Academic literature on the topic 'Motoneurones'

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Journal articles on the topic "Motoneurones"

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Büschges, A., J. Schmitz, and U. Bässler. "Rhythmic patterns in the thoracic nerve cord of the stick insect induced by pilocarpine." Journal of Experimental Biology 198, no. 2 (February 1, 1995): 435–56. http://dx.doi.org/10.1242/jeb.198.2.435.

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Bath application of the muscarinic agonist pilocarpine onto the deafferented stick insect thoracic nerve cord induced long-lasting rhythmic activity in leg motoneurones. Rhythmicity was induced at concentrations as low as 1x10(-4) mol l-1 pilocarpine. The most stable rhythms were reliably elicited at concentrations from 2x10(-3) mol l-1 to 5x10(-3) mol l-1. Rhythmicity could be completely abolished by application of atropine. The rhythm in antagonistic motoneurone pools of the three proximal leg joints, the subcoxal, the coxo-trochanteral (CT) and the femoro-tibial (FT), was strictly alternati
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Vrbova, G., R. Navarrete, and M. Lowrie. "Matching of muscle properties and motoneurone firing patterns during early stages of development." Journal of Experimental Biology 115, no. 1 (March 1, 1985): 113–23. http://dx.doi.org/10.1242/jeb.115.1.113.

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In adults, muscle fibres match the functional requirements of the motoneurone that supplies them. During early stages of postnatal development of the rat neither muscle fibre properties, nor activity patterns of motoneurones supplying fast and slow muscles have completed their differentiation. Nevertheless, even at this early stage of development the muscles have characteristic properties that are well matched to the activity patterns of immature motoneurones. With further development differentiation of motoneurone activity and muscle fibre properties goes hand in hand. If during this period o
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Kittmann, R. "Neural mechanisms of adaptive gain control in a joint control loop: muscle force and motoneuronal activity." Journal of Experimental Biology 200, no. 9 (January 1, 1997): 1383–402. http://dx.doi.org/10.1242/jeb.200.9.1383.

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An adaptive gain control system of a proprioceptive feedback system, the femur­tibia control loop, is investigated. It enables the joint control loop to work with a high gain but it prevents instability oscillations. In the inactive stick insect, the realisation of specific changes in gain is described for tibial torque, for extensor tibiae muscle force and for motoneuronal activity. In open-loop experiments, sinusoidal stimuli are applied to the femoral chordotonal organ (fCO). Changes in gain that depend on fCO stimulus parameters (such as amplitude, frequency and repetition rate), a
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COOKE, IAN R. C. "Further Studies of Crayfish Escape Behaviour: II. Giant Axon-Mediated Neural Activity in the Appendages." Journal of Experimental Biology 118, no. 1 (September 1, 1985): 367–77. http://dx.doi.org/10.1242/jeb.118.1.367.

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Stereotyped responses were evoked in a number of motoneurones in the appendages of semi-intact crayfish when the command neurones for escape behaviour were activated. The medial giant neurones mediated short latency responses in pereiopod common inhibitor, promotor and extensor motoneurones, several abdominal first root neurones and one uropod exopodite promotor motoneurone. The lateral giant neurones mediated short latency responses in the pereiopod common inhibitor neurones, the same abdominal first root neurones and one uropod protopodite promotor motoneurone. These responses can be correla
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Gardiner, Phillip, Eric Beaumont, and Bruno Cormery. "Motoneurones "Learn" and "Forget" Physical Activity." Canadian Journal of Applied Physiology 30, no. 3 (June 1, 2005): 352–70. http://dx.doi.org/10.1139/h05-127.

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In spite of our knowledge of activity related adaptations in supraspinal neurones and skeletal muscles, very little is known concerning adaptations in α-motoneurones to alterations in chronic activity levels. Recent evidence shows that the biophysical properties of α-motoneurones are plastic and adapt to both increases and decreases in chronic activation. The nature of the adaptations-in resting membrane potential, spike threshold, afterhyperpolarization amplitude, and rate of depolarization during spike generation-point to involvement of density, type, location, and/or metabolic modulation of
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Neuman, R. S. "Action of serotonin and norepinephrine on spinal motoneurones following blockade of synaptic transmission." Canadian Journal of Physiology and Pharmacology 63, no. 6 (June 1, 1985): 735–38. http://dx.doi.org/10.1139/y85-120.

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The actions of serotonin and norepinephrine were investigated on spinal motoneurones in isolated, hemisected rat and frog spinal cords. Serotonin and norepinephrine induced slowly developing depolarizations of spinal motoneurones which were frequently preceded by brief, low amplitude hyperpolarizations. Neither the depolarizations nor the hyperpolarizations were attenuated by 20 mM Mg2+ or tetrodotoxin, although synaptic transmission was blocked in both cases. It thus appears unlikely that the action of serotonin and norepinephrine on spinal motoneurone polarization and results from an indirec
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Russell, D. F. "Neural basis of teeth coordination during gastric mill rhythms in spiny lobsters, Panulirus interruptus." Journal of Experimental Biology 114, no. 1 (January 1, 1985): 99–119. http://dx.doi.org/10.1242/jeb.114.1.99.

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Motoneurones that drive the closing of the lateral teeth during gastric mill rhythms in spiny lobsters start firing before the motoneurones that drive the medial tooth powerstroke. This has the expected behavioural interpretation that the lateral teeth must close on a food particle before the medial tooth is pulled across it. The neural basis of the teeth coordination was examined. Experiments were made during gastric rhythms in in vitro preparations comprising the stomatogastric, oesophageal and (paired) commissural ganglia. Identified neurones in the stomatogastric ganglion were polarized to
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Sears, T. A. "Structural changes in intercostal motoneurones following axotomy." Journal of Experimental Biology 132, no. 1 (September 1, 1987): 93–109. http://dx.doi.org/10.1242/jeb.132.1.93.

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Motoneurone disease (MND or amyotrophic lateral sclerosis) is a paralysing disease of unknown cause involving progressive, widespread muscle atrophy due to degeneration of spinal and other motoneurones and an accompanying loss of Betz cells in the motor cortex. A current hypothesis attributes the disease to the loss of a muscle-derived neurotrophic factor acting in concert with the normal age-related deterioration and loss of motoneurones. The roots of this hypothesis are traced through research based mainly on the developing neuromuscular system, and in particular on the age-related processes
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Ferguson, G. P., and P. R. Benjamin. "The whole-body withdrawal response of Lymnaea stagnalis. II. Activation of central motoneurones and muscles by sensory input." Journal of Experimental Biology 158, no. 1 (July 1, 1991): 97–116. http://dx.doi.org/10.1242/jeb.158.1.97.

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The role of centrally located motoneurones in producing the whole-body withdrawal response of Lymnaea stagnalis (L.) was investigated. The motoneurones innervating the muscles used during whole-body withdrawal, the columellar muscle (CM) and the dorsal longitudinal muscle (DLM) were cells with a high resting potential (−60 to −70 mV) and thus a high threshold for spike initiation. In both semi-intact and isolated brain preparations these motoneurones showed very little spontaneous spike activity. When spontaneous firing was seen it could be correlated with the occurrence of two types of sponta
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Murayama, M., and M. Takahata. "Neuronal mechanisms underlying the facilitatory control of uropod steering behaviour during treadmill walking in crayfish. I. Antagonistically regulated background excitability of uropod motoneurones." Journal of Experimental Biology 201, no. 9 (May 1, 1998): 1283–94. http://dx.doi.org/10.1242/jeb.201.9.1283.

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One of the postural reflexes of crayfish, the uropod steering response, is elicited by specific sensory inputs while the animal is walking. It is not elicited, however, by the same inputs when the animal is at rest. To clarify the neuronal mechanisms underlying this facilitatory control of body posture in the active animals, we used intracellular recordings to analyse the synaptic activities of uropod motor system neurones in an unanaesthetized whole-animal preparation. Several uropod motoneurones were found to receive sustained depolarizing inputs during walking, whereas the walking leg moton
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Dissertations / Theses on the topic "Motoneurones"

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Fuente, Ruiz Sandra de la. "Development of new therapeutic strategies for Spinal Muscular Atrophy." Doctoral thesis, Universitat de Lleida, 2020. http://hdl.handle.net/10803/669753.

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L'Atròfia Muscular Espinal (AME) és una malaltia neurodegenerativa greu i la primera causa genètica de mort infantil. S'origina per la pèrdua o mutació del gen Survival Motor Neuron 1 (SMN1) que causa una deficiència de la proteïna de Survival Motor Neuron (SMN). La reducció d'aquesta proteïna condueix principalment a la degeneració de les motoneurones (MNs) de la medul·la espinal i, en conseqüència, produeix atròfia i feblesa del múscul esquelètic. Actualment, només es coneix parcialment quins mecanismes cel·lulars i moleculars exactes són els responsables de la pèrdua de funció de les MNs. L
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Sedel, Frédéric. "Mécanisme de programmation de la mort des motoneurones embryonnaires." Paris 6, 2005. http://www.theses.fr/2005PA066611.

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Sahal, Anil. "The monoaminergic control of gamma motoneurones." Thesis, University of Glasgow, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394767.

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Leroy, Félix. "Atteinte différentielle de deux populations de motoneurones spinaux chez le souriceau SOD1 G93A (modèle de la maladie de Charcot)." Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05T063/document.

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La deuxième semaine qui suit la naissance est critique pour le développement du système locomoteur de la souris. C’est pendant cette semaine que les souriceaux acquièrent leur posture et commencent à marcher. Cette transformation implique une réorganisation en profondeur des éléments composant les unités motrices. Cependant, nous ne savons encore que peu de choses sur la différenciation des propriétés intrinsèques des motoneurones innervant les fibres musculaires. Contrairement à l’adulte, où la décharge démarre au début de la stimulation, les motoneurones de souriceaux déchargent de façon hét
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Teixidó, Viyuela Laura. "Factors sèrics en l’Esclerosi Lateral Amiotròfica. Modulació del receptor de glutamat de tipus NMDA GluN1/GluN2A." Doctoral thesis, Universitat de Barcelona, 2011. http://hdl.handle.net/10803/79039.

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L’Esclerosi Lateral Amiotròfica (ELA o ALS) és una malaltia neuromuscular caracteritzada per la degeneració selectiva de les motoneurones (MN) superiors e inferiors del còrtex motor, el tronc de l’encèfal i la medul•la espinal, que resulta en una debilitat, espasticitat i atròfia progressives de la musculatura. Menys del 10% dels casos corresponen a la forma familiar de la malaltia, i un 20% d’aquests estan relacionats a mutacions en el gen de l’enzim superòxid dismutasa 1 (mSOD1). La resta de casos corresponen a la forma esporàdica. Les causes implicades en la degeneració selectiva de les MN
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Bouhadfane, Mouloud. "Propriétés électriques bistables des motoneurones de la moelle épinière : Identification des mécanismes ioniques sous-jacents." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM5030/document.

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La posture, composante statique du contrôle moteur permettant une position érigée du corps, repose sur une décharge tonique des motoneurones innervant nos muscles antigravitaires. La décharge prend la forme de « potentiel de plateau » au niveau de motoneurones matures chez de nombreux vertébrés. Pour déterminer une éventuelle concordance entre l'émergence des propriétés de plateau et le développement postural, notre travail a eu pour but d'étudier la maturation et la nature ionique des potentiels de plateau des motoneurones innervant le muscle triceps surae (extenseur de la cheville) chez le r
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SIMON, MAGDA. "Developpement postnatal des motoneurones spinaux lombaires du chat : identification des motoneurones alpha et gamma et remaniements de leur equipement synaptique." Paris 6, 1996. http://www.theses.fr/1996PA066391.

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Dans la moelle lombaire de chat adulte, deux populations de motoneurones se distinguent par leur cible musculaire: les motoneurones alpha et gamma. Dans ce travail, les questions suivantes ont ete abordees: 1) les motoneurones sont-ils des la naissance identifiables comme alpha ou gamma ? pour repondre a cette question, nous avons utilise les criteres ultrastructuraux d'identification etablis chez le chat adulte. 2) comment l'equipement synaptique des motoneurones est-il remanie pendant le developpement postnatal ? dans une premiere etape, nous avons examine en microscopie electronique les mot
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Allard, Ludivine. "Dysfonctions mitochondriales et homéostasie bioénergétique des motoneurones dans un modèle de sclérose latérale amyotrophique." Thesis, Bordeaux 2, 2013. http://www.theses.fr/2013BOR22088/document.

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La sclérose latérale amyotrophique (SLA) est une maladie neurodégénérative fatale de l'âge adulte, caractérisée par une perte de motoneurones, conduisant à une atrophie et une faiblesse musculaires. Des mutations de la superoxyde dismutase-1 (SOD1) provoquent une forme génétique de SLA. Comme chez les patients atteints de SLA, le modèle animal de SLA, SOD1 mutant, révèle que tous les motoneurones sont inégalement sensibles à l'évolution de la maladie. Les mitochondries, centrales énergétiques des cellules, sont des organelles précocement touchées dans la pathologie de la SLA. Un mécanisme attr
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Conway, Elizabeth Ann. "The development of corticospinal projections in man." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296148.

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Evans, Pamela. "Crossed reflexes of the human lower limbs : a study using the Hoffman reflex." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367596.

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Books on the topic "Motoneurones"

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O'Donovan, Michael J., and Mélanie Falgairolle, eds. Vertebrate Motoneurons. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07167-6.

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Imaharu, Nakano, and Hirano Asao 1926-, eds. Amyotrophic lateral sclerosis: Progress and perspectives in basic research and clinical application : proceedings of the 11th Tokyo Metropolitan Institute for Neuroscience (TMIN) International Symposium, Tokyo, October 25-27, 1995. Amsterdam: Elsevier Science, 1996.

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A, Wernig, ed. Plasticity of motoneuronal connections. Amsterdam: Elsevier, 1991.

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Stewart, Bryan A. Synaptic plasticity in a regenerated crayfish phasic motoneuron. Ottawa: National Library of Canada, 1992.

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Krammer, Eva B., Martin F. Lischka, Thomas P. Egger, Maria Riedl, and Helmut Gruber. The Motoneuronal Organization of the Spinal Accessory Nuclear Complex. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-10362-3.

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1944-, Krammer E. B., ed. The Motoneuronal organization of the spinal accessory nuclear complex. Berlin: Springer-Verlag, 1987.

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Orth, Peter M. R. Phosphorylation-dependent plasticity at synapses of a crayfish phasic motoneuron. Ottawa: National Library of Canada, 2002.

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Patel, Varsha. Neuromuscular synaptic differentiation of a crab motoneuron in four separate muscles. Ottawa: National Library of Canada, 1996.

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Hirji, Rahim. Structure of regenerated synaptic connections of allotransplanted phasic motoneurons on a tonic muscle in crayfish. Ottawa: National Library of Canada, 1999.

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Campbell, Jessica J. An investigation into factors affecting motoneuron regeneration in the rat sciatic nerve. Ottawa: National Library of Canada, 1990.

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Book chapters on the topic "Motoneurones"

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Brock, L. G., J. S. Coombs, and J. C. Eccles. "Antidromic Propagation of Impulses into Motoneurones." In Ciba Foundation Symposium - The Spinal Cord, 120–31. Chichester, UK: John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718827.ch11.

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Mendell, Lorne M. "Synaptic Differentiation on Type Identified Motoneurones." In Alpha and Gamma Motor Systems, 3–8. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1935-5_1.

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Alaburda, Aidas, Jean-François Perrier, and Jørn Hounsgaard. "Mechanisms Causing Plateau Potentials in Spinal Motoneurones." In Advances in Experimental Medicine and Biology, 219–26. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0713-0_27.

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Kutsch, W., and R. Heckmann. "Homologous structures, exemplified by motoneurones of Mandibulata." In Experientia Supplementum, 221–48. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-9219-3_11.

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Awiszus, Friedemann, and Helmut Feistner. "The “Size Principle” of Human α-Motoneurones." In Alpha and Gamma Motor Systems, 65–70. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1935-5_14.

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Collins, David F., Monica Gorassini, David Bennett, David Burke, and Simon C. Gandevia. "Recent Evidence for Plateau Potentials in Human Motoneurones." In Advances in Experimental Medicine and Biology, 227–35. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0713-0_28.

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Johnson, I. P., Y. S. Simaika, and T. A. Sears. "Synaptic Loss from Axotomised α- and γ-Motoneurones." In Alpha and Gamma Motor Systems, 51–53. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1935-5_10.

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Skorupski, P. "Central and Reflex Recruitment of Crayfish Leg Motoneurones." In Neural Control of Movement, 261–68. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-1985-0_32.

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Sears, T. A., I. P. Johnson, and A. H. Pullen. "Ultrastructural Analysis of Target-Dependent Properties of Mammalian Motoneurones." In Advances in Applied Neurological Sciences, 143–50. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71540-2_16.

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Kernell, Daniel. "Things We Know and Do Not Know About Motoneurones." In Advances in Experimental Medicine and Biology, 187–92. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0713-0_22.

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Conference papers on the topic "Motoneurones"

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Leão, Arthur Ventura Martins, Alexandre Leite Rodrigues de Oliveira, and Luciana Politti Cartarozzi. "Neuroprotection by memantine after compressive spinal root lesion." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.383.

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Introduction: Compressive root lesions are characterized by changes in the spinal cord microenvironment, which include motoneuron chromatolysis and degeneration, chronic gliosis, and glutamatergic excitotoxicity. Since excessive NMDAr stimulation by glutamate leads to neuronal degeneration, the use of NMDAr antagonists has been proposed as a promissing treatment central and peripheral nerve injuries. Objective: The present study aimed to investigate the neuroprotective effects of memantine, following compressive spinal root axotomy. Methods: Adult C57BL/6J mice were subjected to unilateral ven
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Serradori, Massimiliano, Marco Gherardi, Luciano Gabbrielli, Claudio Bettini, Ferruccio Aquilini, Giovanni D'Ambrosio, Antonio Servino, and Alessandro Celi. "Prognostic determinants in motoneuron diseases." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1907.

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Shapiro, Nicholas P., and Robert H. Lee. "Synaptic Amplification in Motoneurons: Computational and Mechanistic Implications." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.260838.

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Shapiro, Nicholas P., and Robert H. Lee. "Synaptic Amplification in Motoneurons: Computational and Mechanistic Implications." In Conference Proceedings. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2006. http://dx.doi.org/10.1109/iembs.2006.4397474.

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Gamal, Mai, Mohamed H. Mousa, Seif Eldawlatly, and Sherif M. Elbasiouny. "Automated Cell-Type Classification and Death-Detection of Spinal Motoneurons." In 2018 9th Cairo International Biomedical Engineering Conference (CIBEC). IEEE, 2018. http://dx.doi.org/10.1109/cibec.2018.8641824.

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Chmykhova, Nadezhda, Natalia Kalinina, Aleksey Zaitsev, and Nikolai Vesselkin. "MODULATION OF LUMBAR MOTONEURONS ACTIVITY BY METABOTROPIC GLUTAMATE AND SEROTONIN RECEPTORS." In XV International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m620.sudak.ns2019-15/457.

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Yao Li, L. H. Smith, L. J. Hargrove, D. J. Weber, and G. E. Loeb. "Estimation of excitatory drive from sparse motoneuron sampling." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346752.

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Mousa, Mohamed H., Ahmed H. Kandil, and Sherif M. Elbasiouny. "Simulation of dendritic L-type ca channels' warm-up phenomenon in spinal motoneurons." In 2016 8th Cairo International Biomedical Engineering Conference (CIBEC). IEEE, 2016. http://dx.doi.org/10.1109/cibec.2016.7836113.

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Suresh, A. K., Xiaogang Hu, R. K. Powers, and W. Z. Rymer. "Examination of afterhyperpolarization duration changes in motoneurons innervating paretic muscles in stroke survivors." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346740.

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Cisi, Rogerio R. L., and Andre F. Kohn. "H-reflex depression simulated by a biologically realistic motoneuron network." In 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2007. http://dx.doi.org/10.1109/iembs.2007.4352889.

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