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Ji, Guangyong, Wuhong Pei, Linsheng Zhang, Rongde Qiu, Jianqun Lin, Yvonne Benito, Gerard Lina, and Richard P. Novick. "Staphylococcus intermedius Produces a Functional agr Autoinducing Peptide Containing a Cyclic Lactone." Journal of Bacteriology 187, no. 9 (May 1, 2005): 3139–50. http://dx.doi.org/10.1128/jb.187.9.3139-3150.2005.
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ABSTRACT The agr system is a global regulator of accessory functions in staphylococci, including genes encoding exoproteins involved in virulence. The agr locus contains a two-component signal transduction module that is activated by an autoinducing peptide (AIP) encoded within the agr locus and is conserved throughout the genus. The AIP has an unusual partially cyclic structure that is essential for function and that, in all but one case, involves an internal thiolactone bond between a conserved cysteine and the C-terminal carboxyl group. The exceptional case is a strain of Staphylococcus intermedius that has a serine in place of the conserved cysteine. We demonstrate here that the S. intermedius AIP is processed by the S. intermedius AgrB protein to generate a cyclic lactone, that it is an autoinducer as well as a cross-inhibitor, and that all of five other S. intermedius strains examined also produce serine-containing AIPs.
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Long, JianWu, ZeRan Yan, Lang Peng, and Tong Li. "The geometric attention-aware network for lane detection in complex road scenes." PLOS ONE 16, no. 7 (July 15, 2021): e0254521. http://dx.doi.org/10.1371/journal.pone.0254521.
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Lane detection in complex road scenes is still a challenging task due to poor lighting conditions, interference of irrelevant road markings or signs, etc. To solve the problem of lane detection in the various complex road scenes, we proposed a geometric attention-aware network (GAAN) for lane detection. The proposed GAAN adopted a multi-task branch architecture, and used the attention information propagation (AIP) module to perform communication between branches, then the geometric attention-aware (GAA) module was used to complete feature fusion. In order to verify the lane detection effect of the proposed model in this paper, the experiments were conducted on the CULane dataset, TuSimple dataset, and BDD100K dataset. The experimental results show that our method performs well compared with the current excellent lane line detection networks.
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Denham, Benjamin, Russel Pears, and Andy M. Connor. "Evaluating the Quality of Drupal Software Modules." International Journal of Software Engineering and Knowledge Engineering 28, no. 05 (May 2018): 663–700. http://dx.doi.org/10.1142/s0218194018500195.
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Evaluating software modules for inclusion in a Drupal website is a crucial and complex task that currently requires manual assessment of a number of module facets. This study applied data-mining techniques to identify quality-related metrics associated with highly popular and unpopular Drupal modules. The data-mining approach produced a set of important metrics and thresholds that highlight a strong relationship between the overall perceived reliability of a module and its popularity. Areas for future research into open-source software quality are presented, including a proposed module evaluation tool to aid developers in selecting high-quality modules.
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Wang, Hao, Yukio Ohsawa, and Yoko Nishihara. "A System Method to Elicit Innovative Knowledge Based on Chance Discovery for Innovative Product Design." International Journal of Knowledge and Systems Science 2, no. 3 (July 2011): 1–13. http://dx.doi.org/10.4018/jkss.2011070101.
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In the past few years, supplying value-added and innovative products has become an important business strategy. In this paper, a system method of innovative knowledge elicitation based on chance discovery for new product design is proposed and described. This system contains three functional modules: (1) scenario graph generation module by using Keygraph, a visual tool of chance discovery; (2) innovative knowledge solicitation module by innovators market game (IMG), a kind of table game for collaborative innovation; and (3) innovative knowledge alternatives selection module based on the method of analytic hierarchy process (AHP). The experiment is taken to play IMG and make value cognition by humans based on the scenario graph generated by Keygraph. During the IMG, innovative knowledge as new value is co-created by humans. AHP is used to evaluate these innovative alternatives. The performance of the method is illustrated by using a case study on innovative product design. The results indicate this method can aid humans in eliciting innovative knowledge for creative product design at the early stage of product development.
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Rahro Zargar, Majid, and Hossein Zakeri. "On Flat and Gorenstein Flat Dimensions of Local Cohomology Modules." Canadian Mathematical Bulletin 59, no. 2 (June 1, 2016): 403–16. http://dx.doi.org/10.4153/cmb-2015-080-x.
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AbstractLet a be an ideal of a Noetherian local ring R and let C be a semidualizing R-module. For an R-module X, we denote any of the quantities fdR X, GfdR X and GC-fdR X by T(X). Let M be an R-module such that for all i ≠ n. It is proved that if T(M) < ∞, then , and the equality holds whenever M is finitely generated. With the aid of these results, among other things, we characterize Cohen–Macaulay modules, dualizing modules, and Gorenstein rings.
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Manurung, Sondang R., Mara Bangun Harahap, Nuryani Y. Rustaman, and Benny Suprapto Brotosiswoyo. "IMPLEMENTATION OF QUANTUM PHYSICS INTRODUCTION AID ON VIRTUAL LABORATORIES TO IMPROVE PROFICIENCY GENERIC." Jurnal Kependidikan: Penelitian Inovasi Pembelajaran 2, no. 2 (November 30, 2018): 382–94. http://dx.doi.org/10.21831/jk.v2i2.15136.
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This study was aimed at determining the results of virtual laboratory implementation in the introduction of quantum physics in improving the generic proficiency of prospective teacher students. The research method used was quasi-experimental with pretest-posttest control group design. This design uses the determination of equivalent subjects between the experimental group and purposive control. This learning module consists of 2 types, namely computer program aided module that display the visualization of quantum physics symptoms and conventional learning modules. This study was carried out on a teacher training institution in Bandung, West Java. The research subjects were the sixth semester students of Physics Education in the Subject of Quantum Physics, year 2014/2015. The sample in the experimental group consisted of 15 students, while the control group consisted of 24 students. The experimental group students received the learning of quantum physics with a virtual laboratory, while the control group received conventional learning. The result shows that the use of virtual laboratories in the introduction of quantum physics is able to improve the generic skills of students.IMPLEMENTASI LABORATORIUM VIRTUAL DALAM PEMBELAJARAN PENDAHULUAN FISIKA KUANTUM UNTUK MENINGKATKAN KEMAHIRAN GENERIKAbstrakPenelitian ini bertujuan untuk mengetahui hasil implementasi laboratorium virtua dalam pembelajaran Pendahuluan Fisika kuantum dalam meningkatkan kemahiran generik mahasiswa calon guru. Metode penelitian adalah eksperimen semu dengan pretest-posttest Control Group Design. Desain ini menggunakan penetapan subjek setara antara kelompok eksperimen dan kontrol secara purposif. Modul pembelajaran ini terdiri dari 2 jenis yakni modul yang mempergunakan program komputer yang menampilkan visualisasi gejala fisika kuantum dan modul pembelajaran konvensional. Penelitian ini dilaksanakan di LPTK di Kota Bandung Jawa Barat dengan subjek penelitian mahasiswa Semester VI Jurusan Pendidikan Fisika pada Mata Kuliah Fisika Kuantum Tahun Akademik 2014/2015. Sampel penelitian dalam kelompok eksperimen terdiri dari 15 orang mahasiswa. Kelompok kontrol terdiri dari 24 orang mahasiswa. Mahasiswa kelompok eksperimen menerima pembelajaran fisika kuantum dengan laboratorium virtual. Kelompok kontrol menerima pembelajaran konvensional. Hasil penelitian menunjukkan bahwa penggunaan laboratorium virtual dalam pembelajaran pendahuluan fisika kuantum dapat meningkatkan kemahiran generik mahasiswa.
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Lin, Wen Guang, Liang Hou, Rong Shen Lai, Yong Ming Wu, and Wei Huang. "Method to Aid Modules Innovation by Patent Knowledge." Advanced Materials Research 468-471 (February 2012): 1931–35. http://dx.doi.org/10.4028/www.scientific.net/amr.468-471.1931.
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According to the innovation of specific module during the process of product platform in innovation and evolution, a method of using patent knowledge for aiding modules innovation based on axiomatic design and TRIZ was put forward. Firstly, we design the model of innovative design of module based on patent. On this basis, we construct the process of patent circumvent based on axiomatic design and TRIZ, and the conceptual design method based on patent knowledge of same field. Finally, application of the method was illustrated by example to verify the effectiveness.
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Watanapa, Bunthit, Orasa Patsadu, Piyapat Dajpratham, and Chakarida Nukoolkit. "Post-Fall Intelligence Supporting Fall Severity Diagnosis Using Kinect Sensor." Applied Computational Intelligence and Soft Computing 2018 (June 3, 2018): 1–15. http://dx.doi.org/10.1155/2018/5434897.
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This paper proposes a fall severity analytic and post-fall intelligence system with three interdependent modules. Module I is the analysis of fall severity based on factors extracted in the phases of during and after fall which include innovative measures of the sequence of body impact, level of impact, and duration of motionlessness. Module II is a timely autonomic notification to relevant persons with context-dependent fall severity alert via electronic communication channels (e.g., smartphone, tablet, or smart TV set). Lastly, Module III is the diagnostic support for caregivers and doctors to have information for making a well-informed decision of first aid or postcure with the chronologically traceable intelligence of information and knowledge found in Modules I and II. The system shall be beneficial to caregivers or doctors, in giving first aid/diagnosis/treatment to the subject, especially, in cases where the subject has lost consciousness and is unable to respond.
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Rudlof, Peter. "On Minimax and Related Modules." Canadian Journal of Mathematics 44, no. 1 (February 1, 1992): 154–66. http://dx.doi.org/10.4153/cjm-1992-009-7.
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AbstractA module M is called a minimax module, if it has a finitely generated submodule U such that M/U is Artinian. This paper investigates minimax modules and some generalized classes over commutative Noetherian rings. One of our main results is: M is minimax iff every decomposition of a homomorphic image of M is finite.From this we deduce that:- All couniform modules are minimax.- All modules of finite codimension are minimax.- Essential covers of minimax modules are minimax. With the aid of these corollaries we completely determine the structure of couniform modules and modules of finite codimension.We then examine the following variants of the minimax property:- replace U “ finitely generated” by U “ coatomic” (i.e. every proper submodule of U is contained in a maximal submodule);- replace M/U “ Artinian” by M/U “ semi-Artinian” (i.e. every proper submodule of M/U contains a minimal submodule).
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Wang, Meng, Jian Qiang Wu, and Xiao Hua Zhang. "A Self-Adaptive BMS Based on CAN-Bus for Power Li-Ion Battery." Applied Mechanics and Materials 130-134 (October 2011): 3553–56. http://dx.doi.org/10.4028/www.scientific.net/amm.130-134.3553.
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A self-adaptive battery management system (BMS) based on CAN-bus for power Li-ion battery was designed in this paper. It is designed distributed and composed of sampling modules, a master module and some aid devices. The sampling module is used to sampling the voltage of the cells and the temperature in the pack. And it keeps the temperature in safe range by controlling the fans in the pack. The master module receives the information from the sampling modules, samples the current of the main road, estimates the state of charge (SOC), the state of health (SOH), controls the main road relays. The modules communicate with each other by CAN-bus. The fault and temperature management are performed adaptively. It is shown that this self-adaptive BMS extend the battery lifetime and guarantee safe operation. And the self-power consumption is very low.
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Zeng, Wei Liang. "Research on Teaching Aid of Analog Circuits Based on Magnetic Element." Applied Mechanics and Materials 624 (August 2014): 373–76. http://dx.doi.org/10.4028/www.scientific.net/amm.624.373.
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In the traditional teaching process of analog circuit course, the connected circuit element and current trend are not intuitive and students understand difficultly. In order to solve this problem, the teaching aid of analog circuit based on magnetic elements is researched and designed, including a DC power supply, some element modules and some connecting soft lights, both ends of the connecting soft light has a connecting plug connection, element module is comprised of bottom plate, switch, socket, input slot, output slot, symbol and permanent magnet, input slot and output slot are communicated together , switch and symbol are communicated together, permanent magnet is located at the bottom of the component module. By a plurality of component modules absorbed on the surface of iron blackboard that are marked with the symbol to make up the teaching circuit, by shining of connecting soft lights to simulate the current in the circuit, the teaching content of analog circuit is vividly demonstrated and understanding of students for teaching content is improved.
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Hai, Ling Ying, Xinjiletu Yang, and Wei Hong Han. "A Study on the Index System for Evaluating Low Carbon Economy of Resource-Based Region Based on AHP." Advanced Materials Research 869-870 (December 2013): 935–41. http://dx.doi.org/10.4028/www.scientific.net/amr.869-870.935.
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In accordance with the principles and AHP method, this research proposed an evaluation index system which is appropriate for resource based regions. The index system includes four modules---low carbon industry module, low carbon society module, low carbon environment module, low carbon technology module and characteristics of resource module that contains 23 specific indicators. Then it applied the system to three typical resource-based regions--Inner Mongolia Province, Shanxi Province, Heilongjiang Province. Lastly, according to the work above, this article put forward proposals that could do help to develop low-carbon economy of resource-based regions. They are expanding the industrial chain as well as industry exit mechanism, establishing mechanisms for cooperation among the resource-based regions to develop and apply low carbon technologies actively and adjusting income distribution system to reducing the income gap between urban and rural areas of resource-based regions.
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Cary, Michael, Katie Podshivalova, and Cynthia Kenyon. "Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans’ Gene Expression Data." G3: Genes|Genomes|Genetics 10, no. 10 (August 5, 2020): 3623–38. http://dx.doi.org/10.1534/g3.120.401270.
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Identification of co-expressed sets of genes (gene modules) is used widely for grouping functionally related genes during transcriptomic data analysis. An organism-wide atlas of high-quality gene modules would provide a powerful tool for unbiased detection of biological signals from gene expression data. Here, using a method based on independent component analysis we call DEXICA, we have defined and optimized 209 modules that broadly represent transcriptional wiring of the key experimental organism C. elegans. These modules represent responses to changes in the environment (e.g., starvation, exposure to xenobiotics), genes regulated by transcriptions factors (e.g., ATFS-1, DAF-16), genes specific to tissues (e.g., neurons, muscle), genes that change during development, and other complex transcriptional responses to genetic, environmental and temporal perturbations. Interrogation of these modules reveals processes that are activated in long-lived mutants in cases where traditional analyses of differentially expressed genes fail to do so. Additionally, we show that modules can inform the strength of the association between a gene and an annotation (e.g., GO term). Analysis of “module-weighted annotations” improves on several aspects of traditional annotation-enrichment tests and can aid in functional interpretation of poorly annotated genes. We provide an online interactive resource with tutorials at http://genemodules.org/, in which users can find detailed information on each module, check genes for module-weighted annotations, and use both of these to analyze their own gene expression data (generated using any platform) or gene sets of interest.
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Li, Yiyang, and Bin Shu. "Filtrations in Modular Representations of Reductive Lie Algebras." Algebra Colloquium 17, no. 02 (June 2010): 265–82. http://dx.doi.org/10.1142/s1005386710000283.
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Let G be a connected reductive algebraic group over an algebraically closed field k of prime characteristic p, and 𝔤 = Lie (G). In this paper, we study representations of the reductive Lie algebra 𝔤 with p-character χ of standard Levi form associated with an index subset I of simple roots. With aid of the support variety theory, we prove that a Uχ(𝔤)-module is projective if and only if it is a strong "tilting" module, i.e., admitting both [Formula: see text]- and [Formula: see text]-filtrations. Then by an analogy of the arguments in [2] for G1T-modules, we construct so-called Andersen–Kaneda filtrations associated with each projective 𝔤-module of p-character χ, and finally obtain sum formulas from those filtrations.
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Palconit, E. V., and M. L. S. Abundo. "Electric Ferry Ecosystem for Sustainable Inter-Island Transport in Philippines: A Pilot Study." Engineering, Technology & Applied Science Research 8, no. 6 (December 22, 2018): 3570–75. http://dx.doi.org/10.48084/etasr.2382.
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An electric boat system as a pilot study for the electric ferry was designed and field-tested in Samal Island, Philippines, to verify sustainability for inter-island transport. This pilot study uses 4.5m monohull with a displacement weight of 343kg. During the experiment, two cases were compared: in the first case the boat was powered solely with batteries and in the other case with the aid of photovoltaic (PV) modules. For the first case, 24V electric propulsion was driven by two 12V, 100Ah batteries, which resulted to a navigational range of around 18, 16 and 15 trips with energy consumption of 111.64Wh, 117.19Wh and 123.92Wh respectively. In the second case, the photovoltaic modules were attached on the boat to supplement the PV used while on sail. Results in the second case showed that PV module supplemented energy was about to 13.4%, 26.8% and 38.7% using three different speeds like 3.18, 3.32 and 3.84knots and the navigational range extended to 4km, 1km, and 14.4km respectively. Therefore, the electric boat with the aid of PV module answers the problem in the energy management system that deals with the sustainability of the system in the inter-island transport in Philippines.
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Xu, Xiao Wen, and Jin Yi He. "Design of Intelligent Guide Vehicle for Blind People." Applied Mechanics and Materials 268-270 (December 2012): 1490–93. http://dx.doi.org/10.4028/www.scientific.net/amm.268-270.1490.
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Traditionally, guide dogs are used as a travel aid for blind people. But they cannot be popularized because the training cost for guide dogs is quite high. This paper presents an intelligent guide vehicle prototype for blind people. The system is developed by using ARM as a controller and processor, via integration of ultrasonic detection and photoelectric detection technology, aiming at automatically navigation for blind people. This system mainly consists of four modules, which are ultrasonic detection module, photoelectric detection module, voice prompt module and automatic control module. The signal reflected by roadblock on the road can be detected by ultrasonic detection module which can work out distance between roadblock and guide vehicle. The aim of photoelectric detection module is to realize the function of road recognition and tracking. Voice prompt module can provide information of distance of roadblock. Strategies of obstacle avoidance were taken to the blind when the guide vehicle is going to avoid roadblock. If the roadblock is less than 50cm away, the automatic control module will automatically set the guide vehicle to avoid obstacles. Preliminary experimental results show that users can control and navigate with the intelligent guide vehicle.
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Wang, Cai Xia, and Ning Liu. "The Algorithm of Case-Searching Based on AHP Application." Applied Mechanics and Materials 513-517 (February 2014): 2416–19. http://dx.doi.org/10.4028/www.scientific.net/amm.513-517.2416.
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The knowledge management system of teaching case corpus adopts case reasoning technology in the field of artificial intelligence. The whole system includes altogether ten modules. They are case uploading, case modification, case analysis, case algorithm and critical case management. The basic function is to assist the trained teachers to get the teaching case knowledge from other teachers, so as to develop teachersspecialty. In the module of case algorithm , in the application of the algorithm of case-searching based on AHP, the case needed by the users can be sorted out in an objective and fair way.
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Jo̸rgensen, Martin Bondo, and Karsten Videbæk. "Miniature hearing aid insert module." Journal of the Acoustical Society of America 125, no. 1 (2009): 582. http://dx.doi.org/10.1121/1.3074472.
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Melis, A., R. Chiello, G. Comoretto, R. Concu, A. Magro, G. Naldi, A. Navarrini, et al. "A Digital Beamformer for the PHAROS2 Phased Array Feed." Journal of Astronomical Instrumentation 09, no. 03 (September 2020): 2050013. http://dx.doi.org/10.1142/s2251171720500130.
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PHased Arrays for Reflector Observing Systems (PHAROS) is a C-band (4–8[Formula: see text]GHz) Phased Array Feed (PAF) receiver designed to operate from the primary focus of a large single-dish radio astronomy antenna. It consists of an array of 220-element Vivaldi antennas ([Formula: see text] polarization), cryogenically cooled at roughly 20[Formula: see text]K along with low noise amplifiers (LNAs), and of analogue beamformers cryogenically cooled at roughly 80[Formula: see text]K. PHAROS2, the upgrade of PHAROS, is a PAF demonstrator developed in the framework of the Square Kilometer Array Advanced Instrumentation Program (SKA AIP) with the goal of investigating the potential of the PAF technologies at high frequencies in view of their possible application on the SKA dish telescopes. The PHAROS2 design includes new cryogenically cooled LNAs with state-of-the-art performance, a digital beamformer capable of synthesizing four beams from a sub-array of 24 single-polarization antenna elements, and a C-band multi-channel Warm Section receiver capable of analogue filtering and down-converting the signals from the antennas to a suitable frequency range at the input of the digital backend, providing an instantaneous bandwidth of 275[Formula: see text]MHz for each signal. In this paper, we describe the design and performance of the PHAROS2 digital backend/beamformer, based on the Italian Tile Processing Module (ITPM) hardware, which was initially developed for the SKA Low Frequency Aperture Array (LFAA). The backend was adapted to perform the beamforming for our PAF application. We describe the implementation of the beamformer on the Field Programmable Gate Arrays (FPGAs) of the ITPM and how the backend was successfully used to synthesize four independent beams, both in the laboratory (across the entire 275[Formula: see text]MHz instantaneous bandwidth) and during on-field observations at the BEST-2 array (across 16[Formula: see text]MHz instantaneous bandwidth), which is a subset of the Northern Cross Radio Telescope (located in the district of Bologna, Italy). The beamformer design allows re-scaling to a greater number of beams and wider bandwidths.
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Ortega, S., M. R. Soler, J. Beneito, and D. Pino. "Evaluation of two ozone air quality modelling systems." Atmospheric Chemistry and Physics 4, no. 5 (August 25, 2004): 1389–98. http://dx.doi.org/10.5194/acp-4-1389-2004.
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Abstract. The aim of this paper is to compare two different modelling systems and to evaluate their ability to simulate high values of ozone concentration in typical summer episodes which take place in the north of Spain near the metropolitan area of Barcelona. As the focus of the paper is the comparison of the two systems, we do not attempt to improve the agreement by adjusting the emission inventory or model parameters. The first model, or forecasting system, is made up of three modules. The first module is a mesoscale model (MASS). This provides the initial condition for the second module, which is a nonlocal boundary layer model based on the transilient turbulence scheme. The third module is a photochemical box model (OZIPR), which is applied in Eulerian and Lagrangian modes and receives suitable information from the two previous modules. The model forecast is evaluated against ground base stations during summer 2001. The second model is the MM5/UAM-V. This is a grid model designed to predict the hourly three-dimensional ozone concentration fields. The model is applied during an ozone episode that occurred between 21 and 23 June 2001. Our results reflect the good performance of the two modelling systems when they are used in a specific episode.
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Whitten, Andrew E., Shuzhi Cai, and Jill Trewhella. "MULCh: modules for the analysis of small-angle neutron contrast variation data from biomolecular assemblies." Journal of Applied Crystallography 41, no. 1 (January 16, 2008): 222–26. http://dx.doi.org/10.1107/s0021889807055136.
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Small-angle neutron scattering with contrast variation can fill important gaps in our understanding of biomolecular assemblies, providing constraints that can aid in the construction of molecular models and in subsequent model refinements. This paper describes the implementation of simple tools for analysing neutron contrast variation data, accessibleviaa user-friendly web-based interface (http://www.mmb.usyd.edu.au/NCVWeb/). There are three modules accessible from the website to analyse neutron contrast variation data from bimolecular complexes. The first module,Contrast, computes neutron contrasts of each component of the complex required by the other two modules; the second module,Rg, analyses the contrast dependence of the radii of gyration to yield information relating to the size and disposition of each component in the complex; and the third,Compost, decomposes the contrast variation series into composite scattering functions, which contain information regarding the shape of each component of the complex, and their orientation with respect to each other.
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CHARAFI, MY M., A. SADOK, A. KAMAL, and A. MENAI. "NUMERICAL MODELING OF WATER CIRCULATION AND POLLUTANT TRANSPORT IN A SHALLOW BASIN." International Journal of Modern Physics C 11, no. 04 (June 2000): 655–64. http://dx.doi.org/10.1142/s0129183100000572.
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A two-dimensional numerical model was developed1–3 to simulate the sediment and pollutant transport in a shallow basin. The developed model consist of two modules: Hydrodynamic module and sediment/pollutant transport module. A numerical hydrodynamic module based on the Saint-Venant equations, is resolved by a MacCormack numerical scheme and is used to simulate the circulation pattern in the basin. The obtained flow circulation is used as an input to the sediment/pollutant transport module to simulate the transport and dispersion of a pollutant emitted into the basin. To calibrate the numerical model, the distorted scale model of the Windermere Basin4 was used. In this physical model, the flow visualization and pollutant transport experiments provide a good calibration. The simulated results were found to be in good agreement with the experimental measurements and the results in Ref. 4. With the aid of the validated model, the influence of the construction of dikes on the residence time distributions in the basin was examined.
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Kabeil, Magdy M. "A Proposed Framework for Developing a National Crisis Management Information System." International Journal of Information Systems for Crisis Response and Management 1, no. 4 (October 2009): 50–74. http://dx.doi.org/10.4018/jiscrm.2009071004.
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A conceptual design representing basic modules of National Crisis Management Information System NCMIS is developed. The conceptual design provides a general foundation that can be transferred to a detailed design and implementation of an application. The concept of NCMIS meets the initial specifications that are validated using a case scenario. The relative percentage of the total score that each module contributes to the design is evaluated using the Analytical Hierarchy Process AHP and the Quality Function Deployment QFD technique.
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Herguedas, Beatriz, Isaias Lans, María Sebastián, Juan A. Hermoso, Marta Martínez-Júlvez, and Milagros Medina. "Structural insights into the synthesis of FMN in prokaryotic organisms." Acta Crystallographica Section D Biological Crystallography 71, no. 12 (November 27, 2015): 2526–42. http://dx.doi.org/10.1107/s1399004715019641.
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Riboflavin kinases (RFKs) catalyse the phosphorylation of riboflavin to produce FMN. In most bacteria this activity is catalysed by the C-terminal module of a bifunctional enzyme, FAD synthetase (FADS), which also catalyses the transformation of FMN into FAD through its N-terminal FMN adenylyltransferase (FMNAT) module. The RFK module of FADS is a homologue of eukaryotic monofunctional RFKs, while the FMNAT module lacks homologyto eukaryotic enzymes involved in FAD production. Previously, the crystal structure ofCorynebacterium ammoniagenesFADS (CaFADS) was determined in its apo form. This structure predicted a dimer-of-trimers organization with the catalytic sites of two modules of neighbouring protomers approaching each other, leading to a hypothesis about the possibility of FMN channelling in the oligomeric protein. Here, two crystal structures of the individually expressed RFK module ofCaFADS in complex with the products of the reaction, FMN and ADP, are presented. Structures are complemented with computational simulations, binding studies and kinetic characterization. Binding of ligands triggers dramatic structural changes in the RFK module, which affect large portions of the protein. Substrate inhibition and molecular-dynamics simulations allowed the conformational changes that take place along the RFK catalytic cycle to be established. The influence of these conformational changes in the FMNAT module is also discussed in the context of the full-lengthCaFADS protomer and the quaternary organization.
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Gorane, Shrikant, and Ravi Kant. "A case study for predicting the success possibility of supply chain practices implementation using AHP approach." Journal of Business & Industrial Marketing 31, no. 2 (March 7, 2016): 137–51. http://dx.doi.org/10.1108/jbim-05-2014-0098.
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Purpose – The purpose of this paper is to predict the success possibility of supply chain practices (SCPs) implementation based on ten selected SCPs using the analytic hierarchy process (AHP). Design/methodology/approach – A case study was conducted, and for the same, data were collected from two organizations. The data collected from both the organizations were analyzed using AHP. The pair-wise comparisons of SCPs (usually, alternatives and attributes) are established using a scale indicating the strength with which one SCP dominates another with respect to higher-level SCPs. This scaling process then translated into priority weights. Once the priority weights of the elements/determinants of the module have been calculated, the presence of the corresponding element in the organization was evaluated. An evaluation rating of these elements multiplied by the established priority weights have determined the prediction weight for each SCP. Findings – The application of this procedure is described for the institutionalization module and can be similarly extended to the other SCPs/SCM implementation modules. By establishing the prediction weight for each module, the organizations will be able to evaluate the strength of the corresponding factors present before embarking on the SCPs. The organization can identify and create awareness of the essential elements in the SCPs implementation process and identify the actions necessary before implementing SCPs. The AHP can be a useful guide in the decision-making process of SCPs implementation, especially for medium- and large-scale organizations. Research limitations/implications – The priority weights are subjective and assigned as per the judgment of SCM managers from both the organizations. Further, the priority weights can be obtained from more industry experts through a questionnaire. Second, in this model, only ten practices are taken into consideration for successful SCPs implementation; more practices may be included in future research. Practical implications – The methodological approach presented can be a useful guide in the decision-making process of SCPs implementation in an organization. The outcome will aid practitioners to know the SCPs and benchmark the organizations on the basis of the methodological research conducted. Again, this model can simply act as a possible research model and the data can act as an example that can be utilized for other studies. Originality/value – This is the first kind of study which identified ten SCPs and further deployed AHP approach to see the success possibility of combined SCPs that influence the SCM implementation in an organization.
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Passilly, Bruno, Benjamin Lamboul, and Jean-Michel Roche. "Indentation haute fréquence : vers le contrôle non-destructif des structures." Matériaux & Techniques 105, no. 1 (2017): 110. http://dx.doi.org/10.1051/mattech/2017026.
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La nanoindentation est couramment utilisée pour déterminer les propriétés mécaniques locales des matériaux. La matière est sollicitée de façon quasi statique en appliquant un indenteur sur la surface à analyser. À partir de la courbe représentant la charge appliquée par l’indenteur sur le matériau en fonction du déplacement de l’indenteur, les modèles classiques permettent de déterminer le module d’Young local en tout point de test [Oliver & Pharr, AIP Conference proceedings 7 (1992) 1564-1583; Doerner & Nix, J. Mater. Res. 1 (1986) 601-609; Loubet et al., Vickers indentation curves of elastoplastic materials, in American Society for Testing and Materials STP 889, Microindentation Techniques in Materials Science and Engineering, Blau & Lawn eds, 1986, pp. 72-89]. Cet essai est surtout utilisé sur de petites surfaces de matière (<1 cm2), qui doivent présenter un état de surface poli et plan afin de ne pas fausser la mesure, mais n’est pas adapté sur des pièces de structure de type tôle ou sandwich composite (>1000 cm2). Par extension de la méthode CSM (Continuous Stiffness Measurement) [Asif et al., Rev. Sci. Instrum. 70 (1999) 2408-2413], l’indenteur peut servir de générateur de vibrations. Pour cela l’indenteur est positionné sur un empilement de céramiques piézoélectriques et est appliqué sur la surface à analyser à une charge fixe de 1000 mN. L’indenteur est soumis à une oscillation à une fréquence de 5 kHz, alimenté à 10 V. Les ondes ultrasonores ainsi générées, dites «ondes de Lamb», induisent un déplacement nanométrique de la surface, détectable par un vibromètre laser. Il est alors possible de suivre la propagation du front d’onde et de détecter ses interactions avec d’éventuels défauts de la structure inspectée [Boro Djordjevic, Quantitative ultrasonic guided wave testing of composites, The 39th Annual Review of Progress, 2013]. Il en résulte une cartographie complète de la surface. L’indenteur peut aussi être utilisé comme récepteur de l’onde générée. Le positionnement d’indenteurs récepteurs en plusieurs endroits de la structure permet de mesurer le temps de vol de l’onde entre l’indenteur émetteur et l’indenteur récepteur. La connaissance précise de la distance entre les points d’émission et de réception de l’onde permet de mesurer les vitesses en fonction de l’anisotropie du matériau, ce qui, à terme, peut permettre de remonter à ses constantes d’élasticité.
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Switzer, Benjamin, Khalid Jazieh, Eden Bernstein, and David Harris. "Impact of an Electronic Medical Record Alert on Code Status Documentation for Hospitalized Patients With Advanced Cancer." JCO Oncology Practice 16, no. 3 (March 2020): e257-e263. http://dx.doi.org/10.1200/jop.19.00408.
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PURPOSE: Cardiopulmonary resuscitation in hospitalized patients with advanced cancer is associated with high rates of morbidity and mortality. Although advance care planning (ACP) in this population improves quality, patient satisfaction, hospice use, rates of harm, and health care costs, ACP documentation rates remain low. We observed changes in ACP documentation by internal medicine residents within a tertiary hospital’s inpatient oncology service after a mandatory training module and enterprise-wide modification in electronic health medical records (EHMR). METHODS: For patients admitted to the Cleveland Clinic oncology service, this 16-week retrospective review observed resident code status (CS) documentation through admission notes and direct EHMR orders before and after implementation of an ACP training module and CS best practice alert (BPA). In addition, residents were surveyed on perceived barriers to CS documentation. RESULTS: In 535 unique admissions (244 before BPA, 291 after BPA), residents exhibited a 14.4% increase (from 47.1% to 61.5%) in admission note CS documentation and an 18.2% increase (from 12.7% to 30.9%) in CS orders at time of discharge. The most common self-reported barrier to ACP documentation was forgetting to discuss, with first-, second-, and third-year residents admitting to feeling uncomfortable in orchestrating ACP conversations at rates of 58%, 6%, and 5%, respectively. CONCLUSION: Resident ACP documentation remains suboptimal in the high-risk cohort of hospitalized patients with advanced cancer. However, rates seem to be positively influenced by online modules and EHMR-based interventions. Additional efforts to improve the current practice and culture of ACP remain a crucial aspect in the quality and safety of our approach to patient care.
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Niederdränk, Torsten. "Acoustic module for a hearing aid device." Journal of the Acoustical Society of America 125, no. 1 (2009): 582. http://dx.doi.org/10.1121/1.3074471.
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Özkan, Ramazan, and Mustafa Serdar Genç. "Multi-objective structural optimization of a wind turbine blade using NSGA-II algorithm and FSI." Aircraft Engineering and Aerospace Technology 93, no. 6 (July 13, 2021): 1029–42. http://dx.doi.org/10.1108/aeat-02-2021-0055.
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Purpose Wind turbines are one of the best candidates to solve the problem of increasing energy demand in the world. The aim of this paper is to apply a multi-objective structural optimization study to a Phase II wind turbine blade produced by the National Renewable Energy Laboratory to obtain a more efficient small-scale wind turbine. Design/methodology/approach To solve this structural optimization problem, a new Non-Dominated Sorting Genetic Algorithm (NSGA-II) was performed. In the optimization study, the objective function was on minimization of mass and cost of the blade, and design parameters were composite material type and spar cap layer number. Design constraints were deformation, strain, stress, natural frequency and failure criteria. ANSYS Composite PrepPost (ACP) module was used to model the composite materials of the blade. Moreover, fluid–structure interaction (FSI) model in ANSYS was used to carry out flow and structural analysis on the blade. Findings As a result, a new original blade was designed using the multi-objective structural optimization study which has been adapted for aerodynamic optimization, the NSGA-II algorithm and FSI. The mass of three selected optimized blades using carbon composite decreased as much as 6.6%, 11.9% and 14.3%, respectively, while their costs increased by 23.1%, 29.9% and 38.3%. This multi-objective structural optimization-based study indicates that the composite configuration of the blade could be altered to reach the desired weight and cost for production. Originality/value ACP module is a novel and advanced composite modeling technique. This study is a novel study to present the NSGA-II algorithm, which has been adapted for aerodynamic optimization, together with the FSI. Unlike other studies, complex composite layup, fiber directions and layer orientations were defined by using the ACP module, and the composite blade analyzed both aerodynamic pressure and structural design using ACP and FSI modules together.
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Wang, Yan, Xiangyang Zhang, Min Duan, Chenguang Zhang, Ke Wang, Lili Feng, Linlin Song, Sheng Wu, and Xuyan Chen. "Identification of Potential Biomarkers Associated with Acute Myocardial Infarction by Weighted Gene Coexpression Network Analysis." Oxidative Medicine and Cellular Longevity 2021 (August 27, 2021): 1–11. http://dx.doi.org/10.1155/2021/5553811.
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Background. In the general population, acute myocardial infarction (AMI) represents a significant cause of mortality. This study is aimed at identifying novel diagnostic biomarkers to aid in treating and diagnosing AMI. Methods. The Gene Expression Omnibus (GEO) database was explored to extract two microarray datasets, GSE66360 and GSE48060, which were subsequently merged into a single cohort. Both AMI and control samples were analyzed for differentially expressed genes (DEGs), which were subsequently subjected to weighed gene coexpression network analysis (WGCNA) to identify the most significant module. Gene Ontology (GO) and pathway analyses subsequently carried out the most significant gene modules along with construction of a protein-protein interaction network (PPI). Cytoscape plugin cytoHubba allowed for the prediction of the top 4 key genes according to the network maximal clique centrality (MCC) algorithm. The expression levels and diagnostic value of the four key genes were additionally verified in the GSE62646 dataset. Results. A WCGNA analysis revealed 878 DEGs which were clustered into 6 modules. The module with the most significance in AMI was colored blue. Subsequent GO and KEGG pathway enrichment analysis on blue module genes revealed that they were primarily enriched in the inflammation-related pathways. These findings, in combination with PPI and coexpression networks, resulted in the identification of the top four genes by cytoHubba, which included leukocyte immunoglobulin-like receptor B2 (LILRB2), toll-like receptor 2 (TLR2), neutrophil cytosolic factor 2 (NCF2), and S100A9. Among them, LILRB2, NCF2, and S100A9 were validated in the GSE62646 dataset. Conclusions. The results suggested that LILRB2, NCF2, and S100A9 could be potential gene biomarkers for AMI.
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Davison, Jack, Jonathan Dorival, Hery Rabeharindranto, Hortense Mazon, Benjamin Chagot, Arnaud Gruez, and Kira Weissman. "Function of polyketide synthases from the SAXS structure of a complete module." Acta Crystallographica Section A Foundations and Advances 70, a1 (August 5, 2014): C407. http://dx.doi.org/10.1107/s2053273314095928.
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The modular polyketide synthases (PKS), common to many bacterial antibiotic-producers, are huge multienzyme, multidomain systems which can be likened to molecular assembly lines.1 An understanding of the structural and mechanistic aspects which underpin interdomain cooperation during biosynthesis by modular PKS is crucial to ongoing efforts to re-engineer these systems for the production of novel compounds of medicinal value.2 Previous attempts to solve the structures of PKS modules by X-ray crystallography have been unsuccessful, likely due to the high, inherent flexibility of the multienzymes. Here, we have employed an alternative technique, small-angle X-ray scattering (SAXS), in combination with NMR structure elucidation and homology modelling of individual domains, to obtain the first low-resolution structural data on an entire apo PKS module. The model system comprises a multidomain region of the virginiamycin M1 PKS from Streptomyces virginiae, a target of relevance for its involvement in production of the commercial antibiotic dalfopristin. The investigated region, which comprises a ketosynthase (KS) and two consecutive acyl carrier protein (ACP) domains, interacts with a wide range of protein partners, including notably, a complex of discrete enzymes responsible for β-methylation of the polyketide, and the N-terminus of the downstream PKS protein, VirFG.3 In our solved structure (Fig. 1), the homodimeric KS, which is flanked by well-folded linker regions, occupies the center of the module. While the first ACP is located close to the KS, the second is situated at the end of a flexible linker, and mobile. Taken together, these data provide a physical explanation for the functional non-equivalence previously observed for certain tandem ACPs of this class of PKS. Furthermore, the overall open shape of the module renders the second ACP highly accessible, which may be critical for its interaction with its multiple in trans catalytic partners. Finally, our analysis redefines the function of a putative dimerization motif of tandem ACPs as a docking domain, suggesting that the module likely adopts a more closed form in order to affect transfer of the chain extension intermediate to the subsequent module.
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PETTENGHI, HECTOR, SORIN COTOFANA, and LEONEL SOUSA. "EFFICIENT METHOD FOR DESIGNING MODULO {2n ± k} MULTIPLIERS." Journal of Circuits, Systems and Computers 23, no. 01 (January 2014): 1450001. http://dx.doi.org/10.1142/s0218126614500017.
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In this paper, an efficient method for designing memoryless modulo {2n ± k} multipliers is proposed, which can be used to compose larger residue number system (RNS) moduli sets. This technique includes a novel choice for the weights associated with the partial products of the inputs is used, which improves the performance of the resulting multipliers. Experimental results suggest that the use of this choice of input weights in the structure herein proposed, provides an average improvement of 36.3% in area-delay-product (ADP) in comparison with the related state-of-the-art. Furthermore, the structures presented in the state-of-the-art are also improved by 43.5% in ADP.
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Rani, Latifah, and Samsul Maarif. "Development E-Module Three Variables Linear Equations System Based On Mathematic Communication." Journal of Medives : Journal of Mathematics Education IKIP Veteran Semarang 5, no. 2 (July 19, 2021): 377. http://dx.doi.org/10.31331/medivesveteran.v5i2.1707.
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This rapid technological development has a very significant impact on various aspects of human life, one of which is in the aspect of education. The existence of technological developments in the aspect of education gave rise to a new paradigm in which participants acted as constructors in managing the information gained knowledge and educators as facilitators who guide students in learning activities with the aid of an electronic device. However, the use of electronic devices in the form of laptops/computers has not been well implemented to make students passive, and mathematical communication skills are not optimal. Students still consider the material of the Three Variable Linear Equation System to be quite difficult. So, we need innovative learning media in the form of e-modules. The purpose of this study was to develop the contents and find out the quality of e-modules in the material of the Mathematical Communication Based Three Variable Linear Equation System. This research is development research that adapts the ADDIE development model. The results of this study are in the form of an e-module on the material of the Three Variable Linear Equation System based on mathematical communication that can be operated on a laptop/computer offline. The product has been validated by media experts and material experts and gets results in the Good category. The product was also tested on 46 respondents and obtained results in the Good category. Thus, the e-module of the Three Variable Linear Equation System based on mathematical communication is appropriate for use in learning.
Keywords: e-module, Linear Equation System of three variables, mathematical communication.
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Liu, P., and Y. Zhang. "A computationally-efficient secondary organic aerosol module for three-dimensional air quality models." Atmospheric Chemistry and Physics 8, no. 14 (July 24, 2008): 3985–98. http://dx.doi.org/10.5194/acp-8-3985-2008.
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Abstract. Accurately simulating secondary organic aerosols (SOA) in three-dimensional (3-D) air quality models is challenging due to the complexity of the physics and chemistry involved and the high computational demand required. A computationally-efficient yet accurate SOA module is necessary in 3-D applications for long-term simulations and real-time air quality forecasting. A coupled gas and aerosol box model (i.e., 0-D CMAQ-MADRID 2) is used to optimize relevant processes in order to develop such a SOA module. Solving the partitioning equations for condensable volatile organic compounds (VOCs) and calculating their activity coefficients in the multicomponent mixtures are identified to be the most computationally-expensive processes. The two processes can be speeded up by relaxing the error tolerance levels and reducing the maximum number of iterations of the numerical solver for the partitioning equations for organic species; conditionally activating organic-inorganic interactions; and parameterizing the calculation of activity coefficients for organic mixtures in the hydrophilic module. The optimal speed-up method can reduce the total CPU cost by up to a factor of 31.4 from benchmark under the rural conditions with 2 ppb isoprene and by factors of 10–71 under various test conditions with 2–10 ppb isoprene and >40% relative humidity while maintaining ±15% deviation. These speed-up methods are applicable to other SOA modules that are based on partitioning theories.
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Nituca, Costica, Gabriel Chiriac, Dumitru Cuciureanu, Guoqiang Zhang, Dong Han, and Adrian Plesca. "Numerical Analysis of a Real Photovoltaic Module with Various Parameters." Modelling and Simulation in Engineering 2018 (2018): 1–12. http://dx.doi.org/10.1155/2018/7329014.
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This article presents a real photovoltaic module with modeling and simulations starting from the model of a photovoltaic (PV) cell. I-V, P-V, and P-I characteristics are simulated for different solar irradiation, temperatures, series resistances, and parallel resistances. For a real photovoltaic module (ALTIUS Module AFP-235W) there are estimated series and parallel resistances for which the energetical performances of the module have optimal values for a solar radiation of 1000 W/m2 and a temperature of the environment of 25°C. Temperature influence over the PV module performances is analyzed by using a thermal model of the ALTIUS Module AFP-235W using the finite element method. A temperature variation on the surface of the PV module is starting from a low value 40.15°C to a high value of 52.07°C. Current and power estimation are within the errors from 1.55% to about 4.3%. Experimental data are measured for the photovoltaic ALTIUS Module AFP-235W for an entire daylight.
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Pappas, Marios A., Eleftheria Demertzi, Yannis Papagerasimou, Lefteris Koukianakis, Nikitas Voukelatos, and Athanasios Drigas. "Cognitive-Based E-Learning Design for Older Adults." Social Sciences 8, no. 1 (January 4, 2019): 6. http://dx.doi.org/10.3390/socsci8010006.
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Aging is highly correlated with a decline in cognitive abilities. Information and communication technologies are nowadays increasingly used for knowledge acquisition, education, cognitive development, etc. Older adults should be prepared to adopt these technologies and take advantage of their capabilities. The purpose of this study was to analyze the cognitive profile of older adults in order to identify the ways that they learn, as well as to analyze older adults’ attitudes, to aid in the development of an e-learning platform adapted to their needs. The sample of the study consisted of 103 older adults, aged 55+, from Greece. According to their responses, older adults seemed to prefer e-learning modules that presented the educational content step-by-step and contained practice questions and examples. In addition, respondents had positive attitudes toward the existence of assessment tests for after the completion of each module. Finally, the utilization of explanatory videos and special graphics in the modules was imperative, according to older adults’ preferences.
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Ruwisch, Dietmar. "USER-ADAPTABLE HEARING AID COMPRISING AN INITIALIZATION MODULE." Journal of the Acoustical Society of America 134, no. 4 (2013): 3107. http://dx.doi.org/10.1121/1.4824246.
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Yu, Fang. "Application of Computer-Based Distance Education with Dynamic Webpages in Financial Management Courses." International Journal of Emerging Technologies in Learning (iJET) 16, no. 14 (July 28, 2021): 99. http://dx.doi.org/10.3991/ijet.v16i14.24047.
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Financial management is one of most important type of professional courses in the discipline of business management. The information-based teaching of the courses is a hot spot in the research of professional education. As a cutting-edge information technology, webpage technology provides a good information carrier that enables fast sharing, timely access, and opinion exchange of information. The application of information technology to distance education of financial management could promote the learning efficiency of the students. This paper mainly designs a computer-based distance education system with the aid of dynamic webpages. The system encompasses such modules like database, classroom module, and question and answer (Q&A) module. By introducing the operating mechanism of the system, this paper fully integrates the teaching resources and practices of financial management into the dynamic webpage-based system, providing students or trainees a convenient way of online learning. Through the integration of information technology in education, the proposed system promotes the reform of traditional education model, helps to improve teaching quality and learning efficiency, and enhances the students’ ability to analyze and implement financial management.
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Li, Hui Qi, Ding Liang, Yun Kun Ning, Qi Zhang, and Guo Ru Zhao. "Design and Realization of an Early Pre-Impact Fall Alarm System Based on MEMS Inertial Sensing Units." Applied Mechanics and Materials 461 (November 2013): 659–66. http://dx.doi.org/10.4028/www.scientific.net/amm.461.659.
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Falls are the second leading cause of unintentional injury deaths worldwide, so how to prevent falls has become a safety and security problem for elderly people. At present, because the sensing modules of most fall alarm devices generally only integrate the single 3-axis accelerometer, so the measured accuracy of sensing signals is limited. It results in that these devices can only achieve the alarm of post-fall detection but not the early pre-impact fall recognition in real fall applications. Therefore, this paper aimed to develop an early pre-impact fall alarm system based on high-precision inertial sensing units. A multi-modality sensing module embedded fall detection algorithm was developed for early pre-impact fall detection. The module included a 3-axis accelerometer, a 3-axis gyroscope and a 3-axis magnetometer, which could arouse the information of early pre-impact fall warning by a buzzer and a vibrator. Total 81 times fall experiments from 9 healthy subjects were conducted in simulated fall conditions. By combination of the early warning threshold algorithm, the result shows that the detection sensitivity can achieve 98.61% with a specificity of 98.61%, and the average pre-impact lead time is 300ms. In the future, GPS, GSM electronic modules and wearable protected airbag will be embedded in the system, which will enhance the real-time fall protection and timely immediate aid immensely for the elderly people.
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Bianchi Figueiredo, André, and Aníbal Coimbra Matos. "MViDO: A High Performance Monocular Vision-Based System for Docking A Hovering AUV." Applied Sciences 10, no. 9 (April 25, 2020): 2991. http://dx.doi.org/10.3390/app10092991.
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This paper presents a high performance (low computationally demanding) monocular vision-based system for a hovering Autonomous Underwater Vehicle (AUV) in the context of autonomous docking process-MViDO system: Monocular Vision-based Docking Operation aid. The MViDO consists of three sub-modules: a pose estimator, a tracker and a guidance sub-module. The system is based on a single camera and a three spherical color markers target that signal the docking station. The MViDO system allows the pose estimation of the three color markers even in situations of temporary occlusions, being also a system that rejects outliers and false detections. This paper also describes the design and implementation of the MViDO guidance module for the docking manoeuvres. We address the problem of driving the AUV to a docking station with the help of the visual markers detected by the on-board camera, and show that by adequately choosing the references for the linear degrees of freedom of the AUV, the AUV is conducted to the dock while keeping those markers in the field of view of the on-board camera. The main concepts behind the MViDO are provided and a complete characterization of the developed system is presented from the formal and experimental point of view. To test and evaluate the MViDO detector and pose an estimator module, we created a ground truth setup. To test and evaluate the tracker module we used the MARES AUV and the designed target in a four-meter tank. The performance of the proposed guidance law was tested on simulink/Matlab.
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Xie, Wenxiu, Ruoyao Ding, Jun Yan, and Yingying Qu. "A Mobile-Based Question-Answering and Early Warning System for Assisting Diabetes Management." Wireless Communications and Mobile Computing 2018 (June 6, 2018): 1–14. http://dx.doi.org/10.1155/2018/9163160.
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With increasing demand for preventive management of chronic diseases in real time by using the Internet, interest in developing a convenient device on health management and monitoring has intensified. Unlike other chronic diseases, diabetes particularly type 2 is a lifelong chronic disease and usually requires daily health management by patients themselves. This study is to develop a mobile-based diabetes question-answering (Q&A) and early warning system named Dia-AID, assisting diabetes patients and populations at high risk. The Dia-AID system consists of three modules: a large-scale multilanguage diabetes frequently asked question repository, a multimode fusion Q&A framework, and a health data management module. A list of services including risk assessment and health early warning is provided to users for health condition monitoring. Using the diabetes frequently asked question repository as data, experiments are conducted on answer ranking and answer selection aspects. Results show that two essential methods in the system outperform baseline methods on both aspects.
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Jeyan, J. V. Muruga Lal, Jency Lal, M. Senthil Kumar, and Arfaj Ahamed Anwar. "Flight manoeuvring and safe flight visualization with the aid of wide-ranging scrutiny and automation software." MATEC Web of Conferences 272 (2019): 01021. http://dx.doi.org/10.1051/matecconf/201927201021.
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This document guides to an efficient use of FDVCAS system. FDVCAS is a reconstruction, playback, interactive visualization tool, which collects, stores, processes, analyses and present the flight data in high fidelity graphical presentation in 2D and 3D format. It synchronizes and presents in both graphical and synthetic visual form to the extends of analysing the impact of the data on the system in 3D graphic animation. The existing process involves in capturing the data from different input sources and formats, analysing the features of the data monitoring is done manually in offline in a unsynchronized fashion, This is difficult, time consuming and requires highly skilled technical expertise as it is visualized in plain data form. The above standard procedures followed shall be integrated and automated with minimum intelligence to be built, in with the system. In order to analyse the flight data in a coherent way it is required to integrate both 2D and 3D form The proposed concept is the Development of a system with a single solution by providing data display, graphical charts and replay features with a sophisticated graphical user interface, which is super imposed on the outside window imagery. FDVCAS consists of Bypass data acquisition system, Outside Window Imagery (OWI) system with graphical analyser. Bypass data acquisition system receives data from aircraft recorder and transmits the data in engineering format to FDVCAS system. The OWI system has three main modules namely, 3D Visual module, GUI based Graphical analyser and Warning display module. The warnings and the graphical plots are super imposed on the 3D Visual.
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Pinto, Clara, and Carlos Eduardo Mady. "Exergetic Analysis of Hybrid Photovoltaic - Thermal Solar Collectors Coupled to Organic Rankine Cycles." Civil and Environmental Engineering Reports 28, no. 4 (December 1, 2018): 1–12. http://dx.doi.org/10.2478/ceer-2018-0046.
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Abstract In this work, the application of hybrid solar modules that combine photovoltaic panels and solar thermal collectors coupled with a low-temperature thermal cycle such as the Organic Rankine Cycle is discussed, their main purpose being an increase in the total electric power production per available area. This work will study the thermal and electrical power production efficiency of the hybrid system, the increase in the PV module electric conversion efficiency due to their cooling through heat transfer to the thermal cycle and the total exergetic efficiency of the system. A simplified simulation of the system in steady state conditions based on a thermal efficiency model will be performed with the aid of the EES (Engineering Equation Solver) software using climate data from Campinas, São Paulo, Brazil. The study shows that while the PV/T+ORC system does fulfill the purpose of increasing the electrical power generation both from the generator coupled to the thermal cycle and from the increase in the PV module efficiency due to its cooling. Thus, there is an increase the overall exergy efficiency of the system compared to uncoupled PV/T collectors.
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Karras, Georgios I., Georg Kustatscher, Heeran R. Buhecha, Mark D. Allen, Céline Pugieux, Fiona Sait, Mark Bycroft, and Andreas G. Ladurner. "The macro domain is an ADP-ribose binding module." EMBO Journal 24, no. 11 (May 19, 2005): 1911–20. http://dx.doi.org/10.1038/sj.emboj.7600664.
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Sauer, Joseph, and Christian Schmitt. "In-The-Ear Hearing Aid Having an Electronics Module." Journal of the Acoustical Society of America 129, no. 5 (2011): 3422. http://dx.doi.org/10.1121/1.3592854.
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van Beek, Johannes H. G. M. "Adenine nucleotide-creatine-phosphate module in myocardial metabolic system explains fast phase of dynamic regulation of oxidative phosphorylation." American Journal of Physiology-Cell Physiology 293, no. 3 (September 2007): C815—C829. http://dx.doi.org/10.1152/ajpcell.00355.2006.
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Computational models of a large metabolic system can be assembled from modules that represent a biological function emerging from interaction of a small subset of molecules. A “skeleton model” is tested here for a module that regulates the first phase of dynamic adaptation of oxidative phosphorylation (OxPhos) to demand in heart muscle cells. The model contains only diffusion, mitochondrial outer membrane (MOM) permeation, and two isoforms of creatine kinase (CK), in cytosol and mitochondrial intermembrane space (IMS), respectively. The communication with two neighboring modules occurs via stimulation of mitochondrial ATP production by ADP and Pi from the IMS and via time-varying cytosolic ATP hydrolysis during contraction. Assuming normal cytosolic diffusion and high MOM permeability for ADP, the response time of OxPhos ( tmito; generalized time constant) to steps in cardiac pacing rate is predicted to be 2.4 s. In contrast, with low MOM permeability, tmito is predicted to be 15 s. An optimized MOM permeability of 21 μm/s gives tmito = 3.7 s, in agreement with experiments on rabbit heart with blocked glycolytic ATP synthesis. The model correctly predicts a lower tmito if CK activity is reduced by 98%. Among others, the following predictions result from the model analysis: 1) CK activity buffers large ADP oscillations; 2) ATP production is pulsatile in beating heart, although it adapts slowly to demand with “time constant” ∼14 heartbeats; 3) if the muscle isoform of CK is overexpressed, OxPhos reacts slower to changing workload; and 4) if mitochondrial CK is overexpressed, OxPhos reacts faster.
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Hall, Matthew, and Jesper Kock. "ITE hearing aid and contact module for use in an ITE hearing aid." Journal of the Acoustical Society of America 121, no. 4 (2007): 1843. http://dx.doi.org/10.1121/1.2724034.
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Sheng, Zhong Qi, Yu Chang Liu, Yan Jin, and Yong Xian Liu. "Mass Customization–Oriented Module Combination Method." Advanced Materials Research 487 (March 2012): 395–400. http://dx.doi.org/10.4028/www.scientific.net/amr.487.395.
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For the modular design in manufacturing paradigm of mass customization (MC), module combination is a complex process. To the study on this problem, this paper put forward a module combination method based on module family model. Based on the module family model and tree-type storage structure, this method used a “most similar module" search algorithm to carry out the module search, and applied analytic hierarchy process(AHP) to construct the hierarchy model for the evaluation of module combination configuration program. This module combination method has some theoretical and practical ignificance.
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Malet, Hélène, Bruno Coutard, Saïd Jamal, Hélène Dutartre, Nicolas Papageorgiou, Maarit Neuvonen, Tero Ahola, et al. "The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket." Journal of Virology 83, no. 13 (April 22, 2009): 6534–45. http://dx.doi.org/10.1128/jvi.00189-09.
Full textAbstract:
ABSTRACT Macro domains (also called “X domains”) constitute a protein module family present in all kingdoms of life, including viruses of the Coronaviridae and Togaviridae families. Crystal structures of the macro domain from the Chikungunya virus (an “Old World” alphavirus) and the Venezuelan equine encephalitis virus (a “New World” alphavirus) were determined at resolutions of 1.65 and 2.30 Å, respectively. These domains are active as adenosine di-phosphoribose 1″-phosphate phosphatases. Both the Chikungunya and the Venezuelan equine encephalitis virus macro domains are ADP-ribose binding modules, as revealed by structural and functional analysis. A single aspartic acid conserved through all macro domains is responsible for the specific binding of the adenine base. Sequence-unspecific binding to long, negatively charged polymers such as poly(ADP-ribose), DNA, and RNA is observed and attributed to positively charged patches outside of the active site pocket, as judged by mutagenesis and binding studies. The crystal structure of the Chikungunya virus macro domain with an RNA trimer shows a binding mode utilizing the same adenine-binding pocket as ADP-ribose, but avoiding the ADP-ribose 1″-phosphate phosphatase active site. This leaves the AMP binding site as the sole common feature in all macro domains.
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Issa, Usama H., Yehia H. Miky, and Fam F. Abdel-Malak. "A DECISION SUPPORT MODEL FOR CIVIL ENGINEERING PROJECTS BASED ON MULTI-CRITERIA AND VARIOUS DATA." JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT 25, no. 2 (February 8, 2019): 100–113. http://dx.doi.org/10.3846/jcem.2019.7551.
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This paper develops a model, introduced in software, namely Multi-Criteria Decision-Making Model (MCDMM). The model helps decision makers selecting the most suitable alternative based on the customer requirements and preferences. Analytic Hierarchy Process (AHP) and Fuzzy Technique for Order of Preference by Similarity to Ideal Solution (Fuzzy TOPSIS) form a package that covers most available data types in construction projects. In MCDMM, AHP produces criteria relative weights according to their influence on the discussed problem, while Fuzzy TOPSIS is applied to rank the available alternatives. The model consists of two modules, first one uses AHP only to deal with precise, qualitative alongside quantitative data, while the other module combines AHP with Fuzzy TOPSIS due to the importance of linguistic variables to cover undocumented data. MCDMM is verified using two real case studies. The model is applied to a real case project for constructing solar power plants at Saudi Arabia. A decision required to select the most suitable surveying technique for producing Digital Terrain Model (DTM) among four alternatives (Total Station, Remote Sensing, Photogrammetry, and Global Positioning Systems). This issue is studied and key points are identified for prioritizing among them. Total Station is selected based on the model results.