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Dissertations / Theses on the topic 'Molecular Communication'

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1

Cecchi, Dario. "Molecular communication between artificial cells." Doctoral thesis, Università degli studi di Trento, 2017. https://hdl.handle.net/11572/368520.

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Genetic engineering has been widely used to reprogram cells for a variety of purposes, suggesting a wide range of possible applications in industrial and academic research. Although the techniques available are very well established, the mechanisms of cellular life are not completely understood. Therefore, despite offering a versatile tool, engineered cells are prone to possible unexpected behaviors. Investigations of more controllable systems are partially focused on the creation of cellular mimics assembled from discrete components with defined properties. The controlled assembly of molecule
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Cecchi, Dario. "Molecular communication between artificial cells." Doctoral thesis, University of Trento, 2017. http://eprints-phd.biblio.unitn.it/1924/2/Dario_Cecchi_PhD_Thesis_final_online.pdf.

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Genetic engineering has been widely used to reprogram cells for a variety of purposes, suggesting a wide range of possible applications in industrial and academic research. Although the techniques available are very well established, the mechanisms of cellular life are not completely understood. Therefore, despite offering a versatile tool, engineered cells are prone to possible unexpected behaviors. Investigations of more controllable systems are partially focused on the creation of cellular mimics assembled from discrete components with defined properties. The controlled assembly of molecul
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3

Mahfuz, Mohammad Upal. "Fundamentals of Concentration-encoded Molecular Communication." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31767.

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Molecular communication (MC) is a new bio-inspired communication paradigm towards realizing the communication and networking at the nanoscale to microscale dimensions among a vast number of engineered natural and/or artificial nanomachines communicating with each other to form a nanonetwork. In this thesis, we investigate a concentration-encoded molecular communication (CEMC) system where the transmitting nanomachine (TN) and the receiving nanomachine (RN) communicate with a single type of information molecules by modulating the transmission rate of information molecules at the TN. The informa
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4

Qiu, Song. "Molecular communication systems : design, modelling and experimentation." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/95162/.

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Molecular Communications (MC) is an increasingly attractive technique to enable the communication and networking of devices in environments where traditional communication techniques may not be suitable. MC has been used to convey information in both human society and in animal populations and been studied on both the microscale and the macroscale. On the basis of these studies, this thesis focuses on characterising MC channel models under different environments and examining the impact these models have on the communication performance. The thesis begins by reviewing the latest developments i
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Damrath, Martin [Verfasser]. "Channel Coding in Molecular Communication / Martin Damrath." Düren : Shaker, 2020. http://d-nb.info/1225653967/34.

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6

Bicen, Ahmet Ozan. "Fundamentals of molecular communication over microfluidic channels." Diss., Georgia Institute of Technology, 2016. http://hdl.handle.net/1853/55009.

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The interconnection of molecular machines with different functionalities to form molecular communication systems can increase the number of design possibilities and overcome the limited reliability of the individual molecular machines. Artificial information exchange using molecular signals would also expand the capabilities of single engineered cell populations by providing them a way to cooperate across heterogeneous cell populations for the applications of synthetic biology and lab-on-a-chip systems. The realization of molecular communication systems necessitates analysis and design of the
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7

Lu, Yi. "Error correction codes for molecular communication systems." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/88085/.

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Molecular communications (MC) is a bio-inspired paradigm that aims to utilise molecules to exchange information among nano-machines. Given the tiny devices used in a MC system and the feasibility of MC in biological environments, MC can be applied to many applications ranging from the healthcare to manufacturing fields. In order to better realize these applications in the future, this Ph.D. research is dedicated to the investigation of a more functional, precise and reliable Diffusion-based Molecular Communications (DBMC) system. To achieve this goal, the contributions of this thesis are as fo
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8

Pierobon, Massimiliano. "Fundamentals of diffusion-based molecular communication in nanonetworks." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50234.

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Molecular communication (MC) is a promising bio-inspired paradigm for the exchange of information among nanotechnology-enabled devices. These devices, called nanomachines, are expected to have the ability to sense, compute and actuate, and interconnect into networks, called nanonetworks, to overcome their individual limitations and benefit from collaborative efforts. MC realizes the exchange of information through the transmission, propagation, and reception of molecules, and it is proposed as a feasible solution for nanonetworks. This idea is motivated by the observation of nature, where MC i
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Assaf, Simon Sassine. "Synthetic biology guidelines for diffusion based molecular communication." Doctoral thesis, Universitat Politècnica de Catalunya, 2019. http://hdl.handle.net/10803/667123.

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Nanotechnology is widely seen as having huge potential to bring benefits to many areas of research and application. Nowadays, research studies are focusing on realizing nano-machines on the order of nanometers in size. A nano-machine is capable of performing simple tasks such as computing, data storing, sensing, and actuation. The capability for such nano-machine to communicate with each other would considerably expand their potential. Thereby, in order to fulfill more complex tasks nano-networks are needed. Indeed, nanonetworks are the connection and cooperation of millions of nano-machines.
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10

Noel, Adam. "Modeling and analysis of diffusive molecular communication systems." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54906.

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Diffusive molecular communication (MC) is a promising strategy for the transfer of information in synthetic networks at the nanoscale. If such devices could communicate, then it would expand their cumulative capacity and potentially enable applications such as cooperative diagnostics in medicine, bottom-up fabrication in manufacturing, and sensitive environmental monitoring. Diffusion-based MC relies on the random motion of information molecules due to collisions with other molecules. This dissertation presents a novel system model for three-dimensional diffusive MC where molecules can also be
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11

Sun, Yue. "Channel modelling of blood capillary-based molecular communication." Thesis, University of Essex, 2018. http://repository.essex.ac.uk/22451/.

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Molecular communication (MC) is a new and promising interdisciplinary bio-inspired communication paradigm, which uses molecules as information carriers. Differing from traditional communication, MC is proposed as a feasible solution for nanoscale communication with the help of biological scenarios to overcome the communication limitations. Meanwhile, it is inspired by intracellular and intercellular communication, which involves exchange of information through the transmission, propagation, and reception of molecules. Blood capillaries, extensively distributed in the human body and mutually co
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12

Gul, Ertan. "Nanosim: A Simulation Framework For Nanoscale Molecular Communication Networks." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/3/12611882/index.pdf.

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A number of nanomachines that cooperatively communicate and share information in order to achieve specific tasks is envisioned as a nanonetwork. Due to size and capabilities of nanomachines, the traditional communication paradigms cannot be used for nanonetworks in which network nodes may be composed of just several atoms or molecules and scale on the orders of few nanometers. Instead, the molecular communication is a promising solution approach for nanoscale communication paradigm. However, molecular communication must be thoroughly investigated to realize the nanoscale communication and nano
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13

Dimick, Emily. "A Comparative Study on Pheromone Communication between Schizophyllum species." Thesis, Southern Illinois University at Edwardsville, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1590875.

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<p> Many fungal species are studied to understand pheromone and receptor interaction associated with mating behavior. An established genetic model for mating in higher fungi is heterothallic <i>Schizophyllum commune </i>. This fungus uses its pheromones to communicate compatibility among mates, typically leading to the production of haploid meiotic basidiospores. <i> S. commune</i> has thousands of mating types, as part of its tetrapolar mating system in which mating is determined by two unlinked complex genetic loci, one of which codes for both mating pheromones and receptors (<i> matB</i>).
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14

Singhal, Amit. "Performance of amplitude modulation schemes for molecular communication over a fluid medium." Thesis, IIT Delhi, 2016. http://localhost:8080/xmlui/handle/12345678/7011.

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15

Wang, Xiayang. "The design and performance analysis of diffusive molecular communication systems." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/80019/.

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Molecular Communications (MC) is an increasingly attractive technique to enable the networking of nano-machines by utilising molecules as the information carrier. The molecular diffusion can be described by either the movement of individual molecules or the molecular concentration. Accordingly, two kinds of diffusive MC systems have been modelled in previous literature. On the basis of these studies, the aim of this Ph.D. is to refine these two models, to implement functional transmission techniques and technologies, and to investigate the corresponding system performance. To fulfil this targe
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Cox, Helen. "Translating molecular diagnostics : Innovation, communication and the dynamics of clinical implementation." Thesis, University of York, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495866.

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17

Llopis, Lorente Antoni. "Enzyme-functionalized hybrid mesoporous nanodevices for sensing, controlled release and molecular communication." Doctoral thesis, Universitat Politècnica de València, 2019. http://hdl.handle.net/10251/117612.

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[ES] La presente tesis doctoral titulada "Nanodispositivos mesoporosos híbridos funcionalizados con enzimas para detección, liberación controlada y comunicación molecular" se centra en el diseño, preparación, caracterización y evaluación de distintos nanodispositivos híbridos orgánico-inorgánicos utilizando como soporte nanopartículas tipo Janus de oro y sílice mesoporosa, que se equipan con enzimas, especies fluorescentes y puertas moleculares. Como conclusión general, los estudios realizados muestran que la incorporación de enzimas sobre nanopartículas permite introducir funciones de recono
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18

Saeed, Musaab. "Performance of MIMO Molecular Communications in Diffusion-Based Channels." University of Akron / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=akron1499865087940384.

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19

Aubailly, Simon. "From coarse-grained to atomistic molecular modeling : how structure and dynamics shape intra-molecular communication and functional sites in proteins." Thesis, Orléans, 2017. http://www.theses.fr/2017ORLE2002/document.

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Dans cette thèse, nous nous sommes intéressés à la relation subtile qui existe entre lesstructures complexes des protéines et leurs fonctions encore plus raffinées que ces dernièreseffectuent. Basés sur deux descriptions différentes des protéines, à l’échelle de acide-aminé età l’echelle atomique, un de nos objectifs était de connecter des indicateurs structuraux calculésà partir de la topologie des protéines à des sites fonctionnels tels que les sites catalyiquesdans les enzymes. Un autre pan de la recherche de cette thèse était d’utiliser nos outils baséssur la structure et de mettre au poin
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20

Ayroles, Sarah DeLeigh. "Molecular and Physiological Mechanisms Underlying Chemical Communication in the Honey Bee, Apis mellifera." NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-08112009-235911/.

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From prokaryotes to vertebrates, the use of chemical signals is widespread. However, the underlying mechanisms that have led to the diversification of chemical communication are poorly understood. Here, I focus on the pheromonal communication system of the honey bee, Apis mellifera, and describe some of the molecular and physiological mechanisms that underlie pheromone production and response in this species. The mandibular glands of queen honey bees produce a pheromone (QMP) which modulates many aspects of worker behavior and physiology, and is critical for colony social organization. Chapter
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21

Higgenbottom, Morris Scott. "Liquid crystal modulation of retroreflection : a low-power communication/location technology." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/16695.

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22

Nudel, Ron. "Molecular genetics of language impairment." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:70249129-ef2e-4508-b8f6-50d6eae8e78b.

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Developmental language impairments are neurodevelopmental disorders in which the acquisition of language, a task which children typically perform with ease, is hindered or fraught with difficulty. This work focuses on specific language impairment (SLI), a common and highly heritable language impairment in which language development is abnormal while other developmental domains are normal. Additionally, a case-study of a child with a broader linguistic and behavioural phenotype is also presented. The work described in this thesis includes both genetic and functional investigations which were ai
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23

Godard, Kimberley-Ann. "A molecular approach to study the monoterpene-induced response in Arabidopsis thaliana." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/271.

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A wound- and insect-inducible expression system for transgenic plants was developed. Specifically, I demonstrate wound- and insect-inducible, localized gene expression driven by the potato proteinase inhibitor II (pinII)-promoter in transformed Arabidopsis, tobacco and white spruce. As reporter and target genes driven by the pinII-promoter, I used the GUS gene and a terpenoid synthase gene, respectively. In addition, I found that the pinII-promoter drives trichome-specific, systemically-induced gene expression in tobacco and Arabidopsis. Finally, I demonstrate that the pinII–promoter, when tra
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24

Zhang, Yuan. "STM Investigation of Electric Polar Molecular Self-Assembly and Artificial Electric Polar Molecular Rotors." Ohio University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1416927903.

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25

Costescu, Ion Bogdan [Verfasser], and Robert B. [Akademischer Betreuer] Russell. "Time-Resolved Force Distribution Analysis for Molecular Communication / Ion Bogdan Costescu ; Betreuer: Robert B. Russell." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177382504/34.

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26

RAFFAELE, STEFANO. "MICROGLIA-TO-OLIGODENDROCYTE PRECURSOR CELLS COMMUNICATION AFTER STROKE: MOLECULAR MECHANISMS AND IMPLICATIONS FOR MYELIN REPAIR." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/883201.

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L'ischemia cerebrale è un disturbo neurologico di origine cardiovascolare che rappresenta una delle principali cause di morte e disabilità permanente nel mondo, per il quale mancano terapie rigenerative efficaci. La degenerazione degli oligodendrociti e il conseguente deterioramento della guaina mielinica sono considerati tra i principali fattori che contribuiscono ai deficit neurologici associati a tale patologia. Pertanto, promuovere la riparazione della guaina mielinica attraverso la generazione di nuovi oligodendrociti mielinizzanti potrebbe rappresentare un approccio terapeutico prometten
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Krishnaswamy, Bhuvana. "When bacteria talk : time elapse communication for super-slow networks." Thesis, Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/50312.

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In this work we consider nano-scale communication using bacterial popula- tions as transceivers. We demonstrate using a microfluidic test-bed and a population of genetically engineered Escherichia coli bacteria serving as the communication re- ceiver that a simple modulation like on-off keying (OOK) is indeed achievable, but suffers from very poor data-rates. We explore an alternative communication strategy called time elapse communication (TEC) that uses the time period between signals to encode information. We identify the severe limitations of TEC under practical non-zero error conditions i
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Badruzsaufari. "Molecular analysis of cross communication between signal transduction pathways during pathogen resistance response in Arabidopsis thaliana /." [St. Lucia, Qld.], 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe18619.pdf.

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Jamali, Vahid [Verfasser], Robert [Akademischer Betreuer] Schober, and Antonia M. [Gutachter] Tulino. "Design and Analysis of Molecular Communication Systems / Vahid Jamali ; Gutachter: Antonia M. Tulino ; Betreuer: Robert Schober." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2019. http://d-nb.info/1181428688/34.

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Damrath, Martin [Verfasser], Peter [Akademischer Betreuer] Höher, Robert [Gutachter] Schober, and H. Birkan [Gutachter] Yilmaz. "Channel Coding in Molecular Communication / Martin Damrath ; Gutachter: Robert Schober, H. Birkan Yilmaz ; Betreuer: Peter Höher." Kiel : Universitätsbibliothek Kiel, 2020. http://d-nb.info/1221599755/34.

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Figueiredo, Melina Fernandes. "Development and application of novel molecular tools to study astrocyte-to-neurone communication in the brain." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.687420.

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My PhD project focused on the development and validation of new molecular tools expressing the variants of channelrhodopsin-2 (ChR2), ChR2(HI34R) and Ca2+ translocating channel rhodopsin (CatCh), and a potent ectonucleotidase, transmembrane prostatic acid phosphatase (TMPAP). Optogenetic stimulation of ChR2(H134R) and CatCh evoked astrocytic intracellular calcium ([Ca2+]i) elevations, which were mediated by Ca2+ release from the endoplasmic reticulum (ER), and autocrine action of ATP. [Ca2+]i transients in ChR2(H 134R)-expressing astrocytes were also partially dependent on external Ca2+, and l
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Guney, Aydin. "Mobile Ad Hoc Molecular Nanonetworks." Master's thesis, METU, 2010. http://etd.lib.metu.edu.tr/upload/12612092/index.pdf.

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Recent developments in nanotechnology have enabled the fabrication of nanomachines with very limited sensing, computation, communication, and action capabilities. The network of communicating nanomachines is envisaged as nanonetworks that are designed to accomplish complex tasks such as drug delivery and health monitoring. For the realization of future nanonetworks, it is essential to develop novel and efficient communication and networking paradigms. In this thesis, the first step towards designing a mobile ad hoc molecular nanonetwork (MAMNET) with electrochemical communication is taken. MAM
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Chen, Shanze [Verfasser], and Silke [Akademischer Betreuer] Meiners. "Molecular mechanism of alveolar macrophage polarization and cell communication with alveolar epithelial cell / Shanze Chen. Betreuer: Silke Meiners." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1080479074/34.

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Ascano, Janice Mae. "JAGGED1 Mediates Bi-Directional Cell-Cell Communication: Implications in Carcinogenesis and Thymic Development." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1109018032.

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35

MERCORIO, ROBERTA. "AIR POLLUTION EXPOSURE AND HEALTH EFFECTS: CELL-SHED MICROVESICLES AS CARRIERS FOR INTERCELLULAR COMMUNICATION." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/557918.

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Air pollution exposure is a major problem worldwide and is associated with several diseases, but the molecular mechanisms underlying these associations still remain unknown. Obesity may increase susceptibility to the adverse effects of PM exposure, exacerbating the effects of PM on human health. Extracellular vesicles (EVs), which travel in body fluids and transfer molecular messages among tissues, might play an important role in connecting external exposures to health effects. We examined the effects of PM exposure in a population of 50 healthy subjects stratified for BMI on molecular alter
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de, Luis Fernández Beatriz. "Development of enzyme-functionalized hybrid mesoporous nanodevices for advanced chemical communication." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/171506.

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Tesis por compendio<br>[ES] La presente tesis doctoral se centra en el diseño, síntesis y caracterización de varios nanodispositivos híbridos orgánico-inorgánicos, utilizando como soporte nanopartículas de sílice mesoporosa equipadas con enzimas y puertas moleculares, los cuales muestran capacidades comunicativas además de la evaluación de diferentes estrategias de comunicación. El primer capítulo incluye un resumen de diferentes conceptos sobre los que se fundamentan los estudios realizados tales como nanotecnología, materiales de sílice mesoporosa, materiales con puertas moleculares que
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Jonusauskaite, Laura. "Calixarènes et spiropyranes : conception de nouveaux systèmes supramoléculaires photocontrôlés." Thesis, Bordeaux 1, 2011. http://www.theses.fr/2011BOR14393/document.

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Le projet de recherche de cette thèse a pour ambition la conception de nouveaux récepteurs moléculaires artificiels exploitant les propriétés complexantes des calixarènes, des éther-couronnes et des complexes insaturés de lanthanides liées aux propriétés photophysiques et photochimiques de photochromes spiropyraniques. L’alliance supramoléculaire ainsi formée doit permettre d’exploiter les processus de photoéjection et ensuite de détection par un site distant, c’est-à-dire d’établir une communication à l’échelle moléculaire grâce à la lumière. Un récepteur moléculaire employant le calix[4]arèn
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Ho, Brian Thomas. "Characterization of the Antibacterial Activity of the Type VI Secretion System." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11241.

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This dissertation summarizes advances made toward understanding of the composition, structure, mechanism, and regulation of the bacterial type VI secretion system (T6SS). The T6SS is a widely conserved bacterial nanomachine used by Gram-negative bacteria to deliver toxic effector proteins into the extracellular environment or into adjacent target cells. Systematic deletion of open reading frames present in the Vibrio cholerae T6SS gene cluster revealed the genes essential for T6SS activity and provided key insights into understanding the mechanism by which this organelle is assembled and its c
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Thuillier, Jordhan. "Déterminants structuraux de la régulation de la compétence par le système de communication ComRS chez les streptocoques." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS504/document.

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Les bactéries utilisent la communication intercellulaire pour se coordonner afin de réguler des processus bactériens majeurs comme la virulence, la sporulation, la compétence ou la formation de biofilms en fonction de la densité cellulaire. Ce processus repose sur la sécrétion de petites molécules signal appelées phéromones. Chez les bactéries à gram positif, ces phéromones sont de petits peptides qui peuvent être, soit reconnus au niveau de la membrane externe par des systèmes à deux composants dits systèmes indirects, soit être re-internalisés afin de se fixer directement sur un régulateur t
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Tron, Arnaud. "Molécules entrelacées : conception, photocapture et commutation photoinduite." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0277/document.

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L’implémentation d’un agent structurant impliquant un macrocycle à 31membres et intégrant un récepteur de type Hamilton / bis(2,6-diamidopyridine) a permis deconcevoir des [2]rotaxanes via une réaction click catalysée par du cuivre(I), soit à partir d’unpseudorotaxane en présence d’un barbiturique fonctionnalisé, soit par une méthode de« gabarit actif ». Ces structures supramoléculaires ont été rendues photochimiquement activesen exploitant des analogues de récepteurs Hamilton incorporant des groupementsphotodimérisables de type 9-anthracène. La photodimérisation et la retrodimérisation de ces
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Jogenfors, Jonathan. "Breaking the Unbreakable : Exploiting Loopholes in Bell’s Theorem to Hack Quantum Cryptography." Doctoral thesis, Linköpings universitet, Informationskodning, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140912.

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In this thesis we study device-independent quantum key distribution based on energy-time entanglement. This is a method for cryptography that promises not only perfect secrecy, but also to be a practical method for quantum key distribution thanks to the reduced complexity when compared to other quantum key distribution protocols. However, there still exist a number of loopholes that must be understood and eliminated in order to rule out eavesdroppers. We study several relevant loopholes and show how they can be used to break the security of energy-time entangled systems. Attack strategies are
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Simard, Jean. "Collaboration haptique étroitement couplée pour la manipulation moléculaire interactive." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00688036.

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Le docking moléculaire est une tâche complexe, difficile à appréhender pour une personne seule. C'est pourquoi, nous nous proposons d'étudier la distribution cognitive des charges de travail à travers la collaboration. Une plate-forme distribuée de déformation moléculaire interactive a été mise en place afin d'étudier les avantages mais aussi les limites et les contraintes du travail collaboratif étroitement couplé. Cette première étude, basée sur trois expérimentations, a permis de valider l'intérêt d'une approche collaborative pour des tâches complexes à fort couplage.
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Fernández, Sanz Celia. "Defective sarcoplasmic reticulum-mitochondria communication in aged heart and its effect on ischemia and reperfusion injury." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/323906.

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Las alteraciones mitocondriales están vinculadas a la mayor vulnerabilidad de padecer enfermedades durante el envejecimiento. La edad avanzada es un factor determinante de la incidencia y gravedad de la cardiopatía isquémica. Estudios preclínicos sugieren la existencia de un daño celular intrínseco, por mecanismos no del todo establecidos, que contribuye a un incremento de la susceptibilidad del miocardio senescente al daño isquémico. Esta tesis investiga el papel de la comunicación mitocondria-retículo sarcoplásmico (RS) en el deterioro funcional de los cardiomiocitos durante el envejecimien
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Kindgren, Peter. "The chloroplast talks : Insights into the language of the chloroplast in Arabidopsis." Doctoral thesis, Umeå universitet, Institutionen för fysiologisk botanik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36166.

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The chloroplast originates from an endosymbiotic event 1.5 billion years ago, when a free living photosynthetic bacteria was engulfed by a eukaryotic host. The chloroplastic genome has through evolution lost many genes to the nuclear genome of the host. To coordinate the gene expression between the two genomes, plants have evolved two types of communication, nucleus-to-plastid (anterograde) and plastid-to-nucleus (retrograde) signalling. This thesis will focus on retrograde communication with emphasis on redox and tetrapyrrole mediated signalling. In this thesis, we establish the tetrapyrrole
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45

Karami, Yasaman. "Joint analysis of dynamically correlated networks and coevolved residue clusters : large-scale analysis and methods for predicting the effects of genetic disease associated mutations." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066375/document.

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Nous avons présenté COMMA, une méthode pour décrire et comparer les architectures dynamiques de différentes protéines. Il extrait propriétés dynamiques de ensembles conformationnels pour identifier les voies de communication, des chaînes de résidus liés par des interactions stables qui se déplacent ensemble, et cliques indépendants, des groupes de résidus qui fluctuent de manière concertée. Il fournit une description de l'infostery d'un complexe de protéines qui va au-delà des mesures au-delà de classiques de la façon dont une protéine se déplace ou change de forme. Nous avons montré l'efficac
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Tiger, Carl-Fredrik. "Cellular Interactions with Extracellular Matrix During Development and in Muscle Disease." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2002. http://publications.uu.se/theses/91-554-5328-7/.

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47

Karami, Yasaman. "Joint analysis of dynamically correlated networks and coevolved residue clusters : large-scale analysis and methods for predicting the effects of genetic disease associated mutations." Electronic Thesis or Diss., Paris 6, 2016. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2016PA066375.pdf.

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Nous avons présenté COMMA, une méthode pour décrire et comparer les architectures dynamiques de différentes protéines. Il extrait propriétés dynamiques de ensembles conformationnels pour identifier les voies de communication, des chaînes de résidus liés par des interactions stables qui se déplacent ensemble, et cliques indépendants, des groupes de résidus qui fluctuent de manière concertée. Il fournit une description de l'infostery d'un complexe de protéines qui va au-delà des mesures au-delà de classiques de la façon dont une protéine se déplace ou change de forme. Nous avons montré l'efficac
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48

Petit, Jules. "Membrane Tethering in Plant Intercellular Communication : Structure-Function of Multiple C2 domains and Transmembrane Region Proteins (MCTP) at Plasmodesmata ER-PM Membrane Contact Site." Thesis, Bordeaux, 2022. https://tel.archives-ouvertes.fr/tel-03789611.

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La multicellularité chez les plantes repose sur une communication intercellulaire qui permette le transfert d'informations à travers l'entièreté de l'organisme. Chez les plantes terrestres, la route principale de ces “conversations cellulaires” est assurée par les plasmodesmes (PD), des canaux nanoscopiques qui traversent la paroi pecto-cellulosique. En effet, ces pores sont impliqués dans la circulation d'une très grande variété de molécules, comme des facteurs de transcription, de l'ARN, des hormones et des métabolites et ceci à tous les stades de la vie végétale, permettant réponses et adap
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Qian, Xuewen. "Advanced Detection and Synchronization Schemes for Molecular Communications." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG042.

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Avec une capacité améliorée à manipuler la matière aux échelles nano et micro via des techniques biologiques et chimiques synthétiques, il existe de nouvelles opportunités pour relever des défis allant du diagnostic et du traitement des maladies à la protection de l'environnement. Un cadre clé pour développer ces outils est le nano-réseau, où les réseaux sont constitués de dispositifs à l'échelle nanométrique qui fonctionnent dans des environnements à l'échelle nanométrique à micrométrique et effectuent des tâches simples telles que la détection et l'actionnement. L'efficacité du nano-réseau d
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Noël, Alba. "Obtention de composés azotés bioactifs d'origine naturelle : étude de biotransformation par des bactéries associées aux lichens." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1S127/document.

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Il est plus que nécessaire aujourd'hui d'apporter de nouvelles avancées dans le domaine des traitements anti-cancéreux. Il est également bien établi que dans la famille des produits bioactifs d'origine naturelle, les composés azotés sont largement représentés et ce dans la plupart des classes thérapeutiques. Aussi, ces travaux se sont concentrés sur l'obtention de composés azotés bioactifs d'origine naturelle en ciblant des produits cytotoxiques. Ce travail est divisé en trois parties. Tout d'abord, nous avons choisi d'étudier les souches bactériennes associées aux lichens. En effet, le réseau
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