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Relevant bibliographies by topics / MLS-resistance

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Academic literature on the topic 'MLS-resistance'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "MLS-resistance"

1

Abu Lila, Amr Selim, Tareq Nafea Alharby, Jowaher Alanazi, et al. "Clinical Resistant Strains of Enterococci and Their Correlation to Reduced Susceptibility to Biocides: Phenotypic and Genotypic Analysis of Macrolides, Lincosamides, and Streptogramins." Antibiotics 12, no. 3 (2023): 461. http://dx.doi.org/10.3390/antibiotics12030461.

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Enterococci are troublesome nosocomial, opportunistic Gram-positive cocci bacteria showing enhanced resistance to many commonly used antibiotics. This study aims to investigate the prevalence and genetic basis of antibiotic resistance to macrolides, lincosamides, and streptogramins (MLS) in Enterococci, as well as the correlation between MLS resistance and biocide resistance. From 913 clinical isolates collected from King Khalid Hospital, Hail, Saudi Arabia, 131 isolates were identified as Enterococci spp. The susceptibility of the clinical enterococcal isolates to several MLS antibiotics was

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2

Wang, Ge, and Diane E. Taylor. "Site-Specific Mutations in the 23S rRNA Gene ofHelicobacter pylori Confer Two Types of Resistance to Macrolide-Lincosamide-Streptogramin B Antibiotics." Antimicrobial Agents and Chemotherapy 42, no. 8 (1998): 1952–58. http://dx.doi.org/10.1128/aac.42.8.1952.

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ABSTRACT Clarithromycin resistance in Helicobacter pylori is mainly due to A-to-G mutations within the peptidyltransferase region of the 23S rRNA. In the present study, cross-resistance to macrolide, lincosamide, and streptogramin B (MLS) antibiotics (MLS phenotypes) has been investigated for several clinical isolates of H. pylori. Two major types of MLS resistance were identified and correlated with specific point mutations in the 23S rRNA gene. The A2142G mutation was linked with high-level cross-resistance to all MLS antibiotics (type I), and the A2143G mutation gave rise to an intermediate

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3

Pernodet, J. L., S. Fish, M. H. Blondelet-Rouault, and E. Cundliffe. "The macrolide-lincosamide-streptogramin B resistance phenotypes characterized by using a specifically deleted, antibiotic-sensitive strain of Streptomyces lividans." Antimicrobial Agents and Chemotherapy 40, no. 3 (1996): 581–85. http://dx.doi.org/10.1128/aac.40.3.581.

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Genes conferring resistance to macrolide, lincosamide, and streptogramin B (MLS) antibiotics via ribosomal modification are widespread in bacteria, including clinical isolates and MLS-producing actinomycetes. Such erm-type genes encode enzymes that mono- or dimethylate residue A-2058 of 23S rRNA. The different phenotypes resulting from monomethylation (MLS-I phenotype, conferred by erm type I genes) or dimethylation (MLS-II phenotype due to erm type II genes) have been characterized by introducing tlrD or ermE, respectively, into an MLS-sensitive derivative of Streptomyces lividans TK21. This

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Wordell Filho, João Américo, Rafael Dal Bosco Ducatti, and Cristiano Nunes Nesi. "Resistance of Brazilian commercially grown maize genotypes to Macrospora Leaf Spot." Acta Scientiarum. Agronomy 46, no. 1 (2023): e63370. http://dx.doi.org/10.4025/actasciagron.v46i1.63370.

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Macrospora leaf spot (MLS), caused by the fungus Stenocarpella macrospora, is one of the most important diseases affecting maize in Brazil. However, there are no MLS-resistant cultivars commercially available. Therefore, this study aimed to investigate the lesion expansion rate of MLS in four maize genotypes, leaf wetness duration (0-, 6-, 12-, 18-, 24-, 30-, 36-, 42-, and 54-hour post-inoculation), disease development severity in three maize genotypes, and resistance/tolerance levels to MLS in 141 maize genotypes commercially grown in Brazil. The estimates were performed using logistic models

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5

Duval, J. "Evolution and epidemiology of MLS resistance." Journal of Antimicrobial Chemotherapy 16, suppl A (1985): 137–49. http://dx.doi.org/10.1093/jac/16.suppl_a.137.

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6

Liu, Liyong, Caixin Xiang, Yiwei Zhang, et al. "A Novel Detection Procedure for Mutations in the 23S rRNA Gene of Macrolide-Resistant Mycoplasma pneumoniae with Two Non-Overlapping Probes Amplification Assay." Microorganisms 12, no. 1 (2023): 62. http://dx.doi.org/10.3390/microorganisms12010062.

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Mycoplasma pneumoniae is a significant cause of community-acquired pneumonia, which is often empirically treated with macrolides (MLs), but, presently, resistance to MLs has been a matter of close clinical concern. This assay is intended to contribute to resistance detection of M. pneumoniae in clinical practice. A novel real-time PCR assay with two non-overlapping probes on the same nucleic acid strand was designed in this study. It could effectively detect all mutation types of M. pneumoniae in 23S rRNA at loci 2063 and 2064. The results were determined by the following methods: ΔCT < 0.5

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7

Hsueh, Po-Ren, Lee-Jene Teng, Li-Na Lee, Shen-Wu Ho, Pan-Chyr Yang, and Kwen-Tay Luh. "High Incidence of Erythromycin Resistance among Clinical Isolates of Streptococcus agalactiae in Taiwan." Antimicrobial Agents and Chemotherapy 45, no. 11 (2001): 3205–8. http://dx.doi.org/10.1128/aac.45.11.3205-3208.2001.

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ABSTRACT The in vitro susceptibilities of 266 isolates ofStreptococcus agalactiae determined by the agar dilution method showed that 6% of isolates were nonsusceptible to penicillin and 46% was resistant to erythromycin. Of the erythromycin-resistant isolates, 86.3% had the macrolide-lincosamide-streptogramin (MLS) resistance phenotype (constitutive MLS, 85.5%; inducible MLS, 0.8%) and 13.7% had the M phenotype.

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8

Al-Salmani, Tuqa S., and Mustafa M. Al-Qaisi. "Phenotypic Detection of Macrolide-Lincosamide-Streptogramin Resistance among Staphylococcus aureus and Staphylococcus epidermidis in Baghdad, Iraq." International Journal of Drug Delivery Technology 10, no. 03 (2020): 431–36. http://dx.doi.org/10.25258/ijddt.10.3.22.

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Introduction: Staphylococci emerged as the most frequent nosocomial and community-acquired pathogens. Macrolide-lincosamide-streptogramin (MLS) antibiotics resistance was increasing among Staphylococcus aureus and Staphylococcus epidermidis (S. epidermidis) isolates. Objective: In the present study, the aim was to detect the phenotypic resistance pattern of MLS (constitutive and inducible) among S. aureus and S. epidermidis isolated from Iraqi patients. Methods: A total of 120 staphylococcal isolates (60 S. aureus and 60 S. epidermidis) were isolated from urine, wound swab, blood, and sputum s

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9

Farrow, Kylie A., Dena Lyras, and Julian I. Rood. "The Macrolide-Lincosamide-Streptogramin B Resistance Determinant from Clostridium difficile 630 Contains Two erm(B) Genes." Antimicrobial Agents and Chemotherapy 44, no. 2 (2000): 411–13. http://dx.doi.org/10.1128/aac.44.2.411-413.2000.

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ABSTRACT The ErmB macrolide-lincosamide-streptogramin B (MLS) resistance determinant from Clostridium difficile 630 contains two copies of an erm(B) gene, separated by a 1.34-kb direct repeat also found in an Erm(B) determinant from Clostridium perfringens. In addition, both erm(B) genes are flanked by variants of the direct repeat sequence. This genetic arrangement is novel for an ErmB MLS resistance determinant.

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McDougal, Linda K., Fred C. Tenover, Linda N. Lee, et al. "Detection of Tn917-Like Sequences within a Tn916-like Conjugative Transposon (Tn3872) in Erythromycin-Resistant Isolates of Streptococcus pneumoniae." Antimicrobial Agents and Chemotherapy 42, no. 9 (1998): 2312–18. http://dx.doi.org/10.1128/aac.42.9.2312.

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ABSTRACT A series of macrolide-lincosamide-streptogramin B (MLS)-resistant pneumococcal isolates of a variety of serotypes was examined and was found to contain Tn917-like elements by DNA-DNA hybridization. Like Tn1545, Tn917 also encodes an ermAM gene but does not mediate resistance to other antimicrobial agents. Furthermore, nucleotide sequence analyses of the DNAs flanking three of the Tn917-like elements revealed that they were inserted into orf9 of a Tn916-like element in a composite transposon-like structure (Tn3872). Other MLS-resistant strains appeared to contain Tn1545-like elements t

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Dissertations / Theses on the topic "MLS-resistance"

1

Farrow, Kylie Ann 1973. "Analysis of clostridial MLS resistance determinants." Monash University, Dept. of Microbiology, 2001. http://arrow.monash.edu.au/hdl/1959.1/8319.

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2

VERDIER, LAURENT. "Etude de l'interaction entre les antibiotiques mls b et les ribosomes bacteriens par rmn et modelisation moleculaire. Application a un phenomene de resistance antibiotique." Paris 7, 2001. http://www.theses.fr/2001PA077118.

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Les macrolides, lincosamides et streptogramines b (mls b) sont des antibiotiques qui inhibent la biosynthese proteique pendant la phase d'elongation en se fixant sur la sous-unite ribosomale 50s. L'interaction de ces molecules sur le ribosome comporte deux etapes : = > une interaction faible qui peut etre detectee et mesuree par rmn = > une interaction forte (k d = 10 7 10 9 m) detectee par des tests biologiques (tests de binding) mais possedant une trop forte affinite pour etre caracterisee en rmn. L'interaction faible observee par rmn serait precurseur de l'interaction forte. Cette interacti

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Book chapters on the topic "MLS-resistance"

1

Macrina, Francis L., and C. Jeffrey Smith. "Gene Transmission, MLS, and Tetracycline Resistance in Bacteroides." In Brock/Springer Series in Contemporary Bioscience. Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4615-7087-5_35.

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Huang A.B., Huang Y.T., and Ho F.J. "Assessment of liquefaction potential for a silty sand in Central Western Taiwan." In Proceedings of the 16th International Conference on Soil Mechanics and Geotechnical Engineering. IOS Press, 2005. https://doi.org/10.3233/978-1-61499-656-9-2653.

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The Chi Chi earthquake of September 21, 1999 triggered extensive soil liquefaction in silty sand deposits in Central Western Taiwan. The post Chi Chi earthquake studies indicated that the fines content adjustments according to the simplified procedure could cause rather inconsistent results amongst various assessment methods. The authors performed a series of cone penetration chamber calibration tests and cyclic triaxial tests on remolded Mai Liao Sand (MLS) specimens, with various fines contents and densities. The triaxial cell was equipped with bender elements and shear wave velocity (Vs) wa

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Conference papers on the topic "MLS-resistance"

1

He, D. Y., F. Y. Zhang, J. M. Jiang, B. Y. Fu, and X. Y. Li. "Study on Iron Based Arc Spraying Cored Wire with TiC Ceramic Powders." In ITSC2007, edited by B. R. Marple, M. M. Hyland, Y. C. Lau, C. J. Li, R. S. Lima, and G. Montavon. ASM International, 2007. http://dx.doi.org/10.31399/asm.cp.itsc2007p1145.

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Abstract Iron base composite coatings were deposited on mild steel substrates by arc spraying and cored wire with TiC ceramic powders. The abrasive wear resistance properties were examined on the MLS-225 wet sand/rubber wheel tester. The microstructure, phase compositions and worn surface morphologies of the coatings were observed by means of optical, scanning electron microscopy and X-ray diffraction. The results showed that composite coatings with TiC ceramic hard phases were reinforced by the TiC hard particles distributed in the iron-based coating. The average micro hardness of the coating

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2

He, D. Y., B. Y. Fu, J. M. Jiang, and X. Y. Li. "Study on Abrasive Resistance of Arc Spraying Fe-Based Coatings Containing Cr3C2 Hard Phase." In ITSC2007, edited by B. R. Marple, M. M. Hyland, Y. C. Lau, C. J. Li, R. S. Lima, and G. Montavon. ASM International, 2007. http://dx.doi.org/10.31399/asm.cp.itsc2007p1135.

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Abstract Thermal spray processes are widely used to protect materials and components against wear, corrosion and oxidation. As commercial arc sprayed coatings have been used to a limited extent in applications involving erosion and abrasion wear, developing attractive wear resistance arc sprayed coatings has been found necessary. Abrasive wear testing was carried out on four Fe-based composite coatings containing varied contents of Cr3C2 particles as hard phases. Scanning electron microscopy (SEM) was used for observing the surfaces of the composite coatings, and wear mechanisms of the coating

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