Relevant bibliographies by topics / Molecular subclassification

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Molecular subclassification'

Author: Grafiati
Published: 11 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Molecular subclassification"

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Tsukasaki, Kunihiro, Olivier Hermine, Ali Bazarbachi, et al. "Definition, Prognostic Factors, Treatment, and Response Criteria of Adult T-Cell Leukemia-Lymphoma: A Proposal From an International Consensus Meeting." Journal of Clinical Oncology 27, no. 3 (2009): 453–59. http://dx.doi.org/10.1200/jco.2008.18.2428.

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Adult T-cell leukemia-lymphoma (ATL) is a distinct peripheral T-lymphocytic malignancy associated with a retrovirus designated human T-cell lymphotropic virus type I (HTLV-1). The diversity in clinical features and prognosis of patients with this disease has led to its subclassification into the following four categories: acute, lymphoma, chronic, and smoldering types. The chronic and smoldering subtypes are considered indolent and are usually managed with watchful waiting until disease progression, analogous to the management of some patients with chronic lymphoid leukemia (CLL) or other indo
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Gavrish, Yu E., A. S. Artemieva, A. A. Sidoruk, et al. "MOLECULAR SUBCLASSIFICATION OF ENDOMETRIAL CANCER: AGE ASPECTS." Профилактическая и клиническая медицина, no. 2 (2023): 41–54. http://dx.doi.org/10.47843/2074-9120_2023_2_41.

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Köbel, Martin, and Eun Young Kang. "The Evolution of Ovarian Carcinoma Subclassification." Cancers 14, no. 2 (2022): 416. http://dx.doi.org/10.3390/cancers14020416.

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The phenotypically informed histotype classification remains the mainstay of ovarian carcinoma subclassification. Histotypes of ovarian epithelial neoplasms have evolved with each edition of the WHO Classification of Female Genital Tumours. The current fifth edition (2020) lists five principal histotypes: high-grade serous carcinoma (HGSC), low-grade serous carcinoma (LGSC), mucinous carcinoma (MC), endometrioid carcinoma (EC) and clear cell carcinoma (CCC). Since histotypes arise from different cells of origin, cell lineage-specific diagnostic immunohistochemical markers and histotype-specifi
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Hytiroglou, Prodromos, Paulette Bioulac-Sage, Neil D. Theise, and Christine Sempoux. "Etiology, Pathogenesis, Diagnosis, and Practical Implications of Hepatocellular Neoplasms." Cancers 14, no. 15 (2022): 3670. http://dx.doi.org/10.3390/cancers14153670.

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Hepatocellular carcinoma (HCC), a major global contributor of cancer death, usually arises in a background of chronic liver disease, as a result of molecular changes that deregulate important signal transduction pathways. Recent studies have shown that certain molecular changes of hepatocarcinogenesis are associated with clinicopathologic features and prognosis, suggesting that subclassification of HCC is practically useful. On the other hand, subclassification of hepatocellular adenomas (HCAs), a heterogenous group of neoplasms, has been well established on the basis of genotype–phenotype cor
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Effendi, Kathryn, Wit Thun Kwa, Akihisa Ueno, and Michiie Sakamoto. "The role of molecular pathology in the precision diagnosis and subclassification of hepatocellular carcinoma." Universa Medicina 41, no. 2 (2022): 194–206. http://dx.doi.org/10.18051/univmed.2022.v41.194-206.

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Hepatocellular carcinoma (HCC) remains a leading cause of cancer death worldwide despite recent advances in surveillance and therapeutic management. The outcomes for HCC patients remain poor, often as a result of late diagnosis or lack of effective treatments. Early detection and precise diagnosis are evidently crucial in improving the prognosis of HCC. However, HCC is a highly heterogeneous cancer with various clinical backgrounds and altered molecular pathways; these factors make its precise diagnosis more difficult. Approximately 25% of HCCs harbor actionable mutations, which are yet to be
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Yamamoto, Hideki, Eiji Nakada, Seiji Kawano, et al. "Abstract 1767: Molecular subclassification of gastrointestinal stromal tumors by genomic backgrounds." Cancer Research 84, no. 6_Supplement (2024): 1767. http://dx.doi.org/10.1158/1538-7445.am2024-1767.

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Abstract Gastrointestinal stromal tumors (GISTs) are the most common gastrointestinal mesenchymal tumors. While about 10% of GISTs are known to be developed from the KIT or PDGFRA gain-of-function mutations, the rest, which is the majority of GISTs, is so-called as wild-type GISTs. There are attempts to make subclassification of wild-type GISTs in syndromic or non-syndromic group as promising for understanding of heterogeneity or treatment strategy. Genomic states of succinate dehydrogenase B (SDHB) and neurofibromatosis type 1 (NF1) have been raised as candidates for subclassification of wild
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Akhtar, Mohammed, Issam A. Al-Bozom, Mohamed Ben Gashir, and Noheir M. Taha. "Intrinsic Molecular Subclassification of Urothelial Carcinoma of the Bladder." Advances In Anatomic Pathology 26, no. 4 (2019): 251–56. http://dx.doi.org/10.1097/pap.0000000000000235.

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Li, Dong, Shuho Semba, Ming Wu, and Hiroshi Yokozaki. "Molecular pathological subclassification of mucinous adenocarcinoma of the colorectum." Pathology International 55, no. 12 (2005): 766–74. http://dx.doi.org/10.1111/j.1440-1827.2005.01903.x.

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Tsuiimoto, Gozoh. "α1-adrenoceptor (α1AR) subclassification by pharmacology and molecular cloning". Japanese Journal of Pharmacology 67 (1995): 15. http://dx.doi.org/10.1016/s0021-5198(19)46039-3.

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Thompson, Emily F., Lynn Hoang, Anne Kathrin Höhn, et al. "Molecular subclassification of vulvar squamous cell carcinoma: reproducibility and prognostic significance of a novel surgical technique." International Journal of Gynecologic Cancer 32, no. 8 (2022): 977–85. http://dx.doi.org/10.1136/ijgc-2021-003251.

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ObjectivesVulvar squamous cell carcinoma is subclassified into three prognostically relevant groups: (i) human papillomavirus (HPV) associated, (ii) HPV independent p53 abnormal (mutant pattern), and (iii) HPV independent p53 wild type. Immunohistochemistry for p16 and p53 serve as surrogates for HPV viral integration and TP53 mutational status. We assessed the reproducibility of the subclassification based on p16 and p53 immunohistochemistry and evaluated the prognostic significance of vulvar squamous cell carcinoma molecular subgroups in a patient cohort treated by vulvar field resection sur
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Dissertations / Theses on the topic "Molecular subclassification"

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Schwalbe, Edward Carl. "Molecular subclassification of medulloblastoma and its utility for disease prognostication." Thesis, University of Newcastle upon Tyne, 2012. http://hdl.handle.net/10443/1388.

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Medulloblastoma is the most common malignant brain tumour of childhood. Transcriptomic classification of the disease has indicated the existence of discrete molecular subgroups of medulloblastoma, although the precise number, nature and clinical significance of these subgroups remains unclear. Two groups, characterised by activation of the WNT and SHH signalling pathways, are common to all published studies. An assay for the rapid diagnosis of medulloblastoma subgroups was therefore designed, using transcriptomic gene signatures of pathway activation for the WNT and SHH signalling pathways. Th
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Simbolo, Michele. "MULTIGENE MUTATIONAL PROFILING OF CHOLANGIOCARCINOMAS IDENTIFIES ACTIONABLE MOLECULAR SUBGROUPS." Doctoral thesis, 2015. http://hdl.handle.net/11562/898982.

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153 tumori delle vie biliari, di cui 70 colangiocarcinomi intraepatici (ICC), 57 colangiocarcinomi extraepatici (ECC) e 26 carcinomi della colecisti (GBC) sono stati valutati per le mutazioni in 56 geni utilizzando sequenziamento multigenico di ultima generazione. L'espressione di EGFR e geni coinvolti nella pathway di mTOR sono stati studiati mediante immunoistochimica. Almeno un gene mutato è stato osservato in 118/153 (77%) tumori. I geni più frequentemente coinvolti sono KRAS (28%), TP53 (18%), ARID1A (12%), IDH1 / 2 (9%), PBRM1 (9%), BAP1 (7%), e PIK3CA (7%) . Le mutazioni in IDH1 / 2 (p
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Books on the topic "Molecular subclassification"

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Weller, Michael, Michael Brada, Tai-Tong Wong, and Michael A. Vogelbaum. Astrocytic tumours: diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, and gliomatosis cerebri. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199651870.003.0003.

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Astrocytic gliomas are primary brain tumours thought to originate from neural stem or progenitor cells. They are assigned grades II, III, or IV by the World Health Organization according to degree of malignancy as defined by histology. The following molecular markers are increasingly used for diagnostic subclassification or clinical decision-making: 1p/19q co-deletion status, O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status, and isocitrate dehydrogenase 1 and 2 mutation status. Extent of resection is a favourable prognostic factor, but surgery is never curative. Radiot
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Book chapters on the topic "Molecular subclassification"

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Wickenhauser, Claudia, Daniel Bethmann, Zipei Feng, et al. "Multispectral Fluorescence Imaging Allows for Distinctive Topographic Assessment and Subclassification of Tumor-Infiltrating and Surrounding Immune Cells." In Methods in Molecular Biology. Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8979-9_2.

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Athauda, Avani, and Ian Chau. "Advances in Molecular Subclassification of Colorectal Cancer." In Advances in the Molecular Understanding of Colorectal Cancer. IntechOpen, 2019. http://dx.doi.org/10.5772/intechopen.80679.

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Argani, Pedram, and Elizabeth J. Perlman. "Pediatric renal neoplasms." In Molecular Biology and Pathology of Paediatric Cancer. Oxford University PressNew York, NY, 2003. http://dx.doi.org/10.1093/oso/9780192630797.003.0013.

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Abstract Primary renal tumors account for 6% of cancers in children, surpassed in frequency by leukemias, brain tumors, lymphomas, sarcomas, and neuroblastomas (1). Approximately 500 new pediatric renal neoplasms are diagnosed each year in the United States, over 80% of which are enrolled on a National Wilms Tumor Study (NWTS) clinical protocol (2). The NWTS was started in 1969 with the goal of optimizing therapy for children with renal neoplasms, and has met with great success. Much of this success can be attributed to the accurate subclassification of tumors on the basis of clinical and path
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Ping, Bruno. "Advances in cytopathology." In Cytopathology, edited by Behdad Shambayati. Oxford University Press, 2018. http://dx.doi.org/10.1093/hesc/9780198717362.003.0015.

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This chapter considers automated screening and what role it could undertake in a cervical screening programme. It explores the overall impact of HPV testing, the cervical cancer vaccine, and the effect they will have on the future of cervical cytology. Immunocytochemistry (ICC) has been used for a while now. The chapter considers how new markers can be used to give better diagnostic and predictive information. Molecular techniques are emerging as useful tests to be used alongside conventional cytomorphology. Many cancers have an underlying genetic cause; analysis of DNA and RNA at the molecula
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Wonnacott, S. "Characterization of nicotine receptor sites in the brain." In Nicotine Psychopharmacology. Oxford University PressNew York, NY, 1990. http://dx.doi.org/10.1093/oso/9780192616142.003.0007.

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Abstract From the earlier chapters in this volume it is recognized that nicotine exerts its principal behavioural and psychological effects by interacting with the central nervous system. This interaction at the cellular level has been discussed in the previous chapter. The target for nicotine can be further refined to the molecular level, and the present text will consider the interaction of nicotine with its specific recognition sites on neurones. In this context it is fitting that studies with nicotine led to the initial concept of a ‘receptive substance’ on the cell surface that translates
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Conference papers on the topic "Molecular subclassification"

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Thompson, EF, L. Hoang, AK Höhn, et al. "231 Molecular subclassification of vulvar squamous cell carcinoma: prognostic significance and reproducibility." In ESGO 2021 Congress. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/ijgc-2021-esgo.616.

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Bramsen, Jesper B., Mads H. Rasmussen, Halit Ongen, et al. "Abstract 2630: Integration of tumor microenvironment and molecular subclassification of colorectal cancer identifies patient subsets with poor prognosis." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2630.

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Ferreira, Nancy, Darley Ferreira, and Thais Ferreira. "GENETIC EVALUATION OF MICROCALCIFICATIONS AS A PROGNOSTIC FACTOR." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2101.

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Introduction: Breast cancer is the most recurring type of cancer among women, with reduced mortality at an initial stage of lesion. From a radiological perspective, perceived microcalcifications may be associated with histological findings such as proliferative injuries with or without atypical features and ductal carcinoma in situ. Currently, percutaneous and vacuum biopsies allow for the correlation between anatomoradiological and identification of previous lesions and those that offer the risk of cancer. No biomarker has been established to predict the risk of cancer in women diagnosed with
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