Academic literature on the topic 'Mouse leukemia viruses'

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Journal articles on the topic "Mouse leukemia viruses"

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Changolkar, Lakshmi N., Geetika Singh, and John R. Pehrson. "macroH2A1-Dependent Silencing of Endogenous Murine Leukemia Viruses." Molecular and Cellular Biology 28, no. 6 (2008): 2059–65. http://dx.doi.org/10.1128/mcb.01362-07.

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ABSTRACT We show that macroH2A1 histone variants are important for repressing the expression of endogenous murine leukemia viruses (MLVs) in mouse liver. Intact MLV proviruses and proviruses with deletions in env were nearly silent in normal mouse liver and showed substantial derepression in macroH2A1 knockout liver. In contrast, MLV proviruses with a deletion in the 5′ end of pro-pol were expressed in normal liver and showed relatively low levels of derepression in knockout liver. macroH2A1 nucleosomes were enriched on endogenous MLVs, with the highest enrichment occurring on the 5′ end of pr
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Cingöz, Oya, and John M. Coffin. "Endogenous Murine Leukemia Viruses: Relationship to XMRV and Related Sequences Detected in Human DNA Samples." Advances in Virology 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/940210.

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Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as endogenous proviruses in mouse genomes. Here, we review the relationship of the human and mouse virus isolates and discuss the potential complications associated with the detection of MLV-like sequences from clinical samples.
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Sanchez-Martinez, Silvia, Amanda L. Aloia, Demetria Harvin, et al. "Studies on the Restriction of Murine Leukemia Viruses by Mouse APOBEC3." PLoS ONE 7, no. 5 (2012): e38190. http://dx.doi.org/10.1371/journal.pone.0038190.

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Jung, Yong Tae, Tiyun Wu, and Christine A. Kozak. "Characterization of Recombinant Nonecotropic Murine Leukemia Viruses from the Wild Mouse Species Mus spretus." Journal of Virology 77, no. 23 (2003): 12773–81. http://dx.doi.org/10.1128/jvi.77.23.12773-12781.2003.

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ABSTRACT The wild mouse species most closely related to the common laboratory strains contain proviral env genes of the xenotropic/polytropic subgroup of mouse leukemia viruses (MLVs). To determine if the polytropic proviruses of Mus spretus contain functional genes, we inoculated neonates with Moloney MLV (MoMLV) or amphotropic MLV (A-MLV) and screened for viral recombinants with altered host ranges. Thymus and spleen cells from MoMLV-inoculated mice were plated on Mus dunni cells and mink cells, since these cells do not support the replication of MoMLV, and cells from A-MLV-inoculated mice w
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Bamunusinghe, Devinka, Zohreh Naghashfar, Alicia Buckler-White, et al. "Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice." Journal of Virology 90, no. 8 (2016): 4186–98. http://dx.doi.org/10.1128/jvi.03186-15.

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ABSTRACTMouse leukemia viruses (MLVs) are found in the common inbred strains of laboratory mice and in the house mouse subspecies ofMus musculus. Receptor usage and envelope (env) sequence variation define three MLV host range subgroups in laboratory mice: ecotropic, polytropic, and xenotropic MLVs (E-, P-, and X-MLVs, respectively). These exogenous MLVs derive from endogenous retroviruses (ERVs) that were acquired by the wild mouse progenitors of laboratory mice about 1 million years ago. We analyzed the genomes of seven MLVs isolated from Eurasian and American wild mice and three previously
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Jung, Yong Tae, and Christine A. Kozak. "A Single Amino Acid Change in the Murine Leukemia Virus Capsid Gene Responsible for theFv1nr Phenotype." Journal of Virology 74, no. 11 (2000): 5385–87. http://dx.doi.org/10.1128/jvi.74.11.5385-5387.2000.

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ABSTRACT The nr allele at the mouse Fv1 restriction locus governs resistance to B-tropic and some N-tropic murine leukemia viruses (MLVs). Sequence analysis and site-specific mutagenesis of N-tropic MLVs identified a single amino acid difference responsible for this restriction that is distinct from the site that governs N or B tropism. Viruses with other substitutions at this site were evaluated for altered replication patterns.
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Tomonaga, Keizo, and John M. Coffin. "Structure and Distribution of Endogenous Nonecotropic Murine Leukemia Viruses in Wild Mice." Journal of Virology 72, no. 10 (1998): 8289–300. http://dx.doi.org/10.1128/jvi.72.10.8289-8300.1998.

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ABSTRACT Virtually all of our present understanding of endogenous murine leukemia viruses (MLVs) is based on studies with inbred mice. To develop a better understanding of the interaction between endogenous retroviruses and their hosts, we have carried out a systematic investigation of endogenous nonecotropic MLVs in wild mice. Species studied included four major subspecies of Mus musculus(M. m. castaneus, M. m. musculus, M. m. molossinus, and M. m. domesticus) as well as four common inbred laboratory strains (AKR/J, HRS/J, C3H/HeJ, and C57BL/6J). We determined the detailed distribution of non
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Akaogi, Jun, Dina C. Nacionales, Yoshiki Kuroda, Westley H. Reeves, and Minoru Satoh. "Ecotropic murine leukemia viruses and exogenous mouse mammary tumor viruses are not essential for pristane-induced lupus." Arthritis & Rheumatism 48, no. 10 (2003): 2990–92. http://dx.doi.org/10.1002/art.11314.

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Tipper, Christopher H., Craig E. Bencsics, and John M. Coffin. "Characterization of Hortulanus Endogenous Murine Leukemia Virus, an Endogenous Provirus That Encodes an Infectious Murine Leukemia Virus of a Novel Subgroup." Journal of Virology 79, no. 13 (2005): 8316–29. http://dx.doi.org/10.1128/jvi.79.13.8316-8329.2005.

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ABSTRACT Simple retroviruses present a unique opportunity for examining the host-virus relationship. Following exogenous infection and integration into the germ line, copies of these viruses can become fixed within the genome. The resulting endogenous proviral “fossils” represent a record of past retroviral infections and forms. Previous work in our laboratory has been directed at dissecting the extensive nonecotropic murine leukemia virus content of the mouse genome. One such provirus, hortulanus endogenous murine leukemia virus (HEMV), found in a single copy in the genome of Mus spicilegus,
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Bamunusinghe, Devinka, Matthew Skorski, Alicia Buckler-White, and Christine Kozak. "Xenotropic Mouse Gammaretroviruses Isolated from Pre-Leukemic Tissues Include a Recombinant." Viruses 10, no. 8 (2018): 418. http://dx.doi.org/10.3390/v10080418.

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Naturally-occurring lymphomagenesis is induced by mouse leukemia viruses (MLVs) carried as endogenous retroviruses (ERVs). Replicating the ecotropic MLVs recombines with polytropic (P-ERVs) and xenotropic ERVs (X-ERVs) to generate pathogenic viruses with an altered host range. While most recovered nonecotropic recombinants have a polytropic host range, the X-MLVs are also present in the pre-leukemic tissues. We analyzed two such isolates from the AKR mice to identify their ERV progenitors and to look for evidence of recombination. AKR40 resembles the active X-ERV Bxv1, while AKR6 has a Bxv1-li
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Dissertations / Theses on the topic "Mouse leukemia viruses"

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Najmabadi, Hossein. "Characterization of the Self-Replicating Kirsten Murine Leukemia Viral DNA: Replication and Tetracycline Resistance." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc798479/.

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This research project deals with the characterization of self-replicating Kirsten murine viral DNA. The replication of this viral DNA and tetracycline resistance conferred to bacteria by this viral DNA will be studied. The restriction endonuclease and Southern blot analysis revealed a fragment of pBR322 from the Hind III and Pst I site that is located in the 3' end of the MLV-K:E molecule. Single stranded sequencing of the two terminal ends of this fragment verified that the 3' end of MLV-K:E contains identical sequence homology to pBR322. The presence of this pBR322 fragment explains the unus
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BOI, STEFANO. "Differential effects of mouse APOBEC3 after incorporation into murine leukemia viruses." Doctoral thesis, Università degli Studi di Cagliari, 2014. http://hdl.handle.net/11584/266459.

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APOBEC3 proteins are cytidine deaminases that are potent inhibitors of retrovirus replication. These restriction factors induce G→A hypermutation as a result of deamination of cytidine in the single stranded transcripts generated by reverse transcription during replication. Mouse APOBEC3 (mA3) effectively inhibits the replication of endogenous retroelements whereas most exogenous murine leukemia viruses (MuLV) are largely resistant to the action(s) of mA3. However, several studies have reported significant inhibition of infectivity by virion-associated mA3 that did not appear to be the result
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Kabdulov, Timur O. "Mechanisms of retroviral replication." Morgantown, W. Va. : [West Virginia University Libraries], 2001. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=2256.

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Nardiello, Tricia Lynn. "Protease activity in lymphoid organs of BALB/C and C57BL/6 mice following murine leukemia virus /." Connect to online version, 2007. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2007/214.pdf.

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Halvas, Elias Konstantine. "Structural determinants of murine leukemia virus (MLV) reverse transcriptase (RT) important for fidelity and drug-resistance in vivo." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1518.

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Thesis (Ph. D.)--West Virginia University, 2000.<br>Title from document title page. Document formatted into pages; contains x, 231 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 188-203).
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Socha, Amanda L. "Differential expression of an endogenous retrovirus in MAIDS susceptible (C57BL/6) versus resistant (BALB/C) mice /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2006/159.pdf.

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Krauchunas, Amber R. M. "CD8⁺ T-cell response potential, as determined by expression of the high affinity interleukin-2 receptor, in murine AIDS /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/www/2006/149.pdf.

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Haworth, Richard Ian. "The role of macrophage scavenger receptors in host defence : studies in normal and genetically deficient murine models." Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:cc184f02-1393-407c-b241-a44ab3e0215c.

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Voronin, Yegor A. "Investigation of initiation of reverse transcription in retroviruses using vectors with two primer-binding sites." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=3136.

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Berjanskii, Mark. "Structure and dynamics of the N-terminal J-domain of T antigens of murine polyomavirus." MU online access free, to others for fee Free online access, 2002. http://wwwlib.umi.com/cr/mo/preview?3052146.

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Books on the topic "Mouse leukemia viruses"

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Farone, Mary Bosch. Infection and tumorigenicity of murine tumor cells following in vitro treatment with reovirus. 1989.

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Ulm, Jacob W. Elucidation of retroviral capsid residues involved in modulation of murine and human cell post-entry restriction. 2006.

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Book chapters on the topic "Mouse leukemia viruses"

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Nexø, B. A. "The Biology of Endogenous Leukemia Viruses: A Study of the DBA/2 Mouse." In International Symposium: Retroviruses and Human Pathology. Humana Press, 1985. http://dx.doi.org/10.1007/978-1-4612-5008-1_5.

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Al, E. J. M., T. Jorritsma, A. Blok, H. M. G. Sillekens, and P. C. van Mourik. "Significance of Multiple Testing on Murine Leukemia Virus of Mouse Hybridomas." In New Developments and New Applications in Animal Cell Technology. Springer Netherlands, 1998. http://dx.doi.org/10.1007/0-306-46860-3_86.

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Vasmel, W. L. E., M. Zijlstra, R. E. Y. De Goede, H. J. Schoenmakers, T. Radaszkiewics, and C. J. M. Melief. "The Major Histocompatibility Complex (H-2) of the Mouse Influences the Phenotype of Murine Leukemia Virus-Induced Lymphomas." In International Symposium: Retroviruses and Human Pathology. Humana Press, 1985. http://dx.doi.org/10.1007/978-1-4612-5008-1_11.

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Morse, H. C. "Mouse Leukemia Viruses." In Encyclopedia of Genetics. Elsevier, 2001. http://dx.doi.org/10.1006/rwgn.2001.1599.

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Morse, H. C. "Mouse Leukemia Viruses." In Brenner's Encyclopedia of Genetics. Elsevier, 2001. http://dx.doi.org/10.1016/b978-0-12-374984-0.00978-5.

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Hinrichs, Steven H., Lian-sheng Chen, Joseph Fontes, and Gilbert Jay. "Human T-cell Leukemia Virus Type I (HTLV-I): Studies of Disease Mechanism in a Transgenic Mouse System." In The Human Retroviruses. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-08-091832-7.50016-9.

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Conference papers on the topic "Mouse leukemia viruses"

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Zhang, Yu-An, Jer-Tsong Hsieh, Anirban Maitra, et al. "Abstract 4292: Frequent detection of xenotropic murine leukemia virus (XMLV) strains including XMRV in human cultures established from mouse xenografts." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-4292.

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