Academic literature on the topic 'Modified herpes virus'

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Journal articles on the topic "Modified herpes virus"

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Rybalko, S., N. Nesterova, S. Diadiun, et al. "Therapeutical effect of modified adamantane copolymer compounds: study of molecular mechanisms." Acta Biochimica Polonica 48, no. 1 (2001): 241–49. http://dx.doi.org/10.18388/abp.2001_5132.

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Copolymers of N-polyvinylpyrrolidone-acrylic acid (AB-1) and adamantane derivatives are known to possess marked antiviral activity in in vitro and in ovo models. Among the constructed preparations of AB-1 modified by adamantane derivatives some, especially AB-4 (modified by deitiforin), were found to show more extended antiviral activity and to inhibit markedly virus reproduction in susceptible permissive cell cultures and chicken embryos. In AB-4 treated cells and allantoic sacs, virus titers (influenza virus, herpes virus, and HIV) and virus antigen concentration were decreased. On the other
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Kibuule, Grace N., Jay M. Truitt, and Michelle Tarbox. "Modified Tzanck Smear to Evaluate for Herpes Simplex Virus." Journal of Drugs in Dermatology 22, no. 12 (2023): e38-e39. http://dx.doi.org/10.36849/jdd.4763.

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Nandi, S., Manoj Kumar, M. Manohar, and R. S. Chauhan. "Bovine herpes virus infections in cattle." Animal Health Research Reviews 10, no. 1 (2009): 85–98. http://dx.doi.org/10.1017/s1466252309990028.

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AbstractBovine herpes virus 1 (BHV-1) is primarily associated with clinical syndromes such as rhinotracheitis, pustular vulvovaginitis and balanoposthitis, abortion, infertility, conjunctivitis and encephalitis in bovine species. The main sources of infection are the nasal exudates and the respiratory droplets, genital secretions, semen, fetal fluids and tissues. The BHV-1 virus can become latent following a primary infection with a field isolate or vaccination with an attenuated strain. The viral genomic DNA has been demonstrated in the sensory ganglia of the trigeminal nerve in infectious bo
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Samson, Kurt. "Modified Herpes Virus Shows Promise in High-Grade Pediatric Glioma." Oncology Times 43, no. 11 (2021): 45. http://dx.doi.org/10.1097/01.cot.0000754732.62026.79.

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Chen, Liting, Chen Xu, Hainan Xu, et al. "RVG29-modified oncolytic herpes simplex virus for intracranial tumor treatment." Nano Today 61 (April 2025): 102573. https://doi.org/10.1016/j.nantod.2024.102573.

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Bultmann, Hermann, James S. Busse, and Curtis R. Brandt. "Modified FGF4 Signal Peptide Inhibits Entry of Herpes Simplex Virus Type 1." Journal of Virology 75, no. 6 (2001): 2634–45. http://dx.doi.org/10.1128/jvi.75.6.2634-2645.2001.

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ABSTRACT Entry of herpes simplex virus type 1 (HSV-1) into host cells occurs through fusion of the viral envelope with the plasma membrane and involves complex and poorly understood interactions between several viral and cellular proteins. One strategy for dissecting the function of this fusion machine is through the use of specific inhibitors. We identified a peptide with antiviral activity that blocks HSV-1 infection at the entry stage and during cell-to-cell spreading. This peptide (called EB for “entry blocker”) consists of the FGF4 signal sequence with an RRKK tetramer at the amino termin
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Jones, Samuel T., Valeria Cagno, Matej Janeček, et al. "Modified cyclodextrins as broad-spectrum antivirals." Science Advances 6, no. 5 (2020): eaax9318. http://dx.doi.org/10.1126/sciadv.aax9318.

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Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal molecules described to date are cytotoxic. We recently developed nontoxic, broad-spectrum virucidal gold nanoparticles. Here, we develop further the concept and describe cyclodextrins, modified with mercaptoundecane sulfonic acids, to mimic heparan sulfates and to provide the key nontoxic virucidal action. We show that the resulting macromolecules are broad-spectrum, biocompatible, and virucidal at micromol
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Barton, S. E., P. E. Munday, and R. J. Patel. "Asymptomatic shedding of herpes simplex virus from the genital tract: uncertainty and its consequences for patient management." International Journal of STD & AIDS 7, no. 4 (1996): 229–32. http://dx.doi.org/10.1258/0956462961917799.

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A frequent component of the management of patients with genital herpes concerns the possibility of asymptomatic shedding and potential sexual transmission of the virus. Approaches intended to provide supportive counselling and reassurance of patients about these issues need now to be modified in the light of increasing data of the frequency of asymptomatic detection of virus and the effects of antiviral therapy on this phenomenon. Further studies to delineate the relationship between asymptomatic detection of HSV in the genital tract and the mechanism of sexual transmission of this virus need
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Zahornyi, M. M., O. M. Lavrynenko, O. Yu Pavlenko, et al. "The antiviral activity of cerium and lanthanum nanooxides modified with silver." Himia, Fizika ta Tehnologia Poverhni 14, no. 2 (2023): 262–72. http://dx.doi.org/10.15407/hftp14.02.262.

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Today, the antiviral activity of oxide nanomaterials can be used in the fight against the viral disease COVID-19. It is thought that Ag nanoparticles may bind to the surface glycoprotein of the virus and interfere with the virus’s interaction with epithelial cells, and inhibit virus reproduction by releasing silver ions in the cell. The viruses’ inhibition with RNA (ribonucleic acid) and DNA (deoxyribonucleic acid) genomes by oxide nanocomposites action was presented. In this research, the surface structure of doped CeO2 (La2O3) was studied by nitrogen adsorption-desorption based on BET method
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Liu, XueQiao, Eeva Broberg, Daisuke Watanabe, Timothy Dudek, Neal DeLuca, and David M. Knipe. "Genetic engineering of a modified herpes simplex virus 1 vaccine vector." Vaccine 27, no. 21 (2009): 2760–67. http://dx.doi.org/10.1016/j.vaccine.2009.03.003.

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Dissertations / Theses on the topic "Modified herpes virus"

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Hu, Jennifer Cho Chun. "The biological and cytotoxic effects of a genetically modified herpes simplex virus 1 and its potential application in clinical oncology." Thesis, Imperial College London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428744.

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Danileyko, S., Нiна Володимирiвна Мальована, Нина Владимировна Малеванная, and Nina Volodymyrivna Malovana. "A new class of cancer-killing viruses." Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/77974.

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T-VEC (Talimogene laherparepvec) is a local immunotherapy that contains a modified herpes virus with which a skin cancer can be cured. The invention of T-VEC can be called a breakthrough in medicine because it saves the lives of people who have inoperable stages III and IV of melanoma.
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Bennour, Emad. "Impact du protocole de transfert par voie rétrovirale du gène de l'enzyme thymidine kinase du virus Herpès Simplex sur le métabolisme protéique et la sensibilité au Ganciclovir de lymphocytes T génétiquement modifiés." Besançon, 2009. http://www.theses.fr/2009BESA0008.

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L'administration de Ganciclovir permet de contrôler l'alloréactivité de cellules T génétiquement modifiées (CGM) par le transfert ex vivo du gène de la thymidine kinase du virus Herpès Simplex (HSV-TK). Une limitation à cette approche est liée à la présence d'une forme inactive de ce gène résultant d'un épissage alternatif. Afin de surmonter cette limitation, notre équipe a développé une forme corrigée (cHSV-TK) fusionnée avec la forme tronquée du CD34 (tCD34) permettant un tri immunomagnétique des CGM. Nous montrons dans la première partie de cette thèse que malgré cette correction, des CGM C
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Books on the topic "Modified herpes virus"

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Biloshytsky, Vadym, and Roman Cregg. Pioneering use of gene therapy for pain. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0083.

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The landmark paper discussed in this chapter is ‘Gene therapy for pain: Results of a Phase I clinical trial’, published by Fink et al. in 2011. In this study, the first of its kind, researchers studied the efficacy and safety of a modified herpes simplex virus (HSV) vector used to deliver PENK, which encodes proenkephalin, which is cleaved into the enkephalin peptides Met-enkephalin and Leu-enkephalin, which induce analgesia by acting on opioid receptors. The development of the HSV vector was based in part on results studies in which adenovirus, adeno-associated virus, or non-viral vectors wer
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Swanepoel, R., and J. T. Paweska. Rift Valley fever. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0043.

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Rift Valley fever (RVF) is an acute disease of domestic ruminants in mainland Africa and Madagascar, caused by a mosquito borne virus and characterized by necrotic hepatitis and a haemorrhagic state. Large outbreaks of the disease in sheep, cattle and goats occur at irregular intervals of several years when exceptionally heavy rains favour the breeding of the mosquito vectors, and are distinguished by heavy mortality among newborn animals and abortion in pregnant animals. Humans become infected from contact with tissues of infected animals or from mosquito bite, and usually develop mild to mod
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Book chapters on the topic "Modified herpes virus"

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Karabin, Jerry M., and Lawrence A. Wilson. "Mechanism of “Modified-Self” Induced Anti-Herpes Simplex Virus (HSV) Antibody Unresponsiveness." In Viruses, Immunity, and Immunodeficiency. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2185-9_21.

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Conference papers on the topic "Modified herpes virus"

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Tawa, Keiko. "Sensitive Detection of Marker Proteins by the Enhanced Fluorescence Technique with a Plasmonic Chip." In Conference on Lasers and Electro-Optics/Pacific Rim. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleopr.2022.ctuw1_02.

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Plasmonic chip with a wavelength-size periodic structure can provide the enhanced electric field on the chip surface and therefore, in the fluorescence detection and imaging, the target molecule was sensitively detected with the sandwich immunoassay by the larger fluorescence signal. Here, the hole array-type and Bull's eye-type patterns were used for target detection of S-protein and single exosome, respectively. The capture interface was prepared for suppressing the nonspecific adsorption of labeled-antibody and detection antibody was also considered. The fluorescence was measured with an an
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Luche, DD. "SARS-COV-2 NT-CHIP, A NOVEL FUNCTIONAL MULTIPLEX IMMUNOASSAY FOR SARS-COV-2 EVALUATION OF HUMORAL RESPONSE AND DETECTION OF NEUTRALIZING ANTIBODIES." In Resumos do 54º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2022. http://dx.doi.org/10.5327/1516-3180.140s1.7075.

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Objective: Here we present the initial development and characterization of the Sars-CoV-2 NT-Chip. This test allows combining general detection of binding antibodies against RBDs (humoral signature) and, in the same assay, to detect and quantify the subset of these antibodies that promote functional neutralization against Sars-CoV-2 infection. Moreover, high detection of antibodies against N suggests previous infection for Omicron-positive samples. Method: The Sars-CoV-2 VOC Virachip IgG test was first developed to promote a multiplex detection of binding antibodies against the Sars-CoV-2 prot
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