Journal articles: 'Morphologic parameters'

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Narwani, Riya, and Dr Vijaylaxmi Vijaylaxmi. "Analysis of Morphologic and Morphometric Parameters of Human Mandible." Asian Journal of Medical Research 8, no. 2 (2019): AT01—AT03. http://dx.doi.org/10.21276/ajmr.2019.8.2.at1.

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Zhang, Yuanli, Xianchao Xu, and Zhan Liu. "Comparison of Morphologic Parameters of Temporomandibular Joint for Asymptomatic Subjects Using the Two-Dimensional and Three-Dimensional Measuring Methods." Journal of Healthcare Engineering 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/5680708.

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The differences of temporomandibular joint (TMJ) morphologic parameters by using two-dimensional (2D) and three-dimensional (3D) measuring methods were compared. Ten asymptomatic subjects (26.75 ± 4.89 years) were randomly recruited. The 3D models of the maxilla, mandible, and teeth were reconstructed according to cone-beam computed tomography (CBCT) image data. The morphologic parameters of TMJs were measured by the 2D CBCT measuring method (group A) and the 3D reconstruction model measuring method (group B), respectively. The morphologic parameters in each group were assessed by paired samplest-test, and the statistical significance was achieved whenp<0.05. The horizontal condylar angle (HCA), sagittal ramus angle (SRA), medial joint space (MJS), lateral joint space (LJS), superior joint space (SJS), and anterior joint space (AJS) in group A were significantly smaller than those in group B (p<0.05). The HCA on the left side was significantly smaller than that on the right side in group A (p<0.05). However, all the morphologic parameters in group B were not significantly different between left and right sides. In conclusion, there were significant differences for the morphologic parameters of TMJ measured on 2D CBCT and 3D models. 3D measuring method should be used for the detection of TMJ morphology in clinical practice.

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Sadowski, Lukasz, and Thomas G. Mathia. "The Metrology of Ground Concrete Surfaces Morphology With 3D Laser Scanner." Management and Production Engineering Review 6, no. 2 (2015): 40–44. http://dx.doi.org/10.1515/mper-2015-0015.

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Abstract This paper is devoted to machining of concrete by grinding and the metrology of its surface morphologies. The surface morphology is still open problem from metrological as well as mathematical morphology points of views. In order to understand better abrasive process the raw morphologic state is compared with the ground concrete surfaces. The most significant results are presented in the form of profiles, 3D isometric views and isotropy analysis. Several 3D surface roughness parameters were calculated.

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Im, Sang-Kyu, Ki Young Lee, Hae Seong Lim, Dong Uk Suh, and Jung-Hee Lee. "Optimized Surgical Strategy for Adult Spinal Deformity: Quantitative Lordosis Correction versus Lordosis Morphology." Journal of Clinical Medicine 10, no. 9 (2021): 1867. http://dx.doi.org/10.3390/jcm10091867.

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Background: In surgical correction of adult spinal deformity (ASD), pelvic incidence (PI)-lumbar lordosis (LL) plays a key role to restore normal sagittal alignment. Recently, it has been found that postoperative lordosis morphology act as an important factor in preventing mechanical complications. However, there have been no studies on the effect of postoperative lordosis morphology on the restoration of sagittal alignment. The primary objective of this study was to evaluate the effect of postoperative lordosis morphology on achievement of optimal sagittal alignment. The secondary objective was to find out which radiographic or morphologic parameter affects sagittal alignment in surgical correction of ASD. Methods: 228 consecutive patients with lumbar degenerative kyphosis who underwent deformity correction and long-segment fixation from T10 to S1 with sacropelvic fixation and follow-up over 2 years were enrolled. Patients were divided according to whether optimal alignment was achieved (balanced group) or not (non-balanced group) at last follow-up. We analyzed the differences of postoperative radiographic parameters and morphologic parameters between two groups. Correlation analysis and stepwise multiple linear regression analysis was performed to predict the effect of PI-LL and morphologic parameters on the sagittal vertical axis (SVA). Results: Of 228 patients, 195 (85.5%) achieved optimal alignment at last follow-up. Two groups significantly differed in postoperative and last follow-up LL (p < 0.001 and p = 0.028, respectively) and postoperative and last follow-up PI-LL (p < 0.001 and p = 0.001, respectively). Morphologic parameters did not significantly differ between the two groups except lower lordosis arc angle (=postoperative sacral slope). In correlation analysis and stepwise multiple linear regression analysis, postoperative PI-LL was the only parameter which had significant association with last follow-up SVA (R2 = 0.134, p < 0.001). Morphologic parameters did not have any association with last follow-up SVA. Conclusions: When planning spine reconstruction surgery, although considering postoperative lordosis morphology is necessary, it is still very important considering proportional lordosis correction based on individual spinopelvic alignment (PI-LL) to achieve optimal sagittal alignment.

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Amini, Fariborz, Ziba Mashayekhi, Hajir Rahimi, and Golnaz Morad. "Craniofacial Morphologic Parameters in a Persian Population." Journal of Craniofacial Surgery 25, no. 5 (2014): 1874–81. http://dx.doi.org/10.1097/scs.0000000000000902.

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Kvesić, Stjepan, Mirzeta Memišević Hodžić, Matijaž Čater, and Dalibor Ballian. "Morphologic variability of the Acer campestre L. populations in Bosnia and Herzegovina." Acta Biologica Sibirica 7 (November 15, 2021): 327–43. http://dx.doi.org/10.3897/abs.7.e73001.

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Morphologic variability from 25 populations of Acer campestre L. in Bosnia and Herzegovina was analyzed. Morphometric structure of variability and between-population variability was performed based on 10 fruit-parameter characteristics and 19 leaf-parameter characteristics using multivariate statistical analysis. Results confirmed the separation of three submediterranean populations as a group in relation to other tested populations, from which the Banja Luka population is different. Measured leaf parameters were confirmed as a predominant carrier of the morphologic separation between populations. In other Acer species populations within A. monspessulanum and A. intermedium species are separated mainly by fruit and much less by leaf parameters. The southernmost submediterranean populations from Trebinje, Ljubu&scaron;ki, and Mostar regions have smaller leaf areas, which consequently places them within the same morphologic group; their variability is in tight connection with eco-geo-graphical factors, where the ecological distance is a much better predictor of morphological variability compared to geographical distance. The air temperature had the biggest influence on morphological variability regarding the highest in-between correlation. Achieved results may serve for the continuation of the research in other areas of Acer campestre to determine the interactive effect of ecological, geographical, climatic, and migrational factors on their morphologic population plasticity.

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Kvesić, Stjepan, Hodžić Mirzeta Memišević, Matijaž Čater, and Dalibor Ballian. "Morphologic variability of the Acer campestre L. populations in Bosnia and Herzegovina." Acta Biologica Sibirica 7 (November 15, 2021): 327–43. https://doi.org/10.3897/abs.7.e73001.

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Morphologic variability from 25 populations of Acer campestre L. in Bosnia and Herzegovina was analyzed. Morphometric structure of variability and between-population variability was performed based on 10 fruit-parameter characteristics and 19 leaf-parameter characteristics using multivariate statistical analysis. Results confirmed the separation of three submediterranean populations as a group in relation to other tested populations, from which the Banja Luka population is different. Measured leaf parameters were confirmed as a predominant carrier of the morphologic separation between populations. In other Acer species populations within A. monspessulanum and A. intermedium species are separated mainly by fruit and much less by leaf parameters. The southernmost submediterranean populations from Trebinje, Ljubu&scaron;ki, and Mostar regions have smaller leaf areas, which consequently places them within the same morphologic group; their variability is in tight connection with eco-geo-graphical factors, where the ecological distance is a much better predictor of morphological variability compared to geographical distance. The air temperature had the biggest influence on morphological variability regarding the highest in-between correlation. Achieved results may serve for the continuation of the research in other areas of Acer campestre to determine the interactive effect of ecological, geographical, climatic, and migrational factors on their morphologic population plasticity.

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Zhang, Zhao, and Teng Li. "A Molecular Mechanics Study of Morphologic Interaction between Graphene and Si Nanowires on a SiO2Substrate." Journal of Nanomaterials 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/374018.

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We study the morphologic interaction between graphene and Si nanowires on a SiO2substrate, using molecular mechanics simulations. Two cases are considered: (1) a graphene nanoribbon intercalated by a single Si nanowire on a SiO2substrate and (2) a blanket graphene flake intercalated by an array of Si nanowires evenly patterned in parallel on a SiO2substrate. Various graphene morphologies emerge from the simulation results of these two cases, which are shown to depend on both geometric parameters (e.g., graphene nanoribbon width, nanowire diameter, and nanowire spacing) and material properties (e.g., graphene-nanowire and graphene-substrate bonding strength). While the quantitative results at the atomistic resolution in this study can be further used to determine the change of electronic properties of graphene under morphologic regulation, the qualitative understandings from this study can be extended to help exploring graphene morphology in other material systems.

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Mac-Thiong, Jean-Marc, and Hubert Labelle. "Morphologic parameters of sacropelvic anatomy affecting spinal pathology." Current Orthopaedic Practice 19, no. 4 (2008): 388–96. http://dx.doi.org/10.1097/bco.0b013e3282f79b69.

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Fashae, Olutoyin A., and Adetoye Faniran. "Downstream Morphologic Characteristics of the Alluvial Section of Lower River Ogun, Nigeria." Journal of Environmental Geography 8, no. 1-2 (2015): 1–10. http://dx.doi.org/10.1515/jengeo-2015-0001.

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Abstract Rivers constitute an important focus of attention in surface water studies because of their dynamic nature. Therefore, natural rivers develop a wide range of channel forms whose characteristics vary as a function of the position within the fluvial systems. This study examined the river channel morphologic parameters along the alluvial section of River Ogun in South western Nigeria. Data on the channel morphologic variables were collected through field measurement of the bankfull cross sectional characteristics of the river from where the longitudinal characteristics were defined. 48 cross sections were randomly established at bankfull stage along the river channel stretch of 90 km. Bankfull depth and width at each of the cross sections were determined using sonar (electronic sounding machine) that was mounted to a boat. Velocity was measured with the aid of a current meter, while other morphological parameters were estimated from the field data. Analysis of variance revealed that downstream morphological characteristics of the river varies distinctively at each cross section with bedslope as the most significantly varied among all other morphologic parameters (F=91.18; P=0.00). Pearson product moment correlation technique revealed that bankfull width had a correlation of 0.8 and 0.9 with wetted perimeter and cross sectional area respectively while bankfull depth (maximum) had correlations of 0.9, 0.8 and 0.78 with hydraulic radius, wetted perimeter and cross sectional area respectively. The research also revealed that gradient affects the discharge with a positive correlation of 0.9. The study ascertains the extent of variability in the morphologic characteristic of River Ogun which provides scientific basis for river maintenance and management.

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Litvinenko, A. N., D. A. Zinovkin, and T. S. Ugolnik. "Morphologic and Morphometric Parameters of the Liver Tissue of Laboratory Animals After Modeling of Chronic Stress." Health and Ecology Issues, no. 4 (December 28, 2018): 56–60. http://dx.doi.org/10.51523/2708-6011.2018-15-4-11.

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Objective: to study changes in the morphologic and morphometric parameters of the liver tissue in male Wistar rats under chronic Ortiz stress. Material and methods. The study was conducted on 50 male Vistor rats. The experimental group of the animals was subjected to 10-day chronic stress by Ortiz. The morphologic and morphometric parameters of the liver tissue of the animals exposed to chronic stress were studied. Results. The morphologic changes in the liver of the animals which had sustained chronic stress were characterized by impaired blood circulation and degenerative changes of hepatocytes. At the same time, a statistically significant increase in the percentage of binuclear hepatocytes (p = 0.046) and functional cariocellular index (p = 0.03) was found. Conclusion. The effect of chronic stress leads to a change in the morphologic and morphometric parameters of the liver tissue with activation of reparative processes.

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Nicolau, Antonela-Anca, and Mariana Așchie. "Morphologic analysis of periumbilical nevi." ARS Medica Tomitana 19, no. 3 (2013): 170–75. http://dx.doi.org/10.2478/arsm-2013-0030.

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Abstract A large number of publications recognize that there are melanocytic lesions with microscopic features similar to melanoma, related to their location, with no prognostic importance. Those locations are represented by the ear, the milk lines (axillary, breast, periumbilical and inguinal regions), palms, soles and flexural regions. The periumbilical nevi are included by some authors in the category of the flexural nevi. In 2004, Rongioletti et al., performed a study on a number of 101 breast nevi, considering 10 histologic parameters. Starting from Rongioletti’s study we measured 10 histologic parameters on 121 nevi (26 from the periunmbilical area) and notes with 0 if absent or impossible to evaluate and with 1 if present. The score for each lesion ranged from 0 to 6 and we compared the features of the periumbilical nevi with the nevi from the control sites and found that the ones in the periumbilical area have more frequently atypical features than the nevi from the other sites (lemtiginous proliferation of nevus cells, architectural disorder of the nevus cell nests and stromal reactions as dermal fibroplasias and dermal lymphocytic infiltrate). We also performed immunohistochemical examination on lesions that presented three or more of the examined histologic parameters, but the results were not very suggestive. The conclusion of this study is that the atypical features of the breast nevi are only site related atypias and have no hormonal influences

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Erdoĝan, F., A. Demirel, and Ö. Polat. "Prognostic significance of morphologic parameters in renal cell carcinoma." International Journal of Clinical Practice 58, no. 4 (2004): 333–36. http://dx.doi.org/10.1111/j.1368-5031.2004.00008.x.

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Weaver, Christina M., and Susan L. Wearne. "Neuronal Firing Sensitivity to Morphologic and Active Membrane Parameters." PLoS Computational Biology 4, no. 1 (2008): e11. http://dx.doi.org/10.1371/journal.pcbi.0040011.

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Weaver, Christina M., and Susan Wearne. "Neuronal Firing Sensitivity to Morphologic and Active Membrane Parameters." PLoS Computational Biology preprint, no. 2007 (2005): e11. http://dx.doi.org/10.1371/journal.pcbi.0040011.eor.

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Bureau, Nathalie J., Maguy Deslauriers, Marianne Lepage-Saucier, et al. "Rotator Cuff Tear Morphologic Parameters at Magnetic Resonance Imaging." Journal of Computer Assisted Tomography 42, no. 5 (2018): 784–91. http://dx.doi.org/10.1097/rct.0000000000000740.

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Domsik, Péter, Anita Kalapos, Csaba Lengyel, Andrea Orosz, Tamás Forster, and Attila Nemes. "Relationship between mitral annular and left atrial function as assessed by three-dimensional speckle-tracking echocardiography in healthy volunteers. Results from the MAGYAR-Healthy Study." Orvosi Hetilap 155, no. 38 (2014): 1517–23. http://dx.doi.org/10.1556/oh.2014.29975.

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Introduction: Left atrium is a heart chamber with dinamic motion communicating with left ventricle through the mitral valve and its annulus. Aim: The aim of the present study was to analyse whether relationships could exist between three-dimensional speckle-tracking echocardiography-derived morphologic and functional parameters of the left atrium and mitral annulus in healthy subjects. Method: The present study comprised 35 healthy volunteers. Maximum (Vmax) and minimum (Vmin) left atrial volumes and left atrial volume before atrial contraction (VpreA) were measured, and several functional parameters based on these volumes were calculated in all cases. Morphologic and functional characteristics of the mitral annulus were also determined. Results: While Vmax showed correlations with both systolic and diastolic mitral annulus parameters, Vmin-VpreA correlated with only systolic ones. While total left atrial stroke volume correlated with both systolic and diastolic mitral annular parameters, passive left atrial stroke volume showed correlations only with diastolic ones. Conclusions: Correlations exist between left atrial and mitral annular morphological and functional characteristics in healthy subjects. Orv. Hetil., 2014, 155(38), 1517–1523.

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Sanguedolce, Francesca, Davide Russo, Vito Mancini, et al. "Morphological and Immunohistochemical Biomarkers in Distinguishing Prostate Carcinoma and Urothelial Carcinoma: A Comprehensive Review." International Journal of Surgical Pathology 27, no. 2 (2018): 120–33. http://dx.doi.org/10.1177/1066896918814198.

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The differential diagnosis between high-grade prostate carcinoma and infiltrating urothelial carcinoma (UC) in transurethral resection prostate specimens as well as cystoprostatectomy specimens may often be challenging due to morphologic and clinical overlap of the 2 entities. Such distinction has critical therapeutic and staging consequences, yet it is hampered by both issues in morphology and by the low accuracy rates of single immunohistochemical markers, as reported in literature. This review aims to provide a comprehensive analysis of the available morphological and immunohistochemical parameters, which may allow to discriminate between prostate carcinoma and urothelial carcinoma in the proper clinical context and to discuss their diagnostic applications in daily practice.

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Zhuravel, Sergey V., Elena V. Klychnikova, Nataliya K. Kuznetsova, et al. "Effect of infusion therapy on renal function and laboratory parameters in one-day experiment." Medical Bulletin of the Main Military Clinical Hospital named after N.N. Burdenko 4, no. 3 (2023): 15–24. http://dx.doi.org/10.53652/2782-1730-2023-4-3-15-24.

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Changing views on the composition of infusion therapy in medical practice over the last decade is associated with certain side effects of infusion solutions. It is of relevance to study their influence on the kidneys, metabolism, electrolyte composition and, ultimately, on the patient's treatment results. The aim of the present work is to determine the effect of colloid and crystalloid solutions on renal function and laboratory parameters in experiment. The experimental study was performed on 28 rats (males) of Wistar line. Four experimental groups were formed: I control (n=7) — intact animals (without infusions and laparotomy), II (n=7) — laparotomy without infusions, III (n=7) — laparotomy + infusion of 6 ml of 6% hydroxyethyl starch, IV (n=7) — laparotomy + infusion of 6 ml of 0.9% sodium chloride solution. All animals underwent hematologic and biochemical blood tests, morphologic studies of kidneys. The most pronounced changes in blood tests and morphology were revealed during infusion of 6 ml of 0.9% sodium chloride solution. We observed leukopenia, decreased levels of albumin, cystatin C, cholesterol, alpha-amylase activity, increased concentration of bile acids compared to groups I and II. Morphologic study revealed significant dilatation of capsules of a part of tubules with dilated lumen of their capillaries, irregularly expressed full blood vessels. In addition, displacement of nuclei of nephrothelium to the apical pole of the cell was noted in the absence of homogeneity of cytoplasm with the presence of "enlightenments" in it. Infusion of hydroxyethyl starch did not change the main hematologic and biochemical blood parameters, except for the increase in alpha-amylase activity. Morphologic study did not reveal changes that would lead to acute kidney damage. All changes were reversible. Infusion of physiological solution caused shifts in both hematologic and biochemical blood parameters, in particular, hypoalbuminemia. The results of histologic study indicated redistribution of fluid in the interstitium.

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Welton, K. Linnea, Matthew J. Kraeutler, Tigran Garabekyan, and Omer Mei-Dan. "Radiographic Parameters of Adult Hip Dysplasia." Orthopaedic Journal of Sports Medicine 11, no. 2 (2023): 232596712311528. http://dx.doi.org/10.1177/23259671231152868.

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As knowledge about the origin and morphologic characteristics of hip pain in the young adult has evolved, so too has the clinician’s ability to assess for various pathologies of the hip on radiographs, magnetic resonance imaging (MRI)/magnetic resonance arthrography (MRA), and computed tomography (CT). Because there is no algorithm at this time directly indicating what to do in more subtle hip morphologies, such as microinstability and borderline hip dysplasia (BHD), a skilled hip preservation specialist must use multiple imaging sources and know how to interpret them correctly. Imaging parameters used in the workup for hip dysplasia and BHD include the lateral center-edge angle, Tönnis angle, iliofemoral line, and presence of an upsloping lateral sourcil or everted labrum, among many others. The purpose of this narrative review was to detail various established criteria and parameters on anteroposterior pelvis plain radiographs, MRI/MRA, and CT that assist in defining the nature and severity of instability present in a dysplastic hip, thereby aiding in the development of patient-specific surgical treatment plans.

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Ho, Allen L., Ning Lin, Kai U. Frerichs, and Rose Du. "Intrinsic, Transitional, and Extrinsic Morphological Factors Associated With Rupture of Intracranial Aneurysms." Neurosurgery 77, no. 3 (2015): 433–42. http://dx.doi.org/10.1227/neu.0000000000000835.

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Abstract BACKGROUND: As diagnosis and treatment of unruptured intracranial aneurysms continues to increase, management principles remain largely based on size. This is despite mounting evidence that aneurysm location and other morphologic variables could play a role in predicting overall risk of rupture. Morphological parameters can be divided into 3 main groups, those that are intrinsic to the aneurysm, those that are extrinsic to the aneurysm, and those that involve both the aneurysm and surrounding vasculature (transitional). OBJECTIVE: We present an evaluation of intrinsic, transitional, and extrinsic factors and their association with ruptured aneurysms. METHODS: Using preoperative computed tomographic angiography, we generated 3-dimensional models of aneurysms and their surrounding vasculature with Slicer software. Using univariate and multivariate analyses, we examined the association of intrinsic, transitional, and extrinsic aspects of aneurysm morphology with rupture. RESULTS: Between 2005 and 2013, 227 cerebral aneurysms in 4 locations were evaluated/treated at a single institution, and computed tomographic angiographies of 218 patients (97 unruptured and 130 ruptured) were analyzed. Ruptured aneurysms analyzed were associated with clinical factors of absence of multiple aneurysms and history of no prior rupture, and morphologic factors of greater aspect ratio. On multivariate analysis, aneurysm rupture remained associated with history of no prior rupture, greater flow angle, greater daughter-daughter vessel angle, and smaller parent-daughter vessel angle. CONCLUSION: By studying the morphology of aneurysms and their surrounding vasculature, we identified several parameters associated with ruptured aneurysms that include intrinsic, transitional, and extrinsic factors of cerebral aneurysms and their surrounding vasculature.

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Rana, Raveshwar S., Isha Slathia, and Ravinder S. Rana. "Study the Physico-Morphologic Parameters of Neat Cryopreserved Murrah Semen." Advances in Zoology and Botany 10, no. 3 (2022): 64–74. http://dx.doi.org/10.13189/azb.2022.100304.

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Medeiros, L. Jeffrey, Arnold B. Gelb, and Lawrence M. Weiss. "Renal cell carcinoma.Prognostic significance of morphologic parameters in 121 cases." Cancer 61, no. 8 (1988): 1639–51. http://dx.doi.org/10.1002/1097-0142(19880415)61:8<1639::aid-cncr2820610823>3.0.co;2-f.

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Spitz, L., J. Schmidt, J. Korte, et al. "Morphologic and hemodynamic analysis of intracranial mirror aneurysms." Current Directions in Biomedical Engineering 10, no. 2 (2024): 87–90. http://dx.doi.org/10.1515/cdbme-2024-1074.

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Abstract Intracranial mirror aneurysms are pathologic dilatations of cerebral arteries that occur at identical locations in both hemispheres. They do not always have identical sizes, shapes, or rupture states, despite identical patient-specific risk factors. As a subgroup of multiple aneurysms and thus small amounts of data, clinical research about their causes and development has not been conclusive. Using eight patients with 16 mirror aneurysms with different rupture states, we investigated differences between the hemispheres. We virtually performed stitching: detaching the aneurysm domes to place them on the opposite parent vessel to assess the influence of aneurysm morphology and upstream parent vessel shape on hemodynamics. In the unaltered datasets, we found that blood flow within aneurysms in the left hemisphere has higher wall shear stress and velocity. After stitching, we found that both upstream parent vessel as well as aneurysm morphology influence hemodynamics. Morphologic parameters like size, undulation index, and aneurysm angle had a higher influence. In a short rupture risk analysis we found a correlation between rupture and aspect ratio and non-sphericity index. Overall, we found possible indicators for mirror aneurysm analysis that illustrated the importance of morphological analysis, though more datasets are necessary for conclusive statements about special treatment for mirror aneurysms.

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Bozzato, Alessandro, Johannes Zenk, Holger Greess, et al. "Potential of ultrasound diagnosis for parotid tumors: Analysis of qualitative and quantitative parameters." Otolaryngology–Head and Neck Surgery 137, no. 4 (2007): 642–46. http://dx.doi.org/10.1016/j.otohns.2007.05.062.

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Objective Histology of parotid tumors determines the extent of surgery. The aim was to test ultrasound (US) contrast enhancer-kinetics to identify histologic entities, possibly being superior to qualitative morphological parameters. Study Design In a cross-sectional assessment of ultrasound diagnosis, the subjective US-classification was compared with contrast analysis with histology as gold standard. Subjects and Methods A total of 64 male and 61 female patients with a mean age of 54 years were included, with 13 malignant tumors. These were classified with US morphology, then time-dependent contrast medium analysis. Results A total of 92.8% of tumors were classified correctly as malignant or benign. The sensitivity, specificity, positive- and negative-predictive values were 66.7%, 86.3%, 60.6%, and 89.1% for differentiating Warthin tumors, but only 46.2%, 98.2%, 75%, and 94% for malignant lesions. Contrast parameters yielded significant parameters for benign tumors, not for malignant entities. Conclusion Although contrast medium analysis provided statistical criteria, these, however, do not possess the ability to improve the diagnostic prediction of tumor histology. Neither the morphologic classification nor contrast medium analysis was able to identify a malignant lesion sufficiently.

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Maatooq, Jaafar S., and Luay K. Hameed. "2D Model to Investigate the Morphological and Hydraulic Changes of Meanders." Engineering and Technology Journal 38, no. 1A (2020): 9–19. http://dx.doi.org/10.30684/etj.v38i1a.95.

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River engineering investigations require some level of hydrodynamic and morphologic analysis. The detailed of the hydraulic and morphologic features through meander evolution can be recorded by the numerical model spatially and temporally. The Center for Computational Hydro-science and Engineering, two- dimensional model (CCHE2D V3.29) was adopted to investigate the hydraulic and morphologic changes through meander’s evolution. Through the experimental work, a series of experiments runs were carried out through combining different geometric and hydraulic parameters to produce different experiment conditions. These parameters are flow rate, bed slope, and different initial incised and wide channels for both rectangular and trapezoidal sections. The CCHE2D model was calibrated and verified using two sets of experimental data. According to the computed values of statistical indicators, BIAS, NSE, and MAE of 0.0084, 0.96, and 0.0132 respectively for water level simulation, and 0.007,0.94, and 0.0182 respectively for bed level simulation, the calibrated Manning’s roughness which gives an acceptable agreement between simulated and measured water and bed levels was 0.029. The verification results were evaluated by the same statistical indicators of BIAS, NSE, and MAE of 0.09, 0.81, and 0.018, respectively, as evidenced by the statistical indicators, values that the CCHE2D model was reasonably capable of simulating the hydraulic and morphological changes through meander evolution.

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Tayyib,, Nahla, Mabrouk Abo-Zaid, Ahmed Ismail, Soha Mohammed, and Ali Amin. "COVID-19 Case Report: Circulating blood cells morphology in convalescent patient." Journal of Umm Al-Qura University for Medical Sciences 8, no. 2 (2022): 25–28. http://dx.doi.org/10.54940/ms38961714.

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Objective: Many studies have detailed the mechanisms of infection and quantitative peripheral blood findings reported in severe acute respiratory syndrome virus 2 (SARS-CoV-2) patients during the severity of infection since the start of the coronavirus disease 2019 (COVID-19) pandemic. Though, only a few studies have described blood morphologic abnormalities. We report peripheral blood cells morphologic changes in convalescent patient. Design: We performed complete blood counts (CBC), and blood smear of 52-year-old patient who were COVID-19 positive test by (RT-PCR), from May 20, 2021, through June 15, 2021. The peripheral blood smears of a convalescent patient were collected the morphological structures of Leukocytes, red blood cells (RBCs) and platelets were examined and documented, after 3 weeks from infection with COVID-19 RT-PCR was negative to look for viral changes on blood cells morphology. Results: On a complete blood count (CBC), the most common quantitative hematologic abnormalities were mild anemia with RBCs showed no abnormality followed by WBCs normal in count, and relative lymphopenia. Neutrophils showed the most substantial morphologic alterations with C-shaped bi-lobulated nuclei, coarse toxic granulations and cytoplasmic vacuolization. Activated neutrophil granulocytes with elongated cell membrane, pseudo Pelger–Huët anomaly-like nuclei, ring form nuclei and pyknotic nucleus. Lymphocytes were atypical reactive lymphocytes with cytoplasmic pseudopod formation. Plasmacytoid lymphocytes with an eccentric nucleus and deeply basophilic cytoplasm are frequently seen. Monocytes seen in active form with cytoplasmic vacuolization and cytoplasm contain granules, with pseudopod formation. Platelets were adequate in number with giant platelets are occasionally seen. Smudge cell is also seen. RBCs were normocytic; normochromic. Conclusion: Our work identifies and characterizes significant morphologic abnormalities in recovered COVID-19 patients' peripheral blood cells. Understanding these morphologic changes, in addition to established hematologic parameters, can help follow with COVID-19 patient during recovery through serial CBC and peripheral smear examination. Serial complete blood count and blood film review may become an essential tool to help physicians allocate patients to risk categories based on morphological findings if these proposals are supported by large-scale investigations of convalescent patients.

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Konukiewitz, Björn, Maxime Schmitt, Miguel Silva, et al. "Loss of CDX2 in colorectal cancer is associated with histopathologic subtypes and microsatellite instability but is prognostically inferior to hematoxylin–eosin-based morphologic parameters from the WHO classification." British Journal of Cancer 125, no. 12 (2021): 1632–46. http://dx.doi.org/10.1038/s41416-021-01553-0.

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Abstract Background Immunohistochemical loss of CDX2 has been proposed as a biomarker of dismal survival in colorectal carcinoma (CRC), especially in UICC Stage II/III. However, it remains unclear, how CDX2 expression is related to central hematoxylin–eosin (HE)-based morphologic parameters defined by 2019 WHO classification and how its prognostic relevance is compared to these parameters. Methods We evaluated CDX2 expression in 1003 CRCs and explored its prognostic relevance compared to CRC subtypes, tumour budding and WHO grade in the overall cohort and in specific subgroups. Results CDX2-low/absent CRCs were enriched in specific morphologic subtypes, right-sided and microsatellite-instable (MSI-H) CRCs (P < 0.001) and showed worse survival characteristics in the overall cohort/UICC Stage II/III (e.g. DFS: P = 0.005) and in microsatellite stable and left-sided CRCs, but not in MSI-H or right-sided CRCs. Compared with CDX2, all HE-based markers showed a significantly better prognostic discrimination in all scenarios. In multivariate analyses including all morphologic parameters, CDX2 was not an independent prognostic factor. Conclusion CDX2 loss has some prognostic impact in univariate analyses, but its prognostic relevance is considerably lower compared to central HE-based morphologic parameters defined by the WHO classification and vanishes in multivariate analyses incorporating these factors.

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Sugihara, Kazunobu, Yasuyuki Takai, Ryo Kawasaki, et al. "Comparisons between retinal vessel calibers and various optic disc morphologic parameters with different optic disc appearances: The Glaucoma Stereo Analysis Study." PLOS ONE 16, no. 7 (2021): e0250245. http://dx.doi.org/10.1371/journal.pone.0250245.

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The Glaucoma Stereo Analysis Study (GSAS) is a multicenter collaborative study of the characteristics of glaucomatous optic disc morphology using a stereo fundus camera. This study evaluated the retinal vessel calibers and correlations using GSAS fundus photographs between retinal vessels and 38 optic nerve head (ONH) morphologic parameters comprehensively. In all 240 eyes, the mean central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) were 138.4 and 216.5 μm, respectively; the CRAE correlated with age, visual field scores and 19 ONH parameters and CRVE correlated with age, intraocular pressure, visual field scores and 11 ONH parameters. Among the different optic disc appearances including focal ischemia (FI) (n = 53, 22%), generalized enlargement (GE) (n = 53, 22%), myopic glaucoma (MY) (n = 112, 47%), and senile sclerosis (SS) (n = 22, 9%), the CRAE did not differ significantly; CRVE was significantly narrower in SS than in FI and MY. In FI, GE, MY, and SS disc types, CRAE correlated with 3, 14, 9, and 2 ONH parameters, respectively, and CRVE corelated with 9, 0, 12, and 6 ONH parameters, respectively. We confirmed previous observations on the effect of retinal vessel narrowing on glaucomatous changes in the ONH and visual field. The associations between retinal vessel caliber and ONH morphologic parameters vary among different optic disc appearances, suggesting different effects of vascular changes in each disc type.

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Matvieienko, Mariia, Alena Gryshchenko, Nadiia Baranova, Arora Sukesh, and Ievgen Bausov. "CHANGES IN THE MORPHOLOGIC STATE OF RED BLOOD CELLS IN PATIENTS WITH POLYTRAUMA." EUREKA: Health Sciences 4 (July 31, 2020): 64–70. http://dx.doi.org/10.21303/2504-5679.2020.001373.

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The measurement of RBC indices is of particular importance as an indirect intermediate component of the recovery process after exposure to hypoxia, ischemia, hypothermia in patients with traumatic disease due to polytrauma. The aim of this study was to evaluate the parameters of the morphologic state of red blood cells as a reaction of patients with traumatic disease. Materials and methods.A prospective study was carried out evaluation of 120 patients suffering from polytrauma. The patients were divided into 3 groups according to the principle of using additional substances as a part of IC. The parameters of morphologic state of red blood cells were studied. Results and discussion. The course of acute and early periods of traumatic disease has accompanied variability morphological forms of red blood cells, as evidenced by a decrease in MCV and RDW increased levels of the 3rd to 5th day. The optimized therapy used in the treatment of patients, has a positive effect on the parameters of red blood cells, contributes to a better recovery of red blood cells after hypoxia resulting multiple trauma. Conclusion. The study has demonstrated variations in the morphologic properties of red blood cells in the acute and early period of traumatic disease, as confirmed by pathological changes of the erythrocyte indices. The administration of the proposed therapy with the use of D-fructose-1.6-diphosphate sodium salt of hydrate has a positive effect on the parameters of red blood cells, contributes to a better recovery after hypoxia resulting multiple trauma. Given this, the calculations of the red blood cell indices may carry additional diagnostic information, which allows identify trends for not obvious pathological changes and quality of treatment.

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SA, MELKA COELHO, THALITA SANTANA CONCEIÇÃO, EDILMAR DE MOURA SANTOS, et al. "ASSOCIATION OF MORPHOLOGIC PARAMETERS WITH PROGNOSTIC PARAMETERS IN PATIENTS WITH ORAL TONGUE SQUAMOUS CELL CARCINOMA." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 124, no. 2 (2017): e134. http://dx.doi.org/10.1016/j.oooo.2017.05.367.

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Sbrodone, Sandro, Adele Ragucci, Gennarfrancesco Iaccarino, Domenico de Robertis, Giovan Battista Scazzi, and Michele Lanza. "Corneal Distortion and Corneal Morphological Parameters in Naïve Eyes Analyzed with a Scheimpflug Camera." Modern Health Science 3, no. 2 (2020): p22. http://dx.doi.org/10.30560/mhs.v3n2p22.

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Background: The study of the corneal biomechanical properties (CBP) is gaining always more interest, thanks to the applications to refractive surgery and to the overall management of several corneal diseases. Purpose: To analyze the eventual relationships between corneal distortion and morphologic features in healthy subjects. Methods: one eye of one hundred and fifty-two healthy participants, 87 women and 65 men, aging from 23 to 65 years old, were evaluated in this study. Every eye underwent a complete clinical examination, that included also a tomographic scan using Pentacam HR (Oculus, Wetzlar, Germany) and a biomechanical evaluation using Corvis ST (Oculus, Wetzlar, Germany). Linear regressions among refractive defect, corneal volume (CV), anterior corneal curvature and central corneal thickness (CCT) vs corneal biomechanical features provided by Corvis ST have been ran using SPSS software version 18.0. Results: Corneal distortion factors showed a low correlation both with corneal morphological parameters and with refractive defect. No significant correlations (p> 0.01) were found among morphologic and biomechanical features evaluated. Discussion: results observed in this study could help in recognize the healthy range of values of CBP parameters provided by CST. This information could be very useful in many ophthalmology topics such as the accurate IOP measurement, the early diagnosis of corneal degenerations, such as keratoconous, and the screening of subject undergoing refractive surgery. Conclusions: even if data of this study need to be confirmed in further ones with larger populations, results here observed suggest that Corvis ST is a device providing an evaluation of corneal distortion not influenced by morphological corneal factors. This information could help in better screening and managing the diseased corneas.

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Mariia, Matvieienko, Gryshchenko Alena, Baranova Nadiia, Sukesh Arora, and Bausov Ievgen. "CHANGES IN THE MORPHOLOGIC STATE OF RED BLOOD CELLS IN PATIENTS WITH POLYTRAUMA." EUREKA: Health Sciences, no. 4 (July 31, 2020): 64–70. https://doi.org/10.21303/2504-5679.2020.001373.

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The measurement of RBC indices is of particular importance as an indirect intermediate component of the recovery process after exposure to hypoxia, ischemia, hypothermia in patients with traumatic disease due to polytrauma. The aim of this study was to evaluate the parameters of the morphologic state of red blood cells as a reaction of patients with traumatic disease. Materials and methods.A prospective study was carried out evaluation of 120 patients suffering from polytrauma. The patients were divided into 3 groups according to the principle of using additional substances as a part of IC. The parameters of morphologic state of red blood cells were studied. Results and discussion. The course of acute and early periods of traumatic disease has accompanied variability morphological forms of red blood cells, as evidenced by a decrease in MCV and RDW increased levels of the 3rd to 5th day. The optimized therapy used in the treatment of patients, has a positive effect on the parameters of red blood cells, contributes to a better recovery of red blood cells after hypoxia resulting multiple trauma. Conclusion. The study has demonstrated variations in the morphologic properties of red blood cells in the acute and early period of traumatic disease, as confirmed by pathological changes of the erythrocyte indices. The administration of the proposed therapy with the use of D-fructose-1.6-diphosphate sodium salt of hydrate has a positive effect on the parameters of red blood cells, contributes to a better recovery after hypoxia resulting multiple trauma. Given this, the calculations of the red blood cell indices may carry additional diagnostic information, which allows identify trends for not obvious pathological changes and quality of treatment.

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Stojadinovic, Alexander, Ronald A. Ghossein, Axel Hoos, et al. "Adrenocortical Carcinoma: Clinical, Morphologic, and Molecular Characterization." Journal of Clinical Oncology 20, no. 4 (2002): 941–50. http://dx.doi.org/10.1200/jco.2002.20.4.941.

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PURPOSE: To define multimolecular phenotypes of adrenocortical carcinoma (ACC) and to correlate outcome with morphologic and molecular parameters. PATIENTS AND METHODS: Clinical data were analyzed for 124 patients, histopathologic slides for 67 primary tumors, and tissue specimens for 74 patients (38 primary and 36 metastatic tumors) with ACC and for 38 normal adrenal tissue samples. Molecular expression profiles were investigated by immunohistochemistry. The prognostic significance of 12 gross and histologic parameters in 67 primary ACCs was evaluated. Morphologic and protein expression patterns were correlated with disease-specific survival (DSS). Univariate influence of prognostic factors on DSS was analyzed by log-rank test and multivariate analysis by Cox regression. RESULTS: The median follow-up period was 4.7 years. Significant predictors of DSS included distant metastasis at time of initial presentation; venous, capsular, and adjacent organ invasion; tumor necrosis, mitotic rate, atypical mitosis, and mdm-2 overexpression. Five-year DSS by number (one to six) of adverse histologic parameters was as follows: one to two, 84%; three to four, 37%; more than four, 9% (P = .005).The phenotype Ki-67(−)p53(−)mdm-2(+)cyclinD1(−)Bcl-2(−)p21(−)p27(+) was observed in 83% of normal and 3% of malignant adrenal tissue (P = .01). Molecular phenotypic expression was more heterogeneous in malignant than in normal (10 v five phenotypes) adrenal tissue. CONCLUSION: Meticulous morphologic evaluation, mitotic count, and tumor stage are essential in determining prognosis for patients with ACC. Multimolecular phenotyping demonstrates that the molecular complexity and heterogeneity of these neoplasms are such that targeted therapy needs to be patient specific.

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Andelinovic, Simun, Jerolim Bakotin, Zeljko Dujic, Deny Andelinovic, and Robert Stojan. "Carcinoembryonic Antigen Immunoreactivity Patterns in Colorectal Cancer: Correlation with Morphologic Parameters." Annals of Saudi Medicine 11, no. 5 (1991): 524–29. http://dx.doi.org/10.5144/0256-4947.1991.524.

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Aharon, Devora, Atoosa Ghofranian, Dmitry Gounko, Joseph A. Lee, Alan B. Copperman, and Erkan Buyuk. "MORPHOLOGIC PARAMETERS OF EUPLOID BLASTOCYSTS THAT PREDICT PROGRESSION TO CLINICAL PREGNANCY." Fertility and Sterility 116, no. 3 (2021): e277-e278. http://dx.doi.org/10.1016/j.fertnstert.2021.07.745.

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Thaker, Ameet, and Maria Tretiakova. "Morphologic Assessment of Male Urethral Stricture and Correlation With Clinical Parameters." American Journal of Clinical Pathology 142, suppl_1 (2014): A207. http://dx.doi.org/10.1093/ajcp/142.suppl1.207.

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Li, Yiping, Jason Kim, and Azam Ahmed. "Effect of aneurysm morphologic parameters on occlusion rates following pipeline embolization." Clinical Neurology and Neurosurgery 183 (August 2019): 105395. http://dx.doi.org/10.1016/j.clineuro.2019.105395.

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Höwel, Dennis, Patrick Leitz, Gerrit Frommeyer, et al. "Predictors of Atrial Fibrillation in Patients with Embolic Stroke of Unknown Etiology and Implantable Loop Recorders—Further Insights of the TRACK AF Study on the Role of ECG and Echocardiography." Journal of Clinical Medicine 12, no. 20 (2023): 6566. http://dx.doi.org/10.3390/jcm12206566.

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Aims—Electrocardiography (ECG) and echocardiographic left atrial (LA) parameters may be helpful to assess the risk of atrial fibrillation (AF) in embolic stroke of unknown etiology (ESUS) and could therefore guide intensity of ECG monitoring. Methods—1153 consecutive patients with ischemic stroke or transient ischemic attack (TIA) were analyzed. An internal loop recorder (ILR) was implanted in 104 consecutive patients with ESUS. Multiple morphologic P-wave parameters in baseline 12-channel ECG and echocardiographic LA parameters were measured and analyzed in patients with and without ILR-detected AF. Using logistic regression, we evaluated the predictive value of several ECG parameters and LA dimensions on the occurrence of AF. Results—In 20 of 104 (19%) patients, AF was diagnosed by ILR during a mean monitoring time of 575 (IQR 470–580) days. Patients with AF were significantly older (72 (67–75) vs. 60 (52–72) years; p = 0.001) and premature atrial contractions (PAC) were more frequently observed (40% vs. 2%; p < 0.001) during baseline ECG. All morphologic P-wave parameters did not show a significant difference between groups. There was a non-significant trend towards a larger LA volume index (31 (24–36) vs. 29 (25–37) mL/m2; p = 0.09) in AF patients. Conclusions—Age and PAC are independently associated with incident AF in ESUS and could be used as markers for selecting patients that may benefit from more extensive rhythm monitoring or ILR implantation. In our consecutive cohort of patients with ESUS, neither morphological P-wave parameters nor LA size were predictive of AF.

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Smolle, Josef. "Cellular Automaton Simulation of Tumour Growth – Equivocal Relationships between Simulation Parameters and Morphologic Pattern Features." Analytical Cellular Pathology 17, no. 2 (1998): 71–82. http://dx.doi.org/10.1155/1998/920709.

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Objective:To develop an interpretation procedure which estimates simulation parameters (tumour cell motility, tumour cell adhesion, autocrine and paracrine growth control, stroma destruction) of simulated patterns solely based on morphometric features of the morphologic pattern.Methods:A cellular automaton computer simulation program was developed which produces morphologic patterns by growth of a seed of tumour cells. At the beginning of each simulation run certain simulation parameters are assigned to the tumour cells. After the run has been completed, the resulting pattern is evaluated by a set of morphometric features. Simulation parameters and resulting morphometric features of 27,800 simulations were stored in a database and were used for the evaluation of potential relationships.Results:Correlation analysis showed highly significant correlations between morphometric features on the one hand and the preset simulation parameters (tumour cell motility, tumour cell adhesion, autocrine and paracrine growth control, stroma destruction) on the other. Correlation coefficients, however, varied from 0.72 to 0.99. When only one simulation parameter varied while all others were kept constant, morphometric features yielded a highly reliable estimate of the particular simulation parameter. When variability was extended to 4 simulation parameters, morphometric features were less effective in estimating the setting of the parameters. Though in all patterns tested several possible simulation parameter constellations could be ruled out, morphometric features were usually compatible with more than one set of simulation parameters thus preventing a straightforward interpretation.Conclusions:Though simulation parameters significantly and reproducibly influence the resulting morphologic pattern as characterized by morphometric features, estimates of the simulation parameters based on morphometric features yield equivocal results.

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Frazzetto, Alessia, Fabrizio Roccaforte, Filippo Giannazzo, et al. "Effects of Different Post-Implantation Annealing Conditions on the Electrical Properties of Interfaces to p-Type Implanted 4H-SiC." Materials Science Forum 717-720 (May 2012): 825–28. http://dx.doi.org/10.4028/www.scientific.net/msf.717-720.825.

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This paper reports on the effects of different post-implantation annealings on the electrical properties of interfaces to p-type implanted 4H-SiC. The morphology of p-type implanted 4H-SiC was controlled using a capping layer during post-implantation activation annealing of the dopant. Indeed, the surface roughness of Al-implanted regions strongly depends on the use of the protective capping layer during the annealing. However, while the different morphological conditions do not affect the macroscopical electrical properties of the implanted SiC (such as the sheet resistance), they led to an improvement of the morphology and of the specific contact resistance of Ti/Al Ohmic contacts formed on the implanted regions. These electrical and morphologic improvements were associated with a lowering of Schottky barrier height. Preliminary results showed that the different activation annealing conditions of p-type implanted SiC can affect also the electrical parameters (like threshold voltage and mobility) of lateral MOSFETs.

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Sulaiman, Raed, Pradip De, Jennifer C. Aske, et al. "Identification and Morphological Characterization of Features of Circulating Cancer-Associated Macrophage-like Cells (CAMLs) in Endometrial Cancers." Cancers 14, no. 19 (2022): 4577. http://dx.doi.org/10.3390/cancers14194577.

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The blood of patients with solid tumors contains circulating tumor-associated cells, including epithelial cells originating from the tumor mass, such as circulating tumor cells (CTCs), or phagocytic myeloid cells (differentiated monocytes), such as circulating cancer-associated macrophage-like cells (CAMLs). We report for the first time the identification and in-depth morphologic characterization of CAMLs in patients with endometrial cancers. We isolated CAMLs by size-based filtration on lithographically fabricated membranes followed by immunofluorescence, using a CD45+/CK 8,18,19+/EpCAM+/CD31+/macrophage-like nuclear morphology, from > 70 patients. Irrespective of the histological and pathological parameters, 98% of patients were positive for CAMLs. Two size-based subtypes of CAMLs, <20 µm (tiny) and >20 µm (giant) CAMLs, of distinctive polymorphic morphologies with mononuclear or fused polynuclear structures in several morphological states were observed, including apoptotic CAMLs, CAML–WBC doublets, conjoined CAMLs, CAML–WBC clusters, and CTC–CAML–WBC clusters. In contrast, CAMLs were absent in patients with non-neoplastic/benign tumors, healthy donors, and leucopaks. Enumerating CTCs simultaneously from the same patient, we observed that CTC-positive patients are positive for CAMLs, while 55% out of all CAML-positive patients were found positive for CTCs. Our study demonstrated for the first time the distinctive morphological characteristics of endometrial CAMLs in the context of the presence of CTCs in patients.

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Boulay, Christophe, Gérard Bollini, Jean Legaye, et al. "Pelvic Incidence: A Predictive Factor for Three-Dimensional Acetabular Orientation—A Preliminary Study." Anatomy Research International 2014 (March 18, 2014): 1–9. http://dx.doi.org/10.1155/2014/594650.

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Acetabular cup orientation (inclination and anteversion) is a fundamental topic in orthopaedics and depends on pelvis tilt (positional parameter) emphasising the notion of a safe range of pelvis tilt. The hypothesis was that pelvic incidence (morphologic parameter) could yield a more accurate and reliable assessment than pelvis tilt. The aim was to find out a predictive equation of acetabular 3D orientation parameters which were determined by pelvic incidence to include in the model. The second aim was to consider the asymmetry between the right and left acetabulae. Twelve pelvic anatomic specimens were measured with an electromagnetic Fastrak system (Polhemus Society) providing 3D position of anatomical landmarks to allow measurement of acetabular and pelvic parameters. Acetabulum and pelvis data were correlated by a Spearman matrix. A robust linear regression analysis provided prediction of acetabulum axes. The orientation of each acetabulum could be predicted by the incidence. The incidence is correlated with the morphology of acetabula. The asymmetry of the acetabular roof was correlated with pelvic incidence. This study allowed analysis of relationships of acetabular orientation and pelvic incidence. Pelvic incidence (morphologic parameter) could determine the safe range of pelvis tilt (positional parameter) for an individual and not a group.

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Ravetto, C. "The Limits of Morphology in the Diagnosis of Bladder Tumours." Urologia Journal 60, no. 2 (1993): 138–41. http://dx.doi.org/10.1177/039156039306000203.

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In spite of long-standing experience by pathologists, morphologic criteria in the diagnosis of urothelial cancer are still too subjective in daily practice. Low inter and intraobserver reproducibility are the major problems in the grading of papillary cancer together with the definition of early stromal invasion. More strict morphologic criteria are needed to ensure clinical relevance of the histo-cytological parameters in bladder pathology.

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Snyder, Paul W., Nancy E. Everds, W. A. Craven, Jonathan Werner, Sarah H. Tannehill-Gregg, and Roberto E. Guzman. "Maturity-related Variability of the Thymus in Cynomolgus Monkeys (Macaca fascicularis)." Toxicologic Pathology 44, no. 6 (2016): 874–91. http://dx.doi.org/10.1177/0192623316649258.

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Terminal body weights (TBWs), thymus weight parameters, and thymus morphology were retrospectively evaluated in 453 cynomolgus monkeys assigned to control groups on nonclinical toxicity studies. Morphology of bone, ovary, and testis/epididymis were used to determine maturity status of individual animals. There was no correlation between TBW and thymus weight (absolute and/or relative to TBW or brain weight). Thymus weight parameters and grades of decreased lymphocytes in the thymus were highly variable in immature animals compared to mature animals. There was also high (up to 11-fold) variability of thymus weight parameters within a given control group on the same study (generally 3 or 4 animals per sex). Several parameters evaluated had more pronounced age-related changes in males when compared to females. Our results demonstrate the inherent variability of thymus weight parameters and morphologic observations for cynomolgus monkeys on toxicology studies. Changes in thymus parameters in cynomolgus monkeys are unreliable indicators of immunomodulation or immunotoxicity in the absence of other relevant findings. Therefore, the thymus parameters commonly evaluated in preclinical safety assessments should not be the primary data set used to determine the presence of a direct test article–related effect on the immune system.

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Dommergues, Jean-Louis, Bernard Laurin, and Christian Meister. "Evolution of ammonoid morphospace during the Early Jurassic radiation." Paleobiology 22, no. 2 (1996): 219–40. http://dx.doi.org/10.1017/s0094837300016183.

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The morphologic radiation of Early Jurassic ammonites following the near extinction at the end of the Triassic is analyzed from 436 species of 156 genera that form a representative sample of morphs occurring worldwide in the first three stages of the Jurassic (Hettangian, Sinemurian, Pliensbachian: 36 subzones, 24 m.y.). Morphologic diversity is analyzed independently of taxonomy by processing 18 shape parameters using multivariate analysis and clustering techniques. The morphospace thus defined indicates that morphs fall readily into two groups made up of four and five adjacent morpho-subsets. The temporal pattern of morphospace occupation in the 36 Lower Jurassic subzones displays diversification, depletion (sometimes total), and displacement of successive parts of the morphospace, reflecting a complex history in which morphologic radiation appears to be more than a process of diffusion. The history of the morphologic evolution is tentatively related to sea-level changes and there is a suggestion that morphologic diversity increases during second-order transgressive periods.

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Almeida, Jose C., Raissa P. Menezes, Selma A. Kuckelhaus, Anamelia L. Bocca, and Florencio Figueiredo. "Prognostic value of morphologic and clinical parameters in pT2 - pT3 prostate cancer." International braz j urol 33, no. 5 (2007): 662–72. http://dx.doi.org/10.1590/s1677-55382007000500007.

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Andea, A., D. C. Coit, and K. Busam. "An Analysis of Morphologic Parameters as Prognostic Markers in Merkel Cell Carcinoma." American Journal of Dermatopathology 28, no. 3 (2006): 228. http://dx.doi.org/10.1097/00000372-200606000-00014.

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Rampal, Virginie, Jérome Hausselle, Patricia Thoreux, Philippe Wicart, and Waffa Skalli. "Three-dimensional Morphologic Study of the Child’s Hip: Which Parameters Are Reproducible?" Clinical Orthopaedics and Related Research® 471, no. 4 (2012): 1343–48. http://dx.doi.org/10.1007/s11999-012-2660-5.

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Roig, José V., Julio Jordán, Juan García-Armengol, Pedro Esclapez, and Amparo Solana. "Changes in Anorectal Morphologic and Functional Parameters After Fistula-in-Ano Surgery." Diseases of the Colon & Rectum 52, no. 8 (2009): 1462–69. http://dx.doi.org/10.1007/dcr.0b013e3181a80e24.

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Journal articles on the topic 'Morphologic parameters'

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