomiasis, and geohelminthiasis transmission among children in the North Region of Cameroon. Methodology School and pre-school children aged 3–15 year-of-age were enrolled from three communities in March 2021 usi

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Jacobs, Nathan Thomas, Jessie Barra, Rustom Antia, and Tracey J. Lamb. "Inflammatory monocytes mediate competition between genetically diverse malaria parasites during mixed-strain Plasmodium infections." Journal of Immunology 196, no. 1_Supplement (2016): 134.6. http://dx.doi.org/10.4049/jimmunol.196.supp.134.6.

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Abstract In areas of intense malaria transmission, many individuals receive multiple infectious bites per night, leading to overlapping infections with multiple strains of Plasmodium. As the transmission likelihood of a given strain is influenced by blood-stage parasite densities, parasites that can multiply faster and avoid immune clearance mechanisms are more competitively fit and are likely to be favored by evolution. Competitive ability has previously been linked to the virulence of infection, but mechanistic details are unclear. Here, we demonstrate a role for innate phagocytic cells, spe

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Gayoso-Cantero, Diego, María Dolores Corbacho-Loarte, Clara Crespillo-Andújar, et al. "Changes in Lipid Profile Secondary to Asymptomatic Malaria in Migrants from Sub-Saharan Africa: A Retrospective Analysis of a 2010–2022 Cohort." Tropical Medicine and Infectious Disease 10, no. 5 (2025): 134. https://doi.org/10.3390/tropicalmed10050134.

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Altered lipid profiles have been observed in acute malaria, though mechanisms remain unclear. The impact of asymptomatic submicroscopic malaria infection (AMI) on lipids is unexploredAn observational, comparative, retrospective study was conducted of 1278 asymptomatic Sub-Saharan African migrants (ASSAMs) screened for malaria and lipid profiles during health exams (2010–2022). A systematic screening protocol for infectious disease was performed, including screening for Plasmodium spp. infection by polymerase chain reaction (PCR).Among 800 ASSAMs screened for malaria, 104 (13%) were PCR-positiv

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Munagala, Venkata Krishna, Ramisetty M. UmaMahesh, Kandati Jithendra, Muni Lakshmi Ponugoti, and Mohan Rao Nandam. "Clinico-epidemiological features of malaria among children attending a tertiary care hospital: a two year study." International Journal of Contemporary Pediatrics 4, no. 5 (2017): 1781. http://dx.doi.org/10.18203/2349-3291.ijcp20173785.

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Background: Malaria caused by Plasmodium species and transmitted by Female anopheles mosquito, still remains as a major public health concern around the world. India is one of the major contributors of malaria cases in South East Asia. Malaria accounts for 205,000 deaths with 55,000 deaths occurring in early childhood. In endemic areas, children under 5 years are particularly susceptible to infection, illness and death. The present study was aimed to study the clinical, epidemiological profile of malaria cases among children (<12 years) attending a tertiary care hospital. We also assessed t

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Lundqvist, Jenny, Christer Larsson, Maria Nelson, Marie Andersson, Sven Bergström, and Cathrine Persson. "Concomitant Infection Decreases the Malaria Burden but Escalates Relapsing Fever Borreliosis." Infection and Immunity 78, no. 5 (2010): 1924–30. http://dx.doi.org/10.1128/iai.01082-09.

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ABSTRACT About 500 million cases of malaria occur annually. However, a substantial number of patients who actually have relapsing fever (RF) Borrelia infection can be misdiagnosed with malaria due to similar manifestations and geographic distributions of the two diseases. More alarmingly, a high prevalence of concomitant infections with malaria and RF Borrelia has been reported. Therefore, we used a mouse model to study the effects of such mixed infection. We observed a 21-fold increase in spirochete titers, whereas the numbers of parasitized erythrocytes were reduced 15-fold. This may be expl

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Zohaib Abbasi, Abdul Ghani Rahimoon, Kashif Shaikh, Muhammad Awais Qadri, Ghulam Rasool Rahimoon, and Aakash Rai. "Prevalence of Malaria in Febrile Patients Presenting with Thrombocytopenia at LUMHS, Jamshoro." Annals of PIMS-Shaheed Zulfiqar Ali Bhutto Medical University 21, no. 1 (2025): 286–90. https://doi.org/10.48036/apims.v21i1.1035.

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Objective: To determine the frequency of malaria in febrile patients presenting with thrombocytopenia at LUMHS, Jamshoro. Methodology: A cross sectional study was conducted at Department of Medicine, LUMHS, Jamshoro, Hyderabad, during six months from 01-02-2023 till 31-7-2023. Febrile patients with thrombocytopenia, either gender aged 20-80 years were included. Blood sample was obtained from each cases and analyzed for complete blood count (CBC) and malaria diagnosis using Giemsa-stained thin and thick blood smears. Patients were assessed and labeled as malaria-positive based on the presence o

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Telfils, Rodeline, Akpéyédjé Yannelle Dossou, Armel Djènontin, et al. "Dynamics of submicroscopic and microscopic asymptomatic malaria infection and associated factors: A longitudinal study in South Benin." PLOS ONE 19, no. 12 (2024): e0311217. https://doi.org/10.1371/journal.pone.0311217.

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Introduction Asymptomatic malaria infection is now recognized as a potential threat to malaria control. However, its prevalence and its dynamics are poorly documented especially in a perennial context of high seasonal transmission. A longitudinal study was conducted in southern Benin to investigate the dynamics of asymptomatic malaria infection and to identify factors influencing it. Methods A cohort of 377 participants was recruited, stratified into three age groups (under 5 years, between 5 and 15 years, over 15 years). After inclusion, two visits were made one-month apart between August and

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Makmur, Tri, Fazidah Siregar, Sahat Siregar, Ichwan Lubis, Ramadhan Bestari, and Umar Zein. "Open Clinical Trial of Sambiloto (Andrographis paniculata) Ethanolic Extract Capsules in Treatment of Malaria Patients in Batubara District, Indonesia." Medical Archives 76, no. 6 (2022): 419. http://dx.doi.org/10.5455/medarh.2022.76.419-425.

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Background: Malaria infection is still a public health problem in Indonesia. One of the problems in combating malaria in Indonesia is the limited kind of antimalarial drugs provided by the government. Sambiloto (Andrographis paniculata) extract has been shown to have antimalarial activity in human clinical trials. Objective: To assess the ability of a single A. paniculata eethanolic extract capsule to treat malaria in humans caused by Plasmodium falciparum or P. vivax alone or mixed infections of both. Methods: An open clinical trial was conducted in Batubara District, Sumatra Utara Province,

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Cavasini, Marisa Torres Vidal, Weber Luidi Ribeiro, Fumihiko Kawamoto, and Marcelo Urbano Ferreira. "How prevalent is Plasmodium malariae in Rondônia, Western Brazilian Amazon?" Revista da Sociedade Brasileira de Medicina Tropical 33, no. 5 (2000): 489–92. http://dx.doi.org/10.1590/s0037-86822000000500011.

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We have compared results of Plasmodium species identification obtained with conventional on-site microscopy of Giemsa-stained thick smears (GTS) and a semi-nested polymerase chain reaction (PCR) in 96 malaria patients from Rondônia, Western Brazilian Amazon. Mixed-species infections were detected by PCR in 30% patients, but no such case had been found on GTS. Moreover, P. malariae infections were detected in 9 of 96 patients (10%) by PCR, but were not identified by local microscopists. The potential impact of species misidentification on malaria treatment and control is discussed.

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Punnath, Kishore, Kiran K. Dayanand, Valleesha N. Chandrashekar, et al. "Association between Inflammatory Cytokine Levels and Thrombocytopenia during Plasmodium falciparum and P. vivax Infections in South-Western Coastal Region of India." Malaria Research and Treatment 2019 (April 11, 2019): 1–10. http://dx.doi.org/10.1155/2019/4296523.

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Background. Thrombocytopenia is a most commonly observed complication during malaria infections. Inflammatory cytokines such as IL-1, IL-6, and IL-10 have been documented in malaria induced thrombocytopaenia. This study was aimed to understand the possible relationship between inflammatory cytokines across varying degrees of thrombocytopenia during P. vivax, P. falciparum, and mixed infections. Methods. A hospital-based cross sectional study was conducted at District Wenlock Hospital in Mangaluru, a city situated along the south-western coastal region of Arabian Sea in India. In this study, bl

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ROPER, C., W. RICHARDSON, I. M. ELHASSAN, et al. "Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village." Parasitology 116, no. 6 (1998): 501–10. http://dx.doi.org/10.1017/s0031182098002650.

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Residents of Daraweesh village in Sudan were monitored for Plasmodium falciparum infection and malaria morbidity in 3 malaria seasons from 1993 to 1996. Malaria parasites were detected microscopically and by polymerase chain reaction (PCR) in a series of cross-sectional surveys. PCR revealed submicroscopical infections during the dry season, particularly among individuals who had recovered from a malaria episode following successful drug treatment. Clinical and subclinical infections were contrasted by assaying for allelic polymorphism at 2 gene loci, MSP-1 and GLURP and 2 hypotheses examined

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DE ROODE, J. C., A. F. READ, B. H. K. CHAN, and M. J. MACKINNON. "Rodent malaria parasites suffer from the presence of conspecific clones in three-clonePlasmodium chabaudiinfections." Parasitology 127, no. 5 (2003): 411–18. http://dx.doi.org/10.1017/s0031182003004001.

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We studied infection dynamics ofPlasmodium chabaudiin mice infected with 3 genetically distinct clones – 1 less virulent than the other 2 – either on their own or in mixtures. During the acute phase of infection, total numbers of asexual parasites in mixed-clone infections were equal to those produced by the 3 clones alone, suggesting strong in-host competition among clones. During the chronic phase of the infection, mixed-clone infections produced more asexual parasites than single-clone infections, suggesting lower levels of competition than during the acute phase, and indicating that a gene

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Basnyat, Buddha. "Mixed Malaria Infection." Journal of Travel Medicine 6, no. 1 (1999): 50–51. http://dx.doi.org/10.1111/j.1708-8305.1999.tb00868.x.

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Mohammadzadeh, Tahereh, Gholamreza Hatam, Mohsen Kalantari, et al. "Molecular and Microscopic-Based Characterization ofPlasmodiumspp. in Fars and Hormozgan Provinces, South of Iran." Journal of Tropical Medicine 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/935469.

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Despite malaria control programs in recent years, malaria transmission has not been eliminated in Iran. Molecular techniques including PCR, which has proved more sensitive and specific than microscopic examination methods, help to detect infection in low levels of parasitemia and mixed infections. Main our objectives were setting up nested PCR for detection of malaria and evaluating PCR based on plasmodia DNA from blood smears in Fars province, the comparison of this method with traditional microscopy and also evaluate the data in comparison with its neighboring province, Hormozgan. A total of

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Atah, Formbui Paul, Njunda Anna Longdoh, Benjamin Pokam Thumamo, and Jane Francis Akoachere. "Malaria, HIV, and Intestinal Coccidian Parasites Mixed-Infections in Adult Patients in the Fundong Health District, Northwest Region, Cameroon." International Journal of TROPICAL DISEASE & Health 44, no. 19 (2023): 16–29. http://dx.doi.org/10.9734/ijtdh/2023/v44i191480.

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Background: Malaria and intestinal coccidian parasites are both protozoan and their interaction in co-infected patients is still not clear. Patients infected with both malaria and coccidian parasites experience diarrhoea, gastro-intestinal and health problems that maybe life threating. We studied opportunistic intestinal coccidian parasites (OIPs) and the human immunodeficiency virus (HIV) in adult patients with malaria in Fundong Health District, Northwest of Cameroon. The objectives was to determine prevalence, and distribution of the diseases in adult population.  Methods: A prospecti

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Amiah, Mireille A., David T. Okou, Paterne A. Gnagne, et al. "Mixed Plasmodium Species Infections and Malaria Susceptibility among Fulani, Lobi and Birifor Ethnic Groups in Bouna, Côte d’Ivoire." International Journal of TROPICAL DISEASE & Health 46, no. 5 (2025): 32–44. https://doi.org/10.9734/ijtdh/2025/v46i51655.

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Background: Malaria remains a major health problem in sub-Saharan Africa. One of the main challenges that researchers are facing in eliminating the parasite is chemoresistance to antimalarial drugs. Resistance to artemisinin, the main molecule of drug combinations used in malaria treatment, has been observed in Asia, as well as in Africa. Aims: The aim is to study malaria susceptibility among a rural population of Bouna, in Côte d’Ivoire, that includes the Fulani and understand the influence of mixed infections on this susceptibility. Methodology: This is a Cross-sectional study. The study was

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Mubaraki, Murad A., Mubbashir Hussain, Fozia Fozia, et al. "Incidence of Helminthic and Viral Coinfections in Malaria Patients in the Tertiary Care Hospital Setup." Journal of Tropical Medicine 2024 (March 28, 2024): 1–10. http://dx.doi.org/10.1155/2024/8529788.

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Introduction. This study determines the incidence of common viral and helminth coinfections with malaria in the tertiary care hospital set up in southern Khyber Pakhtunkhwa, Pakistan. Materials and Methods. The multidimensional research included malaria patients admitted to different hospitals of district Kohat during January and December 2021. Stool samples and blood were assembled from the patients. Giemsa-stained microscopy-positive samples were processed by the immunochromatography technique (ICT) to identify Plasmodium species. Common viral infections such as viral hepatitis (A, B, and C)

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Black, Julie, Marcel Hommel, Georges Snounou, and Margaret Pinder. "Mixed Infections with Plasmodium falciparum and P malariae and fever In malaria." Lancet 343, no. 8905 (1994): 1095. http://dx.doi.org/10.1016/s0140-6736(94)90203-8.

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Dinko, Bismarck, Reuben Ayivor-Djanie, James Abugri, Eric Agboli, and al. et. "Comparison of malaria diagnostic methods in four hospitals in the Volta region of Ghana." MalariaWorld Journal 7, no. 5 (2016): 1–7. https://doi.org/10.5281/zenodo.10797112.

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<strong>Background.</strong> Rapid diagnostic tests (RDTs) and microscopy ar e routinely used for the diagnosis of malaria in Ghana. DNA-based polymerase chain reaction (PCR) is not yet used routinely. We compared diagnostic methods and tested the sensitivities of different malaria diagnostic methods against PCR. <strong>Materials and methods.</strong> Study participants from four hospitals with a suspicion of malaria donated finger -prick blood for RDT and blood film examination. In addition, a blood spot was collected for PCR analysis, prior to treatment. Retrospective species-specific PCR w

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MOLLOY, S. F., C. J. TANNER, P. KIRWAN, et al. "Sporadic Cryptosporidium infection in Nigerian children: risk factors with species identification." Epidemiology and Infection 139, no. 6 (2010): 946–54. http://dx.doi.org/10.1017/s0950268810001998.

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SUMMARYA cross-sectional study was conducted to investigate risk factors for sporadic Cryptosporidium infection in a paediatric population in Nigeria. Of 692 children, 134 (19·4%) were infected with Cryptosporidium oocysts. Cryptosporidium spp. were identified in 49 positive samples using PCR–restriction fragment length polymorphism and direct sequencing of the glycoprotein60 (GP60) gene. Generalized linear mixed-effects models were used to identify risk factors for all Cryptosporidium infections, as well as for C. hominis and C. parvum both together and separately. Risk factors identified for

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Jagannadham, Rajendraprasad, Sridhar Reddy K., Ashalata Tammineni, B.V.S. Kartheek, and V.Lalitha. "To Study the Significance of Hematological Parameters in Differentiating Malaria and Non-Malarial Acute Febrile Illness in a Tertiary Care Hospital in Visakhapatnam." International Journal of Pharmaceutical and Clinical Research 16, no. 1 (2024): 551–55. https://doi.org/10.5281/zenodo.11099110.

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<strong>Background:</strong> Malaria is a common infectious disease and rarely can be life threatening if not treated properly. It is one of the major health problems in most populated areas of world [1] and an important cause of acute febrile illness in India. According to WHO’s latest world Malaria report, there were an estimated 249 million malaria cases in 2022 in 85 malaria endemic countries, increasing from 224 million in 2021. <strong>Method:</strong> The study was an observational study carried out in King George Hospital (KGH) Visakhapatnam. The study population w

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Bushman, Mary, Lindsay Morton, Nancy Duah, et al. "Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum." Proceedings of the Royal Society B: Biological Sciences 283, no. 1826 (2016): 20153038. http://dx.doi.org/10.1098/rspb.2015.3038.

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Infections with the malaria parasite Plasmodium falciparum typically comprise multiple strains, especially in high-transmission areas where infectious mosquito bites occur frequently. However, little is known about the dynamics of mixed-strain infections, particularly whether strains sharing a host compete or grow independently. Competition between drug-sensitive and drug-resistant strains, if it occurs, could be a crucial determinant of the spread of resistance. We analysed 1341 P. falciparum infections in children from Angola, Ghana and Tanzania and found compelling evidence for competition

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Markus, Miles B. "Source of Clinical Malaria in Mixed‐Species Infections." Journal of Travel Medicine 19, no. 4 (2012): 275. http://dx.doi.org/10.1111/j.1708-8305.2012.00622.x.

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Juthani, Ronit, Tavish Gupta, and Debdatta Basu. "Scatterplot Variations Seen in Malaria Using Automated Hematological Analyzers: A Series of Ten Cases." International Journal of Medical Students 9, no. 1 (2021): 21–24. http://dx.doi.org/10.5195/ijms.2021.866.

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Background: Malaria is a major health problem in India. Complete blood count and peripheral blood smear (PBS) is important for its diagnosis. Inter observer variation makes PBS fallible. Rapid diagnostic tests cannot detect low parasitemia and mixed infections. Scatterplot from automated analyzers have shown variations previously which might be exploited. Methods: Scatterplot patterns of ten samples of confirmed malaria and 100 control samples were derived and other infections ruled out by culture and serology as a part of descriptive study between July and August 2018. Each malarial sca

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TAYLOR, L. H., D. WALLIKER, and A. F. READ. "Mixed-genotype infections of the rodent malaria Plasmodium chabaudi are more infectious to mosquitoes than single-genotype infections." Parasitology 115, no. 2 (1997): 121–32. http://dx.doi.org/10.1017/s0031182097001145.

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Interactions between parasite genotypes sharing a host are poorly understood, but have important consequences for the epidemiology and evolution of the parasite. In mixed-genotype malaria infections, patterns of asexual replication and transmission favoured by natural selection may be different from those in single-genotype infections. The infectivity to mosquitoes of mixed-genotype and single-genotype infections were compared using 2 clones of Plasmodium chabaudi inoculated into mice either together or alone. Mice given mixed-clone infections received the sum of the inocula given to the singl

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Rondón Carvajal, Julián. "Mixed malaria: the paradox of visual diagnosis in the tropics." Annals of Critical Care and Medicine 6, no. 1 (2024): 1–4. http://dx.doi.org/10.52338/accm.2024.3998.

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Malaria is the parasitic disease with the greatest impact on humans. It is an infectious disease caused by protozoa of the genus Plasmodium spp. and transmitted to humans by the bite of the mosquito Anopheles spp. Its incidence has increased in the tropical regions of Africa and Southeast Asia, areas already defined by the World Health Organization (WHO) as malarial zones [1]. In these places, malaria generally disappears at altitudes above 2.000 meters above sea level. The most frequently circulating parasites are P. vivax and P. falciparum; P. malarie is also widely distributed, but less fre

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Chandra, Shekhar Das, Kumar Ranjan Rajeshwer, and Agrawal Chirag. "A Hospital Based Assessment of Clinical Profile of Falciparum, Vivax and Mixed Infections of Malaria." International Journal of Pharmaceutical and Clinical Research 13, no. 6 (2021): 804–8. https://doi.org/10.5281/zenodo.14228219.

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<strong>Aim:</strong> The aim of our study was to find out the spectrum of clinical manifestations, infecting species, age distribution and mortality in admitted patients of malaria in our hospital and to compare the clinical profile with severity of P.vivax and P. falciparum malaria in pediatrics age group in a tertiary care hospital. <strong>Methods: </strong>Malaria confirmed by Peripheral thick and thin smear or Antigen Assay underwent detailed clinical history and physical examination. Statistical analysis was done using chi square test for comparing proportions. P value &l

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Ranjane, Sangeeta, Shubhada Girish Vengurlekar, Meeta Piyush Shah, and Vandana Parag Kambli. "Exploring Biochemical and Hematological Variations in Malaria Cases: A Retrospective Analysis at a Health Center at Mumbai City India." Asian Journal of Biochemistry, Genetics and Molecular Biology 16, no. 3 (2024): 1–7. http://dx.doi.org/10.9734/ajbgmb/2024/v16i3361.

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Introduction: In Mumbai, an overpopulated metropolis with tropical conditions, malaria poses a persistent challenge, particularly in damp slum areas. Despite reported declines in death and incidence rates, the city faces a significant burden. Our project focuses on an unusual aspect: a heightened incidence among males, especially during sporadic monsoon outbreaks and in areas undergoing extensive redevelopment. Through an epidemiological survey of infected populations in municipal clinics, supported by microscopic, hematological, and microbiological evidence, we aim to provide insights into th

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Masaku, Janet, Francis Mutuku, Jimmy H. Kihara, et al. "Helminthiasis and malaria co-infection among women of reproductive age in a rural setting of Kilifi County, coastal Kenya: A mixed method study." PLOS Global Public Health 4, no. 6 (2024): e0003310. http://dx.doi.org/10.1371/journal.pgph.0003310.

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Soil transmitted helminthiasis (STH), Schistosoma haematobium and malaria co-infection lead to increased susceptibility to other infections and poor pregnancy outcomes among women of reproductive age (WRA). This study sought to establish risk factors, burden of co-infection with STH, S. haematobium and Plasmodium sp. among WRA in Kilifi County, Kenya.A mixed method cross-sectional study was conducted on 474 WRA in 2021. Simple random sampling was used to select WRA from four villages in two purposively sampled sub-counties. Study participants were interviewed, and stool samples collected and a

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Antia, Rustom, Andrew Yates, and Jacobus C. de Roode. "The dynamics of acute malaria infections. I. Effect of the parasite's red blood cell preference." Proceedings of the Royal Society B: Biological Sciences 275, no. 1641 (2008): 1449–58. http://dx.doi.org/10.1098/rspb.2008.0198.

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What determines the dynamics of parasite and anaemia during acute primary malaria infections? Why do some strains of malaria reach higher densities and cause greater anaemia than others? The conventional view is that the fastest replicating parasites reach the highest densities and cause the greatest loss of red blood cells (RBCs). Other current hypotheses suggest that the maximum parasite density is achieved by strains that either elicit the weakest immune responses or infect the youngest RBCs (reticulocytes). Yet another hypothesis is a simple resource limitation model where the peak parasit

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Qureshi, Ihtesham, Mohtashim A. Qureshi, Rohit K. Gudepu, and Nimmathota Arlappa. "Prevalence of malaria infection among under five year tribal children residing in malaria endemic forest villages." F1000Research 3 (November 20, 2014): 286. http://dx.doi.org/10.12688/f1000research.5632.1.

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Malaria is a life-threatening protozoal infection and India has the highest malaria burden in South East Asia. The objective of this communication is to assess the prevalence of malaria infection amongst forest dwelling tribal children under the age of five residing in malaria endemic regions of the Andhra Pradesh and Chhattisgarh states of India. A total of 5,801 children attended seven outpatient mobile clinics in 2012. Of them, 2,123 children had a history of fever and were screened for malaria with a Rapid Diagnostic Test (RDT). About 37% of children had a history of fever. Of them, 34% ch

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Fotedar, P., S. S. Rairikar, Ashok J. Vankudre, and S. V. Mahajan. "Descriptive Study of the Hematological Parameters with Special Reference to the Total Leucocyte and Platelet Count in Cases of Malaria in all age Groups." MVP Journal of Medical Sciences 1, no. 1 (2014): 36. http://dx.doi.org/10.18311/mvpjms/2014/v1/i1/833.

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<strong>Introduction &amp; Aim:</strong> To study variation of haematological parameters in different species of malaria with special reference to the total leucocyte and platelet count. <strong>Methods:</strong> This study was conducted in a Tertiary Health Care Centre, from June 2010 to June 2012. All positive cases of malaria proved on peripheral blood smear in both IPD and OPD patients were included in our study and all cases negative for malaria were excluded. <strong>Results:</strong> During this study, 119 positive cases of malaria were found in a

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