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1

Małgorzata, Kulesa-Mrowiecka, Pihut Małgorzata, Słojewska Kinga, and Sułko Jerzy. "Temporomandibular Joint and Cervical Spine Mobility Assessment in the Prevention of Temporomandibular Disorders in Children with Osteogenesis Imperfecta: A Pilot Study." International Journal of Environmental Research and Public Health 18, no. 3 (January 26, 2021): 1076. http://dx.doi.org/10.3390/ijerph18031076.

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Osteogenesis imperfecta is a heterogeneous group of hereditary disorders of connective tissue diseases characterized by increased bone fragility, low growth, sometimes accompanied by abnormalities within the dentine, blue sclera, and partial or total hearing impairment. The changes may affect all joints, including the cervical spine and temporomandibular joints in the future, resulting in pain. The aim of the present study was to assess whether there is a relationship between the active range of motion of the cervical spine and the mobility of temporomandibular joints due to differential diagnosis in children with osteogenesis imperfecta, and to present a prevention algorithm for temporomandibular disorders. The study involved a group of 34 children with osteogenesis imperfecta, and the control group included 23 children (age 9.1 ± 3.8 years). Data were collected through an interview based on the author’s questionnaire, and the physical examination consisted in measuring the mobility of the cervical spine using an inclinometer (Cervical Range of Motion Instrument), the Helkimo scale, and linear measurements. In children with congenital bone fragility, there were acoustic symptoms from the temporomandibular joints more often than in healthy children. A correlation was found between the mobility of the cervical spine and temporomandibular joints in the study group. In the case of detecting irregularities in the temporomandibular joints, children were ordered to perform jaw-tongue coordination exercises.
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Kryukov, E. R., Yu P. Potekhina, L. V. Vdovina, and A. A. Kournikova. "Age-related and sexual features of the mobility of the temporomandibular joints." Russian Osteopathic Journal, no. 1 (March 24, 2022): 69–77. http://dx.doi.org/10.32885/2220-0975-2022-1-69-77.

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Introduction. Pathology of the temporomandibular joints (TMJ) is widespread even among young people, and the frequency of its occurrence increases with the age of patients. In this case, there is violated one of the main characteristics of the joints — mobility, which is measured by the mouth opening width (MOW). There is not enough information in the literature on the age and sex characteristics of the TMJ mobility in individuals without pathology of this joint.The aim of the study is to research the mobility of the TMJ in different age groups in men and women without pathology of this joint.Materials and methods. There were examined 714 patients who applied for dental care, aged 20 to 79 years (504 women and 210 men), without pathology of the TMJ. The range of motion in the TMJ was measured using a caliper with thin lips during the opening of the mouth in a neutral head position. The subjects were divided into age groups: 20–29, 30–39, 40–49, 50–59, 60–69 and 70–79 years old.Results. It was found that the most common MOW value was 4,9 cm (range from 4,5 to 5,2 cm). A distribution of relative frequencies corresponding to the normal Gaussian distribution was observed for this indicator. The mobility of the TMJ changed little with age. Analysis of the distribution of temporomandibular joint mobility by age groups of patients with a step of 10 years showed the similarity of the average MOW values in all groups of subjects, except for the group of 20–29 years. Their average values (4,75 cm) were lower than those of the other groups (4,9 cm, p<0,05). It was found that men have a higher mobility of the TMJ compared to women in all age groups (on average by 0,28 cm, p<0,05).Conclusion. Mouth opening widths of 4,6 to 5,2 cm (average 4,9 cm) can be considered as normal. TMJ mobility is not related to age. Consequently, a decrease in the mobility of the TMJ in persons of older age groups cannot be considered as normal age-related changes. TMJ mobility depends on sex. Men have higher TMJ mobility than women in all age groups. Thus, the TMJ differ from other joints not only in their complexity (two joints always work together), but also in age and sex patterns of mobility.
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Dijkstra, Pieter U., Lambert G. M. de Bont, Leo Th van der Weele, and Geert Boering. "The Relationship Between Temporomandibular Joint Mobility and Peripheral Joint Mobility Reconsidered." CRANIO® 12, no. 3 (July 1994): 149–55. http://dx.doi.org/10.1080/08869634.1994.11678011.

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4

Araujo, Juliane Piragine, Marcelo Eduardo Pereira Dutra, and Karina Cecilia Panelli Santos. "Association between disc displacement without reduction and temporomandibular joint derangement observed on magnetic resonance imaging." Clinical and Laboratorial Research in Dentistry 21, no. 4 (December 31, 2015): 211. http://dx.doi.org/10.11606/issn.2357-8041.clrd.2015.127551.

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This study aimed to assess possible associations between the following factors: articular disc anatomy and position; articular eminence and condyle morphology; presence of joint effusion; condyle mobility; and lateral pterygoid muscle insertion pattern. Magnetic resonance images of 33 joints of symptomatic patients were assessed. The articular disc was classified as normal, elongated, or folded; displacement was classified as normal, lateral, or medial; the condyle was classified as rounded, convex, flattened, or angulated; the articular eminence was classified as box, sigmoid, flattened, or deformed; condyle mobility was classified as normal, hypomobile, or hypermobile; and the lateral pterygoid muscle insertion pattern was classified as Type I, Type II, or Type III. The most frequent forms of articular disc, articular eminence, and condyle were folded, flattened, and flattened, respectively. There can be a relationship connecting TMJ mobility with a normal disc form (100%); TMJ hypomobility with a folded disc form (48%); and TMJ hypermobility with an elongated disc form (100%). Magnetic resonance imaging allowed the clear observation of articular structures, and no association was found between insertion pattern and sideways disc position, disc form, and condyle form. All cases with joint effusion were related to hypomobility (100%).
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Savioli, Cynthia, Clovis A. A. Silva, H. Ching Lin, Lucia M. M. A. Campos, Eliane F. B. G. Prado, and José Tadeu T. Siqueira. "Dental and facial characteristics of patients with juvenile idiopathic arthritis." Revista do Hospital das Clínicas 59, no. 3 (2004): 93–98. http://dx.doi.org/10.1590/s0041-87812004000300001.

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OBJECTIVE: It has been shown that the temporomandibular joint is frequently affected by juvenile idiopathic arthritis, and this degenerative disease, which may occur during facial growth, results in severe mandibular dysfunction. However, there are no studies that correlate oral health (tooth decay and gingival diseases) and temporomandibular joint dysfunction in patients with juvenile idiopathic arthritis. The aim of this study is to evaluate the oral and facial characteristics of the patients with juvenile idiopathic arthritis treated in a large teaching hospital. METHOD: Thirty-six patients with juvenile idiopathic arthritis (26 female and 10 male) underwent a systematic clinical evaluation of their dental, oral, and facial structures (DMFT index, plaque and gingival bleeding index, dental relationship, facial profile, and Helkimo's index). The control group was composed of 13 healthy children. RESULTS: The mean age of the patients with juvenile idiopathic arthritis was 10.8 years; convex facial profile was present in 12 juvenile idiopathic arthritis patients, and class II molar relation was present in 12 (P = .032). The indexes of plaque and gingival bleeding were significant in juvenile idiopathic arthritis patients with a higher number of superior limbs joints involved (P = .055). Anterior open bite (5) and temporomandibular joint noise (8) were present in the juvenile idiopathic arthritis group. Of the group in this sample, 94% (P = .017) had temporomandibular joint dysfunction, 80% had decreased mandibular opening (P = 0.0002), and mandibular mobility was severely impaired in 33% (P = .015). CONCLUSION: This study confirms that patients with juvenile idiopathic arthritis a) have a high incidence of mandibular dysfunction that can be attributed to the direct effect of the disease in the temporomandibular joint and b) have a higher incidence of gingival disease that can be considered a secondary effect of juvenile idiopathic arthritis on oral health.
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Costa, André L., Lidiane S. Campos, Marcondes C. França Jr., and Anelyssa D'Abreu. "Temporomandibular disorders in patients with craniocervical dystonia." Arquivos de Neuro-Psiquiatria 69, no. 6 (December 2011): 896–99. http://dx.doi.org/10.1590/s0004-282x2011000700009.

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Temporomandibular disorders are a set of musculoskeletal dysfunctions within the masticatory system, with multiple etiologies. OBJECTIVE: Since craniocervical dystonia can involve the same neuromuscular structure as the temporomandibular joint, we sought to assess the correlation between temporomandibular disorders and craniocervical dystonia. METHOD: We applied the Research Diagnostic Criteria for Temporomandibular Disorders to 42 patients with craniocervical dystonia, in order to identify orofacial pain and temporomandibular characteristics on the day of botulinum toxin injection. RESULTS: Twenty-two patients (52.3%) reported temporomandibular joint pain; 24 (57.1%), joint sounds; 20 (47.6%), masticatory muscle pain; and 21 (50%), diminished jaw mobility. The patients with oromandibular dystonia presented temporomandibular disorders more frequently than did patients with other types of craniocervical dystonia (p<0.001). CONCLUSION: Temporomandibular disorders occur frequently in patients with oromandibular dystonia. Further studies should address the proper treatment of temporomandibular disorders associated with dystonia.
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Dickerson, Shantil M., Jarod M. Weaver, Ashley N. Boyson, Jared A. Thacker, Andrew A. Junak, Pamela D. Ritzline, and Megan B. Donaldson. "The effectiveness of exercise therapy for temporomandibular dysfunction: a systematic review and meta-analysis." Clinical Rehabilitation 31, no. 8 (October 3, 2016): 1039–48. http://dx.doi.org/10.1177/0269215516672275.

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Objective: To investigate the effectiveness of exercise therapy on pain, function, and mobility outcomes in patients with temporomandibular joint dysfunction. Study design: Systematic review with meta-analysis. Methods: A systematic review and meta-analysis undertaken following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies that met the inclusion criteria: (1) randomized controlled trials; (2) a population with the diagnosis of temporomandibular joint dysfunction; and (3) interventions that included exercise therapy were considered for review. When studies demonstrated homogeneity on outcome measures, the mean differences or standardized mean differences with 95% confidence interval were calculated and pooled in a meta-analysis for pooled synthesis. Results: Six articles with a total of 419 participants were included in the review and only four studies were included in the meta-analysis. Mobility and mixed exercise therapy approaches appear to be the most common exercise approaches utilized for management of temporomandibular joint dysfunction. Exercise therapy and the associated dosage provide moderate short-term and varying long-term benefits in reduction of pain and improvement of range of motion of the in patients with temporomandibular joint dysfunction. Conclusion: Included studies suggest a mobility or a mixed approach to exercise therapies have impact on reducing pain, significant impact for increasing range of motion, but lack a significant impact for functional improvement. Level of evidence: Therapy, level 1a-.
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Velisavljev-Filipovic, Gordana. "Arthrogryposis multiplex congenita - a rare congenital stiff joints syndrome." Medical review 59, no. 7-8 (2006): 375–79. http://dx.doi.org/10.2298/mpns0608375v.

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Introduction: Arthrogryposis multiplex congenita is not a disease but a term describing multiple congenital contractures. Etiological factors include neurological and primary myogenic diseases. This rare syndrome is present at birth and is characterized by reduced mobility of many joints. The contractures involve two or more joints with ankylosis. The accompanying musculature is hypoplastic, but multiple pterygia are also present. Arthrogryposis multiplex congenita is a heterogeneous group of disorders with the incidence rate of 6.2/100000 liveborn infants. The true incidence cannot be established, because many cases result in spontaneous miscarriages or stillbirth. More than 90% of cases are associated with birth defects. The cause of this syndrome is unknown. Many forms are not hereditary, though there are hereditary forms as well. Case report. This paper presents a case with arthrogryposis multiplex congenita. The pregnancy was not controlled regularly. During the pregnancy, oligohydramnion was detected. Due to contractures, labor ended is cesarean section. The child was born in the 34th week of gestation. Flexion and extension joint contractures were observed. Active and passive mobility of the afflicted joints was reduced. There was a limited motor function in the shoulder, elbow and wrist joints with a slight internal rotation of the shoulder joint and lower arm joints during pronation. The hips were subluxated; the feet were in equinovarus position and the fingers in ulnar deviation with partial syndactyly of the 4th and 5th fingers on the left hand. The infant had abnormal dermatoglyphics. The neck was short, and the 2nd and 3rd cervical vertebrae were fused. There was also a slight left-sided thoracic scoliosis. Trismus was present due to the existing ankylosis of the temporomandibular joint. The karyotype was normal. The serum creatinine phosphokinase was slightly elevated. The electromyographic picture indicate non-specific signs of myopathy. Discussion and conclusion. This is a case report of a "stiff joint syndrome". Due to the fact that data from the family history were unavailable, we could not establish the type of syndrome. However, heredity, growth and development at later age, as well as IQ, might significantly help in definite differentiation of this syndrome. In pregnancy, oligohydramnion should indicate more detailed ultrasonographic examination, as ankylosed joints can be detected in utero. .
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9

DIJKSTRA, P. U., L. G. M. BONT, B. STEGENGA, and G. BOERING. "Temporomandibular joint mobility assessment: a comparison between four methods." Journal of Oral Rehabilitation 22, no. 6 (June 1995): 439–44. http://dx.doi.org/10.1111/j.1365-2842.1995.tb00798.x.

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Sahin, Sevtap Hekimoglu, Ali Yılmaz, Isıl Gunday, Murat Kargı, Necdet Sut, Oguz Taskınalp, and Enis Ulucam. "Using temporomandibular joint mobility to predict difficult tracheal intubation." Journal of Anesthesia 25, no. 3 (March 31, 2011): 457–61. http://dx.doi.org/10.1007/s00540-011-1126-3.

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Sonnesen, Liselotte, Arne Petersson, Mie Wiese, Karl Erik Jensen, Palle Svanholt, and Merete Bakke. "Osseous osteoarthritic-like changes and joint mobility of the temporomandibular joints and upper cervical spine: is there a relation?" Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 123, no. 2 (February 2017): 273–79. http://dx.doi.org/10.1016/j.oooo.2016.10.026.

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12

Veras, Nirlley Karcia da Silva, Antônia Mykaele Cordeiro Brandão, Francisco Lázaro Arruda, Fernanda Mello da Silva Sousa, and Guilherme Pertinni de Morais Gouveia. "The effect of low-level laser therapy on functional improvements in the temporomandibular joints: randomized clinical trial." Research, Society and Development 10, no. 4 (April 18, 2021): e46110414387. http://dx.doi.org/10.33448/rsd-v10i4.14387.

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Introduction: Temporomandibular disorders (TMD) - recognized as the most common chronic orofacial pain condition - significantly impacts individuals’ quality of life and social coexistence. Therefore, this study aimed to analyze the effects of low-level laser therapy (LLLT) on functional improvements in the temporomandibular joints (TMJ). Method: The research was carried out at the Universidade Federal do Piauí on 32 young adults with signs and symptoms of TMD, who were divided into the intervention group (IG) and the control group (CG). The IG was administered the LLLT application directly on the TMJ. While both groups were subjected to the same procedures, for the CG, the laser device was turned off. Results: The mean age of the participants was 21.87 ± 2.4 years, with a predominance of females (87.5%) over males (12.5%). Homogeneity was observed between the CG and IG concerning the presence of pain from palpation. The decrease in the pain of the musculature was relevant, with emphasis on the IG, which used LLLT. Moreover, there was an increase in participants, who rated on the pain scale their pain as “0” (no pain), and presented increased measures of joint mobility of the mandible and cervical spine, with relief of the painful symptoms, by breaking the pain-spasm-pain cycle. Conclusion: LLLT promotes a significant reduction of pain from palpation, improves the range of motion, and generates immediate and long-lasting benefits.
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BOCHIS, Calin, Liviu LAZAR, Carmen NISTOR-CSEPPENTO, Felicia CIOARA, and Nicoleta PASCALAU. "Prevalence of clinical manifestations of temporomandibular osteoarthrosis." Balneo Research Journal 10, Vol.10, No.3 (September 3, 2019): 317–20. http://dx.doi.org/10.12680/balneo.2019.275.

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Introduction. The two compartments, disco-temporal and condilo-discal, which make up the temporo-mandibular joint, fulfill the functions of the stomatognathic system, namely: phonation, mastication and swallowing. The temporo-mandibular degenerative pathology is one of the 5 clinical entities given by the American Academy of Orofacial Pain in 1993. The symptoms are varied, dominated by pain, impaired joint mobility, cracks, sensation of muscle fatigue in the masseter and temporal muscles. Most cases benefit from conservative treatment, consisting of anti-allergic and anti-inflammatory medication, specific orthodontic treatment, electrotherapy (TENS, ultrasound, magnetodiaflux, laser), kinesiotherapy. 2-5% of patients require surgery. Material and method. We performed a retrospective study, over a 9-year period (January 2010-March 2019), in which we included 503 patients who went to the Timisoara Oro-Maxillofacial Surgery Clinic, with a definite diagnosis of temporomandibular algodisfunctional syndrome, of different etiologies, between the ages of 6 and 85 years. We evaluated the etiology of temporomandibular algodisfunctional syndrome, the prevalence of clinical manifestations in temporomandibular osteoarthritis and their evolution after 10 days of conservative treatment. Results and discussions. Pain is present in 100% of cases, the values obtained in these patients with temporomandibular osteoarthritis are between 10 and 40mm. Cracks are present in women in the percentage of 40.8% and 37.9% in men; mobility limitation is found in women in 11% of cases, and in men in 15% of cases. Conclusions. The existence of a protocol for the diagnosis of TM osteoarthritis is essential to establish the treatment plan and prognosis of the disease. The pain from osteoarthritis TM is low intensity, present in all patients; cracks and limiting mobility are present in comparable proportions, regardless of gender. The response to treatment was optimal at 21 days of treatment.
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Sikora, Maciej, Barbara Czerwińska-Niezabitowska, Maciej Adam Chęciński, Marcin Sielski, and Dariusz Chlubek. "Short-Term Effects of Intra-Articular Hyaluronic Acid Administration in Patients with Temporomandibular Joint Disorders." Journal of Clinical Medicine 9, no. 6 (June 5, 2020): 1749. http://dx.doi.org/10.3390/jcm9061749.

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The study described in this paper was conducted to assess the short-term outcomes of intra-articular administration of hyaluronic acid in patients with symptoms of temporomandibular joint disorders. A group of 40 patients suffering from temporomandibular joint disorders underwent a series of hyaluronic acid intra-articular injections. Questionnaires and clinical examinations were conducted to assess stress exposure of the subjects and to evaluate short-term treatment outcomes, i.e., reducing joint and muscle pain and increasing the mobility of the mandible. A weak positive correlation between stress exposure and pain was observed. As a result of treatment, 61% of subjects revealed a total reduction of muscle pain, while joint pain completely resolved in 88% of patients. Mandibular mobility increased by 11%, 31%, 9%, and 11% regarding opening, protrusive, and lateral right and left movements, respectively. The study confirms the short-term effectiveness of intra-articular administration of hyaluronic acid on reducing joint and muscle pain in patients with articular disc displacement. The treatment positively affected the mobility of the mandible in all directions. The verification of late treatment effects of hyaluronic acid viscosupplementation requires the continuation of the research.
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Kulesa-Mrowiecka, Małgorzata, Joanna Piech, and Tadeusz S. Gaździk. "The Effectiveness of Physical Therapy in Patients with Generalized Joint Hypermobility and Concurrent Temporomandibular Disorders—A Cross-Sectional Study." Journal of Clinical Medicine 10, no. 17 (August 25, 2021): 3808. http://dx.doi.org/10.3390/jcm10173808.

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Temporomandibular disorders (TMD) consist of a group of symptoms such as: pain of temporomandibular joints, masticatory muscles or surrounding tissues, dysfunctions of TMJs’ mobility, and crepitation. The Hypermobility Joint Syndrome (HJS) manifests in the flaccidity of joint structures, an increase in the range of joint motion, and occurs more often in the young and women. The aim of this study was to present the occurrence of HJS among patients with myogenic TMD and disc displacement with reduction. The secondary goal was to assess the effectiveness of physiotherapy directed to TMD with coexisting HJS. The study involved 322 patients with symptoms of TMD. HJS was diagnosed using the Beighton Scale, which confirmed its occurrence in 26 cases. 79 subjects (7 males and 72 females; mean age, 33.9 ± 10.4 years) were selected and divided into two groups: HJS + TMD (n = 26; 2 males and 24 females; mean age, 27.1 ± 9.4 years) and TMD (n = 53; 5 males and 48 females; mean age, 37.4 ± 9.2 years). These patients completed 3-week physiotherapy management. Before and after physiotherapy, the myofascial pain severity on Numeric Pain Rating Scale, linear measurement of maximum mouth opening, and opening pattern, were assessed. To demonstrate differences between the results, the level of significance for statistical analysis was set at α = 0.05. A statistically significant improvement was obtained in decreasing myofascial pain in both groups. Coordination of mandibular movements was achieved in both groups. Generalized joint hypermobility occurred among patients with TMD. Physiotherapy directed to TMD was effective in reducing myofascial pain and restoring TMJ’s coordination also in patients with HJS.
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Urban, Magdalena, Kladia Suligowska, Anna Wytrykowska, Maria Prośba-Mackiewicz, Tomasz Zdrojewski, and Magdalena Wrotkowska. "Parafunctions, signs and symptoms of temporomandibular disorders (TMD) among adolescents 14 to 15 years of age." Journal of Stomatology 69, no. 6 (December 31, 2016): 712–24. http://dx.doi.org/10.5604/00114553.1230591.

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Introduction. Temporomandibular Joint Disorders (TMD) increasingly affect not only adults but also adolescents. Parafunctions are cited as the most common cause of TMD. Aim of the study. To determine the prevalence of oral parafunctions, signs and symptoms of TMD among adolescents. Methods. The study was performed as a part of an early detection of risk factors for civilization diseases program – SOPKARD1 in 96 children aged 14-15 years. Each participant filled in a questionnaire regarding their oral habits and symptoms of TMD and underwent physical examination of the muscles and temporomadibular joints. The analysis of the mandible mobility models was also made. Results. Leaning one’s chin on the hand (73.68%), lip biting (58.33%) and intensive gum chewing (51.04%) were the most common habits among the study group. Persistence of an infantile swallow pattern was observed in over one-fifth of patients (20.83%). The most common signs were teeth impressions on tongue and cheeks (53.13%), increased muscle tone (57.29%) and dysfunctions in mandibular mobility (53.13%). Most subjects (92.71%) manifested at least one sign or symptom, whereas 46.88% two or three. A statistically significant association was found between chewing gum and muscle response, as well as infantile swallow pattern and open bite and muscle response. Conclusions. Most adolescent aged 14-15 were subject to some parafunctional habits. There is a requirement to introduce an educational program in schools in order to present the destructive consequences of parafunctions on the stomatognathic system health and the possibility of prevention or treatment.
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Brahem, M., A. Ben Salem, H. Hachfi, R. Sarraj, S. Abedallatif, R. Tekaya, C. Baccouche, and Y. Mohamed. "AB0192 EVALUATION OF TEMPOROMANDIBULAR JOINT INVOLVEMENT IN PATIENTS WITH RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1120.1–1120. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4194.

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Background:Rheumatoid Arthritis (RA) is the most common chronic inflammatory disease usually involves peripheral joints with a symmetric distribution. The temporomandibular joint (TMJ) is seldom joint to be affected first in the disease course.Objectives:The Aim of our study is to describe and to assess the prevalence of temporomandibular joint (TMJ)disorders in patients with Rheumatoid arthritis (RA).Methods:A cross sectional study including RA patients, which consulted or were hospitalized in Rheumatology department in Taher Sfar Hospital of Mahdia Tunisia, during a period of 10 months. The diagnosis of the RA was secured by the ACR/EULAR 2010, Rheumatoid Arthritis Classification Criteria. The clinical TMJ examination was performed by a trained dentist in the same hospital. We assessed TMJ pain with VAS (visual analog scale) which varies from 0 to 10. The following key parameters were evaluated: The pain on the TMJs by bilateral palpation; The TMJ sounds (clicking or crepitus) during opening closing of the mandible; dysfunction and movement alterations. Clinical and sociodemographic parameters were also determined.Results:Our study included 51 patients with an average age of 51.11 years ±12.4 [21-74years]. 50patients (92.6%of cases) were women and 8 patients (14.8%) were diabetic. Only one patient was a smoker. The mean duration of RA was 10.7 years 7.7± [10months-35years]. Rheumatoid factor (RF) was positive in 25 Patients (46.3%of cases). Anti-citrullinated peptide antibody (ACPA) was positive in 32 patients (59.3 %).41patients (75.4%) had radiological impairments and 28 (51.9%) had specific deformations of RA. The average disease activity score (DAS28-VS) and (DAS28-CRP) were respectively 4.1±1.5 [1.4-7.3] and 3.4±1.5 [1.24-6.71]. TMJ pain was present in 29 patients (56.9 %) which67.7% appeared before ten years. 5 patients (16.7%) had VAS more than 7 that mean a severe pain. TMJ involvement was bilateral in 64.3% and unilateral in 35.7 %. Functional difficulties were detected in 22 patients (44.9 %). TMJ examination had also revealed a limitation of mouth opening in 11 patients (21.2 %), a movement alteration in 13 patients (27.79 %), a clicking in joint mobility in 13 patients (81.3 %) and joint crepitus in 1 patient (6.3%). Disease duration was associated with TMJ pain(p=0.05) and mobility alterations (p=0.04). Functional difficulties of the TMJ were correlated with DAS28 (p=0.02). In our study we found also that duration of corticosteroid therapy had in impact on TMJ pain (p=0.01), functional difficulties (p=0.01) and movements alterations (p=0.004).Conclusion:TMJ is very rare to be affected in the early phase of the disease, thus patient may develop signs and symptoms in the course of time. Our study showed the frequency of TMJ disorders and the most important factors were the activity of RA and the duration of the disease course.Disclosure of Interests:None declared
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Rab, Md Abdur, Golam Mohiuddin Chowdhury, Abdullah Al Mehedi, Quazi Sindhi, Mohammad Iqbal Kabir, and Shaila Sharmin. "Management of Temporomandibular Joint Disorders by Arthroscopic Lavage." Journal of Armed Forces Medical College, Bangladesh 12, no. 1 (January 24, 2016): 88–93. http://dx.doi.org/10.3329/jafmc.v12i1.39976.

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Introduction: Temporomandibular joint disorders (TMDs) are among the most common disorders in the maxillofacial region which usually present with joint pain, decreased jaw mobility, joint clicking, headache, tinnitus, neck pain etc. There are different modalities of treatment used for the TMDs. These include some conservative and surgical procedures. The main aim is to improve the jaw function and reduction of joint pain. Arthroscopy is a modern diagnostic and effective therapeutic procedure for the TMDs. Objective: To assess the outcome of arthroscopic lavage of Temporomandibular Joint (TMJ) in terms of improvement of jaw function and joint pain in patients suffering from TMDs. Materials and Methods: This prospective study was carried out at the department of Oral and Maxillofacial Surgery, Military Dental Centre, Combined Military Hospital of Dhaka Cantonment from 01 October 2014 to 31 March 2016. Patients were selected consecutively having TMDs and unresponsive to conservative nonsurgical therapy. Total thirty patients of TMDs were selected for study and all the patients were treated with arthroscopic lavage. Objective data were collected including, inter incisal opening, lateral excursion, deviation on opening, tenderness on palpation. A questionnaire in the form of visual analogue scale relating to pain, joint clicking and Jaw mobility were completed by each patient at 1 week,1 month and 6 months post operatively. Results: Among thirty patients, 10 patients were male and 20 patients were female. Mean age of the patient was 42.6±5.79 years. Maximum patients were in the age group of 41-45 years. There was statistically significant improvement in maximum incisal opening and pain score. There was also reduction in Joint clicking and tenderness in maximum patients. Conclusion: The findings of the present study suggested potential utility of arthroscopic lavage in the management of TMDs. Journal of Armed Forces Medical College Bangladesh Vol.12(1) 2016: 88-93
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Chęciński, Maciej, Maciej Sikora, Kamila Chęcińska, Zuzanna Nowak, and Dariusz Chlubek. "The Administration of Hyaluronic Acid into the Temporomandibular Joints’ Cavities Increases the Mandible’s Mobility: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 11, no. 7 (March 29, 2022): 1901. http://dx.doi.org/10.3390/jcm11071901.

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Objectives: The purpose of this systematic review with meta-analysis is to identify clinical studies concerning the impact of intra-articular administration of hyaluronic acid (HA) on mandibular mobility and to make an attempt at determining the efficacy of HA in this indication. Methods: The review included primary studies involving groups of at least 10 patients who were diagnosed with pain in the temporomandibular joint and who were injected with hyaluronic acid as the only intervention. The outcomes pursued were changes in mandibular mobility and pain intensity. Four databases of medical articles were searched, including PubMed and BASE. The risk of bias was assessed using the Cochrane methodology tools. The therapy‘s efficacy was calculated in the domains of mandibular abduction, protrusive movement, lateral mobility, and pain relief. For these values, the regression and correlation with variables characterizing the interventions were analyzed. Results: In total, 16 reports on 20 study groups with a total of 1007 patients qualified for the review. The mean effectiveness in the domain of mandibular abduction over the 6-month follow-up period was 122% of the initial value, and the linear regression model can be expressed as 0.5x + 36. The level of pain in the same time frame decreased to an average of 29%. The severity of pain 6 months after the beginning of treatment positively correlates with the number of injections per joint (0.63), the total amount of drug administered in milliliters (0.62), and the volume of drug administered monthly per joint (0.50). Limitations: In some studies, the patient groups were heterogeneous in terms of diagnosis. The studies varied depending on the joint into which the HA was administered. The synthesized studies differed with regard to the method of measuring the mandible abduction amplitude. Conclusions: The increase in the amplitude of mandibular abduction was expressed as the quotient of the mean values during the observation periods, and the initial value was achieved in all study groups, and in the linear regression model, it was 0.5 mm on average per month. Multiple administrations of the drug may reduce the analgesic effectiveness of the treatment.
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Sencimen, Metin, Altan Varol, Baris Baykal, Hasan Ayberk Altug, Necdet Dogan, Sermet Sahin, Kemal Murat Okcu, and Bulent Yalcin. "Histological Characteristics of Ligaments between Middle Ear and Temporomandibular Joint." European Journal of Dentistry 03, no. 04 (October 2009): 280–84. http://dx.doi.org/10.1055/s-0039-1697445.

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ABSTRACTObjectives: To examine histological aspects of the ligaments between the middle ear and temporomandibular joint and suppose a theoretical role of their structural characteristics on mobility of mallear ossicle.Methods: The ligaments were obtained by microdissection of middle cranial fossa on both sites of 15 cadavers fixed in formalin solution and were sectioned longitudinally (7-10 µm thickness). The sections were stained with Verhoff’s Van Gieson’s stain (VVG) for demonstration of elastic fibers and visualized at X2.5 and X10 magnifications under light microscopy.Results: Anterior mallear ligament (AML) and sphenomandibular ligaments (SML) were consisted of collagen fibres in analyzed specimens. The discomallear ligament (DML) was constituted of rich collagenous fibres. One specimen of DML harvested between petrotympanic fissure and retrodiscal-capsular intersection site contained elastic fibers dispersed in cotton-bowl appearance between collagen fibers. In the light of functional tests performed in previous studies, it could be extrapolated that presence of elastic fibers in the DML may prevent excessive forces conducted to mallear head by elongation of elastic fibers.Conclusions: Collagenous fibres have no ability to stretch along their axis which may lack compensatory mechanism to prevent mallear head mobility. (Eur J Dent 2009;3:280-284)
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Martins, Wilson Denis. "Report of Ankylosis of the Temporomandibular Joint: Treatment with a Temporalis Muscle Flap and Augmentation Genioplasty." Journal of Contemporary Dental Practice 7, no. 1 (2006): 125–33. http://dx.doi.org/10.5005/jcdp-7-1-125.

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Abstract A case of true bilateral ankylosis of the temporomandibular joint (TMJ) is presented. A 19-year-old male patient had a life-threatening ear infection at the age of ten resulting in a progressive restriction of his mouth opening. He presented with almost complete lack of mobility of the mandible. Surgical treatment was a resection of the ankylotic mass, interpositional temporalis composite muscle flaps, and early mobilization and aggressive physiotherapy. The functional results of the interpositional arthroplasty were excellent. After a twoyear follow up, an augmentation genioplasty was performed in order to improve facial aesthetics. Citation Martins WD. Report of Ankylosis of the Temporomandibular Joint: Treatment with a Temporalis Muscle Flap and Augmentation Genioplasty. J Contemp Dent Pract 2006 February;(7)1:125-133.
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Melnyk, V. L., V. K. Shevchenko, and Yu I. Sylenko. "POSITION OF THE TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME AMONG FACIAL PAIN SYNDROMES." Ukrainian Dental Almanac, no. 1 (March 21, 2018): 79–82. http://dx.doi.org/10.31718/2409-0255.1.2018.19.

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At the present time, the actual problem of dentistry is the study of the issues of the syndrome of pain dysfunction (SPD) of the temporomandibular joint (TMJ), which is found in 14-20% of teenagers and significantly increases with age (Siemkin V.A, Rabukhina N.A., 2000 ; Khavatova VA, 2005). The pathology of TMJ dysfunction was detected in 80% of the examined patients (Bezrukov V.M, 2002). Separately allocated dysfunction of TMJ in dysplastic-dependent form of joint pathology, thereby emphasizing that dysfunction is a characteristic manifestation of dysplasia of connective tissue in the maxillofacial area (Statovskaia Ye.Ye, 2005; Kozlov D.L., Viazmin A.Y., 2007). According to observations of A.I Mirza, I.V. Mikheieva, V.M. Novikov and according to our data, in more than 90% of people, pathological phenomena in the area of the temporomandibular joint have nothing to do with the inflammatory processes of this combination. At the same time, various dysfunctions and pain spasm of separate areas of chewing muscles occupy the main place. The aim of the work was to analyze the causes and clinical symptoms of patients with SPD. In this regard, as it turned out from the anamnesis, many patients had been undergoing inappropriate treatment for a long time. The cavity of the temporomandibular joint was repeatedly injected emulsion hydrocortisone acetate, antibiotics and other medications, which do not work in case of SPD of the temporomandibular joint. In some cases, after such therapy, dysfunction of the mandible occurred, leading to an even greater disruption of the joint function and increased pain. A number of patients with SPD of the temporomandibular joint due to a false diagnosis for a long time received treatment for neuralgia of the trigeminal nerve by drugs, Novocain blockade or alcoholization of sensitive branches of the trigeminal nerve. These patients often had neuritis, which greatly worsened the patient’s condition and the prognosis of the disease. The clinical picture of the SPD of the temporomandibular joint and a number of such diseases (syndromes of Slider, Sikara, etc.) is often so obscure and confusing that a large clinical experience is needed to evaluate individual symptoms. In addition, it should be noted that dysfunction of the mandible occurs with lesions of any part of the temporomandibular complex. Thus, limitation of the mobility of the mandible usually develops with arthritis of the temporomandibular joint, abscesses and phlegmons of the parotideomasseterica, temporal regions, pterygomandibulare, parapharingenal space, jaw-tongue groove and osteomyelitis of the branches of the mandible. Diagnostic difficulties often increase due to the fact that it is not always possible to find out the atypical etiological origin of the SPD of the temporomandibular joint. Against the background of the listed objective adverse factors, the presence of diagnostic errors largely contributes to insufficient knowledge of dentists who have clinical questions and questions on treatment of the SPD TMJ due to the difficulty in differential diagnosis, which is not fully covered in textbooks on dentistry. Control of correctness of the established diagnosis is the blockade of the motor branches of the trigeminal nerve subcutaneously using the Yehorov's method, which results in the removal of muscle spasm, stops pain and improves the mobility of the mandible. Conducting additional paraclinical examination methods such as dynamic MRT, 3-D MRT, CT and electromyography should be done.
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MELO, Daniela Pita de, Luciana Soares de Andrade Freitas OLIVEIRA, Ana Clara Alves de CARVALHO, Anne Caroline Costa OENNING, Amanda Katarinny Goes GONZAGA, and Paulo Sérgio Flores CAMPOS. "Temporomandibular joint disk adhesion: evidence from magnetic resonance images." RGO - Revista Gaúcha de Odontologia 62, no. 2 (June 2014): 169–72. http://dx.doi.org/10.1590/1981-86372014000200000112753.

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This case report has the aim to present an adhesion of the temporomadibular disc to the articular eminence, diagnosed on magnetic resonance imaging images. A 37-year-old female patient with TMJ (temporomandibular joint) disk adhesion on the left side and complaining of bilateral otalgia over the last 2 years is reported in the present article. The patient did not complain of articular pain or clicking, or any other noises of any nature. Clinical observation showed that the patient had restricted jaw opening, with mandibular deviation the left side without correction during mandibular movement. Our diagnostic impression was of partial anterior disk displacement with reduction of the right side disc; and partial anterior disk displacement with reduction and disc disk adhesion with hypo-mobility of the condyle, on the left temporomandibular joint. The peculiarity of this reported case is the fact that besides the bilateral partial anterior disc displacement, there was also found an adhesion of the disc on the left side. In conclusion, the magnetic resonance imaging exam of the temporomandibular joint can be considered an exam of choice for the evaluation of disc positioning and its morphological alterations.
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Johansson, Ann-Sofi, and Annika Isberg. "The anterosuperior insertion of the temporomandibular joint capsule and condylar mobility in joints with and without internal derangement: A double-contrast arthrotomographic investigation." Journal of Oral and Maxillofacial Surgery 49, no. 11 (November 1991): 1142–48. http://dx.doi.org/10.1016/0278-2391(91)90404-a.

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Olkhovik, Alina, Oleksandr Yurchenko, Olha Yezhova, Vladyslav Smiianov, Inna Mordvinova, Alla Yurchenko, Ivan Salatenko, and Olha Ihnatieva. "Applying Physical Therapy on Scleroderma Patients. A Clinical Case." Acta Balneologica 61, no. 4 (2019): 283–88. http://dx.doi.org/10.36740/abal201904111.

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Introduction: Scleroderma remains one of the most severe rheumatic diseases and is characterized by a progressive course, disability, and a high level of mortality. According to world statistics, the average disease incidence rate ranges from 0.6 to 19 per 1 million, spreading out – from 4 to 242 per 1 million. An early start of physical therapy with the inclusion of new techniques in conjunction with medical treatment remains topical. Aim: To develop and experimentally test the effectiveness of a complex physical therapy program for people with a limited form of scleroderma. Clinical case: The study involved a woman with a limited form of scleroderma. At the beginning and the end of the study, laboratory studies were conducted: the level of hemoglobin, ESR, ionized calcium, Scl-70 (ANA-Screen); clinical signs were investigated: swelling of the hands, Raynaud’s phenomenon, fibrous myopathy, skin tightening assessment (according to G. Rodnan), goniometric studies and manual muscle testing. Physical therapy consisted of: daily kinesiotherapy in the form of active-passive exercises with an emphasis on fine motor skills of fingers and active exercises for the temporomandibular joint, coniferous salt bath for wrists, therapeutic massage and Kinesio taping of wrists. As a result of the study, the mobility of the joints of the upper limbs increased by an average of 5-35 °; the muscle strength increased from 3 to 5 points and the quality of life of the patient improved. Conclusions: Physical therapy made it possible to improve the mobility of the wrist and metacarpophalangeal joints, increase muscle strength, and reduce the main manifestations of the disease. The continuation of physical therapy complex will improve the quality of life of these patients and the further prognosis of treatment.
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Bilgiç, Fundagül, and İbrahim Erhan Gelgör. "Prevalence of Temporomandibular Dysfunction and its Association with Malocclusion in Children: An Epidemiologic Study." Journal of Clinical Pediatric Dentistry 41, no. 2 (January 1, 2017): 161–65. http://dx.doi.org/10.17796/1053-4628-41.2.161.

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Introduction: Malocclusion is one etiological factor of temporomandibular joint disorder (TMD). This study investigates the prevalence of TMD and the relationship between TMD and the type of occlusion. Study design: A sample of 923 children (463 girls and 460 boys, ages 7–12 years old) was grouped not only by chronological age but also by gender. The information was collected on functional occlusion (anterior and lateral sliding, interferences), dental wear, mandibular mobility (maximal opening, deflection, deviation), and temporomandibular joint and muscular pain recorded by palpation. Results: Headache was the only symptom of temporomandibular dysfunction (TMD) reported by the children. The results showed that one or more clinical signs were recorded in 25% of the subjects, most of which were mild in character. The prevalence increased during the developmental stages. Girls were in general more affected than boys. Conclusions: In this study, many subjects with TMD had malocclusions. Early treatment may be important in the prevention of severe TMD. Significant associations were found between different signs, and TMD was associated with posterior crossbite, anterior open bite, Angle Class II and III malocclusions, and extreme maxillary overjet.
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Костина, И., I. Kostina, В. Кочмашева, and V. Kochmasheva. "Ultrasound diagnostics of the temporomandibular joint osteoarthrosis." Actual problems in dentistry 12, no. 2 (July 26, 2016): 86–94. http://dx.doi.org/10.18481/2077-7566-2016-12-2-86-94.

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<p class="p1"><span class="s1">The article describes the sensitivity, speci city and accuracy of ultrasound diagnostics of the early stages of of the temporomandibular joint (TMJ) osteoarthritis (OA). The study involved 16 patients with TMJ OA (1 man, 15 women; median age – 56,1±3, and 57 years) and 12 volunteers with normal TMJ (3 men, 9 women; median age – 25,4±2,7 years). Clinical, radiographic, and ultrasonic examination of the TMJ was conducted. The echogram detected thickening of the joint capsule to accompany the TMJ. The width of the front, middle and rear parts of the joint gap was narrower than in the comparison group. The width of the capsule-cervical space in the TMJ patients ranged from 0.5 to 4 mm. In 18.8% of patients with the TMJ capsule width-cervical space was more than 1.9 mm, which is an indirect sign of synovitis. In the descriptions of linear tomograms (TMG) and echogram in patients with TMJ OA were identi ed: subchondral sclerosis, of the joint space narrowing, attening of the limited mobility of the lower jaw head, marginal osteophytes, small subchondral cysts, effusion. The linear tomograms TMJ diagnostic accuracy is 79,2%. The Ultrasonic diagnostics is informative during at the early stages of the TMJ, the diagnostic accuracy was being 59%. TMG and ultrasonic diagnostics of the AO TMJ are not the alternative methods of research. When diagnosing the of early stages of TMJ OA, and determining secondary synovitis priority should be given to the ultrasound. </span></p>
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Nabeshima, Fumikazu. "Determination of the Biomechanical Properties of the Temporomandibular Joint Region by Mechanical Mobility." Nihon Hotetsu Shika Gakkai Zasshi 36, no. 2 (1992): 299–313. http://dx.doi.org/10.2186/jjps.36.299.

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Israel, H. A., N. S. Ramamiurthy, R. Greenwald, and L. Golub. "The Potential Role of Doxycycline in the Treatment of Osteoarthritis of the Temporomandibular Joint." Advances in Dental Research 12, no. 1 (November 1998): 51–55. http://dx.doi.org/10.1177/08959374980120012001.

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Collagenase and gelatinase are matrix metalloproteinases (MMPs) which play an important role in tissue destruction in arthritic joints. Studies have demonstrated that tetracyclines can inhibit MMPs and prevent tissue destruction independent of their antimicrobial activity. The purpose of this pilot study is to assess the potential therapeutic role of Doxycycline in patients with advanced osteoarthritis of the temporomandibular joint (TMJ). This ongoing investigation includes patients with a diagnosis of osteoarthritis of the TMJ based on clinical and diagnostic imaging findings, symptoms (localized TMJ pain, limited mobility, dysfunction) for a minimum of 36 months, and failure of previous non-surgical and surgical modalities to alleviate the symptoms. A synovial fluid sample is collected by a saline injection and aspiration technique, followed by diagnostic arthroscopy. Patients are placed on Doxycycline 50 mg BID for three months and then undergo repeat diagnostic arthroscopy and synovial fluid collection. The samples are stored at -80°C. Collagenase activity is determined by a combination of SDS-polyacrylamide gel electrophoresis and fluorography and calculated based on the percentage of collagen alpha chains that are degraded into alphaA breakdown products. Three patients have completed the three-month course of Doxycycline thus far, and 5 joints with osteoarthritis have been analyzed. All patients were female (mean age = 35, mean duration of symptoms = 132 months) and had undergone previous bilateral arthroscopies. One patient had undergone unilateral arthroplasty. The mean collagenase activity showed 55% collagen lysis prior to Doxycycline treatment and 19% after three months of therapy. The mean gelatinase activity was 28% prior to Doxycycline treatment and 7% after three months of therapy. The mean interincisal opening was 33 mm initially and 41 mm after three months of Doxycycline. Subjectively, two of the three patients reported significant improvement in their overall symptoms, which they had not experienced over the previous three years. One patient did not experience any change in symptoms, in spite of a marked reduction in collagenase activity from 86.4% to 9.6%. Because of the very small numbers of patients enrolled in this pilot study so far, no statistically significant differences could be appreciated. However, the dramatic reduction in collagenase activity in these patients, with a long history of TMJ symptoms from osteoarthritis, suggests the potential promising role of Doxycycline in the management of osteoarthritis, and further investigation is warranted.
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Odzimek, Martyna, and Katarzyna Maj-Gnat. "Disorders of the statics of the body and the temporomandibular joint." Journal of Education, Health and Sport 11, no. 8 (August 28, 2021): 369–80. http://dx.doi.org/10.12775/jehs.2021.11.08.041.

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INTRODUCTION The temporomandibular joint is a synovial, complex (hinge-sliding) joint that connects the temporal bone with the mandible by means of an articular disc. Temporomandibular joint dysfunctions most often concern several disease entities and include various symptoms and ailments. One of the first symptoms of the disease is pain that stems from a muscle or joint. In addition, we can observe: limitations in the mobility and range of movement of the jaw, problems with chewing food, crackles in the joint, pain in pressure and touch of the muscles, earaches and noise or changes in the appearance of the face (the so-called "square face"). Any deviation from the correct body posture is called a posture defect. OBJECTIVE The main aim of the study is to present the significant relationship between disturbed statics of the body and the temporomandibular joint, thanks to which we can explain the importance of proper planning of diagnostics as well as conducting dental and physiotherapeutic therapy. THE WEIGHT OF THE BODCIES The materials used to write the article include scientific works from 1992-2021. The data was collected using the PubMed search engine and manual filtering. 80 publications were qualified for the analysis. SUMMARY According to the analyzed literature, we believe that there is a relationship between disturbances in the body statics and the stomatognathic system. The complexity of the issue shows that it is important to conduct multi-directional and interdisciplinary therapy.
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DIJKSTRA, P. U., L. G. M. BONT, B. STEGENGA, and G. BOERING. "Angle of mouth opening measurement: realibility of a technique for temporomandibular joint mobility assessment." Journal of Oral Rehabilitation 22, no. 4 (April 1995): 263–68. http://dx.doi.org/10.1111/j.1365-2842.1995.tb00084.x.

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Silva, Maria do Socorro Medeiros da, Júlio Leite de Araújo-Júnior, Nathalia Matos de Santana, Rômulo Bezerra de Oliveira, Vitor Engrácia Valenti, Eduardo Dias-Ribeiro, Marco Antônio Farias de Paiva, and Andrey Alves Porto. "Oscillatory joint mobilization as a physiotherapeutic treatment of temporomandibular dysfunction: a case report." Revista de Odontologia da Universidade Cidade de São Paulo 31, no. 1 (August 19, 2019): 88. http://dx.doi.org/10.26843/ro_unicidv3112019p88-94.

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Introduction: The temporomandibular joint (TMJ) acts during chew, swallowing, yawning, conversation and in activities involving jaw movements. Temporomandibular Dysfunction (TMD) is a set of disorders involving the masticatory muscles in the TMJ and associated structures. Joint mobilization aims to relief pain and restoring the function of the compromised body segment, increasing its degree of mobility. Objective: We aimed to evaluate the influence of oscillatory joint mobilization on TMD. Method: A descriptive case study with a patient who presented a clinical diagnosis of TMD in the Clinical School of Physiotherapy of the Leão Sampaio School, Juazeiro do Norte, CE, Brazil, from September 3 to October 6 of 2014, twice a week, lasting 40 minutes, a total of 10 visits. Results: The patient presented a gain in the range of motion of the mouth opening (from 17 mm to 46 mm), pain relief (from grade 6 to grade 0 on the Visual Analogue Scale) and improvement in muscle function. Conclusion: Oscillatory joint mobilization in TMD may be effective in increasing mandibular range of motion and opening of the mouth, as well as in reducing TMJ pain and masticatory musculature.
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Hamada, Yoshiki, Toshirou Kondoh, Kazutoshi Kamei, and Kanichi Seto. "Disc mobility and arthroscopic condition of the temporomandibular joint associated with long-term mandibular discontinuity." Journal of Oral and Maxillofacial Surgery 59, no. 9 (September 2001): 1002–5. http://dx.doi.org/10.1053/joms.2001.25825.

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Meikle, M. C. "Remodeling the Dentofacial Skeleton: The Biological Basis of Orthodontics and Dentofacial Orthopedics." Journal of Dental Research 86, no. 1 (January 2007): 12–24. http://dx.doi.org/10.1177/154405910708600103.

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Orthodontic tooth movement is dependent upon the remodeling of the periodontal ligament and alveolar bone by mechanical means. Facial sutures are also fibrous articulations, and by remodeling these joints, one can alter the positional relationships of the bones of the facial skeleton. As might be expected from the structure and mobility of the temporomandibular joint (TMJ), this articulation is more resistant to mechanical deformation, and whether functional mandibular displacement can alter the growth of the condyle remains controversial. Clinical investigations of the effects of the Andresen activator and its variants on dentofacial growth suggest that the changes are essentially dento-alveolar. However, with the popularity of active functional appliances, such as the Herbst and twin-block based on ’jumping the bite’, attention has focused on how they achieve dentofacial change. Animal experimentation enables informed decisions to be made regarding the effects of orthodontic treatment on the facial skeleton at the tissue, cellular, and molecular levels. Both rat and monkey models have been widely used, and the following conclusions can be drawn from such experimentation: (1) Facial sutures readily respond to changes in their mechanical environment; (2) anterior mandibular displacement in rat models does not increase the mitotic activity of cells within the condyle to be of clinical significance, and (3) mandibular displacement in non-human primates initiates remodeling activity within the TMJ and can alter condylar growth direction. This last conclusion may have clinical utility, particularly in an actively growing child.
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Ancillao, Andrea, Filippo Camerota, Marco Castori, Giorgio Albertini, Manuela Galli, and Claudia Celletti. "Temporomandibular joint mobility in adult females with Ehlers-Danlos syndrome, hypermobility type (also known as joint hypermobility syndrome)." Journal of Cranio-Maxillary Diseases 1, no. 2 (2012): 88. http://dx.doi.org/10.4103/2278-9588.105697.

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Feng, Yaping, Wei Fang, Cheng Li, Huilin Guo, Yingjie Li, and Xing Long. "The expression of high-mobility group box protein-1 in temporomandibular joint osteoarthritis with disc perforation." Journal of Oral Pathology & Medicine 45, no. 2 (June 17, 2015): 148–52. http://dx.doi.org/10.1111/jop.12336.

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UMPHLET, RANDALL C., ANN L. JOHNSON, JOANNE C. EURELL, and JOHN LOSONSKY. "The Effect of Partial Rostral Hemimandibulectomy on Mandibular Mobility and Temporomandibular Joint Morphology in the Dog." Veterinary Surgery 17, no. 4 (July 1988): 186–93. http://dx.doi.org/10.1111/j.1532-950x.1988.tb00996.x.

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Iqbal, Priyanka Rishi, and Siddharth Sen. "Comparison of two different techniques of mobilization in mechanical neck pain with decrease temporomandibular joint mobility." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 25, 2020): 7618–23. http://dx.doi.org/10.26452/ijrps.v11i4.4106.

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Pain in the anatomic region of neck is known as mechanical neck pain which is primarily caused by overuse of a normal anatomical structure, secondary to injury and deformity of anatomical structure. Also, mechanical neck pain can be defined as generalized neck pain provoked by sustained neck postures, neck movement, and pain on palpation of cervical musculature without pathologies. Restrictions of the neck movement occur and forced movement on the neck may worsen the pain. Mechanical neck pain is also known as nonspecific neck pain. It is a common complaint which affects 45-54% of the general population. The incidence of neck pain is higher in women (15%) than men (9%). High prevalence of neck pain was reported in desk job workers. 1-year prevalence of neck pain and work-related neck pain was reported as 43.3% and 28.3%. To compare the effect of Maitland and Mulligan mobilization with myofascial release on mechanical neck pain with decreased temporomandibular joint mobility. Total 45 subjects were selected and divided into three groups by random sampling method. This study concludes that Maitland mobilization and Mulligan mobilization are effective in mechanical neck pain with TMJ disability.
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Chaves, Thaís Cristina, Débora Bevilaqua Grossi, Anamaria Siriani de Oliveira, Fabiana Bertolli, Amanda Holtz, and Dirceu Costa. "Correlation between signs of temporomandibular (TMD) and cervical spine (CSD) disorders in asthmatic children." Journal of Clinical Pediatric Dentistry 29, no. 4 (July 1, 2005): 287–92. http://dx.doi.org/10.17796/jcpd.29.4.h22m675275041q01.

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Neck accessory respiratory muscles and mouth breathing suggest a direct relationship among asthma, Temporomandibular (TMD) and Cervical Spine (CSD) Disorders. This study was performed to evaluate and correlate TMD, CSD in asthmatic and non-asthmatic. Thirty asthmatic children (7.1 ± 2.6 years old), 30 non-asthmatic predominantly mouth breathing children (Mouth Breathing Group - MBG) (8.80 ± 1.61 years) and 30 non-asthmatic predominantly nasal breathing children (Nasal breathing Group – NBG) (9.00 ± 1.64 years) participated in this study and they were submitted to clinical index to evaluate stomatognathic and cervical systems. Spearman correlation test and Chi-square were used. The level of significance was set at p&lt;0.05. Significant frequency of palpatory tenderness of temporomandibular joint (TMJ), TMJ sounds, pain during cervical extension and rotation, palpatory tenderness of sternocleidomastoids and paravertabrae muscles and a severe reduction in cervical range of motion were observed in AG. Both AG and MBG groups demonstrated palpatory tenderness of posterior TMJ, medial and lateral pterygoid, and trapezius muscles when compared to NBG. Results showed a positive correlation between the severity of TMD and CSD signs in asthmatic children (r = 0.48). No child was considered normal to CSD and cervical mobility. The possible shortening of neck accessory muscles of respiration and mouth breathing could explain the relationship observed between TMD, CSD signs in asthmatic children and emphasize the importance of the assessment of temporomandibular and cervical spine regions in asthmatic children.
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Machoň, Vladimír, Jitka Levorová, Michal Beňo, Dušan Hirjak, Milan Drahoš, and René Foltán. "Evaluating the Effect of Conservative Therapy in Patients with Wilkes Stage III Temporomandibular Joint Derangement." Prague Medical Report 122, no. 4 (2021): 269–77. http://dx.doi.org/10.14712/23362936.2021.24.

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The authors evaluated effects of physiotherapy in patients experiencing Wilkes III temporomandibular joint (TMJ) derangement with clinically limited joint mobility, but no pain. The group consisted of 31 patients with unilateral temporomandibular joint involvement, 3 men and 28 women (average age was 30.93, ranging from age 12 to 61). None of the patients in the group had experienced any previous TMJ therapy. The patients underwent conservative therapy in the form of home exercise (mobilisation and isometric exercises) as the first step in treatment. The authors evaluated the improvement in jaw movement (maximal interincisal opening – MIO) and the patients’ subjective assessments of their condition. Disc position before and after two months of exercise was also evaluated using ultrasound examination. The average MIO value in patients before starting the exercises was 33.5 mm, and after two months of exercises, 42.4 mm. Subjective assessment by patients: 26 patients (83%) described their condition as completely satisfactory, not requiring further therapy. Of these patients, ultrasound examination showed 10 patients with complete disc reduction, 9 patients with a change in disc displacement with reduction, and 7 patients with a continuing (unchanged) state of disc displacement. Results of our study show the effect of conservative therapy in patients with painless TMJ due to disc displacement (WIII). Effect of home exercises which were easy to perform, simple and acceptable to the patient were demonstrated.
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Hamsen, Uwe, Oliver Kamp, Chris Kaczmarek, Mirko Aach, Christian Waydhas, Thomas A. Schildhauer, and Oliver Jansen. "Percutaneous Dilatational Tracheostomy in Ankylosing Spondylitis (Bechterew Disease) Is Feasible and Not Associated With Higher Complication Rates." Journal of Intensive Care Medicine 33, no. 7 (November 16, 2016): 420–23. http://dx.doi.org/10.1177/0885066616677959.

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Background: Ankylosing spondylitis (AS) is a common disease with an incidence of approximately 0.5% in Europe, causing severe limitations of axial spine mobility and cervical kyphosis. Deformities of the cervical spine and the temporomandibular joints could increase the risk of complications while performing an intubation or tracheostomy. The percutaneous dilatational tracheostomy (PDT) is a standard procedure in intensive care medicine. However, the combination of cervical kyphosis and osteoporosis makes patient positioning challenging. Therefore, one could conclude that patients with AS are not candidates for PDT, but neither studies nor case reports yet reported about feasibility of this procedure in AS. Methods: Retrospective analysis at a level 1 trauma center of patient records from 2002 to 2016, assessing all patients with AS and PDT. Results: A total of 31 patients with AS have been subjected to PDT. All PDTs were performed using the modified Ciaglia single-step dilatational technique. Neither cardiopulmonary nor surgical complications occurred during the procedure. One patient received a change of the existing airway prior to the procedure; a small nasal tube was changed for a laryngeal mask. Conclusion: Although head positioning may be challenging, PDT should be taken into consideration for patients with AS. In the hands of an experienced doctor, it is safe and feasible.
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42

Li, Cheng, Hengxing Cai, Qinggong Meng, Yaping Feng, Huilin Guo, Wei Fang, and Xing Long. "IL-1β mediating high mobility group box protein-1 expression in condylar chondrocyte during temporomandibular joint inflammation." Journal of Oral Pathology & Medicine 45, no. 7 (December 16, 2015): 539–45. http://dx.doi.org/10.1111/jop.12401.

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43

Nordahl, Silvi, Per Alstergren, Anna Appelgren, Björn Appelgren, Sören Eliasson, and Sigvard Kopp. "Pain, tenderness, mandibular mobility, and anterior open bite in relation to radiographic erosions in temporomandibular joint disease." Acta Odontologica Scandinavica 55, no. 1 (January 1997): 18–22. http://dx.doi.org/10.3109/00016359709091935.

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44

Macedo De Sousa, Bruno, Nansi López-Valverde, Antonio López-Valverde, Francisco Caramelo, Javier Flores Fraile, Julio Herrero Payo, and María João Rodrigues. "Different Treatments in Patients with Temporomandibular Joint Disorders: A Comparative Randomized Study." Medicina 56, no. 3 (March 5, 2020): 113. http://dx.doi.org/10.3390/medicina56030113.

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Background and Objectives: Temporomandibular joint disorders (TMJDs) are associated with pain and reduced jaw mobility. The aim of this study was to compare the outcome of patients with TMJ arthralgia when submitted to four different treatment modalities, in some cases using intra-articular injections of substances with anti-inflammatory properties and in others, a more conservative approach consisting only of a bite splint. Materials and Methods: The sample was made up of 80 patients, randomly distributed into 4 groups of 20 patients each. Each patient was given a nocturnal bite splint. One of the groups was treated with the bite splint only, while each patient in the other 3 was injected with betamethasone, sodium hyaluronate, or platelet-rich plasma in addition to using the bite splint. Two variables were assessed, namely pain intensity between 0 to 10 according to the visual analogue scale and maximum pain-free mouth opening in mm. The patients were evaluated at four different points: at the beginning of the treatment, as well as one week, one month and six months after initiation. Results: The results showed that maximum pain-free mouth opening improved in all the groups that made up the sample, with either a reduction in pain severity or with no pain. However, the group injected with platelet-rich plasma yielded the best results after six months, while patients treated with sodium hyaluronate or betamethasone obtained the best results at the end of the first week. Conclusions: We concluded that all the treatments used caused a reduction in pain and increased pain-free mouth opening. The splint combined with the platelet-rich plasma injection achieved long-term success.
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Sato, S., and H. Kawamura. "Changes in condylar mobility and radiographic alterations after treatment in patients with non-reducing disc displacementof the temporomandibular joint." Dentomaxillofacial Radiology 35, no. 4 (July 2006): 289–94. http://dx.doi.org/10.1259/dmfr/92464710.

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46

Fong, S. S. M., S. S. M. Ng, W. S. Luk, and D. J. MacFarlane. "Effects of qigong training on temporomandibular, cervical and shoulder joint mobility and sleep problems in survivors of nasopharyngeal cancer." Physiotherapy 101 (May 2015): e392. http://dx.doi.org/10.1016/j.physio.2015.03.616.

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47

Ke, J., X. Long, Y. Liu, Y. F. Zhang, J. Li, W. Fang, and Q. G. Meng. "Role of NF-κB in TNF-α-induced COX-2 Expression in Synovial Fibroblasts from Human TMJ." Journal of Dental Research 86, no. 4 (April 2007): 363–67. http://dx.doi.org/10.1177/154405910708600412.

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In the temporomandibular joint (TMJ) synovium, cyclo-oxygenase-2 (COX-2) expression has been believed to be directly related to joint pain and synovitis. Here we investigated the role of Nuclear Factor κB (NF-κB) in the regulation of COX-2 expression in synovial fibroblasts from human TMJ induced by tumor necrosis factor-α (TNF-α). By reverse-transcriptase/polymerase chain-reaction (RT-PCR) and Western blotting analysis, TNF-α induced a dose- and time-dependent increase in COX-2 expression. Electrophoretic mobility shift assay (EMSA) revealed that transient NF-κB activation in the COX-2 promoter was triggered by TNF-α. In parallel with transient NF-κB activation, the rapid translocation of NF-κB, particularly the p65 subunit, from the cytoplasm into the nucleus was demonstrated. Pre-treatment with pyrolidine dithiocarbamate (PDTC), one of the NF-κB inhibitors, prevented binding to the COX-2 promoter and expression of COX-2 protein in response to TNF-α. These findings indicate that activation of NF-κB is responsible for TNF-α-induced COX-2 expression in synovial fibroblasts from the TMJ.
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Alstergren, Per, Malin Ernberg, Maria Kvarnström, and Sigvard Kopp. "Interleukin-1β in synovial fluid from the arthritic temporomandibular joint and its relation to pain, mobility, and anterior open bite." Journal of Oral and Maxillofacial Surgery 56, no. 9 (September 1998): 1059–65. http://dx.doi.org/10.1016/s0278-2391(98)90256-7.

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Roszkowski, Mark T. "Interleukin-1β in synovial fluid from the arthritic temporomandibular joint and its relation to pain, mobility, and anterior open bite." Journal of Oral and Maxillofacial Surgery 56, no. 9 (September 1998): 1066. http://dx.doi.org/10.1016/s0278-2391(98)90257-9.

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Kalaykova, Stanimira, Adriaan Klitsie, Corine Visscher, Machiel Naeije, and Frank Lobbezoo. "A Retrospective Study on Possible Predictive Factors for Long-term Temporomandibular Joint Degeneration and Impaired Mobility in Juvenile Arthritis Patients." Journal of Oral & Facial Pain and Headache 31, no. 2 (April 2017): 165–71. http://dx.doi.org/10.11607/ofph.1656.

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