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Journal articles on the topic 'Molecular epidemiology'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 July 2025

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1

Bauchet, Luc, and Quinn T. Ostrom. "Epidemiology and Molecular Epidemiology." Neurosurgery Clinics of North America 30, no. 1 (2019): 1–16. http://dx.doi.org/10.1016/j.nec.2018.08.010.

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2

Mathema, Barun, Natalia E. Kurepina, Pablo J. Bifani, and Barry N. Kreiswirth. "Molecular Epidemiology of Tuberculosis: Current Insights." Clinical Microbiology Reviews 19, no. 4 (2006): 658–85. http://dx.doi.org/10.1128/cmr.00061-05.

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SUMMARY Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing molecular techniques to address short- and long-term epidemiologic questions, such as in outbreak investigations and in assessing the global dissemination of strains, respectively. This is done primarily by examining the extent of genetic diversity of clinical strains of Mycobacterium tuberculosis. When molecular methods are used in conjunction with classical epidemiology, their utility for TB control has been realized. For instance, molecular epidemiologic studies have added much-needed accuracy and precision in describing transmission dynamics, and they have facilitated investigation of previously unresolved issues, such as estimates of recent-versus-reactive disease and the extent of exogenous reinfection. In addition, there is mounting evidence to suggest that specific strains of M. tuberculosis belonging to discrete phylogenetic clusters (lineages) may differ in virulence, pathogenesis, and epidemiologic characteristics, all of which may significantly impact TB control and vaccine development strategies. Here, we review the current methods, concepts, and applications of molecular approaches used to better understand the epidemiology of TB.

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3

Rundle, Andrew. "Molecular Epidemiology of Physical Activity and Cancer." Cancer Epidemiology, Biomarkers & Prevention 14, no. 1 (2005): 227–36. http://dx.doi.org/10.1158/1055-9965.227.14.1.

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Abstract As in other areas of epidemiology, researchers studying physical activity and cancer have begun to include laboratory analyses of biological specimens in their studies. The incorporation of these “biomarkers” into epidemiology has been termed molecular epidemiology and is an approach primarily developed to study chemical carcinogens. Thus far, there has been no discussion in the field on how the established molecular epidemiologic framework might be adapted for research into physical activity, what methodologic needs exist, what the goals of such an approach might be, and what limitations exist. This article relates the literature on molecular epidemiology to the needs of physical activity research and tries to set research priorities for the field as it moves in this new direction. Although this approach will be very useful for investigating the mechanisms through which physical activity exerts effects, there are several challenges for physical activity epidemiologists in adapting molecular epidemiologic approaches. Primarily, there are currently no available biomarkers that might be considered measures of exposure or biologically effective dose. In addition, most available biomarkers of intermediate effects have been tested in training studies at activity levels much higher than those seen in population-based epidemiologic studies. Thus, it is not clear whether these biomarkers are valid at lower activity levels. Furthermore, the nature of the relationship between activity and many available biomarkers depends very much on the context of the activity. Addressing these issues should be a priority if we are to develop a molecular epidemiologic paradigm for studying physical activity.

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4

Wilcox, Alien J. "Molecular Epidemiology." Epidemiology 6, no. 5 (1995): 561–62. http://dx.doi.org/10.1097/00001648-199509000-00019.

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5

Boffetta, P. "Molecular epidemiology." Journal of Internal Medicine 248, no. 6 (2000): 447–54. http://dx.doi.org/10.1046/j.1365-2796.2000.00777.x.

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6

Boffetta, P. "Molecular epidemiology." Journal of Internal Medicine 249, S741 (2001): 129–36. http://dx.doi.org/10.1046/j.1365-2796.2001.00777.x.

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7

Boffetta, P. "Molecular epidemiology." Journal of Internal Medicine 248, no. 6 (2008): 447–54. http://dx.doi.org/10.1111/j.1365-2796.2000.00777.x.

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8

Nishi, Akihiro, Ichiro Kawachi, Karestan C. Koenen, Kana Wu, Reiko Nishihara, and Shuji Ogino. "Lifecourse Epidemiology and Molecular Pathological Epidemiology." American Journal of Preventive Medicine 48, no. 1 (2015): 116–19. http://dx.doi.org/10.1016/j.amepre.2014.09.031.

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9

Najafzadeh, Mohammad Javad, Jiufeng Sun, Vania A. Vicente, et al. "Molecular Epidemiology ofFonsecaeaSpecies." Emerging Infectious Diseases 17, no. 3 (2011): 464–69. http://dx.doi.org/10.3201/eid1703.100555.

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10

Brady, R. C. "Meningococcal Molecular Epidemiology." AAP Grand Rounds 34, no. 3 (2015): 26. http://dx.doi.org/10.1542/gr.34-3-26.

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11

Bie, L., G. Zhao, M. McClland, et al. "LAB-MOLECULAR EPIDEMIOLOGY." Neuro-Oncology 14, suppl 6 (2012): vi50—vi52. http://dx.doi.org/10.1093/neuonc/nos225.

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12

Hayes, Richard B., Kirsti Husgafvel-Pursiainen, and Harri Vainio. "Molecular epidemiology: Convergence between toxicology and epidemiology." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 592, no. 1-2 (2005): 1–2. http://dx.doi.org/10.1016/j.mrfmmm.2005.05.009.

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13

Pfaller, Michael A. "Molecular Epidemiology in the Care of Patients." Archives of Pathology & Laboratory Medicine 123, no. 11 (1999): 1007–10. http://dx.doi.org/10.5858/1999-123-1007-meitco.

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Abstract Several different epidemiologic typing methods have been applied in studies of microbial pathogens. These methods include the more traditional nonmolecular approaches as well as the more sophisticated molecular typing methods. Application of traditional epidemiologic typing methods, such as antibiogram, serotyping, biotyping, and phage typing, have occasionally been useful in describing the epidemiology of infectious diseases. However, these methods have generally been considered to be too variable, labor intensive, and slow to be of practical value in epidemiologic investigations. In response to these limitations, several techniques have been adopted from the molecular biology field for use as epidemiologic typing methods and have been applied in studies of bacteria, fungi, viruses, and protozoa. The most widely used molecular typing methods are the DNA-based methods, such as plasmid profiling, restriction endonuclease analysis of plasmid and genomic DNA, Southern hybridization analysis using specific DNA probes, and chromosomal DNA profiling using either pulsed-field gel electrophoresis or polymerase chain reaction–based methods. The various molecular typing methods may be applied to the investigation of outbreaks of infections or may be used in the context of epidemiologic surveillance. For outbreak investigation, typing methods are used to compare isolates from a suspected outbreak to delineate clonally related and unrelated strains with the goal of short-term control of transmission. In the context of epidemiologic surveillance, molecular typing methods may be used to monitor geographic spread and prevalence shifts of epidemic and endemic clones with the goal of long-term evaluation of preventive strategies or for the detection and monitoring of emerging and reemerging infections. The specific typing method selected may vary with the task at hand; however, the typing studies must always be used to supplement, rather than replace, careful epidemiologic investigation.

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14

Chen, Y. C., and D. J. Hunter. "Molecular Epidemiology of Cancer." CA: A Cancer Journal for Clinicians 55, no. 1 (2005): 45–54. http://dx.doi.org/10.3322/canjclin.55.1.45.

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15

Yang, Zhenhua. "Molecular epidemiology of tuberculosis." Frontiers in Bioscience 8, no. 4 (2003): d440–450. http://dx.doi.org/10.2741/1024.

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16

Barnes, Peter F., and M. Donald Cave. "Molecular Epidemiology of Tuberculosis." New England Journal of Medicine 349, no. 12 (2003): 1149–56. http://dx.doi.org/10.1056/nejmra021964.

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17

Ioannidis, J. P. A. "Genetic and molecular epidemiology." Journal of Epidemiology & Community Health 61, no. 9 (2007): 757–58. http://dx.doi.org/10.1136/jech.2006.059055.

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18

John, Joseph F., and William R. Jarvis. "Enterobacter Plasmids: Molecular Epidemiology." Infection Control and Hospital Epidemiology 16, no. 2 (1995): 63. http://dx.doi.org/10.2307/30140941.

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19

Conway, David J. "Molecular Epidemiology of Malaria." Clinical Microbiology Reviews 20, no. 1 (2007): 188–204. http://dx.doi.org/10.1128/cmr.00021-06.

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SUMMARY Malaria persists as an undiminished global problem, but the resources available to address it have increased. Many tools for understanding its biology and epidemiology are well developed, with a particular richness of comparative genome sequences. Targeted genetic manipulation is now effectively combined with in vitro culture assays on the most important human parasite, Plasmodium falciparum, and with in vivo analysis of rodent and monkey malaria parasites in their laboratory hosts. Studies of the epidemiology, prevention, and treatment of human malaria have already been influenced by the availability of molecular methods, and analyses of parasite polymorphisms have long had useful and highly informative applications. However, the molecular epidemiology of malaria is currently undergoing its most substantial revolution as a result of the genomic information and technologies that are available in well-resourced centers. It is a challenge for research agendas to face the real needs presented by a disease that largely exists in extremely resource-poor settings, but it is one that there appears to be an increased willingness to undertake. To this end, developments in the molecular epidemiology of malaria are reviewed here, emphasizing aspects that may be current and future priorities.

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20

Sarafian, S. K., and J. S. Knapp. "Molecular epidemiology of gonorrhea." Clinical Microbiology Reviews 2, Suppl (1989): S49—S55. http://dx.doi.org/10.1128/cmr.2.suppl.s49.

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21

Sarafian, S. K., and J. S. Knapp. "Molecular epidemiology of gonorrhea." Clinical Microbiology Reviews 2, Suppl (1989): S49—S55. http://dx.doi.org/10.1128/cmr.2.suppl.s49-s55.1989.

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22

TACKET, CAROL O. "MOLECULAR EPIDEMIOLOGY OF SALMONELLA." Epidemiologic Reviews 11, no. 1 (1989): 99–108. http://dx.doi.org/10.1093/oxfordjournals.epirev.a036047.

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23

Fredriksson-Ahomaa, Maria, Andreas Stolle, and Hannu Korkeala. "Molecular epidemiology ofYersinia enterocoliticainfections." FEMS Immunology & Medical Microbiology 47, no. 3 (2006): 315–29. http://dx.doi.org/10.1111/j.1574-695x.2006.00095.x.

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24

De Flora, Silvio, Alberto Izzotti, Debra Walsh, Paolo Degan, Gian Luigi Petrilli, and Joellen Lewtas. "Molecular epidemiology of atherosclerosis." FASEB Journal 11, no. 12 (1997): 1021–31. http://dx.doi.org/10.1096/fasebj.11.12.9337155.

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25

Popovic, Tanja, Izabella K. Mazurova, Androulla Efstratiou, et al. "Molecular Epidemiology of Diphtheria." Journal of Infectious Diseases 181, s1 (2000): S168—S177. http://dx.doi.org/10.1086/315556.

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26

Zaridze, D. G. "Molecular epidemiology of cancer." Biochemistry (Moscow) 73, no. 5 (2008): 532–42. http://dx.doi.org/10.1134/s0006297908050064.

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27

Franzetti, F., F. Zanini, L. Gazzola, L. Codecasa, and A. Gori. "Molecular Epidemiology of Tuberculosis." Clinical Infectious Diseases 42, no. 10 (2006): 1498–99. http://dx.doi.org/10.1086/503683.

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28

John, Joseph F., and William R. Jarvis. "Enterobacter Plasmids: Molecular Epidemiology." Infection Control and Hospital Epidemiology 16, no. 2 (1995): 63. http://dx.doi.org/10.1086/647055.

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29

Burgos, M. V., and A. S. Pym. "Molecular epidemiology of tuberculosis." European Respiratory Journal 20, Supplement 36 (2002): 54S—65s. http://dx.doi.org/10.1183/09031936.02.00400702.

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30

ADLER, STUART P. "Molecular epidemiology of cytomegalovirus." Pediatric Infectious Disease Journal 5, no. 3 (1986): 315–18. http://dx.doi.org/10.1097/00006454-198605000-00008.

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31

ADLER, STUART P. "Molecular epidemiology of cytomegalovirus." Pediatric Infectious Disease Journal 10, no. 8 (1991): 584–89. http://dx.doi.org/10.1097/00006454-199108000-00007.

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32

Dolin, P. J. "Molecular epidemiology and ophthalmology." British Journal of Ophthalmology 78, no. 11 (1994): 808. http://dx.doi.org/10.1136/bjo.78.11.808.

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33

Ali, Ibne Karim M., C. Graham Clark, and William A. Petri. "Molecular epidemiology of amebiasis." Infection, Genetics and Evolution 8, no. 5 (2008): 698–707. http://dx.doi.org/10.1016/j.meegid.2008.05.004.

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34

Visseaux, Benoit, Florence Damond, Sophie Matheron, Diane Descamps, and Charlotte Charpentier. "Hiv-2 molecular epidemiology." Infection, Genetics and Evolution 46 (December 2016): 233–40. http://dx.doi.org/10.1016/j.meegid.2016.08.010.

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35

Kawaguchi, T., K. Sawa, N. Yoshimoto, K. Hirata, and P. Mack. "MS 02.02 Molecular Epidemiology." Journal of Thoracic Oncology 12, no. 11 (2017): S1669. http://dx.doi.org/10.1016/j.jtho.2017.09.201.

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36

Cacciò, Simone M., and Una Ryan. "Molecular epidemiology of giardiasis." Molecular and Biochemical Parasitology 160, no. 2 (2008): 75–80. http://dx.doi.org/10.1016/j.molbiopara.2008.04.006.

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37

Coll, Pere, and Darío García de Viedma. "Molecular epidemiology of tuberculosis." Enfermedades infecciosas y microbiologia clinica (English ed.) 36, no. 4 (2018): 233–40. http://dx.doi.org/10.1016/j.eimce.2018.01.001.

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38

Gruner, E., G. Martinetti Lucchini, R. K. Hoop, and M. Altwegg. "Molecular epidemiology ofSalmonella enteritidis." European Journal of Epidemiology 10, no. 1 (1994): 85–89. http://dx.doi.org/10.1007/bf01717458.

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39

Aldape, Kenneth D., M. Fatih Okcu, Melissa L. Bondy, and Margaret Wrensch. "Molecular Epidemiology of Glioblastoma." Cancer Journal 9, no. 2 (2003): 99–106. http://dx.doi.org/10.1097/00130404-200303000-00005.

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40

Wilson, Melissa L., Thomas Murphy Goodwin, Vivien L. Pan, and Sue Ann Ingles. "Molecular Epidemiology of Preeclampsia." Obstetrical & Gynecological Survey 58, no. 1 (2003): 39–66. http://dx.doi.org/10.1097/00006254-200301000-00022.

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41

Stevens, D. A. "Molecular Epidemiology of Candida." Journal of Clinical Microbiology 40, no. 7 (2002): 2710. http://dx.doi.org/10.1128/jcm.40.7.2710.2002.

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42

Bauer, J. "Molecular epidemiology of melanoma." Melanoma Research 20 (June 2010): e8. http://dx.doi.org/10.1097/01.cmr.0000382758.93495.d6.

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43

Cuzick, I. "Molecular epidemiology of cancer." European Journal of Cancer 29 (January 1993): S6. http://dx.doi.org/10.1016/0959-8049(93)90642-s.

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44

Kawasaki, M., H. Ishizaki, M. Miyaji, et al. "Molecular epidemiology ofCladosporium carrionii." Mycopathologia 124, no. 3 (1993): 149–52. http://dx.doi.org/10.1007/bf01103731.

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45

Kew, Olen M., Mick N. Mulders, Galina Yu Lipskaya, Edson E. da Silva, and Mark A. Patlansch. "Molecular epidemiology of polioviruses." Seminars in Virology 6, no. 6 (1995): 401–14. http://dx.doi.org/10.1016/s1044-5773(05)80017-4.

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46

Parrish, Colin R. "Molecular epidemiology of parvoviruses." Seminars in Virology 6, no. 6 (1995): 415–18. http://dx.doi.org/10.1016/s1044-5773(05)80018-6.

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47

Ludden, Catherine. "Molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli." Journal of Microbiology and Infectious Diseases 4, no. 3 (2014): 92–96. http://dx.doi.org/10.5799/ahinjs.02.2014.03.0146.

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48

Lakhashe, Samir, Madhuri Thakar, Sheela Godbole, Srikanth Tripathy, and Ramesh Paranjape. "HIV infection in India: Epidemiology, molecular epidemiology and pathogenesis." Journal of Biosciences 33, no. 4 (2008): 515–25. http://dx.doi.org/10.1007/s12038-008-0070-3.

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49

Nainan, Omana V., Guoliang Xia, Gilberto Vaughan, and Harold S. Margolis. "Diagnosis of Hepatitis A Virus Infection: a Molecular Approach." Clinical Microbiology Reviews 19, no. 1 (2006): 63–79. http://dx.doi.org/10.1128/cmr.19.1.63-79.2006.

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SUMMARY Current serologic tests provide the foundation for diagnosis of hepatitis A and hepatitis A virus (HAV) infection. Recent advances in methods to identify and characterize nucleic acid markers of viral infections have provided the foundation for the field of molecular epidemiology and increased our knowledge of the molecular biology and epidemiology of HAV. Although HAV is primarily shed in feces, there is a strong viremic phase during infection which has allowed easy access to virus isolates and the use of molecular markers to determine their genetic relatedness. Molecular epidemiologic studies have provided new information on the types and extent of HAV infection and transmission in the United States. In addition, these new diagnostic methods have provided tools for the rapid detection of food-borne HAV transmission and identification of the potential source of the food contamination.

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50

Vainio, Harri. "Promise of molecular epidemiology - epidemiologic reasoning, biological rationale and risk assessment." Scandinavian Journal of Work, Environment & Health 25, no. 6 (1999): 498–504. http://dx.doi.org/10.5271/sjweh.472.

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