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Journal articles on the topic 'Molecular probes'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Bubien, James K., and Dale J. Benos. "Molecular pH Probes." Circulation Research 99, no. 5 (2006): 453–54. http://dx.doi.org/10.1161/01.res.0000241052.33145.54.

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2

Zhang, Yujin, and Wei Hu. "Sensing Performance and Efficiency of Two Energy Transfer-Based Two-Photon Fluorescent Probes for pH." Sensors 18, no. 12 (2018): 4407. http://dx.doi.org/10.3390/s18124407.

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The design and synthesis of fluorescent probes for monitoring pH values inside living cells have attracted great attention, due to the important role pH plays in many biological processes. In this study, the optical properties of two different two-photon fluorescent probes for pH are studied. The ratiometric sensing of the probes are theoretically illustrated. Meanwhile, the recognitional mechanisms of the probes are investigated, which shows the energy transfer process when react with H+. Specially, the calculated results demonstrate that Probe1 possesses a higher energy transfer efficiency a

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3

Mahmood, U., and L. Josephson. "Molecular MR Imaging Probes." Proceedings of the IEEE 93, no. 4 (2005): 800–808. http://dx.doi.org/10.1109/jproc.2005.844264.

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4

Strack, Rita. "Probes for molecular crowding." Nature Methods 15, no. 8 (2018): 570. http://dx.doi.org/10.1038/s41592-018-0098-8.

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5

Diwu, Zhenjun, Cailan Zhang, Dieter H. Klaubert, and Richard P. Haugland. "Fluorescent molecular probes VI." Journal of Photochemistry and Photobiology A: Chemistry 131, no. 1-3 (2000): 95–100. http://dx.doi.org/10.1016/s1010-6030(99)00240-3.

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6

Butler, John E. "Molecular probes and immunodiagnostics." Veterinary Immunology and Immunopathology 35 (February 1993): 205–12. http://dx.doi.org/10.1016/0165-2427(93)90150-3.

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7

Wood, EJ. "Molecular probes: Handbook of fluorescent probes and research chemicals." Biochemical Education 22, no. 2 (1994): 83. http://dx.doi.org/10.1016/0307-4412(94)90083-3.

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8

Kele, Péter. "Advanced molecular (bio)probes—probes that are good, better, smarter." Methods and Applications in Fluorescence 3, no. 4 (2015): 040201. http://dx.doi.org/10.1088/2050-6120/3/4/040201.

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9

Barakat, Sarah, Melike Berksöz, Pegah Zahedimaram, Sofia Piepoli, and Batu Erman. "Nanobodies as molecular imaging probes." Free Radical Biology and Medicine 182 (March 2022): 260–75. http://dx.doi.org/10.1016/j.freeradbiomed.2022.02.031.

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10

Nagano, T. "Molecular design of bioimaging probes." Seibutsu Butsuri 43, supplement (2003): S15. http://dx.doi.org/10.2142/biophys.43.s15_2.

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11

Huang, Zhen, and Roman Boulatov. "Chemomechanics with molecular force probes." Pure and Applied Chemistry 82, no. 4 (2010): 931–51. http://dx.doi.org/10.1351/pac-con-09-11-36.

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Chemomechanics is an emerging area at the interface of chemistry, materials science, physics, and biology that aims at quantitative understanding of reaction dynamics in multiscale phenomena. These are characterized by correlated directional motion at multiple length scales—from molecular to macroscopic. Examples include reactions in stressed materials, in shear flows, and at propagating interfaces, the operation of motor proteins, ion pumps, and actuating polymers, and mechanosensing. To explain the up to 1015-fold variations in reaction rates in multiscale phenomena—which are incompatible wi

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12

Cabot, Rafel, and Christopher A. Hunter. "Molecular probes of solvation phenomena." Chemical Society Reviews 41, no. 9 (2012): 3485. http://dx.doi.org/10.1039/c2cs15287h.

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13

Jacobson., Kenneth A., Daniel L., Boring Xiao-duo Ji, William Barrington, Vickram Ramkumar, and Gary L. Stiles. "Molecular Probes for Adenosine Receptors." Japanese Journal of Pharmacology 52 (1990): 8. http://dx.doi.org/10.1016/s0021-5198(19)32889-6.

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14

Zhang, Shaohua, Ling Wen, Caixia Sun, and Zhen Li. "Ultrasmall inorganic molecular imaging probes." Nanomedicine: Nanotechnology, Biology and Medicine 14, no. 5 (2018): 1786. http://dx.doi.org/10.1016/j.nano.2017.11.132.

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15

Liang, Grace, and Patricia K. Nguyen. "Molecular probes for cardiovascular imaging." Journal of Nuclear Cardiology 23, no. 4 (2016): 783–89. http://dx.doi.org/10.1007/s12350-016-0501-8.

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16

Kim, Sung Bae, and Rika Fujii. "Fabrication of molecular tension probes." MethodsX 3 (2016): 261–67. http://dx.doi.org/10.1016/j.mex.2016.03.008.

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17

Wu, Song, Edwin Chang, and Zhen Cheng. "Molecular Probes for Bioluminescence Imaging." Current Organic Synthesis 8, no. 4 (2011): 488–97. http://dx.doi.org/10.2174/157017911796117188.

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18

Meyer, E., and T. Glatzel. "Novel Probes for Molecular Electronics." Science 324, no. 5933 (2009): 1397–98. http://dx.doi.org/10.1126/science.1175869.

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19

Zhang, Shaohua, Ling Wen, Caixia Sun, and Zhen Li. "Ultrasmall inorganic molecular imaging probes." Journal of Controlled Release 259 (August 2017): e189. http://dx.doi.org/10.1016/j.jconrel.2017.03.371.

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20

Kele, Péter. "Focus on advanced molecular (bio)probes—probes that aregood, better, smarter." Methods and Applications in Fluorescence 4, no. 1 (2015): 010401. http://dx.doi.org/10.1088/2050-6120/4/1/010401.

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21

Lu, Sha, Zhiqi Dai, Yunxi Cui, and De-Ming Kong. "Recent Development of Advanced Fluorescent Molecular Probes for Organelle-Targeted Cell Imaging." Biosensors 13, no. 3 (2023): 360. http://dx.doi.org/10.3390/bios13030360.

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Fluorescent molecular probes are very powerful tools that have been generally applied in cell imaging in the research fields of biology, pathology, pharmacology, biochemistry, and medical science. In the last couple of decades, numerous molecular probes endowed with high specificity to particular organelles have been designed to illustrate intracellular images in more detail at the subcellular level. Nowadays, the development of cell biology has enabled the investigation process to go deeply into cells, even at the molecular level. Therefore, probes that can sketch a particular organelle’s loc

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22

Schreiber, Cynthia L., and Bradley D. Smith. "Molecular Imaging of Aminopeptidase N in Cancer and Angiogenesis." Contrast Media & Molecular Imaging 2018 (June 25, 2018): 1–15. http://dx.doi.org/10.1155/2018/5315172.

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This review focuses on recent advances in the molecular imaging of aminopeptidase N (APN, also known as CD13), a zinc metalloenzyme that cleaves N-terminal neutral amino acids. It is overexpressed in multiple cancer types and also on the surface of vasculature undergoing angiogenesis, making it a promising target for molecular imaging and targeted therapy. Molecular imaging probes for APN are divided into two large subgroups: reactive and nonreactive. The structures of the reactive probes (substrates) contain a reporter group that is cleaved and released by the APN enzyme. The nonreactive prob

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23

Xu, Shuai, Wenjing Pan, Zhi-Ling Song, and Lin Yuan. "Molecular Engineering of Near-Infrared Fluorescent Probes for Cell Membrane Imaging." Molecules 28, no. 4 (2023): 1906. http://dx.doi.org/10.3390/molecules28041906.

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Cell membrane (CM) is a phospholipid bilayer that maintains integrity of a whole cell and relates to many physiological and pathological processes. Developing CM imaging tools is a feasible method for visualizing membrane-related events. In recent decades, small-molecular fluorescent probes in the near-infrared (NIR) region have been pursued extensively for CM staining to investigate its functions and related events. In this review, we summarize development of such probes from the aspect of design principles, CM-targeting mechanisms and biological applications. Moreover, at the end of this rev

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24

Chen, Hongjuan, Zilong Tang, Yewen Yang, Yuanqiang Hao, and Wansong Chen. "Recent Advances in Photoswitchable Fluorescent and Colorimetric Probes." Molecules 29, no. 11 (2024): 2521. http://dx.doi.org/10.3390/molecules29112521.

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In recent years, significant advancements have been made in the research of photoswitchable probes. These probes undergo reversible structural and electronic changes upon light exposure, thus exhibiting vast potential in molecular detection, biological imaging, material science, and information storage. Through precisely engineered molecular structures, the photoswitchable probes can toggle between “on” and “off” states at specific wavelengths, enabling highly sensitive and selective detection of targeted analytes. This review systematically presents photoswitchable fluorescent and colorimetri

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25

LOVELL, JONATHAN F., and GANG ZHENG. "ACTIVATABLE SMART PROBES FOR MOLECULAR OPTICAL IMAGING AND THERAPY." Journal of Innovative Optical Health Sciences 01, no. 01 (2008): 45–61. http://dx.doi.org/10.1142/s1793545808000157.

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Recent years have seen the design and implementation of many optical activatable smart probes. These probes are activatable because they change their optical properties and are smart because they can identify specific targets. This broad class of detection agents has allowed previously unperformed visualizations, facilitating the study of diverse biomolecules including enzymes, nucleic acids, ions and reactive oxygen species. Designed to be robust in an in vivo environment, these probes have been used in tissue culture cells and in live small animals. An emerging class of smart probes has been

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26

A. Liu, Yahu, and Xuebin Liao. "Editorial (Hot Topic: Molecular Imaging Probes)." Current Organic Chemistry 17, no. 6 (2013): 563. http://dx.doi.org/10.2174/1385272811317060002.

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27

Ren, Gang, Ying Pan, and Zhen Cheng. "Molecular Probes for Malignant Melanoma Imaging." Current Pharmaceutical Biotechnology 11, no. 6 (2010): 590–602. http://dx.doi.org/10.2174/138920110792246465.

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28

Gunosewoyo, Hendra, Mark Coster, and Michael Kassiou. "Molecular Probes for P2X7 Receptor Studies." Current Medicinal Chemistry 14, no. 14 (2007): 1505–23. http://dx.doi.org/10.2174/092986707780831023.

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29

Ponyaev, Alexander I., and Jana S. Glukhova. "MOLECULAR ENGINEERING OF MECHANOFLUOROCHROME LUMINESCENT PROBES." Bulletin of the Saint Petersburg State Institute of Technology (Technical University) 59 (2021): 79–85. http://dx.doi.org/10.36807/1998-9849-2021-59-85-79-85.

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Luminescent materials – developed using appropriate molecular engineering – are capable of signaling about various irritants with high sensitivity. In particular, mechanofluorochrome materials show fluorescence emission that is sensitive to mechanical stimulation (pressure, shear, cracking, grinding). Mechanically sensitive compounds are attracting increasing interest and various molecules are synthesized that respond to mechanical stress by changing their fluorescent characteristics (emission wavelength, intensity, polarization, Stokes shift). For a deeper understanding of the relationship be

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30

Lee, Seulki, Jin Xie, and Xiaoyuan Chen. "Activatable Molecular Probes for Cancer Imaging." Current Topics in Medicinal Chemistry 10, no. 11 (2010): 1135–44. http://dx.doi.org/10.2174/156802610791384270.

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31

Qiao, Ruirui, Ran Zhu, and Mingyuan Gao. "Imaging Tumor Metastases with Molecular Probes." Current Pharmaceutical Design 21, no. 42 (2015): 6260–64. http://dx.doi.org/10.2174/1381612821666151027153943.

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32

Liu, Hongguang, Gang Ren, Zheng Miao, et al. "Molecular Optical Imaging with Radioactive Probes." PLoS ONE 5, no. 3 (2010): e9470. http://dx.doi.org/10.1371/journal.pone.0009470.

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33

Kroemer, R. T. "Molecular modelling probes: docking and scoring." Biochemical Society Transactions 31, no. 5 (2003): 980–84. http://dx.doi.org/10.1042/bst0310980.

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A general introduction to molecular modelling techniques in the area of protein–ligand interactions is given. Methods covered range from binding-site analysis to statistical treatment of sets of ligands. The main focus of this paper is on docking and scoring. After an outline of the main concepts, two specific application examples are given.

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34

Harvey, J. F. "Molecular Probes--Technology and Medical Applications." Journal of Medical Genetics 27, no. 6 (1990): 407–8. http://dx.doi.org/10.1136/jmg.27.6.407-c.

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35

Zeng, Yun, Jing Zhu, Junqing Wang, et al. "Functional probes for cardiovascular molecular imaging." Quantitative Imaging in Medicine and Surgery 8, no. 8 (2018): 838–52. http://dx.doi.org/10.21037/qims.2018.09.19.

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36

Kojima, Hirotatsu, and Tetsuo Nagano. "Cellular imaging by using molecular probes." Folia Pharmacologica Japonica 132, no. 1 (2008): 7–10. http://dx.doi.org/10.1254/fpj.132.7.

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37

Palanisamy, Ramkumar, Ashley R. Connolly, and Matt Trau. "Epiallele Quantification Using Molecular Inversion Probes." Analytical Chemistry 83, no. 7 (2011): 2631–37. http://dx.doi.org/10.1021/ac103016n.

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38

Sarder, Pinaki, Dolonchampa Maji, and Samuel Achilefu. "Molecular Probes for Fluorescence Lifetime Imaging." Bioconjugate Chemistry 26, no. 6 (2015): 963–74. http://dx.doi.org/10.1021/acs.bioconjchem.5b00167.

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39

Khanolkar, Atmaram D., Sonya L. Palmer, and Alexandros Makriyannis. "Molecular probes for the cannabinoid receptors." Chemistry and Physics of Lipids 108, no. 1-2 (2000): 37–52. http://dx.doi.org/10.1016/s0009-3084(00)00186-9.

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40

Van Noorden, Cornelis J. F. "Molecular probes in histochemistry and cytochemistry." Acta Histochemica 100, no. 4 (1998): 337. http://dx.doi.org/10.1016/s0065-1281(98)80030-5.

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41

Kevetter, Golda Anne, and Robert B. Leonard. "Molecular probes of the vestibular nerve." Brain Research 928, no. 1-2 (2002): 18–29. http://dx.doi.org/10.1016/s0006-8993(01)03264-4.

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42

Leonard, Robert B., and Golda Anne Kevetter. "Molecular probes of the vestibular nerve." Brain Research 928, no. 1-2 (2002): 8–17. http://dx.doi.org/10.1016/s0006-8993(01)03268-1.

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43

Ingham, Eileen. "Molecular and antibody probes in diagnosis." Biochemical Education 22, no. 2 (1994): 105. http://dx.doi.org/10.1016/0307-4412(94)90104-x.

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44

Albertini, Alberto. "Molecular and antibody probes in diagnosis." Trends in Biotechnology 12, no. 6 (1994): 247–48. http://dx.doi.org/10.1016/0167-7799(94)90126-0.

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45

Lin, Xin, Jin Xie, and Xiaoyuan Chen. "Protein-based tumor molecular imaging probes." Amino Acids 41, no. 5 (2010): 1013–36. http://dx.doi.org/10.1007/s00726-010-0545-z.

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46

Edlund, Hanna, and Marie Allen. "SNP typing using molecular inversion probes." Forensic Science International: Genetics Supplement Series 1, no. 1 (2008): 473–75. http://dx.doi.org/10.1016/j.fsigss.2007.11.014.

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47

Balows, Albert. "Molecular probes: Technology and medical applications." Diagnostic Microbiology and Infectious Disease 12, no. 6 (1989): 525. http://dx.doi.org/10.1016/0732-8893(89)90088-6.

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48

COUGHTRIE, MICHAEL, MICHAEL JACKSON, DAVID HARDING, ROBERT CORSER, ROBERT HUME, and BRIAN BURCHELL. "Molecular probes for human UDP-glucuronosyltransferases." Biochemical Society Transactions 16, no. 2 (1988): 157–58. http://dx.doi.org/10.1042/bst0160157.

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49

Knowles, Daniel M. "Molecular and antibody probes in diagnosis." Immunology Today 15, no. 10 (1994): 500. http://dx.doi.org/10.1016/0167-5699(94)90201-1.

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50

Jacobson, Kenneth A., Dieter Ukena, William Padgett, Kenneth L. Kirk, and John W. Daly. "Molecular probes for extracellular adenosine receptors." Biochemical Pharmacology 36, no. 10 (1987): 1697–707. http://dx.doi.org/10.1016/0006-2952(87)90056-6.

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