Relevant bibliographies by topics / Monoterpene indole alkaloids

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Monoterpene indole alkaloids'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Monoterpene indole alkaloids"

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Brown, Stephanie, Marc Clastre, Vincent Courdavault, and Sarah E. O’Connor. "De novo production of the plant-derived alkaloid strictosidine in yeast." Proceedings of the National Academy of Sciences 112, no. 11 (2015): 3205–10. http://dx.doi.org/10.1073/pnas.1423555112.

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The monoterpene indole alkaloids are a large group of plant-derived specialized metabolites, many of which have valuable pharmaceutical or biological activity. There are ∼3,000 monoterpene indole alkaloids produced by thousands of plant species in numerous families. The diverse chemical structures found in this metabolite class originate from strictosidine, which is the last common biosynthetic intermediate for all monoterpene indole alkaloid enzymatic pathways. Reconstitution of biosynthetic pathways in a heterologous host is a promising strategy for rapid and inexpensive production of comple
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David Phillipson, J. "Monoterpene Indole Alkaloids." Phytochemistry 38, no. 6 (1995): 1552–53. http://dx.doi.org/10.1016/0031-9422(95)90301-1.

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Schiel, Otmar, Ludger Witte, and Jochen Berlin. "Geraniol-10-hydroxylase Activity and Its Relation to Monoterpene Indole Alkaloid Accumulation in Cell Suspension Cultures of Catharanthus roseus." Zeitschrift für Naturforschung C 42, no. 9-10 (1987): 1075–81. http://dx.doi.org/10.1515/znc-1987-9-1012.

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The activity of geraniol- 10-hydroxylase was greatly increased when Catharanthus roseus cells were transferred to a production medium for monoterpene indole alkaloids. Its activity pattern showed a closer relationship than tryptophan decarboxylase to the pattern of indole alkaloid accumulation. The intermediate accumulation of tryptamine and its later incorporation into ajmalicine indicated that the coordination of the two precursor pathways for the monoterpene indole alkaloid formation was not synchronized under the chosen culture conditions. A better tuning of these two pathways may shorten
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Düsman, Lilian Tatiani, Tereza C. Marinho Jorge, Maria Conceição de Souza, et al. "Monoterpene Indole Alkaloids fromPalicoureacrocea." Journal of Natural Products 67, no. 11 (2004): 1886–88. http://dx.doi.org/10.1021/np0340807.

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Si, Ying-Ying, Wei-Wei Wang, Qing-Mei Feng, et al. "Neuroinflammatory inhibitors from Gardneria nutans Siebold & Zuccarini." RSC Advances 11, no. 44 (2021): 27085–91. http://dx.doi.org/10.1039/d1ra05204g.

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Four new compounds were isolated from G. nutans. Compounds 1–2 are two rare monoterpene indole alkaloids with the glucosyl moiety located at C-12 and represent the first two examples of enantiomer of ajmaline type monoterpene indole alkaloids.
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Tanifuji, Ryo, Atsushi Minami, Hiroki Oguri, and Hideaki Oikawa. "Total synthesis of alkaloids using both chemical and biochemical methods." Natural Product Reports 37, no. 8 (2020): 1098–121. http://dx.doi.org/10.1039/c9np00073a.

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Wang, Zhiguo, Yi Chen, Zhen Dong, and Yefeng Tang. "Natural Product-Oriented Photo-Induced Denitrogenative Annulations of 1-Alkenylbenzotriazoles." Molecules 28, no. 1 (2023): 363. http://dx.doi.org/10.3390/molecules28010363.

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The photo-induced denitrogenative annulations of a variety of 1-alkenylbenzotriazoles were investigated. By judiciously manipulating the structural variations of 1-alkenylbenzotriazoles, two characteristic polycyclic skeletons associated with monoterpene indole alkaloids were constructed through a diverted and controllable manner. The present work not only enriches the photochemistry of 1-alkenylbenzotriazoles, but also offers a unified approach to access skeletally diverse indole alkaloid scaffolds.
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Ahmed, Abrar, Wei Li, Fang-Fang Chen, et al. "Monoterpene indole alkaloids from Rhazya stricta." Fitoterapia 128 (July 2018): 1–6. http://dx.doi.org/10.1016/j.fitote.2018.04.018.

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Dusséaux, Simon, William Thomas Wajn, Yixuan Liu, Codruta Ignea, and Sotirios C. Kampranis. "Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids." Proceedings of the National Academy of Sciences 117, no. 50 (2020): 31789–99. http://dx.doi.org/10.1073/pnas.2013968117.

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Current approaches for the production of high-value compounds in microorganisms mostly use the cytosol as a general reaction vessel. However, competing pathways and metabolic cross-talk frequently prevent efficient synthesis of target compounds in the cytosol. Eukaryotic cells control the complexity of their metabolism by harnessing organelles to insulate biochemical pathways. Inspired by this concept, herein we transform yeast peroxisomes into microfactories for geranyl diphosphate-derived compounds, focusing on monoterpenoids, monoterpene indole alkaloids, and cannabinoids. We introduce a co
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Cheenpracha, Sarot, Achara Raksat, Thunwadee Ritthiwigrom, and Surat Laphookhieo. "Monoterpene Indole Alkaloids from the Twigs of Kopsia arborea." Natural Product Communications 9, no. 10 (2014): 1934578X1400901. http://dx.doi.org/10.1177/1934578x1400901010.

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The phytochemistry of Kopsia arborea Blume has received considerable attention, which has resulted in the isolation of a number of new unusual indole alkaloids with intriguing structures. In this study, a new eburnane-type alkaloid, phutdonginin (1), together with eight known alkaloids: 19-OH-(-)-eburnamonine (2), melodinine E (3), kopsinine (4), kopsilongine (5), kopsamine (6), (-)-methylenedioxy-11,12-kopsinaline (7), decarbomethoxykopsiline (8), and vincadifformine (9), were isolated from the twigs of K. arborea. Their structures were characterized extensively by 1D and 2D NMR spectroscopy
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Dissertations / Theses on the topic "Monoterpene indole alkaloids"

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Jarret, Maxime. "Synthèses totales d’alcaloïdes indolo-monoterpéniques : (–)-17-nor-excelsinidine, (+)-16-épi-pléiocarpamine, (+)-16-hydroxyméthyl-pléiocarpamine et (+)-taberdivarine H." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS527.

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La pléiocarpamine est un alcaloïde indolo-monoterpénique de la famille des mavacurans. L’intérêt de cette substance naturelle réside dans sa capacité d’assemblage avec divers alcaloïdes indoliques donnant lieu à des bisindoles de structures complexes possédant des activités biologiques significatives. Plusieurs stratégies ont été étudiées pour la synthèse totale de ce composé pentacyclique. Notamment, la contraction d’un cétolactame a été envisagée pour la formation du cycle E. De manière inattendue, cette stratégie a conduit à la première synthèse totale de la (–)-17-nor-excelsinisine, un alc
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Matsuura, Hélio Nitta. "Papel do alcalóide N,B-D-glicopiranosil vincosamida na resposta a dano mecânico e herbivoria em Psychotria leiocarpa CHAM & SCHLTDL." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/143359.

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Metabólitos secundários são produzidos por alguns grupos vegetais e são essenciais nas diferentes estratégias de adaptação às adversidades ambientais, atuando na proteção e comunicação das plantas, sendo responsivos a diversos fatores bióticos e abióticos. Entre as diversas categorias de metabólitos secundários, os alcalóides apresentam principal função relacionada à defesa contra herbívoros; atuam também na proteção contra patógenos e na interação química com outras plantas (alelopatia). Alcalóides monoterpenos indólicos (MIAs) são uma classe de alcalóides de origem biossintética mista, e apr
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Otogo, n'nang Elvis. "Étude chimique et biologique de Gentianales gabonaises d’intérêt antipaludique, à alcaloïdes indolomonoterpéniques." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS039/document.

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L’étude chimique de 11 plantes du Gabon, dont certaines utilisées en médecine traditionnelle, a été réalisée à la recherche de composés antiplasmodiaux de structures nouvelles. Deux Apocynaceae (Pleiocarpa mutica Benth., Callichilia inaequalis Stapf) et une Gelsemiaceae (Mostuea brunonis Didr.) ont été plus spécifiquement étudiées, via une stratégie de déréplication fondée sur des réseaux moléculaires générés à partir de données CLHP-MS/MS (Molecular Networking) et annotés avec une base de données d’alcaloïdes indolomonoterpéniques mise au point au laboratoire (MIADB). Cette investigation a gu
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Szwarc, Sarah. "Développements méthodologiques en chimie analytique pour l'identification des enzymes catalysant des cyclisations C-N chez les alcaloïdes indolomonoterpéniques." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASQ074.

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Les alcaloïdes indolomonoterpéniques (AIM) constituent l'une des classes de produits naturels végétaux les plus diversifiées dans le vivant. Ces dernières années, l'étude de leurs voies de biosynthèse a suscité un intérêt croissant au sein de la communauté scientifique, notamment en raison des activités biologiques remarquables de certains de leurs représentants. Les avancées réalisées dans le domaine du génie métabolique permettent aujourd'hui de reconstituer les voies de biosynthèse de composés d'intérêt dans des organismes hôtes, contournant ainsi les limites des méthodes classiques d'obten
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Fox, ramos Alexander. "Exploration de la diversité chimique des Apocynaceae par la technique des réseaux moléculaires : de la création d’une base de données vers l’annotation in silico." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS543/document.

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Les alcaloïdes indolo-monoterpéniques (AIMs) constituent une classe de molécules naturelles très étudiée en raison d’un fort potentiel pharmacologique et thérapeutique et d’une grande diversité structurale. D’autre part, les techniques de déréplication par chromatographie liquide couplée à la spectrométrie de masse tandem ont évolué récemment, avec l’émergence de l’approche par réseaux moléculaires (molecular networking). Dans ce contexte, nous avons créé une base de données de spectres de masse tandem moyennés de 172 AIMs témoins, en collaboration avec plusieurs équipes de pharmacognosie dans
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Fragoso, Variluska. "Alcalóides de Psychotria : fotorregulação e propriedades antioxidantes e antimutagênicas." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/10958.

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Espécies de Psychotria encontradas no sul do Brasil produzem alcalóides do tipo monoterpeno indólicos, alguns deles com interessantes atividades biológicas e oriundos de novas rotas biossintéticas. P. leiocarpa Cham. & Schlecht. acumula N, b-D-glicopiranosilvincosamida (GPV), o primeiro alcalóide N-glicosilado desta classe a ser descrito. O extrato contendo GPV apresenta atividade analgésica inespecífica e, na planta, sua biossíntese é regulada pelo desenvolvimento e por luz. P. umbellata Vell., por sua vez, produz psicolatina, que apresenta alto potencial farmacológico, pois apresenta ativida
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Giddings, Lesley-Ann. "Discovery, characterization, and rational design of the enzymes involved in monoterpene indole alkaloid biosynthesis in Madagascar periwinkle." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65266.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, February 2011.<br>"February 2011." Vita. Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>The chemical diversity found in plants has served as a major source of inspiration to many synthetic and biological chemists. Nature has evolved enzyme active sites to catalyze the synthesis of structurally complex compounds that serve as pharmaceuticals, insecticides, dyes, perfumes, and biofuels. In Catharanthus roseus, approximately 130 structurally complex monoterpene indole alkaloids are produc
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Chebbi, Mouadh. "Implication de facteurs de transcription de type doigt de zinc et de la famille des WRKY dans la régulation de la voie du MEP et de la biosynthèse des alcaloïdes indoliques monoterpéniques de Catharanthus roseus." Thesis, Tours, 2015. http://www.theses.fr/2015TOUR3801/document.

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Les alcaloïdes indoliques monoterpéniques (AIM) sont des molécules à propriétés anti-tumorales extraites de Catharanthus roseus. Leur coût de production et les besoins encore importants de ces médicaments en chimiothérapie, en font des cibles majeures pour la recherche de stratégies de production plus efficaces. L’objectif de ce travail vise à identifier de nouveaux facteurs de transcription (FT) régulateurs de la production des AIM. Cette étude porte plus particulièrement sur la caractérisation fonctionnelle et l’implication dans la régulation de la biosynthèse des AIM, de protéines de la fam
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Ginis, Olivia. "Identification de facteurs de transcription régulateurs de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques chez Catharanthus roseus." Thesis, Tours, 2012. http://www.theses.fr/2012TOUR4014/document.

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Catharanthus roseus est une plante tropicale qui produit spécifiquement des alcaloïdes indoliques monoterpéniques (AIM) d’intérêt thérapeutique. Chez C. roseus, la branche terpénique incluant la voie du méthylérythritol phosphate (MEP) est considérée comme limitante et présente une régulation transcriptionnelle coordonnée en réponse aux hormones inductrices de l’accumulation alcaloïdique. Lors de ce travail, suite à des analyses bioinformatiques et à la caractérisation de promoteurs de gènes de la voie MEP, nous avons identifié de nouvelles familles de facteurs de transcription impliquées dans
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Magedans, Yve Verônica da Silva. "Metabolismo do alcaloide antioxidante braquicerina de Psychotria brachyceras Müll. Arg. sob estresse de calor." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/170190.

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O estresse de calor prejudica o crescimento e reprodução dos organismos vegetais, ao alterar a permeabilidade de membranas biológicas e desnaturar proteínas, limitando o metabolismo primário. Dentre as respostas ao estresse abiótico, está a síntese de metabólitos secundários. Braquicerina é um alcaloide monoterpeno indólico com ação antioxidante, protetora contra UV e antimutagênica sintetizado por partes aéreas de Psychotria brachyceras. O objetivo deste trabalho é investigar o metabolismo de braquicerina sob estresse de calor. Assim, espera-se contribuir para o conhecimento acerca do metabol
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Books on the topic "Monoterpene indole alkaloids"

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1927-, Saxton J. Edwin, ed. Monoterpenoid indole alkaloids. Wiley, 1994.

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Book chapters on the topic "Monoterpene indole alkaloids"

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Kurz, Wolfgang G. W., Friedrich Constabel, and Robert T. Tyler. "Biosynthesis of Monoterpene Indole Alkaloids in vitro." In Plant Tissue Culture Manual. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0303-9_3.

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Kurz, Wolfgang G. W., Friedrich Constabel, and Robert T. Tyler. "Biosynthesis of Monoterpene Indole Alkaloids in vitro." In Plant Tissue Culture Manual. Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0103-2_53.

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Le Pogam, Pierre, Erwan Poupon, Pierre Champy, and Mehdi A. Beniddir. "Implementation of an MS/MS Spectral Library for Monoterpene Indole Alkaloids." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2349-7_7.

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Akhtar, Shabnam, Javed Ahmad, and Altaf Ahmad. "Molecular Network of Monoterpene Indole Alkaloids (MIAs) Signaling in Plants with Reference to Catharanthus roseus (L.) G. Don." In Stress Signaling in Plants: Genomics and Proteomics Perspective, Volume 2. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-42183-4_2.

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Nakabayashi, Ryo. "Sample Preparation, Data Acquisition, and Data Analysis for 15N-Labeled and Nonlabeled Monoterpene Indole Alkaloids in Catharanthus roseus." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2349-7_4.

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Mehrotra, Shakti, Sonal Mishra, and Vikas Srivastava. "Hairy Root Cultures for Monoterpene Indole Alkaloid Pathway: Investigation and Biotechnological Production." In Hairy Roots. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2562-5_5.

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Amor Stander, Emily, Thomas Dugé de Bernonville, and Vincent Courdavault. "RNA-seq Analysis of Monoterpene Indole Alkaloid Biosynthetic Pathway Elucidation in Catharanthus roseus." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2349-7_9.

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Dugé de Bernonville, Thomas, Emily Amor Stander, Géraud Dugé de Bernonville, Sébastien Besseau, and Vincent Courdavault. "Predicting Monoterpene Indole Alkaloid-Related Genes from Expression Data with Artificial Neural Networks." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2349-7_10.

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Vázquez-Flota, Felipe A., María de Lourdesa Miranda-Ham, Julián Coello-Coello, and Víctor M. Loyola-Vargas. "Strategies for the Optimization of Culture Conditions for Increasing Metabolite Production Through Hairy Root Cultures: Monoterpene Indole Alkaloid Production in Catharanthus roseus Hairy Roots." In Hairy Root Cultures Based Applications. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-4055-4_6.

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DeLuca, Vincenzo, and Wolfgang G. W. Kurz. "Monoterpene Indole Alkaloids (Catharanthus Alkaloids)." In Phytochemicals in Plant Cell Cultures. Elsevier, 1988. http://dx.doi.org/10.1016/b978-0-12-715005-5.50029-7.

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Conference papers on the topic "Monoterpene indole alkaloids"

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Beniddir, MA. "Digitizing historical collections of natural products to further explore the monoterpene indole alkaloids chemical space." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3399672.

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