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S, Satish, Minnu Sara Sam, and A. R. Shabaraya. "Assessing the Role of Knowledge, Awareness, Practice in Achieving Medication Adherence among Hypertensive Patients." International Journal of Research and Review 8, no. 5 (2021): 324–29. http://dx.doi.org/10.52403/ijrr.20210541.
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Medication adherence is that the degree to which the person's behaviour corresponds with the agreed recommendations from a health care provider. Knowledge and the awareness concerning the hypertension and the antihypertensive medications have an important role within the medication adherence, lack of this can have negative impact on the medication adherence. The assessment of medication adherence in the study was meted out by using morisky scale. It’s a cross sectional study conducted in 150 individuals in Kankanady, Valachil, Valencia, Jeppu, Padil of Mangalore in Karnataka. Patient data collection forms were used to collect the information. Present study reflected that patients had knowledge regarding normal BP, symptoms and complications, however majority thinks hypertension can be curable. A positive attitude and practice were observed among the patients apart from practice of normal exercise. Analysing the data using MAMS-8 scale, study showed only 11.3% of the population were found to be high adherent that shows the decrease in the adherence rates. 34% had moderate adherence and the remaining 54% were low adherent. Assessment of data suggests that majority lack complete information about hypertension and its management. The study results revealed that hypertension related knowledge, awareness and practice plays a serious role in improving medication adherence. Keywords: Medication adherence, Hypertension, Knowledge, Awareness, Morisky scale.
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Zongo, Arsène, Line Guénette, Jocelyne Moisan, Laurence Guillaumie, Sophie Lauzier, and Jean-Pierre Grégoire. "Revisiting the internal consistency and factorial validity of the 8-item Morisky Medication Adherence Scale." SAGE Open Medicine 4 (January 1, 2016): 205031211667485. http://dx.doi.org/10.1177/2050312116674850.
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Objective: To assess the internal consistency and factorial validity of the adapted French 8-item Morisky Medication Adherence Scale in assessing adherence to noninsulin antidiabetic drug treatment. Study Design and Setting: In a cross-sectional web survey of individuals with type 2 diabetes of the Canadian province of Quebec, self-reported adherence to the antidiabetes drug treatment was measured using the Morisky Medication Adherence Scale-8. We assessed the internal consistency of the Morisky Medication Adherence Scale-8 with Cronbach’s alpha, and factorial validity was assessed by identifying the underlying factors using exploratory factor analyses. Results: A total of 901 individuals completed the survey. Cronbach’s alpha was 0.60. Two factors were identified. One factor comprised five items: stopping medication when diabetes is under control, stopping when feeling worse, feeling hassled about sticking to the prescription, reasons other than forgetting and a cross-loading item (i.e. taking drugs the day before). The second factor comprised three other items that were all related to forgetfulness in addition to the cross-loading item. Conclusion: Cronbach’s alpha of the adapted French Morisky Medication Adherence Scale-8 was below the acceptable value of 0.70. This observed low internal consistency of the scale is probably related to the causal nature of the items of the scale but not necessarily a lack of reliability. The results suggest that the adapted French Morisky Medication Adherence Scale-8 is a two-factor scale assessing intentional (first factor) and unintentional (second factor) non-adherence to the noninsulin antidiabetes drug treatment. The scale could be used to separately identify these outcomes using scores obtained on each of the sub-scales.
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Zyryanov, Sergey K., Sergey B. Fitilev, Alexander V. Vozzhaev, et al. "Medication adherence in patients with stable coronary artery disease in primary care." Research Results in Pharmacology 6, no. (2) (2020): 97–103. https://doi.org/10.3897/rrpharmacology.6.54130.
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Introduction: Lack of research targeting non-adherence to cardiovascular medications in Russia prevents from developing effective interventions to improve adherence. The aim was to study medication adherence in patients with stable coronary artery disease in primary care. Material and methods: The study was conducted in a primary care setting of Moscow. Demography, medical history, pharmacotherapy data were obtained retrospectively from 386 coronary patients' medical records. Medication adherence was measured by 8-item Morisky Medication Adherence Scale (MMAS-8). A statistical analysis was performed using SPSS Statistics V16.0. Results and discussion: According to the results from MMAS-8, 188 (48.7%) coronary patients had high medication adherence, 135 (35.0%) – moderate, and 63 (16.3%) – low. By the dichotomous interpretation: 48.7% (n = 188) – were adherent, 51.3% (n = 198) – were non-adherent. These groups were similar in gender distribution, age, and medical history profile (p > 0.1 for all variables). Smokers prevailed in the non-adherent group (13.6 vs. 5.3%; p = 0.009). Both groups were equally prescribed beta-blockers, antiplatelets, and statins (p > 0.1 for all). Use of fixed dose combinations (11.7 vs. 5.6%; p = 0.048) and the number of pills taken (mean 5.64 ± 1.52 vs. 5.99 ± 1.62; p = 0.029) were associated with better adherence. Higher values of total cholesterol (mean 5.2 ± 1.4 vs. 4.7 ± 1.2 mmol/L; p < 0.001) and low-density lipoprotein cholesterol (mean 2.9 ± 1.2 vs. 2.4 ± 0.9 mmol/L; p < 0.001) were revealed in non-adherents. Subjects with suboptimal adherence visited general practitioners more frequently (median 5 vs. 3 visits; p = 0,003). Conclusion: Medication non-adherence in coronary outpatients exceeded 50%. High adherence was associated with more frequent use of fixed dose combinations and fewer pills taken by patient. Smoking and poorer control of blood lipids prevailed in non-adherents, who also caused higher load on general practitioners.
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Arunachalam, Divya Priya, Uma Maheswari, and Damodaran. "IJCM_195A: Prevalence of Drug Adherence Among Hypertensive Patients attending Primary Health Centre - A Cross sectional Study." Indian Journal of Community Medicine 49, Suppl 1 (2024): S57. http://dx.doi.org/10.4103/ijcm.ijcm_abstract195.
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Background: There is an increase in prevalence of hypertension 31.5% in urban and 26.2% in rural dwellers of Tamil Nadu (ICMR-INDIAB study). Adherence to hypertension medication is very important for improving the quality of life and preventing complications. In this study we aim to estimate the drug adherence among hypertensive patients using Morisky Medication Adherence Scale. Objectives: To estimate the prevalence of drug adherence and its influencing factors among hypertensive patients in Rural Health Training Centre areas of Madras Medical College. Methodology: 180 Hypertensive patients attending Non-Communicable Disease clinic from two rural health centres 90 patients from each Padiyanallur PHC and Medavakkam PHC were recruited for the study. In this study we have used The Morisky Scale MMAS-4 to address medication adherence. Results: Study results showed that 32.62% of hypertensive patients had high adherence to antihypertensive medications,53.48% patients had medium adherence whereas 13.9% patients had low adherence. Adherence to drug is higher among females (36.9%) than males (29.1%). Patients with low to medium adherence to antihypertensive drugs are having more than 10% risk of developing cardiovascular disease (OR – 3.6, 95% CI – 1.86 to 6.75) than their counterpart. Patients with good knowledge (42%) had high adherence than people with poor knowledge (24.2%) Conclusion: The study reported only 32.62% were found to be adherent to antihypertensive medications. To ensure high level of control among hypertensive sustained and focussed interventions should be implemented at all levels of health care.
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Lee, Gabrielle K. Y., Harry H. X. Wang, Kirin Q. L. Liu, Yu Cheung, Donald E. Morisky, and Martin C. S. Wong. "Determinants of Medication Adherence to Antihypertensive Medications among a Chinese Population Using Morisky Medication Adherence Scale." PLoS ONE 8, no. 4 (2013): e62775. http://dx.doi.org/10.1371/journal.pone.0062775.
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Hrishikesh, Gupta* Punam Kela Raghavendra Bhutada Rahul Pethe. "IMPACT ANALYSIS OF PATIENT COUNSELLING ON MEDICATION ADHERENCE IN PATIENTS SUFFERING FROM HYPERTENSION AT DISTRICT GENERAL HOSPITAL AMRAVATI." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 01 (2018): 359–63. https://doi.org/10.5281/zenodo.1154342.
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Background: Hypertension is one of the leading causes of deaths and is regarded as silent killers that have caused approx. 2.3 million deaths in India in 1990’s and this figure of deaths is supposed to be doubled by 2020. Objective: The sole objective of the study was to assess the medication adherence of the patients before and after counseling and to analyze the impact of patient counseling in patients. Methods: A cross sectional study was conducted at the District General Hospital, Amravati using Morisky-8 Medication Adherence scale in patient with hypertension without any co-morbidity. Results: Study performed on 132 subjects revealed that 77% of the subjects shown low adherence while only 5% shown complete medication adherence before counseling. After counseling, the subjects who were compliant with the therapy rose to 41% while those who weren’t compliant decreased to 11%. Two way ANOVA analysis of the data obtained revealed that there was significant improvement (P<0.0001) in medication adherence and medication knowledge. Key words: Patient counseling, Medication adherence, Hypertension, Morisky Scale, Patient information Leaflet
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Khdour, Maher R., Heba B. Awadallah, Mustafa A. Alnadi, and Doaa H. Al-Hamed. "Beliefs About Medicine and Glycemic Control Among Type 2 Diabetes Patients: A Cross-Sectional Study in West Bank, Palestine." Journal of Primary Care & Community Health 11 (January 2020): 215013272097191. http://dx.doi.org/10.1177/2150132720971919.
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Introduction: To examine the mean differences between patient beliefs about medicine with reference to adherence and glycemic control. Methods: This study utilized a cross-sectional questionnaire-based approach. Adherence to medication was measured with the Morisky Green Levine Medication Adherence Scale (MGLS); glycemic control as the last HbA1c test value; and beliefs about medicine with the Beliefs about Medicines Questionnaire (BMQ). Results: According to MGLS scale, 220 (57.9%) of the diabetic patients were classified as high adherent to their medications and 160 (42.1%) were classified as low adherent. Patients had strong believes in their medication, the mean necessity score was significantly outweighed the mean concerns score (17.7 vs 14.4; P < .001). Low adherent patients had significantly more concerns about long term effect of medications (14.4 vs 13.8; P < .008). No significant mean differences were found between glycemic controlled and uncontrolled group regarding necessity or concern domains. Conclusion: Assessing beliefs about medicine is crucial for recognizing patients at risk of low adherence, which offers a way to help patients with diabetes to achieve a better glycemic control.
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Dr., Saba Bashir Dr. Mudassar Murtaza Dr. Tasbiha Hasnain. "NON-ADHERENCE IN HYPPERTENSIVE PATIENTS OF PESHAWAR, PAKISTAN." Indo American Journal of Pharmaceutical Sciences 05, no. 04 (2018): 3097–109. https://doi.org/10.5281/zenodo.1236751.
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<strong><em>Introduction: </em></strong><em>Hypertension is a major risk factor for cardiovascular morbidity and mortality. Adherence to anti-hypertensive treatment plays an important role in controlling hypertension and reducing mortality and morbidity associated with cardiovascular events.</em> <strong><em>Objectives: </em></strong><em>The objectives of this study were to determine the frequency of adherent patients among a sample of Peshawar’s population, awareness of hypertension in non-adherent patients and to demonstrate the factors responsible for non-adherence in hypertensive patients.</em> <strong><em>Methodology: </em></strong><em>It was a quantitative, descriptive, cross-sectional questionnaires based study carried out from 05-12-2013 to 18-03-2014. A convenient sample of 100 hypertensive patients (60 females & 40 males) was gathered from Hayatabad, Phase-4, Peshawar. To assess adherence, 8 item Morisky medication adherence scale was used, whereas, factors were reported via structured questionnaire. Data was analyzed using SPSS v21 and Microsoft Excel 2013 was used for graphs.</em> <strong><em>Results: </em></strong><em>In our study, 68% of the patients were non-adherent. The mean MMAS score was 5.33 (SD= ± 2.49). Overall awareness of hypertension in non-adherent patients regarding importance of medication use , skipping a dose affect BP, and about cause of hypertension was 95.6%, 60.3% and 91.2% respectively. Among demographic factors, only socioeconomic status was significantly associated with adherence (p=0.02). The top three medication related factors responsible for non-adherence were forgetfulness, (61.76%), symptomless (58.82%) and fear of addiction (51.47%).</em> <strong><em>Conclusion: </em></strong><em>Different interventions at the level of families of hypertensive patients regarding reducing forgetfulness should be introduced. People should be educated to use the medicine continuously and about the fear of addiction to anti-hypertensive medication via mass media.</em> <strong>Keywords: </strong>Non-adherence, hypertension, Morisky medication adherence scale, lifestyle modification.
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Jannuzzi, Fernanda Freire, Fernanda Aparecida Cintra, Roberta Cunha Matheus Rodrigues, Thaís Moreira São-João, and Maria Cecília Bueno Jayme Gallani. "Medication adherence and quality of life among the elderly with diabetic retinopathy." Revista Latino-Americana de Enfermagem 22, no. 6 (2014): 902–10. http://dx.doi.org/10.1590/0104-1169.3477.2494.
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METHOD: one hundred (n=100) elderly outpatients with diabetic retinopathy taking antihypertensives and/or oral antidiabetics/insulin were interviewed. Adherence was evaluated by the adherence proportion and its association with the care taken in administrating medications and by the Morisky Scale. The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) was used to evaluate HRQoL.RESULTS: most (58%) reported the use of 80% or more of the prescribed dose and care in utilizing the medication. The item "stopping the drug when experiencing an adverse event", from the Morisky Scale, explained 12.8% and 13.5% of the variability of adherence proportion to antihypertensives and oral antidiabetics/insulin, respectively.CONCLUSION: there was better HRQoL in the Color Vision, Driving and Social Functioning domains of the NEI VFQ-25. Individuals with lower scores on the NEI VFQ-25 and higher scores on the Morisky Scale presented greater chance to be nonadherent to the pharmacological treatment of diabetes and hypertension.
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Getenet, Atsede, Mulugeta Tesfa, Aster Ferede, and Yalew Molla. "Determinants of adherence to anti-hypertensive medications among adult hypertensive patients on follow-up in Hawassa Referral Hospital: A case–control study." JRSM Cardiovascular Disease 8 (January 2019): 204800401989275. http://dx.doi.org/10.1177/2048004019892758.
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Introduction Hypertension is a global challenge which accounts for high morbidity and mortality rates in the world. The availability of effective anti-hypertensive medications does not result in a good outcome in controlling blood pressure which points towards poor adherence. Thus, this study was conducted to assess the determinants of adherence to anti-hypertensive medication among hypertensive patients on follow-up in Hawassa Referral Hospital. Methods Institution-based case–control study was conducted on a sample of 289 clients from February to May 2018. Census was conducted on 1600 clients to select cases and controls. Then, systematic random sampling was used to select study subjects, and adherence was measured by Morisky medication adherence scale. The associations of variables were analyzed using bivariable followed by multivariable logistic regression analyses. Results The respondent’s adherence to medication was found to be 67% as measured by Morisky medication adherence scale. The multivariate logistic regression analysis showed that medication adherence was found to be better in younger age (<45) (AOR = 3.8), clients living in urban areas (AOR = 6.84), those clients who had good knowledge (AOR = 3.13), those with no co-morbidities (AOR = 3.14) and patients who controlled their blood pressure (<140/90) (AOR = 2.35). Conclusions The rate of medication adherence was found to be low, and hence educational interventions focusing on factors promoting adherence and patients’ health support should be implemented.
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Kelly, Michael S., Leticia R. Moczygemba, and Sharon S. Gatewood. "Concordance of Pharmacist Assessment of Medication Nonadherence With a Self-Report Medication Adherence Scale." Journal of Pharmacy Practice 29, no. 3 (2014): 194–98. http://dx.doi.org/10.1177/0897190014550003.
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Objective: To evaluate the concordance of the Modified Morisky Scale (MMS) with a pharmacist assessment of medication adherence during a medication review. Methods: This retrospective study examined the electronic medical records (EMRs) of patients ≥18 years who received a medication review by a pharmacist from October 2008 to September 2009 at a homeless behavioral health clinic. In addition to the 6-item MMS, adherence was assessed using the first 4 items of the MMS, which comprise the original Morisky Scale. A final pharmacist assessment of adherence based upon the medication review was documented in the EMR. The McNemar test was used to assess the agreement between the MMS (6 and 4 items) and the pharmacist assessment of medication adherence. Results: A total of 288 patients were eligible for the study, which included 449 medication reviews. Nonadherence was identified in 61.7% and 49.7% of medication reviews using the 6 and 4 items of the MMS. The pharmacist assessment determined nonadherence in 23.8% of medication reviews. There were significant differences between the pharmacist adherence assessment and the 6 ( P < .0001) and 4 ( P < .0001) items of the MMS. Conclusion: A combination of methods including self-report and pharmacist assessment may provide the greatest insight into adherence.
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Thomas, Nezbile F., and Karen S. Dunn. "Self-Transcendence and Medication Adherence in Older Adults With Hypertension." Journal of Holistic Nursing 32, no. 4 (2014): 316–26. http://dx.doi.org/10.1177/0898010114528379.
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Purpose: The purpose of this study was to examine the relationship between self-transcendence and medication adherence among older adults prescribed antihypertensive medication. Design: Descriptive, correlational research design. Method: Forty-six older adults who were prescribed antihypertensive medications from an independent living facility participated in this study. Participants were given a survey that included a demographic questionnaire, the Morisky Medication Adherence Scale, and Reed’s Self-Transcendence Scale. Findings: No significant relationship was found between medication adherence and self-transcendence ( r = −.20, p = .18). Ninety percent of the participants however, admitted to cutting back or stopping their medication without notifying their providers. Conclusion: Continued investigation is needed to identify reasons why older adults fail to adhere to taking prescribed hypertension medications in order to improve health outcomes in this population.
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Bou Serhal, R., P. Salameh, N. Wakim, et al. "A New Lebanese Medication Adherence Scale: Validation in Lebanese Hypertensive Adults." International Journal of Hypertension 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/3934296.
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Background. A new Lebanese scale measuring medication adherence considered socioeconomic and cultural factors not taken into account by the eight-item Morisky Medication Adherence Scale (MMAS-8). Objectives were to validate the new adherence scale and its prediction of hypertension control, compared to MMAS-8, and to assess adherence rates and factors. Methodology. A cross-sectional study, including 405 patients, was performed in outpatient cardiology clinics of three hospitals in Beirut. Blood pressure was measured, a questionnaire filled, and sodium intake estimated by a urine test. Logistic regression defined predictors of hypertension control and adherence. Results. 54.9% had controlled hypertension. 82.4% were adherent by the new scale, which showed good internal consistency, adequate questions (KMO coefficient = 0.743), and four factors. It predicted hypertension control (OR = 1.217; p value = 0.003), unlike MMAS-8, but the scores were correlated (ICC average measure = 0.651; p value < 0.001). Stress and smoking predicted nonadherence. Conclusion. This study elaborated a validated, practical, and useful tool measuring adherence to medications in Lebanese hypertensive patients.
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Abdul Ghafur, Nur Aina, Syahrir Zaini, and Hussam Mizher. "Assessment of Methods to Measure Adherence of Antidepressants: A Systematic Review." Journal of Pharmacy 4, no. 2 (2024): 260–78. https://doi.org/10.31436/jop.v4i2.287.
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Adherence towards antidepressant agents is a vital element in effectively managing depression. Non-adherence of antidepressants can lead to a recurrence of depressive symptoms and decreased treatment effectiveness. Adherence is assessed using various types of measures. This study aims to evaluate the different methods used to assess the adherence towards antidepressants on adults with depression. This systematic review adhered to the guidelines outlined in the PRISMA statement. PubMed, Cochrane Library, and Scopus are searching from 2013 to 2023 for articles that studied or reported on antidepressant adherence measures in adults with depression. Two authors conducted independent screenings of the articles against the eligibility criteria, examining titles, abstracts, and full-texts. The risk of bias for all included studies were assessed using the Joanna Briggs Institute (JBI) critical appraisal checklists. Information from all the selected articles was extracted using a predefined table. 15 studies met the eligibility criteria. When measuring adherence towards antidepressant at initiation and/or implementation phase, self-report methods such as Medication Adherence Rating Scale (MARS) demonstrated acceptable reliability and validity, while Brief Medication Questionnaire (BMQ by Svarstad et al.), Morisky Medication Adherence Questionnaire (MAQ), and Brief Adherence Rating Scale (BARS) showed good validity, and Morisky Medication Adherence Scale (MMAS), Morisky Green Levine Adherence (MGLA), Beliefs about Medicine Questionnaire (BMQ by Horne et al.) and Drug Attitude Inventory (DAI-10) showed good reliability. This study found a diverse range of methods to measure adherence towards antidepressant in adults. Self-report assessments, particularly in primary care and psychiatric settings, emerged as the most practical tools followed by clinician-rating scale, pharmacy refill data, adherence scale, pill count, and average serum level. No single measure with consistently shown strong reliability and validity across different adherence stages, highlighting the need for a combined approach.
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Mohammad Javad Hashemi, Mohammad Manaf, Bhanu Priya HR, Laween Merris Lenos, Prabhu M, and Ragunatha S. "A descriptive study of factors associated with anti-fungal medication adherence among patients with dermatophytosis." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 7027–33. http://dx.doi.org/10.26452/ijrps.v11i4.3806.
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The prevalence of superficial Mycotic infection worldwide is 20–25%. Medication non-adherence in patients leads to worsening of the disease, death and increased health care costs. More than 30% of medicine-related hospital admissions occur due to medication non-adherence. The aim of the study is assessing the factors associated with medication adherence in patients with dermatophytosis. Data were analyzed by using descriptive analysis of 305 patients attending the dermatology department. The period of study was three months. Medication adherence was determined using Morisky Green Levine Scale for dermatophytosis patients who are undergoing treatment. KAP (knowledge, attitude, practice) was used to determine the knowledge gaps, general health practice, and beliefs of the patient towards fungal infection. It was found that 47.86% of the subjects in the study are non- adherent and 49.50% are moderate adherents, and only 2.62% are highly adherent to medications prescribed. In KAP study, it was found that (14.4%) strongly agree that fungal infection does not create hindrance in normal life, while (28.85%) strongly disagree. Practice where analyzed in 305 subjects, (52.13%) share clothing with family members or friends, (50.16%) do not take medication as prescribed. The patient affected with fungal infections had poor adherence to the medicines prescribed. The risk factors affecting medication adherence are poor hygiene, sharing of cloths of friends or family, dosing schedule, complex regimens, access barriers, and cost of the drug. Patient education, in the early stages of fungal infection, can avoid non- adherence.
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Ahlawat, Saurabh, Vikrant Aggarwal, and Rakesh Kumar. "Medication compliance in schizophrenic out patients with psychoactive substance use co-morbidity: a cross-sectional study." International Journal of Research in Medical Sciences 10, no. 1 (2021): 167. http://dx.doi.org/10.18203/2320-6012.ijrms20215049.
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Background: Medication adherence is an important issue in the treatment and management of persons with psychiatric disorders including schizophrenia. Apart from side effects and inefficient outcomes of psychiatric medications, substance abuse also complicates the adherence pattern to the prescribed medications. Present study was designed to estimate the magnitude of medication non-adherence and its correlates in patients with schizophrenia having co-morbid psychoactive substance use.Method: The 60 schizophrenic patients with active substance use were taken from OPD of institute of mental health and hospital, Agra. Positive and negative syndrome scale (PANSS), alcohol, smoking and substance involvement screening test (ASSIST), medication adherence rating scale (MARS) and Morisky 8-item medication adherence questionnaire (MMAQ-8) were used to gather relevant clinical data along with a proforma for recording socio-demographic characteristics.Results: The results revealed an alarming level of medication adherence. The 91.7% sample (55 patients) met the criteria for medication non-adherence. Majority of the patients were using alcohol (58.3%) and cannabis (51.7%). Conclusions: Given the high rate of medication non-compliance it is suggested that specific intervention aimed at compliance to prescribed medication is needed in this population.
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Horvat, Nejc, Igor Locatelli, Mitja Kos, and Ana Janežič. "Medication adherence and health-related quality of life among patients with chronic obstructive pulmonary disease." Acta Pharmaceutica 68, no. 1 (2018): 117–25. http://dx.doi.org/10.2478/acph-2018-0006.
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Abstract This study evaluated medication adherence and health-related quality of life (HRQoL) of Slovenian patients with chronic obstructive pulmonary disease (COPD) and examined the factors associated with HRQoL. Demographic and therapy information was collected from 65 patients through interviews. The St. George’s Respiratory Questionnaire and the Morisky Medication Adherence Scale were used to evaluate HRQoL and adherence, resp. A multiple linear regression model was used to assess the association between the factors and HRQoL. The mean St. George’s Respiratory Questionnaire score (range 0-100, with higher scores indicating lower HRQoL) was 41.4. COPD affected patients’ daily activities more than their social and psychological functioning. Slightly more than 53 % of the patients were optimally adherent, while 12 % were non-adherent. Patients with lower HRQoL had a larger number of medications for concomitant diseases, experienced COPD exacerbation in the last year, and had less education. No statistically significant correlation was found between medication adherence and HRQoL.
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Awwad, Oriana, Suha AlMuhaissen, Ayat Al-Nashwan, and Salahdein AbuRuz. "Translation and validation of the Arabic version of the Morisky, Green and Levine (MGL) adherence scale." PLOS ONE 17, no. 10 (2022): e0275778. http://dx.doi.org/10.1371/journal.pone.0275778.
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The Morisky Green Levine (MGL) adherence scale is a 4-item tool used for the detection of medication nonadherence among patients with chronic health conditions. Despite being widely used in Arabic-speaking research contexts, it has never been validated in Arabic language. The aim of this study was to translate and validate the MGL tool into Arabic. A standard forward-backward process was used to translate the questionnaire. Cronbach’s alpha coefficient was measured to assess internal consistency of the scale. The test-retest reliability measured the consistency of participants’ responses over time. Construct validity was evaluated by Explanatory factor analysis (EFA); Kaiser-Meyer-Olkin value and Bartlett’s test of sphericity were determined. Convergent validity was assessed using a preexisting medications Arabic Adherence Assessment Tool (AAAT). The model fit was evaluated using confirmatory factor analysis (CFA). Associations between the MGL scale scores and the patient demographic/clinical characteristics were tested by linear regressions. A total of 201 participants were included into the study. The MGL scale categorization revealed that 20.9%, 59.2% and 19.9% of the participants had high, moderate and low levels of adherence respectively. Adequate internal consistency (alpha = 0.593) was observed. A significant strong ICC and Pearson’s correlations were generated between responses at time 1 and time 2. EFA results elucidated the suitability of the data for factor analysis. Pearson’s coefficient (r) revealed a significant strong correlation between MGL scale and AAAT. CFA results confirmed a good fit for the suggested model. Linear regression revealed higher number of medications, more frequent outpatient clinic visits and not experiencing medication adverse effect factors significantly associated with better adherence. The Arabic version of MLG scale is a reliable valid tool to assess adherence among Arabic-speaking communities. Implementing interventions targeting patients not compliant to regular clinic visits and those at higher risk of experiencing medication side effects can greatly enhance medication adherence.
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George, Nimmy Elizabeth, Smrithy Sunny, Anitta Mariyam Sam, Aleena Susan Sabu, and Prudence A. Rodrigues. "EFFECT OF MEDICATION RELATED EDUCATIONAL INTERVENTIONS ON IMPROVING MEDICATION ADHERENCE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 167. http://dx.doi.org/10.22159/ajpcr.2017.v11i1.22238.
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Objectives: To assess the patient medication adherence using 8 item morisky medication adherence scale (MMAS). To categorize patients based on their adherence to antidiabetic medications into low, medium, and high adherent. To provide educational interventions such as patient counseling using teach-back method, patient medication information leaflet, and audio-visual aids and thus to improve the patient medication adherence.Methods: After obtaining informed consent from the patients, data of the patients were recorded in data collection forms. Their adherence to antidiabetic medication was evaluated using 8 item MMAS and patients were categorized into low, medium, and high adherence groups based on the score. Counseling was done based on the categorization (high, medium, and low). During review, again adherence was rechecked using 8 item MMAS.Results: Medication adherence was measured using 8 item MMAS on review and adherence was found to be improved using different patient counseling methods according to their adherence category. Improvement in score within low adherence group was found to be 83.87%; improvement of the low adherence group to medium adherence group was 16.12%. Improvement within the medium adherence group was 82.14% and from medium adherence to high adherence group was 17.85%.Conclusion: Patient counseling can improve adherence in type 2 diabetes mellitus patients, which in turn help patients in achieving optimal glycemic control.
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George, Nimmy Elizabeth, Smrithy Sunny, Anitta Mariyam Sam, Aleena Susan Sabu, and Prudence A. Rodrigues. "EFFECT OF MEDICATION RELATED EDUCATIONAL INTERVENTIONS ON IMPROVING MEDICATION ADHERENCE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 1 (2018): 167. http://dx.doi.org/10.22159/ajpcr.2018.v11i1.22238.
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Objectives: To assess the patient medication adherence using 8 item morisky medication adherence scale (MMAS). To categorize patients based on their adherence to antidiabetic medications into low, medium, and high adherent. To provide educational interventions such as patient counseling using teach-back method, patient medication information leaflet, and audio-visual aids and thus to improve the patient medication adherence.Methods: After obtaining informed consent from the patients, data of the patients were recorded in data collection forms. Their adherence to antidiabetic medication was evaluated using 8 item MMAS and patients were categorized into low, medium, and high adherence groups based on the score. Counseling was done based on the categorization (high, medium, and low). During review, again adherence was rechecked using 8 item MMAS.Results: Medication adherence was measured using 8 item MMAS on review and adherence was found to be improved using different patient counseling methods according to their adherence category. Improvement in score within low adherence group was found to be 83.87%; improvement of the low adherence group to medium adherence group was 16.12%. Improvement within the medium adherence group was 82.14% and from medium adherence to high adherence group was 17.85%.Conclusion: Patient counseling can improve adherence in type 2 diabetes mellitus patients, which in turn help patients in achieving optimal glycemic control.
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Sakthong, Phantipa, Rossamalin Chabunthom, and Rungpetch Charoenvisuthiwongs. "Psychometric Properties of the Thai Version of the 8-item Morisky Medication Adherence Scale in Patients with Type 2 Diabetes." Annals of Pharmacotherapy 43, no. 5 (2009): 950–57. http://dx.doi.org/10.1345/aph.1l453.
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Background A self-reporting questionnaire is the most convenient and cheapest way to assess medication adherence. A new 8-item self-reported Morisky Medication Adherence Scale (MMAS) has been developed and has shown better psychometric properties than the original 4-item Morisky scale. Objective To examine the validity, including convergent known-groups and construct validity, and reliability, including internal consistency and test–retest reliability, of the MMAS in Thai patients with type 2 diabetes. Methods The data were derived from a cross-sectional study. In a convenience sample, 303 type 2 diabetic outpatients were interviewed at the General Police Hospital in Bangkok, Thailand, between January and June 2007. Face-to-face interviews included MMAS, medication adherence visual analog scale (MA-VAS), and sociodemographic data. Medical records were reviewed for clinical data such as hemoglobin A1c (A1C) levels. Results Internal consistency reliability was moderate (Cronbach's α = 0.61), whereas the test–retest reliability of the MMAS was excellent (intraclass correlation coefficient = 0.83; p < 0.001). Concerning convergent validity, the MMAS had a high correlation with the 3-item Morisky scale (r = 0.77; p < 0.01) and a medium correlation with the MA-VAS (r = 0.57; p < 0 01). Regarding known-groups validity, a significant association between MMAS and A1C levels was found (χ2 = 6.7; p < 0.05). The sensitivity, specificity, positive predictive value, and negative predictive value of the MMAS were 51%, 64%, 71%, and 43%, respectively. Our factor analysis showed that the MMAS had 3 dimensions including forgetting to take medications, stopping medications when feeling better or worse, and the complexity of the drug regimen. Conclusions The 8-item MMAS can be a tool to aid in assessing medication adherence in diabetes. The poor sensitivity can be improved by increasing the number of the response choices and the cut-off score of the scale and by using specific words in some items. A modified Thai version of the 8-item MMAS may be needed.
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Fitilev, S. B., A. V. Vozzhaev, L. N. Saakova, I. B. Bondareva, D. A. Kliuev, and I. I. Shkrebniova. "Effect of medication adherence on the risk of cardiovascular events in outpatients with stable coronary artery disease: results of two-year monitoring." Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice, no. 1 (April 19, 2023): 26–33. http://dx.doi.org/10.37489/2588-0519-2023-1-26-33.
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Introduction. Incidence of inadequate medication adherence to secondary prevention medications among Russian coronary patients is around 50 %, but the question, how this might influence on the risk of unfavorable outcomes, still has no answer.Aim. To determine the effect of medication adherence on the risk of unfavorable clinical outcomes in outpatients with stable coronary artery disease (CAD). Methods. Prospective observational cohort study was conducted. 281 subjects with verified stable CAD were included in line with the pre-specified criteria. Medication adherence was measured by validated 8-item Morisky scale. Data on cardiovascular events were obtained over the 24-month monitoring period. Study endpoint was a composite cardiovascular event (all-cause mortality, acute myocardial infarction, unstable angina, revascularization surgery, acute heart failure, decompensation of chronic heart failure). Survival analysis by Kaplan — Meier method was performed.Results. 26.0 % of coronary outpatients had low medication adherence (below 6 points by Morisky scale). Groups of patients with satisfactory and low medication adherence were comparable by demography, medical history, and pharmacotherapy. Over the monitoring period composite cardiovascular event was registered in 115 patients (40.9 %). 46.6 % of patients from the low adherence group suffered from the composite event, 38.9 % — from the satisfactory adherence group. Time to the event was lower in the low adherence group — median 24.2 (IQR 7.5-29.2) vs. median 27.9 (IQR 17.4-34.5) months. Cumulative incidence of the composite cardiovascular event over the monitoring period was higher in the low adherence group compared to satisfactory adherence group (p=0.032; log-rank test), also when adjusted for history of cardiovascular events (p=0.033; log-rank test). Satisfactory medication adherence reduced risk of composite cardiovascular event by 37 % (HR 0.63; 95 % CI 0.42-0.94; р=0.025; Cox-regression adjusted for history of cardiovascular events).Conclusion. Coronary outpatients with satisfactory medication adherence had lower risk of cardiovascular events over the 24-month monitoring period.
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Wahab, Abrar, Md Mahabub Ul Islam, Mehbuba Mehnoor Laboni, Anisa Fatema, Abeda Saleha Renesa, and Mohammad Morshad Alam. "Medication adherence of rheumatic heart disease patients: a cross-sectional study in Bangladesh." Asian Journal of Medical and Biological Research 5, no. 3 (2019): 186–91. http://dx.doi.org/10.3329/ajmbr.v5i3.43586.
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Rheumatic heart disease (RHD) is a significant public health problem and Non-adherence to treatment is an important and often unrecognized risk factor for cardiovascular mortality. The study aimed to assess self-reported medication adherence by 8-item Morisky Medication Adherence Scale (MMAS-8) among rheumatic heart disease patients and determine the associated factors. A cross-sectional study was carried out by applying a structured interview to Rheumatic heart disease patients aged 18 or higher in a tertiary hospital in Bangladesh. Among Rheumatic heart disease patients, 63.5% showed medium adherence, 36.5% showed low adherence to medication. Walking habit (P= 0.000), exercise habit (P=0.000), smoking habit (P=0.000), and duration of RHD (P=0.005) found significantly associated with medication adherence. Multiple logistic regression analysis also revealed, don't have walking habit more than 10 minutes at a time (AOR=2.416, 95% CI: 1.212-4.816), don't having exercise habit (AOR=2.420, 95% CI: 1.206 – 4.859), don't having habit of smoking (AOR=0.392, 95% CI: 0.183 – 0.841), duration of RHD for less than 15 (AOR=4.190, 95% CI: 0.851 – 20.631) are independent predictors of adherence. Our study demonstrated medium to low medication adherence in the Morisky Medication Adherence Scale among rheumatic heart disease patients.
 Asian J. Med. Biol. Res. June 2019, 5(3): 186-191
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Abebaw, Mastewal, Anteneh Messele, Mignote Hailu, and Fisseha Zewdu. "Adherence and Associated Factors towards Antidiabetic Medication among Type II Diabetic Patients on Follow-Up at University of Gondar Hospital, Northwest Ethiopia." Advances in Nursing 2016 (January 17, 2016): 1–7. http://dx.doi.org/10.1155/2016/8579157.
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Background. The prevalence of diabetes mellitus (DM) is rising worldwide and is more in the developing countries which unfortunately are already suffering from communicable diseases. The aim of this study was to assess adherence and associated factors towards antidiabetic medication among type II diabetic patients in University of Gondar Hospital, Diabetic Clinic, Gondar, Northwest Ethiopia. Methods. Institutional based cross-sectional study was conducted. Systematic sampling technique was used. Morisky Medication Adherence Scale (MMAS) scores were used for labeling patients as adherent or nonadherent. Data were entered and analyzed using SPSS version 20. To see the association of variables logistic regression with OR and 95% CI was done. Results. A total of 288 study participants were interviewed with response rate of 100%. The level of adherence was found to be 85.1%. Factors found to be significantly associated with antidiabetic medication adherence were level of education (AOR = 14.27, 95% CI = 3.0, 67.82), duration of diabetes (AOR = 6.10, 95% CI = 2.03, 18.34), and knowledge about DM and its medications (AOR = 28.05, 95% CI = 8.96, 87.8). Conclusions and Recommendations. Large proportion of respondents in this study were found to be adherent to their antidiabetic medications. Level of education, duration of diabetes, and knowledge about DM and its medication were significantly associated with antidiabetic medication adherence of patients. Health education including adherence counseling to create awareness towards DM and its medications is mandatory.
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Khadka, Sushmita, Bikal Lamichhane, Anjana Maharjan, Manisha Bhardwaj, Anushree Jha, and Milan Bajracharya. "Adherence to Anti- Hypertensive Medications among Patients in Selected Health Facilities of Nepal." Journal of Nepal Health Research Council 19, no. 1 (2021): 83–86. http://dx.doi.org/10.33314/jnhrc.v19i1.1395.
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Background: Hypertension is a non-communicable disease and one of the most prominent modifiable risk factors for cardiovascular diseases. 7.6 million premature deaths are attributed to high blood pressure around the world. Better adherence with antihypertensive medications improves quality and length of life. This research focuses on the extent of adherence towards prescribed antihypertensive treatment, and identify factors influencing non-adherence.Methods: Descriptive cross-sectional study design was undertaken in various health care centers (2 primary health care center and 3 hospitals) of Nepal. A total of 348 individuals (age above 30) who suffered from hypertension visiting health institutes were included in the study. Adherence was calculated using Morisky Medication Adherence scale.Results: Adherence level to the antihypertensive medication as per the morisky adherence scale, 38.8% had medium level of adherence, 37.4% had a low adherence level, and 23.9% had a high adherence level among 348 participants. From the total participants, 89 admitted to be irregular in medication use. 56% of them claimed to do so because of forgetfulness, 12.4 % because of consistent exercise and low-salt diet, 10.1% due to the lack of affordability.Conclusions: Our study had concluded that the majority of participants had medium to low levels of adherence to anti-hypertensive drugs. Forgetfulness was major cause for irregular medication. Patient education and counseling, family support also seem to be important for proper adherence to drugs. Thus, health care providers should allocate ample time in educating, counseling clients and family.Keywords: Adherence; hypertension; medication; patients
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Zyryanov, Sergey K., Sergey B. Fitilev, Alexander V. Vozzhaev, et al. "Medication adherence in patients with stable coronary artery disease in primary care." Research Results in Pharmacology 6, no. 2 (2020): 97–103. http://dx.doi.org/10.3897/rrpharmacology.6.54130.
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Introduction: Lack of research targeting non-adherence to cardiovascular medications in Russia prevents from developing effective interventions to improve adherence. The aim was to study medication adherence in patients with stable coronary artery disease in primary care. Material and methods: The study was conducted in a primary care setting of Moscow. Demography, medical history, pharmacotherapy data were obtained retrospectively from 386 coronary patients’ medical records. Medication adherence was measured by 8-item Morisky Medication Adherence Scale (MMAS-8). A statistical analysis was performed using SPSS Statistics V16.0. Results and discussion: According to the results from MMAS-8, 188 (48.7%) coronary patients had high medication adherence, 135 (35.0%) – moderate, and 63 (16.3%) – low. By the dichotomous interpretation: 48.7% (n = 188) – were adherent, 51.3% (n = 198) – were non-adherent. These groups were similar in gender distribution, age, and medical history profile (p &gt; 0.1 for all variables). Smokers prevailed in the non-adherent group (13.6 vs. 5.3%; p = 0.009). Both groups were equally prescribed beta-blockers, antiplatelets, and statins (p &gt; 0.1 for all). Use of fixed dose combinations (11.7 vs. 5.6%; p = 0.048) and the number of pills taken (mean 5.64 ± 1.52 vs. 5.99 ± 1.62; p = 0.029) were associated with better adherence. Higher values of total cholesterol (mean 5.2 ± 1.4 vs. 4.7 ± 1.2 mmol/L; p &lt; 0.001) and low-density lipoprotein cholesterol (mean 2.9 ± 1.2 vs. 2.4 ± 0.9 mmol/L; p &lt; 0.001) were revealed in non-adherents. Subjects with suboptimal adherence visited general practitioners more frequently (median 5 vs. 3 visits; p = 0,003). Conclusion: Medication non-adherence in coronary outpatients exceeded 50%. High adherence was associated with more frequent use of fixed dose combinations and fewer pills taken by patient. Smoking and poorer control of blood lipids prevailed in non-adherents, who also caused higher load on general practitioners.
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Philip, Aneena Annu, Manisha Mohanan, Merine Shine, Sherin Sara Benny, and Poornima Ashok. "Assessment of Medication Adherence Barriers in COPD Patients in A Secondary Care Teaching Hospital." Journal of Drug Delivery and Therapeutics 10, no. 2-s (2020): 80–85. http://dx.doi.org/10.22270/jddt.v10i2-s.4013.
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Background: COPD is characterised by persistent airway obstruction in which better clinical outcome can be attained by appropriate management of disease. Adherence to COPD medication is poorly understood due to chronic nature of the disease. It is crucial to identify the barriers of non-adherence to build up and execute policies and interventions to upgrade medication adherence. Objective: To identify the predisposing barriers of medication adherence and to find the association between medication adherence and variables. Methods: A descriptive analytical study was conducted and data was collected from COPD outpatients. The Morisky Medication Adherence Scale was used to measure adherence and self-assessed questionnaire was employed to identify the predictors of poor adherence. Chi square test was carried out to find the relationship between medication adherence and variables such as age, gender, literacy, socioeconomic class, polypharmacy, delivery device and climate. Results: A total of 403 patients were involved in the study where 68% reported lower adherence. The most common adherence barriers found were forgetfulness (88%), intentional stoppage of medicines when symptoms improve (83%) and negligence towards medication (82%).A significant association was found between gender, literacy, socioeconomic class, polypharmacy, delivery device and climate. Conclusion: Adherence to medication regimen in COPD patients is poor, even though it is a preventable and a treatable disease. Well-structured education, training, counseling is required to overcome medication adherence particularly among illiterate and low socioeconomic class patients. The combined interventions should be used such as video clips demonstrations of inhaler technique should be given.
 Keywords: COPD, Morisky medication adherence scale, Chi square test.
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Saad, Anwar Habeeb, Ihsan Rabeea, and Haider Salih. "Adherence and Beliefs to Adjuvant Hormonal Therapy in Patients with Breast Cancer: A Cross-Sectional Study (Conference Paper) #." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 30, Suppl. (2022): 31–39. http://dx.doi.org/10.31351/vol30isssuppl.pp31-39.
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Breast cancer is the most common cancer among women over the world. To reducing reoccurrence and mortality rates, adjuvant hormonal therapy (AHT) is used for a long period. The major barrier to the effectiveness of the treatment is adherence. Adherence to medicines among patients is challenging. Patient beliefs in medications can be positively or negatively correlated to adherence. Objectives: To investigate the extent of adherence and factors affecting adherence, as well as to investigate the association between beliefs and adherence in women with breast cancer taking AHT. Method: A cross-sectional study included 124 Iraqi women with breast cancer recruited from Middle Euphrates Cancer Center. Morisky medication adherence scale (MMAS) and beliefs about medication questionnaires (BMQ) are used to assess adherence and beliefs respectively. Result: 25% of women were fully adherent (MMAS = 8). 83.06% of all women developed side effects from medications received. Side effects and unemployed women were significantly associated with non-adherence. Additionally, there is no significant association between beliefs in medications and adherence. conclusion The enormous percent of poor adherence caused by side effects suggests the need for interventions by educating patients about the importance of their treatment and how to overcome side effects.
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AlHewiti, Abdullah. "Adherence to Long-Term Therapies and Beliefs about Medications." International Journal of Family Medicine 2014 (February 13, 2014): 1–8. http://dx.doi.org/10.1155/2014/479596.
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Objectives. To assess adherence to long-term medications among patients in family medicine clinics and to evaluate relationship between adherence, beliefs about medications, medication information adequacy, and other factors. Methods. Interviewer assisted survey was conducted to assess adherence using the 8-item Morisky Medication Adherence Scale (MMAS-8), beliefs about medications using beliefs about medicine questionnaire (BMQ), and the patients’ perception of medication information adequacy. Results. Of the 408 participants, 56.9% reported low adherence. Pearson’s bivariate correlation showed positive association between MMAS-8 score and BMQ-specific necessity (r=0.526 P<0.001) and the perceived information adequacy (r=0.568 P<0.001), and there was negative association between adherence score and BMQ specific concerns, general overuse, and harm (r=-0.647, -0.466, and -0.663, resp.) (P<0.001). Multivariable analysis revealed that age, number of medications, number of medical conditions, specific necessity and concerns beliefs, general harm beliefs, and perceived adequacy of medication information were independent predictor of adherence. Furthermore, specific beliefs explain 27.7% of the variance in adherence, while medication information adequacy explains 32.3% of the variance in adherence. Conclusion. The prevalence of low adherence among patients on long-term medications is high and it is related to negative beliefs about medications and to inadequate information given to patients about their medications.
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Galal, Iman H., Yasser M. Mohammad, Abeer A. Nada, and Yosra E. Mohran. "Medication adherence and treatment satisfaction in some Egyptian patients with chronic obstructive pulmonary disease and bronchial asthma." Egyptian Journal of Bronchology 12, no. 1 (2018): 33–40. http://dx.doi.org/10.4103/ejb.ejb_56_17.
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Abstract Background The degree of effectiveness in the management of asthma and chronic obstructive pulmonary disease (COPD) entails proper treatment adherence and satisfaction. In this study, medication adherence and treatment satisfaction were assessed among some Egyptian patients with asthma and COPD. Materials and methods Consecutive asthma and COPD patients were recruited from the outpatient clinic or inpatients admitted to the Chest Department at Ain Shams University Hospital, Abbassia, and Qena Chest Hospitals. Self-reported medication adherence and treatment satisfaction were tested using the Arabic versions of the eight-item Morisky Medication Adherence Scale and Treatment Satisfaction Questionnaire for Medication (TSQM 1.4), respectively. Results Totally, 474 asthmatic patients (mean: 34.41 years, 61.2% male and 38.8% female) and 509 COPD patients (mean: 60.39 years, 91.7% male and 8.3% female) were included. According to eight-item Morisky Medication Adherence Scale, mean adherence was 4.55±2.01 and 3.88 ±1.63 in asthma and COPD, respectively, with no significant difference. In asthma and COPD, low adherence was found in 71.7 and 79.4%, medium adherence in 19.8 and 13.6%, and high adherence in 8.4 and 7.1%, respectively. There was a significant difference in all domains of TSQM between asthma and COPD, with more effectiveness, convenience, and global satisfaction but less side effects among asthma patients compared with COPD. There was a significant correlation in asthmatic patients between adherence and all domains of TSQM, whereas in COPD only side effects and convenience correlated significantly with adherence. In COPD, adherence was better in male smokers, with low smoking index, living in urban areas, having severe small airway obstruction, and treated by pulmonologists. In asthma, adherence was mainly affected by treatment satisfaction. Conclusion Most of the asthma and COPD patients were nonadherent to their medications. Asthma patients were more satisfied with treatment compared with COPD patients.
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Somu, Lavakumar, and Jacob Jesurun Rs. "A STUDY ON THE LEVEL OF DRUG COMPLIANCE AMONG THE OUTPATIENTS WHO ARE ON A LONG-TERM DRUG THERAPY IN A TERTIARY CARE TEACHING HOSPITAL AT KANCHEEPURAM DISTRICT IN TAMILNADU." Asian Journal of Pharmaceutical and Clinical Research 10, no. 3 (2017): 174. http://dx.doi.org/10.22159/ajpcr.2017.v10i3.15974.
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ABSTRACTObjectives: To evaluate the drug compliance level among the patients attending the outpatient department of Shri Sathya Sai Medical College Hospitalusing Morisky 8-item drug compliance questionnaire and to determine the factors which hinder them from adhering to physician’s prescription.Methods: 100 patients who were on long-term drug treatment on outpatient basis were selected. Following that, Morisky 8-item drug compliancequestionnaire, a self-reported scale of medication adherence was used. Along with the mentioned questions, a few questions to assess factors causingnoncompliancy and their knowledge on drug compliance were included. Data were collected and based on the scale, the level of compliance, i.e., low,medium or high was estimated. Patients found noncompliant, factors hindering them from being noncompliant were assessed.Results: Among the 100 patients, 33% belonged to low adherence group, 44% to medium adherence group, and 23% to high adherence group.Patients belonging to low and medium adherence group were segregated and their individual questionnaire was assessed and reason for beingnoncompliant analyzed. The majority of the low adherence group said that they discontinue treatment once they feel that their symptoms were undercontrol.Conclusion: Drug noncompliance is an important factor for treatment failure. The importance of medication adherence was re-emphasized to thosepatients who belonged to low/medium adherence group.Keywords: Morisky, Drug compliance, Shri Sathya Sai, Low adherence.
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Allela, Omer, Hishyar Mohammed Salih, and Ahmed Idris Haji. "Adherence to medication and glucose control in diabetic patients in Duhok, Iraq." Pharmacia 69, no. (3) (2022): 673–79. https://doi.org/10.3897/pharmacia.69.e86649.
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Background: Diabetes mellitus is a chronic, progressive disorder that causes a variety of health problems. Adherence to medication is a major factor in the treatment outcome. The goal of this study is to translate and test the psychometric features of the Kurdish version of the Morisky Medication Adherence Scale (MMAS-8) among type 2 diabetic patients. Methods: The research used a cross-sectional approach. The researchers looked at a convenient sample of diabetic Kurdish individuals. MMAS-8 was translated into Kurdish using a normal "forward–backward" technique. It was then tested on 307 type 2 diabetic outpatients in a convenience sample. Internal consistency was checked for reliability. Convergent and known group validity were used to confirm validity. For the authentic statistical analysis, the Statistical Package for Social Sciences (SPSS) version 20 was used. Results: According to MMAS-8, 20 patients (6.5%) had a high adherence rate, 66 (21.5%) had a medium adherence rate, and 221 (72%) had a low adherence rate. There was no significant link between adherence score and gender (P = 0.055), illness duration (P = 0.251), or educational level (P = 0.12). There was a significant connection between adherence and HBA1C (P 0.001). Conclusion: The results of this validation study show that the Kurdish version of the MMAS-8 is a reliable and valid measure of medication adherence that may now be used. non-adherent. Developing patients' treatment adherence will improve treatment managements and control.
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K.M, Vivekanandan, Siva R, Smilelin Raju, and Saranya G. "A Pilot Study Evaluating Medication Adherence in Geriatric Patients with Chronic Conditions." Asian Journal of Advanced Research and Reports 19, no. 1 (2025): 29–36. https://doi.org/10.9734/ajarr/2025/v19i1859.
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Introduction: More established grown-ups are more inclined to ongoing circumstances and intermittent ailment like hypertension, diabetes mellitus, respiratory messes and so on which might require persistent prescription with different medications. Unfortunate consistency in this age bunch represents medicine wastage with the inflated cost of medical care and significant deterioration of the sickness with disability of death. A large portion of the human and financial expenses related to non-adherence can be tried not by further developing prescription adherence. Typically, geriatric patients have different co-morbidities, which can antagonistically influence drug consistence. Our review recognizes different reasons liable for low adherence. Aim: To assess the level of medication compliance in the geriatric patients with chronic conditions and also analyze the reason behind the non-adherence. Materials and methods: The study subjects were assessed by using 8 structured questionnaires as per modified morisky medication adherence scale(MMAS). Results: A total of 88 subjects of geriatric patients with chronic conditions were assessed for the level of compliance for long term medications. The compliance level was assessed by interviewing patients with 8 item structured questionnaires as per Modified Morisky Medication Adherence Scale (MMAS). The level of compliance was high in 34 and moderate in 39 and low in 15 of the study subjects. Conclusion: To further develop drug adherence it is fundamental to recognize the purposes for the non-adherence like confounded systems, obliviousness about the sickness and inconveniences, physical and financial problems, forgetfulness, accessibility issues and absence of section of land providers and so on. Geriatric patients particularly tend to quit taking drugs by their own this can make it hard to anticipate improvement in the adherence. So, medication consistency is a vital element which increments helpful result.
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AlGhailani, Aaisha, Eman Alyaseen, Amna AlBalushi, et al. "Factors affecting adherence to hypertension medications in hypertensive patients attending to primary health care units in Bahrain." Journal of Family Medicine and Primary Care 14, no. 6 (2025): 2336–45. https://doi.org/10.4103/jfmpc.jfmpc_1116_24.
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ABSTRACT Background: Adherence to antihypertensive medications is crucial for controlling hypertension and reducing cardiovascular disease risk. This study aimed to assess adherence and influencing factors among hypertensive patients in Bahrain. Methods: A cross-sectional study recruited 209 adults with diagnosed hypertension attending primary healthcare centers. Sociodemographic data, medical history, medication adherence using the Morisky Medication Adherence Scale (MMAS-8), and attitudes towards hypertension medications were collected. Results: Over half (54.1%) reported controlled blood pressure, and 80.4% reported good adherence by MMAS-8. Being younger, single, not regularly checking blood pressure, and lacking a family history of hypertension were associated with poorer adherence. Negative perceptions regarding seriousness of hypertension and the susceptibility to complications together with the necessity or effectiveness of medication were all linked to poorer adherence. Conclusions: This study provides insights into factors influencing medication adherence among hypertensive patients in Bahrain. While adherence rates appear high by self-report, further research using diverse methods is needed. Tailored education addressing concerns and emphasizing long-term benefits of medication adherence is recommended. Promoting regular blood pressure monitoring and simplifying medication regimens could also improve outcomes.
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Shareinia, Habib, Leila Sadeghmoghadam, Mohammad Reza Mokhtarzadeh, Seyede Maryam Zahrayi, Nemat Jafari, and Reza Noori. "Relationship Between Polypharmacy and Medication Adherence in the Hypertensive Elderly Patients." Disease and Diagnosis 9, no. 4 (2020): 153–57. http://dx.doi.org/10.34172/ddj.2020.05.
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Background: Proper adherence to the medication regimen in hypertensive elderly patients is important. This study aimed to investigate the relationship between polypharmacy with adherence to the medication regimen in hypertensive elderly patients. Materials and Methods: Using stratified random sampling method, the present descriptive-analytical study was performed on 384 hypertensive elderly patients in Gonabad, Iran in 2016. The study population included males and females aged over 60 years who were covered by Gonabad urban and rural community health centers. Data were collected using demographic questionnaire and the eight-item Morisky Medication Adherence Scale (MMAS-8). Results: The mean daily medications in participants was 6±2.43, and a high medication adherence was observed among 36.7% of the subjects. Chi-square test showed a significant relationship between polypharmacy and medication adherence (P = 0.006). Conclusion: Physicians and nurses can play an important role in preventing the risks of polypharmacy, as well as non-adherence to medication regimen by educating the hypertensive elderly patients or their caregivers.
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Kapoor, Jyotsna, Narendra Agrawal, Rayaz Ahmad, Sanjeev Kumar Sharma, Anshul Gupta, and Dinesh Bhurani. "FACTORS INFLUENCING ADHERENCE TO IMATINIB IN INDIAN CHRONIC MYELOID LEUKEMIA PATIENTS: A CROSS-SECTIONAL STUDY." Mediterranean Journal of Hematology and Infectious Diseases 7 (February 12, 2015): e2015013. http://dx.doi.org/10.4084/mjhid.2015.013.
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Adherence to imatinib(IM) is of utmost importance in patients with chronic myeloid leukemia(CML) to maximise treatment effectiveness. The main objective is to measure adherence to IM & to evaluate individual patient characteristics, personal, treatment related & psychological factors influencing adherence behaviour. Hundred patients receiving IM were analysed for adherence behaviour using 9 item Morisky Medication Adherence Scale (9-MMAS) . Various factors were assessed for their impact on adherence behaviour. These factors were age, gender, duration of treatment, frequency & dosing of treatment, use of tobacco & alcohol, educational qualification,employment status,monthly income, side effects, financial assistance in treatment, social support, knowledge about medicine & disease, concomitant drug burden, polypharmacy, physician patient interaction, patient educational sessions & prevalence of depression. Seventy five percent of patients were found to be adherent. On univariate analysis, prevalence of depression (p<0.000001), moderate severe depression (p<0.000001), concomitant drug burden (p=0.036) & monthly income (p=0.015) were found to be significantly influencing adherence. The final multivariate model retained prevalence of depression with OR= 10.367 (95% CI, 3.112- 34.538) as independent predictor of adherence to therapy. This study suggests that identification & treatment of depression among CML patients may further enhance adherence to IM therapy.Keywords: Chronic Myeloid Leukemia, Adherence, Imatinib, Nine Item Morisky Medication Adherence Scale, Patient Health Questionnaire -9.
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Liu, Zitian, Yuning Zhang, Pingping Liu, et al. "Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma." Journal of Ophthalmology 2022 (December 31, 2022): 1–13. http://dx.doi.org/10.1155/2022/6389822.
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Purpose. To investigate the medication adherence among caregivers of preschool children with pediatric glaucoma and to elucidate common barriers leading to poor adherence. Methods. A cross-sectional study. Caregivers of preschool children with pediatric glaucoma completed a questionnaire on demographic information of caregivers, demographic and disease characteristics of children, caregivers-reported medication adherence (by an adapted Morisky Adherence Scale), and possible 13 barriers. Results. Overall 132 questionnaires were considered valid. Thirty-six percent of all reported poor medication adherence. Caregivers’ age and self-evaluated knowledge about pediatric glaucoma showed a significant difference between the adherent and nonadherent groups ( P < 0.05 ). Nineteen percent of all reported only one barrier as important, 65% cited multiple barriers, and 16% cited no barriers. Anxiety and depression were cited as important by most caregivers in both groups. Univariate logistic regression analysis demonstrated that difficulty with the acquisition of medications (OR, 2.5; 95% CI, 1.1–5.7; P = 0.025 ), difficulty with medication schedule (OR, 2.3; 95% CI, 1.0–5.0; P = 0.043 ), and high expenses for medications (OR, 4.8; 95% CI, 1.4–15.9; P = 0.011 ) were significantly associated with higher odds of poor adherence. Conclusions. Over one-third of caregivers of preschool children with pediatric glaucoma were in poor medication adherence. Nearly two-thirds of caregivers cited multiple barriers simultaneously as important hindrances to medication usage. Anxiety and depression, difficulty with the acquisition of medications, difficulty with the medication schedule, and high expenses for medications were prominent barriers. Individualized solutions should be provided according to reported barriers by each caregiver and the other most common barriers.
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Olaniran, GO, BA Akodu, AA Olaniran, JO Bamidele, AO Ogunyemi, and OO Idowu. "Medication Adherence and Perceived Family Support Among Elderly Patients with Hypertension Attending a Specialty Clinic in Lagos, Nigeria." Annals of Health Research 9, no. 1 (2023): 30–42. http://dx.doi.org/10.30442/ahr.0901-04-188.
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Background: Hypertension and medication adherence are global public health challenges, with elderly patients suffering the most because they frequently have multiple co-morbidities. Objective: To evaluate the level of medication adherence and perceived family support among Nigerian elderly patients with hypertension. Methods: A descriptive, cross-sectional study among 293 consecutively consenting elderly hypertensive patients using an interviewer-administered, semi-structured questionnaire. The Modified Morisky Adherence Scale (MMAS-8) and Perceived Social Support-Family Scale (PSS-Fa) tools were used to assess medication adherence and perceived family support, respectively. Results: The mean age of respondents was 69.5±6.4 years. Medication adherence was good, moderate and poor among 14.3%, 68.6%, and 17.1% of the respondents respectively. Difficulty remembering to take medications was the primary reason for non-adherence in 73.7% of cases. Good adherence to medication was significantly associated with male gender (p = 0.046), living with grandchildren (p˂0.001), having other sources of income (p = 0.026) and receiving treatment for comorbid illnesses (p = 0.025). A higher proportion of the respondents (94.9%) had strong perceived family support, which lacked statistical significance regarding good medication adherence. (p = 0.739). Conclusion: This study found medication adherence low, despite most participants' strong family support. Forgetfulness and financial constraints were the primary reasons for poor medication adherence. Although family support is highly recommended and beneficial for medication adherence, other comorbid and social factors should be considered.
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P., Thungamithirai, Manjusha A. Dhoble, Uday W. Narlawar, Shilpa S. R., Shubhangi S. Bembade, and Ajaya Krishnan P. "A community based cross-sectional study on compliance and barriers of iron and folic acid consumption among postnatal mothers of 0-6 weeks in an urban area from central India." International Journal Of Community Medicine And Public Health 12, no. 1 (2024): 286–91. https://doi.org/10.18203/2394-6040.ijcmph20244033.
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Background: Iron deficiency anemia is becoming prevalent in postpartum women who are not aware about the importance of iron and folic acid (IFA) consumption. There might be many barriers which ultimately result in noncompliance. Thus, this study aimed in assessing compliance and barriers of IFA consumption among postnatal women. Methods: A cross-sectional study was conducted in 175 postnatal mothers in an urban area from Nagpur. A semi-structured questionnaire was used to assess the compliance and barriers to IFA consumption. Adherence level was assessed using the Morisky medication adherence scale. Results: The study found that 71% of the study participants were compliant to IFA consumption. Among the non-adherent participants, the main barrier found was the knowledge barrier and the prevailing side effects. According to the Morisky medication adherence scale, the majority exhibited a strong adherence. Conclusions: About three fourth of the participants were compliant to IFA consumption. Compliance was found significant among those who were primigravida, higher monthly income, received health education regarding IFA and intake of IFA during ANC period. Considering the barriers observed in the study the major recommendation will be to improve the palatability and enhance the health education.
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Ahdiyah, Nike Nur, Medi Andriani, and Lili Andriani. "Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis Pada Pasien TB Paru Dewasa Di Puskesmas Putri Ayu." Lumbung Farmasi: Jurnal Ilmu Kefarmasian 3, no. 1 (2022): 23. http://dx.doi.org/10.31764/lf.v3i1.6817.
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ABSTRAKPenyakit Turberkulosis adalah suatu penyakit kronik menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Salah satu faktor yang menyebabkan tingginya angka kegagalan pengobatan penderita TB paru adalah tingkat kepatuhan yang masih rendah. Kepatuhan adalah tingkat perilaku penderita dalam mengambil suatu tindakan pengobatan, misalnya dalam menentukan kebiasaan hidup sehat dan ketetapan berobat. Kepatuhan terhadap pengobatan panjang Tuberkulosis merupakan kunci dalam pengendalian Tuberkulosis. Penelitian ini bertujuan untuk mengetahui tingkat kepatuhan pengunaan obat anti tuberkulosis pada pasien TB paru di Puskesmas Putri Ayu. Penelitian ini termasuk penelitian observasional dengan rancangan cross-sectional. Pengambilam data mengunakan kuisoner yang di buat berdasarkan MMAS-8 (Morisky Medication Adherence Scale) dan wawancara. Hasil penelitian menunjukan bahwa tingkat kepatuhan pengunaan obat anti tuberkulosis sebanyak 26 responden (76,47%) memiliki kepatuhan tinggi, 7 responden (20,58%) memiliki kepatuhan sedang, dan 1 responden (2,95%) memiliki kepatuhan rendah jadi berada pada tingkat kepatuhan pasien tuberkulosis paru di Puskesmas Putri Ayu kategori kepatuhan tinggi dan untuk uji chi squre hanya pengahasilan yang memiliki hubungan antar tingkat kepatuhan.Kata kunci : Tuberkulosis; Obat Anti Tuberkulosis; Tingkat Kepatuhan; MMAS-8 (Morisky Medication Adherence Scale).ABSTRACTTurberculosis is a chronic infectious disease caused by the bacterium Mycobacterium tuberculosis. One of the factors that causes the high rate of treatment failure for pulmonary TB patients is the low level of adherence. Compliance is the level of patient behavior in taking a treatment action, for example in determining healthy living habits and treatment decisions. Adherence to long-term tuberculosis treatment is the key in controlling tuberculosis. This study aims to determine the level of adherence to the use of anti tuberculosis drugs in pulmonary TB patients at Putri Ayu Health Center. This study is a observational study with a cross-sectional design. Collecting data using a questionnaire that was made based on MMAS-8 (Morisky Medication Adherence Scale) and interviews. The results showed that the level of adherence to the use of anti tuberculosis drugs as many as 26 respondents (76.47%) had high adherence, 7 respondents (20.58%) had moderate adherence, and 1 respondent (2.95%) had low adherence so they were at the level of compliance of pulmonary tuberculosis patients at the Putri Ayu Health Center in the high compliance category and for the chi squre test only income has a relationship between compliance levels.Keywords : Tuberculosis; anti-tuberculosis drugs; adherence level; MMAS-8 (Morisky Medication Adherence Scale).
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Jarab, Anan S., Tareq L. Mukattash, and Hayat Hilan. "Medication Non-adherence in Patients with Osteoporosis: Implications for Clinical Pharmacists and Osteoporosis Care Providers." Current Clinical Pharmacology 15, no. 3 (2020): 243–50. http://dx.doi.org/10.2174/1574884715666200116104754.
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Background : Poor adherence to the prescribed therapy leads to low bone mineral density and enhance the development of osteoporosis complications and unnecessary hospitalization. Objective : To explore factors associated with medication non-adherence in patients with osteoporosis. Findings would help guide the development of future pharmaceutical care interventions aim at improving health outcomes for patients with osteoporosis. Methods: The study was conducted at an outpatient osteoporosis clinic at the Royal Medical Services Hospital. Variables including socio-demographics and medical factors were collected using medical records and custom-designed questionnaire. Medication adherence was assessed using the validated 4-item Morisky Medication Adherence Scale. Logistic regression was performed to develop a model with variables that best predicted medication non-adherence in patients with osteoporosis in Jordan. Results : A total of 296 patients participated in the study. Most of the study participants (72.3%) were found non-adherent. Patients were found less likely to adhere to the prescribed medications with each unit increase in the number of prescribed medications (OR = 2.503, CI = 1.103-5.680) and if they did not have a trust in the efficacy of the medications (OR = 5.544, CI = 0.990-31.058). Conclusion: Medication adherence for patients with osteoporosis has considered scope for improvement in Jordan. Simplifying dosage regimen in addition to taking patients’ preferences when selecting the medications should be taken into account in future interventions designed to improve health outcomes for patients with osteoporosis.
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Alonso-CastroAlan, Angel Josabad, Alan Joel Ruiz-Padilla, Eleazar Carranza, et al. "Concomitant use of allopathic medicine and herbal products for weight-loss among people with overweight or obesity from Central Mexico." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 22, no. 2 (2023): 194–203. http://dx.doi.org/10.37360/blacpma.23.22.2.14.
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This study evaluated the prevalence of concomitant use of herbal products for weight loss (HPWL) and allopathic medicine. Factors associated with the prevalence, adverse reactions, and the alteration of medication adherence with the concomitant use of HPWL alone and in combination with allopathic medicine, were assessed. The study was descriptive and cross-sectional using a questionnaire conducted among people with overweight or obesity (n=662) from five cities of Central Mexico. Adherence to medications was measured using the Morisky Medication Adherence Scale. The prevalence of adverse reactions induced by the concomitant use of HPWL, and allopathic medicine was 25.3%. The use of HPWL affected medication adherence by 68%. There is a high prevalence (45.2%) of concomitant use of HPWL and allopathic medicine in people with overweight or obesity in Central Mexico. The concomitant use of HPWL and allopathic medicine induces adverse reactions, mainly gastrointestinal, and thus, medication adherence is affected.
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Okoro, Roland Nnaemeka, Ibrahim Ummate, John David Ohieku, Sani Ibn Yakubu, Maxwell Ogochukwu Adibe, and Mathew Jegbefume Okonta. "Evaluation of medication adherence and predictors of sub-optimal adherence among pre-dialysis patients with chronic kidney disease." Medicine Access @ Point of Care 4 (January 2020): 239920262095408. http://dx.doi.org/10.1177/2399202620954089.
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Background: Multiple medications are required to effectively manage chronic kidney disease (CKD) and associated complications, posing the risk of poor medication adherence. Objectives: To measure medication adherence levels and to investigate the potential predictors of sub-optimal medication adherence in pre-dialysis patients with CKD. Methods: A prospective study was conducted in the medical and nephrology outpatients’ clinics in Maiduguri. Non-dialysis patients with CKD stages 1–4 aged 18 years and above were recruited through their physicians. The level of medication adherence was determined using Morisky Medication Adherence Scale. Descriptive statistics were used to summarize patients’ background characteristics. Multivariate binary logistic regression analyses were performed to investigate the significantly potential predictors of sub-optimal medication adherence at a p < 0.05. Results: There were 107 participants (48.6%) who had high medication adherence, while 97 (44.1%), and 16 (7.3%) of them had moderate adherence, and low adherence, respectively. The univariate analysis revealed that medication adherence level differed significantly with the number of medications taken daily by patients ( p < 0.05). Multivariate logistic regression analyses did not reveal a significant independent predictor of sub-optimal medication adherence. Conclusion: A majority of the participants reported sub-optimal medication adherence. The independent variables considered did not significantly predict sub-optimal medication adherence in the study population. Nevertheless, the study findings highlight the importance of clinical pharmacists’ CKD management supportive care to help improve medication adherence.
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Nada, S. Almakhlafi, E. Alhumoud Alanoud, N. Alsubaie Alanoud, M. Alhalwan Shatha, and A. Albyyaai Hana. "Factor Influencing Medication Adherence Among Patients with Chronic Diseases: A Cross Sectional Study." International Journal of Innovative Research in Engineering & Multidisciplinary Physical Sciences 10, no. 3 (2022): 1–6. https://doi.org/10.5281/zenodo.12705816.
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Objective: This study aimed to investigate the factors influencing medication adherence among patients with chronic diseases using a mixed-methods approach. Methods: A cross-sectional study was conducted over four months from January to April 2022 with 100 patients from Tertiary hospital. Quantitative data were collected using the Morisky Medication Adherence Scale (MMAS-8), and qualitative data were gathered through in-depth interviews. Quantitative data were analyzed using descriptive statistics, correlation, and regression analyses. Thematic analysis was employed for qualitative data. Results: The mean MMAS-8 score was 5.8, indicating moderate adherence. Health literacy was positively correlated with medication adherence (r = 0.42, p < 0.001), while treatment regimen complexity was negatively correlated (r = -0.36, p < 0.01). Qualitative findings identified four main themes: understanding and managing medications, beliefs and attitudes towards medications, healthcare access, and social support. Patients with higher health literacy, simplified regimens, positive attitudes towards medications, better healthcare access, and strong social support networks reported better adherence. Conclusion: Medication adherence among patients with chronic diseases is influenced by health literacy, treatment regimen complexity, patient beliefs, healthcare access, and social support. Interventions targeting these factors could enhance adherence and improve patient outcomes.
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Angadi, Navinkumar, and Shubha DB. "Social Support and Medication Adherence Among People with Type 2 Diabetes Mellitus in Central Karnataka, India." National Journal of Community Medicine 14, no. 12 (2023): 834–41. http://dx.doi.org/10.55489/njcm.141220233301.
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Background: Social support is crucial to improving the health of people with type 2 diabetes mellitus through medication adherence. Objectives: 1. To assess the social support and medication adherence among people with Type 2 diabetes mellitus. 2. To study the factors associated with social support and medication adherence among people with Type 2 diabetes mellitus. Methodology: This community-based study was undertaken among 150 people with type 2 diabetes mellitus. Social support was assessed using standard, validated Multidimensional Scale of Perceived Social Support. Medication adherence was assessed using standard, validated 8-item Morisky adherence scale. Results: Mean age of study participants was 57.42±11.07 years. In the present study 87 (58%) had high social support followed by moderate support 63 (42%). In the present study majority of study participants 83 (55%) had moderate medication adherence followed by low medication adherence 67 (45%). Conclusions: Social support plays an important role in promoting medication adherence among diabetes patients.
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Huyen, Nguyen Thi Thu, and Dinh Manh Hai. "Medications adherence in patients with osteoporosis after vertebroplasty or kyphoplasty at Hanoi Medical University Hospital." Tạp chí Nghiên cứu Y học 154, no. 6 (2022): 44–51. http://dx.doi.org/10.52852/tcncyh.v154i6.782.
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Poor adherence to medication therapy is currently one of the most critical obstacles facing osteoporosis care and it is one of the main barriers for optimal therapeutic osteoporosis management, especially after surgical intervention. This paper presents medication adherence and explores factors associated with medications non-adherence in patients with osteoporosis after vertebroplasty or kyphoplasty. This is a retrospective case series included osteoporosis patients underwent vertebroplasty or kyphoplasty at Hanoi Medical University Hospital in 2019. Medication adherence was assessed using the validated Osteoporosis specific Morisky Medication Adherence Scale. A total of 42 patients participated in the study. Level of osteoporosis medication adherence decreased gradually with time of using medication: high adherence level after 1 month with OS-MMAS score was 8. Mean score of medium and low adherence after 3 months and 6 months were 6.64 ± 1.19 and 4.64 ± 2.18, respectively . 57.14% of participants had low adherence (6 months). 73.81% patients forgot to take medication. The associated factors of medication adherence are residence area, occupation, education level, number of medication used, frequency of osteoporosis medication, failure to take medication and side effects. The current study reveals a low level of medication adherence and sheds the light on different causes of medication non-adherence among patients with osteoporosis after vertebroplasty or kyphoplasty. Identifying barriers for medication non-adherence is an important initial step for developing effective clinical pharmacy interventions for patients with osteoporosis.
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Shakya, Pushpanjali, Archana Shrestha, Biraj Man Karmacharya, Donald E. Morisky, and Bård Eirik Kulseng. "Factors Associated with Medication Adherence among Patients with Type 2 Diabetes Mellitus: A Hospital-Based Cross-Sectional Study in Nepal." International Journal of Environmental Research and Public Health 20, no. 2 (2023): 1537. http://dx.doi.org/10.3390/ijerph20021537.
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As diabetes increases globally, high mortality increases due to complications of uncontrolled sugar. Medication adherence is important to control blood sugar and prevent its complications. Objective of the study was to identify factors associated with medication adherence among type 2 diabetes patients. A cross-sectional study was conducted among 343 patients visiting Dhulikhel Hospital, Nepal, for their fasting blood sugar test from September to December 2016. Inclusion criteria: patients with type 2 diabetes, under diabetes medication for past three months (minimum), age ≥ 18 years. The outcome of the study was medication adherence measured using the eight-item Morisky medication adherence scale (MMAS-8) (© 2006 Donald E. Morisky). Multivariate logistic regression was used for the analysis. Results showed that 61% of respondents had high medication adherence; adherence was positively associated with formal education [AOR: 2.43 (95% CI: 1.34, 4.39)] and attendance at diabetes counseling [AOR: 1.76 (95% CI: 1.02, 3.04)] after adjusting for age, occupation, medicine intake duration and diabetes medicine types. The study concluded that formal education and attendance at diabetes counseling positively affected patients’ adherence to medicine. We encourage healthcare institutions to provide counseling services to all the patients with type 2 diabetes and focus more on those who are less educated.
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Shane, Q. Benitez, Y. Cenizan Florelyn, B. Torrion Melissa, E. Almonguera Judith, and T. Ederio Nikko. "Factors Affecting Medication Adherence among Elderly People with Chronic Illness in Surigao City." International Journal of Current Science Research and Review 07, no. 05 (2024): 3378–92. https://doi.org/10.5281/zenodo.11388892.
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Abstract : A descriptive quantitative study in Surigao City, Philippines, investigated the factors affecting medication adherence in elderly individuals with chronic illnesses. The study involved 50 geriatric respondents to whom the researcher-made questionnaires adapted from the Morisky Medication Adherence Scale (MMAS-8) were administered. Most respondents exhibited a predominantly very high adherence level to their medication regimen, indicating overall satisfactory adherence. Various demographic factors such as age, gender, education, occupation, marital status, income, and clinical diagnosis did not significantly associate with adherence. Exploratory factor analysis identified four key factors affecting medication adherence namely: effectiveness of the medicine, desire to be treated, physician’s good prescription, and influence of positive observations. The study recommends that healthcare providers should implement a continuous monitoring and evaluation process, facilitating adjustments and refinements based on evolving circumstances among the elderly population. Healthcare systems and policymakers should explore strategies to make medications more affordable and accessible, particularly for those with limited financial resources. Future research should delve deeper into each factor to gain a comprehensive understanding of medication adherence.
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Palikhey, Anjan, Sandeep Jaisi, Dilip Sharma Banjade, et al. "Adherence to Antihypertensive Medications among Nepalese Hypertensive Patients at A Tertiary Care Hospital of Nepal." Journal of National Heart and Lung Society Nepal 3, no. 2 (2024): 118–22. https://doi.org/10.3126/jnhls.v3i2.68668.
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Background: Hypertension remains a significant public health concern globally, contributing to the burden of cardiovascular disease and associated morbidity and mortality. Effective management of hypertension often relies on adherence to antihypertensive medication regimens. However, non-adherence to prescribed medications presents a formidable challenge in achieving optimal blood pressure control and preventing complications. The main objective of this study was to find out the adherence to antihypertensive medication among Nepalese hypertensive patients at a tertiary care hospital. Methods: This analytical cross-sectional study was conducted at the outpatient department of medicine of UCMS-TH. A total of 384 participants were involved in the study, where the adherence rate to anti-hypertensive medication was collected using Morisky Medication Adherence Scale (MMAS-8). SPSS version 22 was used to record and analyze the data, and the descriptive results were presented as numbers and percentages. Chi-square test was used to determine the association between adherence and other variables at 95% confidence interval. Results: The study found a very high percentage (85.70%) of adherence to antihypertensive drugs. Forgetfulness was the major reason for the non-adherence 30(54.50%). Age group and educational status of the participants were significantly associated with adherence rate (p<0.05). Conclusion: The study revealed greater number of participants were adherent to antihypertensive medications which helps to better control blood pressure and reduce the risk of complications. Proper counseling can significantly increase the adherence rate.
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Abegaz, Tadesse Melaku, Lamessa Melese Sori, and Hussien Nurahmed Toleha. "Self-Reported Adverse Drug Reactions, Medication Adherence, and Clinical Outcomes among Major Depressive Disorder Patients in Ethiopia: A Prospective Hospital Based Study." Psychiatry Journal 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/5812817.
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Background. There is paucity of data on prevalence of Adverse Drug Reactions (ADRs) and adherence and clinical outcomes of antidepressants. The present study determined the magnitude of ADRs of antidepressants and their impact on the level of adherence and clinical outcome. Methods. A prospective cross-sectional study was conducted among depression patients from September 2016 to January 2017 at Gondar University Hospital psychiatry clinic. The Naranjo ADR probability scale was employed to assess the ADRs. The rate of medication adherence was determined using Morisky Medication Adherence Measurement Scale-Eight. Results. Two hundred seventeen patients participated in the study, more than half of them being males (122; 56.2%). More than one-half of the subjects had low adherence to their medications (124; 57.1%) and about 186 (85.7%) of the patients encountered ADR. The most common ADR was weight gain (29; 13.2%). More than one-half (125; 57.6%) of the respondents showed improved clinical outcome. Optimal level of medication adherence decreased the likelihood of poor clinical outcome by 56.8%. Conclusion. ADRs were more prevalent. However, adherence to medications was very poor in the setup. Long duration of depression negatively affects the rate of adherence. In addition, adherence was found to influence the clinical outcome of depression patients.