Relevant bibliographies by topics / Modern antihypertensives drugs

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Modern antihypertensives drugs'

Author: Grafiati
Published: 4 June 2021
Last updated: 15 February 2022

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Journal articles on the topic "Modern antihypertensives drugs"

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Podzolkov, V. I., A. I. Tarzimanova, and Z. O. Georgadze. "Modern Principles of Treatment of Uncontrolled Hypertension." Rational Pharmacotherapy in Cardiology 15, no. 5 (2019): 736–41. http://dx.doi.org/10.20996/1819-6446-2019-15-5-736-741.

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Despite the current possibilities of using different classes of antihypertensive drugs that effectively reduce blood pressure and significantly improve the long-term prognosis of patients, the problem of uncontrolled arterial hypertension has not lost its importance and its solution in a particular clinical situation often remains very difficult. The term "uncontrolled arterial hypertension" can be used in all cases where arterial pressure has not been achieved. The true prevalence of uncontrolled arterial hypertension has not been established, and its study is hampered primarily by the fact t
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2

Morozova, T. E. "Combined antihypertensive therapy in the light of modern recommendations: strategy of one tablet." Systemic Hypertension 15, no. 4 (2018): 92–96. http://dx.doi.org/10.26442/2075082x.2018.4.180110.

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The review focuses on the main strategies of antihypertensive therapy set out in the 2018 ESC/ESH recommendations. The basis of antihypertensive therapy consists of five main classes of antihypertensive drugs, which should form the basis of the combined drug antihypertensive therapy in most patients. The single pill strategy is to take advantage of fixed combinations as a starting antihypertensive therapy for most patients. Among the fixed combinations, the combination of an ACE inhibitor with a diuretic (Noliprel®) remains one of the most preferred for antihypertensive therapy, since In addit
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Sayutina, E. V. "Fixed combinations in modern hypertension treatment algorithms." Cardiovascular Therapy and Prevention 17, no. 6 (2018): 86–94. http://dx.doi.org/10.15829/1728-8800-2018-6-86-94.

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Modern appropriate treatment of hypertension involves the use of combination antihypertensive therapy. According to updated version of European Society of Cardiology 2018 guidelines, renin-angiotensin-aldosterone system blockers must be used as first-line drugs, including in combination with hydrochlorothiazide. This article presents the algorithms for the management of patients with uncomplicated and asymptomatic (with target lesions) arterial hypertension. It also described the management of patients with concomitant cardiovascular, cerebrovascular, renal pathology and diabetes mellitus, and
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Soboleva, M. S., and E. E. Loskutova. "Analysis of acquisition and the monthly cost of antihypertensive therapy with modern fixed-dose combinations in the Far Eastern Federal District." FARMAKOEKONOMIKA. Modern Pharmacoeconomic and Pharmacoepidemiology 14, no. 1 (2021): 41–49. http://dx.doi.org/10.17749/2070-4909/farmakoekonomika.2021.061.

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Objective: analyzing the acquisition and monthly costs for patients on modern fixed-dose antihypertensive combinations in three regions of the Far Eastern Federal District.Material and methods. Intra-group analysis of retail of antihypertensive drugs for 2019 in drugstores of the Khabarovsk Region, Sakhalin Region, Amur Region (n=100) was carried out. The calculation of the monthly cost of therapy was performed and total sales indicators were identified. Statistical analysis: dispersion analysis, Spearman's rank correlation coefficient, Kruskal–Wallis test.Results. The maximum demand in patien
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Pinchuk, Tatiana V., and Natalia V. Orlova. "The place of fixed antihypertensive drugs in modern therapy of arterial hypertension." Systemic Hypertension 17, no. 4 (2021): 44–48. http://dx.doi.org/10.26442/2075082x.2020.4.200035.

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The article provides information on modern approaches to the treatment of arterial hypertension. The historical information about therapy with combined antihypertensive drugs is given. Based on data from multicenter clinical trials, the article provides evidence of the benefits of dual and triple fixed drug combinations. Combinations of 1-adrenoreceptor antagonist bisoprolol and the dihydropyridine-type calcium channel blocker amlodipine are considered. The article highlights the advantages of each of the drugs, as well as their combination. It shows the benefits of a fixed combination of low
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Zhdan, V. М., V. G. Lebid, H. S. Кhaimenova, and G. A. Isheikina. "GOUT AND ARTERIAL HYPERTENSION: THERAPY PECULIARITIES." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 20, no. 1 (2020): 100–105. http://dx.doi.org/10.31718/2077-1096.20.1.100.

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The article highlights the issues on comorbidity between gout and hypertension. Emphasis is placed on the necessity in searching for a well-balanced approach toward the treatment this type of comorbidity. Gout is a major social and economic problem in the modern society that leads to a progressive physical incapability, limitation of professional activity, thus impairing the quality of life. Arterial hypertension occurs in patients with gout in 5 - 50% of cases, and in combination with components of metabolic syndrome its prevalence rises up to 80%. As a result, the development of hypertension
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7

Temnikova, E. A. "A new fixed combination of perindopril, indapamide and amlodipine. "Three in one" is the way to improve the results of arterial hypertension treatment." Systemic Hypertension 14, no. 2 (2017): 65–68. http://dx.doi.org/10.26442/sg29195.

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The management of patients with arterial hypertension is a difficult problem even if use the modern antihypertensive drugs. The reasons of the inadequate control to arterial pressure level during the treatment are different. The application fixed combinations of antihypertensive drugs improves the results of therapy, weigh with separate pathogenetic mechanisms of blood pressure increasing and the counterregulatory effects of the treatment each components of the combination. The use of fixed combinations significantly increases patient adherence to treatment. A new fixed triple combination of p
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8

Shehyan, G. G., A. A. Yalymov, A. M. Schikota, V. S. Zadionchenko, and S. I. Varentsov. "The telmisartan and amlodipine combination in the treatment of hypertension." Systemic Hypertension 11, no. 1 (2014): 64–72. http://dx.doi.org/10.26442/sg29014.

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The following review assesses socially significant disease - hypertension (AH) - and the problem of finding an effective antihypertensive therapy. Twynsta® drug (manufacturer Boehringer Ingelheim Pharma) - modern combined antihypertensive drug, which not only provides effective blood pressure control, but also due to the protective effect has been proved for all target organs improves the life expectancy of patients with hypertension. The clinical studies show that combination of telmisartan and amlodipine provides additional benefits in the treatment of patients with metabolic syndrome (by im
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9

Lebedev, P. A., A. A. Garanin, and E. V. Paranina. "Evolution of antihypertensive combined therapy: from depressin of academician A. L. Myasnikov to modern multi-component drugs." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 27, no. 1 (2021): 73–82. http://dx.doi.org/10.18705/1607-419x-2021-27-1-73-82.

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The article shows the historical background to the emergence and subsequent development of combined antihypertensive therapy from creation of a multi-component drug to modern fixed combinations as the most effective approach in the treatment of hypertension (HTN). The authors consider that Russian scientist therapist academician of the USSR Academy of medical Sciences A. L. Myasnikov, has priority in the development of fixed drug combination concept, created depressin powder. The development of pharmacology as a science and the achievements in pharmaceutical technologies contributed to the exp
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10

Ostroumova, O. D., O. V. Bondarets, I. I. Kopchenov, and T. F. Guseva. "From the choice of antihypertensive drug to the choice of fixed combinations of antihypertensive drugs: a paradigm shift." Systemic Hypertension 12, no. 4 (2015): 23–29. http://dx.doi.org/10.26442/sg29109.

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The article considers modern approaches to treatment of arterial hypertension. Emphasizes the need for combination antihypertensive therapy, mainly fixed combinations of antihypertensive drugs, patients with high and very high risk already at the start of treatment. Discusses the advantages of combinations of blockers of receptors of angiotensin II to diuretics and calcium antagonists, as well as clinical situations in which these combinations are a priority. Considered the evidence base, pharmacokinetics and clinical benefit of the representative of a class of blockers of receptors for angiot
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Dissertations / Theses on the topic "Modern antihypertensives drugs"

1

BOJIČOVÁ, Ljiljana. "Sociální dopady nemocí oběhové soustavy a možnosti moderní léčby hypertenze." Doctoral thesis, 2011. http://www.nusl.cz/ntk/nusl-52594.

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Mohammed, Mohammed A., Sayed C. El, and T. Marshall. "Patient and other factors influencing the prescribing of cardiovascular prevention therapy in the general practice setting with and without nurse assessment." 2012. http://hdl.handle.net/10454/6102.

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BACKGROUND: Although guidelines indicate when patients are eligible for antihypertensives and statins, little is known about whether general practitioners (GPs) follow this guidance. OBJECTIVE: To determine the factors influencing GPs decisions to prescribe cardiovascular prevention drugs. DESIGN OF STUDY: Secondary analysis of data collected on patients whose cardiovascular risk factors were measured as part of a controlled study comparing nurse-led risk assessment (four practices) with GP-led risk assessment (two practices). SETTING: Six general practices in the West Midlands, England. PATIE
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Book chapters on the topic "Modern antihypertensives drugs"

1

Burnier, Michel, Sverre Kjeldsen, Anthony Heagerty, and Bryan Williams. "Drug treatment of hypertension." In ESC CardioMed, edited by Bryan Williams. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0569.

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The prescription of antihypertensive drugs to achieve the recommended target blood pressures remains the main step of the management of hypertensive patients. Today, there is strong evidence from randomized controlled trials that antihypertensive drug classes proposed to treat hypertension are superior to placebo in reducing cardiovascular mortality and morbidity. In terms of cardiovascular protection, differences between drug classes exist but they are relatively modest. Indeed, the reduction of blood pressure per se remains the prominent mechanism whereby antihypertensive drugs provide cerebral, cardiac, renal, and vascular benefits. According to more recent guidelines, three drug classes are recommended as first-line therapy: blockers of the renin–angiotensin system, diuretics, and calcium antagonists. The use of beta blockers has been restricted to the treatment of hypertension associated with cardiac co-morbidities such as post-myocardial infarction or coronary heart disease. Many studies have demonstrated that drug classes can be combined successfully and nowadays, it is strongly recommended to use single pill combinations containing two or three antihypertensive drugs. This simplifies the treatment regimen, increases the efficacy, and promotes the long-term adherence and persistence, this latter being the major challenge of drug therapy for hypertension.
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2

Burnier, Michel, Sverre Kjeldsen, Anthony Heagerty, and Bryan Williams. "Drug treatment of hypertension." In ESC CardioMed, edited by Bryan Williams. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0569_update_001.

Full text
Abstract:
The prescription of antihypertensive drugs to achieve the recommended target blood pressures remains the main step of the management of hypertensive patients. Today, there is strong evidence from randomized controlled trials that antihypertensive drug classes proposed to treat hypertension are superior to placebo in reducing cardiovascular mortality and morbidity. In terms of cardiovascular protection, differences between drug classes exist but they are relatively modest. Indeed, the reduction of blood pressure per se remains the prominent mechanism whereby antihypertensive drugs provide cerebral, cardiac, renal, and vascular benefits. According to more recent guidelines, three drug classes are recommended as first-line therapy: blockers of the renin–angiotensin system, diuretics, and calcium antagonists. The use of beta blockers has been restricted to the treatment of hypertension associated with cardiac co-morbidities such as post-myocardial infarction or coronary heart disease. Many studies have demonstrated that drug classes can be combined successfully and nowadays, it is strongly recommended to use single pill combinations containing two or three antihypertensive drugs. This simplifies the treatment regimen, increases the efficacy, and promotes the long-term adherence and persistence, this latter being the major challenge of drug therapy for hypertension.
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Journal articles
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