Relevant bibliographies by topics / MMVs

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'MMVs'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 February 2022

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Journal articles on the topic "MMVs"

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Shekaramiz, Mohammad, Todd Moon, and Jacob Gunther. "Bayesian Compressive Sensing of Sparse Signals with Unknown Clustering Patterns." Entropy 21, no. 3 (2019): 247. http://dx.doi.org/10.3390/e21030247.

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We consider the sparse recovery problem of signals with an unknown clustering pattern in the context of multiple measurement vectors (MMVs) using the compressive sensing (CS) technique. For many MMVs in practice, the solution matrix exhibits some sort of clustered sparsity pattern, or clumpy behavior, along each column, as well as joint sparsity across the columns. In this paper, we propose a new sparse Bayesian learning (SBL) method that incorporates a total variation-like prior as a measure of the overall clustering pattern in the solution. We further incorporate a parameter in this prior to account for the emphasis on the amount of clumpiness in the supports of the solution to improve the recovery performance of sparse signals with an unknown clustering pattern. This parameter does not exist in the other existing algorithms and is learned via our hierarchical SBL algorithm. While the proposed algorithm is constructed for the MMVs, it can also be applied to the single measurement vector (SMV) problems. Simulation results show the effectiveness of our algorithm compared to other algorithms for both SMV and MMVs.
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Ballout, Ali, Alia Ghaddar, and Houssein Wehbi. "MMVS/COE: mobile multi-view video streaming with constant order encoding." Multimedia Tools and Applications 78, no. 8 (2018): 10753–72. http://dx.doi.org/10.1007/s11042-018-6564-6.

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Nielsen, M. H., H. Irvine, S. Vedel, B. Raungaard, H. Beck-Nielsen, and A. Handberg. "The Impact of Lipoprotein-Associated Oxidative Stress on Cell-Specific Microvesicle Release in Patients with Familial Hypercholesterolemia." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/2492858.

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Objective. Microvesicles (MVs) are small cell-derived particles shed upon activation. Familial hypercholesterolemia (FH) particularly when associated with Achilles tendon xanthomas (ATX) predisposes to atherosclerosis, possibly through oxLDL-C interaction with the CD36 receptor. To investigate the hypothesis that MVs derived from cells involved in atherosclerosis are increased in FH and that CD36 expressing MVs (CD36+ MVs) may be markers of oxLDL-C-induced cell activation, cell-specific MVs were measured in FH patients with and without ATX and their association with atherogenic lipid profile was studied.Approach and Results. Thirty FH patients with and without ATX and twenty-three controls were included. Plasma concentrations of MVs and CD36+ MVs derived from platelets (PMVs), erythrocytes (ErytMVs), monocytes (MMVs), and endothelial cells (EMVs), as well as tissue factor-positive cells (TF+ MVs), were measured by flow cytometry. Total MVs, MMVs, EMVs, ErytMVs, and TF+ MVs were significantly increased in FH patients, compared to controls. CD36+ MVs derived from endothelial cells and monocytes were significantly higher in FH patients and oxLDL-C predicted all the investigated cell-specific CD36+ MVs in FH patients with ATX.Conclusions. MVs derived from cells involved in atherosclerosis were increased in FH and may contribute to elevated atherothrombosis risk. The increased cell-specific CD36+ MVs observed in FH may represent markers of oxLDL-C-induced cell activation.
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Upadhyay, Deepika, Geetanjali Purswani, and Pooja Jain. "Yulu: Moving Towards a Sustainable Future." South Asian Journal of Business and Management Cases 9, no. 3 (2020): 445–56. http://dx.doi.org/10.1177/2277977920957954.

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The rapidly rising rate of urbanization, which is closely linked to economic growth, has exposed the world to several challenges such as inequality, environmental degradation, traffic congestion, infrastructural concerns and social conflicts. Therefore, urban sustainability has emerged as one of the most debatable discussions across the world. The existing network of transportation can no longer keep up with the growing demand in metropolitan cities. Short distance travel has become an unresolved issue for daily commuters. The case presents how MMVs have emerged as an alternative mode of transport for resolving issues of daily commuters regarding the first-mile connectivity, last-mile connectivity and short distance travel to reach their final destination. MMVs are basically light-weight vehicles which occupy less space on road. These vehicles include bicycles, e-bikes, skateboards, hoverboards and other battery-operated vehicles. The case narrates the journey of Yulu, a dockless bike-sharing venture which promoted the concept of green consumerism among the daily commuters at affordable rates. The venture initially started in the IT city of Bangalore and later expanded its operations to other cities such as Pune, Navi Mumbai, Gurugram and Bhubaneswar. The speciality of this venture is that it offers a sustainable solution to ever-increasing problems of traffic congestion and aggravating air pollution issues in metropolitan cities. Dilemma: How to offer a sustainable solution to the ever-increasing problem of traffic congestion and aggravating air pollution due to rising vehicular traffic? How to make short distance travel affordable and more convenient for daily commuters? Theory: Three pillars of sustainable development. Type of Case: Problem solving applied case. Protagonist: Present. Discussion and Case Questions: What strategies should be employed by the start-up to make it a more popular form of commute? How can the increasing rate of damage to the vehicles be brought down? How does organization structure and cluster management practices of Yulu help it to become more sustainable? How can the regulatory bodies and government promote and adopt such start-ups in their urban planning projects?
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Deng, Xiaofeng, Zihao Zhang, Yan Zhang, et al. "Comparison of 7.0- and 3.0-T MRI and MRA in ischemic-type moyamoya disease: preliminary experience." Journal of Neurosurgery 124, no. 6 (2016): 1716–25. http://dx.doi.org/10.3171/2015.5.jns15767.

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OBJECT The authors compared the image quality and diagnostic sensitivity and specificity of 7.0-T and 3.0-T MRI and time-of-flight (TOF) MR angiography (MRA) in patients with moyamoya disease (MMD). METHODS MR images of 15 patients with ischemic-type MMD (8 males, 7 females; age 13–48 years) and 13 healthy controls (7 males, 6 females; age 19–28 years) who underwent both 7.0-T and 3.0-T MRI and MRA were studied retrospectively. The main intracranial arteries were assessed by using the modified Houkin’s grading system (MRA score). Moyamoya vessels (MMVs) were evaluated by 2 grading systems: the MMV quality score and the MMV area score. Two diagnostic criteria for MMD were used: the T2 criteria, which used flow voids in the basal ganglion on T2-weighted images, and the TOF criteria, which used the high-intensity areas in the basal ganglion on source images from TOF MRA. All data were evaluated by 2 independent readers who were blinded to the strength field and presence or absence of MMD. Using conventional angiography as the gold standard, the sensitivity and specificity of 7.0-T and 3.0-T MRI/MRA in the diagnosis of MMD were calculated. The differences between 7.0-T and 3.0-T MRI and MRA were statistically compared. RESULTS No significant differences were observed between 7.0-T and 3.0-T MRA in MRA score (p = 0.317) or MRA grade (p = 0.317). There was a strong correlation between the Suzuki’s stage and MRA grade in both 3.0-T (rs = 0.930; p < 0.001) and 7.0-T (rs = 0.966; p < 0.001) MRA. However, MMVs were visualized significantly better on 7.0-T than on 3.0-T MRA, suggested by both the MMV quality score (p = 0.001) and the MMV area score (p = 0.001). The correlation between the Suzuki’s stage and the MMV area score was moderate in 3.0-T MRA (rs = 0.738; p = 0.002) and strong in 7.0-T MRA (rs = 0.908; p < 0.001). Moreover, 7.0-T MR images showed a greater capacity for detecting flow voids in the basal ganglion on both T2-weighted MR images (p < 0.001) and TOF source images (p < 0.001); 7.0-T MRA also revealed the subbranches of superficial temporal arteries much better. Receiver operating characteristic curve analysis showed that, according to the T2 criteria, 7.0-T MRI/MRA was more sensitive (sensitivity 1.000; specificity 0.933) than 3.0-T MRI/MRA (sensitivity 0.692; specificity 0.933) in diagnosing MMD; based on the TOF criteria, 7.0-T MRI/MRA was more sensitive (1.000 vs 0.733, respectively) and more specific (1.000 vs 0.923, respectively) than 3.0-T MRI/MRA. CONCLUSIONS Compared with 3.0-T MRI/MRA, 7.0-T MRI/MRA detected and delineated MMVs more clearly and provided higher diagnostic sensitivity and specificity, although it did not show significant improvement in depicting main intracranial arteries. The authors speculate that 7.0-T MRI/MRA is a promising technique in the diagnosis of MMD because it is noninvasive compared with conventional angiography and it is more sensitive than 3.0-T MRI/MRA.
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Gaffney-Stomberg, Erin, Ben-hua Sun, Carrie E. Cucchi, et al. "The Effect of Dietary Protein on Intestinal Calcium Absorption in Rats." Endocrinology 151, no. 3 (2010): 1071–78. http://dx.doi.org/10.1210/en.2009-0744.

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Increasing dietary protein intake in humans acutely increases urinary calcium. Isotopic absorption studies have indicated that, at least in the short term, this is primarily due to increased intestinal Ca absorption. To explore the mechanisms underlying dietary protein’s effect on intestinal Ca absorption, female Sprague Dawley rats were fed a control (20%), low (5%), or high (40%) protein diet for 7 d, and Ca balance was measured during d 4–7. On d 7, duodenal mucosa was harvested and brush border membrane vesicles (BBMVs) were prepared to evaluate Ca uptake. By d 7, urinary calcium was more than 2-fold higher in the 40% protein group compared with control (4.2 mg/d vs. 1.7 mg/d; P < 0.05). Rats consuming the 40% protein diet both absorbed and retained more Ca compared with the 5% protein group (absorption: 48.5% vs. 34.1% and retention: 45.8% vs. 33.7%, respectively; P < 0.01). Ca uptake was increased in BBMVs prepared from rats consuming the high-protein diet. Maximum velocity (Vmax) was higher in the BBMVs prepared from the high-protein group compared with those from the low-protein group (90 vs. 36 nmol Ca/mg protein · min, P < 0.001; 95% CI: 46–2486 and 14–55, respectively). The Michaelis Menten constant (Km) was unchanged (2.2 mmvs. 1.8 mm, respectively; P = 0.19). We conclude that in rats, as in humans, acute increases in protein intake result in hypercalciuria due to augmented intestinal Ca absorption. BBMV Ca uptake studies suggest that higher protein intake improves Ca absorption, at least in part, by increasing transcellular Ca uptake.
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Dubois, Mathilde, Pierre Vacher, Benoı̂t Roger, et al. "Glucotoxicity Inhibits Late Steps of Insulin Exocytosis." Endocrinology 148, no. 4 (2007): 1605–14. http://dx.doi.org/10.1210/en.2006-1022.

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Prolonged exposure of β-cells to high glucose (glucotoxicity) diminishes insulin secretion in response to glucose and has been linked to altered generation of metabolism-secretion coupling factors. We have investigated whether glucotoxicity may also alter calcium handling and late steps in secretion such as exocytosis. Clonal INS-1E β-cells cultured at high glucose (20 or 30 mmvs. 5.5 mm) for 72 h exhibited elevated basal intracellular calcium ([Ca2+]i), which was KATP-channel dependent and due to long-term activation of protein kinase A. An increased amplitude and shortened duration of depolarization-evoked rises in [Ca2+]i were apparent. These changes were probably linked to the observed increased filling of intracellular stores and to short-term activation of protein kinase A. Insulin secretion was reduced not only by acute stimulation with either glucose or KCl but more importantly by direct calcium stimulation of permeabilized cells. These findings indicate a defect in the final steps of exocytosis. To confirm this, we measured expression levels of some 30 proteins implicated in trafficking/exocytosis of post-Golgi vesicles. Several proteins required for calcium-induced exocytosis of secretory granules were down-regulated, such as the soluble N-ethylmaleimide-sensitive factor-sensitive factor attachment receptor (SNARE) proteins VAMP-2 [vesicle (v)-SNARE, vesicle-associated membrane protein 2] and syntaxin 1 as well as complexin. VAMP-2 was also reduced in human islets. In contrast, cell immunostaining and expression levels of several fluorescent proteins suggested that other post-trans-Golgi trafficking steps and compartments are preserved and that cells were not degranulated. Thus, these studies indicate that, in addition to known metabolic changes, glucotoxicity impedes generation of signals for secretion and diminishes the efficiency of late steps in exocytosis.
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Kordy, Kariman, Aliaa Bassiouny, and Eskandar Tooma. "Valuation discrepancies in money market funds during market disruptions: evidence from Egypt." Investment Management and Financial Innovations 17, no. 3 (2020): 97–110. http://dx.doi.org/10.21511/imfi.17(3).2020.08.

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Money market funds (MMFs) are generally considered safe investment vehicles, but the 2008 global financial crisis showed their vulnerability during market disruptions resulting in increased regulatory oversight across developed markets to protect investors. This paper examines the effect of MMF accounting regulation on investors in an emerging market context. It hypothesizes that the continued use of amortized cost methods to account for MMFs’ Net Asset Value (NAV) during market disruptions can result in unfair treatment of investors. The Egyptian money market provided a unique laboratory to test this hypothesis over a prominent economic crisis that combined high levels of interest rate volatility with a redemption-only structure for MMFs. A model that measures the discrepancies between the amortized and floating market NAVs per certificate for various money market portfolios (MMPs) simulating MMFs of different durations is tested using the Egyptian data. A sharp rise in interest rates is found to lead to significant discrepancies between the amortized NAV per certificate relative to their floating value. Serial investor redemptions of the certificates compound the discrepancies, but only certificate holders remaining in the funds bear the accumulated losses, which are augmented for portfolios with higher durations. The results suggest that emerging market regulators consider introducing the rules that switch to floating NAV calculations for MMFs during such periods to promote equality across all investors.
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Boushell, Lee W., and Edward J. Swift. "MMPs." Journal of Esthetic and Restorative Dentistry 25, no. 4 (2013): 217–18. http://dx.doi.org/10.1111/jerd.12044.

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Dong, Mengmeng, Enfan Zhang, Haimeng Yan, et al. "Macrophages Promote DNA Repair of Double Strand Break in Multiple Myeloma Cells By Non-Homologous End Joining(NHEJ), Nevertheless Decrease Its Accuracy." Blood 134, Supplement_1 (2019): 3087. http://dx.doi.org/10.1182/blood-2019-126753.

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Multiple myeloma (MM) is a hematological malignancy of B cells, characterized by clonal proliferation of malignant plasma cells. DNA damage and genomic instability play an important role in the pathogenesis of MM. Based on the characteristics of high heterogeneity and genomic instability of MM, and the protective effect of MΦs on MM cells (MMCs), our study intended to further clarify whether MΦs affect MMCs DNA damage response (DDR) and DNA repair, and the relationship between MΦs and genomic instability of MMCs. We found that the content of MΦs in bone marrow biopsy of MM patients was related to the results of cytogenetics (tested by FISH). The higher the content of MΦs, the more complicated the cytogenetic abnormalities of patients, especially in the IgH translocation, D13S319 locus deletion and RB1 deletion. In our study, MΦs were harvested from peripheral blood monocytes (PBMCs) , which were incubated for 7 days with M-CSF. Flow cytometry was used to detect M-CSF induced macrophages (MΦs) in vitro, and CD163 and CD206 were highly expressed in MΦs which implied that MΦs tended to be M2 type. The incubated MΦs were used in the following experiments. Our study showed that MΦs reduced the baseline γH2AX of MMCs, and contributed to MMCs surviving in the case of genomic instability detected by Western blot and immunofluorescence. We also confirmed that MΦs contribute to repairing the DNA damage in myeloma cells with the methods of comet assay. In the case of severe injury of MMCs' DNA, MΦs promoted the DDR and DNA damage repair. We examined the effects of macrophages on HR and NHEJ using U2OS cells. HR repair was measured in U2OS-HR cells loaded with SCR reporter (HR reporter) while NHEJ repair was measured in U2OS-NHEJ cells loaded with vGEJ reporter (NHEJ Reporter). We found that macrophages increased NHEJ but had no sense on total HR. In order to detect NHEJ level in endogenous genes, we adopted paired gRNA-CRISPR/Cas9 system. AAVS1 and HBB were used as detection genes, and the sequence of about 250 bp near the NHEJ interface was sequenced by NGS. The results proclaimed that the MΦs co-culture group significantly increased the efficiency of NHEJ, and decreased proportion of accurate NHEJ repair. In addition, analysis of the length of base sequence loss showed that the probability of base loss >3 bp in the MΦs co-culture group was higher than that MMCs in the group cultured alone. In the HBB site, MΦs also prolonged the average length of base loss in NHEJ. Furthermore, we used gRNA-CRISPR/Cas9 technology to cause fixed-point cleavage in AAVS1 and HBB respectively, and detected translocation by PCR and NGS with comparing the translocation reads between different groups. The results showed that MΦs promoted the probability of chromosomal translocation, which was of great importance in MM's occurrence and progression. Disclosures No relevant conflicts of interest to declare.
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Dissertations / Theses on the topic "MMVs"

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Reis, Elizete de Moraes. "EFEITO DO Hypericum perforatum EM DIFERENTES MODELOS DE DESORDENS MOTORAS EM RATOS." Universidade Federal de Santa Maria, 2013. http://repositorio.ufsm.br/handle/1/9016.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Abnormal movements are clinical symptoms present in neurodegenerative diseases, such Parkinsonism , as well as Tardive dyskinesia. It is thought that unbalance in monoamine levels with their consequent metabolism could be involved in the etiology of these abnormal movements. However, until this moment there is not efficacious treatment with low side effects for these conditions. In this context, Hypericum perforatum (H. perforatum), popularly known as St. John s Wort, is a plant largely used as antidepressant and presenting high amount of polyphenol constituents. Its antidepressant mechanism seems to involve the increase of monoamines and monoaminoxidase inhibition. Here, we evaluated the effect of H. perforatum on different models of abnormal movements in rats, either using fluphenazine or reserpine. It were quantified the number of vacuous chewing movements (VCMs) and locomotor activity (number or rearings and crossings) in both models. In experiment 1, rats received a single administration of fluphenazine enantate (25 mg/Kg, i.m.) and/or H. perforatum (300 mg/Kg, in place of drinking water) during 7 days. Fluphenazine treatment increased VCMs and decreased the locomotor activity after 7 days of treatment. However, H. perforatum did not alter either the number of VCMs or the locomotor activity (represented by number of crossing and rearing in the open field test) in rats. In experiment 2, rats received reserpine administration once a day during 3 days (0.5 mg/Kg, s.c.) and/or H. perforatum (300 mg/Kg, in place of drinking water) during 16 days. Reserpine treatment increased VCMs and decreased the locomotor activity. H. perforatum did not alter the number of VCMs or the number of rearing. However, H. perforatum co-treatment could avoid the effect of reserpine on number of crossings. In conclusion, H. perforatum did not seem to be efficacious to protect against orofacial movements induced by fluphenazine or reserpine in rats.<br>As desordens motoras são sintomas de doenças neurodegenerativas bem como podem estar associadas ao tratamento com antipsicóticos. Cita-se como exemplo destas desordens, sintomas da Doença de Parkinson (DP) e a Discinesia Tardia (DT), respectivamente. O desequilíbrio cerebral nos níveis de monoaminas e, consequentemente, seu metabolismo tem sido relacionados ao desenvolvimento dos movimentos anormais que aparecem nas desordens motoras, tendo em vista que os circuitos dopaminérgicos estão envolvidos na gênese da DP e da DT. No entanto, ainda não existem tratamentos eficazes e com poucos efeitos colaterais para tais condições. A Hypericum perforatum (H. perforatum), popularmente conhecido como Erva de São João, consiste numa planta amplamente utilizada como antidepressiva e que possui uma grande quantidade de compostos fenólicos, cujo mecanismo para esta atividade está relacionado à inibição da monoamina oxidade (MAO) e da recaptação de monoaminas cerebrais. Assim, o objetivo do presente estudo foi investigar o efeito do H. perforatum em modelos de desordem motora induzida por flufenazina ou reserpina em ratos. Foram quantificados os movimentos de mascar no vazio (MMV) e atividade locomotora (cruzamentos e levantadas observados no teste de campo aberto) em ambos os modelos. No experimento 1, os ratos receberam uma única administração de enantato de flufenazina (25 mg/Kg, i.m.) e ou H. perforatum (300 mg/Kg, no lugar da água de beber) durante 7 dias. O tratamento com flufenazina aumentou o número de MMVs e diminuiu a atividade locomotora em ratos após 7 dias de tratamento. No entanto, o tratamento com H. perforatum não protegeu das alterações comportamentais causadas pelo tratamento com flufenazina. No experimento 2, os ratos receberam água ou H. perforatum (300 mg/Kg, no lugar da água de beber) durante 16 dias. A partir do dia 9 de tratamento os animais receberam uma administração diária de reserpina (0,5 mg/Kg, s.c.) ou veículo durante 3 dias com intervalo de 48 horas. A reserpina aumentou o número MMVs e diminuiu a atividade locomotora em campo aberto. O prétratamento com H. perforatum não alterou o efeito da reserpina sobre o número de MMVs e levantadas. Porém, o pré-tratamento com H. perforatum preveniu o efeito da reserpina sobre número de cruzamentos. Desta forma, podemos concluir que o H. perforatum não apresentou efeito benéfico sobre os movimentos orofaciais induzidos por flufenazina ou reserpina em ratos.
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Ylipalosaari, M. (Merja). "Matrix metalloproteinases (MMPs) in oral carcinomas." Doctoral thesis, University of Oulu, 2005. http://urn.fi/urn:isbn:9514277309.

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Abstract Matrix metalloproteinases, MMPs, are a family of enzymes capable of modulating connective tissue components. The expression of several MMPs is increased in oral squamous cell carcinomas (OSCCs). They are assumed to have an important role in the development and progression of OSCCs. However, the exact role and mechanism of the regulation of MMPs in malignant transformation are still largely unknown. In this study, tumour-associated trypsin-2 (TAT-2) was detected in OSCC tissue sections, and its role in MMP-2 and -9 regulation in carcinoma cells was evaluated. The TAT-2 gene was transfected into two different OSCC cell lines and one immortalized oral epithelial cell line. In TAT-2-transfected cells, MMP-9 activation increased OSCC cell invasion in chicken chorionallantoic membrane assay. Increased intravasation was prevented by tumour-associated trypsin inhibitor or specific gelatinase-inhibiting CTT-peptide. TAT-2 also converted MMP-1, -8, -13 and -3 into smaller molecular weight forms in vitro. However, TAT-2-transfected OSCC cells showed no conversion. TAT-2 was demonstrated to degrade powerfully type I collagen into small fragments in vitro. The cell surface receptor αvβ6 integrin is strongly up-regulated in OSCCs. By using β6-transfected OSCC cells, it was demonstrated that αvβ6 integrin down-regulates MMP-13 expression. However, this integrin did not regulate other collagenases or TIMP-1. β6-transfected cells invaded more efficiently through the basement membrane matrix, but their migration through type I collagen remained unchanged. MMP-8 expression was detected for the first time in head and neck squamous cell carcinoma (HNSCC) cell lines and corresponding cultured dermal and tumour fibroblasts. The localization of MMP-8 in HNSCC was determined by immunohistochemical stainings and in situ hybridization. MMP-8 production levels in carcinoma cells were faint and sporadic in HNSCCs sections. Ninety-two primary mobile tongue SCCs were subjected to MMP-8 immunohistochemical staining, and the staining results were compared to survival rates. MMP-8 was associated with improved disease-free survival in females but not in males.
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Lemnifi, Ahmed. "Influence of excimer laser surface melting on microstructure and corrosion behaviour of AA6061-T6 alloy and SiCp/AA6061-T6 composite." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/influence-of-excimer-laser-surface-melting-on-microstructure-and-corrosion-behaviour-of-aa6061t6-alloy-and-sicpaa6061t6-composite(5b945607-0479-411b-bb08-61e3c96a606e).html.

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This thesis presents an investigation of excimer laser surface melting (LSM) on AA6061-T6 alloy and SiCp/AA6061-T6 composite in terms of microstructure and corrosion behaviour. Hardness and wear resistance of the melted layer for both materials were also evaluated and compared with the untreated specimen to understand if the improvement of the corrosion resistance could be achieved without sacrificing the wear resistance. The intermetallic particles within the aluminium matrix are believed to initiate of both galvanic and pitting corrosion for both materials. To effectively dissolve these intermetallic particles, laser fluence from 1 to 8.5 J/cm2 with a number of pulses from 10, 25 to 50 were selected to achieve an optimisation of the LSM condition. It was found that the increase of laser fluence increased the melt depth, but also promoted the formation of defects such as micro-cracks and pores. For AA6061-T6 alloy, under the best laser condition (3 J/cm2 with 50 pulses), the amount of large intermetallic particles (2-10 µm), such as AlFeSi, AlFeMnSi and Mg2Si, were significantly reduced resulting in the formation of a relatively homogeneous and defect-free melt layer with only some small randomly distributed of intermetallic precipitates. For the SiCp/AA6061-T6 composite, under the best laser condition (6 J/cm2 with 25 pulses), decomposition of SiC particles was achieved as well as the dissolution of large AlMgSiCr and AlFeSi intermetallic particles in the melt layer. The melt layer had a relatively complex microstructure consisting of three different regions. MgO was found at the bottom of the melted layer which was discontinuous along the interface between the melted region and bulk material or in some places, at the bottom of the melted layer. The corrosion behaviour of both materials before and after LSM was evaluated using electrochemical measurements and immersion test in deaerated 0.6 M NaCl solution. After LSM the AA6061-T6 with and without SiC showed a better corrosion resistance compared with untreated alloys. The pitting potential of the LSM for both materials was shifted to a more positive value with a significant reduction of the passivation current density. In addition, an intergranular corrosion test based on the standard ASTM G110-92 showed that the LSM had significantly improved the corrosion resistance of both materials due to dissolution of intermetallic particles as well as the removal of the SiC particles in the composite material within the melted regions. In addition, the wear resistance of as-received SiCp/AA6061-T6 composites was found to be much higher than that of the LSM specimen. This is attributed to the decomposition of the majority of the SiCp in the melted region since the contribution to the hardness from the SiC particle in the untreated specimen is much greater that the Si-rich region in the melt layer after LSM.
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Bourd-Boittin, Katia. "Rôle des métalloprotéinases matricielles (MMPs) dans l'odontologie." Paris 5, 2005. http://www.theses.fr/2005PA05M001.

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La dégradation protéolytique des constituants de la matrice extracellulaire par les métalloprotéinases matricielles (MMPs) joue un rôle majeur dans l'odontogénèse. Après avoir identifié la présence et le profil d'expression des gélatinases (MMP-2 et MMP-9), de la MMP-20 et des TIMP-1 et -2 dans l'incisive de rat, nous avons cherché à mieux comprendre comment les MMPs et plus particulièrement les gélatinases et la MMP-20 pouvaient agir dans les processus d'organisation et de minéralisation des matrices dentaires. L'inhibition de leur activité par un inhibiteur synthétique des MMPs à large spectre, le Marimastat, dans un modèle des germes embryonnaires de souris en culture, a pertubé les mécanismes de nucléation dans la matrice dentinaire et a provoqué des pertubations sévères de la mise en place et par conséquent de la minéralisation de l'émail. Ces importantes altérations observées au niveau structural sont associées à des modifications au niveau moléculaire. En présence de Marimastat, deux des protéines majoritaires du tissu dentaire, la sialoprotéine dentinaire (DSP) et plus particulièrement l'amélogénine s'accumulent de manière anormale dans la matrice extracellulaire. Ces pertubations se traduisent par une modification de leurs différentes formes moléculaires. Ceci démontre la nécessité de la dégradation progressive de ces constituants matriciels. Le clivage de l'amélogénine par la MMP-20 a déjà été rapporté. En revanche, la dégradation protéolytique de la DSP par des protéases n'a jamais été décrite auparavant, nous avons pu montrer que la DSP mais aussi l'amélogénine sont clivées de manière rapide et totale par la MMP-2 recombinante. Par contre la MMP-9 n'a pas d'effet sur ces deux protéines dans les mêmes conditions expérimentales. La large distribution de la MMP-2 au sein des tissus dentaires, ainsi que sa capacité à dégrader certains constituants spécifiques des matrices dentaires permettent de lui attribuer un rôle majeur en association avec la MMP-20 dans l'établissement et la minéralisation de la dentine et de l'émail<br>The proteolytic degradation of the ECM components by the matrix metalloproteinases (MMPs) is thought to play a crucial role in odontogenesis. The aim of this thesis was to analyse the expression of several MMPs, namely MMP-2, MMP-9 and MMP-20, as well as of their physiological inhibitors, the TIMP-1 and TIMP-2 during tooth development and study their role in the formation and maturation of dental matrices. The two gelatinases (MMP-2 and MMP-9), enamelysin (MMP-20) and TIMP-1 and -2 have shown a developmentally regulated expression and specific localization within the developing tootth. The role of these MMPs in the processing and mineralization of the dental matrix was further studied in an organotypic culture model of developing mouse tooth germ. The inhibition of the MMPs activity in this model by a broad spectrum synthetic inhibitor, Marimastat, altered dental matrix nucleation and caused severe disruptions of enamel organisation and mineralization. These macroscopic effects was associated with significant modifications at the molecular level. MMP inhibition deregulated the molecular processing of two major dental matrix proteins, amelogenin and dental sialoprotein (DSP), coinciding with their accumulation and the loss of their normal distribution. While the cleavage of amelogenin by MMP-20 has been extensively studied, that of DSP has not been previously described. Our experiments provide evidence that MMP-2 is able to efficiently degrade DSP as well as amelogenin, while under the same conditions, MMP-9 had no effect. Based on the intense expression and large distribution of MMP-2 and its importance in the processing of the dental matrix, we suggest a major role for this enzyme, in association with MMP-20, in the maturation and mineramization of dentin and enamel
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Aspnes, Richard K., and Russell J. Yuma. "MMTS: Multi-Vehicle Metric & Telemetry System." International Foundation for Telemetering, 1988. http://hdl.handle.net/10150/615244.

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International Telemetering Conference Proceedings / October 17-20, 1988 / Riviera Hotel, Las Vegas, Nevada<br>The Multi-Vehicle Metric & Telemetry System (MMTS) is a complete range system which performs real-time tracking, command destruct, and telemetry processing functions for support of range safety and the test and evaluation of airborne vehicles. As currently configured, the MMTS consists of five hardware and software subsystems with the capability to receive, process, and display tracking data from up to ten range sensors and telemetry data from two instrumented vehicles. During a range operation, the MMTS is employed to collect, process, and display tracking and telemetry data. The instrumentation sites designated for operational support acquire tracking and telemetered data and transmit these data to the MMTS. The raw data is then identified, formatted, time tagged, recorded, processed, and routed for display to mission control and telemetry display areas. Additionally, processed tracking data is transmitted back to instrumentation sites as an aid to acquire or maintain vehicle track. The mission control area consists of a control and status console, high resolution color graphics stations, and large screen displays. As the mission controller observes mission progress on the graphics stations operational decisions can be made and invoked by activation of the appropriate console controls. Visual alarms provided my MMTS will alert mission control personnel of hazardous conditions posed by any tracked vehicle. Manual action can then be taken to activate transmission of the MMTS vehicle destruct signal. The telemetry display area consists of ten fully-functional, PC compatible computers which are switchable to either of two telemetry front end processors. Each PC can be independently set up by telemetry analysts to display data of interest. A total of thirty data pages per PC can be defined and any defined data page can be activated during a mission. A unique feature of the MMTS is that telemetry data can be combined with tracking data for use by the range safety functions.
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David, Arnaud. "Protéomique fonctionnelle des Métalloprotéases Matricielles (MMPs) dédiée à la détection des formes acitves de MMPs dans des protéomes complexes." Phd thesis, Museum national d'histoire naturelle - MNHN PARIS, 2007. http://tel.archives-ouvertes.fr/tel-00555061.

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Les Métalloprotéases matricielles (MMPs) constituent une famille des métalloprotéases à zinc capables conjointement de dégrader l'ensemble des protéines de la matrice extracellulaire. Aujourd'hui, vingt-trois MMPs humaines ont été identifiées et sont caractérisées par leur séquence en aminoacides et leur structure 3D fortement conservées. Ces enzymes sont exprimées de manière constitutive au cours des processus de remodelage tissulaire. Leur surexpression dans un certain nombre de pathologies étroitement liée au phénomène d'inflammation (arthrite, emphysème, cancer) fait des MMPs des cibles thérapeutiques de choix. Cependant, le remodelage entraînant des modifications des contacts cellulaires, les MMPs apparaissent aujourd'hui comme des protéines des voies de signalisation à part entière. Les récentes découvertes de substrats des MMPs ne faisant pas partie des constituants de la matrice extracellulaire renforcent cette vision. Dans le but d'identifier le rôle particulier et le taux d'expression protéique des MMPs dans un contexte pathologique, nous avons développé une technique de protéomique fonctionnelle dédiée à la détection des formes actives des MMPs dans des échantillons tumoraux. Cette technique repose sur le développement d'une nouvelle sonde de photoaffinité, basée sur la structure d'un puissant inhibiteur des MMPs de type phosphinique, permettant de cibler les MMPs sous forme active et de les isoler par marquage par photoaffinité. Le marquage par photoaffinité nous permet ainsi grâce à un élément radioactif incorporé à la sonde de radiomarquer les protéines ciblées. Cette sonde a montré in vitro sa capacité remarquable à modifier de manière covalente la hMMP-12 avec un rendement de 42 %, affichant une sensibilité extrême de détection (2.5 fmoles de hMMP-12). En présence de protéome complexe, la sensibilité de détection de la sonde pour la hMMP-12 est tout à fait comparable (5 fmoles) ; la hMMP-12 représente une fraction de 0.001 % de la quantité totale des protéines. Cette méthode nous a permis également d'identifier de manière indirecte les formes actives des gélatinases en comparant les extraits tumoraux traités par la sonde et les extraits tumoraux analysés en zymographie. Ces études indiquent que les niveaux d'expression des formes actives de MMPs sont très faibles (fmoles) ne permettant pas une caractérisation de celles-ci par spectrométrie de masse, ce qui constitue un véritable défi pouvant être abordé avec de nouvelles sondes incorporant une biotine. Cet exemple de protéines exprimées sous forme active en très faible abondance, implique une orientation des efforts à consentir vers le développement de nouvelles stratégies de capture.
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A, David Arnaud. "Protéomique fonctionnelle des métalloprotéases naturelles (MMPs) dédiée à la détection des formes actives de MMPs dans des protéomes complexes." Phd thesis, Museum national d'histoire naturelle - MNHN PARIS, 2007. http://tel.archives-ouvertes.fr/tel-00327187.

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Les Métalloprotéases matricielles (MMPs) constituent une famille des métalloprotéases à zinc capables conjointement de dégrader l'ensemble des protéines de la matrice extracellulaire. Aujourd'hui, vingt-trois MMPs humaines ont été identifiées et sont caractérisées par leur séquence en aminoacides et leur structure 3D fortement conservées. Ces enzymes sont exprimées de manière constitutive au cours des processus de remodelage tissulaire. Leur surexpression dans un certain nombre de pathologies étroitement liée au phénomène d'inflammation (arthrite, emphysème, cancer) fait des MMPs des cibles thérapeutiques de choix. Cependant, le remodelage entraînant des modifications des contacts cellulaires, les MMPs apparaissent aujourd'hui comme des protéines des voies de signalisation à part entière. Les récentes découvertes de substrats des MMPs ne faisant pas partie des constituants de la matrice extracellulaire renforcent cette vision. Dans le but d'identifier le rôle particulier et le taux d'expression protéique des MMPs dans un contexte pathologique, nous avons développé une technique de protéomique fonctionnelle dédiée à la détection des formes actives des MMPs dans des échantillons tumoraux. Cette technique repose sur le développement d'une nouvelle sonde de photoaffinité, basée sur la structure d'un puissant inhibiteur des MMPs de type phosphinique, permettant de cibler les MMPs sous forme active et de les isoler par marquage par photoaffinité. Le marquage par photoaffinité nous permet ainsi grâce à un élément radioactif incorporé à la sonde de radiomarquer les protéines ciblées. Cette sonde a montré in vitro sa capacité remarquable à modifier de manière covalente la hMMP-12 avec un rendement de 42 %, affichant une sensibilité extrême de détection (2.5 fmoles de hMMP-12). En présence de protéome complexe, la sensibilité de détection de la sonde pour la hMMP-12 est tout à fait comparable (5 fmoles) ; la hMMP-12 représente une fraction de 0.001 % de la quantité totale des protéines. Cette méthode nous a permis également d'identifier de manière indirecte les formes actives des gélatinases en comparant les extraits tumoraux traités par la sonde et les extraits tumoraux analysés en zymographie. Ces études indiquent que les niveaux d'expression des formes actives de MMPs sont très faibles (fmoles) ne permettant pas une caractérisation de celles-ci par spectrométrie de masse, ce qui constitue un véritable défi pouvant être abordé avec de nouvelles sondes incorporant une biotine. Cet exemple de protéines exprimées sous forme active en très faible abondance, implique une orientation des efforts à consentir vers le développement de nouvelles stratégies de capture.
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Wittig, Daniela. "Pressureless infiltrated alumina and zirconia based steel - MMCs." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek &quot;Georgius Agricola&quot, 2009. http://nbn-resolving.de/urn:nbn:de:bsz:105-712316.

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Alumina and zirconia based steel-MMCs were produced by pressureless Ti-activated melt infiltration using a high vacuum furnace. The effect of particle size and morphology on the formation of a ceramic network in-situ and MMC properties were investigated using three different alumina powders. The alumina/steel-MMCs were characterised for microstructure, Young’s modulus and strength at room temperature and elevated temperatures, and wear behaviour. Also the use of different types of steel was shown. Zirconia/steel-MMCs were produced using three different types of zirconia powder. With the use of monoclinic and partially stabilised (Ca-PSZ, Mg-PSZ) zirconia powder the effect of the monoclinic to tetragonal phase transformation on MMC microstructure and wear behaviour was shown. Further alumina preforms were successfully infiltrated in argon atmosphere at atmospheric pressure using a standard tube furnace. The infiltration in argon resulted in an increased degradation of the alumina particles. The infiltrations showed further investigations are needed for a better understanding of the mechanism of activated melt infiltration since different reactions (i.e. ceramic/metal interactions, dissolutions and evaporations) occur simultaneously during infiltration.
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Askew, John Russell. "Transient liquid phase bonding of Aluminium-based MMCs." Thesis, Brunel University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324651.

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Perrin, Carl. "Wear of aluminium alloys and alluminium-based MMCs." Thesis, University of Sheffield, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.294216.

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Books on the topic "MMVs"

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Ralph, Daniel. MMS. John Wiley & Sons, Ltd., 2004.

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Clément, Bruno, François Despatin, and Christian Gobeli. Cie: XIII avril MMVI. Abstème & Bobance, 2006.

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Trzaska, Zdzislaw. Mixed Mode Oscillations (MMOs). Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76867-6.

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Bartle, Richard A. MMOs from the Inside Out. Apress, 2016. http://dx.doi.org/10.1007/978-1-4842-1724-5.

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Bartle, Richard A. MMOs from the Outside In. Apress, 2016. http://dx.doi.org/10.1007/978-1-4842-1781-8.

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Zehetgruber, Josef. MMV: Mozart-Melodie-Verzeichnis. Doblinger, 1999.

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Liffen, David Alan. Portfolio of compositions (for MMus in composition). University of Birmingham, 1994.

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Harrison, James Patrick. Portfolio of compositions (for MMus in composition). Universityof Birmingham, 1994.

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XXVII International Congress of Genealogical and Heraldic Sciences St Andrews, 21-26 August 2006. Genealogica et Heraldica St Andrews MMVI – I. The Heraldry Society of Scotland and The Scottish Genealogy Society, 2008.

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XXVII International Congress of Genealogical and Heraldic Sciences St Andrews, 21-26 August 2006. Genealogica et Heraldica St Andrews MMVI – II. The Heraldry Society of Scotland and The Scottish Genealogy Society, 2008.

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Book chapters on the topic "MMVs"

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Fingleton, Barbara. "MMPs." In Cancer Therapeutic Targets. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4419-0717-2_21.

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Fingleton, Barbara. "MMPs." In Cancer Therapeutic Targets. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6613-0_21-3.

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Marshall, Alan, and Nazim Agoulmine. "MMNS Posters." In Management of Multimedia Networks and Services. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-540-39404-4_40.

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Baumgartlinger, Harald. "Kommunikation in MMOs." In Spielmotive und Spielertypen abseits des Mainstreams. VS Verlag für Sozialwissenschaften, 2012. http://dx.doi.org/10.1007/978-3-531-19777-7_6.

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Trzaska, Zdzislaw. "MMOs in Chemistry." In Studies in Systems, Decision and Control. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-76867-6_4.

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Sunil, B. Ratna. "Introduction to Surface MMCs." In Surface Engineering by Friction-Assisted Processes. Apple Academic Press, 2019. http://dx.doi.org/10.1201/9780429398094-7.

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Bartle, Richard A. "The Decline of MMOs." In Global Game Industries and Cultural Policy. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40760-9_15.

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Ryutova, Margarita. "Moving Magnetic Features (MMFs)." In Physics of Magnetic Flux Tubes. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45243-1_11.

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Ryutova, Margarita. "Moving Magnetic Features (MMFs)." In Physics of Magnetic Flux Tubes. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-96361-7_11.

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Nieto, Andy, Arvind Agarwal, Debrupa Lahiri, Ankita Bisht, and Srinivasa Rao Bakshi. "Mechanics of CNT-MMCs." In Carbon Nanotubes. CRC Press, 2021. http://dx.doi.org/10.1201/9780429299582-6.

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Conference papers on the topic "MMVs"

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Hibino, Stacie, and Elke A. Rundensteiner. "MMVIS." In the fourth ACM international conference. ACM Press, 1996. http://dx.doi.org/10.1145/244130.244149.

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Hibino, Stacie, and Elke A. Rundensteiner. "MMVIS." In Conference companion. ACM Press, 1996. http://dx.doi.org/10.1145/257089.257099.

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Wu, Yawen, Jingjing Wu, and Gensheng Hu. "MMFS." In ICCBDC '20: 2020 4th International Conference on Cloud and Big Data Computing. ACM, 2020. http://dx.doi.org/10.1145/3416921.3416927.

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"MMIS organizing committee." In Fourth International Conference on Web Information Systems Engineering Workshops. IEEE, 2003. http://dx.doi.org/10.1109/wisew.2003.1286778.

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Cleary, K. "Internet via MMDS." In International Broadcasting Conference (IBC). IEE, 1997. http://dx.doi.org/10.1049/cp:19971247.

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Lubbadeh, F. "MMDS/Jordanian experience." In International Broadcasting Convention - IBC '94. IEE, 1994. http://dx.doi.org/10.1049/cp:19940816.

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Chambers, Chris, Wu-chang Feng, and Wu-chi Feng. "Towards public server MMOs." In 5th ACM SIGCOMM workshop. ACM Press, 2006. http://dx.doi.org/10.1145/1230040.1230066.

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Susanto, I., P. Wood, W. Berlang, and E. Mackie. "MMV Plan." In Third EAGE CO2 Geological Storage Workshop. EAGE Publications BV, 2012. http://dx.doi.org/10.3997/2214-4609.20143807.

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Montero, Elizabeth, Maria Cristina Riff, and Daniel Basterrica. "Improving MMAS using parameter control." In 2008 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2008. http://dx.doi.org/10.1109/cec.2008.4631343.

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Polyakov, S. V., V. I. Sviridenko, V. V. Sologub, D. A. Kutepov, V. V. Zayanchukovskiy, and V. T. Gontarev. "MMDS group TV signal transmitter." In 2004 14th International Crimean Conference "Microwave and Telecommunication Technology". IEEE, 2004. http://dx.doi.org/10.1109/crmico.2004.183110.

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Reports on the topic "MMVs"

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Brodsky, J., E. Lee, A. Mabe, D. Porcincula, and X. Zhang. MMSS Indepent Review Questions and Answers. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1657685.

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Brodsky, Jason P. Mixed-Material Scintillators (MMSS Quarterly Report FY20Q2). Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1634304.

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Verma, S. K. Mobile Microwave Landing System (MMLS) User Interface. Defense Technical Information Center, 1991. http://dx.doi.org/10.21236/ada237470.

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Lynch, Conor C. How MMPs Impact Bone Responses to Metastatic Prostate Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada529376.

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Benson, J., and M. Meth. ANALYZING POWER SPECTRUM CALCULATIONS MADE ON THE BOOSTER MMPS. Office of Scientific and Technical Information (OSTI), 1991. http://dx.doi.org/10.2172/1150601.

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Marneris I. and A. G. Ruggiero. Running the AGS MMPS at 5 HZ, 24 GEV. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/1061608.

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Lynch, Conor C. How MMPs Impact Bone Responses to Metastatic Prostate Cancer. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada482544.

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Lynch, Conor C. How MMPs Impact Bone Responses to Metastatic Prostate Cancer. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada544473.

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Cross, Charles B. A Trace Specification of the MMS Security Model. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada198824.

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MARNERIS, I. SIMULATION RESULTS OF RUNNING THE AGS MMPS, BY STORING ENERGY IN CAPACITOR BANKS. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/896443.

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