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Journal articles on the topic 'Mouth Dissolving Film'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Pawar, Rajat, Ravi Sharma, Pravin Sharma, and G. N. Darwhekar. "A Review on Mouth Dissolving Film." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 206–10. http://dx.doi.org/10.22270/jddt.v9i6.3676.

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Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance characteristics as p

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2

Jain, Priyanshi, Ashish Gupta, and Gajanan Darwhekar. "An Detailed Overview on Mouth Dissolving Film." Journal of Drug Delivery and Therapeutics 13, no. 7 (2023): 172–76. http://dx.doi.org/10.22270/jddt.v13i7.6121.

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The present review aims to enlighten about a potential dosage form that is mouth dissolving films. Mouth dissolving film is a rapidly dissolving dosage form that dissolves in the mouth within a few seconds without the intake of water and is mainly used for pediatric and geriatric patients due to its flexibility and patient compliance. It is a potential dosage form for drugs having high metabolism and low bioavailability. Solvent casting, hot melt extrusion, solid dispersion, semisolid casting, rolling, and other processes can all be used to create mouth dissolving film, but solvent casting is

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3

Ankit, Lodhi* Kavita Lovanshi Rita Mourya. "A Review on Mouth Dissolving Film." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3154–56. https://doi.org/10.5281/zenodo.15295920.

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Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. This review gives an idea about formulation techniques, evaluation parameters, overview on packagin

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4

Daharwal, Shrinoy, Rajat Pawar, and Sunita Sonartiya. "A REVIEW ON MOUTH DISSOLVING FILM." International Journal of Pharmaceutical Sciences and Medicine 7, no. 5 (2022): 48–59. http://dx.doi.org/10.47760/ijpsm.2022.v07i05.005.

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Oral route of Mouth dissolving film is the most advanced oral solid dosage form due which it is very much in use now a day because of it’s flexibility and comfort. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within few minutes when placed in tongue without taking water. This dosage form allows the medication to bypass the first pass metabolism, so that the bioavailability of medication can be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films inv

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AR, Nannar. "Novel Advancements in Mouth Dissolving Film Technology." Pharmaceutical Drug Regulatory Affairs Journal 7, no. 1 (2024): 1–14. http://dx.doi.org/10.23880/pdraj-16000156.

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Mouth dissolving film (MDF) technology has emerged as an innovative drug delivery platform offering rapid drug absorption and enhanced patient compliance. This comprehensive review explores recent advancements in MDF technology, focusing on formulation strategies, manufacturing techniques, and applications in pharmaceutical and nutraceuticals industries.

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6

Swati, Saxena, Patel Abhishek, and Kumar Jain Sarang. "Formulation and evaluation of mouth dissolving film of antihypertensive agentFormulation and evaluation of mouth dissolving film of antihypertensive agent." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 1107–16. https://doi.org/10.5281/zenodo.7790668.

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Mouth dissolving film is the one of the most advanced oral solid dosage form because of its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance chara

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7

Swati Saxena, Abhishek Patel, and Sarang Kumar Jain. "Formulation and evaluation of mouth dissolving film of antihypertensive agentFormulation and evaluation of mouth dissolving film of antihypertensive agent." World Journal of Advanced Research and Reviews 16, no. 2 (2022): 1107–16. http://dx.doi.org/10.30574/wjarr.2022.16.2.1251.

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Mouth dissolving film is the one of the most advanced oral solid dosage form because of its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage form allows the medication to bypass the first pass metabolism so bioavailability of medication may be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance chara

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8

Bhalse, Pinki, Apurva Pagare, and Rajat Pawar. "A REVIEW ON MOUTH DISSOLVING FILM." International Journal of Pharmaceutical Sciences and Medicine 9, no. 1 (2024): 82–93. http://dx.doi.org/10.47760/ijpsm.2024.v09i01.007.

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Oral route is considered as one of the most convenient route for administration of various pharmaceutical dosage forms like, tablet, capsule, syrup, suspension and emulsion. Fast Dissolving Drug Delivery systems have developed various fast disintegrating preparations like mouth dissolving film, MDT. Oral thin film are new dosage form that are prepared from hydrophilic polymer which are when placed in mouth, buccal cavity disintegrate rapidly. Mouth dissolving film is superior as compare to mouth dissolving tablet as the cost of production is low. Geriatric and pediatric patients are facing dif

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9

Bhavana, Patil*1 Sandip Tadavi2 S. Patil3 Sunil Pawar4. "A Review on Mouth Dissolving Film." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1623–33. https://doi.org/10.5281/zenodo.15044503.

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A new medication administration method called "fast dissolving oral film" uses hydrophilic polymers to create an ultra-thin film that dissolves quickly on the tongue's or the buccal cavity's floor or top. It is a postage stamp-sized, ultrathin strip (50–150 microns thick) that contains an active ingredient and additional excipients and was created using transdermal patch technology. The film dissolves on the tongue in a matter of seconds after application, preventing first-pass metabolism and perhaps boosting the drug's bioavailability. Greater surface area accessibility causes fast sali

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Nagendra, R.1 Sheetal P.*2 Nanditha V. V.3 Venkatesh K.4 Hanumanthachar Joshi5. "Oral Disintegrating Film: A Review." International Journal in Pharmaceutical Sciences 2, no. 2 (2024): 206–16. https://doi.org/10.5281/zenodo.10640441.

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Oral disintegrating films (ODF) hold great promise for novel and inventive drug delivery methods. Because it is flexible and comfortable to use, mouth dissolving film is the most advanced oral solid dosage form available. Mouth dissolving films are oral solid dosage forms that, when placed in the mouth without water or chewing, dissolve and disintegrate within a minute. With this dosage form, the drug can avoid the first pass metabolism, potentially increasing its bioavailability. Mouth dissolving films have the ability to reduce dosage, improve the onset of action, and get rid of choking anxi

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11

Patil, Pallavi C., S. K. Shrivastava, Vaidehi S., and Ashwini P. "ORAL FAST DISSOLVING DRUG DELIVERY SYSTEM: A MODERN APPROACH FOR PATIENT COMPLIANCE." International Journal of Drug Regulatory Affairs 2, no. 2 (2018): 49–60. http://dx.doi.org/10.22270/ijdra.v2i2.131.

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This review represents importance of mouth dissolving films as compared to other oral dosage forms. Fast dissolving oral drug delivery system are solid dosage form which disintegrate or dissolve within seconds when placed in the mouth without need of water or chewing. First developed fast dissolving dosage form in formulation and the rapid disintegrating properties were obtained through a special procedure or formulation modification, hence mouth dissolving film is proved to be better alternative in such cases. This fast dissolving drug delivery system is suited for the drugs which undergo hig

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12

Manish, Kumar Gupta, Priya Sakshi, Singh Sudharshana, and Verma Sunil. "FORMULATION AND EVALUATIONS OF MOUTH DISSOLVING FILM USING NATURAL EXCIPIENTS." International Journal of Current Pharmaceutical Review and Research 13 (December 30, 2021): 28–37. https://doi.org/10.5281/zenodo.12667156.

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Mouth dissolving film (MDFs) is the latest oral solid dosage form because of its easy-to-useproperties. When mouth dissolving films are placed in mouth, it disintegrates and dissolveswithin a minute without consuming water or chewing. This dosage form has added advantageas it allows the medication to bypass the first pass metabolism, so bioavailability ofmedication may be enhanced. Mouth dissolving film has capability to enhance onset ofaction, lower the dosing and eliminate the fear of chocking. Over the past years, MDFs haveappeared as effective oral care products as dosage forms for deliver

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13

Mastiholimath, Vinayak Shivamurthi, Sujit Prabhu Khope, Pallavi Raosaheb Chiprikar, Anand Shripal Ammanage, and Umeshkumar Dinesh Patel. "Nano-suspension loaded mucoadhesive mouth dissolving film of meclizine hydrochloride." Journal of Medical pharmaceutical and allied sciences 12, no. 3 (2023): 5874–84. http://dx.doi.org/10.55522/jmpas.v12i3.5037.

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Meclizine Hydrochloride belongs to class H1 antagonist, antiemetic and anti-vertigo in nature, it is a Biopharmaceutical classification system (BCS) class II drug and is practically insoluble in water. The bottom-up approach was used in the formulation of nanosuspension in which methanol and millipore water was used as solvent and anti-solvent respectively, the stabilizers used for preparation were Polyvinylpyrrolidone K30 (PVP K30) and Hydroxypropyl Methylcellulose E15 (HPMC E15) which were found to be compatible with the formulation after Fourier Transform Infrared (FTIR) and Differential sc

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14

Ruchi, Kashyap* Neha Sodiyal Dr. Shivanand Patil. "Preparation And Evaluation of Mouth Dissolving Film of Fexofinadine Hydrochloride." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 3012–21. https://doi.org/10.5281/zenodo.14547851.

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Mouth dissolving films are at the forefront of oral solid dosage forms, offering enhanced comfort and versatility. They outperform fast-dissolving tablets by rapidly dissolving in the mouth with reduced saliva, hence enhancing the effectiveness of the active pharmaceutical ingredient (API). These films are a popular choice among consumers compared to traditional tablets or capsules because they do not require chewing or water for administration. The emerging technology of oral mouth dissolving films demonstrates significant potential due to its capacity to meet diverse requirements. The main g

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Sakshi, D. Patil* Shubhangi S. Ambekar Sandip A. Tadavi Sunil P. Pawar. "Review On Mouth Dissolving Film: The Advancement In Oral Drug Delivery." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 559–68. https://doi.org/10.5281/zenodo.10824195.

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Mouth dissolving films are the kind of drug delivery system which is gaining interest from a wide range of pharmaceutical industries. This is due to there  convenience and it’s easy to use than other dosage forms like buccal tablets and sublingual tablets. By studying transdermal patch technology, mouth dissolving film was formulated. Thin, solid dosage forms called mouth dissolving films dissolves in the mouth within seconds to a minute without chewing or water intake. Because of the oral buccal mucosa's high vascularization, medications can be absorbed immediately and reach the bl

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16

Mishra, Soumya, Nidhi Bais, and Sachin Kumar Jain. "Formulation and Evaluation of Mouth Dissolving Film of Imipramine HCL." Journal of Biomedical and Pharmaceutical Research 12, no. 4 (2023): 22–29. http://dx.doi.org/10.32553/jbpr.v12i4.1015.

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The main objective of the present study outlines a systematic approach for Design and Evaluation of Fast Dissolving Oral Films of Imipramine HCl to enhance the therapeutic efficacy and provide rapid onset of action in patients suffering from depression Because of patient may have trouble in swallowing a tablet or capsules. Mouth dissolving film is the most advanced oral solid dosage form due to its flexibility and comfort in use. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within a minute when placed in mouth without taking water or chewing. This dosage for

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17

Adhikari, Diwas, Sharada Pokhrel, Meenakshi Kandwal, and Shivanand Patil. "Effect of Variation of Concentration of Film Forming Polymer and Superdisintegrating Agent on Release Profile of Mouth Dissolving Film of Telmisartan." Journal of Drug Discovery and Health Sciences 2, no. 01 (2025): 1–6. https://doi.org/10.21590/jddhs.02.01.01.

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Mouth dissolving films offer the extensive range of benefits and among them patient compliance and easiness for taking the drug without water are the superior one. For the formation of the mouth dissolving films different material can be used such as film forming polymer, superdisintegrants, saliva stimulating agents, surfactants or wetting agents, buffering agents, plasticizers etc. Combination of these agents at suitable concentration helps in the formation of mouth dissolving film of required quality. Role of the superdisintegrants is considered crucial. Higher concentration of superdisinte

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18

Solanki, Dharmendra. "Formulation and evaluation of fast dissolving film of haloperidol." Journal of Pharmaceutical and Biological Sciences 12, no. 1 (2024): 53–59. http://dx.doi.org/10.18231/j.jpbs.2024.009.

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The present research work was designated towards formulation development of fast dispersible films of Haloperidol that possesses acceptable taste, mechanical strength and rapid disintegration to provide desired drug release property and pleasant mouth feel, for improving patient compliance, especially in pediatric and geriatric population. The aim of the study is to formulate Mouth dissolving film of Haloperidol an antipsychotic drug to improve the efficacy and patient compliance. In the present work, an attempt is made to develop Mouth dissolving film of Haloperidol with the use of hydroxymet

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19

Wadher, Kamlesh J., Charvi J. Kubde, Swati D. Malkote, Manasi S. Thakre, Chetna J. Shelote, and Milind J. Umekar. "Formulation and Characterization of Montelukast Sodium Mouth Dissolving Film Using Cress Seed Mucilage." Journal of Drug Delivery and Therapeutics 13, no. 2 (2023): 16–20. http://dx.doi.org/10.22270/jddt.v13i2.5891.

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There is a rising interest in the development of orodispersible films (ODFs) as an alternative to fast dissolving tablets which is attributed to their faster dissolution rate, higher durability, and better patient compliance. Owing to its rheological and also various functional properties, many researchers tried to discover some of the pharmaceutical applications of L. sativum in the development of various dosage forms, in addition to its therapeutic studies, such as binding, dissolving, gelling and sustained release dosage form. The fast-dissolving oral film of the Montelukast sodium by using

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20

Darekar, A. B., S. M. Sonawane, and R. B. Saudagar. "Formulation and Evaluation of Orally Fast Dissolving Wafer by Using Natural Gum: Review Article." International Journal of Current Pharmaceutical Review and Research 9, no. 3 (2017): 253–60. https://doi.org/10.5281/zenodo.12674551.

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Oral thin film a new drug delivery system for the oral delivery of the drugs, was developed based on the technology of thetransdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min whenplaced in the mouth without drinking water or chewing. Oral film includes various ingredients for its formulation. Fastdissolving film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering thedrugto the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used

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Darekar, A. B., S. M. Sonawane, and R. B. Saudagar. "Formulation and Evaluation of Orally Fast Dissolving Wafer by Using Natural Gum: Review Article." International Journal of Current Pharmaceutical Review and Research 8, no. 3 (2024): 253–60. https://doi.org/10.5281/zenodo.12677573.

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Oral thin film a new drug delivery system for the oral delivery of the drugs, was developed based on the technology of thetransdermal patch. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min whenplaced in the mouth without drinking water or chewing. Oral film includes various ingredients for its formulation. Fastdissolving film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering thedrugto the systemic circulation via dissolution when contact with liquid is made. Water-soluble polymers are used

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22

Avinash, Bichave* Somesh Phate Vaishnavi Naik Anushka Gaikwad Lalit Choudhary Uttam Choudhary Shrutika Patil. "Evaluation Parameters For Mouth Dissolving Films." International Journal of Pharmaceutical Sciences 2, no. 7 (2024): 197–208. https://doi.org/10.5281/zenodo.12623624.

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Mouth dissolving films (MDFs) represent a significant advancement in drug delivery systems, providing an alternative to conventional tablets and capsules. This review explores the evaluation parameters critical to ensuring the quality, efficacy, and safety of MDFs. These parameters include disintegration time, weight variation, film thickness and uniformity, tensile strength, surface pH, drug content uniformity, and in vitro drug release. The emphasis is on understanding these parameters' roles and the advanced techniques used in their assessment. Regulatory considerations and challenges in fo

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Vrushali, S. Gangurde*1 Pradnya H. Kapse2 Khanderao Jadhav3 Rishikesh Bachhav4. "Mouth Dissolving Films: A novel approach in oral drug delivery." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 1223–36. https://doi.org/10.5281/zenodo.11080675.

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The most sophisticated oral solid dose forms are mouth dissolving or orodispersible films because of their versatility and ease of usage. The Mouth Dissolving film is a solid oral dosage form that, when placed in the mouth without water or chewing, dissolves and decomposes rapidly. By avoiding first pass metabolism, the drug's bioavailability is increased when taken in this dosage form. Additionally, orodispersible films may result in a lower dosage, a quicker onset of action, and no choking hazards. Solvent casting and semisolid casting methods are used to laminate API chemicals that mask fla

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Praveena, Pepakayala, and K. Anne Vijetha. "A Review Article on Self - Micro Emulsifying Mouth Dissolving Film." International Journal of Science and Research (IJSR) 10, no. 9 (2021): 926–30. https://doi.org/10.21275/mr21916110005.

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Ghule, Minal. "Formulation and Characterization of Lanthanum Carbonate Oral Mouth Dissolving Film." International Journal of Science and Research (IJSR) 10, no. 12 (2021): 895–97. https://doi.org/10.21275/sr21924165822.

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26

Rahul, Rohidas Maske, Rajaram Mahajan Vijay, and Bhagwan Bhalerao Sakshi. "Polymers used in mouth dissolving film: A review." World Journal of Advanced Research and Reviews 16, no. 3 (2022): 378–89. https://doi.org/10.5281/zenodo.7895277.

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The oral route is one of the most important routes for local and systemic drug delivery, as it has a large surface, high permeability, and rich blood supply. Mouth dissolving films, are now becoming more popular than fast-dissolving tablets. The films are designed to disintegrate quickly when they come into touch with a surface that contains water, such the tongue. This allows the consumer to consume the product without the use of water. It can boost patient compliance and provide you a marketing advantage. The polymer used in mouth dissolving films is crucial to their quick dissolution and di

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Rahul Rohidas Maske, Vijay Rajaram Mahajan, and Sakshi Bhagwan Bhalerao. "Polymers used in mouth dissolving film: A review." World Journal of Advanced Research and Reviews 16, no. 3 (2022): 378–89. http://dx.doi.org/10.30574/wjarr.2022.16.3.1318.

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The oral route is one of the most important routes for local and systemic drug delivery, as it has a large surface, high permeability, and rich blood supply. Mouth dissolving films, are now becoming more popular than fast-dissolving tablets. The films are designed to disintegrate quickly when they come into touch with a surface that contains water, such the tongue. This allows the consumer to consume the product without the use of water. It can boost patient compliance and provide you a marketing advantage. The polymer used in mouth dissolving films is crucial to their quick dissolution and di

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Varsha, Ahirwar, Khushwant S. Yadav, and Shailendra Bindaiya. "Formulation Development and Evaluation of Fast Dissolving Films of Oloptadine HCl." Asian Journal of Research in Pharmaceutical Sciences 11, no. 2 (2021): 103–8. http://dx.doi.org/10.52711/2231-5659.2021-11-2-2.

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Our studies on the performance of formulation development and evaluation of fast dissolving films of Oloptadine HCL its anti-allergic drug. Prepare mouth dissolving film of Oloptadine HCl by solvent casting method. To characterize the prepared mouth dissolving film of Oloptadine HCL in terms of— Thickness, percent elongation, tack test, swelling index, in-vitro disintegration time and dissolution test. Oloptadine OLO), 11-[{z}-3-(Dimethlamino) propylidene]-6-11-dihydrobenz [b, e] oxepin-2-acetic acid hydrochloride, is widely used as an antihistaminic. Oloptadine HCL is a relatively selective h

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Shivani, Honmode* Prakash katakam Jadhav S. B. "Comprehensive Review on Fast Mouth Dissolving Film As Novel Drug Delivery System." International Journal in Pharmaceutical Sciences 2, no. 1 (2024): 124–41. https://doi.org/10.5281/zenodo.10477153.

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Fast mouth dissolving films are solid dosage types that, when placed in the mouth, dissolve or disintegrate over the course of a few seconds. They are not manufactured or palatable. Fast-dissolving films are becoming more popular as an alternative to quick-dissolving tablets in order to reduce patients' concerns about choking and to overcome patients' obstacles. A complex alternative to the traditional pills, capsules, and liquids often associated with prescription and over-the-counter drugs is the quickly disintegrating thin film. Thin film strips are often intended for oral administration, w

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Reddy, Shimmula R., and Bomma Ramesh. "In vivo Evaluation of Fluvoxamine Maleate Mouth Dissolving Films by Design of Experiment." International Journal of Pharmaceutical Sciences and Drug Research 13, no. 03 (2020): 326–33. http://dx.doi.org/10.25004/ijpsdr.2021.130313.

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Fluvoxamine, an antidepressant belonging to serotonin reuptake inhibitor (SRI) class, exhibits maximum absorption through the oral route of administration. The objective of current research is to formulate mouth dissolving fluvoxamine films by employing super disintegrants. The central composite design (CCD), employed to examine the effects of amount of hydroxypropyl methylcellulose (HPMC) E15 (A), amount of eudragit RL 100 (B), amount of polyethylene glycol (PEG 4000) (C) on response variables tensile strength, disintegration time and cumulative % drug released. A 27 formulations prepared acc

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Teja, D., E. Jasvanth, B. Mounika, and Buchi N. Nalluri. "Formulation and Evaluation of Chlorpheniramine Maleate Mouth Dissolving Films." Journal of Drug Delivery and Therapeutics 9, no. 1-s (2019): 244–51. http://dx.doi.org/10.22270/jddt.v9i1-s.2417.

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The present investigation was aimed at preparation and evaluation of mouth dissolving films (MDFs) of an anti-histamine drug, Chlorpheniramine Maleate (CPM) to enhance convenience and compliance to the elderly and paediatric patients. The MDFs were prepared using wet film applicator and evaluated for physicochemical and physicomechanical properties. MDFs were prepared with 0.6% and 0.8% w/w CPM. The MDFs with 0.8% w/w drug load showed re-crystallisation within 10 days, while the MDFs with 0.6% w/w CPM load were transparent with no re-crystallization. The effect of film formers, film thickness,

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Khunteta, Alok, Manish Kumar Gupta, and Surendra Kumar Swarnkar. "Formulation of Rapid Dissolving Films Containing Granisetron Hydrochloride and Ondansetron Hydrochloride." Journal of Drug Delivery and Therapeutics 9, no. 4-A (2019): 516–27. http://dx.doi.org/10.22270/jddt.v9i4-a.3525.

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The oral mucosa is conveniently and easily accessible and therefore allows uncomplicated application of dosage forms. A rapid-dissolving drug delivery system, in most cases, is a tablet that dissolves or disintegrates in the oral cavity without the need for water or chewing. More recently, fast-dissolving films are gaining interest as an alternative to fast-dissolving tablets to definitely eliminate patients’ fear of chocking and overcome patent impediments. In the present study, calculations for amount of drugs were determined, Rapid dissolving films containing GSH were prepared using solvent

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Singh, Prashant Kumar, Devender Singh, and Rohit Kumar Bijauliya. "Formulation and characterization of mouth dissolving mucoadhesive buccal film of Zolmitriptan." International Journal of Research and Development in Pharmacy & Life Sciences 6, no. 3 (2017): 2625–30. http://dx.doi.org/10.21276/ijrdpl.2278-0238.2017.6(3).2625-2630.

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Rao, Y. Srinivasa, and K. Adinarayana Reddy. "Design and In vivo Evaluation of Palonosetron HCl Mouth Dissolving Films in the Management of Chemotherapy-Induced Vomiting." International Journal of Pharmaceutical Sciences and Nanotechnology 10, no. 6 (2017): 3929–36. http://dx.doi.org/10.37285/ijpsn.2017.10.6.9.

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Fast dissolving oral delivery systems are solid dosage forms, which disintegrate or dissolve within 1 minute in the mouth without drinking water or chewing. Mouth dissolving film (MDF) is a better alternate to oral disintegrating tablets due to its novelty, ease of use and the consequent patient compliance. The purpose of this work was to develop mouth dissolving oral films of palonosetron HCl, an antiemetic drug especially used in the prevention and treatment of chemotherapy-induced nausea and vomiting. In the present work, the films were prepared by using solvent casting method with various

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Vinod, Bhendale* Trupti Kadam Rishikesh Bachhav. "Formulation Development and Evaluation of Mouth Dissolving Film of Ivabradine HCL." Int. J. in Pharm. Sci. 1, no. 8 (2023): 79–88. https://doi.org/10.5281/zenodo.8244885.

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Oral film is the latest technology in the production of oral disintegrating dosage forms. They are thin and elegant films of edible water-soluble polymers of various sizes and shapes (such as square, rectangular or disc). The stripes can be flexible or brittle, opaque or transparent. The present investigation was undertaken to formulate Ivabradine HCL oral films. For the treatment of hypertension. F1-F3 were carried out with HPMC E15 cps, PEG 400, sodium saccharin, citric acid and flavor. The films were clear and transparent. The thickness also uniform. The flexibility also good. The films sho

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Singh, Swati, Rajat Pawar, and Sunita Patidar. "A REVIEW ON MOUTH DISSOLVING FILM- A NOVEL APPROACH." International Journal of Pharmaceutical Sciences and Medicine 9, no. 2 (2024): 36–51. http://dx.doi.org/10.47760/ijpsm.2024.v09i02.006.

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The oral route is one of the most important routes for local and systemic drug delivery due to its large surface area, high permeability and blood flow. Mouth dissolving films are the most advanced oral forms as they are simpler and easier to use than other dosage forms such as Oro-soluble tablets, sublingual tablets. Fast dissolving drug delivery system were rapidly developed in the 1970s as an alternative to capsules, syrups, and tablets for adults and adolescents who have difficulty swallowing conventional oral solid dosage form. The Oro- soluble film dissolves and disintegrates in less tha

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Thakare, Mahesh M., and Sarita Karole. "Formulation, Statistical Optimization and Stability Study of Ondansetron Films." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 13, no. 04 (2022): 377–84. http://dx.doi.org/10.25258/ijpqa.13.4.06.

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Nausea and/or vomiting is common in patients of all ages. Nausea and vomiting can occur for a variety of reasons and may be related to illness or treatment. Careful study of the receptors involved has aided in the selection of drug classes to treat patients (34). This study aimed to prescribe an oral dissolving film of the antiemetic drug ondansetron for treating vomiting patients and nausea and vomiting (NVP) in pregnancy. The goal for optimizing the orally dissolving ondansetron film was to reduce disintegration time and maximize drug release from the film. The formulation of the mouth-disso

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Pattewar, Seema Venkatrao, Sanjay Bhaskar Kasture, Vishal Vivek Pande, and Swapnil K. Sharma. "A New Self Microemulsifying Mouth Dissolving Film." Indian Journal of Pharmaceutical Education and Research 50, no. 3s (2016): S191—S199. http://dx.doi.org/10.5530/ijper.50.3.29.

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Ayesha, patil* Sanika Bhosale Rutuja Gadade. "Oral Dispersed Film." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 377–82. https://doi.org/10.5281/zenodo.14051150.

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Oral dissolving films are advanced forms of oral medication designed to adhere to the buccal mucosa, offering both local and systemic effects. When compared to other oral drug delivery systems, these dosage forms are preferred due to their flexibility and comfort. These films make use of certain polymers with bio-adhesive properties, which, upon hydration, target a specific region of the body for a prolonged period, thus bypassing first-pass metabolism and enhancing bioavailability. This review aims to give an overview of fast-dissolving oral film. Recent advancements in technology have introd

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Patil, P. B., D. A. Patil, L. R. Zawar, B. Patil, and G. B. Patil. "DEVELOPMENT AND CHARACTERIZATION OF SUBLINGUAL FILM CONTAINING ROPINIROLE HYDROCHLORIDE." INDIAN DRUGS 56, no. 07 (2019): 33–42. http://dx.doi.org/10.53879/id.56.07.11513.

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In the present work films of ropinirole hydrochloride were prepared by using polymers such as hydroxy propyl methyl cellulose (HPMC E-15) and polyethylene glycol (PEG-400) as plasticizers, by a solvent casting method, for treatment of Parkinson's disease. HPMC E-15 was used as film forming agent in the range of concentration 50 mg – 600 mg and PEG-400 was used as plasticizer in the range of concentration 0.3-1.0 ml for solvent casting method. the optimized concentration of film forming agent was 400 mg and plasticizer concentration was 0.7ml. By using optimized concentration, Ropinirole Hydroc

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Ahmad Farooqui, Dr Nasiruddin, Ms Priyanka Ms. Priyanka, Mr Mohd Salman Mr. Mohd Salman, and Mr Praveen Kumar. "Formulation and evaluation of mouth dissolving film of polmacoxib." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 1739–49. https://doi.org/10.35629/4494-100317391749.

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The current work concentrates on the analytical quantification and formulation development of Polmacoxib, a selective COX-2 inhibitor, by establishing a UV spectrophotometric calibration curve and characterizing mouth-dissolving films (MDFs). Using UV spectrophotometry, a standard calibration curve of Polmacoxib was created. It showed great linearity in the concentration range of 2–12 µg/mL, with a strong link between absorbance and concentration, which proved that it could be used for quantitative analysis. After the analytical validation, several mouth-dissolving film formulations (F1–F6) of

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Avhad, Pawan S., Saurabh D. Nikam, Amit A. Chaudhari, Shital V. Wagh, Meghana S. Rayjade, and Prajwal Y. Gosavi. "Review on: Recent advances in mouth dissolving film." International Journal of Pharmaceutical Chemistry and Analysis 9, no. 4 (2023): 163–68. http://dx.doi.org/10.18231/j.ijpca.2022.030.

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The fast dissolving orally disintegrating film are the designed to dissolve upon contact with wet surface or fluids like saliva, within a few seconds. Like a tablet, capsule, oral liquids there is no need of additional liquids like water. This is the most convenient dosage form for patients and also provides marketing advantages. In pediatric, geriatric and patient who have fear of choking orally disintegrating film is most convenient and popular dosage form. As the drug I directly absorb in blood through mucus membrane in mouth the degradation of drug in GIT and the first pass metabolism of d

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Sk., Althaf B. Valli Manalan P. Prachet N. Rama Rao. "FORMULATION DEVELOPNENT AND EVALUATION OF NADOLOL ORAL FAST DISSOLVING FILMS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 09 (2019): 16098–107. https://doi.org/10.5281/zenodo.3406341.

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<em>The main goal in the development of any drug formulation is to achieve the complete drug release within the time or prior to it. Most of the drug delivery systems are successful because of their safety, most convenient and most economical drug delivery with highest patient compliance. In this a very thin oral strap consisting of drug disintegrates very fastly in the mouth and releases the drug into circulation the oral cavity therefore absorbed into the systemic.</em> <em>The aim of the present study is to formulate the oral fast dissolving films of Nadolol using HPMC K<sub>4</sub>M 

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Rao, Pingali Srinivasa, and T. Rama Mohan Reddy. "Formulation, Optimization and Evaluation of Rasagiline Mouth Dissolving Films." International Journal of Pharmaceutical Sciences and Nanotechnology 11, no. 6 (2018): 4323–31. http://dx.doi.org/10.37285/ijpsn.2018.11.6.5.

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The oral route is the most preferred route, though preoral administration of drug has disadvantage like hepatic first pass metabolism and enzymatic degradation within the GI tract. Trans-mucosal routes of drug delivery offer distinct advantage over preoral administration. The aim of present investigation was to formulate the fast-dissolving oral films (FDOF) of rasagiline, an anti-Parkinson drug. In the present study, rasagiline fast dissolving films were formulated by solvent-casting method containing HPMC 5cps, 15 cps and 50 cps as polymers and PEG 400 as plasticizer, Crospovidone and SSG as

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Attar, S. M., S. M. Ghurghure, and Sumit. "Teneligliptin hydrobromide hydrate mouth dissolving strip: Formulation and evaluation." International Journal of Pharmaceutical Chemistry and Analysis 11, no. 2 (2024): 164–70. http://dx.doi.org/10.18231/j.ijpca.2024.023.

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Oral route is considered as one of the most convenient route for administration of various pharmaceutical dosage form like tablet, capsule, syrup, suspension and emulsion. Fast Dissolving Drug Delivery systems have developed various fast disintegrating preparations like Oral disintegrating film, ODF. Oral disintegrating film is the solid oral drug delivery system, in which water soluble polymer involve to disintegrate film into mouth fastly. Oral disintegrating film is superior as compare to orally disintegrating tablet as the cost of production is low. The present research was undertaken to d

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Jaydeep, Mr Pawar, Mr Yalse Manoj, and Sonwane Sumit. "Turmeric-Based Mouth Dissolving Film for Ulcer Treatment." International Journal of Research in Pharmacy and Allied Science 04, no. 02 (2025): 115–18. https://doi.org/10.71431/ijrpas.2025.4211.

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This study explores the formulation and evaluation of a turmeric-based mouth dissolving film (MDF) designed for ulcer treatment. Turmeric, known for its active compound curcumin, possesses anti-inflammatory and antimicrobial properties that can aid in ulcer healing. The MDF provides a convenient and effective mode of drug delivery, ensuring rapid disintegration and absorption. The study involves formulation, characterization, and in vitro evaluation of the film, assessing parameters like tensile strength, disintegration time, and drug release profile. Results indicate enhanced curcumin bioavai

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Prajapati, Bhupendra G., Priyanka Patel, and Dhiren Patel. "Mouth dissolving film as a potential dosage form for paediatric usage." Journal of Pharmaceutical and Biological Sciences 11, no. 2 (2024): 133–41. http://dx.doi.org/10.18231/j.jpbs.2023.021.

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Drug delivery systems using thin films are being researched by the pharmaceutical industry. They're a diverse platform that can provide immediate, local, or systemic actions. Furthermore, these systems can be used independently, which is ideal for patients with dysphagia, elderly, pediatric, or bed-ridden patients, as well as those who may have difficulty consuming water. These drug delivery systems can be given by oral, buccal, sublingual, ocular and trans-dermal routes. This study explores mouth thin films in all of their characteristics from the current perspective, providing insight into t

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S., Nagajyothi* N. Maneesha V. Jyothi BukyaBhagawan V. N. Gayathri. "FORMULATION AND IN-VITRO EVALUATION OF ORAL FAST DISSOLVING STRIPS BY USING EZETAMIBE AS A MODEL DRUG." Indo American Journal of Pharmaceutical Sciences 05, no. 01 (2018): 85–91. https://doi.org/10.5281/zenodo.1135422.

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The oral mucosa is vascularized where by absorbed drugs get direct access to the systemic circulation without first pass metabolism. This present work is to formulate mouth dissolving film of Ezetamibe for enhanced bioavalibility. Drug and excipients studies were conducted using FTIR. Oral films of Ezetamibe were formulated using HPMC E5, as a film forming agent and propylene glycol as plasticize. And citricacid (salaviry stimulent), flavouring agents (vennila) are used.The solvent casting method was used for the preparation of films. Ezetamibe oral film was evaluated for folding endurance, th

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Pawar, Rajat, Ravi Sharma, and Gajanan Darwhekar. "Formulation and Evaluation of Mouth Dissolving Film of Prochlorperazine Maleate." Journal of Drug Delivery and Therapeutics 9, no. 6 (2019): 110–15. http://dx.doi.org/10.22270/jddt.v9i6.3679.

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This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Prochlorperazine maleate (used for the treatment nausea and vomiting) by formulating its mouth dissolving film (MDF). Prochlorperazine belongs to BCS II and oral bioavailability of it’s about 11-15%. The MDF of Prochlorperazine maleate was prepared by solvent casting method using HPMC (film forming agent),Glycerol (plasticizer), Betacyclodextrin (solubilizing agent), Citric acid (saliva stimulating agent), Mannitol (sweetening agent). The formulation was optimized by two factors, three levels

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Akhade, Bhavana, Vivekanand Chatap, Prashant Jain, and Mahesh Bhat. "Design, Development and Characterization of Ropinirole Mouth Dissolving Film by using Spin Coating Technique." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 13, no. 02 (2022): 516–21. http://dx.doi.org/10.25258/ijddt.13.2.10.

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The aim of the research was to develop a ropinirole mouth-dissolving film employing solvent casting and spin coating methods with sesbenia gum acting as a film-forming agent. Parkinson’s disease is treated with ropinirole. Sesbenia gum was designed as a film-forming ingredient in the 25 to 600 mg concentration range for solvent casting and 50 to 250 mg for spin coating. For both procedures, the concentration of the plasticizer propylene glycol was optimized between (0.3 and 1.0 mL). Film-forming agent and plasticizer effects at various concentrations were examined. For the solvent casting and

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