Academic literature on the topic 'Modified Morpholino Nucleosides'

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Journal articles on the topic "Modified Morpholino Nucleosides"

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Zhang, Nan, Chunyan Tan, Puqin Cai, Peizhuo Zhang, Yufen Zhao, and Yuyang Jiang. "RNA interference in mammalian cells by siRNAs modified with morpholino nucleoside analogues." Bioorganic & Medicinal Chemistry 17, no. 6 (2009): 2441–46. http://dx.doi.org/10.1016/j.bmc.2009.02.001.

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Nandi, Bappaditya, Sankha Pattanayak, Sibasish Paul, and Surajit Sinha. "Synthesis of Nucleobase-Functionalized Morpholino-Modified Nucleoside Monomers Through Palladium-Catalyzed Cross-Coupling Reactions." European Journal of Organic Chemistry 2013, no. 7 (2013): 1271–86. http://dx.doi.org/10.1002/ejoc.201201384.

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Nandi, Bappaditya, Sankha Pattanayak, Sibasish Paul, and Surajit Sinha. "ChemInform Abstract: Synthesis of Nucleobase-Functionalized Morpholino-Modified Nucleoside Monomers Through Palladium-Catalyzed Cross-Coupling Reactions." ChemInform 44, no. 35 (2013): no. http://dx.doi.org/10.1002/chin.201335159.

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Papis, Marta, Camilla Loro, Michele Penso, Gianluigi Broggini, and Francesca Foschi. "Synthesis of Morpholino Nucleosides Starting From Enantiopure Glycidol." Organic Chemistry Frontiers, 2022. http://dx.doi.org/10.1039/d2qo00400c.

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A protocol for the synthesis of modified morpholino monomers was performed in few steps through the condensation between 6-hydroxymethyl-morpholine acetal and nucleobases under Lewis acid conditions. The key common precursor...
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Bege, Miklós, Vigyasa Singh, Neha Sharma, et al. "In vitro and in vivo antiplasmodial evaluation of sugar-modified nucleoside analogues." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-39541-4.

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AbstractDrug-resistant Plasmodium falciparum (Pf) infections are a major burden on the population and the healthcare system. The establishment of Pf resistance to most existing antimalarial therapies has complicated the problem, and the emergence of resistance to artemisinin derivatives is even more concerning. It is increasingly difficult to cure malaria patients due to the limited availability of effective antimalarial drugs, resulting in an urgent need for more efficacious and affordable treatments to eradicate this disease. Herein, new nucleoside analogues including morpholino-nucleoside h
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Dissertations / Theses on the topic "Modified Morpholino Nucleosides"

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Pattanayak, Sankha. "Design, Synthesis and Biological Applications of Modified Morpholino Nucleosides." Thesis, 2019. http://hdl.handle.net/10821/8240.

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The work embodied in this thesis entitled “Design, Synthesis and Biological Applications of Modified Morpholino Nucleosides” was initiated by the author in February, 2008 in the Department of Organic Chemistry, Indian Association for the Cultivation of Science, Kolkata under the supervision of Dr. Surajit Sinha. In Chapter 1, a general introduction of the antisense oligonucleotide field has been presented. The important members and major challenges of antisense oligos have been briefly discussed. In Chapter 2‐Part A, development of a considerably improved protocol for the synthesis of flexibly
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