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Journal articles on the topic 'Modular Injury'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Engen, T. "Lightweight modular orthosis." Prosthetics and Orthotics International 13, no. 3 (1989): 125–29. http://dx.doi.org/10.3109/03093648909079419.

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Background and highlights are presented concerning the development of a new orthotic system judged to be “the most outstanding innovation in prosthetics and/or orthotics practice” during the 1986-1989 period. The first Brian Blatchford Prize was awarded at the Sixth World Congress of ISPO held in Kobe, Japan, November 12-17, 1989. The new development selected as most deserving of this award consists of a system utilizing inexpensive, lightweight, modular components which can be quickly assembled with a few hand tools to provide custom-fitted knee-ankle-foot orthoses for persons with paraplegia

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Li, Hong Xian, Mohamed Al-Hussein, Zhen Lei, and Ziad Ajweh. "Risk identification and assessment of modular construction utilizing fuzzy analytic hierarchy process (AHP) and simulation." Canadian Journal of Civil Engineering 40, no. 12 (2013): 1184–95. http://dx.doi.org/10.1139/cjce-2013-0013.

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Modular construction brings improved safety and mitigates risks of hazard and injury. However, modular construction technology is also challenged with a degree of uncertainty resulting from such internal and external factors as engineering, occupational, cultural, socio-economic, and financial. Since modular construction is by nature distinct from conventional construction, existing risk management research for onsite construction cannot be directly applied to modular construction. This paper describes research on the risk management associated with modular construction, focusing on: (1) ident

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Wodziński, Piotr, Szymon F. Dragan, Artur Krawczyk(, Mirosław Kulej, and Szymon Ł. Dragan. "OSS Implant Fracture as a Complication of Resection Arthroplasty Performed Following High-energy Knee Injury. Case Study." Ortopedia Traumatologia Rehabilitacja 21, no. 2 (2019): 129–38. http://dx.doi.org/10.5604/01.3001.0013.1917.

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Treatment of high-energy distal femoral fractures is highly demanding. Advances in osteosynthesis techniques now allow for successful treatment, but extensive bone defects associated with the injury can preclude stable bone healing. Modular arthroplasty may be an effective alternative in such cases. Most commonly used during periarticular tumour resection procedures, modular arthroplasty enables functional recovery of the limb. It has been proven to be effective also in traumatic bone defects. The most important limitation of this method is a high level of technical difficulty and possible co

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Cumplido-Trasmonte, Carlos, Eva Barquín-Santos, María Dolores Gor-García-Fogeda, et al. "STELO: A New Modular Robotic Gait Device for Acquired Brain Injury—Exploring Its Usability." Sensors 24, no. 1 (2023): 198. http://dx.doi.org/10.3390/s24010198.

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In recent years, the prevalence of acquired brain injury (ABI) has been on the rise, leading to impaired gait functionality in affected individuals. Traditional gait exoskeletons are typically rigid and bilateral and lack adaptability. To address this, the STELO, a pioneering modular gait-assistive device, was developed. This device can be externally configured with joint modules to cater to the diverse impairments of each patient, aiming to enhance adaptability and efficiency. This study aims to assess the safety and usability of the initial functional modular prototype, STELO, in a sample of

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Sun, W. W., K. Chen, X. H. Xu, and M. T. Mi. "The Application Study of Multifunctional Injuries-Simulating Platform." Advanced Materials Research 605-607 (December 2012): 1880–85. http://dx.doi.org/10.4028/www.scientific.net/amr.605-607.1880.

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Conversing with the high quality life brought by high-tech, special occupational groups including the military personals were confronted with even more worse operational environment, such as extreme heat, cold, humidity, intense light ,typhoon or manmade meteorological disasters, and noise, low-illumination, electromagnetic radiation from the weapon. Working in such conditions, operation efficiency, visual-auditory function, brain function and the ability of mental adaptation would be injured. However, there has no professional research platform for simulating multiple injury factors. The mult

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Pérez-Nombela, S., F. Barroso, D. Torricelli, et al. "Modular control of gait after incomplete spinal cord injury: differences between sides." Spinal Cord 55, no. 1 (2016): 79–86. http://dx.doi.org/10.1038/sc.2016.99.

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Clemmer, D. I. "A modular system for occupational injury coding based on the Haddon matrix." Journal of Occupational Accidents 12, no. 1-3 (1990): 201. http://dx.doi.org/10.1016/0376-6349(90)90103-3.

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Stănescu, Marius, Adrian Bogdan Popescu, and Zubaci Radu. "Advantages of Modular Radial Head Prosthesis Use in Highly Comminuted Fractures." Key Engineering Materials 745 (July 2017): 145–56. http://dx.doi.org/10.4028/www.scientific.net/kem.745.145.

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This article aims to evaluate the results and outcomes of patients with highly comminuted radial head fractures, Mason III / IV type, treated surgically by arthroplasty with a cemented modular radial head prosthesis. A fracture of the radial head with a high degree of comminution left untreated can lead to complex functional impairment in which both elbow flexion and extension and also the pronation / supination of the forearm are limited, all of which will affect their daily activities. Management of radial head fractures should be based on both injury-specific factors and patient factors. In

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Fox, Emily J., Nicole J. Tester, Steven A. Kautz, et al. "Modular control of varied locomotor tasks in children with incomplete spinal cord injuries." Journal of Neurophysiology 110, no. 6 (2013): 1415–25. http://dx.doi.org/10.1152/jn.00676.2012.

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A module is a functional unit of the nervous system that specifies functionally relevant patterns of muscle activation. In adults, four to five modules account for muscle activation during walking. Neurological injury alters modular control and is associated with walking impairments. The effect of neurological injury on modular control in children is unknown and may differ from adults due to their immature and developing nervous systems. We examined modular control of locomotor tasks in children with incomplete spinal cord injuries (ISCIs) and control children. Five controls (8.6 ± 2.7 yr of a

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Fomin, A. I., and T. V. Grunskoy. "Improvement of the Working Conditions of Oil Miners during the Transition from the Thermoshaft Method of High-Viscosity Oil Production to the Modular Mine Method of the Yaregskoye Field Development." Occupational Safety in Industry, no. 12 (December 2020): 58–65. http://dx.doi.org/10.24000/0409-2961-2020-12-58-65.

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The need for high-viscosity oil production in the fields of the Russian Federation is substantiated. The technology of high-viscosity oil production by the thermoshaft method is considered, harmful and hazardous factors at the workplaces of the underground group workers are identified, first of all, the microclimate parameters (increased air temperature of the working area), which effect on the formation of occupational diseases and an increase in the risk of injury to the personnel. The main problems associated with the imperfection of the technology of the thermoshaft method for the extracti

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Cumplido-Trasmonte, Carlos, Eva Barquín-Santos, María Dolores Gor-García-Fogeda, et al. "Modularity Implications of an Overground Exoskeleton on Plantar Pressures, Strength, and Spasticity in Persons with Acquired Brain Injury." Sensors 24, no. 5 (2024): 1435. http://dx.doi.org/10.3390/s24051435.

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This study explored the effects of a modular overground exoskeleton on plantar pressure distribution in healthy individuals and individuals with Acquired Brain Injury (ABI). The research involved 21 participants, including ABI patients and healthy controls, who used a unique exoskeleton with adaptable modular configurations. The primary objective was to assess how these configurations, along with factors such as muscle strength and spasticity, influenced plantar pressure distribution. The results revealed significant differences in plantar pressures among participants, strongly influenced by t

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Carlos, Alberto Alves Dias-Filho, Araújo Bezerra Brasil Pinheiro Joseana, Coelho Ferreira Andressa, et al. "ANALYSIS OF CARDIAC AUTONOMIC MODULATION, BIOCHEMICAL MARKERS AND SLEEP QUALITY IN WHEELCHAIR USERS WITH SPINAL CORD INJURY AND STRENGTH TRAINING." Revistaft 27, no. 120 (2023): 73. https://doi.org/10.5281/zenodo.7689373.

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<strong>Background:</strong> Spinal cord injury (LM) above T6 is followed by a loss of supraspinal sympathetic control of the heart, disrupting autonomic balance and increasing cardiovascular risk.<strong> Objective</strong>: To evaluate cardiac autonomic modulation, biochemical markers, and sleep quality in wheelchair users with spinal cord injury and strength training. <strong>Methods:</strong> A 12-week cross-sectional study included 50 male participants aged between 20 and 52 years. With the evaluation of anthropometric measurements and body composition, Biochemical eva

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Keen, Edward F., Katrin Mende, Heather C. Yun, et al. "Evaluation of Potential Environmental Contamination Sources for the Presence of Multidrug-Resistant Bacteria Linked to Wound Infections in Combat Casualties." Infection Control & Hospital Epidemiology 33, no. 9 (2012): 905–11. http://dx.doi.org/10.1086/667382.

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Objective.To determine whether multidrug-resistant (MDR) gram-negative organisms are present in Afghanistan or Iraq soil samples, contaminate standard deployed hospital or modular operating rooms (ORs), or aerosolize during surgical procedures.Design.Active surveillance.Setting.US military hospitals in the United States, Afghanistan, and Iraq.Methods.Soil samples were collected from sites throughout Afghanistan and Iraq and analyzed for presence of MDR bacteria. Environmental sampling of selected newly established modular and deployed OR high-touch surfaces and equipment was performed to deter

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14

Alsindi, Z., and D. Datta. "Quadriceps muscle injury in trans-femoral amputees." Prosthetics and Orthotics International 22, no. 3 (1998): 248–50. http://dx.doi.org/10.3109/03093649809164490.

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Two male trans-femoral amputees using modular trans-femoral prostheses lost control and fell to the ground when their prosthetic knees gave way. The semi-automatic knee lock malfunctioned in the first case while the free knee stabilising mechanics gave way in the second case. This resulted in a high tensile force acting on the contralateral quadriceps muscle causing it to rupture. As there are a significant number of patients with both kinds of prostheses it is important to be aware of this possibility so that necessary actions can be taken to minimise its occurrence. Even with the currently a

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Schmit, Brian D., T. George Hornby, Vicki M. Tysseling-Mattiace, and Ela N. Benz. "Absence of Local Sign Withdrawal in Chronic Human Spinal Cord Injury." Journal of Neurophysiology 90, no. 5 (2003): 3232–41. http://dx.doi.org/10.1152/jn.00924.2002.

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Local sign withdrawal, a reflex to direct the limb away from noxious cutaneous stimuli, is thought to be indicative of a modular organization of the spinal cord. To assess the integrity of such an organization of the spinal cord in chronic human spinal cord injury (SCI), we tested the electromyogram (EMG) and joint torque responses to cutaneous stimuli applied to 6 locations of the leg in 10 SCI volunteers and 3 spinal-intact controls. The 6 locations included the medial arch of the foot, the second metatarsal, the dorsum, the region over the sural nerve at the lateral malleolus, and the anter

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Naser, Mohd Abdul. "Evaluation of treatment of fracture neck femur with uncemented HA coated modular bipolar prosthesis." MedPulse International Journal of Orthopedics 20, no. 3 (2021): 61–65. http://dx.doi.org/10.26611/10202034.

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Background: Background: Fracture of the femoral neck has been reported with increasing incidence in recent times due to prevalence of osteoporosis. Uncemented HA coated modular bipolar hemiarthroplasty systems provide a customised press fit solution which improve the patient outcome with respect to limb length discreptancy. We report our series of 15 cases of fracture neck of femur operated over years with modular cementless HA bipolar hemiarthroplasty. Methods: 15 patients (age=50 to 70 years) with displaced femoral neck fractures were operated between January 2019 to December 2019. Cementles

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Rouleau, Nicolas, Mattia Bonzanni, Joshua D. Erndt-Marino, et al. "A 3D Tissue Model of Traumatic Brain Injury with Excitotoxicity That Is Inhibited by Chronic Exposure to Gabapentinoids." Biomolecules 10, no. 8 (2020): 1196. http://dx.doi.org/10.3390/biom10081196.

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Injury progression associated with cerebral laceration is insidious. Following the initial trauma, brain tissues become hyperexcitable, begetting further damage that compounds the initial impact over time. Clinicians have adopted several strategies to mitigate the effects of secondary brain injury; however, higher throughput screening tools with modular flexibility are needed to expedite mechanistic studies and drug discovery that will contribute to the enhanced protection, repair, and even the regeneration of neural tissues. Here we present a novel bioengineered cortical brain model of trauma

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Zhang, Xinxin, Tingting Wang, Xiangqing Fan, et al. "Development of a Modular miRNA-Responsive Biosensor for Organ-Specific Evaluation of Liver Injury." Biosensors 14, no. 9 (2024): 450. http://dx.doi.org/10.3390/bios14090450.

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MicroRNAs (miRNAs) are increasingly being considered essential diagnostic biomarkers and therapeutic targets for multiple diseases. In recent years, researchers have emphasized the need to develop probes that can harness extracellular miRNAs as input signals for disease diagnostics. In this study, we introduce a novel miRNA-responsive biosensor (miR-RBS) designed to achieve highly sensitive and specific detection of miRNAs, with a particular focus on targeted organ-specific visualization. The miR-RBS employs a Y-structured triple-stranded DNA probe (Y-TSDP) that exhibits a fluorescence-quenche

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Ruiz Vargas, E., D. G. V. Mitchell, S. G. Greening, and L. M. Wahl. "Network analysis of human fMRI data suggests modular restructuring after simulated acquired brain injury." Medical & Biological Engineering & Computing 54, no. 1 (2015): 235–48. http://dx.doi.org/10.1007/s11517-015-1396-2.

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Prevedello, Daniel M., Amin B. Kassam, Ricardo Carrau, et al. "The expanded endoscopic endonasal approaches for the skull base." JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA 19, no. 2 (2018): 18–29. http://dx.doi.org/10.22290/jbnc.v19i2.663.

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Background: Endoscopic endonasal approach (EEA) for skull base surgery (SBS) is a significant modification of the current practice. Methods: We reviewed our experience at the University of Pittsburgh with EEAs for 800 patients from 1998 to July 2007. Results: Modular approaches to multiple pathologies of the skull base were designed totally based on intrinsic anatomy. Stages of training were established based on the level of technical difficulty and potential risk of vascular and neural injury. Five levels were defined in an incremental manner. Conclusions: Practice standardization with modula

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Mitoma, Hiroshi, Shinji Kakei, Kazuhiko Yamaguchi, and Mario Manto. "Physiology of Cerebellar Reserve: Redundancy and Plasticity of a Modular Machine." International Journal of Molecular Sciences 22, no. 9 (2021): 4777. http://dx.doi.org/10.3390/ijms22094777.

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The cerebellum is endowed with the capacity for compensation and restoration after pathological injury, a property known as cerebellar reserve. Such capacity is attributed to two unique morphological and physiological features of the cerebellum. First, mossy fibers that convey peripheral and central information run mediolaterally over a wide area of the cerebellum, resulting in the innervation of multiple microzones, commonly known as cerebellar functional units. Thus, a single microzone receives redundant information that can be used in pathological conditions. Secondly, the circuitry is char

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Schlotterose, Luise, Megane Beldjilali-Labro, Gaya Schneider, et al. "Traumatic Brain Injury in a Well: A Modular Three-Dimensional Printed Tool for Inducing Traumatic Brain Injury In vitro." Neurotrauma Reports 4, no. 1 (2023): 255–66. http://dx.doi.org/10.1089/neur.2022.0072.

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Negro-Demontel, María Luciana, Paolo Saccardo, Cecilia Giacomini, et al. "Comparative analysis of lentiviral vectors and modular protein nanovectors for traumatic brain injury gene therapy." Molecular Therapy - Methods & Clinical Development 1 (2014): 14047. http://dx.doi.org/10.1038/mtm.2014.47.

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Cockram, Michael S., and Ketan Jung Dulal. "Injury and mortality in broilers during handling and transport to slaughter." Canadian Journal of Animal Science 98, no. 3 (2018): 416–32. http://dx.doi.org/10.1139/cjas-2017-0076.

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Multiple factors affect the risk of broiler injury and mortality during loading, transport, and lairage. These include the physical and pathophysiological condition of broilers before loading and the type of handling procedures used. The external environmental conditions have a major influence on the risk of mortality. Combinations of high stocking density, insufficient ventilation, and high temperature and humidity pose a risk of hyperthermia. Combinations of wet conditions, cold temperature, and air movement, increase the risk of hypothermia. However, protection from cold and wet conditions

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Hey, Grace, Ilyas Mehkri, Yusuf Mehkri, et al. "Nanoparticle-Based Therapies for Management of Subarachnoid Hemorrhage, Neurotrauma, and Stroke." Biomedicines 13, no. 1 (2024): 16. https://doi.org/10.3390/biomedicines13010016.

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Neurotrauma, stroke, and subarachnoid hemorrhage (SAH) are symptomatically diverse and etiologically complex central nervous system pathologies. Despite numerous therapeutic modalities that are available to minimize neurologic damage and secondary injury, the prognosis can still be dismal and unpredictable. Nanoparticle (NP) technology allows for deliberate, modular, and minimally invasive drug delivery. This literature review encompasses pertinent information on the impact and versatility of nanoparticle therapeutics when treating neurotrauma, stroke, and SAH. Currently, notable treatments su

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Schyman, Patric, Richard L. Printz, Shanea K. Estes, Tracy P. O’Brien, Masakazu Shiota, and Anders Wallqvist. "Concordance between Thioacetamide-Induced Liver Injury in Rat and Human In Vitro Gene Expression Data." International Journal of Molecular Sciences 21, no. 11 (2020): 4017. http://dx.doi.org/10.3390/ijms21114017.

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The immense resources required and the ethical concerns for animal-based toxicological studies have driven the development of in vitro and in silico approaches. Recently, we validated our approach in which the expression of a set of genes is uniquely associated with an organ-injury phenotype (injury module), by using thioacetamide, a known liver toxicant. Here, we sought to explore whether RNA-seq data obtained from human cells (in vitro) treated with thioacetamide-S-oxide (a toxic intermediate metabolite) would correlate across species with the injury responses found in rat cells (in vitro) a

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Qi, Quan, Yibo Yan, Cheng Luo, et al. "Bioinformatics Analysis Reveals Hub Genes That May Reduce Inflammation and Complications After Cardiopulmonary Bypass." Heart Surgery Forum 25, no. 2 (2022): E243—E252. http://dx.doi.org/10.1532/hsf.4487.

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Cardiopulmonary bypass (CPB), though indispensable in many cardiac surgery procedures, has several undesirable consequences. The aim of this study was to identify potential genes that may reduce the inflammatory response and complications after CPB. The GSE132176 dataset was selected from the Gene Expression Omnibus (GEO) database and included 10 patients with tetralogy of Fallot and 10 patients with an atrial septal defect who underwent CPB surgery. TSV files were downloaded after GEO2R processing. Protein-protein interaction analysis of common differentially expressed genes (DEGs) was perfor

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Cortes, Eduardo, Ramandeep Basra, and Con J. Kelleher. "Waterbirth and pelvic floor injury: a retrospective study and postal survey using ICIQ modular long form questionnaires." European Journal of Obstetrics & Gynecology and Reproductive Biology 155, no. 1 (2011): 27–30. http://dx.doi.org/10.1016/j.ejogrb.2010.11.012.

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Marquardt, Laura M., Vanessa M. Doulames, Alice T. Wang, et al. "Designer, injectable gels to prevent transplanted Schwann cell loss during spinal cord injury therapy." Science Advances 6, no. 14 (2020): eaaz1039. http://dx.doi.org/10.1126/sciadv.aaz1039.

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Transplantation of patient-derived Schwann cells is a promising regenerative medicine therapy for spinal cord injuries; however, therapeutic efficacy is compromised by inefficient cell delivery. We present a materials-based strategy that addresses three common causes of transplanted cell death: (i) membrane damage during injection, (ii) cell leakage from the injection site, and (iii) apoptosis due to loss of endogenous matrix. Using protein engineering and peptide-based assembly, we designed injectable hydrogels with modular cell-adhesive and mechanical properties. In a cervical contusion mode

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Kumbhare, Dinesh, William Parkinson, Brett Dunlop, et al. "Biochemical Measurement of Muscle Injury Created by Lumbar Surgery." Clinical & Investigative Medicine 30, no. 1 (2007): 12. http://dx.doi.org/10.25011/cim.v30i1.444.

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Purposes: 1. To determine whether lumbar disc surgery (LS) provides a sufficiently detectable rise in serum creatine kinase (CK) concentration to serve as a model to study biochemical measurement of muscle injury, and 2. To use the model to examine the consistency of the time course of CK concentration changes.  Method: The study used a repeated measures design. Six women and six men scheduled for LS were recruited. Blood samples were taken in the pre-operative waiting areas, immediately after surgery, at 6 hour intervals until discharge, and at 2, 4, and 6 to 7 days following surgery. T

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Rahman, Muhammad Zia Ur, Imran Ali, Asif Ishfaque, et al. "Design, Analysis, and Control of Biomedical Healthcare Modular Wheelchair with Posture Transformation." Complexity 2023 (June 21, 2023): 1–13. http://dx.doi.org/10.1155/2023/7310265.

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The majority of people with disabilities in the world have impairments that affect their lower bodies. In most of these cases, it was found that the affected person’s upper body was in good health and capable of carrying out all activities; however, the spinal cord injury results in significant health challenges with body functions like urination, bowel movements, heart rate, and respiratory, cardiovascular, and sexual function, which require prompt medical treatment and mobility aids. This study presents the mechanical layout of a wheelchair that can switch between a sitting and a standing po

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Chiminello, Rita, Chiara Pellegrino, Noemi Deanesi, et al. "Bladder and Bowel Dysfunction Rehabilitation in Children with Acquired Brain Injury." Children 11, no. 11 (2024): 1382. http://dx.doi.org/10.3390/children11111382.

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Objective: To evaluate neurogenic bladder and bowel dysfunction (NBBD) in children with cerebral palsy (CP) and acquired brain injury (ABI), a condition considered less frequent in those patients than in children with spinal cord injury (SCI), and to study the relationship between NBBD and disability grade in this population. Study Design: We retrospectively reviewed the clinical data of all patients (aged 3–18 years old) admitted during a three-month observation in our neurorehabilitation department. Data collected were as follows: demographic parameters; disability status (Wee-FIM Scale, Gro

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Aljuboori, Zaid, Mayur Sharma, and Norberto Andaluz. "Contemporaneous avulsion fractures of the inferior clivus and bilateral occipital condyles with injury of the tectorial membrane." Surgical Neurology International 11 (January 17, 2020): 11. http://dx.doi.org/10.25259/sni_599_2019.

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Background: Craniocervical junction (CCJ) injuries are highly variable, and there are only limited data to suggest their optimal treatment. Here, we present a rare case of concomitant bilateral occipital condyle fractures with an inferior clival avulsion fracture with concomitant focal injury of the tectorial membrane. Case Description: Following a motor vehicle accident, a 51-year-old female sustained multiple orthopedic and soft tissue injuries. The cervical computed tomography (CT) showed a bilateral occipital condyle avulsion fractures with an avulsion of the inferior clivus. The cervical

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Han, Kihwan, Sandra B. Chapman, and Daniel C. Krawczyk. "Cognitive Training Reorganizes Network Modularity in Traumatic Brain Injury." Neurorehabilitation and Neural Repair 34, no. 1 (2019): 26–38. http://dx.doi.org/10.1177/1545968319868710.

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Background. Graph-theoretic approaches are increasingly popular for identifying the patterns of disrupted neural systems after traumatic brain injury (TBI). However, the patterns of neuroplasticity in brain organization after cognitive training in TBI are less well understood. Objective. We identified the patterns of training-induced neuroplasticity of the whole-brain network in TBI, using resting-state functional connectivity and graph theory. Methods. A total of 64 civilians and veterans with TBI were randomized into either a strategy-based cognitive training group (n = 33) or a knowledge-ba

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Gratton, Caterina, Emi M. Nomura, Fernando Pérez, and Mark D'Esposito. "Focal Brain Lesions to Critical Locations Cause Widespread Disruption of the Modular Organization of the Brain." Journal of Cognitive Neuroscience 24, no. 6 (2012): 1275–85. http://dx.doi.org/10.1162/jocn_a_00222.

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Although it is generally assumed that brain damage predominantly affects only the function of the damaged region, here we show that focal damage to critical locations causes disruption of network organization throughout the brain. Using resting state fMRI, we assessed whole-brain network structure in patients with focal brain lesions. Only damage to those brain regions important for communication between subnetworks (e.g., “connectors”)—but not to those brain regions important for communication within sub-networks (e.g., “hubs”)—led to decreases in modularity, a measure of the integrity of net

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Godson, Catherine, Patrick Guiry, and Eoin Brennan. "Lipoxin Mimetics and the Resolution of Inflammation." Annual Review of Pharmacology and Toxicology 63, no. 1 (2023): 429–48. http://dx.doi.org/10.1146/annurev-pharmtox-051921-085407.

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Inflammation and its timely resolution are critical to ensure effective host defense and appropriate tissue repair after injury and or infection. Chronic, unresolved inflammation typifies many prevalent pathologies. The key mediators that initiate and drive the inflammatory response are well defined and targeted by conventional anti-inflammatory therapeutics. More recently, there is a growing appreciation that specific mediators, including arachidonate-derived lipoxins, are generated in self-limiting inflammatory responses to promote the resolution of inflammation and endogenous repair mechani

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Smith, J. D., and A. A. West. "A modular rehabilitation system with enhanced functionality and safety to support improved recovery from injury and quality of life." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 222, no. 6 (2008): 947–58. http://dx.doi.org/10.1243/09544119jeim368.

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Wang, Jingai, Qikai Niu, Yanan Yu, et al. "Modular-Based Synergetic Mechanisms of Jasminoidin and Ursodeoxycholic Acid in Cerebral Ischemia Therapy." Biomedicines 13, no. 4 (2025): 938. https://doi.org/10.3390/biomedicines13040938.

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Objectives: Jasminoidin (JA) and ursodeoxycholic acid (UA) have been shown to exert synergistic effects on cerebral ischemia (CI) therapy, but the underlying mechanisms remain to be elucidated. Objective: To elucidate the synergistic mechanisms involved in the combined use of JA and UA (JU) for CI therapy using a driver-induced modular screening (DiMS) strategy. Methods: Network proximity and topology-based approaches were used to identify synergistic modules and driver genes from an anti-ischemic microarray dataset (ArrayExpress, E-TABM-662). A middle cerebral artery occlusion/reperfusion (MC

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Li, Jianmin, Chanyuan Pan, Chao Tang, Wenwen Tan, Hui Liu, and Jing Guan. "The Reaction Pathway of miR-30c-5p Activates Lipopolysaccharide Promoting the Course of Traumatic and Hemorrhagic Shock Acute Lung Injury." BioMed Research International 2022 (April 13, 2022): 1–7. http://dx.doi.org/10.1155/2022/3330552.

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Acute lung injury (ALI) is an acute hypoxic respiratory failure caused by diffuse inflammatory injury in alveolar epithelial cells during severe infection, trauma, and shock. Among them, trauma/hemorrhagic shock (T/HS) is the main type of indirect lung injury. Despite a great number of clinical studies, indirect factor trauma/hemorrhagic shock to the function and the mechanism in acute lung injury is not clear yet. Therefore, it is still necessary to carry on relevant analysis in order to thoroughly explore its molecular and cellular mechanisms and the pathway of disease function. In our resea

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Clark, David J., Lena H. Ting, Felix E. Zajac, Richard R. Neptune, and Steven A. Kautz. "Merging of Healthy Motor Modules Predicts Reduced Locomotor Performance and Muscle Coordination Complexity Post-Stroke." Journal of Neurophysiology 103, no. 2 (2010): 844–57. http://dx.doi.org/10.1152/jn.00825.2009.

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Evidence suggests that the nervous system controls motor tasks using a low-dimensional modular organization of muscle activation. However, it is not clear if such an organization applies to coordination of human walking, nor how nervous system injury may alter the organization of motor modules and their biomechanical outputs. We first tested the hypothesis that muscle activation patterns during walking are produced through the variable activation of a small set of motor modules. In 20 healthy control subjects, EMG signals from eight leg muscles were measured across a range of walking speeds. F

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Konishi, Hirokazu, Katsumi Miyauchi, Akira Onishi та ін. "Effect of pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor α modular (SPPARMα), in atherosclerosis model using low density lipoprotein receptor knock-out swine with balloon injury". PLOS ONE 15, № 11 (2020): e0241195. http://dx.doi.org/10.1371/journal.pone.0241195.

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Background Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that has key roles of lipid metabolism and inflammation. The PPARα may affects the initiation and progression of atherosclerosis by reducing inflammatory responses. Pemafibrate (K-877) is a novel selective PPARα modulator (SPPARMα), which was designed to possess higher PPARα potency and selectivity than existing PPARα agonists. The aim of this study is to evaluate the effect of pemafibrate on vascular response in coronary atherosclerosis model using low density lipoprotein receptor knock-out (LDLR-KO) pigs wi

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Solarino, Giuseppe, Lorenzo Moretti, Giovanni Vicenti, Davide Bizzoca, Andrea Piazzolla, and Biagio Moretti. "Hip hemiarthroplasty with modular neck: is it useful in residents’ learning curve? A prospective clinical trial." HIP International 30, no. 2_suppl (2020): 30–36. http://dx.doi.org/10.1177/1120700020964988.

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Background: The number of femoral neck fractures (FNFs) worldwide will drastically increase in the next few decades, reaching 6.3 million by 2050. In the future, therefore, newly-qualified orthopaedic surgeons will treat this kind of injury more frequently than in past decades. This prospective observational study aims to assess whether hip hemiarthroplasty with modular neck, performed via the Hardinge approach, can be safely carried out by orthopaedic residents. Methods: Patients referred to our Level I trauma centre, between January 2016 and June 2017, with displaced intra-articular femoral

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Schlage, Nana, Andreas Kitzig, Gudrun Stockmanns, and Edwin Naroska. "Development of a mobile, cost-effective and easy to use inertial motion capture system for monitoring in rehabilitation applications." Current Directions in Biomedical Engineering 7, no. 2 (2021): 586–89. http://dx.doi.org/10.1515/cdbme-2021-2149.

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Abstract Many people are familiar with the feeling of instability, pain, or subsidence in the knee joint after a knee injury. There are many different methods for examining the knee, such as the drawer test or the Lachman test [1], before and after surgery. While these tests can be used in short term and provide useful results, motion capture systems can be used as an alternative measurement method, almost as a substitute in longer term. These include marker-based or mechanica l systems, which achieve good measurement results but are expensive and inflexible. For this reason, this paper presen

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Gao, Huina, Ravindra Luhach, and Muhammed Alshehri. "International Journal of e-Collaboration (IJeC)." International Journal of e-Collaboration 19, no. 2 (2023): 1–24. http://dx.doi.org/10.4018/ijec.316660.

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In researching cognitive or motor learning aspects of activity control, motor imagery (MI) is a widely used model. Research has shown that motor imagery training can aid in memorizing motor functions because of the functional associations it shares with physical movement. Because of the high level of contact in these sports, players are more likely to sustain finger injuries. As a group of machine learning techniques, cognitive web services are designed to solve AI-related challenges. Because they are modular, cognitive web services can be easily integrated into any program, making AI more acc

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Mishra, Yashraj. "AI Human Fitness Tracker using Computer Vision with MediaPipe." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 1659–69. https://doi.org/10.22214/ijraset.2025.70547.

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In recent years, the integration of artificial intelligence (AI) into health and fitness domains has significantly enhanced personal training and physical wellness monitoring. This research introduces an AI-powered Fitness Tracker system that utilizes computer vision and pose estimation techniques to detect human body posture and accurately count repetitions or steps for various physical exercises. The system leverages MediaPipe for real-time human pose detection, computing joint angles to analyse movements and classify exercises such as push-ups, pull-ups, squats, sit-ups, and walking. It inc

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Wang, Michael Y., Daniel H. Kim, and K. Anthony Kim. "Correction of Late Traumatic Thoracic and Thoracolumbar Kyphotic Spinal Deformities Using Posteriorly Placed Intervertebral Distraction Cages." Operative Neurosurgery 62, suppl_1 (2008): ONS162—ONS172. http://dx.doi.org/10.1227/01.neu.0000317388.76185.48.

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Abstract Objective: To assess the safety and stability of thoracic or thoracolumbar deformity correction from a solely posterior approach with placement of modular anterior cages and posterior segmental fixation in one operation. Methods: Twenty-eight patients who failed brace trial for 6 months or longer were included in the series. All patients had progressive neurological deficit and/or deformity progression at time of operation. All patients underwent a single operation in the prone position. Segmental fixation was accompanied by anterior column reconstruction using modular cages avoiding

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Blackiston, Douglas, Hannah Dromiack, Caitlin Grasso, et al. "Revealing non-trivial information structures in aneural biological tissues via functional connectivity." PLOS Computational Biology 21, no. 4 (2025): e1012149. https://doi.org/10.1371/journal.pcbi.1012149.

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A central challenge in the progression of a variety of open questions in biology, such as morphogenesis, wound healing, and development, is learning from empirical data how information is integrated to support tissue-level function and behavior. Information-theoretic approaches provide a quantitative framework for extracting patterns from data, but so far have been predominantly applied to neuronal systems at the tissue-level. Here, we demonstrate how time series of Ca2+ dynamics can be used to identify the structure and information dynamics of other biological tissues. To this end, we express

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Han, Kihwan, Christine L. Mac Donald, Ann M. Johnson, et al. "Disrupted modular organization of resting-state cortical functional connectivity in U.S. military personnel following concussive ‘mild’ blast-related traumatic brain injury." NeuroImage 84 (January 2014): 76–96. http://dx.doi.org/10.1016/j.neuroimage.2013.08.017.

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Musu, Davide, Giulia Bardini, Francesca Ideo, Silvia Mezzena, and Elisabetta Cotti. "Management of the Sequelae of a Sport-Related Traumatic Dental Injury Using Ultrasound Examination in the Diagnosis and Follow-Up." Dentistry Journal 9, no. 3 (2021): 27. http://dx.doi.org/10.3390/dj9030027.

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About a quarter of all oral pathologies involving the oral cavity and dental apparatus are traumatic injuries, and a substantial number of these cases are the result of sports injuries affecting adolescents and young adults. Here, we report the case of a 25-year-old healthy female referred to the department of Endodontics for the evaluation and management of teeth 1.2 and 1.1 because of a chronic apical abscess in an area involved in a sport-related dental trauma in the past. A multi-modular diagnostic assessment, comprising conventional periapical radiographs, CBCT imaging, ultrasound, and hi

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Lukasik, Candace. "Suffering Subjects." Religion and Society 15, no. 1 (2024): 141–44. https://doi.org/10.3167/arrs.2024.150114.

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As Talal Asad elaborates in Chapter 4 of Formations of the Secular (2003), “Redeeming the ‘Human’ through Human Rights,” human rights discourse has long been criticized for failing to attend to the systematic and modular relations between violence and redress. Defining the ‘human’ in human rights is dependent upon its adjudication by independent states (or those states honoring signed treaties) and the remedies those states can supply. The ‘human’ of human rights cannot be separated from its practical translation in context. My comments on this chapter of Formations of the Secular focus on the

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