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Dissertations / Theses on the topic 'Mouse'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Lunde, Robert C. (Robert Charles). "The Country Mouse and the City Mouse." Thesis, North Texas State University, 1987. https://digital.library.unt.edu/ark:/67531/metadc501094/.

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The purpose of this play is to dramatize the fable of a city mouse and her cousin in the country, and the differences in their lifestyles. Through visits to each other's respective homes, the mice discover that there is more to life than what their own environment has to offer.

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2

Murray, Patricia Ann. "Early mouse development." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366681.

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The five manuscripts presented here concern events that occur during the early stages of mouse development, beginning with differentiation of primitive endoderm and ending with formation of the proamniotic cavity. The main focus of the work has been the role of the basement membrane in early development, with particular reference to its role in the regulation of epiblast and extraembryonic endodermal cell differentiation, parietal endodermal cell migration and programmed cell death (manuscripts 1, 3 and 4). HOW"9ver,the critical role played by the basement membrane in these processes prompted

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3

Diament, Adam Louis. "A genetic dissection of mouse obesity genes with congenic mouse models /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2004. http://uclibs.org/PID/11984.

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4

Van, Zant Jeffrey L. Wooten Michael Conrad. "Molecular ecology of Peromyscus polionotus." Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Spring/doctoral/VAN_ZANT_50.pdf.

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5

Bielohuby, Maximilian. "The mouse adrenal gland." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-76065.

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6

Beierbach, Elaine. "Lobulation in mouse cerebellum." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ64940.pdf.

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7

Arnold, Tessa Jean. "The Mouse Magnetic Compass." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/53833.

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All five classes of vertebrates use the geomagnetic field for spatial orientation. The geomagnetic field can be used to derive both 'map' and 'compass' information. There is evidence for two different mechanisms used to sense the magnetic field, the radical pair mechanism (RPM) and the magnetite based mechanism (MBM). C57BL/6 laboratory mice can rely on directional information from the magnetic field to position their nests and to solve a water maze task. The primary objective of this research was to characterize the magnetic compass of C57BL/6 laboratory mice in the plus water maze ta

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8

Rastogi, Ravi. "POSITION CONCORDANT - HAPTIC MOUSE." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1699.

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Haptic mice, computer mice modified to have a tactile display, have been developed to enable access to computer graphics by individuals who are blind or visually impaired. Although these haptic mice are potentially very helpful and have been frequently used by the research community, there are some fundamental problems with the mouse, limiting its acceptance. In this paper we have identified the problems and have suggested solutions using one haptic mouse, the VT Player. We found that our modified VT Player showed significant improvement both in terms of the odds of obtaining a correct respon

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9

Bertenyi, Katalin K. A. "The use of transgenic mouse Muta Mouse to study 1,8-dinitropyrene-induced mutagenesis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0031/MQ27042.pdf.

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10

Clemente, Emily. "Investigation of gene expression patterns in normal juvenile mouse testis and infertile mouse models." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597769.

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This thesis details the use of a series of cDNA libraries corresponding to several testis cell-types derived from juvenile mouse testes to investigate (i) the first wave of spermatogenesis in the wild-type mouse and four germ cell depleted mouse models where mutations have abrogated spermatogenesis at different points in the pathway (ii) mouse mutants with progressive deletions on the Y chromosome that perturb spermiogenesis (the final maturation stages of spermatogenesis). The gene expression patterns generated were validated by extensive comparison to existing data in the literature and the

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11

Alsén, Per. "Immunohistochemical evaluation of antibodies for staining of mouse spinal cord and mouse neuronal cells." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-204738.

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12

Bertenyi, Katalin K. A. (Katalin Kinga Alexandra) Carleton University Dissertation Biology. "The Use of the transgenic mouse MutaTM mouse to study 1,8- dinitropyrene-induced mutagenesis." Ottawa, 1997.

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13

Huo, Yongliang. "Mouse model of Cooley's anemia." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2009. https://www.mhsl.uab.edu/dt/2010r/huo.pdf.

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14

Yamada, Hiroyuki. "Molecular Clocks in Mouse Skin." 京都大学 (Kyoto University), 2010. http://hdl.handle.net/2433/120505.

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15

Widen, Cecilia, and n/a. "Energetics of Mouse Papillary Muscle." Griffith University. School of Physiotherapy and Exercise Science, 2006. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070228.121312.

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The overall aim of this Thesis was to characterise the energetic properties of the mouse papillary muscle as this preparation could become a useful model to study alterations of energetic aspects of cardiac pathologies and heart-focussed genetic changes. Measurements of resting and active metabolism of the papillary muscles were made in vitro using the myothermic technique. In the first study the mechanism underlying impaired contractility of post-ischaemic rat papillary muscle was investigated. The rat preparation is well established and was used to develop protocols and approaches that could

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16

Deconinck, Anne E. "Mouse models of neuromuscular disease." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320277.

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17

Barber, K. A. "Immunomodulation in the NOD mouse." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596341.

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A CD8<SUP>+</SUP> T cell clone was generated by priming non-diabetic NOD mice with C2, a K<SUP>d</SUP>-binding, 10-mer peptide (WYIPQSLRGV) derived from the large isoform of GAD. This clone (αC2.4) lyses NOD fibroblast targets transfected with a construct encoding human GAD<SUB>67</SUB>. This molecule is entirely homologous with mouse and rate GAD<SUB>67</SUB> at the C2 region and as such this observation indicates that C2 is a naturally processed epitope. The object of this project was to investigate the role of the C2 epitope and altered peptide ligand (APL) derivatives in IDDM pathogenesis

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18

Legge, M. "Determinants in preimplantation mouse development." Thesis, University of Essex, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235442.

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19

Stechman, Michael James. "Genetic mouse models of nephrolithiasis." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1116/.

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Nephrolithiasis is a common disorder of multifactorial aetiology. Although most patients have a family history, the underlying genetic causes are largely unknown. To identify novel genes for nephrolithiasis, large-scale radiological and biochemical screens of male mice derived from an N-ethyl-N-nitrosourea-mutagenesis (ENU) programme were performed. This identified models for genetic renal calcification (Rcalc1) and genetic hypercalciuria (Hcalc1). Rcalc1, an ENU-induced mutant with renal opacities on X-ray and histological renal papillary calcification, exhibited autosomal dominant transmissi

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20

Hong, Karen H. (Karen Hsiao-Ying) 1971. "Mouse modifiers of intestinal tumorigenesis." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/8585.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 2001.<br>Includes bibliographical references.<br>Colorectal cancer involves a series of molecular alterations as a normal cell progresses to malignancy. A large body of evidence points to the mutation of the APC gene as the pivotal event initiating intestinal tumorigenesis. Apdmin, an induced mutation in mouse homologue of APC, was identified several years ago by Moser et al., providing a genetic model system to study this process. We used the Apdmin system to identify additional genes influencing tumorigenesis. One of th

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21

Tam, Mandy Chi-Mun. "Genomic analysis of mouse tumorigenesis." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/37454.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2006.<br>Includes bibliographical references.<br>The availability of the human and mouse genome sequences has spurred a growing interest in analyzing mouse models of human cancer using genomic techniques. Comparative genomic studies on mouse and human tumors can be valuable in two major ways: in validating mouse models and in identifying genes that are common to mouse and human tumorigenesis. Many analytic tools have emerged in recent years for human genome mining. Some of these tools have been translated to the murine v

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22

Kelly, Robert George. "Hypervariable minisatellites in mouse DNA." Thesis, University of Leicester, 1990. http://hdl.handle.net/2381/34433.

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Hypervariable minisatellite loci provide highly informative genetic markers in mammalian genomes. Hybridisation probes based on a G-rich core sequence simultaneously detect many minisatellite loci in human DNA, generating individual specific and highly variable DNA fingerprints with a wide range of applications. Human minisatellite probes cross-hybridise to mouse DNA, generating DNA fingerprints as complex and variable as those of man. Inbred strains of mice have strain-specific DNA fingerprints which can be analysed using recombinant inbred strains. Analysis of the BXD recombinant inbred seri

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23

Wiltschko, Alexander Bame. "The Structure of Mouse Behavior." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493569.

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Complex animal behaviors are likely built from simpler modules, but their systematic identification in mammals remains a significant challenge. Here we use depth imaging to show that three-dimensional (3D) mouse pose dynamics are structured at the sub-second timescale by using a newly developed 3D imaging and machine learning-based automated phenotyping system, which we term Motion Sequencing (MoSeq). Computational modeling of these fast postural dynamics effectively describes mouse behavior as a series of reused and stereotyped modules with defined transition probabilities, which collectively

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24

Watiti, Tom Wanjala. "Vision-based virtual mouse system." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2009. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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25

Widen, Cecilia. "Energetics of Mouse Papillary Muscle." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/367649.

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The overall aim of this Thesis was to characterise the energetic properties of the mouse papillary muscle as this preparation could become a useful model to study alterations of energetic aspects of cardiac pathologies and heart-focussed genetic changes. Measurements of resting and active metabolism of the papillary muscles were made in vitro using the myothermic technique. In the first study the mechanism underlying impaired contractility of post-ischaemic rat papillary muscle was investigated. The rat preparation is well established and was used to develop protocols and approaches that could

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26

au, efilipov@murdoch edu, and Emilija Filipovska-Naumovska. "Development of methods for detection and eradication of mouse parvovirus from a laboratory mouse colony." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070918.145210.

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The mouse parvovirus designated MPV can infect laboratory mice and affect the humoral and cellular immune response of infected mice, reducing their value for biomedical and medical research. The development and maintenance of MPV-free mouse colonies for biomedical research is therefore essential and requires routine monitoring of the infection status of mice, using serological surveillance procedures. Recent experience in the Animal Resources Centre (ARC), a major supplier of mice to the medical research community in Australia, was that MPV infection was present but was not detectable with th

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27

Helstrom, Brian S. "Mouse methods of rotation in a two-dimensional space, comparisons using a two-ball mouse." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/mq35893.pdf.

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28

陳醒覺 and Sing-kwok Chan. "Mouse preproendothelin-1 gene: transgenic mouse models to study tissue-specific and developmental expression andregulation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B31236571.

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29

Filipovska-Naumovska, Emilija. "Development of methods for detection and eradication of mouse parvovirus from a laboratory mouse colony." Thesis, Filipovska-Naumovska, Emilija (2007) Development of methods for detection and eradication of mouse parvovirus from a laboratory mouse colony. PhD thesis, Murdoch University, 2007. https://researchrepository.murdoch.edu.au/id/eprint/676/.

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The mouse parvovirus designated MPV can infect laboratory mice and affect the humoral and cellular immune response of infected mice, reducing their value for biomedical and medical research. The development and maintenance of MPV-free mouse colonies for biomedical research is therefore essential and requires routine monitoring of the infection status of mice, using serological surveillance procedures. Recent experience in the Animal Resources Centre (ARC), a major supplier of mice to the medical research community in Australia, was that MPV infection was present but was not detectable with

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30

Filipovska-Naumovska, Emilija. "Development of methods for detection and eradication of mouse parvovirus from a laboratory mouse colony." Filipovska-Naumovska, Emilija (2007) Development of methods for detection and eradication of mouse parvovirus from a laboratory mouse colony. PhD thesis, Murdoch University, 2007. http://researchrepository.murdoch.edu.au/676/.

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The mouse parvovirus designated MPV can infect laboratory mice and affect the humoral and cellular immune response of infected mice, reducing their value for biomedical and medical research. The development and maintenance of MPV-free mouse colonies for biomedical research is therefore essential and requires routine monitoring of the infection status of mice, using serological surveillance procedures. Recent experience in the Animal Resources Centre (ARC), a major supplier of mice to the medical research community in Australia, was that MPV infection was present but was not detectable with

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31

Kim, Na-Hyun. "Introducing Deache mouse : An alternative computer mouse design for people with fine motor skill impairments." Thesis, Umeå universitet, Institutionen för informatik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-160907.

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32

Ruotsalainen, H. (Heli). "Lysyl hydroxylases:characterization of mouse lysyl hydroxylases and generation of genetically modified lysyl hydroxylase 3 mouse lines." Doctoral thesis, University of Oulu, 2005. http://urn.fi/urn:isbn:9514277392.

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Abstract Lysyl hydroxylase (EC 1.14.11.4, procollagen-lysine, 2-oxyglutarate, 5-dioxygenase, Plod) catalyzes the hydroxylation of certain lysine residues in collagens and in other proteins with collagenous domains. Three lysyl hydroxylase isoforms have been cloned from human and rat. The importance of lysyl hydroxylase 1 in collagen biosynthesis is demonstrated by the heritable disorder, Ehlers-Danlos syndrome type VI, which is characterized by joint laxity, progressive scoliosis, muscle hypotonia, scleral fragility and rupture of the ocular globe. An alternatively spliced form of lysyl hydrox

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33

Al-Janabi, Tamara. "Making a mouse model for schizophrenia : using the mouse to model the schizophrenia susceptibility gene ZNF804A." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/42404/.

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Schizophrenia is a complex disorder, with several genes putatively associated with the pathogenesis of the disorder. A large genome-wide association study (O’Donovan et al. 2008) identified ZNF804A as a candidate gene for schizophrenia (meta-analysis p = 1.61 x 10-7). The association of the gene with schizophrenia (and bipolar disorder) has since been successfully replicated several times, confirming the association (Riley et al., 2010; Steinberg et al., 2010; Zhang et al., 2010, Williams et al., 2011). The aim of this thesis is to create and provide preliminary assessments of a mouse model of

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34

Chan, Sing-kwok. "Mouse preproendothelin-1 gene : transgenic mouse models to study tissue-specific and developmental expression and regulation /." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19737002.

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35

Dolan, Jennifer M. "Thyroid Histology and Reproductive Function in the Prairie Deer Mouse and in the White-Footed Mouse." W&M ScholarWorks, 1990. https://scholarworks.wm.edu/etd/1539625585.

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36

Gormally, Emmanuelle. "An investigation of the mouse mutant tattered." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267899.

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37

Yu, Tian. "Role of Gli3 in the developing mouse forebrain." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/4382.

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The mammalian forebrain, which consists of the telencephalon and the diencephalon, is responsible for many higher cognitive functions such as thinking, learning and memory. The cerebral cortex, which is important for language and processing information, is located in the dorsal portion of the telencephalon. The basal ganglia, which are important for movement, are located in the ventral telencephalon. Many genes are involved in patterning and the development of the forebrain. One gene that appears to be crucial for forebrain development is Gli3. Gli3 has been shown to work as both a transcripti

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38

鈴木, 伸之介. "マウス卵母細胞および初期胚におけるエピジェネティック修飾と発生能に関する研究". Kyoto University, 2015. http://hdl.handle.net/2433/199532.

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39

Suzuki, Shinnosuke. "Studies on the developmental potential and epigenetic modifications of mouse oocytes and preimplantation embryos." Kyoto University, 2015. http://hdl.handle.net/2433/199350.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第19026号<br>農博第2104号<br>新制||農||1030(附属図書館)<br>学位論文||H27||N4908(農学部図書室)<br>31977<br>京都大学大学院農学研究科応用生物科学専攻<br>(主査)教授今井裕, 教授久米新一, 教授松井徹<br>学位規則第4条第1項該当

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40

JONES, EVAN FIELDING. "DEVELOPMENT OF THE LASER REMOTE MOUSE." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1085766388.

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41

Böhm, Bernd R. "Quantitative modelling of mouse limb morphogenesis." Doctoral thesis, Universitat Pompeu Fabra, 2011. http://hdl.handle.net/10803/31967.

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In this thesis we combine quantitative measurements of mouse limb morphogenesis and computer modelling to test a well established theory about the cellular mechanisms promoting limb elongation. A distally directed gradient of cellular proliferation was believed to be the driving mechanism for limb outgrowth. We find that the empirically measured spatial proliferation pattern fails to promote normal development - a reverse engineering algorithm was applied and revealed a proliferation pattern that could indeed carry out normal development. The differences between those patterns is dramatic and

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42

Hajkova, Petra. "Epigenetic reprogramming in mouse germ cells." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=970526938.

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43

Carlson, Anne Elizabeth. "Signaling mechanisms of mouse sperm capacitation /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/10539.

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44

Chapouton, Prisca. "Regionalization of the developing mouse telencephalon." Diss., lmu, 2002. http://nbn-resolving.de/urn:nbn:de:bvb:19-11597.

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45

Lindsay, Elizabeth Anne. "Photodynamic therapy of a mouse glioma." Thesis, Imperial College London, 1991. http://hdl.handle.net/10044/1/46889.

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46

Palidwor, Gareth A. "Tissue-specific codon usage in mouse." Thesis, University of Ottawa (Canada), 2011. http://hdl.handle.net/10393/28932.

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Codon usage bias is due to a combination of biased mutation and selection effects. Isochore-related GC mutational bias has been shown to be the dominant cause of tissue-specific codon bias in adult human tissues and limited evidence for translational selection has been shown. This thesis is a comprehensive evaluation of the relative contribution of selection and mutation to variation in codon usage among different mouse embryonic tissues. Through a detailed analysis of tissue-specific codon usage in relation to gene expression and gene location of mouse embryonic tissue-specific genes, I found

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47

Elfving, Anna. "Transcriptional regulation of mouse ribonucleotide reductase." Licentiate thesis, Umeå universitet, Institutionen för medicinsk kemi och biofysik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-41272.

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All living organisms are made of cells and they store their hereditary information in the form of double stranded DNA. In all organisms DNA replication and repair is essential for cell division and cell survival. These processes require deoxyribonucleotides (dNTPs), the building blocks of DNA. Ribonucleotide reductase (RNR) is catalyzing the rate limiting step in the de novo synthesis of dNTPs. Active RNR is a heterodimeric protein complex. In S phase cells, the mouse RNR consists of the R1 and the R2 proteins. The R1/R2 RNR-complex supplies the cell with dNTPs required for DNA replication. Ou

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48

Tyas, David Anthony. "Generation of a Pax6 reporter mouse." Thesis, University of Edinburgh, 2004. http://hdl.handle.net/1842/27562.

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In order to better understand Pax6 function I generated a novel tool – a ‘<i>Pax6</i> reporter’ transgenic mouse that expresses GFP under the control of <i>Pax6</i> regulatory elements. The transgenic mouse was generated from a modified yeast artificial chromosome (YAC) that contains the human <i>PAX6</i> gene and has been previously demonstrated to rescue loss of endogenous <i>Pax6</i> in <i>Pax6<sup>sey/sey</sup></i><sub> </sub>mice. The key advantages of a YAC addition transgenic include that it is already known that <i>Pax6</i> regulatory elements are present over a 200Kb region and insert

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49

Petersson, Johan. "Notch signaling pathways inthe obese mouse." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-66818.

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50

Qin, Yinghao. "The Smart Phone as a Mouse." The University of Waikato, 2006. http://hdl.handle.net/10289/2289.

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With the development of hardware, mobile phone has become a feature-rich handheld device. Built-in camera and Bluetooth technology are supported in most current mobile phones. A real-time image processing experiment was conducted with a SonyEricsson P910i smartphone and a desktop computer. This thesis describes the design and implementation of a system which uses a mobile phone as a PC mouse. The movement of the mobile phone can be detected by analyzing the images captured by the onboard camera and the mouse cursor in the PC can be controlled by the movement of the phone.

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