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Journal articles on the topic 'Modern Therapeutics'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Kaffes, Arthur John. "Advances in modern enteroscopy therapeutics." Best Practice & Research Clinical Gastroenterology 26, no. 3 (2012): 235–46. http://dx.doi.org/10.1016/j.bpg.2012.03.011.

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2

Sar, Pratyusa. "Effectiveness of Bio-Drugs and Therapeutics in Modern Day Treatment." Journal of Pharmaceutical Research and Innovation 1, no. 1 (2021): 8–14. http://dx.doi.org/10.36647/jpri/01.01.a002.

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Modern medicine and procedure of treatment is important in the fields of emergencies and infectious disease in aid to cure. Biologics or bio-drugs are generally defined as a wide range of products that includes various vaccines and gene therapy .The present research tries to evaluate the effectiveness of Bio-drugs in the modern medical science and the functions of therapeutics in the modern day treatment. Qualitative and secondary data collection method has been used in order to evaluate and analyse the present research. Keyword : — bio-drugs, therapeutics, ADR, therapeutic protein, somatic ce

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Haider, Saher Binte, Ramsha Afaque, Sadia Ali Vohra, et al. "Monoclonal antibodies: Revolutionary pharmaceuticals in modern therapeutics." El Mednifico Journal 1, no. 1 (2013): 15. http://dx.doi.org/10.18035/emj.v1i1.16.

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Basak, Gourab, Rupam Malakar, Ambika Sharma, Sanjay K. Bharti, and Barkha Sharma. "Medicinal Herbs – Boon for Modern Veterinary Therapeutics." International Journal of Bio-resource and Stress Management 11, no. 2 (2020): 188–94. http://dx.doi.org/10.23910/ijbsm/2020.11.2.2081b.

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5

Harder, Jürgen. "Antimicrobial peptides: ancient molecules as modern therapeutics?" Expert Review of Dermatology 3, no. 1 (2008): 1–5. http://dx.doi.org/10.1586/17469872.3.1.1.

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6

Adam, Dieter. "MODERN CEPHALOSPORINS AS THERAPEUTICS FOR OTITIS MEDIA." Infectious Diseases in Clinical Practice 7, Supplement 2 (1998): S96. http://dx.doi.org/10.1097/00019048-199808002-00008.

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7

Ibrahim Ali Mahdi Al-Qashanin. "Expanding the Horizons of mRNA Therapeutics: Applications Beyond Vaccines in Modern Medicine – A Systematic Review." Power System Technology 48, no. 4 (2024): 196–205. https://doi.org/10.52783/pst.990.

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mRNA therapeutics, once primarily confined to the realm of vaccine development, have emerged as a versatile platform with potential applications across numerous fields of medicine. This systematic review explores the expanding role of mRNA therapeutics beyond vaccines, focusing on key advancements in cancer therapy, treatment of genetic disorders, infectious disease management, cardiovascular disease, and autoimmune conditions. By evaluating recent preclinical and clinical research, we assess the unique mechanisms, therapeutic potential, and delivery challenges associated with these applicatio

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Hidangmayum, Narmada, Noushad Yashan, Prafulla Udayan Shah, Anmol Anmol, Janardhan Namdeo Nehul, and Harsh Namdev Bhor. "Unveiling the Healing Power of Traditional Medicine: Bridging Ancient Practices with Modern Therapeutics." Acta Traditional Medicine 3, no. 2 (2024): 4–8. https://doi.org/10.51470/atm.2024.3.2.04.

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Traditional medicine has been an integral part of human health and well-being for centuries. Its rich history, rooted in cultural and regional diversity, offers a reservoir of therapeutic practices and remedies that modern medicine continues to explore. This review article aims to elucidate the healing potential of traditional medicine by examining its historical significance, contemporary relevance, and the scientific validation of its efficacy, the article delves into the symbiotic relationship between traditional and modern therapeutics, highlighting opportunities and challenges in integrat

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Mitra, Jyotsna Bhatt, Veerendra K. Sharma, Mukesh Kumar, and Archana Mukherjee. "Antimicrobial Peptides: Vestiges of Past or Modern Therapeutics?" Mini-Reviews in Medicinal Chemistry 20, no. 3 (2020): 183–95. http://dx.doi.org/10.2174/1389557519666191125121407.

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The ubiquitous occurrence of Antimicrobial Peptides (AMPs) in all domains of life emphasizes their crucial role as ancient mediators of host defense. Despite their antiquity and prolonged history of exposure to pathogens, endogenous AMPs continue to serve as effective antibiotics. An "evolutionary arms race" between host and pathogen resulted in structural diversity of AMPs, leading these molecules to retain activity against a wide range of pathogens, including antibiotic-resistant microbes. As the menace of antibiotic resistance continues to render most antibiotics ineffective against pathoge

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10

Wright, Bernice. "Forging a modern generation of polyphenol-based therapeutics." British Journal of Pharmacology 169, no. 4 (2013): 844–47. http://dx.doi.org/10.1111/bph.12195.

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Pandey, Vinay Kumar, Vinayak Majhi, Sudip Paul, and Shruti Jain. "Gamifying Therapy: A New Approach to Modern Therapeutics." Procedia Computer Science 235 (2024): 2043–55. http://dx.doi.org/10.1016/j.procs.2024.04.194.

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12

Singleton, Mark. "Suggestive Therapeutics: New Thought's Relationship to Modern Yoga." Asian Medicine 3, no. 1 (2007): 64–84. http://dx.doi.org/10.1163/157342107x207218.

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Modern, transnational yoga in the early twentieth century often defined itself in terms and ideologies borrowed from the popular current of esoteric American Protestantism known as New Thought. Like its forebear Transcendentalism, the New Thought movement was itself receptive to Indian ideas, albeit radically reworked to fit the doctrine of divinised self-hood and cosmic healing that it purveyed. Such adaptations were dialectically reabsorbed by exponents of the yoga renaissance, in a mutually reinforcing, cross-cultural rewriting of the theoretical bases and practices of yoga. New Thought pro

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13

Shende, Pravin, and Chandan Mallick. "Nanonutraceuticals: A way towards modern therapeutics in healthcare." Journal of Drug Delivery Science and Technology 58 (August 2020): 101838. http://dx.doi.org/10.1016/j.jddst.2020.101838.

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14

Da-Yong Lu, Hong-Ying Wu, Bin Xu, and Ting-Ren Lu. "Neurobiology for human suicide." International Journal of Science and Research Archive 2, no. 2 (2021): 120–25. http://dx.doi.org/10.30574/ijsra.2021.2.2.0056.

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In the future, suicide risk prediction and management should be transformed from psychiatrist’s judgment (mental illness-like symptoms) into modern technique-guided diagnostics and target drug therapeutics in larger clinical settings. To embrace modern scientific and technological advances, a number of unique diagnostic and therapeutic approaches must be established. This Article provides some important ideas and mechanisms proposed by translational programs.

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15

Bogomolova, E. G., P. M. Kopeykin, and A. A. Tagaev. "Genetic engineering approaches to the development of modern therapeutics." Medical academic journal 20, no. 3 (2020): 49–60. http://dx.doi.org/10.17816/maj34092.

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The classic approach to production of protein-based therapeutics is their isolation from natural sources. This approach was associated with a number of difficulties, such as collecting the primary material from natural sources, isolating and purifying the protein, and its standardizing. With the development of recombinant DNA technology, itbecame possible to obtain large quantities of protein preparations lacking any contaminations. Human insulin produced using recombinant DNA technology is the first commercial therapeutic obtained by this way. Due to the rapid development of genetic engineeri

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Stortecky, Stefan, and Thomas M. Suter. "Insights into cardiovascular side-effects of modern anticancer therapeutics." Current Opinion in Oncology 22, no. 4 (2010): 312–17. http://dx.doi.org/10.1097/cco.0b013e32833ab6f1.

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17

Gil’deeva, G. N., and V. I. Yurkov. "Microemulsions as Potential Bases for Formulating Modern Transdermal Therapeutics." Pharmaceutical Chemistry Journal 52, no. 6 (2018): 550–52. http://dx.doi.org/10.1007/s11094-018-1858-6.

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18

Kalafatakis, Konstantinos. "The translational aspects of glucocorticoid biorhythmicity in modern therapeutics." Review of Clinical Pharmacology and Pharmacokinetics - International Edition 38, Sup2 (2024): 19–21. http://dx.doi.org/10.61873/xeyd8146.

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Glucocorticoids are a class of steroid hormones, vital for mammalian life. They have a plethora of biological effects, mainly supporting metabolic, cognitive, and immunological functions. The pharmacological use of glucocorticoids makes them one of the most frequently prescribed drugs across all continents, and in all types of forms. Nevertheless, a number of serious adverse effects accompany the prolonged treatment with high doses of glucocorticoids. Research developments over the last 20 years have gradually reshaped the way we think about glucocorticoid-based therapeu¬tics. Aside their circ

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Nicolaescu, Oana Elena, Ionela Belu, Andreea Gabriela Mocanu, et al. "Cyclodextrins: Enhancing Drug Delivery, Solubility and Bioavailability for Modern Therapeutics." Pharmaceutics 17, no. 3 (2025): 288. https://doi.org/10.3390/pharmaceutics17030288.

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Cyclodextrins (CDs) have revolutionized the pharmaceutical industry with their ability to enhance the stability, solubility, and bioavailability of a wide range of active substances. These cyclic oligosaccharides, with a unique hydrophilic exterior and hydrophobic cavity, form inclusion complexes with poorly soluble drugs, improving their pharmacokinetic profiles and therapeutic efficacy. This review explores the multifaceted roles of cyclodextrins in pharmaceutical formulations, ranging from oral, ophthalmic, parenteral, and topical applications to their emerging use in targeted therapies, ge

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MANI, DAYA N., SEEMA SHUKLA, and YOGENDRA N. SHUKLA. "Medicinal plant-derived therapeutics for treatment of neoplasms in modern and traditional systems of medicine." Journal of Medicinal and Aromatic Plant Sciences 42, no. 2020 (2020): 1–29. http://dx.doi.org/10.62029/jmaps.v42i1.mani.

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Tian, Yuwei, and Brandon T. Ruotolo. "The growing role of structural mass spectrometry in the discovery and development of therapeutic antibodies." Analyst 143, no. 11 (2018): 2459–68. http://dx.doi.org/10.1039/c8an00295a.

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The comprehensive structural characterization of therapeutic antibodies is of critical importance for the successful discovery and development of such biopharmaceuticals, yet poses many challenges to modern measurement science. Here, we review the current state-of-the-art mass spectrometry technologies focusing on the characterization of antibody-based therapeutics.

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Ratay, Michelle L., Elena Bellotti, Riccardo Gottardi, and Steven R. Little. "Ocular Therapeutics: Modern Therapeutic Approaches for Noninfectious Ocular Diseases Involving Inflammation (Adv. Healthcare Mater. 23/2017)." Advanced Healthcare Materials 6, no. 23 (2017): 1770116. http://dx.doi.org/10.1002/adhm.201770116.

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23

Sinha, Priyam, Shruti Srivastava, Nidhi Mishra, and Narayan Prasad Yadav. "New Perspectives on Antiacne Plant Drugs: Contribution to Modern Therapeutics." BioMed Research International 2014 (2014): 1–19. http://dx.doi.org/10.1155/2014/301304.

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Acne is a common but serious skin disease, which affects approximately 80% adolescents and young adults in 11–30 age group. 42.5% of men and 50.9% of women continue to suffer from this disease into their twenties. Bacterial resistance is now at the alarming stage due to the irrational use of antibiotics. Hence, search for new lead molecule/bioactive and rational delivery of the existing drug (for better therapeutic effect) to the site of action is the need of the hour. Plants and plant-derived products have been an integral part of health care system since time immemorial. Therefore, plants th

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Yamoah, James. "EXPLORING THE PHARMACOLOGICAL POTENTIAL OF MEDICINAL PLANTS IN MODERN THERAPEUTICS." International Journal of Pharmaceutical Science and Medicine 2, no. 4 (2024): 82–88. https://doi.org/10.70199/ijpsm.2.3.82-88.

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25

BÁLint, Geza P., Walter F. Kean, and W. Watson Buchanan. "Sir William Osler (1849-1919): His Opinion of Modern Therapeutics." Scottish Medical Journal 51, no. 1 (2006): 51–54. http://dx.doi.org/10.1258/rsmsmj.51.1.51.

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26

Ellis, Terry D., and Gammon M. Earhart. "Digital Therapeutics in Parkinson’s Disease: Practical Applications and Future Potential." Journal of Parkinson's Disease 11, s1 (2021): S95—S101. http://dx.doi.org/10.3233/jpd-202407.

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Digital therapeutics, treatments delivered remotely and enabled by modern technology, facilitate the provision of personalized, evidence-based, interdisciplinary interventions to manage the complexities associated with Parkinson’s disease. In the context of the COVID-19 pandemic, the need for digital therapeutics has arguably never been greater. However, despite new advances in technology and a heightened interest due to the pandemic, digital therapeutics remain underdeveloped and underutilized. In this paper, we briefly review practical applications and emerging advances in digital therapeuti

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27

Ganguly, Priyanka, Somnath Dutta, Nirmal Debnath, and Krishnashri Jana. "CONCEPT OF MEDICINAL LEECH THERAPY OR HIRUDOTHERAPY IN AYURVEDIC AND MODERN ASPECT." International Ayurvedic Medical Journal 13, no. 02 (2025): 450–59. https://doi.org/10.46607/iamj2313022025.

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Medicinal Leech therapy or Hirudotherapy is coined in Ayurveda as Jalaukavacharana, a conventional bloodletting treatment illustrated extensively in vintage manuscripts like Sushruta Samhita and Charaka Samhita. This therapy involves harnessing medicinal leeches to draw out impure blood, which provides the equilibrium condition of doshas by balancing them and enhancing the microcirculation. With its roots or original foundation in ancient medicine, Hirudotherapy has found renewed relevance in modern therapeutics for managing conditions like venous insufficiency, osteoarthritis, and chronic wou

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Sakai, Daisuke, Jordy Schol, and Masahiko Watanabe. "Clinical Development of Regenerative Medicine Targeted for Intervertebral Disc Disease." Medicina 58, no. 2 (2022): 267. http://dx.doi.org/10.3390/medicina58020267.

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Low back pain is critical health, social, and economic issue in modern societies. This disease is often associated with intervertebral disc degeneration; however, contemporary treatments are unable to target this underlying pathology to alleviate the pain symptoms. Cell therapy offers a promising novel therapeutic that, in theory, should be able to reduce low back pain through mitigating the degenerative disc environment. With the clinical development of cell therapeutics ongoing, this review aims to summarize reporting on the different clinical trials and assess the different regenerative str

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Batta, Angelika, Raj Khirasaria, and Vikramjit Singh. "Exploring digital therapeutics: The next paradigm of modern health-care industry." Perspectives in Clinical Research 11, no. 2 (2020): 54. http://dx.doi.org/10.4103/picr.picr_89_19.

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30

Bhat, Pravin M. "A REVIEW ON KRIYAKALPA: THE MODERN APPROACH TO AYURVEDIC OCULAR THERAPEUTICS." International Journal of Research in Ayurveda & Pharmacy 7, no. 5 (2016): 12–16. http://dx.doi.org/10.7897/2277-4343.075186.

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31

Temel, Jennifer S., Alice T. Shaw, and Joseph A. Greer. "Challenge of Prognostic Uncertainty in the Modern Era of Cancer Therapeutics." Journal of Clinical Oncology 34, no. 30 (2016): 3605–8. http://dx.doi.org/10.1200/jco.2016.67.8573.

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32

Durgesh, Gavande* Anjali Wankhade Vivek Paithankar. "Chemical Insights and Therapeutics Potential of Fagonia Arabica in Modern Medicines." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 2006–16. https://doi.org/10.5281/zenodo.15231353.

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Plants are itself a chemical laboratory<strong> </strong>which synthesize a million of compounds per second Throughout their life span, some of them are essential for their life cycle and remaining are stored as the secondary metabolites like alkaloids, glycoside, flavonoids, resins etc… for the various secondary functions. This review elaborates various biological compounds, their chemical characterization and pharmacological characterizations and their correlational responses with the specific chemical compounds. Fagonia arabica is one of the most potent and effective herbal remedies

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Mertens, Lea J., and Katrin H. Preller. "Classical Psychedelics as Therapeutics in Psychiatry – Current Clinical Evidence and Potential Therapeutic Mechanisms in Substance Use and Mood Disorders." Pharmacopsychiatry 54, no. 04 (2021): 176–90. http://dx.doi.org/10.1055/a-1341-1907.

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AbstractClassical psychedelics, primarily psilocybin and lysergic acid diethylamide (LSD), have been used and extensively studied in Western medicine as part of substance-assisted psychotherapy in the 1950s and 1960s. Modern clinical research is currently gaining momentum and provides new evidence for the safety and efficacy of classical psychedelics (primarily psilocybin, but also LSD and ayahuasca) in the treatment of different psychiatric conditions, including substance use and mood disorders.In this review article, we outline common pathological mechanisms of substance use disorders (SUD)

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34

Budde, Priya Prakash, Elizabeth H. Williams, and Tom Misteli. "Cell biology: At the center of modern biomedicine." Journal of Cell Biology 199, no. 1 (2012): 7–8. http://dx.doi.org/10.1083/jcb.201209062.

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How does basic cell biology contribute to biomedicine? A new series of Features in JCB provides a cross section of compelling examples of how basic cell biology findings can lead to therapeutics. These articles highlight the fruitful, essential, and increasingly prominent bridge that exists between cell biology and the clinic.

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Maliha Mirza, Haniya Jabeen, and Ayesha Fatima. "Artificial Intelligence in Digital Therapeutics for Optimized Healthcare." Journal of Pharma Insights and Research 3, no. 2 (2025): 346–57. https://doi.org/10.69613/g5mbda64.

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Digital therapeutics (DTx) powered by artificial intelligence are reshaping modern healthcare by innovative ways of disease prevention, management, and treatment. The usage of machine learning, natural language processing, and computer vision enables DTx platforms to process patient data in real-time, predict health trajectories, and deliver personalized interventions. These intelligent systems optimize therapeutic efficacy based on individual patient responses while monitoring adherence and progress metrics to enhance clinical outcomes. In mental health applications, AI algorithms evaluate be

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36

Florinskiy, D. B., and P. A. Zharkov. "Modern approaches in hemophilia therapy." Pediatric Hematology/Oncology and Immunopathology 19, no. 3 (2020): 131–38. http://dx.doi.org/10.24287/1726-1708-2020-19-3-131-138.

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For 60 years the “gold standard” of hemophilia treatment has been the use of concentrates factors. In recent years, there has been a rapid development of therapeutics. Several extended half-life concentrates have been introduced into clinical practice, as well as a non – factorial type of therapy-a bispecific antibody mimicking activated factor VIII. Encouraging results in clinical trials show the use of antibodies to tissue factor pathway inhibitor, small interfering RNA to antithrombin and gene therapy. The advantages of new treatment methods are a reduction in the frequency of intravenous i

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Keith, W. Nicol, Alan Bilsland, T. R. Jeffry Evans, and Rosalind M. Glasspool. "Telomerase-directed molecular therapeutics." Expert Reviews in Molecular Medicine 4, no. 10 (2002): 1–25. http://dx.doi.org/10.1017/s1462399402004507.

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The management of malignant disease remains one of the most challenging areas of modern medicine. The lifetime risk of developing cancer in the western world is estimated to be as high as 1 in 3. Traditionally, surgery, chemotherapy and radiotherapy have been the primary choice of treatment for patients with malignant tumours. Despite advances in the use and development of conventional cytotoxic agents, the cure rate remains disappointing in most patients with advanced disease of the common solid tumours. Consequently, the development of novel anti-cancer therapies is a high priority in cancer

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38

Mallis, Panagiotis, Efstathios Michalopoulos, and Catherine Stavropoulos-Giokas. "Modern Approaches in Cardiovascular Disease Therapeutics: From Molecular Genetics to Tissue Engineering." Bioengineering 8, no. 11 (2021): 174. http://dx.doi.org/10.3390/bioengineering8110174.

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Cardiovascular disease (CVD) currently represents one of the leading causes of death worldwide. It is estimated that more than 17.9 million people die each year due to CVD manifestations. Often, occlusion or stenosis of the vascular network occurs, either in large- or small-diameter blood vessels. Moreover, the obstruction of small vessels such as the coronary arteries may be related to more pronounced events, which can be life-threatening. The gold standard procedure utilizes the transplantation of secondary vessels or the use of synthetic vascular grafts. However, significant adverse reactio

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Choudhary, Shazia, Sheeba Murad, Sana Gul, et al. "Small Interfering RNA- Modern Approach for Intervening Pathological Conditions." NUST Journal of Natural Sciences 2, no. 2 (2021): 16–19. http://dx.doi.org/10.53992/njns.v2i2.37.

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RNA interference (RNAi) refers to the inhibition of gene expression by small double-stranded RNA molecules. This technology can prove to be a breakthrough biological discovery of the decade as it has the potential to revolutionize the field of therapeutics. RNA interference (RNAi) through small interfering RNA (siRNA) is currently being evaluated for its efficacy to be used in therapeutics as well as prophylactic strategies. Many studies are being conducted across the globe to optimize the siRNA delivery systems (in terms of safe, stable and efficient delivery) in various disorders. There are

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40

Koç, Dilara. "Nanotechnology in Modern Medicine: A Revolutionary Approach to Targeted Drug Delivery." Journal of Science, Technology and Engineering Research 1, no. 1 (2024): 16–31. https://doi.org/10.64206/98cezx78.

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Nanotechnology has revolutionized modern medicine by enabling highly precise and efficient targeted drug delivery systems. This paper explores the recent advancements in Nano carrier design, including liposomes, dendrimers, polymeric nanoparticles, and metallic nanostructures, which facilitate controlled release and improved bioavailability of therapeutic agents. By focusing on targeted delivery, these nanotechnologies minimize systemic toxicity and enhance treatment efficacy, particularly in cancer, infectious diseases, and chronic conditions. The review also discusses the challenges related

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Sakshi, Nagrikar*1 Keshav Bondre1 Sadhna Gautam2 Bhushan Gandhare2. "A Review on Leucas Indica: A Promising Medicinal Herb for Modern Therapeutics." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3575–90. https://doi.org/10.5281/zenodo.15479470.

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<em>Leucas indica</em> (Lamiaceae), a widely distributed medicinal plant in tropical and subtropical regions, holds significant traditional and ethnomedicinal importance. This review provides a comprehensive overview of <em>L. indica</em>, covering its botanical profile, detailed morphological description, and geographical distribution. Traditionally, various parts of the plant have been utilized to manage ailments such as fever, inflammation, infections, and respiratory disorders. Phytochemical investigations reveal the presence of flavonoids, terpenoids, phenolics, alkaloids, and other bioac

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Nerkar, Amit G. "Molecular medicine: Pioneering the future of healthcare." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 2 (2024): 32–33. http://dx.doi.org/10.18231/j.ctppc.2024.010.

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Modern Medicine academic qualifications include degrees earned in Allopathy, Medicine, Pharmacy & Pharmaceutical Sciences, Dental Sciences, Nursing and Veterinary Sciences only. However Veterinary sciences are devoid of practice at human level and thus the doctorates (PhDs) holders and pursuing Molecular Medicine should be involved in active diagnostics, therapeutics, and clinical therapeutics.

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Shastri, Sravanthi, Bhaswati Chatterjee, and Suman S. Thakur. "Achievements in Cancer Research and its Therapeutics in Hundred Years." Current Topics in Medicinal Chemistry 19, no. 17 (2019): 1545–62. http://dx.doi.org/10.2174/1568026619666190730093034.

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Cancer research has progressed leaps and bounds over the years. This review is a brief overview of the cancer research, milestone achievements and therapeutic studies on it over the one hundred ten years which would give us an insight into how far we have come to understand and combat this fatal disease leading to millions of deaths worldwide. Modern biology has proved that cancer is a very complex disease as still we do not know precisely how it triggers. It involves several factors such as protooncogene, oncogene, kinase, tumor suppressor gene, growth factor, signalling cascade, micro RNA, i

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44

Danao, Kishor R., Pooja M. Malghade, Debarshi Kar Mahapatra, Meha N. Motiwala, and Ujwala N. Mahajan. "Progressive Insights into the Pharmacological Importance of Isoquinoline Derivatives in Modern Therapeutics." International Journal of Current Research and Review 13, no. 04 (2021): 83–90. http://dx.doi.org/10.31782/ijcrr.2021.13421.

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45

Lakhanpal, Amit, and Ernest Brahn. "A perspective on modern advances for COVID-19 (SARS-CoV-2) therapeutics." European Journal of Rheumatology 7, Supp2 (2020): S102—S106. http://dx.doi.org/10.5152/eurjrheum.2020.2065.

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46

Khatri, Savita, Manish Kumar, Neetu Phougat, Renu Chaudhary, and Anil Kumar Chhillar. "Perspectives on Phytochemicals as Antibacterial Agents: An Outstanding Contribution to Modern Therapeutics." Mini-Reviews in Medicinal Chemistry 16, no. 4 (2016): 290–308. http://dx.doi.org/10.2174/138955751604160201150438.

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47

Emi, Maria C. Baijo* Helga Rose Sahla Ashraf Lincy George. "Diuretics in Hypertension Management: Mechanistic Insights and Clinical Implications for Modern Therapeutics." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 458–65. https://doi.org/10.5281/zenodo.15334698.

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Diuretics remain a cornerstone in the management of hypertension and various fluid overload conditions, including heart failure, nephrotic syndrome, and liver cirrhosis. This review examines their pharmacological mechanisms, therapeutic applications, and evolving clinical positioning across a range of disease. Over the decades, hypertension guidelines have shifted in their preference for diuretics versus newer antihypertensive agents, often driven by concerns about metabolic side effects and evidence from landmark clinical trials. Despite these fluctuations, thiazide diuretics—especially

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Aprotosoaie, Ana Clara, Alexandru-Dan Costache, and Irina-Iuliana Costache. "Therapeutic Strategies and Chemoprevention of Atherosclerosis: What Do We Know and Where Do We Go?" Pharmaceutics 14, no. 4 (2022): 722. http://dx.doi.org/10.3390/pharmaceutics14040722.

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Despite progress in understanding the pathogenesis of atherosclerosis, the development of effective therapeutic strategies is a challenging task that requires more research to attain its full potential. This review discusses current pharmacotherapy in atherosclerosis and explores the potential of some important emerging therapies (antibody-based therapeutics, cytokine-targeting therapy, antisense oligonucleotides, photodynamic therapy and theranostics) in terms of clinical translation. A chemopreventive approach based on modern research of plant-derived products is also presented. Future persp

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49

Rydberg, Andreas. "Johann Georg Zimmermann’s Therapeutics of Solitude in the German Enlightenment." Emotions: History, Culture, Society 5, no. 2 (2021): 259–78. http://dx.doi.org/10.1163/2208522x-02010130.

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Abstract This essay charts the German eighteenth-century physician and writer Johann Georg Zimmermann’s monumental work on solitude. The essay draws on but also challenges recent historiography on two counts. First, it situates Zimmermann’s discourse on solitude in the context of the early modern cultura animi tradition, in which philosophy provided a cure for a soul perceived as diseased and perturbed by passion and desire. Placed in this context, solitude comes into view not primarily as a passive state of rest and tranquillity connected to the rural life, but as active, therapeutic and exer

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Sharma, Alka, Sudhanshu Kumar Jha, and Vitthal G. Huddar. "Integrative role of Ayurvedic phytochemicals in cancer treatment: Targeting signaling pathways, boosting chemosensitivity, and utilizing traditional therapeutics." Ayush Journal of Integrative Oncology 2, no. 2 (2025): 77–85. https://doi.org/10.4103/ajio.ajio_18_25.

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Abstract Cancer remains a leading cause of mortality, necessitating innovative approaches that integrate phytochemicals, modern oncology, and Ayurvedic medicine. This review explores key signaling pathways targeted by bioactive compounds, including mitogen-activated protein kinase, PI3K/Akt, and JAK/STAT, highlighting tumor suppression and apoptosis-inducing mechanisms. Phytochemicals such as curcumin, anthocyanins, and stilbene-based derivatives exhibit significant anticancer potential by modulating oxidative stress, angiogenesis, and apoptosis. Ayurvedic formulations such as Triphala, Chyava

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