Relevant bibliographies by topics / Model membrane penetration

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Model membrane penetration'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 February 2022

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Journal articles on the topic "Model membrane penetration"

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Säälik, Pille, Aira Niinep, Janely Pae, et al. "Penetration without cells: Membrane translocation of cell-penetrating peptides in the model giant plasma membrane vesicles." Journal of Controlled Release 153, no. 2 (2011): 117–25. http://dx.doi.org/10.1016/j.jconrel.2011.03.011.

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Xie, Xi, and Nicholas A. Melosh. "Mechanical Model of Cell Membrane Penetration by Vertical Nanowires." Biophysical Journal 102, no. 3 (2012): 205a. http://dx.doi.org/10.1016/j.bpj.2011.11.1116.

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Park, Kinam. "Unraveling the penetration: Model giant plasma membrane vesicles for study of cell-penetrating peptides." Journal of Controlled Release 153, no. 2 (2011): 105. http://dx.doi.org/10.1016/j.jconrel.2011.06.018.

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Tang, Jihui, Jie Ning, Xiaoyan Liu, Baoming Wu, and Rongfeng Hu. "A Novel Amino Acid Sequence-based Computational Approach to Predicting Cell-penetrating Peptides." Current Computer-Aided Drug Design 15, no. 3 (2019): 206–11. http://dx.doi.org/10.2174/1573409914666180925100355.

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<P>Introduction: Machine Learning is a useful tool for the prediction of cell-penetration compounds as drug candidates. </P><P> Materials and Methods: In this study, we developed a novel method for predicting Cell-Penetrating Peptides (CPPs) membrane penetrating capability. For this, we used orthogonal encoding to encode amino acid and each amino acid position as one variable. Then a software of IBM spss modeler and a dataset including 533 CPPs, were used for model screening. </P><P> Results: The results indicated that the machine learning model of Support Vector
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Montenegro, Lucia, Francesco Castelli, and Maria Sarpietro. "Differential Scanning Calorimetry Analyses of Idebenone-Loaded Solid Lipid Nanoparticles Interactions with a Model of Bio-Membrane: A Comparison with In Vitro Skin Permeation Data." Pharmaceuticals 11, no. 4 (2018): 138. http://dx.doi.org/10.3390/ph11040138.

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Differential scanning calorimetry (DSC) has emerged as a helpful technique both to characterize drug delivery systems and to study their interactions with bio-membranes. In this work, we compared idebenone (IDE)-loaded solid lipid nanoparticle (SLN) interactions with bio-membranes assessed by DSC with previous in vitro skin penetration data to evaluate the feasibility of predicting IDE skin penetration using DSC analyses. In vitro interactions experiments were performed using multi-lamellar liposomes as a model of bio-membrane. Enthalpy changes (ΔH) and transition temperature (Tm) were assesse
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Chandran, Kartik, Diane L. Farsetta та Max L. Nibert. "Strategy for Nonenveloped Virus Entry: a Hydrophobic Conformer of the Reovirus Membrane Penetration Protein μ1 Mediates Membrane Disruption". Journal of Virology 76, № 19 (2002): 9920–33. http://dx.doi.org/10.1128/jvi.76.19.9920-9933.2002.

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ABSTRACT The mechanisms employed by nonenveloped animal viruses to penetrate the membranes of their host cells remain enigmatic. Membrane penetration by the nonenveloped mammalian reoviruses is believed to deliver a partially uncoated, but still large (∼70-nm), particle with active transcriptases for viral mRNA synthesis directly into the cytoplasm. This process is likely initiated by a particle form that resembles infectious subvirion particles (ISVPs), disassembly intermediates produced from virions by proteolytic uncoating. Consistent with that idea, ISVPs, but not virions, can induce disru
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Wiethoff, Christopher M., Harald Wodrich, Larry Gerace, and Glen R. Nemerow. "Adenovirus Protein VI Mediates Membrane Disruption following Capsid Disassembly." Journal of Virology 79, no. 4 (2005): 1992–2000. http://dx.doi.org/10.1128/jvi.79.4.1992-2000.2005.

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ABSTRACT In contrast to enveloped viruses, the mechanisms involved in membrane penetration by nonenveloped viruses are not as well understood. In these studies, we determined the relationship between adenovirus (Ad) capsid disassembly and the development of membrane lytic activity. Exposure to low pH or heating induced conformational changes in wild-type Ad but not in temperature-sensitive Ad (ts1) particles that fail to escape the early endosome. Wild-type Ad but not ts1 particles permeabilized model membranes (liposomes) and facilitated the cytosolic delivery of a ribotoxin. Alterations in w
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Nakamura, Hideya, Yoichi Ebashi, and Satoru Watano. "Penetration of Gold Nanoparticle into Model Biological Membrane : MD Simulation Study." Journal of the Society of Powder Technology, Japan 50, no. 7 (2013): 485–94. http://dx.doi.org/10.4164/sptj.50.485.

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Krohn, Judith, Dominik Fischer, Helena Schneider, et al. "Modification and Clinical Application of the Inner Perivitelline Membrane Test in Different Avian Species." Veterinary Sciences 6, no. 2 (2019): 39. http://dx.doi.org/10.3390/vetsci6020039.

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The aim of this study was to adapt an inner perivitelline membrane (IPVM) test as an interspecies penetration assay for avian spermatozoa. The IPVM of different bird species was evaluated to test the penetrating ability of avian spermatozoa in an intra- and interspecies design. Isolation of the IPVM via acid hydrolysis was tested in pre-incubated chicken eggs and in six other avian species. The separation protocol was modified (time, acid concentration) to facilitate practicability. Separated membranes were evaluated with dark field microscopy for the presence of holes produced by penetrating
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Tosto, Sebastiano, Philippe Knauth, and Maria Luisa Di Vona. "Proposed Model of Water Adsorption/Desorption in a PEM Membrane." Defect and Diffusion Forum 297-301 (April 2010): 209–14. http://dx.doi.org/10.4028/www.scientific.net/ddf.297-301.209.

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This paper describes the processes of water adsorption and desorption in PE membranes for fuel cells. A simple equation is inferred assuming that the surface of the membrane is uniformly covered by adsorbed molecules to an average depth of some monolayers. The adsorption depth is only controlled by diffusion of adsorbate from the surface towards the bulk through a two-layer or multi-layer mechanisms; so the empty sites formed at the surface can accept further molecules of water. If the diffusion rate is fast enough, cumulative water uptake occurs. The uptake kinetics is described considering t
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Dissertations / Theses on the topic "Model membrane penetration"

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Vogel, Troy J. "Dynamic Behavior of Self-Assembled Langmuir Films Composed of Soluble Surfactants and Insoluble Amphiphiles." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1312333896.

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Bechtella, Leïla. "Molecular analysis of the interactions of the cell-penetrating peptide Penetratin and lipid membranes. Contributions of the lipid PIP2, biophysical approaches and benzophenone photoreactivity in model membranes." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS045.

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Les peptides vecteurs (CPP) peuvent entrer dans les cellules et y transporter des molécules biologiquement actives. De précédents travaux ont montré que les CPP pouvaient remodeler le cytosquelette d'actine, interagissaient fortement avec les lipides chargés négativement et que le PIP2 pourrait jouer un rôle dans l'internalisation de la Pénétratine. Nos expériences en DSC ont montré que la Pénétratine interagit avec les têtes polaires et influence la fluidité de la membrane de vésicules contenant du PIP2. La présence de PIP2 favorise l’interaction Pénétratine-lipide. De plus, l’estimation de l
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Magzoub, Mazin. "Cell-penetrating peptides in model membrane systems : interaction, structure induction and membrane effects /." Stockholm : Institutionen för biokemi och biofysik, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-247.

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Walter, Vivien. "Lipid membrane interaction with self-assembling cell-penetrating peptides." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAE032/document.

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Les peptides pénétrateurs de cellule (CPP) sont des oligopeptides cationiques faisant parti des vecteurs les plus étudiés dans le cadre du développement du transport ciblé de médicament à l’intérieur de l’organisme. Les applications principales sont par exemple le traitement des cancers ou la thérapie génique. Néanmoins, certaines caractéristiques des CPPs rendent leur utilisation médicale compliquée, tels que leur manque de spécificité à l’égard des cellules cibles ou la perte de leurs propriétés pénétrantes lorsqu’un cargo moléculaire leur est greffé. L’une des solutions envisagées pour réso
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Hélie, Jean. "Computational studies of cell-penetrating peptides interactions with complex membranes models." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:1f154de5-6073-4bc6-986a-397734f5f140.

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Membrane active peptides with the ability to cross the plasma membrane represent a promising class of therapeutic compounds. However, translocation efficacy and membrane toxicity of these peptides appear correlated and a better understanding of their mechanisms of action is needed to achieve the desired effect. Here, a range of coarse grain molecular dynamics simulations have been performed to systematically investigate the interactions of such cell-penetrating peptides (CPPs) with biologically relevant membranes. Challenges associated to the development of a suitable asymmetric mammalian memb
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Gehan, Pauline. "Étude des mécanismes de translocation du peptide vecteur Pénétratine sur membranes modèles formées à l’interface de gouttes." Thesis, Sorbonne université, 2021. https://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2021SORUS001.pdf.

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Les peptides vecteurs se caractérisent par leur capacité à traverser les membranes cellulaires. Ils peuvent transporter des cargaisons au sein des cellules avec une faible cytotoxicité et présentent donc un intérêt particulier pour la délivrance de molécules bioactives. Leur internalisation a lieu par endocytose et translocation directe. Bien que des partenaires d’interaction de la membrane plasmique aient été identifiés, les mécanismes moléculaires de la translocation directe restent hypothétiques et les structures clés de ces mécanismes n’ont pu être clairement identifiées. Nous avons étudié
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Engelbrecht, Tanja Nadine [Verfasser], R. [Akademischer Betreuer] Neubert, B. [Akademischer Betreuer] Dobner, and G. [Akademischer Betreuer] Brezesinski. "Impact of ceramides and penetration enhancers on the nanostructure of Stratum corneum lipid model membranes / Tanja Nadine Engelbrecht. Betreuer: R. Neubert ; B. Dobner ; G. Brezesinski." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2012. http://d-nb.info/1025352920/34.

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Saßen, Christoph. "A scanning ion conductance microscopy assay to investigate interactions between cell penetrating peptides and pore-suspending membranes." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-0023-98FD-C.

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Die Rasterionenleitfähigkeitsmikroskopie (scanning ion conductance microscopy, SICM) stellt eine kontaktfreie Methode zur Ermittlung sowohl der Topographie als auch lokalen Ionenleitfähigkeit einer Oberfläche dar. Besonders vorteilhaft ist die Vermeidung mechanischer Beeinflussung bei der Untersuchung flexibler Strukturen, z.B. Lipiddoppelschichten wie Zellen oder künstlich erzeugter Lipidmembranen. Porenüberspannende Membranen (pore-suspending membranes, PSMs) verbinden als ein Beispiel für Modellsysteme eine hohe Stabilität mit lateraler Mobilität und dem Vorhandensein wässriger Kompartiment
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Verbeek, Sarah Félice. "Effects of arginine derivatives and oligopeptides on the physical properties of model membranes." Doctoral thesis, 2020. http://hdl.handle.net/21.11130/00-1735-0000-0005-1571-4.

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McCanna, David. "Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products." Thesis, 2009. http://hdl.handle.net/10012/4338.

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The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty associated with dose selection for clinical trials. The first section of this thesis describes how in vitro methods can be used to improve the prediction of the toxicity of chemicals and ophthalmic products. The proper utilization of in vitro methods can accurately predict toxic threshold levels and reduce animal use in product development. Sections two, three and four describe t
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Books on the topic "Model membrane penetration"

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Bond, John Russell. Human skin and model membranes for permeation studies: Comparative and steady-state permeability studies on humanand hairless mouse skins, eggshell and synthetic membranes using water, mannitol, hexanol, salicylic acid and 5-fluorouracil, together with the effects of penetration enhancers'. 1986.

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Book chapters on the topic "Model membrane penetration"

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Augustynek, Martin, Adela Zemanova, Jan Kubicek, and Marek Penhaker. "Model of Drugs Penetration Through Biological Membrane." In Lecture Notes in Electrical Engineering. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24584-3_41.

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Odegard, Amy, Manidipa Banerjee, and John E. Johnson. "Flock House Virus: A Model System for Understanding Non-Enveloped Virus Entry and Membrane Penetration." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/82_2010_35.

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Alves, Isabel D., Nicolas Rodriguez, Sophie Cribier, and Sandrine Sagan. "Membrane Crossover by Cell-Penetrating Peptides: Kinetics and Mechanisms – From Model to Cell Membrane Perturbation by Permeant Peptides." In Intracellular Delivery. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-1248-5_7.

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Kawamoto, S., M. Takasu, T. Miyakawa, et al. "Free Energy of Cell-Penetrating Peptide through Lipid Bilayer Membrane: Coarse-Grained Model Simulation." In Quantum Systems in Chemistry and Physics. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-5297-9_29.

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"Interactions of Cell-Penetrating Peptides with Model Membranes." In Handbook of Cell-Penetrating Peptides. CRC Press, 2006. http://dx.doi.org/10.1201/9781420006087-14.

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Deshayes, Sébastien, May Morris, Gilles Divita, and Fédéric Heitz. "Interactions of Cell-Penetrating Peptides with Model Membranes." In Handbook of Cell-Penetrating Peptides, Second Edition. CRC Press, 2006. http://dx.doi.org/10.1201/9781420006087.ch8.

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Conference papers on the topic "Model membrane penetration"

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McNeff, Patrick S., and Brian K. Paul. "Predicting the Force Needed to Create a Compression Seal in an Ultra-Thin Elastoviscoplastic Membrane." In ASME 2016 11th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/msec2016-8638.

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In this paper, a finite element model is developed, and experimentally validated, for predicting the force required to produce a compression seal between a polycarbonate sealing boss and a 25 μm thick elastoviscoplastic hemodialysis membrane. This work leverages previous efforts to determine the conditions for hermetic sealing in a microchannel hemodialyser fabricated using hot-embossed polycarbonate microchannel laminae containing sealing boss features. Methods are developed for mechanically characterizing the thin elastoviscoplastic hemodialysis membrane. Experimental data for assessing the
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Khajeh-Hosseini-Dalasm, N., S. Ahadian, K. Fushinobu, and K. Okazaki. "Parametric Analysis of the Cathode Catalyst Layer of Proton Exchange Membrane Fuel Cells Using Artificial Neural Network." In ASME 2011 9th International Conference on Fuel Cell Science, Engineering and Technology collocated with ASME 2011 5th International Conference on Energy Sustainability. ASMEDC, 2011. http://dx.doi.org/10.1115/fuelcell2011-54640.

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A mathematical model was developed to study the cathode catalyst layer (CL) performance of a proton exchange membrane fuel cell (PEMFC). A number of CL parameters affecting its performance are implemented into the CL agglomerate model. These parameters are: saturation and eight structural parameters, i.e., ionomer film thickness covering the agglomerate, agglomerate radius, platinum and carbon loading, membrane content, gas diffusion layer penetration content and CL thickness. An artificial neural network (ANN) approach along with statistical methods was used for modeling, prediction, and anal
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Zhou, Biao, and Anh Dinh Le. "Liquid Water Effects on the Performance of a PEMFC With Serpentine-Parallel Channels." In ASME 2008 6th International Conference on Fuel Cell Science, Engineering and Technology. ASMEDC, 2008. http://dx.doi.org/10.1115/fuelcell2008-65136.

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Water management is one of the most important issues for the performance of Proton Exchange Membrane Fuel Cell (PEMFC). Understanding of water liquid behaviors in the gas-liquid flow of PEMFC is necessary for the optimization of PEMFC. In this study, a three-dimensional and unsteady PEMFC model with serpentine-parallel channels has been incorporated to investigate not only the fluid flow, heat transfer, species transport, electrochemical reaction, and current density distribution but also the behaviors of water liquid in the gas–liquid flow of the channels and porous media. The results show th
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Oh, Seungjae, Semyung Wang, Minkyu Park, and Joonha Kim. "Topology Optimization of Spacers for Maximizing Permeate Flux on Membrane Surface in Reverse Osmosis Channel." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48933.

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The objective of this study is to design spacers using fluid topology optimization in 2D crossflow Reverse Osmosis (RO) membrane channel to improve the performance of RO processes. This study is an initial attempt to apply topology optimization to designing spacers in RO membrane channel. The performance was evaluated by the quantity of permeate flux penetrating both upper and lower membrane surfaces. A coupled Navier-Stokes and Convection-Diffusion model was employed to calculate the permeate flux. To get reliable solutions, stabilization methods were employed with standard finite element met
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Friess, Brooks, and Mina Hoorfar. "Fluorescence Microscopy for the Measurement of the Surface Properties of the Gas Diffusion Layers of Fuel." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-39523.

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One of the major problems of current proton exchange membrane (PEM) fuel cells is water management. The gas diffusion layer (GDL) of the fuel cell plays an important role in water management since humidification and water removal are both achieved through the GDL. Various numerical models developed to illustrate the multiphase flow and transport in the fuel cell require the accurate measurement of the GDL properties (wettability and surface energy). In a recent study, the capillary penetration technique has been used to measure indirectly the wettability of the GDL based on the experimental he
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Bani Salim, Muath, and Xuewei Zhang. "Development and Verification of an Integrated Seawater Desalination and Renewable Energy System Model." In ASME 2021 Verification and Validation Symposium. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/vvs2021-65284.

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Abstract This work investigates the modeling and verification of seawater reverse osmosis powered by renewable energy resources (SWRO-RES). The model includes one stage of RO membranes, high pressure (HP) pump, energy recovery devices (ERD), Wind turbines (WT), photovoltaic panels (PV), and electrical grid as a back-up for the cases when there is weak penetration of the RES. Antibugging and tracing for the computer model were used as part of the code verification to discover all coding errors and check whether the computer model conforms to the SWRO specifications. After that, the calculations
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