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Journal articles on the topic 'Monolaurin'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Widiyarti, Galuh, Muhammad Hanafi, and Wahyudi Priyono Soewarso. "STUDY ON THE SYNTHESIS OF MONOLAURIN AS ANTIBACTERIAL AGENT AGAINTS Staphylococcus aureus." Indonesian Journal of Chemistry 9, no. 1 (2010): 99–106. http://dx.doi.org/10.22146/ijc.21569.

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The monolaurin compound had been synthesized from lauric acid and glycerol by using sulfuric acid (H2SO4) as catalyst. The synthesis of monolaurin was done by batch esterification on the free solvent system. The esterification reaction was performed on the equivalent mol ratio between lauric acid and glycerol 1:1, in the presence of 5% H2SO4, at 130 °C, for 6 hours, produced ester compounds on 59.29%. The products of column chromatography on silica gel purification are monolaurin and dilaurin in amount of 31.05 and 4.48%, respectively. The monolaurin and dilaurin were identified by TLC, FTIR,

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2

OH, DEOG-HWAN, and DOUGLAS L. MARSHALL. "Influence of Temperature, pH, and Glycerol Monolaurate on Growth and Survival of Listeria monocytogenes1." Journal of Food Protection 56, no. 9 (1993): 744–49. http://dx.doi.org/10.4315/0362-028x-56.9.744.

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The effect of temperature, pH, and monolaurin on the growth and survival of Listeria monocytogenes in tryptic soy broth with yeast extract (TSBYE) was investigated. TSBYE medium containing 5, 6, 7, 8, or 9 μg/ml monolaurin was adjusted to pH 5.0, 5.5, or 7.0, inoculated with L. monocytogenes, and incubated at 7, 15, or 35°C. The effect of sublethal concentrations of monolaurin was measured by calculating generation times. Results indicated that temperature and pH were very important factors influencing the efficacy of monolaurin against L. monocytogenes. Bactericidal effects were observed at p

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3

Ali, Marwa M., Mohamed A. Elashry, Eman Y. Mohammady, et al. "Dietary Alpha-Monolaurin for Nile Tilapia (Oreochromis niloticus): Stimulatory Effects on Growth, Immunohematological Indices, and Immune-Related Gene Expressions." Aquaculture Research 2023 (May 11, 2023): 1–13. http://dx.doi.org/10.1155/2023/3155447.

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Alpha-monolaurin is reported to exhibit strong antiviral and antibacterial effects. This paves the way for its use as a new generation of feed additives. The experiment was carried out to examine the effects of the inclusion of alpha-monolaurin as a feed additive for Nile tilapia (Oreochromis niloticus) growth and immune response. Four diets were formulated to include alpha-monolaurin at 0, 2, 4, and 6 g alpha-monolaurin kg−1 diets and fed to the Nile tilapia (initial weight, 3.19 ± 0.11 g) for 70 days. Compared to those of the control group, the final body weight, weight gain rate, specific g

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4

Widiyarti, Galuh, and Muhammad Hanafi. "PENGARUH KONSENTRASI KATALIS DAN PERBANDINGAN MOLARITAS REAKTAN PADA SINTESIS SENYAWA." Reaktor 12, no. 2 (2008): 90. http://dx.doi.org/10.14710/reaktor.12.2.90-97.

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In the laboratory scale, the effect of the concentration of H2SO4 catalyst (1.25-6.25) (% w/w) and the equivalent mol ratio between lauric acid and glycerol (1:1; 1:2.5; 2.5:1) on the synthesis of a-monolaurin has been studied. The a-monolaurin compound has been synthesized from lauric acid and glycerol was done by batch esterification on the free solvent system. The esterification by using 5% H2SO4 catalyst and equivalent mol ratio between lauric acid and glycerol 1:2.5 produced most monolaurin, and dilaurin in amount of 31.14 and 4.42%, respectively. The monolaurin and dilaurin are identifie

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5

Seleem, Dalia, Emily Chen, Bruna Benso, Vanessa Pardi, and Ramiro M. Murata. "In vitroevaluation of antifungal activity of monolaurin againstCandida albicansbiofilms." PeerJ 4 (June 22, 2016): e2148. http://dx.doi.org/10.7717/peerj.2148.

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Monolaurin (also known as glycerol monolaurate) is a natural compound found in coconut oil and is known for its protective biological activities as an antimicrobial agent. The nature of oral candidiasis and the increased antifungal resistance demand the search for novel antifungal therapeutic agents. In this study, we examine the antifungal activity of monolaurin againstCandida albicansbiofilms (strain ATCC:SC5314/MYA2876)in vitroand investigate whether monolaurin can alter gene expression of host inflammatory cytokines, IL-1αand IL-1β. In a co-culture model, oral fibroblast cells were culture

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6

Tokarskyy, Oleksandr, and Douglas L. Marshall. "Mechanism of Synergistic Inhibition of Listeria monocytogenes Growth by Lactic Acid, Monolaurin, and Nisin." Applied and Environmental Microbiology 74, no. 23 (2008): 7126–29. http://dx.doi.org/10.1128/aem.01292-08.

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ABSTRACT The combined lactic acid, monolaurin, and nisin effects on time-to-detection (optical density at 600 nm) extension were greater (P < 0.05) than any single or paired combination effect, which demonstrates a synergistic interaction among the antimicrobials. Monolaurin exposure caused C12:0 cell membrane incorporation. Lactic acid caused increased monolaurin C12:0 membrane incorporation, while nisin had no influence. We postulate that lactic acid-enhanced monolaurin C12:0 incorporation into the cell membrane increased membrane fluidity resulting in increased nisin activity.

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7

Subroto, E., and R. Indiarto. "Bioactive monolaurin as an antimicrobial and its potential to improve the immune system and against COVID-19: a review." Food Research 4, no. 6 (2020): 2355–65. http://dx.doi.org/10.26656/fr.2017.4(6).324.

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Monolaurin is monoacylglycerol which is a bioactive lipid since it can affect the human biological systems. This review discusses the bioactive properties of monolaurin, especially its role as an antibacterial, immune system enhancement, and its ability as an antiviral so that it has the potential to fight against various viral attacks. Monolaurin can act as an antibacterial in inhibiting the growth of several pathogenic bacteria, especially gram-positive bacteria. Monolaurin is known to be able to enhance the immune system through modulation of various immune systems, controlling pro-inflamma

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8

CHAIBI, AHMED, LAHSEN H. ABABOUCH, and FRANCIS F. BUSTA. "Inhibition of Bacterial Spores and Vegetative Cells by Glycerides." Journal of Food Protection 59, no. 7 (1996): 716–22. http://dx.doi.org/10.4315/0362-028x-59.7.716.

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Monolaurin, monomyristin, monolinolein, and monolinolenin inhibited cell growth from Bacillus cereus T, Clostridium botulinum 62A, and Clostridium sporogenes PA3679 spores and vegetative cells. The inhibitory action increased in the order monolinolein monomyristin, monolaurin, monolinolenin. Monopalmitin, monostearin, and monolein had a partial effect and diglycerides and triglycerides had no effect. B. cereus T spores were more sensitive to monolaurin, monomyristin, monolinolein, and monolinolenin than vegetative cells. Spores and vegetative cells of C. botulinum 62A were similarly affected b

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9

Ngatirah, Ngatirah, Chusnul Hidayat, Endang S. Rahayu, and Tyas Utami. "Enzymatic Glycerolysis of Palm Kernel Olein-Stearin Blend for Monolaurin Synthesis as an Emulsifier and Antibacterial." Foods 11, no. 16 (2022): 2412. http://dx.doi.org/10.3390/foods11162412.

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Monolaurin is a monoacylglycerol, which can act as an emulsifier and antibacterial. Palm kernel oil is a monolaurin raw material that can be fractionated into palm kernel olein (PKOo) and palm kernel stearin (PKS). Therefore, this study prepares monolaurin through enzymatic glycerolysis of the PKOo-PKS blend. The effects of enzyme concentration, molar ratio of oil to glycerol, solvent to oil ratio, and reaction temperature on the products of glycerolysis were investigated. The best conditions were selected for further production, purification, and characterization of the monolaurin. The result

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10

BAL'A, M. FARID A., and DOUGLAS L. MARSHALL. "Use of Double-Gradient Plates To Study Combined Effects of Salt, pH, Monolaurin, and Temperature on Listeria monocytogenes†." Journal of Food Protection 59, no. 6 (1996): 601–7. http://dx.doi.org/10.4315/0362-028x-59.6.601.

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This study evaluated the combined effects of pH, NaCl, incubation temperature, and sublethal concentrations of monolaurin on the survival of Listeria monocytogenes using the double-gradient diffusion technique. L. monocytogenes tolerance to NaCl was greatest (&gt;78 g/liter) at neutral pH (6.8 to 7.2) and increased in the pH range 7.0 to 5.4 as the incubation temperature was lowered. Monolaurin at 2 μg/ml lowered the salt tolerance of L. monocytogenes to 60 g/liter independently of pH. At 4 μg of monolaurin per ml, salt tolerance was reduced to approximately 40 g/liter with no growth occur

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11

Saleh, Ahmed Ali, Bahaa El-Gharabawy, Aziza Hassan, et al. "Effect of Dietary Inclusion of Alpha-Monolaurin on the Growth Performance, Lipid Peroxidation, and Immunity Response in Broilers." Sustainability 13, no. 9 (2021): 5231. http://dx.doi.org/10.3390/su13095231.

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As the world population increases, there will be an increase in demand for poultry meat. To satisfy this requirement, sustainably will be a significant challenge as different countries in the world face different health problems. Additionally, for decades, poultry nutritionists have worked on sustainability in broiler manufacturing plants. The usage of short- and medium-chain fatty acids (MCFAs), which have positive effects as growth promoters and immunostimulants, is a pioneering way to decrease the cost of diets and improve environmentally friendly and sustainable production in this critical

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12

Sola, Daniele, Stelvio Tonello, Giuseppe Francesco Casciaro, et al. "Higher Serum Monolaurin Is Associated with a Lower Risk of COVID-19: Results from a Prospective Observational Cohort Study." International Journal of Molecular Sciences 26, no. 6 (2025): 2452. https://doi.org/10.3390/ijms26062452.

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The COVID-19 pandemic has stimulated the search for effective preventive and therapeutic agents. In recent years, many studies have considered the effects of different nutrients. This study aimed to investigate the association between serum monolaurin levels and the risk of developing COVID-19 among healthcare workers. In this prospective observational cohort study, 2712 healthcare workers from the University Hospital “Maggiore della Carità” in Novara, Italy were enrolled. Participants underwent blood sampling and were followed up for six months to evaluate the protective role of serum monolau

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13

Klevenhusen, Fenja, Stefano M. Bernasconi, Thomas B. Hofstetter, Jakov Bolotin, Carmen Kunz, and Carla R. Soliva. "Efficiency of monolaurin in mitigating ruminal methanogenesis and modifying C-isotope fractionation when incubating diets composed of either C3or C4plants in a rumen simulation technique (Rusitec) system." British Journal of Nutrition 102, no. 9 (2009): 1308–17. http://dx.doi.org/10.1017/s0007114509990262.

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Mitigation of methanogenesis in ruminants has been an important goal for several decades. Free lauric acid, known to suppress ruminal methanogenesis, has a low palatability; therefore, in the present study the aim was to evaluate the mitigation efficacy of its esterified form (monolaurin). Further,13C-isotope abundance (δ13C) and13C–12C fractionation during methanogenesis and fermentation were determined to evaluate possible microbial C-isotope preferences. Using the rumen simulation technique, four basal diets, characterised either by the C3plants grass (hay) and wheat (straw and grain), or t

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14

OH, DEOG-HWAN, and DOUGLAS L. MARSHALL. "Monolaurin and Acetic Acid Inactivation of Listeria monocytogenes Attached to Stainless Steel." Journal of Food Protection 59, no. 3 (1996): 249–52. http://dx.doi.org/10.4315/0362-028x-59.3.249.

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Individual and combined antimicrobial effects of monolaurin and acetic acid on Listeria monocytogenesplanktonic cells or stainless-steel-adherent cells were determined in order to evaluate cell viability during a 25-min exposure period at 25°C. A 107-colony-forming units (CFU)/ml population of planktonic cells was completely inactivated by the synergistic combination of 1% acetic acid with 50 or 100 μg/ml of monolaurin within 25 or 20 min, respectively. Either compound alone caused partial but incomplete inactivation within the same time periods. A population of 105 CFU/cm2 of 1-day adherent c

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15

OH, DEOG-HWAN, and DOUGLAS L. MARSHALL. "Effect of pH on the Minimum Inhibitory Concentration of Monolaurin Against Listeria monocytogenes1." Journal of Food Protection 55, no. 6 (1992): 449–52. http://dx.doi.org/10.4315/0362-028x-55.6.449.

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The effect of pH on the minimum inhibitory concentration (MIC) of glycerol monolaurate (monolaurin) against four strains of Listeria monocytogenes at 35°C in tryptic soy broth supplemented with 0.6% yeast extract was investigated. Our results demonstrate that the MIC of monolaurin was lower than MIC values reported for other common food antimicrobials such as potassium sorbate, tertiary butylhydroquinone, propyl paraben, and butylated hydroxyanisole. The MIC of monolaurin was reduced by decreasing the pH value of the medium. A 3-fold MIC reduction occurred when the pH decreased from pH 7.0 (10

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16

Abd El Fadeel, Maha Raafat, Eman M. Soliman, Ahmad Mohammad Allam, Mohamed F. ElKersh, Rehab Mahmoud Abd El-Baky, and Ahmad Mustafa. "Efficacy and durability of bovine virus diarrhea (BVD) virus killed vaccine adjuvanted with monolaurin." PLOS ONE 17, no. 7 (2022): e0269031. http://dx.doi.org/10.1371/journal.pone.0269031.

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The bovine virus diarrhea virus (BVDV) causes reproductive, enteric, and respiratory diseases. Vaccination is essential in increasing herd resistance to BVDV spread. The selection of an adjuvant is an important factor in the success of the vaccination process. Monolaurin or glycerol monolaurate is a safe compound with an immunomodulatory effect. This study aimed to evaluate the efficacy of monolaurin as a novel adjuvant. This was examined through the preparation of an inactivated BVDV (NADL strain) vaccine adjuvanted with different concentrations of monolaurin and compared with the registered

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17

Subroto, Edy, Robi Andoyo, Rossi Indiarto, Endah Wulandari, and Elgi Fadhilah Nadhirah Wadhiah. "Preparation of Solid Lipid Nanoparticle-Ferrous Sulfate by Double Emulsion Method Based on Fat Rich in Monolaurin and Stearic Acid." Nanomaterials 12, no. 17 (2022): 3054. http://dx.doi.org/10.3390/nano12173054.

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Ferrous sulfate is one type of iron that is commonly used in iron supplementation and fortification in food products, but it has low stability and an unfavorable flavor, causing its use to be limited. Encapsulation in a solid lipid nanoparticle (SLN) system is one technology that offers stable active compound protection and a good delivery system; however, a solid lipid matrix should be selected which has good health effects, such as glycerol monolaurate or monolaurin. The purpose of this study was to obtain SLN-ferrous sulfate based on stearic acid and fat rich in monolaurin. SLN-Ferrous sulf

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18

Dufour, Muriel, Janet M. Manson, Philip J. Bremer, Jean-Pierre Dufour, Gregory M. Cook, and Robin S. Simmonds. "Characterization of Monolaurin Resistance in Enterococcus faecalis." Applied and Environmental Microbiology 73, no. 17 (2007): 5507–15. http://dx.doi.org/10.1128/aem.01013-07.

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ABSTRACT There is increasing concern regarding the presence of vancomycin-resistant enterococci in domestically farmed animals, which may act as reservoirs and vehicles of transmission for drug-resistant enterococci to humans, resulting in serious infections. In order to assess the potential for the use of monolaurin as a food preservative, it is important to understand both its target and potential mechanisms of resistance. A Tn917 mutant library of Enterococcus faecalis AR01/DGVS was screened for resistance (MIC, >100 μg/ml) to monolaurin. Three mutants were identified as resistant to mon

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19

Affandi, Arief Rakhman. "KAJIAN SIFAT ANTIBAKTERI EMULSIFIER MONOLAURIN YANG DIHASILKAN DARI REAKSI KIMIAWI DAN ENZIMATIS." Jurnal Ilmu Pangan dan Hasil Pertanian 1, no. 2 (2018): 93. http://dx.doi.org/10.26877/jiphp.v1i2.2097.

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Monolaurin merupakan salah satu bentuk monogliserida yang memiliki kandungan asam laurat yang cukup tinggi. Selain dapat berfungsi sebagai emulsifier, produk ini juga memiliki sifat antibakteri yang cukup tinggi. Oleh karena itu, produk ini banyak diaplikasikan dalam dunia farmasetikal dan industri pangan. Produk monolaurin dapat dihasilkan dari berbagai sumber bahan baku yang memiliki kandungan asam laurat cukup tinggi, seperti minyak kelapa dan minyak inti sawit. Kedua jenis minyak nabati ini diketahui memiliki kandungan asam laurat sekitar 40-60%. Proses produksi dapat dilakukan secara kimi

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20

Inooka, Shoshi. "Cell ring-like objects created in agar cultures of synthetic DNA (Streptomyces) crown cells with monolaurin." Clinical Cardiology and Cardiovascular Interventions 7, no. 7 (2024): 01–08. https://doi.org/10.31579/2641-0419/362.

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Synthesized DNA crown cells (artificial cells), which can proliferate within egg white in vivo, can be prepared in vitro using sphingosine (Sph)-DNA-adenosine-monolaurin compounds. Synthesized DNA crown cells form assemblies that proliferate in the presence of monolaurin and can be observed in agar cultures. In previous experiments on synthetic DNA (E. coli/Human placenta/Ascidian) crown cells, the proliferation of objects similar in appearance to thalli, double-cells, morning glory and daffodil inflorescences was observed on agar plates. In the present experiments using synthetic DNA (Strepto

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21

Kmiha, Souhir, Chedia Aouadhi, Khouloud Aziza, Awatef Bejaoui, and Abderrazak Maaroufi. "Comparison of Synergistic Effect of Nisin and Monolaurin on the Inactivation of Three Heat Resistant Spores Studied by Design of Experiments in Milk." Journal of Food Quality 2021 (December 31, 2021): 1–13. http://dx.doi.org/10.1155/2021/9977646.

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Spore forming bacteria are special problems for the dairy industry. Heat treatments are insufficient to kill the spores. This is a continuously increasing problem for the industry, but we should be able to control it. In this context, we investigated the combined effect of nisin, monolaurin, and pH values on three heat resistant spores in UHT milk and distilled water and to select an optimal combination for the maximum spore inactivation. The inhibitory effect of nisin (between 50 and 200 IU/ml), monolaurin (ranging from 150 to 300 µg/ml), and pH (between 5 and 8) was investigated using a cent

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Pereira, Carla C. B., Mônica A. P. da Silva, and Marta A. P. Langone. "Enzymatic Synthesis of Monolaurin." Applied Biochemistry and Biotechnology 114, no. 1-3 (2004): 433–46. http://dx.doi.org/10.1385/abab:114:1-3:433.

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OH, DEOG-HWAN, and DOUGLAS L. MARSHALL. "Destruction of Listeria monocytogenes Biofilms on Stainless Steel Using Monolaurin and Heat1." Journal of Food Protection 58, no. 3 (1995): 251–55. http://dx.doi.org/10.4315/0362-028x-58.3.251.

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Individual and combined antimicrobial effects of monolaurin and heat on planktonic, 1-day adherent, or 7-day adherent cells of Listeria monocytogenes were determined to evaluate biofilm removal from stainless steel. Planktonic cells were more sensitive to heat and monolaurin than were cells attached to stainless steel. Young (1-day) biofilm cells were more sensitive to each treatment than were old (7-day) biofilm cells. Adherent cells were destroyed by 50 μg/ml monolaurin combined with heating at 65°C for 5 min. Cells in a rich nutrient environment were more resistant to treatment than were ce

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Mhatre, Jyoti D., та Pravin U. Singare. "Comparative Study on Cytotoxicity Activity of N-α-Acylarginine Ethyl Ester". International Letters of Chemistry, Physics and Astronomy 13 (вересень 2013): 1–7. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.13.1.

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Amino-acid derived compounds, for example N-α-lauroylarginine ethyl ester (LAE), N-α-myristoylarginine ethyl ester (MAE) and a 1:1 mixture of N-α-myristoylarginine ethyl ester with monolaurin (MAE + MLN) are examined for their cytotoxicity towards L929-Mouse connective tissue to explore their use as microbicidal agent, in comparison to sodium dodecylsulfate (SDS) as an anionic control detergent. MTT (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxicity assay method was used to determine IC50 value. Cytotoxicity of MAE is found to be more toxic as compared to LAE, having IC50

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Mhatre, Jyoti D., та Pravin U. Singare. "Comparative Study on Cytotoxicity Activity of N-α-Acylarginine Ethyl Ester". International Letters of Chemistry, Physics and Astronomy 13 (3 травня 2013): 1–7. http://dx.doi.org/10.56431/p-e1m6jy.

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Amino-acid derived compounds, for example N-α-lauroylarginine ethyl ester (LAE), N-α-myristoylarginine ethyl ester (MAE) and a 1:1 mixture of N-α-myristoylarginine ethyl ester with monolaurin (MAE + MLN) are examined for their cytotoxicity towards L929-Mouse connective tissue to explore their use as microbicidal agent, in comparison to sodium dodecylsulfate (SDS) as an anionic control detergent. MTT (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide cytotoxicity assay method was used to determine IC50 value. Cytotoxicity of MAE is found to be more toxic as compared to LAE, having IC50

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Castillo-Castillo, Yamicela, Marina Ontiveros, Eric J. Scholljegerdes, et al. "PSIX-18 Laurate and its glycerol monoester, monolaurin, as potential additives to control Listeria monocytogenes and tetracycline resistant Enterococcus faecalis in air-exposed silage." Journal of Animal Science 98, Supplement_4 (2020): 414–15. http://dx.doi.org/10.1093/jas/skaa278.724.

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Abstract Silages can harbor pathogenic and antimicrobial resistant microbes which risk infection of food-producing animals. Livestock producers need effective yet environmentally friendly interventions to preserve the feed value of these fermented materials. Medium chain fatty acids such as laurate and its glycerol monoester, monolaurin, are potent inhibitors of many Gram-positive bacteria and when tested at 5 mg/mL in anaerobic cultures (n = 3/treatment) inoculated with 105 colony forming units (CFU) of Listeria monocytogenes and grown at 37oC in ½ strength Brain Heart infusion broth achieved

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Ngatirah, N., C. Hidayat, ES Rahayu, and T. Utami. "Enzymatic Glycerolysis of Palm Kernel Olein and Palm Kernel Stearin in different Ratios for Monolaurin Synthesis." IOP Conference Series: Materials Science and Engineering 1192, no. 1 (2021): 012018. http://dx.doi.org/10.1088/1757-899x/1192/1/012018.

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Abstract Monolaurin is known as a monoglyceride of lauric acid, which act as an emulsifier and antimicrobial. One potential of monolaurin raw materials is palm kernel oil (PKO), which can be fractionated into palm kernel olein (PKOo) and palm kernel stearin (PKS). This study aims to determine the enzymatic glycerolysis influence of PKOo and PKS mixture in different ratios and time, on monoacylglycerol (MAG), diacylglycerol (DAG), and triacylglycerol (TAG) profiles. The Glycerolysis process of PKOo-PKS fat blends were carried out in different ratios of (60:40, 40:60, and 20:80 w/w) using commer

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Ali, Samia. "Role of monolaurin additive with medium-chain fatty acids against dextran sulfate sodium-induced acute colitis through down regulating the oxidative stress in wistar rats." Pakistan Journal of Agricultural Sciences 60, no. 02 (2023): 347–54. http://dx.doi.org/10.21162/pakjas/23.30.

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Inflammatory bowel disease (IBD) is the persistent inflammation of GIT (Gastrointestinal tract). IBD mainly divided into ulcerative colitis and Crohn’s disease while the Crohn’s disease involves the whole gastrointestinal tract while ulcerative colitis is limited to the colon. The current experimental study elucidates the antioxidative and microbial homeostatic efficacy of monolaurin, monolaurin with butyric acid and propionic acid in DSS (Dextran sulfate sodium) induced acute colitis in rat model. The results revealed that total antioxidant capacity was raised significantly (P<0.05) in all

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Thomas, Lori L., Ashley Hartman, Jason C. Woodworth, et al. "138 Evaluation of different combinations of medium chain fatty acids and monolaurin as a dietary additive for nursery pigs." Journal of Animal Science 97, Supplement_2 (2019): 80–81. http://dx.doi.org/10.1093/jas/skz122.146.

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Abstract A total of 360 pigs (DNA 400×200, initial BW=6.8 kg) were used a 35-d trial to evaluate the effects of adding MCFA and monolaurin blends to the diet on growth performance of nursery pigs. Pens of pigs were blocked by BW and randomized to 1 of 6 dietary treatments (12 pens per treatment). Treatments consisted of a basal diet containing no MCFA (control), the control diet with 1.0% added MCFA (a 1:1:1 blend of C6, C8, and C10; Sigma Aldrich, St. Louis, MO), or a 1.0% inclusion of 4 different blends of MCFA, lactic acid, and monolaurin (1, 2, 3, and 4). The 4 blends consisted of 50% C6,

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Subroto, E., R. Indiarto, A. D. Pangawikan, et al. "Melting behaviour of cocoa butter substitutes synthesised by enzymatic glycerolysis of coconut oil and palm stearin blends." Food Research 7, no. 3 (2023): 194–202. http://dx.doi.org/10.26656/fr.2017.7(3).872.

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Cocoa Butter (CB) is a speciality fat required in various products, but its availability is limited and has adverse health effects. Therefore, an alternative to CB is needed. This study aimed to synthesise cocoa butter substitutes (CBS) rich in monolaurin by enzymatic glycerolysis of coconut oil (CNO) and palm stearin (PS) blends. The ratios of CNO to PS used were 7:3, 6:4, and 5:5 (w/w). Several characteristics related to the melting behaviour of CBS were analysed. The results showed that CBS contained monoacylglycerol (MAG) and diacylglycerol (DAG) about 55.89-57.28% and 34.27-39.57%, respec

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Odel Nitbani, Febri, Jumina Jumina, Dwi Siswanta, Eti Nurwening Sholikhah, and Dhina Fitriastuti. "Synthesis and Antibacterial Activity 1-Monolaurin." Oriental Journal of Chemistry 34, no. 2 (2018): 863–67. http://dx.doi.org/10.13005/ojc/340233.

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Kang, Sini, Yaqing Guo, Junhui Rao, Hui Jin, Hyun Ju You, and Geun Eog Ji. "In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus plantarum pH3A, monolaurin, and grapefruit seed extract." Food & Function 12, no. 21 (2021): 11024–32. http://dx.doi.org/10.1039/d1fo01480c.

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Kovanda, Lauren, Wen Zhang, Xiaohong Wei, et al. "In Vitro Antimicrobial Activities of Organic Acids and Their Derivatives on Several Species of Gram-Negative and Gram-Positive Bacteria." Molecules 24, no. 20 (2019): 3770. http://dx.doi.org/10.3390/molecules24203770.

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The objective of this study was to determine the in vitro antimicrobial activity of several organic acids and their derivatives against Gram-positive (G+) and Gram-negative (G−) bacteria. Butyric acid, valeric acid, monopropionin, monobutyrin, monovalerin, monolaurin, sodium formate, and ProPhorce—a mixture of sodium formate and formic acid (40:60 w/v)—were tested at 8 to 16 concentrations from 10 to 50,000 mg/L. The tested bacteria included G− bacteria (Escherichia coli, Salmonella enterica Typhimurium, and Campylobacter jejuni) and G+ bacteria (Enterococcus faecalis, Clostridium perfringens,

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Stybel, V. V., I. K. Avdos'eva, O. I. Chaykovska, O. S. Kalinina, and S. M. Temnenko. "INNOVATIVE FEED MIXTURES FOR ANIMAL HEALTH PROTECTION." Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology 26, no. 1 (2025): 231–35. https://doi.org/10.36359/scivp.2025-26-1.26.

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To combat dangerous infectious diseases in animals, antibiotics and vaccines are widely used. However, antibiotics can cause resistance in microorganisms and the transfer of antibiotic resistance genes from animals to humans, while vaccines do not always provide long-lasting immunity and are often ineffective against new strains of infectious disease pathogens. The feed mixture LAURIT 90, containing the active substance alpha-monolaurin, is used in animal husbandry as a strong natural antibacterial and antiviral agent. The antibacterial action of alpha-monolaurin is aimed at destroying the cel

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Miao, Shanshan, and Xin Li. "Enzymatic esterification of lauric acid to give monolaurin in a microreactor." Journal of Chemical Research 45, no. 7-8 (2021): 660–67. http://dx.doi.org/10.1177/1747519820977164.

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Monolaurin is a naturally occurring compound widely utilized in food and cosmetics. In this paper, we present a new method for the synthesis of monolaurin by esterification between lauric acid and glycerol catalyzed by Novozym® 435 using a microreactor. The conversion of lauric acid is 87.04% in 20 min, compared with 70.54% via the batch approach in 5 h. Using an optimized solvent system consisting of t-BuOH/ tert-amyl alcohol (1:1, v/v), the selectivity using the microreactor method is enhanced to 90.63% and the space–time yield of the process is 380.91 g/h/L. This newly devised method has th

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Lozano, Pedro, Celia Gomez, Susana Nieto, Gregorio Sanchez-Gomez, Eduardo García-Verdugo, and Santiago V. Luis. "Highly selective biocatalytic synthesis of monoacylglycerides in sponge-like ionic liquids." Green Chemistry 19, no. 2 (2017): 390–96. http://dx.doi.org/10.1039/c6gc01969b.

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Letlole, Bakang R., Ellen P. C. W. Damen та Christine Jansen van Rensburg. "The Effect of α-Monolaurin and Butyrate Supplementation on Broiler Performance and Gut Health in the Absence and Presence of the Antibiotic Growth Promoter Zinc Bacitracin". Antibiotics 10, № 6 (2021): 651. http://dx.doi.org/10.3390/antibiotics10060651.

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The use of antibiotic growth promoters (AGP) is common practice to improve broiler production and performance. The use of AGP is under discussion as it can induce bacterial resistance. The purpose of this study was to determine the impact of removing AGP from broiler feed and study the effect of feed additives. For those countries where in-feed AGP are still permitted, the effect of the products in the presence of AGP was evaluated. Half the number of male broilers received a diet free of AGP, whereas the other half received a diet supplemented with zinc bacitracin at 0.5 g/kg. Both diets were

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Potapova, L. V., M. S. Zhuravlev, N. P. Buryakov, and Yu A. Ezerskaya. "Effect of alpha-monolaurin on perfomance of fattening pigs under industrial conditions." Agrarian science, no. 7-8 (September 24, 2021): 68–70. http://dx.doi.org/10.32634/0869-8155-2021-351-7-8-68-70.

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Relevance. Monoglycerides of organic acids are considered as a promising replacement for feed antibiotics in the diets of pigs and poultry, as they have pronounced bacteriostatic and bactericidal properties. Alpha-monolaurin is a one of the most promising compound, which has a significant antibacterial effect on gram-positive microorganisms.Methods. The experiment was carried out at one of the pig farms of the Rostov region on September 5–27, 2020 on fattening pigs weighing from 36 kg and up to achievinga live weight of 75 kg. Piglets of the experimental group received 0.4 kg/t of alpha-monola

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Nitbani, Febri, Jumina Jumina, Dwi Siswanta, Eti Sholikhah, and Dhina Fitriastuti. "Synthesis and Antibacterial Activity of 2-Monolaurin." Oriental Journal of Chemistry 32, no. 6 (2016): 3113–20. http://dx.doi.org/10.13005/ojc/320632.

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Bhalla, Shubhang, Jose Barragan, Luke Kotin, et al. "Antimicrobial Activity of Monolaurin Against Borrelia burgdorferi." Clinical Infection and Immunity 7, no. 1 (2022): 17–21. http://dx.doi.org/10.14740/cii150.

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Kanesaka, Isao, and Kunihiko Shimizu. "Infrared intensity and morphology of 1-monolaurin–water systems." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 56, no. 3 (2000): 523–29. http://dx.doi.org/10.1016/s1386-1425(99)00143-2.

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da Silva, William Franco, Debora Merediane Kochepka, Laís Pastre Dill, Fernando Wypych, and Claudiney Soares Cordeiro. "Selective synthesis of monolaurin catalyzed by layered zinc laurate." Reaction Kinetics, Mechanisms and Catalysis 128, no. 2 (2019): 779–91. http://dx.doi.org/10.1007/s11144-019-01664-z.

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Bautista, D. A., M. D. Durisin, S. M. Razavi-Rohani, A. R. Hill, and M. W. Griffiths. "Extending the shelf-life of cottage cheese using monolaurin." Food Research International 26, no. 3 (1993): 203–8. http://dx.doi.org/10.1016/0963-9969(93)90054-m.

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Goncharov, A. T., and S. V. Lenev. "Alpha-Monolaurin for prevention and treatment of avian listeriosis." "Veterinary Medicine" Journal 27, no. 01 (2024): 12–16. http://dx.doi.org/10.30896/0042-4846.2024.27.1.12-16.

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Sedlarikova, Jana, Magda Janalikova, Petra Peer, Lucie Pavlatkova, Antonin Minarik, and Pavel Pleva. "Zein-Based Films Containing Monolaurin/Eugenol or Essential Oils with Potential for Bioactive Packaging Application." International Journal of Molecular Sciences 23, no. 1 (2021): 384. http://dx.doi.org/10.3390/ijms23010384.

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Zein is renewable plant protein with valuable film-forming properties that can be used as a packaging material. It is known that the addition of natural cross-linkers can enhance a film’s tensile properties. In this study, we aimed to prepare antimicrobial zein-based films enriched with monolaurin, eugenol, oregano, and thyme essential oil. Films were prepared using the solvent casting technique from ethanol solution. Their physicochemical properties were investigated using structural, morphological, and thermal techniques. Polar and dispersive components were analyzed using two models to eval

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Thomas, Lori L., Jason C. Woodworth, Mike D. Tokach, et al. "Evaluation of different blends of medium-chain fatty acids, lactic acid, and monolaurin on nursery pig growth performance12." Translational Animal Science 4, no. 2 (2020): 548–57. http://dx.doi.org/10.1093/tas/txaa024.

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Abstract A total of 710 pigs (Line 400 × 200, DNA, Columbus, net energy (NE)) were used in two experiments (Exp. 1: initially, 6.3 ± 0.05 kg; Exp. 2: initially, 6.8 ± 0.05 kg) to evaluate the effects of two medium-chain fatty acid (MCFA) based products on nursery pig growth performance. Following their arrival at the nursery facility, pigs were randomized to pens (five pigs per pen) and allowed a 4-d acclimation period. Thereafter, pens of pigs were blocked by initial weight and randomized to dietary treatment. In Exp. 1, the dietary treatments were a dose titration of: 0%, 0.5%, 1.0%, or 2.0%

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Ontiveros-Magadan, Marina, Robin C. Anderson, Oscar Ruiz-Barrera, et al. "Evaluation of antimicrobial compounds to inhibit growth of select Gram-positive pathogenic or antimicrobial resistant bacteria in air-exposed silage." Canadian Journal of Animal Science 102, no. 1 (2022): 75–84. http://dx.doi.org/10.1139/cjas-2021-0061.

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Spoiled silages can harbor pathogenic and antimicrobial-resistant microbes. The potential of some antimicrobial additives to inhibit certain pathogenic and antimicrobial-resistant bacteria in air-exposed silage was measured using pure and mixed bacterial cultures. With pure cultures, laurate and monolaurin (5 mg·mL−1) caused decreases (P < 0.05) of 4 to >7 log10 colony-forming units (CFU)·mL−1 in Listeria monocytogenes and Enterococcus faecalis compared to controls. Ten-fold higher amounts of these inhibitors were needed to equivalently decrease staphylococci. 2-Nitropropanol (1 mg·mL−1)

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Dea Permata, Daniel Adhie Saputra, Billy Saputra Sutedjo, and Zahara Meilawaty. "Evaluating the effectiveness of coconut oil (Cocus nucifera) anti-bacterial benefits in caries prevention: A literature review." International Journal of Science and Research Archive 11, no. 2 (2024): 212–15. http://dx.doi.org/10.30574/ijsra.2024.11.2.0401.

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Background: Caries is the damage to the hard tooth tissue, which is enamel and dentine due to bacteria, with one of them being Streptococcus mutans. Caries is the most widespread non-infectious disease, with 2 billion people in the world suffering from permanent tooth caries and 514 million children suffering from primary tooth caries. The abundance of natural resources in Indonesia can be used as a way to prevent caries, such as using coconut oil which is known to have antibacterial benefits. Method: Analysis of several scientific findings and research with publication limitation over the las

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Rohani, Seyed Mehdi Razavi, and Ali Topchi. "The Effect of Monolaurin on Staphylococcus aureus and Escherichia coli." Research Journal of Biological Sciences 6, no. 12 (2011): 661–65. http://dx.doi.org/10.3923/rjbsci.2011.661.665.

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Kaewmanee, Paramaporn Chiewpattanakul, Benjamas Wongsatayanon, and Alain Durand. "Encapsulation of Bioactive Compounds (Monocaprin and Monolaurin) into Polymeric Nanoparticles." Materials Science Forum 916 (March 2018): 147–52. http://dx.doi.org/10.4028/www.scientific.net/msf.916.147.

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The dextran-covered poly (lactic acid) (PLA) polymeric nanoparticles were prepared by a nanoprecipitation process for the encapsulation of monocaprin (MC) or monolaurin (ML). The concentration of PLA/MC or ML was varied to evaluate the best condition for preparation. The miscibility of various PLA/MC or ML blends was studied using differential scanning calorimetry. The result showed that at concentrations of 50/50 wt/wt, the PLA/ML blend was partly miscible and the nanoparticle suspension produced large amounts of macroscopic aggregates after nanoprecipitation. Conversely, the miscibility of P

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