Relevant bibliographies by topics / MLC601

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  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'MLC601'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "MLC601"

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Tan, Chai-Hoon Nowel, David Choy, and Narayanaswamy Venketasubramanian. "NeuroAid II (MLC901) in Haemorrhagic Stroke." Case Reports in Neurology 12, Suppl. 1 (2020): 212–17. http://dx.doi.org/10.1159/000508588.

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Stroke is a leading cause of death and disability. NeuroAid (MLC601), which originates from Traditional Chinese Medicine, comprises herbal and animal components, and has been shown to improve the functional status of patients after ischaemic stroke. The use of NeuroAid II (MLC901), which comprises only the herbal components of MLC601, in haemorrhagic stroke has not been previously reported. Our patient is a 63-year-old male with a significant stroke risk factor of hypertension. He developed visual field defect, aphasia, unilateral weakness, and hemisensory loss. CT scan showed a left thalamic
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Navarro, Jose C., Mark C. Molina, Alejandro C. Baroque II, and Johnny K. Lokin. "The Use of NeuroAiD (MLC601) in Postischemic Stroke Patients." Rehabilitation Research and Practice 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/506387.

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Aim. We aimed to assess the efficacy of MLC601 on functional recovery in patients given MLC601 after an ischemic stroke.Methods. This is a retrospective cohort study comparing poststroke patients given open-label MLC601 (; 9 female) for three months and matching patients who did not receive MLC601 from our Stroke Data Bank. Outcome assessed was modified Rankin Scale (mRS) at three months and analyzed according to: (1) achieving a score of 0-2, (2) achieving a score of 0-1, and (3) mean change in scores from baseline.Results. At three months, 21 patients on MLC601 became independent as compared
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Al Fauzi, Asra, Krisna Tsaniadi Prihastomo, I. G. M. Aswin R. Ranuh, et al. "Clinical Outcomes of MLC601 (NeuroAiDTM) in Traumatic Brain Injury: A Pilot Study." Brain Sciences 10, no. 2 (2020): 60. http://dx.doi.org/10.3390/brainsci10020060.

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Background: MLC601 is a natural product formulation from Chinese medicine that is extensively studied in ischemic stroke. Traumatic brain injury (TBI) shares pathophysiological mechanisms with ischemic stroke, yet there are few studies on the use of MLC601 in treating TBI. This Indonesian pilot study aimed to investigate clinical outcomes of MLC601 for TBI. Methods: This randomized controlled trial included subjects with nonsurgical moderate TBI allocated into two groups: with and without MLC601 over three months in addition to standard TBI treatment. Clinical outcomes were measured by the Gla
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Pakdaman, Hossein, Ali Amini Harandi, Mehdi Abbasi, et al. "Efficacy and Safety of MLC601 in the Treatment of Mild Cognitive Impairment: A Pilot, Randomized, Double-Blind, Placebo-Controlled Study." Dementia and Geriatric Cognitive Disorders Extra 7, no. 1 (2017): 136–42. http://dx.doi.org/10.1159/000458521.

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Background and Aim: Mild cognitive impairment (MCI) is characterized by declined cognitive function greater than that expected for a person’s age. The clinical significance of this condition is its possible progression to dementia. MLC601 is a natural neuroprotective medication that has shown promising effects in Alzheimer disease. Accordingly, we conducted this randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of MLC601 in MCI patients. Methods: Seventy-two patients with a diagnosis of MCI were recruited. The included participants were randomly assigned to
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Venketasubramanian, Narayanaswamy, Yogesh Pokharkar, Jia Hui Chai, and Christopher Li Hsian Chen. "Ischemic Stroke and Savings in Time to Achieve Functional Recovery: Experience from NeuroAiD." Journal of Cardiovascular Development and Disease 10, no. 3 (2023): 117. http://dx.doi.org/10.3390/jcdd10030117.

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Despite recent progress with revascularisation interventions after acute ischemic stroke, many patients remain disabled after stroke. Using data from a multi-centre, randomised, double-blind, placebo-controlled trial of a neuro-repair treatment (NeuroAiD/MLC601) with a long-term follow-up, we analysed the savings in time to functional recovery, measured by a modified Rankin Scale (mRS) score of 0 or 1, in patients receiving a 3-month oral course of MLC601. Analysis of time to recovery was assessed by a log-rank test and hazard ratios (HRs) adjusted for prognosis factors. A total of 548 patient
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Pakdaman, Hossein, Ali Amini Harandi, Hamidreza Hatamian, et al. "Effectiveness and Safety of MLC601 in the Treatment of Mild to Moderate Alzheimer's Disease: A Multicenter, Randomized Controlled Trial." Dementia and Geriatric Cognitive Disorders Extra 5, no. 1 (2015): 96–106. http://dx.doi.org/10.1159/000375295.

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Background: MLC601 is a possible modulator of amyloid precursor protein processing, and in a clinical trial study MLC601 showed some effectiveness in cognitive function in Alzheimer's disease (AD) patients. We aimed to evaluate the effectiveness and safety of MLC601 in the treatment of mild to moderate AD as compared to 3 approved cholinesterase inhibitors (ChEIs) including donepezil, rivastigmine and galantamine. Methods: In a multicenter, nonblinded, randomized controlled trial, 264 volunteers with AD were randomly divided into 4 groups of 66; groups 1, 2, 3 and 4 received donepezil, rivasti
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Suwanwela, Nijasri C., Christopher L. H. Chen, Chun Fan Lee, et al. "Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies." Cerebrovascular Diseases 46, no. 1-2 (2018): 82–88. http://dx.doi.org/10.1159/000492625.

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Background and Purpose: MLC601 has been shown in preclinical studies to enhance neurorestorative mechanisms after stroke. The aim of this post hoc analysis was to assess whether combining MLC601 and rehabilitation has an effect on improving functional outcomes after stroke. Methods: Data from the CHInese Medicine NeuroAiD Efficacy on Stroke (CHIMES) and CHIMES-Extension (CHIMES-E) studies were analyzed. CHIMES-E was a 24-month follow-up study of subjects included in CHIMES, a multi-centre, double-blind placebo-controlled trial which randomized subjects with acute ischemic stroke, to either MLC
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Venketasubramanian, Narayanaswamy, Rajesh B. Moorakonda, Qingshu Lu, and Christopher L. H. Chen. "Frequency and Clinical Impact of Serious Adverse Events on Post-Stroke Recovery with NeuroAiD (MLC601) versus Placebo: The CHInese Medicine Neuroaid Efficacy on Stroke Recovery Study." Cerebrovascular Diseases 49, no. 2 (2020): 192–99. http://dx.doi.org/10.1159/000506070.

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Background: Most comparative clinical trials are designed to assess the treatment effect for efficacy endpoints, with less emphasis on the analysis of safety outcomes. However, an extensive analysis of safety data could demonstrate beneficial results in terms of effectiveness by reducing serious adverse events (SAEs), and their unfavourable clinical impact on the study population. We aimed to conduct an exploratory analysis of the CHInese Medicine Neuroaid Efficacy on Stroke recovery (CHIMES) study safety database comparing the frequency of SAEs and their clinical impacts among subjects having
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SALEH, ARMAN YURISALDI, Riezky Valentina, Tirta Darmawan Susanto, and Dwi Arwandi Yogi Saputra. "Beyond stroke therapy, neuroaid (a chinese herbal) has an effect on cognition and neurogenesis, a bibliometric study." F1000Research 13 (July 16, 2024): 799. http://dx.doi.org/10.12688/f1000research.152581.1.

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Introduction NeuroAiD, also known as MLC601 or MLC901, is a Chinese herbal combination used worldwide for stroke treatment. It contains herbal components and five hewan components. MLC601 contains herbal components and hewan components, while MLC901 has a similar herbal composition. NeuroAiD is used to support neurologic recovery after stroke and to aid cognitive function in Alzheimer’s disease. Studies show that NeuroAiD has potential in treating Alzheimer’s disease and is beneficial in both local and global stroke models and in the Kortikal culture. However, there is limited bibliometric res
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Harandi, A. A., R. Abolfazli, A. Hatemian, et al. "Safety and Efficacy of MLC601 in Iranian Patients after Stroke: A Double-Blind, Placebo-Controlled Clinical Trial." Stroke Research and Treatment 2011 (2011): 1–5. http://dx.doi.org/10.4061/2011/721613.

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Objective. To investigate the safety and efficacy of MLC601 (NeuroAid) as a traditional Chinese medicine on motor recovery after ischemic stroke.Methods. This study was a double-blind, placebo-controlled clinical trial on 150 patients with a recent (less than 1 month) ischemic stroke. All patients were given either MLC601 (100 patients) or placebo (50 patients), 4 capsules 3 times a day, as an add-on to standard stroke treatment for 3 months.Results. Sex, age, elapsed time from stroke onset, and risk factors in the treatment group were not significantly different from placebo group at baseline
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Dissertations / Theses on the topic "MLC601"

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Quintard, Hervé. "Étude des propriétés neuroprotectrices et neurorégénératives du MLC901, issu de la Médecine Traditionnelle Chinoise face à l'ischémie globale et au traumatisme crânien chez le rongeur." Thesis, Nice, 2014. http://www.theses.fr/2014NICE4112/document.

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L’arrêt cardio circulatoire et le traumatisme crânien sont responsables de lésions cérébrales dont les conséquences médico économiques sont un réel enjeu de santé publique. Malgré des espoirs importants lors des travaux expérimentaux, la majorité des traitements neuroprotecteurs se sont révélés être des échecs lors du passage à la clinique humaine. Riche d’une expérience clinique vieille de plusieurs millénaires, la Médecine Chinoise Traditionnelle a démontré son efficacité en clinique sur des patients victimes d’accidents vasculaires cérébraux. Le MLC 601, et sa formule simplifiée le MLC901,
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Quintard, Hervé. "Étude des propriétés neuroprotectrices et neurorégénératives du MLC901, issu de la Médecine Traditionnelle Chinoise face à l'ischémie globale et au traumatisme crânien chez le rongeur." Electronic Thesis or Diss., Nice, 2014. http://theses.unice.fr/2014NICE4112.

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L’arrêt cardio circulatoire et le traumatisme crânien sont responsables de lésions cérébrales dont les conséquences médico économiques sont un réel enjeu de santé publique. Malgré des espoirs importants lors des travaux expérimentaux, la majorité des traitements neuroprotecteurs se sont révélés être des échecs lors du passage à la clinique humaine. Riche d’une expérience clinique vieille de plusieurs millénaires, la Médecine Chinoise Traditionnelle a démontré son efficacité en clinique sur des patients victimes d’accidents vasculaires cérébraux. Le MLC 601, et sa formule simplifiée le MLC901,
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Al-Shboul, Othman. "Differential regulation of MLC20 phosphorylation in tonic and phasic smooth muscles of the stomach." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/2362.

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Gastrointestinal (GI) smooth muscle possesses distinct regional and functional properties that distinguish it from other types of visceral and vascular smooth muscle. On the basis of electrical properties and contractile phenotype, GI smooth muscles have been classified into phasic (non-sphinteric) and tonic (sphinteric) smooth muscles. The biochemical basis of phasic and tonic phenotypes of smooth muscle is not clear and is the major question of inquiry of the present study. Phosphorylation of Ser19 on the 20 kDa myosin light chain (MLC) is essential for acto-myosin interaction and contractio
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Kreutzfeldt, Simon [Verfasser], Klaus-Peter [Gutachter] Lesch, Esther [Gutachter] Asan, and Angelika [Gutachter] Schmitt. "Studien zur Expression von Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben / Simon Kreutzfeldt. Gutachter: Klaus-Peter Lesch ; Esther Asan ; Angelika Schmitt." Würzburg : Universität Würzburg, 2013. http://d-nb.info/1102822779/34.

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Paes, Hugo Costa. "Caracterização do módulo regulador do fator de transcrição Mlc1 de Cryptococcus neoformans." reponame:Repositório Institucional da UnB, 2016. http://repositorio.unb.br/handle/10482/22543.

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Tese (doutorado)—Universidade de Brasília, Faculdade de Medicina, Programa de Pós-Graduação em Patologia Molecular, 2016.<br>Texto liberado parcialmente pelo autor. Conteúdo restrito: Apêndices.<br>Submitted by Fernanda Percia França (fernandafranca@bce.unb.br) on 2016-07-20T15:30:33Z No. of bitstreams: 1 2016_HugoCostaPaes_Parcial.pdf: 3794325 bytes, checksum: 3d01a16ba44758f90caa9750abbd4e47 (MD5)<br>Approved for entry into archive by Raquel Viana(raquelviana@bce.unb.br) on 2017-02-14T21:27:37Z (GMT) No. of bitstreams: 1 2016_HugoCostaPaes_Parcial.pdf: 3794325 bytes, checksum: 3d01a16ba4475
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Duarri, Piqué Anna. "Avenços en la fisiopatologia de la Leucoencefalopatia Megalencefàlica amb Quists subcorticals." Doctoral thesis, Universitat Autònoma de Barcelona, 2010. http://hdl.handle.net/10803/3630.

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La Leucoencefalopatia Megalencefàlica amb quists subcorticals (MLC) és un tipus de leucodistròfia espongiforme d'herència autosòmica recessiva. Està considerada una malaltia rara que es caracteritza per macrocefàlia els primers anys de vida, deteriorament de les funcions motores, atàxia i espasticitat, lleuger retràs mental i en alguns casos atacs epilèptics. El diagnòstic es fa per ressonància magnètica d'imatge ja que els pacients presenten la substància blanca anormalment difusa i quists subcorticals a la regió anterio-temporal i fronto-parietal. Es va descriure el primer gen causant de la
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Siekiera, Markus. "Systematische Mutationsanalyse der Kandidatengene MLC1/KIAA0027 und CERK1/KIAA1646 auf Chromosom 22q13.33 bei periodischer Katatonie." Doctoral thesis, kostenfrei, 2009. http://nbn-resolving.de/urn/resolver.pl?urn=nbn:de:bvb:20-opus-38151.

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Kranz, Thorsten Manfred [Verfasser], and Jobst [Akademischer Betreuer] Meyer. "Potential candidate genes for neuropsychiatric disorders: MLC1, C15orf53 and OXTR / Thorsten Manfred Kranz ; Betreuer: Jobst Meyer." Trier : Universität Trier, 2013. http://d-nb.info/1197698981/34.

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Henseler, Darja [Verfasser], and Jobst [Akademischer Betreuer] Meyer. "Untersuchung potentieller Kandidatengene für Periodische Katatonie und Schizophrenie:Strukturelle und funktionelle Promotoranalyse von Mlc1, Mutationsanalyse von BUB1B und Assoziationsstudie zu CHRNA7, DAOA und BRD1 / Darja Henseler ; Betreuer: Jobst Meyer." Trier : Universität Trier, 2010. http://d-nb.info/1197696954/34.

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Cable, Morgan Leigh. "Life in Extreme Environments: Lanthanide-Based Detection of Bacterial Spores and Other Sensor Design Pursuits." Thesis, 2010. https://thesis.library.caltech.edu/5791/19/mlc11.CIF.

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Bacterial spores, or endospores, are produced by certain genera of bacteria under stress and are considered to be one of the most resilient forms of life on Earth. Detection of endospores is vital in areas ranging from bioburden reduction to homeland security. Rapid bacterial spore detection is achieved by targeting dipicolinic acid (DPA), a chemical marker unique to endospores. An improvement on the current bacterial spore detection assay based on sensitized lanthanide luminescence is presented through the implementation of a dipicolinate-specific Tb<sup>3+</sup> receptor site. The use of
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Book chapters on the topic "MLC601"

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Deng, Maoxian, Lixia Deng, and Yarong Xue. "MAP Kinase-Mediated and MLCK-Independent Phosphorylation of MLC20 in Smooth Muscle Cells." In Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues - From Molecules to Humans. InTech, 2012. http://dx.doi.org/10.5772/47732.

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Conference papers on the topic "MLC601"

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Mantovanélli, Mauro, and Pedro Henrique Del Caro Daher. "DECAPAGEM DO SISTEMA DE RESFRIAMENTO SECUNDÁRIO DA MLC1 DA ARCELORMITTAL TUBARÃO1." In 66º Congresso Anual da ABM. Editora Blucher, 2011. https://doi.org/10.5151/2594-5327-17817.

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