Academic literature on the topic 'Morphological diagnostic'

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Journal articles on the topic "Morphological diagnostic"

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Losik, Ye A., L. S. Selivanova, T. V. Antonova, T. L. Lapina, A. S. Tertychny, and V. T. Ivashkin. "Morphological diagnostic criteria of autoimmune gastritis." Rossijskij žurnal gastroènterologii, gepatologii, koloproktologii 26, no. 5 (October 20, 2016): 13–20. http://dx.doi.org/10.22416/1382-4376-2016-5-13-20.

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ECTORS, N. L., M. F. DIXON, K. J. GEBOES, P. J. RUTGEERTS, V. J. DESMET, and G. R. VANTRAPPEN. "Granulomatous gastritis: a morphological and diagnostic approach." Histopathology 23, no. 1 (July 1993): 55–61. http://dx.doi.org/10.1111/j.1365-2559.1993.tb01183.x.

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Ellinidi, Vera N., Andrey A. Feoktistov, Aleksandra V. Lyamina, Diana M. Obidnyak, and Inna Y. Suvorova. "Chronic polypoid and lymphofollicular endometritis: hysteroscopic and histologycal diagnostic." Journal of obstetrics and women's diseases 66, no. 6 (December 15, 2017): 59–65. http://dx.doi.org/10.17816/jowd66659-65.

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Complex clinic-morphological study of uterine cavity scraping and a comparative hysteroscopic study of 964 women with infertility and unsuccessful IVF attemps were carried out. For the first time two prognostically meaningful clinic-morphological forms of chronic endometritis-polypoid and lymphofollicular are described. Specific features of their typical gradual morphogenesis and features of chronicity of diagnostic value are established. An algorithm for histological and hysteroscopic diagnostics is introduced.
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Surkova, L. K., G. L. Borodina, and N. S. Shpakovskaya. "Respiratory sarcoidosis: immunopathogenetic aspects and diagnostic problems." Proceedings of the National Academy of Sciences of Belarus, Medical series 16, no. 4 (December 5, 2019): 488–98. http://dx.doi.org/10.29235/1814-6023-2019-16-4-488-498.

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The analysis of the state of the problem on the sarcoidosis of the respiratory organs at the present stage has been carried out. The aspects of sarcouidosis immunopathogenesis are considered. Attention is focused on the variability of clinical and morphological manifestations and the expediency of identifying clinical and morphological phenotypes of sarcoidosis.In the differential diagnosis of tuberculosis and sarcoidosis, a comprehensive study of biopsy specimens is recommended, including a morphological study and a molecular study for mycobacterium tuberculosis. The negative result of a molecular study of a tissue substrate improves the accuracy and reliability of morphological verification of sarcoidosis.
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Venkatesh, Veenaa, Vinuta Malaichamy, and Vasanthan M. K. Vasanthan M K. "Morphological spectrum of lesions in renal biopsies with diagnostic role of Immunofluorescence." Annals of Pathology and Laboratory Medicine 6, no. 10 (October 25, 2019): A519–524. http://dx.doi.org/10.21276/apalm.2439.

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Bobrova, Vira I., Anastasia O. Horobets, Julia I. Proshchenko, Ludmila O. Levadna, and Zoriana V. Selska. "EOSINOPHILIC GASTRITIS IN CHILDREN: MORPHOLOGICAL AND IMMUNOHISTOCHEMICAL DIAGNOSTIC CRITERIA." Wiadomości Lekarskie 74, no. 7 (2021): 1722–27. http://dx.doi.org/10.36740/wlek202107129.

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The aim: To study peculiarities of morphological and immunohistochemical changes of stomach’s mucosa in eosinophilic gastritis in children Materials and methods: 64.1±6.0% patients with eosinophilic gastritis and 35.9±6.0% patients with lymphocytic gastritis participated in our investigation. In order to verify the diagnosis morphological and immunohistochemical diagnostics of the stomach’s mucosa was performed in all children. To assess morphological changes in tissues the specimens were colored with hematoxylin, eosin and picrofuchsin by van Gieson’s. Indirect streptavidin-peroxydase staining method was used for immunohistochemical investigation and the following indexes were assessed: proliferating cell nuclear antigen – PCNA, Bcl – 2, Вax, Collagen Type ІV, TGFβ and NF-κβ. Results: Comparative analysis of morphologic investigation has demonstrated that eosinophilic gastritis is characterized by fibrosis and fibroblasts proliferation into basal and superficial parts of mucosa’s lamina propria, multiple hemorrhages, thrombosis and erosions on the background of eosinophilic infiltration. Immunohistochemical indexes of cellular restoration in eosinophilic gastritis are characterized by increased proliferative activity and decreased indexes of proapoptotic and antiapoptotic activity. Prevalence of the reaction with the use of monoclonal antibodies to Collagen Type IV in majority of children with eosinophilic gastritis was characterized by separate fragmented foci in basal membranes of superficial epithelium. Remarkable TGFβ immune coloration was detected in majority of children on the background of fibrosis and eosinophilic infiltration of lamina propria. NF-κβ expression in epitheliocytes’ cytoplasm and nuclei was uneven. Homogenous remarkable coloration was detected in majority of patients with lymphocytic infiltration of mucosa. Conclusions: Eosinophilic gastritis course in children is characterized by remarkable inflammation, decreased regeneration of the mucosa, impairment of cellular restoration which is prognostic index of fibrous remodeling development.
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Saga, T., A. Shimatsu, K. Koizumi, T. Ichikawa, K. Yamamoto, S. Noguchi, R. Doi, et al. "Morphological imaging in the localization of neuroendocrine gastroenteropancreatic tumors found by somatostatin receptor scintigraphy." Acta Radiologica 46, no. 3 (May 2005): 227–32. http://dx.doi.org/10.1080/02841850510021003.

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Purpose: To evaluate the necessity of morphological images (MI) in reading somatostatin receptor scintigraphy (SRS) in patients with suspected neuroendocrine gastroenteropancreatic (GEP) tumors. Material and Methods: A Japanese multicenter clinical trial of SRS was conducted in 40 patients with suspected GEP tumors. Three experienced radiologists interpreted the images in three separate sessions in a blinded manner (1: SRS images alone, 2: MI alone, 3: SRS and MI analyzed simultaneously), and the reading results of each session were compared. In addition, the diagnostic abilities of SRS, MI and SRS alone and simultaneous SRS and MI readings were compared for patients where final diagnosis was obtained. Results: SRS detected more suspected lesions (positive or inconclusive uptake) than morphological images did (51 vs 27 lesions), but included many physiological uptakes detected as positive or inconclusive uptakes. Combined reading of SRS and morphological images helped to correctly recognize these physiological uptakes, and also helped in determining the anatomical localization of the abnormal uptakes. Combined reading of SRS and morphological images gave the highest diagnostic impact. Conclusion: The sensitivity of SRS with regard to GEP is high. However the specificity is very low. Morphologic imaging is necessary for the exclusion of physiological uptake and correct anatomic location of an abnormal tracer uptake. The combined reading of SRS and morphologic imaging studies gives the highest diagnostic impact.
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KARABACAK, OSMAN, HASAN YILDIRIM, and ESRA MARTİN. "Bellevalia pseudolongipes sp. nov. (Asparagaceae): a new species from southeastern Anatolia, Turkey." Phytotaxa 188, no. 4 (December 15, 2014): 209. http://dx.doi.org/10.11646/phytotaxa.188.4.3.

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Bellevalia pseudolongipes (Asparagaceae) is described and illustrated as a new species from Siirt province in South Eastern Anatolia, Turkey. Diagnostic morphological characters, a full description and detailed illustrations are provided. It is morphologically similar to B. longipes but easily differs in both several morphological characters and chromosome number. The somatic chromosome number was determined as 2n = 12 in B. pseudolongipes.
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Iryshkin, O. E., I. M. Iljinsky, O. M. Tsirulnikova, and S. V. Gautier. "CLINICAL AND MORPHOLOGICAL DIAGNOSTIC INTRAHEPATIC BILE DUCTS PAUCITY." Russian Journal of Transplantology and Artificial Organs 15, no. 2 (May 16, 2014): 56. http://dx.doi.org/10.15825/1995-1191-2013-2-56-64.

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Ziarkiewicz-Wróblewska, B., B. Górnicka, W. Suleiman, U. Ołdakowska-Jedynak, T. Wróblewski, M. Bogdańska, J. Ziółkowski, et al. "Posttransplant Lymphoproliferative Disorder: Morphological Picture and Diagnostic Difficulties." Transplantation Proceedings 38, no. 1 (January 2006): 168–72. http://dx.doi.org/10.1016/j.transproceed.2005.12.072.

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Dissertations / Theses on the topic "Morphological diagnostic"

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Ouma, Linda Achiengꞌ. "Synthesis, optical and morphological characterization of pbse quantum dots for diagnostic studies: a model study." Thesis, University of the Western Cape, 2013. http://hdl.handle.net/11394/3975.

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>Magister Scientiae - MSc
In this study PbSe quantum dots (QDs) were successfully synthesized via the organometallic and aqueous routes. Optical characterization was carried out using photoluminescence (PL) spectroscopy, structural and morphological characterization were carried out using X-ray diffraction (XRD) and transmission electron microscopy (TEM). Energy-dispersive X-ray spectroscopy (EDS) was used to determine the composition of the QDs. All the synthesized QDs were found to have emissions within the near-infrared region of the spectrum (≥1000 nm) with most of them being less than 5 nm in size. The aqueous synthesized QDs had a perfect Gaussian emission spectrum with a FWHM of ~23 nm indicating pure band gap emission and narrow size distribution respectively. The QDs were determined to have a cubic rock-salt crystal structure consistent with bulk PbSe. The aqueous synthesized QDs were however not stable in solution with the QDs precipitating after approximately 48 h. The organometallic synthesized QDs were transferred into the aqueous phase by exchanging the surface oleic acid ligands with 11-mercaptoundecanoic acid ligands. The ligand exchanged QDs were however stable in solution for over two weeks. The effects of reaction parameters on the optical and structural properties of the organometallic synthesized QDs were investigated by varying the reaction time, temperature, ligand purity, lead and selenium sources. It was observed that larger QDs were formed with longer reaction times, with reactions proceeding faster at higher reaction temperatures than at lower temperatures. Varying the ligand purity was found to have minimal effects on the properties of the synthesized QDs. The lead and selenium sources contributed largely to the properties of the QDs with lead oxide producing spherical QDs which were smaller compared to the cubic QDs produced from lead acetate. TBPSe was seen to produce smaller QDs as compared to TOPSe. The cytotoxity of the synthesized QDs was determined following the WST-1 cell viability assay with the QDs being found to be non-toxic at all the tested concentrations
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Chizhma, R. A., Soloviov N. O, Владислав Володимирович Сікора, Владислав Владимирович Сикора, Vladyslav Volodymyrovych Sikora, Артем Михайлович Піддубний, Артем Михайлович Поддубный, and Artem Mykhailovych Piddubnyi. "The role of psammoma bodies in the ovarian serous adenocarcinoma." Thesis, Sumy State University, 2020. https://essuir.sumdu.edu.ua/handle/123456789/81936.

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One of the current problems among women’s reproductive system diseases is ovarian tumors. Each year the risk of this disease shows a tendency to increase. The pathognomonic feature of the morphological diagnostic of ovarian cancer is Psammoma bodies (PBs), which are represented by plasticized calcium structures and are placed in the form of concentration circles. Should be noted, that the process of pathological biomineralization is most common in serous papillary carcinoma, but the mechanism of PBs formation is not fully understood yet.
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Panjwani, Priyadarshini Verfasser], and Roland [Gutachter] [Jahns. "Induction, Imaging, Histo-morphological and Molecular Characterization of Myocarditis in the Rat to Explore Novel Diagnostic Strategies for the Detection of Myocardial Inflammation / Priyadarshini Panjwani ; Gutachter: Roland Jahns." Würzburg : Universität Würzburg, 2016. http://d-nb.info/1120924731/34.

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Drury, Sarah L. "Molecular, morphological, and kinetic diagnosis of human preimplantation embryo vitality." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/88622/.

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There have been phenomenal advances in the field of reproductive medicine and success rates following in vitro fertilisation have improved dramatically in recent years. The aim of this project was to improve our understanding of human preimplantation embryo development by identifying potential markers of viability that may aid us in selecting the best embryo for uterine transfer in the clinical embryology laboratory. Investigations into the distribution of cytoskeletal F-actin in human embryos demonstrated that a highly organised actin cortex is important for embryo cleavage and continued development to the blastocyst stage. Whilst they are polarised in the mouse from the oocyte to the blastocyst, the regulatory proteins leptin and STAT3 are co-localised only at the oocyte stage in humans, and are distributed within different cytoplasmic domains in human cleavage stage embryos and blastocysts. Whether polarity in humans is predetermined in the oocyte remains elusive, but none of the evidence generated in this thesis supports this idea. Leptin transiently activates STAT3 via the long form of the leptin receptor, and most significantly in the ICM of human day 6 blastocysts. Morphological features of blastocysts that can be visualised microscopically, such as a double ICM and cytoplasmic projections connecting the ICM to the TE, provide clues to their viability and may help us to choose the most suitable embryo from a cohort when deciding which to transfer. Nuclear volumes may in future contribute to this selection. Using time lapse technology to study cleavage patterns is now a routine occurrence in the clinical embryology laboratory. The results in this thesis show that distinctive patterns of divisions and the site at which blastocysts hatch can provide us with more information than a snap-shot morphological evaluation. Finally, contributing to the development of modelling software and predictive algorithms for the study of human embryos, particularly in time lapse imaging, means that our understanding of this fascinating area of medicine will continue to progress.
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Dhinagar, Nikhil J. "Morphological Change Monitoring of Skin Lesions for Early Melanoma Detection." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1533911373953079.

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Crnalic, Sead. "Metastatic spinal cord compression in prostate cancer : clinical and morphological studies." Doctoral thesis, Umeå universitet, Ortopedi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-54461.

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Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. Criteria for identifying patients who may benefit from surgery are poorly defined. Most of the current knowledge regarding tumor biology in prostate cancer is based on studies of primary tumors or soft tissue metastases. The mechanisms regulating growth of bone metastases are not fully established. Aims: a) to evaluate outcome after surgery for MSCC in prostate cancer and to identify prognostic factors for survival and functional recovery; b) to evaluate current practice for referral of prostate cancer patients with MSCC; c) to analyze expression of androgen receptor (AR), cell proliferation, apoptosis, and prostate-specific antigen (PSA) in bone metastases with regard to survival after surgery for complications of bone metastases. Patients and Methods: We retrospectively evaluated the hospital records of 68 consecutive patients operated for metastatic spinal cord compression. Tumor tissue from bone metastases was obtained on spinal surgery (54 patients), fracture surgery (4 patients) and biopsy (2 patients), and analyzed by immunohistochemistry. Results: Study I: Mortality and complication rate after surgery was high. Patients with hormone-naïve disease and those with hormone-refractory disease with good performance status and without visceral metastases had more favorable survival. The ability to walk after surgery was related to better survival. Study II: A new score for prognosis of survival after surgery for spinal cord compression includes: hormone status of prostate cancer, Karnofsky performance status, evidence of visceral metastasis, and preoperative serum PSA. The score is simple, tumor specific, and easy to apply in clinical practice. Study III: Our results suggest that delays in diagnosis and treatment may have negative impact on functional outcome. Pretreatment ability to walk, hormone status of prostate cancer, and time from loss of ambulation influenced neurological recovery after surgery for spinal cord compression. Study IV: High nuclear AR immunostaining in bone metastases and high preoperative serum PSA were associated with a poor outcome after metastasis surgery in patients with hormone-refractory prostate cancer. Short-term effect of castration therapy disclosed that nuclear AR immunostaining was decreased and apoptosis was increased, but cell proliferation remained largely unaffected. Conclusion:  Prostate cancer patients with metastatic spinal cord compression represent a heterogeneous group. We identified prognostic factors for survival and functional outcome, which may help clinicians in making decisions about treatment. Our results also implicate the need for development of local and regional guidelines for treatment of patients with spinal cord compression, as well as the importance of information to patients at risk.
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Liuti, Tiziana. "Morphological assessment of paranasal sinuses and teeth in the horse." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33192.

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Sinonasal and dental diseases can be a serious disorder in horses due to the persistence of the former and the common extension of the latter to the supporting bones of the skull. The diagnosis of equine sinonasal and dental disease can be challenging due to the complexity of these and adjacent anatomical structures, and therefore the use of advanced imaging, including computed tomography (CT) has greatly increased recently. A major aim of this study was to improve the morphological characterization of the sinuses and cheek teeth in normal horses of different ages. These studies defined the volumes of the 7 different sinus compartments; showed that the volume of the different compartments increase with age; that in contrast to accepted findings, the Triadan 09 alveoli is located in the caudal maxillary sinus (CMS) in 13% of the youngest group and the Triadan 10 alveoli is fully within the rostral maxillary sinus (RMS) in 53% of cases. The infraorbital canal was found to be susceptible to apical infection-related damage in horses < 2 years of age (< 2 y.o.) due to the intimate relationship of this canal and the medial aspect of the maxillary cheek teeth alveoli. The mean positions of the clinical crowns and apices of the maxillary Triadan 11s were 2.48 cm (adjusted 5.2% of head height) and 2.83 cm (adjusted 6.2% of head height) more rostral, respectively in horses >16 y.o. compared to horses < 6 y.o., consistent with rostral dental drift. Measurements of dental drift could provide further objective radiographic guidelines on ageing horses by dental imaging and also help our understanding of the aetiopathogenesis of cheek teeth diastemata. This study also found that the reserve crown length decreased from a mean of 4.7 cm (adjusted 19.7% of head height) in the youngest (< 6y.o.) group of horses to a mean of 2.9 cm (adjusted 10.5% of head height) in the oldest group (>15y.o.), with the 06s and 09s having the shortest reserve crowns. These data are useful reference information for clinicians and radiologists in the diagnosis and treatment of equine sinonasal and dental disease. Morphological characterization of the ventral and dorsal conchal bullae in horses of different age using CT described the age-related difference in sizes of these structures (smaller in younger horses). In the ventral conchal bulla, this reduction in volume was probably related to protrusion of the large dental alveoli in young horses into the nasal cavity and bulla. Bullae linear measurements and volumes were also associated with head size. The anatomical position of both bullae was associated with specific maxillary cheek teeth, thus increasing the diagnostic value of conventional radiography in the investigation of bulla disease and providing landmarks for the surgical treatment of this disorder. Skull shape analyzed with the use of Procrustes statistical analysis showed landmark variability between different age groups and in particular, high landmark variability between young (< 5y.o.) and old (>16y.o.) horses and less landmark variability between adult (6-15y.o.) and old horses. Future studies could investigate changes in the equine skull in relation to genotype to characterize breed-related diseases affecting teeth and sinonasal compartments. In the second part of the study, 32 infected maxillary cheek teeth extracted from clinical cases were evaluated grossly and histologically and these pathological results were compared to the pre-extraction radiographic and CT imaging findings. This study showed a high sensitivity (97%) of CT in detecting changes in teeth affected by apical infection. In the third part of the study, 30 cheek teeth assessed as being abnormal based on oral, radiographic and CT examinations were extracted along with their alveoli from 27 cadaver heads. Gross and histological examination findings from these teeth and alveoli were compared to the pre-extraction imaging findings, again showed high sensitivity (96.4%) of CT in diagnosing cheek teeth apical infection. Additionally, CT showed a high correlation with histology in detecting dental infection related alveolar bone changes including alveolar bone lysis, sclerosis and bone thickening. This aspect of the study was also the second largest pathological study of equine apical infection published to date and thus has also improved our understanding of the pathogenesis of this disorder. In conclusion, CT was shown to be an excellent imaging modality for improving the morphological characterization of the sinuses and teeth in normal horses of different ages, and thus also improving the value of this modality in diagnosis and treatment of disease affecting sinonasal and dental structures. This study also objectively showed the high sensitivity of CT in detecting cheek teeth apical infection in horses as compared to radiography, including by assessment of alveolar bone changes. Overall, the results of this project improve morphological knowledge of the equine skull and teeth and will have direct clinical benefits by improving the diagnosis and thus the treatment of equine sinonasal and dental disease.
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Tovar, Perez Alexander Tovar. "Morphological evaluation of blastocyst after vitrification depending on treatment modality." Thesis, Uppsala universitet, Forskargrupper (Inst. för kvinnor och barns hälsa), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-366058.

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Assisted reproductive technology procedures has become a more complex treatment over the years after implementation of preimplantation genetic diagnostics and cryopreservation methods such as slow freeze and vitrification. When embryos undergo these methods they are exposed to external damage that threaten to affect their quality and thereby lead to lower survival rates and lower pregnancy rates. The aim of this study was to document blastocysts quality after vitrification, re-vitrification and preimplantation genetic diagnosis with subsequent vitrification. A total of 126 blastocysts were collected, of which 119 blastocysts were documented with the help of an experienced embryologists and the remaining seven blastocysts were from a new series of re-vitrified embryos. The 126 collected blastocyst were allocated into groups depending on their degree of preimplantation genetic diagnosis and vitrification. The gathered data was scoring according to morphology, expansion and proportion of necrotic cells at 2 and 4 hours of the expansion phase. Fisher exact test was used for statistical evaluation. There were no significant difference when comparing data before and after vitrification and preimplantation diagnosis, which indicates that these methods do not cause morphological damage to the blastocyst.
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Tunón, Ann-Marie. "The endometrium of the gynaecologically healthy mare during oestrus : a clinical, morphological, chemical and immunological study /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5407-7.pdf.

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Gawde, Purva R. "INTEGRATED ANALYSIS OF TEMPORAL AND MORPHOLOGICAL FEATURES USING MACHINE LEARNING TECHNIQUES FOR REAL TIME DIAGNOSIS OF ARRHYTHMIA AND IRREGULAR BEATS." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1544106866041632.

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Books on the topic "Morphological diagnostic"

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Gorczyca, Wojciech. Flow cytometry in neoplastic hematology: Morphologic-immunophenotypic correlation. London: Taylor & Francis, 2006.

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Lewis, S. M. Bench aids for the morphological diagnosis of anaemia. Geneva: World Health Organization, 2001.

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Pocket atlas of haematology: Morphological diagnosis for the clinician. Stuttgart: Thieme, 1985.

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Pocket atlas of hematology: Morphological diagnosis for the clinician. Stuttgart: Thieme, 1985.

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M, Altmannsberger, and Seifert Gerhard 1921-, eds. Morphological tumor markers: General aspects and diagnostic relevance. Berlin: Springer-Verlag, 1987.

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Seifert, Gerhard. Morphological Tumor Markers: General Aspects and Diagnostic Relevance (Current Topics in Pathology). Springer, 1988.

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Herder, W. W. de. Functional and Morphological Imaging of the Endocrine System. Springer, 2000.

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Cardim, Nuno, Denis Pellerin, and Filipa Xavier Valente. Hypertrophic cardiomyopathy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0042.

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Hypertrophic cardiomyopathy is a common inherited heart disease caused by genetic mutations in cardiac sarcomeric proteins. Although most patients are asymptomatic and many remain undiagnosed, the clinical presentation and natural history include sudden cardiac death, heart failure, and atrial fibrillation. Echocardiography plays an essential role in the diagnosis, serial monitoring, prognostic stratification, and family screening. Advances in Doppler myocardial imaging and deformation analysis have improved preclinical diagnosis as well as the differential diagnosis of left ventricular hypertrophy. Finally, echocardiography is closely involved in patient selection and in intraoperative guidance and monitoring of septal reduction procedures. This chapter describes the pathophysiology, clinical presentation, role of echocardiography, morphological features, differential diagnosis, diagnostic criteria in first-degree relatives, echo guidance for the treatment of symptomatic left ventricular outflow tract obstruction, and follow-up and monitoring of patients with hypertrophic cardiomyopathy.
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Roberts, Ian S. D., Philip Mason, and Agnes B. Fogo. The renal biopsy. Edited by Christopher G. Winearls. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0018.

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This chapter describes the indications for renal biopsy, the procedure, processing of the specimen and the diagnostic method applied by the nephropathologist, and illustrates the spectrum of pathologies seen. The terminology used in renal pathology is explained and illustrated. Diagnostic algorithms are presented. More detailed descriptions of the various pathologies, and in particular the rarer entities, are provided in specific chapters. The focus will be on native renal diseases. The renal biopsy is an invasive procedure associated with a risk of serious complications. The decision to perform a biopsy is based on a careful risk: benefit assessment. The final diagnosis is usually derived from combining clinical and histological data; it is therefore essential that the nephrologist includes all relevant information on the pathology request form. Discussion of the biopsy findings at a multidisciplinary meeting is an important part of the diagnostic and management decision-making process. The essential starting point for histological diagnosis is to define the morphological abnormality at light microscopy, the ‘pattern of disease’. In only a minority of cases will this be sufficient to provide a firm diagnosis; more frequently the morphology provides the basis for formulating a differential diagnosis. Supplemental information from immunohistology and electron microscopy, in addition to clinical, biochemical, and serological data, are used to reach a precise diagnosis. In addition to diagnosis, the renal biopsy may provide prognostic information and be used to guide therapy. For inflammatory renal diseases in particular, the biopsy report will include measures of disease activity and chronicity. In some instances the diagnosis may already be clear, and the biopsy is performed for grading and staging purposes or to assist in decisions about treatment.
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Kapural, Leonardo. Lumbar Disc Procedures: Fluoroscopy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0023.

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Discogenic lumbar pain is a frequent cause of prolonged disability. Currently, there are few effective minimally invasive therapeutic options to treat diseased discs and provide a long-term pain relief. Intradiscal biacuplasty improves functional capacity and affords pain relief in properly selected patients. Provocative discography is a relatively invasive intradiscal technique that has been used as a diagnostic tool to help to detect painful discs and associated morphological changes. One of the effective therapeutic approaches to control discogenic pain is to use an ablative radiofrequency intradiscal procedure, like biacuplasty. Intradiscal electrothermal therapy (IDET) is currently in limited use. Serious complications of intradiscal procedures are rather rare.
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Book chapters on the topic "Morphological diagnostic"

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Nishino, Kazuhiko, Takatoshi Sorimachi, and Yukihiko Fujii. "Diagnostic Evaluation: Morphological Imaging MRI." In Moyamoya Disease Update, 158–67. Tokyo: Springer Japan, 2010. http://dx.doi.org/10.1007/978-4-431-99703-0_24.

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Beger, H. G., and M. Büchler. "Outcome of Necrotizing Pancreatitis in Relation to Morphological Parameters." In Diagnostic Procedures in Pancreatic Disease, 130–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71128-2_20.

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Malfertheiner, P. "Combined Functional and Morphological Diagnostic Approach in Chronic Pancreatitis." In Diagnostic Procedures in Pancreatic Disease, 262–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71128-2_38.

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Kayser, Klaus, Janusz Szymas, and Ronald S. Weinstein. "Telepathology: The Technological Future of Diagnostic Morphological Procedures." In Telepathology, 97–150. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-60055-5_7.

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Malfertheiner, P., M. Büchler, A. Stanescu, and H. Ditschuneit. "Correlation of Morphological Lesions, Functional Changes, and Clinical Stages in Chronic Pancreatitis." In Diagnostic Procedures in Pancreatic Disease, 268–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71128-2_39.

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Madea, Burkhard, Michael Tsokos, and Johanna Preuß. "Death Due to Hypothermia Morphological Findings, their Pathogenesis and Diagnostic Value." In Forensic Pathology Reviews, 3–21. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-110-9_1.

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Schauer, A., D. Marx, I. Lipp, M. Schumacher, W. Sauerbrei, H. Rauschecker, and R. Sauer. "Diagnostic tools and prognostic factors in human breast cancer evaluated by morphological and immunohistochemical methods." In Breast Cancer: Biological and Clinical Progress, 255–76. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3494-5_19.

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Haque, Ziaul, and Mujeebur Rahman Khan. "Telotylenchidae: Tylenchorhynchus species." In Handbook of invasive plant-parasitic nematodes, 421–25. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789247367.0013.

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Abstract The stunt nematodes of the genus Tylenchorhynchus are obligate migratory root ectoparasites and belong to the family Telotylenchidae. This chapter includes the following information on Tylenchorhynchus: nomenclature; morphological and molecular diagnostic characteristics; geographical distribution; hosts; symptoms; biology and life cycle; economic importance; movement and means of dispersal; plant parts known to carry the nematode in trade/transport; plant parts not known to carry the nematode in trade/transport; pest risk analysis and looming threat from introduction; invasiveness rating; region-wise status of invasiveness; management measures; and phytosanitary measures.
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Syrjänen, Kari J. "Morphological Diagnosis." In Emerging Issues on HPV Infections, 157–64. Basel: KARGER, 2006. http://dx.doi.org/10.1159/000092749.

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Soslow, Robert A. "Morphologic Patterns." In Diagnostic Pathology of Ovarian Tumors, 1–9. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9751-7_1.

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Conference papers on the topic "Morphological diagnostic"

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Vogt III, Robert C., Gerald G. Fliss, and J. S. Mihocka. "Morphological processing of diagnostic radar images." In SPIE's 1996 International Symposium on Optical Science, Engineering, and Instrumentation, edited by Andrew G. Tescher. SPIE, 1996. http://dx.doi.org/10.1117/12.258222.

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van der Steen, A. F. W., Robert Huber, Gijs van Soest, Tianshi Wang, Tom Pfeiffer, Frits Mastik, Wolfgang Wieser, and Joost Daemen. "Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging." In Diagnostic and Therapeutic Applications of Light in Cardiology 2019, edited by Kenton W. Gregory and Laura Marcu. SPIE, 2019. http://dx.doi.org/10.1117/12.2506151.

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Zakaria, Nor Hisyamuddin, Anis Nurashikin Nordin, Maizirwan Mel, Sayeed M. Arifuzzaman, and Ioana Voiculescu. "MEMS Biosensor for Potential Cancer Cell Detection." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-10537.

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Typically, cancer diagnosis relies on morphological examination of surgically removed tissue samples. However, diagnosis based on morphological examination is difficult, not accurate and often requires large amounts of biological materials. Thus, additional more accurate markers are needed to further increase the diagnostic accuracy of cancer cells. Despite having similar morphological features, the cancer and normal cell populations show significantly different mechanical properties. The mechanical properties of cancer cells that have been identified as important factors for the diagnosis of cancer are the cell stiffness or elasticity and cell adhesion. We present an acoustic resonant platform that is used in liquid environments and it is able to monitor the attachment of normal and cancer cell lines. The biosensor is based on a MEMS sheer horizontal surface acoustic wave (SH-SAW) piezoelectric resonator. We consider the SH-SAW piezoelectric resonator because it is better suited for liquid sensing applications due to the minimal damping of the acoustic wave. The miniature size of this biosensor allows us to perform single cell electrical measurements which will provide information on the progression of cell adhesion, cell growth and viscoelasticity changes of normal and cancer cells. A commercial quartz crystal microbalance (QCM) is initially used to study the cell attachment process and correlate the relationship between the electrical measurements and the mechanical properties of cells. The commercial QCM could be used as a functional biosensor utilizing living cells as biological signal transduction elements.
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Omar, Mohamed, Alamgir Hossain, Li Zhang, and Hubert Shum. "An intelligent mobile-based automatic diagnostic system to identify retinal diseases using mathematical morphological operations." In 2014 8th International Conference on Software, Knowledge, Information Management and Applications (SKIMA). IEEE, 2014. http://dx.doi.org/10.1109/skima.2014.7083563.

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Vieira, Daniella Serafin Couto, Bráulio Leal Fernandes, Érica Elaine Traebert Simezo, Amanda Amaro Pereira, and Mara Scheffer. "STANDARDIZATION OF THE LABORATORY RESEARCH PROTOCOL AND ANATOMOPATHOLOGICAL DIAGNOSIS OF BREAST GRANULOMATOUS INJURIES." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1020.

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Introduction: Granulomatous breast lesions are multifactorial conditions, with clinical, mammographic, and ultrasound findings like those observed in cases of breast carcinoma. Histological evaluation can present key characteristics to define the lesion pattern. Although this entity is rarely reported in the literature, it is associated with inflammatory conditions such as Ductal Ectasia and foreign body reaction. However, it can also be associated with agents such as bacteria, fungi, and parasites. Furthermore, idiopathic causes and exclusion diagnosis, such as sarcoidosis, can be included in the etiology of the process. Objectives: To establish a correlation between the anatomopathological diagnosis and the laboratory investigation by culture for breast granulomatous lesions diagnosis, with validation of the sample’s analysis protocol. Methods: Samples were selected from 17 women treated at the Mastology Service of a Public Hospital in Brazil, with a history and physical examination that raised suspicion of breast granulomatous lesion and they had previous clinical indication of breast core biopsy. The collection of samples was guided by ultrasonography (USG). In turn, they were stored in a blood culture flask (BD BACTECTM) to perform culture tests by automation (VITEK2), bacterioscopy and fungi exams, and acid resistant bacillus (ARB) tests at the Laboratory of Clinical Analyses. Simultaneously, core biopsy samples, fixed in 10% buffered formaldehyde, were sent to a Laboratory of Pathological Anatomy, for a morphological evaluation and research of ARB, fungi, and other bacteria, using the Ziehl-Nielsen, Grocott, PAS and GRAM histochemical methods. Results: Of the 17 samples, 11 had a chronic inflammatory response pattern with a non-lobulocentric granulomatous reaction component and one of them had a lymphocytic mastitis pattern. The five patients with morphological pattern of lobulocentric granulomatous mastitis presented positive culture, four for Corynebacterium kroppenstedtil, and one for Staphylococcus hominis. Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value in this sample was 100%. Conclusion: The clinical and radiological aspects can bring difficulties that obscure the diagnostic and etiological interpretation of granulomatous lesions. Thus, the morphological details observed in the anatomical pathological examination and the use of the laboratory investigation protocol with standardization of histochemical reactions associated with the use of tools for microbiological diagnosis show increased sensitivity and specificity for the detection of specific etiologic agents in granulomatous mastitis.
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Vieira, Daniella Serafin Couto, Sandro Wopereis, Laura Otto Walter, and Maria Claudia Santos da Silva. "VALIDATION OF IMMUNOPHENOTYPING BY FLOW CYTOMETRY IN THE INVESTIGATION OF DIAGNOSTIC AND PROGNOSTIC MARKERS FOR BREAST CANCER." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1021.

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Introduction: Due to the high prevalence of breast cancer, it has a major financial impact on health systems. Currently, the diagnosis is made by morphological and immunohistochemical analysis (IHC). However, this methodology has some limitations. Therefore, methodologies capable of rapid and safe detection of tumor cells are needed, which can assist those already in use. Objectives: To validate immunophenotyping by flow cytometry (FC) in the investigation of diagnostic and prognostic markers for breast cancer; and to investigate lymphocytes subtypes infiltrated in the tumor and their relationship with tumor development. Methods: 52 breast tumor samples were sectioned and macerated in phosphatesaline buffer and stained with antibodies against estradiol (RE), progesterone (RP), HER2, Ki67, CD3, CD4, CD8 and CD45 receptors and analyzed by FC. All results were compared with IHC (reference method) in relation to sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV), except for Ki67, where bias was compared between methodologies and correlation between lymphocyte subtypes and tumor characteristics. Results: The comparison of the FC with the IHC for each marker presented the RE analysis (sensitivity: 75%, specificity: 90%, PPV: 96.7%, VPN: 47.4%); PR analysis (sensitivity: 72%, specificity: 70%, PPV: 79.3%, VPN: 60.8%); analysis of HER2 (sensitivity: 80%, specificity: 90.2%, PPV: 66.7%, VPN: 94.9%). The analysis of Ki67 by FC was shown to be equivalent to IHC, with the advantage of not having an observational bias. No correlations were observed between the molecular subtype intratumor lymphocyte population profile and the tumor histological grade. Conclusion: The results show the FC’s ability to safely and quickly detect breast cancer markers used in clinical practice. It is believed that the use of FC, in conjunction with morphological analysis and IHC, can overcome the individual limitations of each of the methodologies and provide reliable results in a faster and more efficient way, which will result in faster diagnoses and more accurate prognoses, directly benefiting patients.
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Li, Xia, Rongjun Cao, panpan Jia, and Chunxiang Liang. "The diagnostic value of aortic valve's morphological changes classification in subconal ventricular septal defect with double arterial stem." In International Conference on Medical Engineering and Bioinformatics. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/meb140681.

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Campbell, Ian C., Daiana Weiss, John N. Oshinski, and W. Robert Taylor. "Histological Determination of Murine Plaque Mechanics and Implications for Plaque Rupture." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19295.

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Among the most common models in atherosclerosis research is the atherosclerosis-prone mouse. Genetically manipulated mouse strains such as the ApoE−/− mouse will reliably form plaques under certain conditions, and these lesions have been noted to exhibit morphological and biochemical similarities with human atherosclerotic plaques. Unlike plaques in humans, however, murine plaques are not observed to rupture and form occlusive thrombi [1]. As atherosclerosis and its complications are the leading cause of death in the modern world, a comprehensive understanding of the mechanisms of plaque disruption is essential to develop diagnostic and interventional techniques. Although the mouse model is frequently employed to study plaque formation, its validity for studying plaque disruption events such as rupture or erosion has been questioned.
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Mozgaleva, N. V., P. A. Vedyapin, and Yu G. Parkhomenko. "MORPHOLOGICAL AND MOLECULAR-GENETIC VERIFICATION OF CORONAVIRUS INFECTION COVID-19 DURING AUTOPSY." In Molecular Diagnostics and Biosafety. Federal Budget Institute of Science 'Central Research Institute for Epidemiology', 2020. http://dx.doi.org/10.36233/978-5-9900432-9-9-157.

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Pan, Hongxia, Xin Xu, and Min Hu. "Morphological Diagnosis of High-speed Automaton Malfunction." In 2015 International Conference on Intelligent Systems Research and Mechatronics Engineering. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/isrme-15.2015.52.

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