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Dissertations / Theses on the topic 'Monotremes'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lee, Mi-Hye. "Molecular biology and evolution of [beta]-globin genes in monotremes /." Title page, table of contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09phl479.pdf.

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2

Wong, Emily (Emily Sau Wai). "Characterisation of the marsupial and monotreme immunomes." Thesis, The University of Sydney, 2010. https://hdl.handle.net/2123/28962.

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In this thesis I utilize the recently sequenced genomes of the South American grey short-tailed opossum (Monodelphis domestica), tammar wallaby (Macropus eugeniz') and the platypus (Ornithorhynchus anatinus) to identify and characterize immune genes in order to fill in the gaps in our understanding of evolution of the immune systems in non-eutherian mammals. Many of these genes have proved elusive to identify using conventional lab strategies and automated genome annotation pipelines. I discovered divergent immune genes using bioinformatic protocols that I developed and compiled this seq

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3

Musser, Anne Marie School of Biological Earth &amp Environmental Sciences UNSW. "Investigations into the evolution of Australian mammals with a focus on monotremata." Awarded by:University of New South Wales. School of Biological, Earth and Environmental Sciences, 2005. http://handle.unsw.edu.au/1959.4/25739.

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This thesis began as an investigation into evolution of the platypus family (Ornithorhynchidae, Monotremata), now known from both Australia and South America. The thesis broadened its scope with inclusion of non-ornithorhynchid Mesozoic monotremes from Lightning Ridge, NSW. This change in direction brought an unexpected result: a fossil mammal from Lightning Ridge investigated for this thesis (presumed to be monotreme: Flannery et al., 1995) appears to be a new and unique type of mammal. Specimens were procured through Queensland Museum (Riversleigh material); Australian Museum (Lightning Ridg

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4

Hore, Timothy Alexander, and timothy hore@anu edu au. "THE EVOLUTION OF GENOMIC IMPRINTING AND X CHROMOSOME INACTIVATION IN MAMMALS." The Australian National University. Research School of Biological Sciences, 2008. http://thesis.anu.edu.au./public/adt-ANU20081216.152553.

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Genomic imprinting is responsible for monoallelic gene expression that depends on the sex of the parent from which the alleles (one active, one silent) were inherited. X-chromosome inactivation is also a form of monoallelic gene expression. One of the two X chromosomes is transcriptionally silenced in the somatic cells of females, effectively equalising gene dosage with males who have only one X chromosome that is not complemented by a gene poor Y chromosome. X chromosome inactivation is random in eutherian mammals, but imprinted in marsupials, and in the extraembryonic membranes of some place

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5

Peel, Emma Jane. "Peptides from the Pouch: Marsupial and Monotreme Cathelicidins." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/17934.

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The rise in antimicrobial resistance and paucity of new antimicrobial compounds calls for alternatives to traditional antibiotics. Antimicrobial peptides (AMPs) have emerged as potential candidates. Cathelicidins are a major family of AMPs in mammals which form part of innate immunity through antimicrobial and immunomodulatory functions. Marsupial and monotreme cathelicidins are of particular interest due to their involvement in protecting immunologically naive young during development in the pouch via expression in the pouch lining and milk where they modulate microbial flora and provide pass

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6

Haynes, Julie Irene. "Parathyroid glands in marsupials and monotremes / y Julie Irene Haynes." 1997. http://hdl.handle.net/2440/19161.

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Addendum pasted onto front end-paper.<br>Bibliography: leaves 214-226.<br>v, 227, [7] leaves, [71] leaves of plates : ill. (some col.) ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.A)--University of Adelaide, Dept. of Anatomical Sciences, 1998?

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7

Lee, Mi-Hye. "Molecular biology and evolution of beta-globin genes in monotremes / Mi-Hye Lee." Thesis, 1997. http://hdl.handle.net/2440/19126.

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Erratum pasted on front fly-leaf.<br>Bibliography: leaves 180-202.<br>xvii, 220 leaves : ill. (some col.) ; 30 cm.<br>The evolutionary relationships of the beta-like globin genes were studied by applying maximum parsimony methods to aligned DNA sequences.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Genetics, 1998?

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8

Toledo-Flores, Deborah Fernanda. "Evolution of mammalian sex chromosomes and sex determination genes: insights from monotremes." Thesis, 2015. http://hdl.handle.net/2440/97382.

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Genetic sex determination systems are generally based on the presence of differentiated sex chromosomes. Birds have a ZZ/ZW sex chromosome system in which males are ZZ and females ZW, whereas mammals have an XX/XY system with males being XY and females XX. Monotremes have an extraordinary sex chromosome system that consists of multiple sex chromosomes: 5X5Y in platypus and 5X4Y in echidna. Intriguingly, the monotreme sex chromosomes show extensive homology to the bird ZW and not to the therian XY. However, sex determination in monotremes is still a mystery; the Y-specific Sry gene that trigger

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9

Wallis, Mary C. "Evolution of mammal sex and sex chromosomes : the contribution of monotreme cytogenetics." Phd thesis, 2008. http://hdl.handle.net/1885/150937.

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10

Wright, Megan Lynne. "Investigating the evolution of replication timing and monoallelic expression in mammals and birds." Thesis, 2015. http://hdl.handle.net/2440/102613.

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Monoallelic expression and replication timing are closely linked fundamental aspects of genome biology, yet their evolutionary trajectory has not been investigated in much detail. The monoallelic expression status of imprinted genes observed in therian species has previously not been found in the earlier-diverged monotreme mammals, or in birds, when measured using molecular techniques. Furthermore, the observation that eutherian imprinted and X-borne genes asynchronously replicate was traditionally thought to be linked to the dissimilar epigenetic states that existed at each allele controlling

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11

Hore, Tim. "The Evolution of Genomic Imprinting and X Chromosome Inactivation in Mammals." Phd thesis, 2008. http://hdl.handle.net/1885/49309.

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Genomic imprinting is responsible for monoallelic gene expression that depends on the sex of the parent from which the alleles (one active, one silent) were inherited. X-chromosome inactivation is also a form of monoallelic gene expression. One of the two X chromosomes is transcriptionally silenced in the somatic cells of females, effectively equalising gene dosage with males who have only one X chromosome that is not complemented by a gene poor Y chromosome. X chromosome inactivation is random in eutherian mammals, but imprinted in marsupials, and in the extraembryonic membranes of some place

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12

He, Chuan. "Investigating function and evolution of genes and proteins involved in metabolic control in mammals." Thesis, 2015. http://hdl.handle.net/2440/104813.

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The duck-billed platypus and the short-beaked echidna represent the most basal lineage of living mammals and therefore provide important information about mammalian evolution. Monotremes have also undergone remarkable anatomical, physiological and genetic changes. One of the most radical changes involves the monotreme digestive system and genes associated with metabolic control. I have investigated several genes that are vital for metabolic control (specifically genes in the ghrelin and incretin pathways) as well as the histology of the monotreme pancreas. Given the glandless gut in monotremes

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13

Teahan, Carmel G. "Monotreme whey proteins: isolation, characterization and comparative aspects." Phd thesis, 1986. http://hdl.handle.net/1885/134058.

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Lactation is a specific mammalian adaptation. Milk is the principal source of nutrition for the newborn mammal. Both its needs and the physiology of lactation vary among the different mammalian species. These factors are reflected in the differing milk compositions, in particular the protein compositions. Thus, comparative studies of the protein composition of eutherian, metatherian and prototherian mammals are of great importance in their own right. Furthermore, these proteins exhibit an extraordinary array of conformations and protein-protein interactions. Thus, their study will also t

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14

Perri, Gavin. "The ecomorphology of the Monotreme cranium and the biogeography of Australia and New Guinea." Phd thesis, 2019. http://hdl.handle.net/1885/164323.

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Extant Monotremata is an egg-laying mammal Order only found in Australia and New Guinea and is comprised of the genera, Ornithorhynchus, Tachyglossus and Zaglossus. Monotremes have been observed to have a large amount of variation as seen in the number of subspecies and species that were previously recognised for the taxa. This thesis studied the factors that may be responsible for this amount of variation. The thesis was broadly divided into five factors hypothesised to affect the variation of the crania; growth and development, sex differences, climate, phylogeny, and other macroecological a

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15

Morrow, GE. "Optimizing reproduction in the Tasmanian echidna Tachyglossus aculeatus setosus: the influence of an obligatory hibernation period and intense sexual conflict." Thesis, 2013. https://eprints.utas.edu.au/17555/1/Front-Morrow-_thesis.pdf.

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The echidna is a solitary, seasonally breeding monotreme mammal with a mating system characterized by high levels of intra-male competition for access to receptive females. Throughout Australia the breeding season follows a period of inactivity which ranges from shallow bouts of torpor to prolonged deep hibernation. In this thesis I investigated how the Tasmanian echidna optimizes its reproduction around an obligatory hibernation period and in the presence of intense sexual conflict. The bradymetabolic (slowing of metabolism) effect of hibernation was exploited by both sexes to optimize their

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16

Latimer, Ashley Emilie. "Redescription of teeth and epithelial plates from the platypus (Ornithorhynchus anatinus) : morphological and evolutionary implications." Thesis, 2014. http://hdl.handle.net/2152/25675.

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The evolutionary history of mammals, when including extinct taxa, is mainly reconstructed using tooth morphology and employs terminology based on non-monotreme mammals. Although adult monotremes are edentulous, juvenile platypuses have teeth that can be compared with extinct monotremes, but terminology can be a barrier to efficient comparison to non-monotreme mammals. Deciduous teeth and thickened epithelial plates of the extant platypus, Ornithorhynchus anatinus, are sparsely figured in the literature. New imagery of those teeth and plates from high-resolution x-ray computed tomography and sc

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17

Harris, R. "Chemical communication for reproduction in the Tasmanian short-beaked echidna, Tachyglossus aculeatus setosus." Thesis, 2014. https://eprints.utas.edu.au/18649/3/Whole-Harris-thesis-inc-pub-mat.pdf.

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Communication plays a key role in coordinating all social interactions in an individual’s life, but is particularly crucial for coordinating reproduction. Although chemical (olfactory) signals are ubiquitous in sexual communication in mammals, a disproportionate reliance on laboratory-based studies using a limited range of species, along with several logistical and methodological limitations, limit our broader understanding of their functions in reproduction and as sexually selected traits. I addressed these shortcomings by using an integrated, multidisciplinary approach, combining organic che

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18

Casey, Aaron Edward. "Investigating the organisation of the platypus sex chromosome chain during meiotic prophase I." Thesis, 2015. http://hdl.handle.net/2440/96834.

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Meiosis is a specialised form of cell division that occurs specifically in the gonads of sexually reproducing species. It comprises a round of DNA replication followed by two successive rounds of cell division to produce haploid gametes. Each stage is divided into four substages of prophase, metaphase, anaphase and telophase. Prophase I is the longest and most complex stage of meiosis during which homologous chromosomes pair and recombine. The evolution of heteromorphic sex chromosomes has led to a number of changes in meiotic organisation. This includes the non-pairing of sex specific parts o

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19

O'Rielly, Rebecca Jane. "Dietary, Lifestyle and Pharmaceutical Interventions for the Treatment of Metabolic Diseases." Thesis, 2021. https://hdl.handle.net/2440/134327.

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The global prevalence of obesity and type 2 diabetes increases and current treatment options are not satisfactory. This thesis will investigate the efficacy of novel dietary, lifestyle, and pharmaceutical interventions to treat these metabolic disorders. In rodents, acute-isoleucine treatment lowers blood glucose levels and protects from diet-induced weight gain, suggesting chronic-isoleucine may be beneficial in treating obesity and type 2 diabetes. This study aimed to investigate chronic-isoleucine treatment on body weight and glucose tolerance in lean and obese mice. Male C57BL/6 mice, fed

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