Academic literature on the topic 'Modèle intestinal in vitro'

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Journal articles on the topic "Modèle intestinal in vitro"

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Uriot, O., C. Deschamps, M. Brun, et al. "Développement et validation d’un modèle colique in vitro de dysbiose du microbiote intestinal humain associé à l’obésité." Nutrition Clinique et Métabolisme 37, no. 2 (2023): e20. http://dx.doi.org/10.1016/j.nupar.2023.03.032.

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Krause, J.L., A. Pierzchalski, H.D. Chang, A.C. Zenclussen, M. Bauer, and G. Herberth. "Bisphenols, but not phthalate esters, modulate gene expression in activated human MAIT cells in vitro." Toxicology Reports 10 (July 6, 2023): 348–56. https://doi.org/10.1016/j.toxrep.2023.02.017.

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One route of human exposure to environmental chemicals is oral uptake. This is primarily true for chemicals that may leach from food packaging materials, such as bisphenols and phthalate esters. Upon ingestion, these compounds are transported along the intestinal tract, from where they can be taken up into the blood stream or distributed to mucosal sites. At mucosal sites, mucosal immune cells and in the blood stream peripheral immune cells may be exposed to these chemicals potentially modulating immune cell functions. In the present study, we investigated the impact of three common bisphenols
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Amamou, A., L. Yaker, C. Bôle-Feysot, G. Savoye, and R. Marion-Letellier. "Étude de l’interaction entre des dérivés du tryptophane et le récepteur aryl hydrocarbone dans un modèle in vitro de fibrose intestinale." Nutrition Clinique et Métabolisme 33, no. 1 (2019): 100. http://dx.doi.org/10.1016/j.nupar.2019.01.412.

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Vergères, Guy, Biljana Bogicevic, Caroline Buri, et al. "The NutriChip project – translating technology into nutritional knowledge." British Journal of Nutrition 108, no. 5 (2012): 762–68. http://dx.doi.org/10.1017/s0007114512002693.

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Advances in food transformation have dramatically increased the diversity of products on the market and, consequently, exposed consumers to a complex spectrum of bioactive nutrients whose potential risks and benefits have mostly not been confidently demonstrated. Therefore, tools are needed to efficiently screen products for selected physiological properties before they enter the market. NutriChip is an interdisciplinary modular project funded by the Swiss programme Nano-Tera, which groups scientists from several areas of research with the aim of developing analytical strategies that will enab
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Jackson, Tim R., Miniver Oliver, Daniel Appledorn, Tim Dale, and Kalpana Barnes. "Abstract 3084: Label-free, real-time live cell assays for 3D organoids embedded in Matrigel®." Cancer Research 82, no. 12_Supplement (2022): 3084. http://dx.doi.org/10.1158/1538-7445.am2022-3084.

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Abstract Organoid technologies are increasingly being used as in-vitro models of human development and disease as they exhibit structural, morphogenetic, and functional properties that recapitulate in vivo pathophysiology. To successfully use these models across a variety of research disciplines and applications, approaches that reduce variability and technology pipelines to image & quantify these complex cell models are required. Here, we demonstrate simple, robust workflows for monitoring and automatically quantifying features, such as morphology, growth and death of organoids using real
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Tagawa, Kozo, Akiko Kiriyama, San Yuet Lin, and Sota Fukunaga. "Development of dissolution evaluation system for drug absorption (V): Additional intestinal absorption module of in vitro 3D gastric emptying mmodel for orally disintegrating tablet." Drug Metabolism and Pharmacokinetics 61 (June 2025): 101140. https://doi.org/10.1016/j.dmpk.2025.101140.

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Losa, Marco, Michael Field, Lauren Collen, et al. "BIOACTIVE INTERLEUKIN-1 DETECTED IN IBD PATIENT INTESTINAL BIOPSIES IS A HALLMARK OF ULCERS AND CORRELATES WITH TRANSCRIPTOMIC ASSESSMENTS, INCLUDING AN ULCER-ASSOCIATED GENE MODULE." Inflammatory Bowel Diseases 30, Supplement_1 (2024): S00. http://dx.doi.org/10.1093/ibd/izae020.117.

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Abstract BACKGROUND Interleukin (IL)-1 and its post-translationally modified and released forms, IL-1α and IL-1β, have been identified as key molecules to maintain mucosal homeostasis and to drive inflammatory bowel disease (IBD). Deep cellular phenotypic, transcriptional, and in vitro data highlight the importance of IL-1-associated cytokine networks and IL-1 producing cells in severe and anti-TNF non-responsive IBD. Nevertheless, little is known about the presence of bioactive IL-1 proteins within the cell-free gastrointestinal (GI) mucosal environment and associated function in severe IBD a
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Rashid, Md Harun Or, and Feng Lin. "Magnetically Driven Biopsy Capsule Robot with Spring Mechanism." Micromachines 15, no. 2 (2024): 287. http://dx.doi.org/10.3390/mi15020287.

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In recent years, capsule endoscopes (CEs) have appeared as an advanced technology for the diagnosis of gastrointestinal diseases. However, only capturing the images limits the advanced diagnostic procedures and so on in CE’s applications. Herein, considering other extended functions like tissue sampling, a novel wireless biopsy CE has been presented employing active locomotion. Two permanent magnets (PMs) have been placed into the robots, which control the actuation of the capsule robot (CR) and biopsy mechanism by employing an external electromagnetic actuation (EMA) system. A spring has been
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Dupont, C., M. E. Bougnoux, J. Matéo, P. Saulnier, D. Payen, and M. H. Nicolas-Chanoine. "Diagnostic des candidoses profondes par PCR modèle in vitro et modèle animal." La Revue de Médecine Interne 17 (January 1996): 356s. http://dx.doi.org/10.1016/s0248-8663(97)80878-8.

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Dupont, C., M. E. Bougnoux, J. Mateo, P. Saulnier, D. Payen, and M. H. Nicolas-Chanoine. "Diagnostic des candidoses profondes par PCR. Modèle in vitro et modèle animal." Médecine et Maladies Infectieuses 27 (November 1997): 1005. http://dx.doi.org/10.1016/s0399-077x(97)80272-7.

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Dissertations / Theses on the topic "Modèle intestinal in vitro"

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Ponce, de Leon Rodriguez Maria del Carmen. "Développement d’un modèle in vitro d’inflammation intestinale par l’utilisation de lignées cellulaires humaines en co-culture pour l’étude des interactionsavec les micro-constituants alimentaires." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTG009/document.

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L’épithélium intestinal, siège de l’absorption des (micro)-nutriments est aussi le premier système de défense de l’organisme. Un déséquilibre dans l’homéostasie peut être à l’origine d’une réaction inflammatoire associée à des défauts de la barrière intestinale et de la fonction immunitaire, ainsi qu’une malabsorption des nutriments, comme rencontré dans les MICI (Maladies Inflammatoires Chroniques de l’Intestin), dans les stratégies de fortification en micronutriments et les pathologies non transmissibles (obésité). Il est donc important de trouver des moyens d’action, via l’alimentation par
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Roy, Isabelle. "Contribution à la mise en place d'un modèle "in vitro" prédictif de l'absorption et du métabolisme intestinal." Paris 5, 1994. http://www.theses.fr/1994PA05P159.

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Fleury, Mickaël. "Impact de traitements antibiotiques sur la flore digestive du porcelet : Etude in vivo et développement d'une approche en système de fermentation in vitro." Thesis, Rennes 1, 2015. http://www.theses.fr/2015REN1B002/document.

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Dans le contexte de l'antibiorésistance, l'objet de ce doctorat vise à évaluer l'impact d'antibiotiques sur le microbiote intestinal de porcelets. La colistine et le ceftiofur, pour lesquels les résistances incluent essentiellement et respectivement mutations chromosomiques et gènes plasmidiques, ont été utilisés. La colistine a significativement réduit la population des entérobactéries, mais aucun E. coli résistant n'a été détecté. L'administration de ceftiofur a eu un impact limité sur les populations bactériennes composant l'écosystème digestif mais a conduit à une forte sélection et à la d
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Altay, Gizem. "Towards the development of biomimetic in vitro models of intestinal epithelium derived from intestinal organoids." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/664864.

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Intestinal epithelium is highly specialized tissue organized into crypt-villus units relevant for their effective barrier function and nutrient absorption. In the crypt units reside the proliferative intestinal stem cells (ISCs) that divide and differentiate while migrating along the villi to generate the epithelium. The proliferation, migration and differentiation of ISCs is governed by the tightly controlled spatio-chemical gradients of ISC niche factors; bone morphogenic protein (BMP), wingless/Int (Wnt) and epidermal growth factor (EGF) pathway modulators. In vitro models of the intestinal
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Gérémie, Lauriane. "Development of an in-vitro intestinal model featuring peristaltic motion." Thesis, Sorbonne université, 2019. http://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2019SORUS118.pdf.

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Le Gut-on-chip fait partie d'un thème de recherche plus générale, appelez Organ-on-chip qui a pour objectif de développer des modèles in-vitro qui récapitulent des caractéristiques essentielles de l'organe d'intérêt. Dans le cas de l'intestin, les Gut-on-chip plateformes ont été principalement développés pour reconstituer soit l'architecture 3D de l'intestin, soit sa dynamique et plus particulièrement le péristaltisme. Durant ma thèse j'ai développé une nouvelle et polyvalente Gut-on-chip, présentant ces deux aspects du micro-environnement intestinale. Cette Peristalsis-on-chip nous a permis d
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Garcia, Rodriguez Alba. "The applicability of in vitro models of the intestinal barrier for the risk assessment of engineered nanomaterials used as food additives." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/669883.

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Los avances en el campo de la nanotecnología han permitido desarrollar una gran diversidad de nanomateriales sintetizados artificialmente (NMs), los cuales presentan nuevas y prometedoras aplicaciones en diversas industrias. Debido a sus exclusivas propiedades, los NMs son utilizados en la comida o envoltorios de comida como mejora de textura, color, sabor, estabilizador, etc. A pesar de sus propiedades innovadoras, existe un aumento en la preocupación sobre si las nanopartículas (NPs) de dióxido de titanio (TiO2) puedan llegar a producir efectos adversos en la salud humana. La Agencia Intern
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SUNDARAM, TAMIL SELVI. "ESTABLISHING IN VITRO INTESTINAL EPITHELIAL CELL MODELS IN TRANSLATIONAL ANIMAL NUTRITION." Doctoral thesis, Università degli Studi di Milano, 2022. https://hdl.handle.net/2434/944348.

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Immunomodulatory nutrients as the omega-3 polyunsaturated fatty acids (n-3 PUFA) and citrus pectins (CPn) are reported to beneficially affect the host intestinal immunity. However so far, the biological pathways modulated by these nutrients in intestinal inflammation at the level of intestinal epithelial layer (IEL) remains elusive. To bridge this knowledge gap, the aim of our present study was set in the direction to delineate the effects of n-3 PUFA in porcine IPEC-J2 cell line under (LPS) stress conditions underpinning pig nutrition, combining the state-of-the-art cell-based assays an
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Kratz, Jadel Müller. "Implementação e aplicação do modelo in vitro com células Caco-2 para estudo da permeabilidade intestinal de fármacos." Florianópolis, SC, 2011. http://repositorio.ufsc.br/xmlui/handle/123456789/95611.

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Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011<br>Made available in DSpace on 2012-10-26T03:54:33Z (GMT). No. of bitstreams: 1 294811.pdf: 4760452 bytes, checksum: fa236ca094f2d6addc744e0ad2b1cb85 (MD5)<br>A absorção oral de um fármaco é controlada fundamentalmente por dois fatores: a solubilidade aquosa/dissolução e a permeabilidade intestinal. Portanto, a determinação dessas características ainda nas fases de descoberta e desenvolvimento de fármacos pode prover moléculas com ótimo perfil biofa
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Langan, Laura. "Fish intestinal cultures for ecotoxicological studies : in vitro and primary culture models." Thesis, University of Plymouth, 2017. http://hdl.handle.net/10026.1/9486.

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Ecotoxicity testing of chemicals for environmental risk assessment is an area where a high number of vertebrates are used across a variety of industrial sectors. The application of the 3Rs in toxicity testing using fish address both the ethical and societal concerns around this issue in addition to the increasing legislative requests for the incorporation of animal alternatives. This thesis aims to highlight the potential of 3D cell culture models to "bridge the gap" between in vitro and in vivo screening procedures for testing of chemicals with the potential to persist or bioaccumulate thereb
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Deschamps, Charlotte. "Impact du poids corporel et d'une perturbation antibiotique sur le microbiote intestinal du chien : simulation in vitro et stratégies de restauration." Electronic Thesis or Diss., Université Clermont Auvergne (2021-...), 2023. http://www.theses.fr/2023UCFA0055.

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Différentes tailles de chiens sont associées à des variations de la physiologie digestive, principalement liées au colon et à ses microorganismes résidents. Ce microbiote intestinal joue un rôle clé en santé, soutenant les processus nutritionnels, immunologiques et physiologiques. Néanmoins, les maladies ou l'antibiothérapie peuvent altérer l'équilibre microbien et induire un état perturbé appelé dysbiose. Pour restaurer l'eubiose du microbiote, de nouvelles stratégies de restauration ont été développées telles que les pré, pro ou postbiotiques. Cependant, peu d'études ont évalué leurs effets
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Books on the topic "Modèle intestinal in vitro"

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Mahmood, Belal A. I. Studies on the effects of cholera toxin and fish oil on intestinal secretion in vitro. University of Manchester, 1994.

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Nicklin, Paul Leslie. Amino acid, peptide and drug transport across monolayers of human intestinal (CAC0-2) cells in vitro. Aston University. Department of Pharmaceutical Sciences., 1993.

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Kik, Maria Jacoba Leonarda. Effects of lectins in legume seeds on the structure and function of the small intestinal mucosa: In vivo and in vitro studies. [s.n.], 1991.

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Essai n° 431 : Corrosion Cutanée In Vitro : Essai sur Modèle de Peau Humaine. OECD, 2014. http://dx.doi.org/10.1787/9789264224216-fr.

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Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2019. http://dx.doi.org/10.1787/9789264264625-fr.

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Essai n° 431: Corrosion cutanée in vitro :Essai sur modèle de peau humaine. OECD, 2004. http://dx.doi.org/10.1787/9789264071155-fr.

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Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2015. http://dx.doi.org/10.1787/9789264242784-fr.

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Essai n° 431 : Corrosion cutanée in vitro : Essai sur modèle de peau humaine. OECD, 2013. http://dx.doi.org/10.1787/9789264203839-fr.

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Pietzonka, Peter. A critical evaluation of colloidal delivery systems for drug transfer into intestinal cells in vitro. 2001.

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Gutenberg-Universität, Johannes, ed. Keine Änderung der Synaptischen Strukturen in Vitro im Pinealorgan der Ratte durch Delta-Sleep-Inducing-Peptide (DSIP) und Vasoactive-Intestinal-Peptide (VIP). 1995.

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Book chapters on the topic "Modèle intestinal in vitro"

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Sambruy, Yula, S. Ferruzza, G. Ranaldi, and I. De Angelis. "Intestinal Cell Culture Models." In Cell Culture Methods for In Vitro Toxicology. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-017-0996-5_7.

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Almeida, Hugo, Amélia C. F. Vieira, João Teixeira, et al. "Cell-Based Intestinal In Vitro Models for Drug Absorption Screening." In Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35529-5_94.

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Almeida, Hugo, Amélia C. F. Vieira, João Teixeira, et al. "Cell-Based Intestinal In Vitro Models for Drug Absorption Screening." In Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-73317-9_94-1.

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Morita, Atsuya, Mizuho Nakayama, Hiroko Oshima, and Masanobu Oshima. "In Vitro and In Vivo Models for Metastatic Intestinal Tumors Using Genotype-Defined Organoids." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3331-1_2.

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Wang, Tingting, Xianglong Li, and Qinghua Liao. "Stool and Intestinal Microbiota Examination." In In Vitro Diagnostic Industry in China. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-3110-1_20.

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Lallés, J. P., and I. P. Oswald. "Chapter 8: Techniques for investigating gut function in vivo, ex vivo and in vitro in monogastric farm animals." In Intestinal health. Wageningen Academic Publishers, 2015. http://dx.doi.org/10.3920/978-90-8686-792-9_8.

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Chan, Wing Hei, Diana Micati, Rebekah M. Engel, et al. "Modeling Intestinal Carcinogenesis Using In Vitro Organoid Cultures." In Methods in Molecular Biology. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3331-1_5.

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Jardé, Thierry, Genevieve Kerr, Reyhan Akhtar, and Helen E. Abud. "Modelling Intestinal Carcinogenesis Using In Vitro Organoid Cultures." In Methods in Molecular Biology. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7568-6_4.

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Chen, Yun, Chuan Li, Ya-Hui Tsai, and Sheng-Hong Tseng. "Intestinal Crypt Organoid: Isolation of Intestinal Stem Cells, In Vitro Culture, and Optical Observation." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/7651_2017_21.

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Smith, Philip L. "Methods for Evaluating Intestinal Permeability and Metabolism in Vitro." In Pharmaceutical Biotechnology. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-1863-5_2.

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Conference papers on the topic "Modèle intestinal in vitro"

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Corsello, Lorenzo, Simona Marra, Adriana Saavedra, et al. "Characterization of an in vitro model of intestinal cells as a test-bed for mCIPO therapies." In 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2024. https://doi.org/10.1109/embc53108.2024.10782258.

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Stan, Miruna, and Alina Strugari. "Nanoparticle Intestinal Transport Characterization Using In Vitro Co-Culture Models." In 1st International Online Conference on Nanomaterials. MDPI, 2018. http://dx.doi.org/10.3390/iocn_2018-1-05480.

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Elisa Ramos Magalhães, Ana, Juliana Alves Macedo, and Mônica Cristina Lopes do Carmo. "AVALIAÇÃO DO EXTRATO DE FOLHAS DE PASSIFLORA EDULIS EM MODELO IN VITRO DE INFLAMAÇÃO INTESTINAL." In XXV Congresso de Iniciação Cientifica da Unicamp. Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-77869.

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Lukyanov, Alexandr D., Danila Yu Donskoy, Miroslav A. Vernezi, Maria S. Mazanko, and Svetlana G. Studennikova. "EXPERIENCE IN DEVELOPING MODELS OF ARTIFICIAL GASTROINTESTINAL TRACTS OF ANIMALS." In XXVII savetovanje o biotehnologiji. University of Kragujevac, Faculty of Agronomy, 2022. http://dx.doi.org/10.46793/sbt27.193l.

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For „in-vitro“ experimental study of the effect of probiotics on the development of microbiota of poultry and domestic animals, a line of „SHIME“ – like models of artificial gastrointestinal tracts in the form of complexes of miniature bioreactors with microcontroller control and monitoring systems was created. Experience in operating this equipment in an experimental study of the effect of prebiotics on the development of intestinal microbiota has allowed to establish a number of features and limitations, which are brought in this paper. The peculiarities of setting up peristaltic pumps, magn
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Gong, Liyuan, Kevin Rivera, Birendra Chaudhary, et al. "Microfluidic Bi-Axial Cell Stretching Platform for Intestinal Epithelial Cell Modeling." In ASME 2024 Fluids Engineering Division Summer Meeting collocated with the ASME 2024 Heat Transfer Summer Conference and the ASME 2024 18th International Conference on Energy Sustainability. American Society of Mechanical Engineers, 2024. http://dx.doi.org/10.1115/fedsm2024-130499.

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Abstract Intestinal epithelial cells encounter intricate mechanical and physiological stimuli within the intestinal microenvironment. Establishing a precise and dynamic in vitro model is essential to exert control over cellular behaviors. As microfluidic devices offer unparalleled versatility and precision for replicating physiological conditions, this tool has attracted increasing attention in broad applications. This study presents a novel microfluidic bi-axial 9-well cell stretching system designed for cells using two common intestinal epithelial cell lines (Caco2 and HT29) as the models. T
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Williams, Courtney M., Jessica L. Harper, Hui Huang, et al. "Abstract 2644: In vivo and in vitro stem cell models suggest a role for LGR5 in regulating intestinal epithelial lineage specification." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2644.

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Hoppensteadt, D., A. Kumar, J. Fareed, and J. Mardigian. "STUDIES ON THE ANTICOAGULANT AND ANTITHROMBOTIC ACTIONS OF DERMATANS AND THEIR SULFATED DERIVATIVES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643241.

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Non-antithrombin III mediated effects such as interaction with heparin cofactor II, modulation of endothelium and polymorphonuclear leukocytes contribute to the overall antithrombotic effects of glycosaminoglycans. In order to study the role of these dermatans, we investigated their in vitro anticoagulant effects using the clot based (PT, APTT, TT, and Heptest), antiprotease (anti IIa and anti Xa) and Thromboplastin C activated fibrinopeptide A generation test. The in vivo antithrombotic actions were investigated, against activated and non activated prothrombin complex concentrates, and in com
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Boyd, Abigail, Joey Talbert, and Nuria Acevedo. "Addition of cholesterol esterase substantially enhances phytosterol ester bioaccessibility in emulsions with different droplet sizes using a standardized in vitro digestion model." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/oplq4898.

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In vitro digestion models are an important tool for the evaluation of foods and supplements, especially foods containing nutraceuticals and bioactive compounds. The INFOGEST network of researchers has published multiple iterations of a static in vitro digestion protocol for the study of food digestion. However, the protocol currently lacks cholesterol esterase (CE) activity during the intestinal phase, and few studies have attempted to evaluate its incorporation into the model. In the present study, the effect of additional CE on phytosterol ester (PSE) bioaccessibility in oil-in-water emulsio
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Hippenstiel, S., B. Brell, C. Zu Dohna, et al. "Adrenomedullin Reduces Sepsis-Related Intestinal Epithelial PermeabilityIn VivoandIn Vitro." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1162.

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Alno, N., F. Clipet, P. Pellen-Mussi, G. Cathelineau, and G. De Mello. "Mise au point d’un modèle de culture tridimensionnelle pour l’évaluation de substituts osseux in vitro." In 56ème Congrès de la SFMBCB. EDP Sciences, 2011. http://dx.doi.org/10.1051/sfmbcb/20115602007.

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Reports on the topic "Modèle intestinal in vitro"

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Shpigel, Nahum, Raul Barletta, Ilan Rosenshine, and Marcelo Chaffer. Identification and characterization of Mycobacterium paratuberculosis virulence genes expressed in vivo by negative selection. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7696510.bard.

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Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of a severe inflammatory bowel disease (IBD) in ruminants, known as Johne’s disease or paratuberculosis. Johne’s disease is considered to be one of the most serious diseases affecting dairy cattle both in Israel and worldwide. Heavy economic losses are incurred by dairy farmers due to the severe effect of subclinical infection on milk production, fertility, lower disease resistance and early culling. Its influence in the United States alone is staggering, causing an estimated loss of $1.5 billion to the agriculture indu
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Pirarat, Nopadon. Efficacy of encapsulated yeast (Saccharomyces cerevisiae)against streptococcosis in tilapia. Chulalongkorn University, 2015. https://doi.org/10.58837/chula.res.2015.79.

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S. cerevisiae JCM 7255 from brewing industry was tested to be a possible probiotic candidate in aquaculture together with encapsulation and freeze-drying technique. In vitro viability and morphology analysis of probiotic during storage and during transient with stimulated tilapia gut and bile conditions were evaluated as well as In vivo growth performance efficacy, gut mucosal immune parameters and anti-Streptococcal activity. The In vitro results showed that the viabilities of encapsulated yeasts remained in the high number after storage in room temperature for 14 days, while the viability of
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Harpaz, Sheenan, Steven G. Hughes, and Pinhas Lindner. Optimization of Diet for Post Larvel/Juvenile Sea Bass and Hybrid Stripped Bass Based on Enzymatic Profiles of their Digestive Tracts. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604924.bard.

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The overall goal of this research work was to identify the main proteolytic activities which take place in the digestive tracts of young bass fish, and use the knowledge acquired in order to improve feed protein utilization in juvenile fish based on their digestive capacity. The results of the work clearly showed that the young fish possess the entire profile of proteolytic enzymes which is found in adult fish. Yet, in the young fish the level of activity is substantially lower per gram tissue (or gram protein) as compared with the activity found in the digestive tracts of the same fish at an
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