Relevant bibliographies by topics / MoRF

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'MoRF'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 March 2023

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Journal articles on the topic "MoRF"

1

Katsumoto, Takuo, and Issay Kitabayashi. "Roles of Histone Acetyltransferase MORF and MOZ in Hematopoiesis." Blood 114, no. 22 (November 20, 2009): 2525. http://dx.doi.org/10.1182/blood.v114.22.2525.2525.

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Abstract Abstract 2525 Poster Board II-502 MOZ (MOnocytic leukemia Zinc finger protein) and MORF (MOz Related Factor), Myst-type histone acetyltransferases, are involved in chromosome translocations associated with FAB-M4/5 subtypes of acute myeloid leukemia. We have reported that MOZ is essential for hematopoietic cell development and self-renewal of hematopoietic stem cells. To explore the possibility MORF also plays important roles in hematopoiesis, we generated Morf-deficient mice with homologous recombination methods. Morf−/− mice were smaller than their wildtype littermates and died within 4 weeks after birth on C57BL/6 background. In MORF−/− fetal liver, Flt3-negative KSL (c-Kit+ Sca-1+ Lineage-) cells containing hematopoietic stem cells were decreased. When fetal liver cells were transplanted into irradiated recipient mice, MORF−/− cells less efficiently reconstituted hematopoiesis than wild-type cells. Additionally, bone marrow cells reconstituted with MORF−/− cells rarely contributed to hematopoiesis in secondary transplants. To reveal relationship between MORF and MOZ in hematopoiesis, we generated double heterozygous (Moz+/− Morf+/−) mouse. Double heterozygous mice were smaller than wild-type littermates and died at least 4 weeks after birth. Numbers of KSL cells, especially Flt3- KSL cells and common myeloid progenitors were decreased in the double heterozygous embryos. The double heterozygous fetal liver cells also displayed less activity to reconstitute hematopoiesis than MOZ+/− or MORF+/− cells. Since MORF−/− mice and MOZ/MORF double heterozygous mice were alive at adult on a mixed C57BL/6/DBA2 genetic background, we investigated adult hematopoiesis in these mice. MORF−/− or MOZ/MORF double heterozygous mice were smaller than their wild-type littermates and had small numbers of thymocytes and splenocytes. However, there were no significant differences in number of bone marrow cells and hematopoietic lineage population in MORF−/− or MOZ/MORF double heterozygous mice. These results suggest that MORF as well as MOZ plays important roles in self-renewal of hematopoietic stem cells. Disclosures: No relevant conflicts of interest to declare.
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Wang, Yi, Xinrong Liu, Kayoko Nakamura, Ling Chen, Mary Rusckowski, and Donald J. Hnatowich. "In Vivo Delivery of Antisense MORF Oligomer by MORF/Carrier Streptavidin Nanoparticles." Cancer Biotherapy and Radiopharmaceuticals 24, no. 5 (October 2009): 573–78. http://dx.doi.org/10.1089/cbr.2009.0624.

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Prihantoro, Prihantoro. "Current Implementation and Future Prospects of Santi-Morf V.1.0." Ranah: Jurnal Kajian Bahasa 10, no. 2 (December 27, 2021): 411. http://dx.doi.org/10.26499/rnh.v10i2.4189.

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SANTI-Morf (Prihantoro, 2021) is a new morphological analyser for Indonesian. In SANTI-Morf annotation scheme (Prihantoro, 2019), morpheme tokens are linked to their annotations. The tokens are presented in their orthographic and citation forms to allow (allo)morph or morpheme-based searches. Users can also perform retrievals on the basis of formal and functional morphological criteria as SANTI-Morf tagset encodes the analyses of morphemes’ forms (e.g. roots, clitics, affix type) and functions (e.g. passive voice, active voice, adjective degrees, etc.). Currently, the scheme is implemented in Nooj (Silberztein, 2003), a linguistic development environment. It enables users to index and annotate Indonesian texts in their local PC, and later perform searches based on morphological criteria and or tokens defined by the SANTI-Morf scheme. AbstrakSANTI-Morf (Prihantoro, 2021) adalah sebuah program analisis morfologi terbaru untuk bahasa Indonesia. Dalam skema anotasi SANTI-morf (Prihantoro, A new tagset for morphological analysis of Indonesian, 2019), setiap token morfem terhubung dengan anotasinya. Token-token ini direpresentasikan dalam bentuk ortografis dan bentuk sitasi sehingga memungkinkan pengguna untuk melakukan penelusuran berbasis (alo)morf atau morfem. Selain itu, pengguna juga bisa melakukan penelusuran berbasiskan bentuk atau fungsi morfem. Ini karena tagset analitik yang digunakan di SANTI-morf mencakup bentuk (di antaranya: akar, klitik, jenis afiksasi) dan fungsi (di antaranya: aktif, pasif, derajat ajektiva). Saat ini, SANTI-morf diimplementasikan menggunakan NooJ (Silberztein, 2003), sebuah program pengembangan aplikasi linguistik. Pengguna dapat mengindeks dan menganotasi teks berbahasa Indonesia di komputer mereka, dan selanjutnya melakukan penelusuran menggunakan kriteria morfologi dan skema tokenisasi yang digunakan di skema anotasi SANTI-morf.
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Xiong, Yuhong, Jing Fang, Xiaohan Jiang, Tengfei Wang, Kangchen Liu, Huixiang Peng, Xiujun Zhang, and Aidi Zhang. "Genome-Wide Analysis of Multiple Organellar RNA Editing Factor (MORF) Family in Kiwifruit (Actinidia chinensis) Reveals Its Roles in Chloroplast RNA Editing and Pathogens Stress." Plants 11, no. 2 (January 6, 2022): 146. http://dx.doi.org/10.3390/plants11020146.

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Kiwifruit (Actinidia chinensis) is well known for its high vitamin C content and good taste. Various diseases, especially bacterial canker, are a serious threat to the yield of kiwifruit. Multiple organellar RNA editing factor (MORF) genes are pivotal factors in the RNA editosome that mediates Cytosine-to-Uracil RNA editing, and they are also indispensable for the regulation of chloroplast development, plant growth, and response to stresses. Although the kiwifruit genome has been released, little is known about MORF genes in kiwifruit at the genome-wide level, especially those involved in the response to pathogens stress. In this study, we identified ten MORF genes in the kiwifruit genome. The genomic structures and chromosomal locations analysis indicated that all the MORF genes consisted of three conserved motifs, and they were distributed widely across the seven linkage groups and one contig of the kiwifruit genome. Based on the structural features of MORF proteins and the topology of the phylogenetic tree, the kiwifruit MORF gene family members were classified into six groups (Groups A–F). A synteny analysis indicated that two pairs of MORF genes were tandemly duplicated and five pairs of MORF genes were segmentally duplicated. Moreover, based on analysis of RNA-seq data from five tissues of kiwifruit, we found that both expressions of MORF genes and chloroplast RNA editing exhibited tissue-specific patterns. MORF2 and MORF9 were highly expressed in leaf and shoot, and may be responsible for chloroplast RNA editing, especially the ndhB genes. We also observed different MORF expression and chloroplast RNA editing profiles between resistant and susceptible kiwifruits after pathogen infection, indicating the roles of MORF genes in stress response by modulating the editing extend of mRNA. These results provide a solid foundation for further analyses of the functions and molecular evolution of MORF genes, in particular, for clarifying the resistance mechanisms in kiwifruits and breeding new cultivars with high resistance.
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Xia, Ting, Zhi-Yong Yu, and Han-Yuan Gong. "Pb2+-Containing Metal-Organic Rotaxane Frameworks (MORFs)." Molecules 26, no. 14 (July 13, 2021): 4241. http://dx.doi.org/10.3390/molecules26144241.

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The metal-organic rotaxane framework (MORF) structures with the advantage of mechanically interlocking molecules (MIMs) have attracted intense interest from the chemical community. In this study, a set of MORFs (i.e., MORF-Pb-1 and MORF-Pb-2) are constructed using Pb2+, a tetraimidazolium macrocycle (Texas-sized molecular box; 14+), and aromatic dicarboxylate (p-phthalate dianions (PTADAs; 2) or 2,6-naphthalene dicarboxylate dianions (3)) via a one-pot three-layer diffusion protocol. In particular, an unusual Pb…Pb weak interaction was shown in MORF-Pb-1 (charactered with distance of 3.656 Å).
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Ullah, Mukta, Nadine Pelletier, Lin Xiao, Song Ping Zhao, Kainan Wang, Cindy Degerny, Soroush Tahmasebi, et al. "Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes." Molecular and Cellular Biology 28, no. 22 (September 15, 2008): 6828–43. http://dx.doi.org/10.1128/mcb.01297-08.

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ABSTRACT The monocytic leukemia zinc finger protein MOZ and the related factor MORF form tetrameric complexes with ING5 (inhibitor of growth 5), EAF6 (Esa1-associated factor 6 ortholog), and the bromodomain-PHD finger protein BRPF1, -2, or -3. To gain new insights into the structure, function, and regulation of these complexes, we reconstituted them and performed various molecular analyses. We found that BRPF proteins bridge the association of MOZ and MORF with ING5 and EAF6. An N-terminal region of BRPF1 interacts with the acetyltransferases; the enhancer of polycomb (EPc) homology domain in the middle part binds to ING5 and EAF6. The association of BRPF1 with EAF6 is weak, but ING5 increases the affinity. These three proteins form a trimeric core that is conserved from Drosophila melanogaster to humans, although authentic orthologs of MOZ and MORF are absent in invertebrates. Deletion mapping studies revealed that the acetyltransferase domain of MOZ/MORF is sufficient for BRPF1 interaction. At the functional level, complex formation with BRPF1 and ING5 drastically stimulates the activity of the acetyltransferase domain in acetylation of nucleosomal histone H3 and free histones H3 and H4. An unstructured 18-residue region at the C-terminal end of the catalytic domain is required for BRPF1 interaction and may function as an “activation lid.” Furthermore, BRPF1 enhances the transcriptional potential of MOZ and a leukemic MOZ-TIF2 fusion protein. These findings thus indicate that BRPF proteins play a key role in assembling and activating MOZ/MORF acetyltransferase complexes.
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Benlamri, Rachid, and Luke Docksteader. "MORF: A Mobile Health-Monitoring Platform." IT Professional 12, no. 3 (May 2010): 18–25. http://dx.doi.org/10.1109/mitp.2010.3.

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Wong, J., D. Lee, M. Mangada, V. Yadav, D. Troast, C. Zhong, K. Hahn, et al. "DOP50 Oral α4β7 integrin inhibitor MORF-057 demonstrates exposure driven biomarker response in non-human primates." Journal of Crohn's and Colitis 16, Supplement_1 (January 1, 2022): i098—i099. http://dx.doi.org/10.1093/ecco-jcc/jjab232.089.

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Abstract Background Disruption of immune cell trafficking via integrins is a proven and effective mechanism for treating inflammatory bowel disease. When α4β7 integrin is inhibited through pharmacological intervention, immune cells destined for the gut tissue become sequestered in blood circulation and these alterations can be detected through several methods. MORF-057 is a novel, oral, selective, small molecule inhibitor of α4β7 integrin developed for treating IBD. MORF-057 demonstrated favorable tolerability, pharmacokinetic and pharmacodynamic profiles including saturating receptor occupancy and corresponding evidence for proof of biology based on effects on circulating cells during a Phase 1 clinical trial in healthy volunteers (Ray, ECCO 2021). Here we demonstrate an exposure:response relationship of α4β7 related biomarkers examined among MORF-057 treated non-human primates (NHPs) as a means for pre-clinical testing of inhibitors of this pathway. Methods Single-cell RNA sequencing (scRNAseq) was performed on NHP CD45+ blood cells to determine baseline populations potentially impacted through exposure to MORF-057. 40 Naïve cynomolgus monkeys were enrolled over 5 separate studies and dosed orally BID with MORF-057 over 2–7 days using several dose levels to examine biomarker dynamics over a wide range of exposures. Peripheral blood was sampled at various timepoints (n= 125) and assayed using: mass spectroscopy, flow cytometry (FACS), and mRNA quantification to determine MORF-057 exposure levels, on-target receptor occupancy (RO), immune cell subset changes, and CCR9 mRNA levels. Results MORF-057 Ctrough ranged from 3.3–429 ng/ml. In samples tested for RO, MORF-057 achieved >95% saturation of α4β7 even with the lowest Ctrough of 4.5 ng/ml. MORF-057 treatment led to significantly sustained increases in circulating β7high CD4+ T memory cells detectable as early as 24h post-exposure. A maximal effect where β7high cells accounted for approximately 60% of the T memory population was achieved at saturating receptor occupancy (Fig., left). CCR9 mRNA values demonstrated increases upon drug exposure (Fig., right). Conclusion In NHP, acute changes in circulating β7high T memory cells was a sensitive biomarker demonstrating a dose-dependent response to MORF-057 exposure. CCR9 mRNA levels also showed similar exposure related changes reflecting its expression on a subset of β7high cell types. Analysis of scRNAseq shows expression of α4β7 on other cell types beyond T memory cells including: NK, NKT, B cells, plasmablasts, monocytes, and eosinophils. Pharmacodynamic changes in NHP are consistent with human Phase 1 data in healthy volunteers.
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Jones, J., D. Lee, I. Smukste, D. Cui, M. G. Bursavich, D. Troast, C. Zhong, et al. "P037 Nonclinical pharmacokinetics and absorption, distribution, metabolism, and excretion properties of MORF-057 support its clinical development as an oral selective α4β7 integrin inhibitor." Journal of Crohn's and Colitis 15, Supplement_1 (May 1, 2021): S149—S150. http://dx.doi.org/10.1093/ecco-jcc/jjab076.166.

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Abstract Background MORF-057 is a potent and selective small molecule inhibitor of the α 4β 7 integrin. Using a receptor occupancy (RO) assay under physiologically relevant conditions, MORF-057 achieves 90% α 4β 7 RO at approximately 10 nM in human whole blood. The current studies evaluate nonclinical pharmacokinetics (PK) and properties of absorption, distribution, metabolism, and excretion (ADME) to enable dose/exposure projection to humans. Methods PK studies were conducted in mouse, rat, dog, and monkey following intravenous (IV) and oral administration. ADME studies were conducted in vitro and in rats using carbon-14 [14C] labeled MORF-057. MORF-057 levels were quantified using liquid chromatography coupled with tandem mass spectrometry. Human PK was predicted based on body weight allometry, well-stirred and semi-physiological models. Results MORF-057 exhibited low to moderate clearance (CL) in animals with species dependent volume of distribution (Vdss) resulting in half-lives of 1.1 to 2.7 hours (Table 1). Following an oral dose, absorption was high with bioavailability ranging from 15% to 49%. MORF-057 is highly protein bound and distribution of [14C]MORF-057 derived radioactivity in rat was predominantly in the small intestine wall, liver, and stomach wall. Rifampin, an inhibitor of organic anion transporting polypeptides, decreased MORF-057 clearance by 3-fold in monkeys suggesting MORF-057 elimination involves hepatic uptake transport. MORF-057 is further cleared via CYP3A metabolism followed by biliary/fecal elimination of metabolites. MORF-057 is predicted to have moderate bioavailability (40%) and CL (6.5 mL/min/kg) in humans. Wajima transformation shows good agreement of the normalized PK across animal species, with a predicted human concentration-time profile supporting >90% α 4β 7 RO at trough following 200 mg twice daily dose (Figure 1). Conclusion These data demonstrate that MORF-057 is well absorbed and PK properties in animals support the potential for achieving high α4β7 RO following oral administration in humans. These nonclinical results provided a basis for the progression of MORF-057 into a first-in-human Phase 1 clinical study assessing safety, pharmacokinetics, and receptor occupancy (results being reported separately).
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Yochum, Gregory S., and Donald E. Ayer. "Role for the Mortality Factors MORF4, MRGX, and MRG15 in Transcriptional Repression via Associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split." Molecular and Cellular Biology 22, no. 22 (November 15, 2002): 7868–76. http://dx.doi.org/10.1128/mcb.22.22.7868-7876.2002.

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ABSTRACT mSin3A and Transducin-Like Enhancer of Split (TLE) are two histone deacetylase (HDAC)-containing corepressors that function to repress transcription at targeted genes. Pf1 is a plant homeodomain zinc finger protein that interacts with both mSin3A and TLE, suggesting that it coordinates their function. Here we show that mSin3A and TLE interact with members of the mortality factor (MORF) family of putative transcriptional regulators. This family comprises MORF on chromosome 4 (MORF4) and MORF-related genes on chromosomes X and 15 (MRGX and MRG15, respectively) and is proposed to contribute to cellular senescence. Consistent with a role in transcription, we demonstrate that Gal4 fusions to each MORF family member repress transcription from a Gal4-dependent luciferase reporter. By using both mapping experiments and a dominant negative form of TLE, we show that repression by MORFs requires associations with mSin3A and TLE. Therefore, common functions of the MORFs are likely elicited through the action of a MORF/mSin3A/TLE complex. While the MORFs may have common functions, MRG15, but not MRGX or MORF4, interacted with Pf1. Therefore, MRG15 may have functions that are distinct from those of MRGX and MORF4. Consistent with this hypothesis, Pf1 reduced transcriptional repression by Gal4-MRG15 but it had no effect on repression by MRGX and MORF4. Pf1 has independent binding sites for MRG15 and mSin3A. In addition, Pf1 and MRG15 bind different domains on mSin3A. Together, these data suggest that the unique functions of MRG15 are elicited through the action of an MRG15/Pf1/mSin3A complex.
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Dissertations / Theses on the topic "MoRF"

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Pelletier, Nadine. "The monocytic Leukemia zinc finger protein MOZ and its related factor MORF /." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84309.

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Regulation of chromatin structure involves histone modifications such as acetylation. Since 1996, the identification and characterization of histone acetyltransferases have had tremendous impact on our understanding of the molecular mechanisms related to eukaryotic gene regulation and human diseases associated with abnormal chromatin functions. The MYST family of histone acetyltransferases is very interesting because of their various biological functions. In agreement with the correlation between aberrant histone acetylation and cancer, the MYST family proteins MOZ and MORF are linked to leukemogenesis.
Identification and characterization of a gene encoding a novel histone acetyltransferase were the goals of this thesis project. Human MORF gene was cloned and the encoded protein, MORF, was shown to be very similar to MOZ. Biochemical studies demonstrated that both MOZ and MORF possess intrinsic histone acetyltransferase activities. The amino- and carboxy-terminal regions of MOZ and MORF contain transcriptional repression and activation domains, respectively.
Runx2, an osteoblast-specific transcription factor, binds to the activation domains of MOZ and MORF and thus recruits them to the osteocalcin promoter for transcriptional activation. TAZ, a WW-domain transcriptional coactivator of Runx2, potentiates the transcriptional activation of the osteocalcin promoter by MOZ and Runx2. Interestingly, treatment of cells with PMA enhances the synergy between MOZ and TAZ in activating the osteocalcin promoter. Consistent with this, PMA treatment strengthens the interaction of Runx2 with MOZ and TAZ.
This study, therefore, identified the histone acetyltransferase MORF and demonstrated that MOZ and MORF are transcriptional coactivators, thus providing new insights into how histone acetyltransferases are implicated in cell differentiation and leukemogenesis.
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Glass, Franziska [Verfasser]. "Analyse der Funktion von MORF-Proteinen im mitochondrialen RNA-Editing in Arabidopsis thaliana / Franziska Glass." Ulm : Universität Ulm, 2017. http://d-nb.info/1137557680/34.

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Pires, Caroline de Castro. "Ep?ntese consonantal em contexto de juntura morf?mica : considera??es sobre o sufixo -ada." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2016. http://tede2.pucrs.br/tede2/handle/tede/6724.

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This study is a morphophonological and etymology analysis of words from a dictionary (HOUAISS, 2009) with the termination -ada, more specifically, we observe the morphemic context (base + suffix) of word derived from nominal basis, with and without consonant insertion and we try to find generalizations. It should be noted, especially, that this dissertation is meant to discuss words with nominal bases that have consonantal epenthesis ? a mechanism used to solve structural problems of syllabic character. For data analysis, methodologically, the sample was divided into three major groups: (i) words derived from nominal basis (divided into thematic and athematic words); (Ii) words derived from verbal basis; and (iii) words with the termination -ada not suffixal (composed of vernacular formations and loans). From this work, it was found that words derived from thematic and athematic bases (it refers to a regular insertion in Portuguese) behave differently: (i) words with athematic bases, insert /z/, consonant less invasive, because only solves the syllabic character problem (cf. p? + -ada > pazada); (ii) words with thematic bases insert /r/ and neutralize the VT of base word in favor of the vowel /a/ (cf. bicho + -ada > bicharada). Moreover, the consonant epenthesis were characterized on the basis of texts used as theoretical foundation and the analysis of data which allowed the identification of more favorable context for the consonant inserts in PB: the athematic base words (20.5% against 2.6% of the thematic base words). Within of the athematic, the most favorable context is the words ending in a vowel candidate of accent (66.6%). Was highlighted also the possible reasons for the PB system select other consonants, different from /z/ and /r/, based on our data, like the fact there are already similar forms in the language with different semantics specification (cf. livroxada ~ livrada), the issue of variation (cf. bambu < bambucada ~ bambuzal ~ bambu?al), and cases of etymological trace (cf. paulada). Finally, we highlighted the need to carry out tests with speakers to observe the productivity of /z/ and /r/ in the PB system, the hypothesis is that /r/ is more crystallized in the language, and /z/ it is consonant with regular insertion force, i.e., probably it is the consonant more applied by native speakers of PB.
Este estudo constitui uma an?lise morfofonol?gica e etimol?gica de palavras dicionarizadas (HOUAISS, 2009) com a termina??o ?ada, mais especificamente, observamos o contexto de juntura morf?mica (base + sufixo) de palavras derivadas de base nominal, com e sem inser??o consonantal, em busca de generaliza??es. Cabe salientar, principalmente, que esta disserta??o tem por intuito discutir as palavras de base nominal que apresentam ep?ntese consonantal ? mecanismo utilizado para resolver problemas estruturais de car?ter sil?bico. Para a an?lise dos dados, metodologicamente, a amostra foi distribu?da em tr?s grandes grupos: (i) palavras derivadas de base nominal (divididas em tem?ticas e atem?ticas); (ii) palavras derivadas de base verbal; e (iii) palavras com a termina??o ?ada n?o sufixal (composta por forma??es vernaculares e empr?stimos). A partir disso, verificou-se que palavras derivadas de bases tem?ticas e atem?ticas (ao que se refere ? inser??o de consoante regular no portugu?s) se comportam de maneira diferente, em PB: (i) palavras de bases atem?ticas, na deriva??o, de modo geral, inserem /z/, consonante menos invasiva, que apenas resolve o problema de car?ter sil?bico (cf. p? + -ada > pazada); (ii) palavras de bases tem?ticas inserem /r/ e neutralizam a VT da base em favor da vogal /a/ (cf. bicho + -ada > bicharada). Al?m disso, as ep?nteses consonantais foram caracterizadas com base nos textos utilizados como fundamenta??o te?rica e na an?lise dos dados o que permitiu a identifica??o do contexto mais favor?vel para as inser??es consonantais, em PB: o grupo das palavras de base atem?tica (20,5%, contra 2,6% das palavras de base tem?tica). Dentro do grupo das atem?ticas, o contexto mais prop?cio ? o das palavras terminadas em vogal candidata a acento (66,6%). Foi destacado, ainda, os poss?veis motivos para o sistema do PB selecionar outras consoantes diferente de /z/ e /r/, com base em nossos dados, como o fato de j? haver outras formas semelhantes na l?ngua com diferente especifica??o sem?ntica (cf. livroxada ~ livrada), a quest?o da varia??o (cf. bambu < bambucada ~ bambuzal ~ bambu?al), e os casos de vest?gio etimol?gico (cf. paulada). Por fim, salientou-se a necessidade de se realizar testes com falantes para se observar a produtividade de /z/ e /r/ no sistema do PB. Nossa hip?tese ? de /r/ est? mais cristalizada na l?ngua, e que /z/ ? a consoante de inser??o regular vigente, isto ?, a consoante provavelmente mais aplicada por falantes do PB.
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Jahrehorn, Tea. "Mord, Mosse, Människor : Mors Ianua Vitae." Thesis, Linnéuniversitetet, Institutionen för kulturvetenskaper (KV), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-59787.

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What happened to the people in the bogs, and will we ever know why? This paper will try to answer this by studying cases from the bronze-to-Iron age in the North of Europe, by applying forensic, historic and criminological methods. In my paper I have conclu- ded that there is not a single motive to why the people in the bog were murdered. Ho- wever I have determined that they were all murdered.
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Barros, Silvana Diene Sousa. "Aspectos morfo-tect?nicos nos plat?s de Portalegre, Martins e Santana/RN." Universidade Federal do Rio Grande do Norte, 1998. http://repositorio.ufrn.br:8080/jspui/handle/123456789/18753.

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A morpho-structural analysis was performed in the uplifted siliciclastic deposits of the Serra do Martins Formation along the Portalegre, Martins and Santana plateaux, in the southeastern and central regions of Rio Grande do Norte State. Due to the lack of biostratigraphic records, this formation has a disputable age.The adopted approach was based on the analysis of the drainage patterns and in the recognition of topographic surfaces and regional structures, subjected to neotectonic deformation and rejuvenation the present stress field. These events are recorded in the lineament arrays and as anomalous features of the landscape, such as the uplifted plateaux.The morpho-sculptural evolution of the studied blocks is expressed as erosive and accumulative processes. The former ones include erosional scarpments, cuestas and amphitheaters as the most characteristic features, while debris slopes represent acumulative examples. Such elements attest to the recent disequilibrium of the plateaux, and the absence of well developed alluvium terraces suggest an accelerated uplift process. The directions of the linear features observed in remote sensing products evidence the control of the basement structural trends, inherited from the pre-Cenozoic evolution. The NNE-SSW direction controls the main erosional features of the plateaux, while the N-S direction is a major drainage control, being also recognized in the Potiguar Basin. An E-W trend occurs as a less developed direction, reflecting either a system of mesozoic basic dykes or precambrian brittle structures. As regards to the drainage arrays, an arborescent, varying to a roughly N-S rectangular pattern, was identified in the Portalegre-Martins block. The Santana plateau displays rectilinear (northern border) and dendritic arborescent (southern border) patterns. In the sedimentary cover, the drainage pattern varies from rectangular to angular, reflecting inheritance from the crystaline basement. The most significative directions, N, NE and NW, mark the erosional fronts of the plateaux. Drainage anomalies, characterized by elbows or paralell confluencies, reinforce the arguments mentioned above. The data sets evidence the relationships between endogenous (lithology, structures) and exogenous features as the main controls of terrain dissecation, associated to vertical (epirogenesis) movements and horizontal tectonics. A final discussion addresses the relationships of the Serra do Martins Formation with the sedimentary record of Potiguar Basin, trying to establish chronostratigraphic links with the main evolutionary steps of this part of the Borborema Province, and possible mechanisms involved in the uplift of the plateaux and other stratigraphic units in the region
A an?lise morfo-tect?nica aqui apresentada teve por objetivo estudar os dep?sitos silicicl?sticos soerguidos da Forma??o Serra do Martins, no contexto dos plat?s de Portalegre, Martins e Santana, situados nas por??es sudoeste e central do Estado do Rio Grande do Norte. A referida forma??o tem idade discut?vel, por n?o apresentar registros crono e/ou bioestratigr?ficos que a posicionem temporalmente. A sistem?tica de investiga??o adotada fundamentou-se na an?lise da rede de drenagem, no reconhecimento de superf?cies topogr?ficas e das estruturas regionais, submetidas a eventos e reativa??es neotect?nicas. Estes aspectos t?m reflexo direto no arranjo dos lineamentos e em fei??es an?malas identificadas na paisagem, p. ex., os plat?s soerguidos. A evolu??o morfo-escultural dos blocos estudados est? expressa atrav?s de processos erosivos e acumulativos. Dentre as fei??es dissecativas as escarpas de eros?o, cuestas e anfiteatros s?o as mais caracter?sticas, enquanto que os debris slopes constituem um exemplo acumulativo marcante. Estes elementos marcam o desequil?brio recente dos plat?s, onde a aus?ncia de expressivos terra?os aluvionares reflete um processo de r?pido soerguimento. As dire??es das fei??es lineares observadas nos produtos de sensoriamento remoto evidenciam o controle dos trends estruturais do embasamento, herdados da evolu??o pr?-Cenoz?ica. A orienta??o NNE-SSW controla fei??es erosionais dos plat?s, e o trend N-S condiciona o arranjo da drenagem, sendo tamb?m reconhecido na Bacia Potiguar. O trend E-W ocorre de forma menos intensa, refletindo o sistema de diques b?sicos mesoz?icos ou estruturas fr?geis precambrianas. No tocante ao arranjo da drenagem, o padr?o arborescente com varia??es para retangular com dire??o geral para norte foi identificado no bloco Portalegre-Martins. O plat? de Santana ordena-se em padr?es retil?neo (borda norte) e dendr?tico arborescente (sul). Na cobertura sedimentar o arranjo varia de retangular a angular, refletindo o arcabou?o herdado do embasamento cristalino. As dire??es mais significativas s?o N, NE e NW, marcando os trends erosivos. As anomalias de drenagem caracterizadas por deflex?es em cotovelo ou conflu?ncias em arranjo paralelo refor?am os argumentos acima expostos. Os estudos evidenciam a rela??o dos fatores end?genos (litologia, fei??es estruturais) em combina??o aos ex?genos, como condicionantes do maior ou menor grau de disseca??o do relevo, associados aos movimentos verticais (epirog?nese) e ? tect?nica horizontal. S?o discutidas as v?rias possibilidades de correla??o da Forma??o Serra do Martins com os sedimentos encontrados na Bacia Potiguar emersa, objetivando estabelecer poss?veis conex?es crono-estratigr?ficas com os v?rios epis?dios evolutivos desta por??o da Prov?ncia Borborema, e os prov?veis mecanismos envolvidos no soerguimento destes plat?s e de outras unidades estratigr?ficas regionais
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Baseotto, Paola. "'La mort ny mord' : aspects of death in Spenser's works." Thesis, University of Reading, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397775.

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Phélippeau, Marie-Claire. "La mort et le péché dans les écrits de Sir Thomas More." Paris 3, 2007. http://www.theses.fr/2007PA030105.

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Cette thèse étudie les rapports entre la mort et le péché dans les écrits de Sir Thomas More (1478–1535). L’un des objectifs est de rechercher les motivations spirituelles et non politiques qui ont pu pousser l’auteur à choisir délibérément le martyre, mais sans réduire sa vie aux mois qui ont précédé son exécution. Partant de l’évolution de la conception de la mort et du salut dans la pensée occidentale, l’analyse se propose de déterminer la position de Thomas More dans le discours pastoral de la chrétienté, et l’originalité de son propos par rapport à quelques autres humanistes du XVIe siècle, notamment dans l’élaboration des artes moriendi. Le péché, jugé mortifère suivant l’enseignement paulinien et augustinien, est étudié sous ses divers aspects dans les écrits moriens : péché originel et péché capital, péché mortel et péché véniel. Il est un sujet de polémique essentiel au moment de la lutte contre les luthériens, dans laquelle More se distingue tout particulièrement et qui fera évoluer sa position vers une plus grande rigidité. L’étude se poursuit par une exploration des représentations moriennes de l’au-delà : Jugement, enfer, diable et purgatoire. Une définition du paradis morien clôture une ultime partie consacrée à la sainteté et au martyre. La thèse avancée est que Thomas More a choisi le martyre pour être assuré de gagner le paradis, poussé par la crainte de la damnation peut-être, mais surtout mu par un exceptionnel désir du ciel perceptible dans l’ensemble de ses écrits
This study examines the relationship between death and sin in the writings of Sir Thomas More (1478-1535). It aims at better understanding the author and researching the spiritual motivations – independently of the political reasons – which may have driven him to deliberately choose martyrdom, but without reducing his life to its last months. Drawing from the evolution of the conception of death and salvation in Western thinking, the analysis endeavours to determine Thomas More’s position in Christian pastoral teaching, and to show the originality of his approach compared to that of a few other 16th century humanists, especially as regards ars moriendi. Since Paul, and then Augustine, established that sin brought death, the two concepts are analysed in relation to each other, and various aspects of sin are examined, such as original sin and capital sins, mortal and venial sins. In the fight against Lutheran ideas, the conception of sin is a polemical subject, and More, at the core of the debate, is led to harden his position on the matter. The study then explores the Morean representations of after-life : Judgement, Hell, the devil and Purgatory. A definition of the Morean paradise marks the end of the last part of this study, devoted to sainthood and martyrdom. The thesis developed here is that Thomas More chose martyrdom to be assured of a place in paradise, out of fear of damnation perhaps, but more likely, out of an exceptional longing for heaven, perceptible throughout his work
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Essid, Kaouthar. "Imageries de la mort et art contemporain." Thesis, Paris 1, 2013. http://www.theses.fr/2013PA010739.

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La mort est une réalité qui nous hante et qu'on s'obstine à occulter. Cette hantise de la mort peut-elle en faire un objet d'art ou l'objet d'un art qui tend à réévaluer le statut du corps humain à notre époque ? Il existe une opposition fondamentale entre le corps humain voué à la disparition et la conception contemporaine d'un corps beau et inaltérable. A travers ce memento mori, je traite la mort en tant qu'expression plastique et je soulève le questionnement de sa légitimité en tant que langage pictural. Ma confrontation avec la mort m'a amenée à réaliser des œuvres qui méditent sur l'existence, sur la temporalité et sur la nature du rapport de l'être humain à son corps et sur la mort dans ses diverses connotations
Death is a fact that persues us inspite of our efforts to dissimulate it. The question seems accordingly to be : can this obsession be turned into an object of art which tends to reconsider the status of the human body in our epoch ? There is an essential opposition between the human body that is doomed to vanish and the contemporary vision of a beautiful and unaltered body. Threoughout this "memento mori", I tried to explore death as a plastic expression which raises the question of its legitimacy as a pictorial language. My confrontation with death allowed me to achieve several works that meditate upon existence, temporality, and the nature of the relationship between the human being and his body, and death in its various connotations
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Olivera, Mendoza Luis Mauricio. "Doble invocación y venida de los Dioscuros : las transformaciones en las isotopías temáticas de la muerte, del amor y de la escritura en Amour á mort de César Moro." Master's thesis, Pontificia Universidad Católica del Perú, 2016. http://tesis.pucp.edu.pe/repositorio/handle/123456789/8026.

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La pregunta que formula la presente investigación gira en torno a las razones por las cuales César Moro escogió el mito de los Dioscuros para su poemario Amour à mort. En los párrafos que siguen se revisará las opiniones críticas de varios grupos de intelectuales que, a nuestro criterio, han aportado argumentos generales y específicos que proporcionan lucidez y debate en el camino hacia una de las posibles respuestas satisfactorias a la pregunta. En principio, los razonamientos críticos sobre la obra de Moro se remontan a los años en que el poeta logró publicar algunos poemarios en lengua francesa, continúan, con algunas intermitencias causadas por la escasa publicación de la obra del poeta, después de su fallecimiento, a lo largo de la segunda mitad del siglo veinte, y prosiguen de manera consolidada durante las primeras décadas del siglo en curso, gracias a la mayor cantidad de publicaciones de su obra, a partir de 1980, y la celebración del centenario de su nacimiento en el 2003. En el párrafo final incorporaremos nuestra hipótesis de trabajo acerca del núcleo intratextual sobre el cual reside la elección del mito de los Dioscuros.
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Lamminen, Hagerfors Siri. "More is More." Thesis, Konstfack, Grafisk Design & Illustration, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-5922.

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Books on the topic "MoRF"

1

Otter, Olphaert den. S&k morf. Rotterdam: Museum Boijmans Van Beuningen, 2008.

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Cneut, Carll. The amazing love story of Mr. Morf. New York: Clarion Books, 2002.

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Cneut, Carll. The amazing love story of Mr. Morf. New York, N.Y: Clarion Books, 2003.

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Boi︠a︡dzhiev, Todor. Sŭvremenen bŭlgarski ezik: Fonetika--leksikologii︠a︡--slovoobrazuvane--morf ologii︠a︡--sintaksis. Sofii︠a︡: Petŭr Beron, 1998.

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Frei, Annette. Die Welt ist mein Haus: Das Leben der Anny Klawa-Morf. Zürich: Limmat, 1991.

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Roger, Parisot, ed. La mort n'y mord. [Paris]: La Différence, 1996.

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1938-, McAdam Derek, ed. Qui a tué Diana? Genève: Timéli, 2006.

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Das Leuchten der Sirene: Ein Roman aus dem alten Sizilien. München: Droemer Knaur, 1995.

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Die Seherin von Garmisch: Oberbayern-Krimi ; [Schwemmers zweiter Fall]. Augsburg: Weltbild, 2013.

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Der Engelspapst: Roman. Bern: Scherz, 2000.

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Book chapters on the topic "MoRF"

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Gewies, Andreas, Jürgen Ruland, Alexey Kotlyarov, Matthias Gaestel, Shiri Procaccia, Rony Seger, Shin Yasuda, et al. "MORF." In Encyclopedia of Signaling Molecules, 1114. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100843.

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Morf, Carolyn C. "Morf, Carolyn C." In Encyclopedia of Personality and Individual Differences, 2990–93. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-24612-3_2247.

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Gewies, Andreas, Jürgen Ruland, Alexey Kotlyarov, Matthias Gaestel, Shiri Procaccia, Rony Seger, Shin Yasuda, et al. "MORF Lysine Acetyltransferase." In Encyclopedia of Signaling Molecules, 1114. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100844.

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Morf, Carolyn C. "Morf, Carolyn C." In Encyclopedia of Personality and Individual Differences, 1–4. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-28099-8_2247-1.

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Zhang, Jiang-Ping, Xiaoyu Du, Kezhi Yan, and Xiang-Jiao Yang. "MOZ and MORF Lysine Acetyltransferases." In Encyclopedia of Signaling Molecules, 3208–14. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_510.

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Zhang, Jiang-Ping, Xiaoyu Du, Kezhi Yan, and Xiang-Jiao Yang. "MOZ and MORF Lysine Acetyltransferases." In Encyclopedia of Signaling Molecules, 1–7. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_510-1.

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Gewies, Andreas, Jürgen Ruland, Alexey Kotlyarov, Matthias Gaestel, Shiri Procaccia, Rony Seger, Shin Yasuda, et al. "MOZ and MORF Lysine Acetyltransferases." In Encyclopedia of Signaling Molecules, 1115–19. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_510.

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Wu, Yi-Leh, Edward Y. Chang, Kwang-Ting Cheng, Cheng-Wei Chang, Chen-Cha Hsu, Wei-Cheng Lai, and Ching-Tung Wu. "MORF: A Distributed Multimodal Information Filtering System." In Advances in Multimedia Information Processing — PCM 2002, 279–86. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-36228-2_35.

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Dressler, Wolfgang U., and Lavinia Merlini Barbaresi. "Morphopragmatics." In Handbook of Pragmatics, 977–86. Amsterdam: John Benjamins Publishing Company, 2022. http://dx.doi.org/10.1075/hop.m2.mor1.

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Dressler, Wolfgang U., and Lavinia Merlini Barbaresi. "Morphopragmatics." In Handbook of Pragmatics, 1–14. Amsterdam: John Benjamins Publishing Company, 1999. http://dx.doi.org/10.1075/hop.3.mor1.

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Conference papers on the topic "MoRF"

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Desbiez, A., F. Expert, M. Boyron, J. Diperi, S. Viollet, and F. Ruffier. "X-Morf: A crash-separable quadrotor that morfs its X-geometry in flight." In 2017 Workshop on Research, Education and Development of Unmanned Aerial Systems (RED-UAS). IEEE, 2017. http://dx.doi.org/10.1109/red-uas.2017.8101670.

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Lu, Chengwu. "Image Denoising Based on MORF and Minimization Total Variation." In Eighth ACIS International Conference on Software Engineering, Artificial Intelligence, Networking, and Parallel/Distributed Computing (SNPD 2007). IEEE, 2007. http://dx.doi.org/10.1109/snpd.2007.299.

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Di Fina, Dario, Svebor Karaman, Andrew D. Bagdanov, and Alberto Del Bimbo. "MORF: Multi-Objective Random Forests for face characteristic estimation." In 2015 12th IEEE International Conference on Advanced Video and Signal Based Surveillance (AVSS). IEEE, 2015. http://dx.doi.org/10.1109/avss.2015.7301793.

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Wang, Daoye, Prashanth Chandran, Gaspard Zoss, Derek Bradley, and Paulo Gotardo. "MoRF: Morphable Radiance Fields for Multiview Neural Head Modeling." In SIGGRAPH '22: Special Interest Group on Computer Graphics and Interactive Techniques Conference. New York, NY, USA: ACM, 2022. http://dx.doi.org/10.1145/3528233.3530753.

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Docksteader, Luke, and Rachid Benlamri. "Mobile Ontology-based Reasoning and Feedback (MORF) Health Monitoring System." In 2008 Third International Conference on Digital Information Management (ICDIM). IEEE, 2008. http://dx.doi.org/10.1109/icdim.2008.4746831.

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Thomas, Grant, Jeremy Banik, Thomas Murphey, David Wilt, and Joseph Footdale. "Modular Reconfigurable Zero Free-Play (MORF) Solar Array Deployment Concept Verification." In 53rd AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics and Materials Conference
20th AIAA/ASME/AHS Adaptive Structures Conference
14th AIAA. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2012. http://dx.doi.org/10.2514/6.2012-1950.

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Gardner, Josh, Christopher Brooks, Juan Miguel Andres, and Ryan S. Baker. "MORF: A Framework for Predictive Modeling and Replication At Scale With Privacy-Restricted MOOC Data." In 2018 IEEE International Conference on Big Data (Big Data). IEEE, 2018. http://dx.doi.org/10.1109/bigdata.2018.8621874.

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Arlitt, Ryan, Charles Manion, Robert Stone, Matthew Campbell, and Irem Tumer. "Using Molecular Fingerprinting to Infer Functional Similarity in Engineered Systems." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46888.

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Design of new and advanced materials with shape-shifting or origami-like capabilities is an area that bears a strong similarity to the design of electromechanical products yet has not leveraged such systematic approaches. In this paper, computational methods to design Metal Organic Responsive Frameworks (MORFs) — which are a theoretical type of material that can change their shape and porosity in response to light — are investigated. However, it is a significant challenge to computationally identify MORFs that are both feasible and useful, i.e., systemic invention (as opposed to discovery) of new MORFs. The proposed framework utilizes the typical product design process to iteratively generate new candidates, evaluate their properties, and then guide the generation of the next set of candidates. A materials designer could then leverage this knowledge to generate structures or substructures with specific functional goals in mind. In this paper an approach to inferring functional similarity of systems using structural information — based on both drug design and database-driven product design — is evaluated. The results demonstrate an observable correlation between structural fingerprints of electromechanical products and electromechanical function. This evidence, combined with the well-established similar property principle in drug design, supports the usage of molecular fingerprinting for providing high-level functional guidance in a MORF design framework based on purely structural information.
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Scheffler, John. "Flipping the College Classroom by Reflective Practice." In Engineering Something More. Iowa City, Iowa: University of Iowa, 2014. http://dx.doi.org/10.17077/aseenmw2014.1022.

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Chiusano, Robert. "Keynote." In Engineering Something More. Iowa City, Iowa: University of Iowa, 2014. http://dx.doi.org/10.17077/aseenmw2014.1000.

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Reports on the topic "MoRF"

1

Duggan, Mark. More Guns, More Crime. Cambridge, MA: National Bureau of Economic Research, October 2000. http://dx.doi.org/10.3386/w7967.

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Rizzo, Thomas G. More and More Indirect Signals for Extra Dimensions at More and More Colliders. Office of Scientific and Technical Information (OSTI), January 1999. http://dx.doi.org/10.2172/9989.

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Schissler, Mark O. Coalition Warfare: More Power or More Problems? Fort Belvoir, VA: Defense Technical Information Center, June 1993. http://dx.doi.org/10.21236/ada264186.

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Finger, J. Michael, and Ann Harrison. The MFA Paradox: More Protection and More Trade? Cambridge, MA: National Bureau of Economic Research, May 1994. http://dx.doi.org/10.3386/w4751.

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Pastor, Lubos, Robert Stambaugh, and Lucian Taylor. Do Funds Make More When They Trade More? Cambridge, MA: National Bureau of Economic Research, November 2014. http://dx.doi.org/10.3386/w20700.

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Rabe, Birgitta, Mike Brewer, Sarah Cattan, and Claire Crawford. Does more free childcare help parents work more? The IFS, December 2016. http://dx.doi.org/10.1920/wp.ifs.2016.1622.

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Rabe, Birgitta, Claire Crawford, Sarah Cattan, and Mike Brewer. Does more free childcare help parents work more? The IFS, March 2020. http://dx.doi.org/10.1920/wp.ifs.2020.920.

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Killourhy, Kevin S., and Roy A. Maxion. Should Security Researchers Experiment More and Draw More Inferences? Fort Belvoir, VA: Defense Technical Information Center, August 2011. http://dx.doi.org/10.21236/ada547672.

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Cheong, Yeonhee. Memento Mori Sewol. Ames: Iowa State University, Digital Repository, November 2015. http://dx.doi.org/10.31274/itaa_proceedings-180814-1277.

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Stulz, René, Dimitrios Vagias, and Mathijs van Dijk. Do Firms Issue more equity when markets are more liquid? Cambridge, MA: National Bureau of Economic Research, July 2013. http://dx.doi.org/10.3386/w19229.

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