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Dissertations / Theses on the topic 'Molecular and isotope chronostratigraphy'

Author: Grafiati

Published: 11 December 2022

Last updated: 31 July 2025

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1

Eiserbeck, Christiane. "Molecular and isotope chronostratigraphy of tertiary source rocks and crude oils." Thesis, Curtin University, 2011. http://hdl.handle.net/20.500.11937/1814.

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The exploration and production of petroleum from the subsurface is an important sector of industry to maintain the standards of our modern life. The availability of these natural resources has diminished in the past decades while the demand for their industrial products such as fuel or plastics is gradually increasing. Thus, there is a pressing need for effective and efficient techniques that improve future petroleum exploration strategies. The age of an oil is one of the most important parameters for oil‐source and oil‐oil correlations in order to understand petroleum systems. Currently, the

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2

Foster, Brian K. "Carbon Isotope controlled molecular switches /." May be available electronically:, 2009. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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3

Vohra, Jyotsna. "Stable isotope probing : a tool in molecular microbial ecology." Thesis, University of Warwick, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.443622.

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4

Cramer, Bradley D. "Application of Integrated High-Resolution Biochemostratigraphy to Paleozoic Chronostratigraphic Correlation: Recalibrating the Silurian System." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1245178129.

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5

Bell, Nicholle Georgina Anneke. "Molecular-scale characterisation of humic substances using isotope-filtered nD NMR spectroscopy." Thesis, University of Edinburgh, 2016. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.716584.

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Humic substances (HS), the complex mixture of organic molecules produced by microbial and abiotic degradation of plant and animals residues, are the major components of organic matter in soil and natural waters. As such, they are vital to the integrity of soil, play important roles in nutrient biogeochemical cycling and determine the mobility and fate of both nutrients and contaminants. How HS enact their varied roles, however, is largely unknown due to the lack of comprehension of their molecular make-up. What is known is that they contain aromatic (e.g. phenols, condensed aromatics) and alip

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6

Carr, R. H. "High sensitivity stable carbon isotope ratio mass spectrometry : instrument development application." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303835.

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7

Jansson, Magnus. "Quantum Chemical Calculations on ESR, Core Excitations, and Isotope Effects in Molecular Systems." Doctoral thesis, Uppsala University, Department of Quantum Chemistry, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4226.

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<p>In this thesis, quantum chemical calculations are undertaken mostly in order to interpret experimental results, but also to learn about computational techniques, their performance and their limitations. In paper I, the ionization-cleavage process of alkenes is investigated and two pathways are followed, one of initial cleavage and subsequent ionization and on the opposite, the other one of initial ionization and subsequent cleavage. The calculations reveal that ionization is best described by a vertical process, which is much faster than the relaxation of the molecule to its ionized structu

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8

Eveleigh, A. "The influence of fuel molecular structure on particulate emission investigated with isotope tracing." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1471621/.

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This thesis is concerned with the formation of particulate matter, a topic of scientific and practical importance due to the toxicity of particulate emissions from automotive and other combustion sources. At present, fuels are predominantly derived from fossil sources, but as production technology improves, biofuels and synthetic fuels are expected to emerge as scalable long-term sources of liquid fuels. Efforts are being made to ensure that this next-generation of fuels is cleaner burning than the last. In order to inform the production and processing of cleaner burning fuels, more needs to b

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9

Dickson, Luke. "Tracing Trophic Relationships of Insects in Cow Dung using Molecular and Stable Isotope Approaches." Thesis, University of Bristol, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520202.

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10

Volders, Filip Denis Maria. "Biomarker hydrocarbon molecular and deuterium isotope stratigraphic records from ombrotrophic mires for palaeoclimate reconstruction." Thesis, University of Bristol, 2003. http://hdl.handle.net/1983/78615790-8edd-4ec4-95d9-990c75e29988.

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11

Jameson, Elizabeth Frances Mary. "Development of solid phase-based PET isotope labelling methods." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/17973.

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Positron Emission Tomography (PET) has great value in research and clinical applications from oncology to neurodegenerative disorders. However, there is a barrier in translating biological knowledge into new PET applications due in part to the lack of efficient, widely applicable methods for labelling compounds with PET radioisotopes. Herein, a generic approach to radiolabelling is presented which is direct, broadly applicable and potentially adaptable to either of the two most commonly used PET radioisotopes, 11C and 18F. This approach employs the advantages of solid phase synthesis to achiev

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12

Favaro, Yvette Leeann. "Molecular characterization and carbon isotope ratio analysis of marine hydrocarbons in sediments from Trinity Bay, Newfoundland." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ34180.pdf.

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13

Ruhmann, Marc [Verfasser]. "Study of the isotope-dependence of molecular high-harmonic generation in D2 and H2 / Marc Ruhmann." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2019. http://d-nb.info/1176105221/34.

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14

Eley, Yvette. "Environmental and biochemical controls on the molecular distribution and stable isotope composition of leaf wax biomarkers." Thesis, University of East Anglia, 2014. https://ueaeprints.uea.ac.uk/52165/.

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Leaf wax n-alkyl lipids are increasingly used as proxies in palaeoclimate studies. Palaeovegetation assemblages are reconstructed from their molecular distribution patterns, while their δ13C and δ2H signals are thought to reflect plant-environment interactions and palaeohydrological shifts, respectively. Such applications depend, however, upon these compounds faithfully recording environmental conditions. To explore the influence of environmental, physical and biochemical controls on n-alkane composition, leaf waxes from seven UK saltmarsh plants were analysed over two growing seasons. Linked

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15

Sookdeo, Adam. "The Determination of 210Pb by Accelerator Mass Spectrometry." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32010.

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The aim of thesis was to establish a methodology for 210Pb measurements by Accelerator Mass Spectrometry (AMS). The potential application is to measure 210Pb in people who have been exposed to radon. This will better our understanding of radon toxicity, which is not possible now with current radiometric and mass spectrometry techniques. The determination of 210Pb by AMS was done in two major studies 1) Studying Pb chemistry in a Cs+ sputter source used in AMS and 2) Evaluating 204,205 & 208Pb spikes for the quantification of 210Pb by isotope dilution. Pb chemistry was investigated using an 834

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16

Dungait, Jennifer Anne June. "Molecular and compound-specific stable isotope investigation of the fate of dung carbon in a temperate grassland soil." Thesis, University of Bristol, 2005. http://hdl.handle.net/1983/fd1f5c75-ab9f-4e83-b3ec-0bf4225ab9dc.

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Concrete is regarded as a skeleton of aggregate particles of various sizes, almost in direct contact with each other. The cement matrix acts as a filler and adhesive enabling the structure to be able to carry tensile stresses. A 2D circular rigid discrete element formulation based on the Discrete Element Method has been adopted. Random assemblies of particles based on a given sieve analysis can be generated enabling the simulation of the concrete structure at the meso-level. Contact models that are able to transmit moments through the contact plane have been implemented, namely, a developed co

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17

Castleberry, Colette M. "Quantitative Identification of Non-coding RNAs by Isotope Labeling and LC-MS/MS." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1258474676.

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18

Chaput, Dale. "Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration." Scholar Commons, 2015. http://scholarcommons.usf.edu/etd/5921.

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Alzheimer’s disease (AD) is the most prevalent form of dementia affecting the elderly, and as the aging population increases the social and economic burden of AD grows substantially. Pathological hallmarks of AD include the accumulation of extracellular amyloid plaques and intracellular neurofibrillary tangles (NFTs), as well as significant neuron loss. Amyloid plaques consist of aggregated amyloid beta (Aβ) peptide, which is generated from the proteolytic processing of amyloid precursor protein (APP) in addition to several other peptides. While the processing of APP has been characterized, it

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19

Lynch, Anthony H. "Carbon isotopic dietary signatures of amino acids." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:1399009e-e06e-4f85-ba47-0557d5018cde.

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In an exploratory study, techniques were developed for isolating bulk plant proteins and measuring the <sup>13</sup>C isotopic compositions of their constituent amino acids by HPLC-IRMS. Samples of plants expected to be of potential palaeodietary significance in northwestern Europe were selected for investigation. Different tissues of plants, leaves and seeds, may be distinguished from each other by the relative <sup>13</sup>C isotopic compositions (‘isotopic signatures’) of the amino acids of their constituent proteins. For each tissue type, different plant types may be distinguished in the s

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20

Nielsen, Jens Munk. "Species interactions and energy transfer in aquatic food webs." Doctoral thesis, Stockholms universitet, Institutionen för ekologi, miljö och botanik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-123600.

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Food webs are structured by intricate nodes of species interactions which govern the flow of organic matter in natural systems. Despite being long recognized as a key component in ecology, estimation of food web functioning is still challenging due to the difficulty in accurately measuring species interactions within a food web. Novel tracing methods that estimate species diet uptake and trophic position are therefore needed for assessing food web dynamics. The focus of this thesis is the use of compound specific nitrogen and carbon stable isotopes and molecular techniques for assessing predat

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21

Wardle, Sophie L. "The impact of N-3 pufa ingestion on metabolic, molecular and epigenetic responses to a short-term high-fat diet." Thesis, University of Stirling, 2015. http://hdl.handle.net/1893/22368.

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Obesity is widely considered a primary risk factor for type 2 diabetes (T2D). However, less is known about the early adaptive responses to short-term periods of high-fat energy excess (HFEE). Previous reports detailing whole-body adaptation to fat and energy oversupply are equivocal, perhaps, in part, owing to use of different experimental protocols, varying durations of dietary manipulation and participant cohorts with individuals of varying characteristics. In addition to use of different dietary protocols between studies, alterations in functional end-point measures due to the type of dieta

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22

NAKAGAWA, Fumiko, Daisuke D. KOMATSU, Urumu TSUNOGAI, 書子中川, 大祐小松 та 潤. 角皆. "HIReTS法を用いた火山噴気の遠隔温度測定：薩摩硫黄島における検証". 日本火山学会, 2013. http://hdl.handle.net/2237/18700.

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23

Chiucchi, James Ernest Jr. "Genetic Diversity, Inbreeding and Diet Variation in an Endangered Rattlesnake, the Eastern Massasauga (Sistrurus c. catenatus)." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1316110529.

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24

Bignami, Giulia Paola Maria. "Exploiting isotopic enrichment for a solid-state NMR investigation of 'ADORable' zeolites and breathing metal-organic frameworks." Thesis, University of St Andrews, 2018. http://hdl.handle.net/10023/14202.

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This thesis combines synthetic studies for isotopic enrichment with solid-state characterisation techniques to investigate two classes of microporous materials: zeolites and metal-organic frameworks (MOFs). These materials have a wide range of successful applications, from industrial catalysis to medicine, resulting in the increasing need for both a complete understanding of their unique structural features and synthetic methods to target new frameworks. Nuclear magnetic resonance (NMR) spectroscopy, thanks to its sensitivity to the local, atomic-scale, environment and its element specificity,

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25

Ferlian, Olga [Verfasser], Stefan [Akademischer Betreuer] Scheu, Mark [Akademischer Betreuer] Maraun, and Ulrich [Akademischer Betreuer] Brose. "Soil animal food webs in temperate forests: effects of forest management on trophic structure as indicated by molecular gut content, stable isotope and fatty acid analyses / Olga Ferlian. Gutachter: Stefan Scheu ; Mark Maraun ; Ulrich Brose. Betreuer: Stefan Scheu." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/106544589X/34.

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26

Hautbergue, Thaïs. "Caractérisation chimique des métabolomes secondaires de Penicillium et Fusarium par marquage isotopique couplé à la spectrométrie de masse haute résolution." Thesis, Toulouse, INPT, 2017. http://www.theses.fr/2017INPT0110/document.

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Une méthode permettant de caractériser l’ensemble du métabolome secondaire de moisissures a été appliquée à la caractérisation des métabolomes de Penicillium nordicum, Penicillium verrucosum et Fusarium graminearum. Le substrat représentant l’unique source de carbone et d’azote des moisissures, chacun des champignons ont été mis en culture sur trois types de grains de blé: (i) grains naturels, (ii) grains marqués à 97% de 13C, et (iii) grains marqués à 53% 13C et 97% de 15N. Les extraits ont été analysés par HRMS. Les métabolites secondaires ont été spécifiquement détectés et leurs formules br

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27

Kamenova, Stefaniya. "Réseaux d'interactions, biodiversité et services éco-systémiques en milieu agricole : que nous apprennent les coléoptères carabiques ?" Thesis, Poitiers, 2013. http://www.theses.fr/2013POIT2319.

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Le contrôle des ravageurs est l'un des principaux services éco-systémiques rendus par la biodiversité à l'agriculture. Les communautés d'insectes auxiliaires, hébergées par les espaces agricoles présentent des niveaux de diversité, spécifique et fonctionnelle, élevés et leurs biologie et traits de vie sont bien décrits et étudiés. Ces communautés constituent donc un excellent modèle pour aborder des questions d'intérêt à la fois fondamental et appliqué sur les mécanismes à l'origine de la biodiversité et sur l'impact de la biodiversité sur l'approvisionnement en services éco-systémiques. Dans

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28

Réat, Valérie. "Étude de la dynamique fonctionnelle de la bactériorhodopsine par diffusion incohérente de neutrons et marquage isotopique." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10044.

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L'etude de la dynamique fonctionnelle de la bacteriorhodopsine (br) par diffusion elastique incoherente de neutrons entre dans le cadre de l'etude des relations dynamique-fonction. La br est une proteine membranaire situee dans une partie de la membrane plasmique (membrane pourpre - pm) d'une archaebacterie halophile, halobacterium salinarium. Elle fonctionne comme une pompe a protons activee par la lumiere. Une etude anterieure sur la dynamique globale de la br a revele une transition dynamique a 200 k entre un regime harmonique et un regime non-harmonique, transition fortement correlee a la

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29

Masakapalli, Shyam Kumar. "Network flux analysis of central metabolism in plants." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:ac8b3836-9ab7-4060-b50a-df8aaa0e4ba5.

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The aim of this thesis was to develop stable-isotope steady-state metabolic flux analysis (MFA) based on <sup>13</sup>C labeling to quantify intracellular fluxes of central carbon metabolism in plants. The experiments focus on the analysis of a heterotrophic cell suspension culture of Arabidopsis thaliana (L) Heynh. (ecotype Landsberg erecta). The first objective was to develop a robust methodology based on combining high quality steady-state stable labeling data, metabolic modeling and computational analysis. A comprehensive analysis of the factors that influence the outcome of MFA was undert

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30

"Carbon isotope controlled molecular switches." STANFORD UNIVERSITY, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=3351487.

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31

Kritee, Kritee. "Mass dependent stable isotope fractionation of mercury during its microbial transformations." 2008. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000051089.

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32

"Molecular and stable isotope analysis of Dehalococcoides bacteria in chlorinated ethene degrading communities." UNIVERSITY OF CALIFORNIA, BERKELEY, 2008. http://pqdtopen.proquest.com/#viewpdf?dispub=3306033.

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33

Ou, Yu-Meng, and 歐育孟. "Investigation of the unusual molecular isotope patterns of trimethylsilyl esters under GC-ESI/MS." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/64271569094300472984.

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碩士<br>國立臺灣大學<br>化學研究所<br>102<br>Gas Chromatography (GC) combined with Mass Spectrometry (MS) is widely used for the analysis of metabolomics. With the use of the GC-ESI/MS interface that was developed by our laboratory to analyze the TMS (Trimethylsilyl) derivatives of organic acids, we have observed unusual high abundance of [M+3]+ ions. The abundance of [M+3]+ ions were as high as a third of the protonated molecule [M+H]+ ions. Based on the speculation of reduction of the C=O double bond (from R-CO2-Si(CH3)3 to R-H(COH)-O-Si(CH3)3), we proposed a possible structure of the unusual [M+3]+ ions

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34

Evans, Curtis. "Molecular composition and isotope mapping of natural gas in the British Columbia Natural Gas Atlas." Thesis, 2019. https://dspace.library.uvic.ca//handle/1828/10569.

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This thesis provides a geochemical interpretation of natural gas resources in north eastern British Columbia (NEBC), Canada. The work is part of the three-year project, British Columbia Natural Gas Atlas (BC-NGA) to collect samples and compile data on molecular (C1 to C5) and stable isotope ratio (δ13C and δ2H) compositions of natural gases in NEBC. The primary objective of the BC-NGA project is to produce a comprehensive, public, web database with maps of the gas geochemical data from a variety of gas tests including mudgas collected during drilling, downhole flow tests, production gas, and

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35

Favaro-Park, Yvette Leeann. "Molecular characterization and carbon isotope ratio analysis of marine hydrocarbons in sediments from Trinity Bay, Newfoundland /." 1998.

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36

Ostrom, Margaret Harrigan. "Geochemical characterization of high molecular weight organic material isolated from late Cretaceous fossils /." 1990. http://collections.mun.ca/u?/theses,88690.

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37

Hong, Nan-Sook. "Molecular basis of the evolution of new protein functions: Kemp elimination and phosphoryl transfer reactions." Phd thesis, 2016. http://hdl.handle.net/1885/116927.

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This is a series of investigations into the molecular basis of the evolution of new protein functions. The broad objective of this work was to determine exactly how a series of single amino acid mutations, typical of an evolutionary trajectory, can result in dramatic changes in catalytic activity, specificity and protein solubility. Various strategies were employed to achieve this aim, including analysis of existing literature concerning the various models and theories relating to molecular evolution, protein crystallography, extensive enzyme kinetics an

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38

Bourbonnais, Annie. "Fixed nitrogen loss in two variably anoxic marine environments: the subsurface biosphere of hydrothermal vents (Juan de Fuca Ridge, northeast Pacific) and Saanich Inlet, a British Columbia fjord." Thesis, 2012. http://hdl.handle.net/1828/4323.

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We investigated oceanic dissolved inorganic nitrogen (N) dynamics, focussing on processes removing bio-available N and ultimately affecting primary productivity, in sulfidic hydrothermal vent fluids discharging from the subsurface on the Juan de Fuca Ridge (northeast Pacific Ocean) and in anoxic bottom waters of Saanich Inlet, a British Columbia fjord, using a combination of geochemical and molecular microbial ecology techniques. During episodes of mixing with oxygenated sea-water, both systems can switch from anoxic to oxic conditions. Strong inter-site variations in the concentrations and

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39

Hall, Philip Anthony. "Elemental, isotopic and molecular signatures of Early Cambrian marine sediments and a phantom petroleum system in South Australia." Thesis, 2012. http://hdl.handle.net/2440/81757.

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The aim of the research study is to apply mass spectrometric geochemical techniques to the investigation of palaeoenvironmental, chemostratigraphic and provenance questions from several South Australian Phanerozoic basins. Results of a multi-pronged palaeoenvironmental investigation of Early Cambrian marine sediments, employing trace and REE abundances, TOC and stable isotopes (C, S) are reported from three formations in the Stansbury Basins; Heatherdale Shale, Emu Bay Shale and Talisker Formation. The multiproxy approach in conjunction with sedimentological information provides a powerful too

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40

Ferlian, Olga. "Soil animal food webs in temperate forests: effects of forest management on trophic structure as indicated by molecular gut content, stable isotope and fatty acid analyses." Doctoral thesis, 2014. http://hdl.handle.net/11858/00-1735-0000-0015-A381-9.

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Liu, X., L. Hu, G. Ge, et al. "Quantitative analysis of cytochrome P450 isoforms in human liver microsomes by the combination of proteomics and chemical probe-based assay." 2014. http://hdl.handle.net/10454/10502.

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No<br>Cytochrome P450 (CYP) is one of the most important drug-metabolizing enzyme families, which participates in the biotransformation of many endogenous and exogenous compounds. Quantitative analysis of CYP expression levels is important when studying the efficacy of new drug molecules and assessing drug-drug interactions in drug development. At present, chemical probe-based assay is the most widely used approach for the evaluation of CYP activity although there are cross-reactions between the isoforms with high sequence homologies. Therefore, quantification of each isozyme is highly desired

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Seibert, C., B. R. Davidson, B. J. Fuller, Laurence H. Patterson, W. J. Griffiths, and Y. Wang. "Multiple-approaches to the identification and quantification of cytochromes P450 in human liver tissue by mass spectrometry." 2009. http://hdl.handle.net/10454/6179.

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Here we report the identification and approximate quantification of cytochrome P450 (CYP) proteins in human liver microsomes as determined by nano-LC-MS/MS with application of the exponentially modified protein abundance index (emPAI) algorithm during database searching. Protocols based on 1D-gel protein separation and 2D-LC peptide separation gave comparable results. In total, 18 CYP isoforms were unambiguously identified based on unique peptide matches. Further, we have determined the absolute quantity of two CYP enzymes (2E1 and 1A2) in human liver microsomes using stable-isotope dilution m

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