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Relevant bibliographies by topics / Molecular genetic data / Dissertations / Theses

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Dissertations / Theses on the topic 'Molecular genetic data'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Liu, Kejun. "Software and Methods for Analyzing Molecular Genetic Marker Data." NCSU, 2003. http://www.lib.ncsu.edu/theses/available/etd-07182003-122001/.

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Genetic analysis of molecular markers has allowed biologists to ask a wide variety of questions. This dissertation explores some aspects of the statistical and computational issues used in the genetic marker data analysis. Chapter 1 gives an introduction to genetic marker data, as well as a brief description to each chapter. Chapter 2 presents the different genetic analyses performed on a large data set and discusses the use of microsatellites to describe the maize germplasm and to improve maize germplasm maintenance. Considerable attention is focused on how the maize germplasm is organized an

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2

Ahnert, S. E. "Implementations of information theory in molecular dynamics, quantum measurement and genetic data analysis." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.595400.

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The research presented in this thesis is divided into three topics, all of which are related to different areas of Information Theory. Firstly I have worked with my supervisor Professor Mike Payne on proposals for the implementation of two different types of quantum measurements of single photons, namely generalized measurements and weak measurements. This research belongs to the field of Quantum Information Theory. My second area of research has been Molecular Dynamics. With Gabor Csanyi I have worked on the development of a new way of constructing empirical potentials, which are needed for t

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3

Jacinto, João Miguel Antunes. "Morphological and genetic characterization of four populations of Corema album (L.) D.Don." Master's thesis, ISA/UL, 2019. http://hdl.handle.net/10400.5/18344.

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Mestrado em Engenharia Agronómica - Instituto Superior de Agronomia / UL<br>Corema album (L.) D. Don 1830, is a dioecious shrub from the Ericaceae family, that can be found in the coastal Atlantic dune systems and coastal pine tree forests of Portugal and Spain with a potential to integrate the berry market. For the first work eighty plants were sampled from Monte Clérigo, Comporta, Aldeia do Meco and Dunas de Quiaios. Six plants from Meco were chosen to follow their reproductive phenology from March to August. Finally twenty-nine morphological traits were evaluated, both from vegetative and

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4

Luo, Yuqun. "Incorporation of genetic marker information in estimating model parameters for complex traits with data from large complex pedigrees /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486549482668451.

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5

Evenstone, Lauren. "Employing Limited Next Generation Sequence Data for the Development of Genetic Loci of Phylogenetic and Population Genetic Utility." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2191.

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Massively parallel high throughput sequencers are transforming the scientific research by reducing the cost and time necessary to sequence entire genomes. The goal of this project is to produce preliminary genome assemblies of calliphorid flies using Life Technologies’ Ion Torrent sequencing and Illumina’s MiSeq sequencing. I located, assembled, and annotated a novel mitochondrial genome for one such fly, the little studied Chrysomya pacifica that is central to one hypothesis about blow fly evolution. With sequencing data from Chrysomya megacephala, its forensically relevant sister species, mu

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6

Lima, Bruno Marco de. "Bridging genomics and quantitative genetics of Eucalyptus: genome-wide prediction and genetic parameter estimation for growth and wood properties using high-density SNP data." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/11/11137/tde-25062014-085814/.

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Convergence of quantitative genetics and genomics is becoming the way that fundamental genetics and applied breeding will be carried out in the next decades. This study bridges the quantitative genetics of complex growth and wood properties traits with genomic technologies towards a more innovative approach to tree breeding. Planted forests play a major role to fulfill the growing world demand for wood products and energy. Eucalypts stand out for their high productivity and versatile wood resulting from the advanced breeding programs associated to clonal propagation and modern silviculture. De

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7

Weber-Townsend, Joshua R. "Contributions of Genetic Data to the Conservation and Management of the Threatened American Hart's-Tongue Fern (Asplenium Scolopendrium var. Americanum)." Thesis, State University of New York Col. of Environmental Science & Forestry, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10274085.

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<p> This study analyzes the range-wide genetic diversity and population structure of American hart’s-tongue fern (<i>Asplenium scolopendrium</i> var. <i>americanum</i>, AHTF), a rare fern species in the eastern United States. AHTF populations from New York, Michigan, Alabama, Tennessee, and Canada are examined using combined simple-sequence repeat and inter-simple sequence repeat markers. Genetic data provide insights on levels of genetic diversity, population structure, genetic differentiation, gene flow, total allele frequency, number of rare alleles, linkage disequilibrium and mating

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8

Mizaku, Alda. "Biomolecular feature selection of colorectal cancer microarray data using GA-SVM hybrid and noise perturbation to address overfitting." Diss., Online access via UMI:, 2009.

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Thesis (M.S.)--State University of New York at Binghamton, Thomas J. Watson School of Engineering and Applied Science, Department of Bioengineering, Biomedical Engineering, 2009.<br>Includes bibliographical references.

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9

Papakonstantinou, Dimitrios. "Genetic and transcriptomic analysis of pancreatic ductal adenocarcinoma Monocytes and macrophages as a tool to analyse patient molecular data." Electronic Thesis or Diss., université Paris-Saclay, 2025. http://www.theses.fr/2025UPASL009.

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Cette thèse de doctorat porte sur la caractérisation moléculaire de patients souffrant d'un adénocarcinome canalaire pancréatique (PDAC), une forme particulièrement agressive et mortelle de cancer.Cette recherche étudie le microenvironnement tumoral du PDAC, en mettant l'accent sur la compréhension du rôle des cellules immunitaires, notamment les macrophages, dans la biologie des tumeurs.Nous avons combiné différentes approches, notamment le profilage transcriptomique et mutationnel ainsi que la transcriptomique spatiale.Nous avons observé qu'une cohorte locale de patients atteints de PDAC pou

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10

Payne, Adrienne. "Harnessing the genetic diversity of watercess (Rorippa nasturtium-aquaticum) for improved morphology and anticancer benefits : underpinning data for molecular breeding." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/338973/.

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Watercress (Rorippa nasturtium-aquaticum) is a member of the Brassicaceae family. Increasing interest in healthy diets has turned the focus to watercress since it is known to contain one of the highest concentrations of the beneficial antioxidant phenethyl isothiocyanate (PEITC). This has exciting possibilities to breed a higher quality crop with increased concentrations of this key antioxidant providing a meachanism to aid in the prevention of cancer. Dwarfism is another desirable characteristic for many agricultural crops. A crop with a reduced stem length produces a stable increased yield a

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11

Sandling, Johanna K. "Genetic Analyses of Multiple Sclerosis and Systemic Lupus Erythematosus : From Single Markers to Genome-Wide Data." Doctoral thesis, Uppsala universitet, Molekylär medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-117776.

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In autoimmune diseases an individual’s immune system becomes targeted at the body’s own healthy cells. The aim of this thesis was to identify genetic risk factors for the two autoimmune diseases multiple sclerosis (MS) and systemic lupus erythematosus (SLE). In Study I, we found that genetic variation in the interferon regulatory factor 5 gene (IRF5), previously shown to be associated with SLE, rheumatoid arthritis and inflammatory bowel diseases, was associated also with MS. An insertion/deletion polymorphism in the first intron of IRF5 is as a good functional candidate for this association.

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12

Catanzaro, Daniele. "Models and methods for molecular phylogenetics." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210453.

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Un des buts principaux de la biologie évolutive et de la médecine moléculaire consiste à reconstruire les relations phylogénétiques entre organismes à partir de leurs séquences moléculaires. En littérature, cette question est connue sous le nom d’inférence phylogénétique et a d'importantes applications dans la recherche médicale et pharmaceutique, ainsi que dans l’immunologie, l’épidémiologie, et la dynamique des populations. L’accumulation récente de données de séquences d’ADN dans les bases de données publiques, ainsi que la facilité relative avec laquelle des données nouvelles peuvent être

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13

Csilléry, Katalin. "Statistical inference in population genetics using microsatellites." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/3865.

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Statistical inference from molecular population genetic data is currently a very active area of research for two main reasons. First, in the past two decades an enormous amount of molecular genetic data have been produced and the amount of data is expected to grow even more in the future. Second, drawing inferences about complex population genetics problems, for example understanding the demographic and genetic factors that shaped modern populations, poses a serious statistical challenge. Amongst the many different kinds of genetic data that have appeared in the past two decades, the highly po

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14

Lund, Lars H. "Regulation of gene and protein expression : two model systems /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-512-7/.

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15

Gersappe, Anand. "An analysis of genetic determinants that govern exon definition and alternative splicing of minute virus of mice (MVM) pre-mRNAs." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9904842.

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16

Rocha-Olivares, Axayácatl. "Molecular evolution, systematics, zoogeography and levels of intraspecific genetic differentiation in the species of the antitropical subgenus Sebastomus, Sebastes (Scorpaeniformes, Teleostei) using mitochondrial DNA sequence data /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p9823706.

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17

Custódio, Fábio Lima. "Algoritmos genéticos para predição ab initio de estrutura de proteínas." Laboratório Nacional de Computação Científica, 2008. http://www.lncc.br/tdmc/tde_busca/arquivo.php?codArquivo=159.

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Métodos de predição ab initio de estrutura de proteínas (PSP) buscam prever, baseando-se em primeiros princípios, a estrutura tridimensional que uma dada seqüência de aminoácidos irá adotar no espaço. Os métodos de predição ab initio atualmente possuem aplicações biotecnológicas que envolvem desde a criação de novas proteínas, o auxílio no desenho racional de fármacos (estrutura do receptor), o refinamento de modelos teóricos e a obtenção de estruturas a partir de dados experimentais incompletos. Entretanto, a predição envolve um problema de otimização que lida com milhares de graus de liberda

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18

Widerström, Micael. "Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community." Doctoral thesis, Umeå universitet, Klinisk bakteriologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-34289.

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Background Coagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). Other clinical entities due to CoNS are lower urinary tract infections (UTI) in women and native valve endocarditis. The purpose of this work was to investigate the frequency of antibiotic resistance and the molecular epidemiology of both hospital and community-associated isolates of S. epiderm

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19

Santos-Ciminera, Patricia Dantas Ciminera Patricia Dantas Santos Santos Patricia. "Molecular epidemiology of epidemic severe malaria caused by Plasmodium vivax in the state of Amazonas, Brazil /." Download the dissertation in PDF, 2005. http://www.lrc.usuhs.mil/dissertations/pdf/Santos2005.pdf.

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20

Giollo, Manuel. "Computational Approaches to Address the Next-Generation Sequencing Era." Doctoral thesis, Università degli studi di Padova, 2015. http://hdl.handle.net/11577/3424280.

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In this thesis, I propose new algorithms and models to address biological problems. Computer science in fact plays a key role in proteomics and genetics research due to the advent of big datasets. In the context of protein study, I developed new methods for protein function prediction based on information retrieval principles. By using heterogeneous source of knowledge, like graph search and sequence similarity, I designed a tool called INGA that can be used to annotate entire genomes. It has been benchmarked during the Critical Assessment of Function Annotation challenge, and it proved to be

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21

Schlee, Matthias [Verfasser], and Vera [Akademischer Betreuer] Hemleben. "Classification of taxonomic units for biology and conservation in the cases of Lathyrus pannonicus and Oxytropis pilosa - Evaluation of morphological and phytosociological studies integrating molecular genetic data / Matthias Schlee ; Betreuer: Vera Hemleben." Tübingen : Universitätsbibliothek Tübingen, 2015. http://d-nb.info/1197058176/34.

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22

Maydt, Jochen. "Analysis of recombination in molecular sequence data." Aachen Shaker, 2008. http://d-nb.info/993318045/04.

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23

Reynolds, Robert. "Gene Expression Data Analysis Using Fuzzy Logic." Fogler Library, University of Maine, 2001. http://www.library.umaine.edu/theses/pdf/REynoldsR2001.pdf.

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24

Jackson, Taryn. "Molecular and Genetic Analysis of Synaptic Signaling in Drosophila." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1356%5F1%5Fm.pdf&type=application/pdf.

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25

Marín, de Mas Igor Bartolomé. "Development and application of novel model-driven and data-driven approaches to study metabolism in the framework of systems medicine." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/296313.

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The general aim of this thesis is to develop and apply new computational tools to overcome existing limitations in the analysis of metabolism. This thesis is focused on developing new computational strategies to overcome the following identified limitations: i) The existing metabolic flux analysis tools does not account for the existence of metabolic channeling: Here we developed a new computational tool based on non-stationary 13 C-FBA to evaluate different models reflecting different topologies of intracellular metabolism, using the channeling in hepatocytes as case of concep ii) M

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26

Halladjian, Sarkis. "Spatially Integrated Abstraction of Genetic Molecules." Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG056.

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Le génome humain est principalement constitué d'ADN, une macromolécule constituée d'une longue séquence linéaire de bases, étroitement serrée pour s'insérer dans le noyau relativement petit. L'empaquetage donne lieu à de multiples niveaux hiérarchiques d'organisation. Des recherches récentes ont montré que, parallèlement à la séquence linéaire, l'agencement spatial du génome joue un rôle important dans la fonction et l'activité du génome. La visualisation des aspects li-né-aires et spatiaux des données du génome est donc nécessaire. Dans cette thèse, nous nous concentrons sur le concept d'abst

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27

桂宏胜 and Hongsheng Gui. "Data mining of post genome-wide association studies and next generation sequencing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193431.

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28

Bauer-Mehren, Anna. "Integrative approaches to investigate the molecular basis of diseases and adverse drug reactions: from multivariate statistical analysis to systems biology." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7219.

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Despite some great success, many human diseases cannot be effectively treated, prevented or cured, yet. Moreover, prescribed drugs are often not very efficient and cause undesired side effects. Hence, there is a need to investigate the molecular basis of diseases and adverse drug reactions in more detail. For this purpose, relevant biomedical data needs to be gathered, integrated and analysed in a meaningful way. In this regard, we have developed novel integrative analysis approaches based on both perspectives, classical multivariate statistics and systems biology. A novel multilevel statistic

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29

Salviato, Elisa. "Computational methods for the discovery of molecular signatures from Omics Data." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3421961.

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Molecular biomarkers, derived from high-throughput technologies, are the foundations of the "next-generation" precision medicine. Despite a decade of intense efforts and investments, the number of clinically valid biomarkers is modest. Indeed, the "big-data" nature of omics data provides new challenges that require an improvement in the strategies of data analysis and interpretation. In this thesis, two themes are proposed, both aimed at improving the statistical and computational methodology in the field of signatures discovery. The first work aim at identifying serum miRNAs to be used as di

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30

Treviño, Alvarado Victor Manuel. "Identifying the molecular components that matter : a statistical modelling approach to linking functional genomics data to cell physiology." Thesis, University of Birmingham, 2007. http://etheses.bham.ac.uk//id/eprint/636/.

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Functional genomics technologies, in which thousands of mRNAs, proteins, or metabolites can be measured in single experiments, have contributed to reshape biological investigations. One of the most important issues in the analysis of the generated large datasets is the selection of relatively small sub-sets of variables that are predictive of the physiological state of a cell or tissue. In this thesis, a truly multivariate variable selection framework using diverse functional genomics data has been developed, characterized, and tested. This framework has also been used to prove that it is poss

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31

O'Grady, Patrick M. II 1971. "Phylogenetic relationships of files in the family Drosophilidae inferred by combined analysis of molecular and morphological data sets." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/288837.

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The phylogenetic relationships of flies within the family Drosophilidae are studied in four clades placed at three different taxonomic levels. The goal of examining phylogenetic relationships of nested clades within Drosophilidae is to study patterns divergence at several points, giving a more informative view of evolution in this family of flies. Two studies presented here examine the phylogenetic relationships within the Drosophila saltans and Drosophila obscura species groups. Another examines the relationships among several species groups within the subgenus Sophophora. The final study exa

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32

Al-Mamari, Al-Ghaliya Humaid. "Application of genomics and molecular genetics in date palm (Phoenix dactylifera L.)." Thesis, University of Nottingham, 2013. http://eprints.nottingham.ac.uk/27894/.

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Date palm (Phoenix dactylifera L.) is a diploid with 18 pairs of chromosomes and an estimated genome size of 658 Mb. It is a dioecious perennial monocot, with a long generation time (a period of 4-5 years until first flowering). Date palm is one of the major fruit crops grown in the Gulf countries and particularly in the Sultanate of Oman. Approximately 250 varieties of date palm are recorded throughout the country with evaluation and characterization based on morphological and reproductive traits (e.g. fruit color, fruit shape and fruit weight). Limited molecular characterization work has bee

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33

Hurme, P. (Päivi). "Genetic basis of adaptation: bud set date and frost hardiness variation in Scots pine." Doctoral thesis, University of Oulu, 1999. http://urn.fi/urn:isbn:9514255046.

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Abstract The genetic basis of large adaptive differences in timing of bud set and frost hardiness between natural populations of Scots pine (Pinus sylvestris L.) was studied with the aid of RAPD markers and quantitative genetic tools. Steep clinal variation was found for both traits among Finnish Scots pine populations, and the differences between populations were found to be largely genetic. QTL mapping with Bayesian analysis revealed four potential QTLs for timing of bud set, and seven for frost hardiness. The QTLs were mostly different between the two traits. The potential QTLs included loc

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34

Roecklein, Kathryn Ariel. "Melanopsin polymorphisms in seasonal affective disorder /." Download the thesis in PDF, 2005. http://www.lrc.usuhs.mil/dissertations/pdf/Roecklein2005.pdf.

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35

Aken, Bronwen Louise. "Stress-inducible protein 1 : a bioinformatic analysis of the human, mouse and yeast STI1 gene structure /." Thesis, Rhodes University, 2005. http://eprints.ru.ac.za/160/.

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Thesis (M. Sc. (Biochemistry, Microbiology and Biotechnology))--Rhodes University, 2005.<br>A research report submitted in partial fulfilment of the requirements for the degree of Master of Science (in Bioinformatics and Computational Molecular Biology).

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36

Vogel, Laura Sanders. "The decline of Fowler's Toad (Bufo fowleri) in southern Louisiana: molecular genetics, field experiments and landscape studies." ScholarWorks@UNO, 2007. http://scholarworks.uno.edu/td/579.

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Two of the most pervasive threats to species biodiversity are invasive species and habitat loss and degradation. Invasive species are often relatively insensitive to disturbance and many expand their range into disturbed and fragmented habitats. This dissertation uses an interdisciplinary approach to investigate how anthropogenic habitat disturbance is precipitating a range expansion in an invasive toad species, Bufo nebulifer, which is driving a decline in its native congener, B. fowleri. I employed a remote sensing and GIS study using historical data to compare changes in the two species dis

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37

Wang, Wei. "Unveiling Molecular Mechanisms of piRNA Pathway from Small Signals in Big Data: A Dissertation." eScholarship@UMMS, 2015. https://escholarship.umassmed.edu/gsbs_diss/805.

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PIWI-interacting RNAs (piRNA) are a group of 23–35 nucleotide (nt) short RNAs that protect animal gonads from transposon activities. In Drosophila germ line, piRNAs can be categorized into two different categories— primary and secondary piRNAs— based on their origins. Primary piRNAs, generated from transcripts of specific genomic regions called piRNA clusters, which are enriched in transposon fragments that are unlikely to retain transposition activity. The transcription and maturation of primary piRNAs from those cluster transcripts are poorly understood. After being produced, a group of prim

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Wang, Wei. "Unveiling Molecular Mechanisms of piRNA Pathway from Small Signals in Big Data: A Dissertation." eScholarship@UMMS, 2010. http://escholarship.umassmed.edu/gsbs_diss/805.

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PIWI-interacting RNAs (piRNA) are a group of 23–35 nucleotide (nt) short RNAs that protect animal gonads from transposon activities. In Drosophila germ line, piRNAs can be categorized into two different categories— primary and secondary piRNAs— based on their origins. Primary piRNAs, generated from transcripts of specific genomic regions called piRNA clusters, which are enriched in transposon fragments that are unlikely to retain transposition activity. The transcription and maturation of primary piRNAs from those cluster transcripts are poorly understood. After being produced, a group of prim

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39

Simms, Amy Nicole. "Examination of Neisseria gonorrhoeae opacity protein expression during experimental murine genital tract infection /." Download the dissertation in PDF, 2005. http://www.lrc.usuhs.mil/dissertations/pdf/Simms2005.pdf.

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40

Truong, Van Chi Cong Verfasser], Eildert [Akademischer Betreuer] [Groeneveld, and Burkhard [Akademischer Betreuer] Morgenstern. "MolabIS: A Labs Backbone for Storing, Managing and Evaluating Molecular Genetics Data / Van Chi Cong Truong. Gutachter: Burkhard Morgenstern ; Eildert Groeneveld. Betreuer: Eildert Groeneveld." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2014. http://d-nb.info/1051530156/34.

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41

Giudice, Aurelio. "Basi di conoscenza e tecniche di Data Mining con applicazioni agli RNA non codificanti." Thesis, Università degli Studi di Catania, 2011. http://hdl.handle.net/10761/187.

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La tesi di Dottorato descrive l'applicazione web denominata miRo', sviluppata nell'ambito delle attivita' di dottorato svolte. miRo' e' una base di conoscenza per l'annotazione funzionale di microRNA e molecole di RNA non codificante coinvolte nella regolazione genica post-trascrizionale. Nella sua prima edizione, miRo' permetteva l'associazione di microRNA con processi e funzioni biologiche nonche' patologie che li coinvolgono attraverso le annotazioni funzionali dei geni da essi regolati. Questo tipo di tool si e' dimostrato utilissimo per la ricerca biologica di base e, soprattutto, biomed

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42

Haut, Donald David. "Small intron definition of MVM pre-mRNAs." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9904845.

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43

Villand, Julie M. "Comparison of molecular marker and morphological data to determine genetic distance among tomato cultivars." 1995. http://catalog.hathitrust.org/api/volumes/oclc/35111425.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 1995.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 42-46).

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Chen, Yi-Wen, and 陳逸文. "Genetic Variation of the Greater Bandicoot Rat (Bandicota indica) in Taiwan Based on Molecular Data." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/70837178247872629118.

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碩士<br>東海大學<br>生命科學系<br>97<br>Abstract Bandicota indica is the largest muridae animal distributed in Southeast Asia, and also the biggest rodent generally habitat at lower elevation area in Taiwan. Swinhoe (1870) speculated that this rat had been introduced to Taiwan by the Dutch in the 17th century, but lacking the historical evidence. From the view of the genetics, species colonize a new environment should affect by the founder effect or the bottleneck effect, exhibiting a lower genetic diversity. The evolutionary history of the species could be traced by understand the genetic variations,

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Yen, ChengEn, and 顏呈恩. "Studies of Genetic Diversity and the Establish of the Molecular Data Base of Taiwan Tea Cultivars." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/02918125240167409716.

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碩士<br>大葉大學<br>生物產業科技學系<br>99<br>In this study, different tea varieties preserved in Taitung Tea Research and Extension Station (TTES) were used as materials. Tea leaves were manufactured to green tea and 10 kinds of tea catechins were determined by HPLC, and to study the genes Diversity based on these chemical markers. Principal component analysis and UPGMA clustering analysis based on the contents of tea catechins have been used in the study of correlations between manufacturing suitabilities and agronomic traits. Molecular markers, including the nucleotide sequences of pITS2, trnL intron, tr

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Chen, Shuo-Wei, and 陳碩偉. "Investigating the Genome-wide Genetic- and Epigenetic- Networks for the Molecular Mechanisms of Colorectal Cancer Development via Big Data Mining and System Identification via high throughput Data." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/cs37tj.

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Hlokwe, Motlatso Tiny. "Molecular characterization of Mycobacterium bovis from livestock and wildlife in South Africa : genetic marker optimization and identification using whole genome sequence data." Thesis, 2014. http://hdl.handle.net/2263/56593.

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Bovine tuberculosis (BTB) is a disease caused by Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex, which are bacteria that infect both domestic and wildlife host species. The zoonotic nature of the disease is of great concern globally. Over 50 million animals are infected all over the world, resulting in economic losses of approximately three billion United States dollars per year. Molecular typing techniques have greatly improved knowledge regarding the sources and modes of BTB transmission in many countries including South Africa. The current study was aimed at filling

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Wu, Po-Yi, and 吳柏毅. "Constructing the Genome-wide Genetic and Epigenetic Networks for Investigating the Molecular Mechanisms of Breast Cancer Development by Big Database Mining and NGS Data Identification." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/882vkp.

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Lin, Chien-Yu, and 林建佑. "Constructing the Genetic and Epigenetic Networks for Investigating the Molecular Progression Mechanisms of Papillary Thyroid Cancer Development via Big Database Mining and NGS Data Identification." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/zr975k.

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(8775917), Mengmeng Zhu. "SEARCHING THE EDGES OF THE PROTEIN UNIVERSE USING DATA SCIENCE." Thesis, 2020.

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Abstract:

<p>Data science uses the latest techniques in statistics and machine learning to extract insights from data. With the increasing amount of protein data, a number of novel research approaches have become feasible.</p><p>Micropeptides are an emerging field in the protein universe. They are small proteins with <= 100 amino acid residues (aa) and are translated from small open reading frames (sORFs) of <= 303 base pairs (bp). Traditionally, their existence was ignored because of the technical difficulties in isolating them. With technological advances, a growing number of micropeptides have been c

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