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Journal articles on the topic 'Modified rankin scale'

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Published: 4 June 2021

Last updated: 26 July 2025

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1

Bruno, Askiel, Abiodun E. Akinwuntan, Chen Lin, et al. "Simplified Modified Rankin Scale Questionnaire." Stroke 42, no. 8 (2011): 2276–79. http://dx.doi.org/10.1161/strokeaha.111.613273.

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Quinn, Terence J., Jesse Dawson, Matthew R. Walters, and Kennedy R. Lees. "Reliability of the Modified Rankin Scale." Stroke 40, no. 10 (2009): 3393–95. http://dx.doi.org/10.1161/strokeaha.109.557256.

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3

Burn, J. P. "Reliability of the modified Rankin Scale." Stroke 23, no. 3 (1992): 438. http://dx.doi.org/10.1161/str.23.3.438b.

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ElHabr, Andrew K., Jeffrey M. Katz, Jason Wang, et al. "Predicting 90-day modified Rankin Scale score with discharge information in acute ischaemic stroke patients following treatment." BMJ Neurology Open 3, no. 1 (2021): e000177. http://dx.doi.org/10.1136/bmjno-2021-000177.

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ObjectivesTo understand variability in modified Rankin Scale scores from discharge to 90 days in acute ischaemic stroke patients following treatment, and examine prediction of 90-day modified Rankin Scale score by using discharge modified Rankin Scale and discharge disposition.Materials and methodsRetrospective analysis of acute ischaemic stroke patients following treatment was performed from January 2016 to March 2020. Data collection included demographic and clinical characteristics and outcomes data (modified Rankin Scale score at discharge, 30 days and 90 days and discharge disposition). P

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Dewilde, Sarah, Lieven Annemans, Andre Peeters, et al. "Modified Rankin scale as a determinant of direct medical costs after stroke." International Journal of Stroke 12, no. 4 (2017): 392–400. http://dx.doi.org/10.1177/1747493017691984.

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Background Resource use in the acute and subacute phases after stroke depends on the degree of disability. Aims To determine if direct costs after stroke also vary by level of disability as measured using the modified Rankin scale at the chronic stage after stroke. Methods In a multicentre study, we collected acute and chronic in- and outpatient resource use in survivors of ischemic stroke stratified by levels of disability according to the modified Rankin Scale. Statistical inference on costs at each level of the modified Rankin Scale was estimated using a general linear model for the first t

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Gao, Yan, Yulong Wang, Dongxia Li, et al. "Disability assessment in stroke: Relationship among the pictorial-based Longshi Scale, the Barthel Index, and the modified Rankin Scale." Clinical Rehabilitation 35, no. 4 (2021): 606–13. http://dx.doi.org/10.1177/0269215520975922.

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Objective: To explore the correlations among the Longshi Scale, the Barthel Index, and the modified Rankin Scale and the differentiate ability of the Longshi Scale and the modified Rankin Scale to Barthel Index scores. Design: Prospective study. Setting: The inpatient rehabilitation units of three teaching hospitals in China. Subjects: A total of 343 stroke inpatients were recruited through convenience sampling. Main measures: Pictorial-based Longshi Scale, Barthel Index, and modified Rankin Scale. Results: The Longshi Scale was highly and moderately correlated with the Barthel Index and modif

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Bruno, Askiel, Jeffrey A. Switzer, Valerie L. Durkalski, and Fenwick T. Nichols. "Is a Prestroke Modified Rankin Scale Sensible?" International Journal of Stroke 6, no. 5 (2011): 414–15. http://dx.doi.org/10.1111/j.1747-4949.2011.00661.x.

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Yi, Kenichiro, Shuhei Okazaki, Manabu Inoue, et al. "Reliability of modified Rankin Scale assessment with a Japanese version of simplified modified Rankin Scale Questionnaire (J-RASQ)." Rinsho Shinkeigaku 59, no. 7 (2019): 399–404. http://dx.doi.org/10.5692/clinicalneurol.cn-001295.

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Wang, Mengxi, Suja S. Rajan, Asha P. Jacob, et al. "Retrospective collection of 90-day modified Rankin Scale is accurate." Clinical Trials 17, no. 6 (2020): 637–43. http://dx.doi.org/10.1177/1740774520942466.

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Background: The 90-day modified Rankin Scale is a widely used outcome after stroke but is sometimes hard to ascertain due to loss to follow-up. Missing outcomes can result in biased and/or inefficient estimates in clinical trials. The aim of this study is to assess the validity of acquiring the 90-day modified Rankin Scale at a later point of time when the patient has been lost at 90 days to impute the missing value. Methods: Participants who had prospectively completed a 90-day modified Rankin Scale questionnaire on their own in the Benefits of Stroke Treatment Using a Mobile Stroke Unit stud

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Quinn, Terence J., Jesse Dawson, Matthew R. Walters, and Kennedy R. Lees. "Exploring the Reliability of the Modified Rankin Scale." Stroke 40, no. 3 (2009): 762–66. http://dx.doi.org/10.1161/strokeaha.108.522516.

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11

Chakrabartty, Satyendra Nath. "Alternate Measure of Disability Intensity: Modified Rankin Scale." Journal of Stroke Medicine 2, no. 2 (2019): 111–18. http://dx.doi.org/10.1177/2516608519870703.

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Objective: This study was aimed to propose an alternate method of scoring the intensity of disability in a patient, which will facilitate ranking and classifying a group of patients in mutually exclusive classes along with the quantification of progress made by a patient or the effect of interventions and also tracking the path of improvement of a patient and estimating the survival curve for drawing useful conclusions. Method: A nonparametric measure of disability intensity in terms of Cos θi for the ith patient is proposed to avoid limitations of the usual scoring of modified Rankin scale an

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Suponeva, N. A., D. G. Yusupova, E. S. Zhirova, et al. "Validation of the modified Rankin Scale in Russia." Neurology, Neuropsychiatry, Psychosomatics 10, no. 4 (2018): 36–39. http://dx.doi.org/10.14412/2074-2711-2018-4-36-39.

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Objective: to develop a Russian version of the modified Rankin Scale (mRS) and to assess its psychometric properties.Patients and methods. The investigation involved 50 patients (25 women, 25 men) over 18 years of age (mean age, 56 years) with an acute cerebrovascular accident diagnosis. During the validation procedure, the authors carried out the linguocultural ratification of mRS, prepared its Russian-language version, and then assessed its psychometric properties (reliability, sensitivity, validity).Results and discussion. Translation and linguistic adaptation of mRS was successfully comple

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Isaksson, Eva, Per Wester, Ann Charlotte Laska, Per Näsman, and Erik Lundström. "Validation of the Simplified Modified Rankin Scale Questionnaire." European Neurology 83, no. 5 (2020): 493–99. http://dx.doi.org/10.1159/000510721.

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<b><i>Introduction:</i></b> The modified Rankin scale (mRS) is the most common assessment tool for measuring overall functional outcome in stroke studies. The traditional way of using mRS face-to-face is time- and cost-consuming. The aim of this study was to test the validity of the Swedish translation of the simplified modified Rankin scale questionnaire (smRSq) as compared with the mRS assessed face-to-face 6 months after a stroke. <b><i>Methods:</i></b> Within the ongoing EFFECTS trial, smRSq was sent out to 108 consecutive stroke patients 6 m

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McArthur, Kate, Michael L. C. Beagan, Andrew Degnan, et al. "Properties of Proxy-Derived Modified Rankin Scale Assessment." International Journal of Stroke 8, no. 6 (2012): 403–7. http://dx.doi.org/10.1111/j.1747-4949.2011.00759.x.

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Rebchuk, Alexander D., Zoe R. O’Neill, Elena K. Szefer, Michael D. Hill, and Thalia S. Field. "Health Utility Weighting of the Modified Rankin Scale." JAMA Network Open 3, no. 4 (2020): e203767. http://dx.doi.org/10.1001/jamanetworkopen.2020.3767.

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Wu, Di, Longfei Wu, Jian Chen, et al. "Primate Version of Modified Rankin Scale for Classifying Dysfunction in Rhesus Monkeys." Stroke 51, no. 5 (2020): 1620–23. http://dx.doi.org/10.1161/strokeaha.119.028108.

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Background and Purpose— Nonhuman primates are increasingly used in translational studies of ischemic stroke. However, current scoring systems in monkeys (eg, Nonhuman Primate Stroke Scale) do not focus on impairments in activities of daily living, so clinically relevant data are scarce for evaluating functional deficits in this model. Methods— Here, we referenced the modified Rankin Scale to provide a primate version of Rankin Scale (pRS) for ranking neurological dysfunction in monkeys following stroke. We selected hand function and strength, level of activity, and general mobility as the main

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Goyal, Mayank, Aravind Ganesh, Scott Brown, Bijoy K. Menon, and Michael D. Hill. "Suggested modification of presentation of stroke trial results." International Journal of Stroke 13, no. 7 (2018): 669–72. http://dx.doi.org/10.1177/1747493018778122.

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The modified Rankin Scale (mRS) at 90 days after stroke onset has become the preferred outcome measure in acute stroke trials, including recent trials of interventional therapies. Reporting the range of modified Rankin Scale scores as a paired horizontal stacked bar graph (colloquially known as “Grotta bars”) has become the conventional method of visualizing modified Rankin Scale results. Grotta bars readily illustrate the levels of the ordinal modified Rankin Scale in which benefit may have occurred. However, complementing the available graphical information by including additional features t

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Wilson, Alastair, Philip MW Bath, Eivind Berge, et al. "Understanding the relationship between costs and the modified Rankin Scale: A systematic review, multidisciplinary consensus and recommendations for future studies." European Stroke Journal 2, no. 1 (2016): 3–12. http://dx.doi.org/10.1177/2396987316684705.

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Background and purpose Cost-of-illness studies often describe a single aggregate cost of a disease state. This approach is less helpful for a condition with a spectrum of outcomes like stroke. The modified Rankin Scale is the most commonly used outcome measure for stroke. We sought to describe the existing evidence on the costs of stroke according to individual modified Rankin Scale categories. This may be useful in future cost effectiveness modelling studies of interventions where cost data have not been collected, but disability outcome is known. Methods Systematic review of the published li

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Savio, Katia, Gian Luca Della Pietra, Elodie Oddone, Monica Reggiani, and Maurizio A. Leone. "Reliability of the modified Rankin Scale applied by telephone." Neurology International 5, no. 1 (2013): 2. http://dx.doi.org/10.4081/ni.2013.e2.

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We aimed to evaluate the reliability of the modified Rankin Scale applied telephonically compared with face-to-face assessment in clinically stable hospitalized patients with acute stroke. One hundred and thirty-one patients were interviewed twice by 2 certified nurses (unstructured interview). Half of the patients were randomized to be interviewed by telephone followed by the face-to-face assessment, and half in the reverse order. The median value of the modified Rankin Scale score was 4 (first to third interquartile range 3-5) by telephone as well as by face-to-face assessment (P=0.8). The w

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Zerna, Charlotte, Tyler Burley, Theresa L. Green, Sean P. Dukelow, Andrew M. Demchuk, and Michael D. Hill. "Comprehensive assessment of disability post-stroke using the newly developed miFUNCTION scale." International Journal of Stroke 15, no. 2 (2019): 167–74. http://dx.doi.org/10.1177/1747493019840933.

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Background and Purpose The modified Rankin Scale (mRS) is the most widely used primary outcome measure in acute stroke trials. However, substantial interobserver variability impairs outcome assessment as well as reduces power of clinical trials. Guided by the International Classification of Functioning, Disability and Health, we developed a comprehensive, hierarchical assessment tool (miFUNCTION) to address the shortcomings of the modified Rankin Scale and deliver a more thorough understanding of disability following stroke. Methods The initial construct validity of miFUNCTION was established

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Wilson, J. T. Lindsay, Asha Hareendran, Anne Hendry, Jan Potter, Ian Bone, and Keith W. Muir. "Reliability of the Modified Rankin Scale Across Multiple Raters." Stroke 36, no. 4 (2005): 777–81. http://dx.doi.org/10.1161/01.str.0000157596.13234.95.

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Bruno, Askiel, Neel Shah, Chen Lin, et al. "Improving Modified Rankin Scale Assessment With a Simplified Questionnaire." Stroke 41, no. 5 (2010): 1048–50. http://dx.doi.org/10.1161/strokeaha.109.571562.

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Bruno, Askiel, Brian Close, Jeffrey A. Switzer, et al. "Simplified modified Rankin Scale questionnaire correlates with stroke severity." Clinical Rehabilitation 27, no. 8 (2013): 724–27. http://dx.doi.org/10.1177/0269215512470674.

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Schulz, Ursula, Tracey Baird, Marie Grant, et al. "Validity of a structured interview for the Modified Rankin Scale: Comparison with other stroke assessment scales." Stroke 32, suppl_1 (2001): 333. http://dx.doi.org/10.1161/str.32.suppl_1.333-d.

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98 Background & aims: We have recently developed a structured interview for the Modified Rankin Scale (MRS-SI) to improve the inter-rater reliability of this measure of outcome. The purpose of the current study was to investigate the relationship between the MRS-SI and other measures commonly used to assess functional state after stroke. Methods: 119 patients (60 males) were recruited to the study 3 to 24 months after stroke. The median age of patients was 67, and the median interval since stroke was 13 months. Patients were assessed on the Modified Rankin Scale using the structured interv

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Ashraf, Ali Shuaib, Ali Hassan, Muhammad Hamza Saeed, Arsalan Shamim, Haleem Hammad, and Yasir Salim. "Prevalence of Hypocalcemia in Patients with Acute Ischemic Stroke at a Tertiary Care Hospital." Pakistan Journal of Medical and Health Sciences 17, no. 4 (2023): 683–85. http://dx.doi.org/10.53350/pjmhs2023174683.

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Objective: To ascertain the prevalence of hypocalcemia in patients with acute ischemic stroke at a tertiary care hospital and to analyze the mean scores on the modified Rankin Scale, assessing the stroke severity, in patients both with and without hypocalcemia." Study Design: It was a cross sectional study. Setting: Deptt. of Medicine, Services Hospital, Lahore. Methodology: 100 eligible patients were examined the modified Rankin scale at the time of presentation, recording the scores. To ensure accuracy, overnight fasting was observed, and a 5 ml early morning fasting blood sample was collect

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Etedal, Ahmed AbuElbasher Ibrahim. "The Outcome of Acute Ischemic Stroke in Sudanese patients on Dual Anti-platelet Therapy Clopidogrel and Aspirin vs. Aspirin using modified Ranking scale at the National Centre for Neurological Science." Journal of Neurology, Neurosurgery & Psychiatry Research 1, no. 1 (2019): 1–8. https://doi.org/10.31531/edwiser.jnnpr.1000105.

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Background: Stroke or cerebrovascular accident (CVA) is defined as the sudden occurrence of a focal, non-conclusive neurological deficit; with variable consequences, ranging from subtle to very severe disabilities, depending on the area of the brain involved and the nature of the attack. Anti-platelet therapy such as aspirin and clopidogrel is used for both management and prevention of stroke, it reduced the incidence of stroke in patients at high risk for atherosclerosis and in those with known symptomatic cerebrovascular disease. Objective: To assess the difference in the outcome of dual ant

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Sarder, AH, BK Das, KJ Mondal, MA Kabir, B. Basu, and MM Alam. "30-days’ outcome of haemorrhagic stroke: correlation between intracerebral hemorrhage score and modified Rankin score." Mediscope 5, no. 1 (2018): 10–14. http://dx.doi.org/10.3329/mediscope.v5i1.36720.

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Intracerebral hemorrhage (ICH) constitutes 10% to 15% of all strokes. Within 30 days reported mortality is 35-52% and only 20% is functionally independent in 6 months. Despite several existing outcome prediction models for ICH, modified Rankin scale is found to be best predictor of outcome in early and long term period. To find out 30-day mortality in ICH and predict outcome based on modified Rankin score. In this study, 48 patients presenting with acute ICH presenting to a tertiary hospital in Khulna were enrolled. The 30-day mortality and disability were recorded, and ICH score along with mo

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Cramer, Steven C., Vu Le, Jeffrey L. Saver, et al. "Intense Arm Rehabilitation Therapy Improves the Modified Rankin Scale Score." Neurology 96, no. 14 (2021): e1812-e1822. http://dx.doi.org/10.1212/wnl.0000000000011667.

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ObjectiveTo evaluate the effect of intensive rehabilitation on the modified Rankin Scale (mRS), a measure of activities limitation commonly used in acute stroke studies, and to define the specific changes in body structure/function (motor impairment) most related to mRS gains.MethodsPatients were enrolled >90 days poststroke. Each was evaluated before and 30 days after a 6-week course of daily rehabilitation targeting the arm. Activity gains, measured using the mRS, were examined and compared to body structure/function gains, measured using the Fugl-Meyer (FM) motor scale. Additional analys

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Yi, Kenichiro, Makoto Nakajima, Tomoaki Ikeda, Mineko Yoshigai, and Mitsuharu Ueda. "Modified Rankin scale assessment by telephone using a simple questionnaire." Journal of Stroke and Cerebrovascular Diseases 31, no. 10 (2022): 106695. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2022.106695.

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Bârsan, Ioana Cristina, Silvina Iluţ, Nicoleta Tohănean, et al. "Predicting 6-month modified Rankin Scale score in stroke patients." Balneo and PRM Research Journal 15, Vol.15, no. 3 (2024): 731. http://dx.doi.org/10.12680/balneo.2024.731.

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The study aimed to identify predictors of 6-month outcomes in acute ischemic stroke (AIS) patients using the modified Rankin Scale (mRS). A prospective observational cohort study was conducted on 277 AIS patients admitted to the Neurology Departments of Cluj-Napoca Emergency County Clinical Hospital between December 2020 and July 2021. After excluding those lost to follow-up or who withdrew due to COVID-19 concerns, 121 patients were followed for six months. Data collected included demographic details, clinical assessments (including NIHSS and mRS scores), laboratory tests, and imaging results

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Weiss, Daniel, Bastian Kraus, Christian Rubbert, et al. "Systematic evaluation of computed tomography angiography collateral scores for estimation of long-term outcome after mechanical thrombectomy in acute ischaemic stroke." Neuroradiology Journal 32, no. 4 (2019): 277–86. http://dx.doi.org/10.1177/1971400919847182.

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Purpose This study compares computed tomography angiography-based collateral scoring systems in regard to their inter-rater reliability and potential to predict functional outcome after endovascular thrombectomy, and relates them to parenchymal perfusion as measured by computed tomography perfusion. Methods Eighty-four patients undergoing endovascular thrombectomy in anterior circulation ischaemic stroke were enrolled. Modified Tan Score, Miteff Score, Maas Score and Opercular Index Score ratio were assessed in pre-interventional computed tomography angiographies independently by two readers.

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Abdalkader, Mohamad, Shen Ning, Muhammad M. Qureshi, et al. "Sex Differences in Outcomes of Late-Window Endovascular Stroke Therapy." Stroke 55, no. 2 (2024): 278–87. http://dx.doi.org/10.1161/strokeaha.123.045015.

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BACKGROUND: The association between sex and outcome after endovascular thrombectomy of acute ischemic stroke is unclear. The aim of this study was to compare the clinical and safety outcomes between men and women treated with endovascular thrombectomy in the late 6-to-24-hour window period. METHODS: This multicenter, retrospective observational cohort study included consecutive patients who underwent endovascular thrombectomy of anterior circulation stroke in the late window from 66 clinical sites in 10 countries from January 2014 to May 2022. The primary outcome was the 90-day ordinal modifie

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Baker, Alexandra Delaney, Krissia Margarita Rivera Perla, Zhiyuan Yu, et al. "Fibrinolytic for treatment of intraventricular hemorrhage: A meta-analysis and systematic review." International Journal of Stroke 13, no. 1 (2017): 11–23. http://dx.doi.org/10.1177/1747493017730745.

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Background Intraventricular hemorrhage is a significant cause of mortality and morbidity worldwide. Treating intraventricular hemorrhage with intraventricular fibrinolytic therapy via a catheter is becoming an increasingly utilized intervention. Aims This meta-analysis aimed to investigate the role of intraventricular fibrinolytic treatment in hypertensive intraventricular hemorrhage patients and evaluate the effect sizes for survival as well as level of function at differing time points. Summary of review PubMed, CNKI, VIP, and Wanfang were searched using the terms “IVH” and “IVH and ICH” for

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Eskioglou, Elissavet, Mitra Huchmandzadeh Millotte, Michael Amiguet, and Patrik Michel. "National Institutes of Health Stroke Scale Zero Strokes." Stroke 49, no. 12 (2018): 3057–59. http://dx.doi.org/10.1161/strokeaha.118.022517.

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Background and Purpose— We aimed to characterize acute ischemic stroke patients who have an immeasurable deficit on the admission National Institutes of Health Stroke Scale (NIHSS), and to evaluate their long-term outcome. Methods— We retrospectively compared all acute ischemic stroke patients with an admission NIHSS of 0 in the Acute Stroke Registry and Analysis of Lausanne from 2003 to 2013 with all other acute ischemic stroke patients. We compared demographics, clinical, radiological, and laboratory findings. Outcome was considered favorable at 3 months if the modified Rankin Scale score co

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Kawabata, Yasuhiro, Norio Nakajima, Hidenori Miyake, Shunichi Fukuda, and Tetsuya Tsukahara. "Endovascular treatment of acute ischaemic stroke in octogenarians and nonagenarians compared with younger patients." Neuroradiology Journal 32, no. 4 (2019): 303–8. http://dx.doi.org/10.1177/1971400919840847.

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Purpose: Endovascular therapy for emergent large vessel occlusion has been established as the standard approach for acute ischaemic stroke. However, the effectiveness and safety of endovascular therapy in the very elderly population has not been proved. Objective: To determine the safety and effectiveness of endovascular therapy in octogenarians and nonagenarians. Methods: We retrospectively reviewed all patients who underwent endovascular therapy at two stroke centres between April 2012 and July 2018. Functional outcome was assessed using the modified Rankin scale at 90 days after stroke or a

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Lahiri, Shouri, Hooman Kamel, Emma E. Meyers, et al. "Patient-Powered Reporting of Modified Rankin Scale Outcomes Via the Internet." Neurohospitalist 6, no. 1 (2015): 11–13. http://dx.doi.org/10.1177/1941874415593760.

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Bruno, A., S. Sethuraman, MJ Sedler, et al. "First application of a Spanish version simplified modified Rankin Scale questionnaire." International Journal of Stroke 14, no. 5 (2019): NP12. http://dx.doi.org/10.1177/1747493019832983.

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Dijkland, Simone A., Daphne C. Voormolen, Esmee Venema, et al. "Utility-Weighted Modified Rankin Scale as Primary Outcome in Stroke Trials." Stroke 49, no. 4 (2018): 965–71. http://dx.doi.org/10.1161/strokeaha.117.020194.

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Rinkel, Leon A., T. Truc My Nguyen, Valeria Guglielmi, et al. "High Admission Glucose Is Associated With Poor Outcome After Endovascular Treatment for Ischemic Stroke." Stroke 51, no. 11 (2020): 3215–23. http://dx.doi.org/10.1161/strokeaha.120.029944.

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Background and Purpose: High-serum glucose on admission is a predictor of poor outcome after stroke. We assessed the association between glucose concentrations and clinical outcomes in patients who underwent endovascular treatment. Methods: From the MR CLEAN Registry, we selected consecutive adult patients with a large vessel occlusion of the anterior circulation who underwent endovascular treatment and for whom admission glucose levels were available. We assessed the association between admission glucose and the modified Rankin Scale score at 90 days, symptomatic intracranial hemorrhage and s

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Ahmed, Niaz, Kennedy R. Lees, Rudiger von Kummer, et al. "The SITS Open Study." Stroke 52, no. 3 (2021): 792–801. http://dx.doi.org/10.1161/strokeaha.120.031031.

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Background and Purpose: We designed SITS (Safe Implementation of Treatment in Stroke) Open to determine benefit and safety of thrombectomy in clinical practice for large artery occlusion stroke, using selected stent retrievers plus standard care versus standard care alone. Methods: SITS Open was a prospective, open, blinded evaluation, international, multicenter, controlled, nonrandomized registry study. Centers lacking access to thrombectomy contributed controls. Primary end point was categorical shift in modified Rankin Scale score at 3 months in the per protocol (PP) population. Principal s

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Youn, Hye-soo, Sun-woo Kwon, Choong-hyun Park, et al. "A Case Report of a Patient with Multiple Cerebral Infarction Caused by Posterior Cerebral Artery Occlusion Treated with <i>Yikgeebohyul-tang</i>." Journal of Internal Korean Medicine 43, no. 5 (2022): 951–59. http://dx.doi.org/10.22246/jikm.2022.43.5.951.

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Objectives: The aim of this study is to describe the effects of treatment with traditional Korean medicine on a patient with multiple cerebral infarction caused by posterior cerebral artery occlusion.Methods: The patient was treated with herbal medicine (<i>Yikgeebohyul-tang</i>) and acupuncture. The effects of these treatments were evaluated using the Manual Muscle Test, the Korean version of the Modified Barthel Index, the Modified Rankin scale, and a subjective percentage of sensation in the left lower extremity and face.Results: After treatment, the Modified Rankin Scale score,

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Novotny, Vojtech, Andrej N. Khanevski, Anna T. Bjerkreim, et al. "Short-Term Outcome and In-Hospital Complications After Acute Cerebral Infarcts in Multiple Arterial Territories." Stroke 50, no. 12 (2019): 3625–27. http://dx.doi.org/10.1161/strokeaha.119.027049.

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Background and Purpose— Patients with acute cerebral infarcts in multiple arterial territories (MACI) represent a substantial portion of the stroke population. There are no data on short-term outcome and in-hospital complications in patients with MACI. We compared patients with MACI with patients having acute cerebral infarct(s) in a single arterial territory. Methods— We analyzed 3343 patients with diffusion-weighted imaging-confirmed acute cerebral infarcts. MACI was defined as at least 2 acute cerebral ischemic lesions in at least 2 arterial cerebral territories. Patients with MACI were com

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Mohamed, Ghada A., Hassan Aboul Nour, Raul G. Nogueira, et al. "Repeated Mechanical Endovascular Thrombectomy for Recurrent Large Vessel Occlusion: A Multicenter Experience." Stroke 52, no. 6 (2021): 1967–73. http://dx.doi.org/10.1161/strokeaha.120.033393.

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Background and Purpose: Mechanical thrombectomy (MT) is now the standard of care for large vessel occlusion (LVO) stroke. However, little is known about the frequency and outcomes of repeat MT (rMT) for patients with recurrent LVO. Methods: This is a retrospective multicenter cohort of patients who underwent rMT at 6 tertiary institutions in the United States between March 2016 and March 2020. Procedural, imaging, and outcome data were evaluated. Outcome at discharge was evaluated using the modified Rankin Scale. Results: Of 3059 patients treated with MT during the study period, 56 (1.8%) unde

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van Doormaal, Tristan P. C., Albert van der Zwan, Bon H. Verweij, Kuo S. Han, David J. Langer, and Cornelis A. F. Tulleken. "TREATMENT OF GIANT MIDDLE CEREBRAL ARTERY ANEURYSMS WITH A FLOW REPLACEMENT BYPASS USING THE EXCIMER LASER-ASSISTED NONOCCLUSIVE ANASTOMOSIS TECHNIQUE." Neurosurgery 63, no. 1 (2008): 12–22. http://dx.doi.org/10.1227/01.neu.0000335066.45566.d1.

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ABSTRACT OBJECTIVE To define the clinical value of the flow replacement bypass using the excimer laser-assisted nonocclusive anastomosis (ELANA) technique in the treatment of patients with a noncoilable, nonclippable giant intracranial aneurysm of the middle cerebral artery (MCA). METHODS Between 1999 and 2006, 22 patients with a giant intracranial aneurysm of the MCA were treated in our hospital with an ELANA flow replacement bypass and MCA occlusion. We collected data on patient characteristics, operative aspects, complications, and functional health scores using the modified Rankin Scale. M

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Rist, Pamela M., I.-Min Lee, Carlos S. Kase, J. Michael Gaziano, and Tobias Kurth. "Physical Activity and Functional Outcomes From Cerebral Vascular Events in Men." Stroke 42, no. 12 (2011): 3352–56. http://dx.doi.org/10.1161/strokeaha.111.619544.

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Background and Purpose— In studies enrolling patients with stroke, higher levels of prestroke physical activity are associated with better functional outcomes. However, prospective studies evaluating this association are sparse. Using a cohort of initially healthy men, we aimed to prospectively assess the association between physical activity and functional outcomes from cerebral vascular events. Methods— We conducted a prospective cohort study among 21 794 men enrolled in the Physician's Health Study who provided information on physical activity at baseline and who did not have a history of s

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Katsanos, Aristeidis H., Apostolos Safouris, Amrou Sarraj, et al. "Intravenous Thrombolysis With Tenecteplase in Patients With Large Vessel Occlusions." Stroke 52, no. 1 (2021): 308–12. http://dx.doi.org/10.1161/strokeaha.120.030220.

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Background and Purpose: Accumulating evidence from randomized controlled clinical trials suggests that tenecteplase may represent an effective treatment alternative to alteplase for acute ischemic stroke. In the present systematic review and meta-analysis, we sought to compare the efficacy and safety outcomes of intravenous tenecteplase to intravenous alteplase administration for acute ischemic stroke patients with large vessel occlusions (LVOs). Methods: We searched MEDLINE (Medical Literature Analysis and Retrieval System Online) and Scopus for published randomized controlled clinical trials

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Schwarz, Ghil, Angelo Cascio Rizzo, Marius Matusevicius, et al. "Reperfusion Treatments in Disabling Versus Nondisabling Mild Stroke due to Anterior Circulation Vessel Occlusion." Stroke 54, no. 3 (2023): 743–50. http://dx.doi.org/10.1161/strokeaha.122.041772.

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Background: The benefit of distinguishing between disabling versus nondisabling deficit in mild acute ischemic stroke due to endovascular thrombectomy-targetable vessel occlusion (EVT-tVO; including anterior circulation large and medium-vessel occlusion) is unknown. We compared safety and efficacy of acute reperfusion treatments in disabling versus nondisabling mild EVT-tVO. Methods: From the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register, we included consecutive acute ischemic stroke patients (2015–2021) treated within 4.5 hours, with full NIHSS items a

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Zhou, Yu, Pengfei Xing, Zifu Li, et al. "Effect of Occlusion Site on the Safety and Efficacy of Intravenous Alteplase Before Endovascular Thrombectomy: A Prespecified Subgroup Analysis of DIRECT-MT." Stroke 53, no. 1 (2022): 7–16. http://dx.doi.org/10.1161/strokeaha.121.035267.

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Background and Purpose: Recent trials showed thrombectomy alone was comparable to bridging therapy in patients with anterior circulation large vessel occlusion eligible for both intravenous alteplase and endovascular thrombectomy. We performed this study to examine whether occlusion site modifies the effect of intravenous alteplase before thrombectomy. Methods: This is a prespecified subgroup analysis of a randomized trial evaluating risk and benefit of intravenous alteplase before thrombectomy (DIRECT-MT [Direct Intra-Arterial Thrombectomy in Order to Revascularize AIS Patients With Large Ves

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Joarder, Md Aliuzzaman, AKM Bazlul Karim, Shariful Islam Sujon, et al. "Decompressive Hemicraniectomy in Hypertensive Basal Ganglia Hemorrhages." Pulse 8, no. 1 (2016): 38–42. http://dx.doi.org/10.3329/pulse.v8i1.28100.

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Objectives: The aim of this study was to analyze efficacy and safety of decompressive hemicraniectomy (DHC) in hypertensive basal ganglia hemorrhage (HBGH). Neurosurgical management of HBGH is still a controversial issue. Surgical techniques are diverse, from the open large craniotomy, to the minimally invasive techniques like stereotactic aspiration of the HBGH, endoscopic evacuation and stereotactic catheter drainage after instillation of thrombolytic agents. Decompressive hemicraniectomy lowers intracranial pressure and improves outcome in patients with HBGH.Methods: 8 patients with HBGH wh

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Castro-Afonso, Luís Henrique de, Guilherme Seizem Nakiri, Lucas Moretti Monsignore, et al. "The direct first pass aspiration technique in the treatment of acute ischemic stroke resulting from large vessel occlusions." Arquivos de Neuro-Psiquiatria 75, no. 7 (2017): 412–18. http://dx.doi.org/10.1590/0004-282x20170059.

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ABSTRACT Mechanical thrombectomy using stent retrievers is the standard treatment for acute ischemic stroke that results from large vessel occlusions. The direct aspiration first pass technique (ADAPT) has been proposed as an efficient, fast, and cost-effective thrombectomy strategy. The aim of this study was to assess the safety and efficacy of ADAPT. Methods Recanalization was assessed using the modified thrombolysis in cerebral infarction (mTICI) score. Neurological outcomes were assessed using the National Institutes of Health Stroke Scale and modified Rankin Scale. Results Fifteen patient

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