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Journal articles on the topic 'Mouth ulcer'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Rutuja, Jaiswal* Tejaswini Dhawale Dr. Gajanan Sanap. "Herbs Therapies for Mouth Ulcer." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 2493–501. https://doi.org/10.5281/zenodo.14524961.

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Ulcer is a common disorder which is seen among many people. In most cases, it is an inflammatory skin rupture. There are many types of ulcers such as mouth ulcer, peptic ulcer, oesophagus ulcer, gastric ulcer. Among these mouth ulcers is common type of ulcer. Throughout the ages, treat a variety of illnesses and diseases. Mouth ulcers or aphthous ulcers are common oral lesions characterized by painful, shallow sores on the mucous membranes. This abstract explores the causes, symptoms, and potential treatments for mouth ulcers, emphasizing their impact on oral health and quality of life. Nowada

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Salwa, Khalil and Khidir A.M. Hassan. "LIQUORICE MOUTH WASHES AS TREATMENT FOR MOUTH ULCER." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 02 (2018): 916–21. https://doi.org/10.5281/zenodo.1181462.

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Background: Mouth ulcer is small painful ulcers which typically have a red border and yellow-gray centres. Mouth ulcers can be treated by topical antihistamines, antacids, and corticosteroids. The purpose of this study is to formulate the liquorice as mouth wash and to assess if the liquorice is effective in treatment of mouth ulcer or not. Method: The liquorice was extracted and formulated as mouth wash. Clinical trial was done by applied the mouth wash to patients suffering from stomatitis mouth ulcer. The patients were followed up for three days. Results:In most cases, patients felt better

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Mihir Makwana, Mihir Makwana, Prof Hiral S. Popaniya Prof. Hiral S. Popaniya, Dr Payal Vaja Dr. Payal Vaja, Smruti Sankhat Smruti Sankhat, and Vadariya Priya Vadariya Priya. "A Systematic Review of Herbal Approaches for Mouth Ulcer Management." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 1759–68. https://doi.org/10.35629/4494-100217591768.

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The mouth ulcer is common disorder caused by various etiological factor. These oral ulcers, often referred to as tiny sores, are painful lesions that typically appear along the gum line inside the mouth. They frequently cause discomfort and pain. Which can influence a person’s food choices during the healing process. The aim of this work is to evaluate the effectiveness and safety of different herbal remedies for treating and managing mouth ulcer. Numerous formulations, both synthetic and natural, are available on the market. Herbal remedies play a crucial role in primary healthcare due to its

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Pathan, Irfan Mustafa, Vishal S. Madankar, and Anil B. Panchal. "Formulation and Evaluation of Guava Leaf-Based Nanogel for Mouth Ulcer Treatment." Journal of Drug Delivery and Therapeutics 15, no. 4 (2025): 13–19. https://doi.org/10.22270/jddt.v15i4.7069.

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Mouth ulcers, also known as aphthous ulcers, are painful lesions affecting the oral mucosa, causing discomfort and irritation. Conventional treatments, such as antiseptic gels and corticosteroids, provide temporary relief but may have side effects with prolonged use. Guava leaves (Psidium guajava) contain bioactive compounds such as flavonoids, tannins, and polyphenols, which exhibit antimicrobial, anti-inflammatory, and wound-healing properties. This study focuses on the formulation of a simple, Nanogel using Carbopol 934 as a base for the treatment of mouth ulcers. The gel was prepared by in

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Vidya, S. "Just a mouth ulcer?" British Dental Journal 202, no. 10 (2007): 584. http://dx.doi.org/10.1038/bdj.2007.437.

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Anushree, Tiwari. "Aphthous Ulcer: A Case Report." People's Journal of Scientific Research 16, no. 1 (2023): 1–3. https://doi.org/10.5281/zenodo.8077187.

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Mouth ulcers are quite common in all age groups. They can be linked to several conditions such as simple injury due to acute trauma or due to a sharp tooth or to an autoimmune disease. There are several medications available on the market to treat mouth ulcers. But do we need to prescribe a medication every time? This report presents a case of a 34-year-old male who presented with an ulcer in the palate and was treated without a prescription.

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Sruthi R, Sruthi R., and Merin Levy Philips. "Unveiling risks: Navigating adverse drug reactions in leflunomide therapy." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 111–15. https://doi.org/10.35629/4494-0906111115.

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We report a case of a 55-year-old female patient who developed oral ulcer, headache, and hepatomegaly after she started therapy with leflunomide. It was about nine years back that she was diagnosed with Rheumatoid Arthritis. Her earlier history states that she was on tablet Leflunomide 10mg 4years back and she had stopped it.Later decided to continue leflunomide as the part of treatment protocol. After the starting of treatment, she was presented with mouth ulcers in one month of time. She had hepatomegaly, grade 2 fatty liver, cystitis, umblical hernia on USG. She showed features suggestive o

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Gondkar, Sanika Sanjay. "Therapeutic Potential of Jasmine Herbal Lozenges in the Treatment of Recurrent Aphthous Stomatitis." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 5170–79. https://doi.org/10.22214/ijraset.2025.71397.

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Mouth ulcers, also known as aphthous ulcers, are common inflammatory lesions that affect the mucous membranes of the oral cavity. They can cause significant discomfort, pain, and difficulty in eating, drinking, and speaking. Conventional treatments, such as topical corticosteroids and antiseptic gels, often provide temporary relief and may have undesirable side effects. In response to the growing demand for safe and effective natural remedies, this study focuses on the formulation and evaluation of herbal lozenges containing Jasminum sambac (jasmine) extract for the treatment of mouth ulcers.

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Tumme, Dhanashri Mahesh, and Samruddhi Suresh Rajurkar. "A Review of novel combination therapy for mouth ulcer therapy." Journal of Drug Delivery and Therapeutics 15, no. 4 (2025): 242–47. https://doi.org/10.22270/jddt.v15i4.7092.

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Mouth ulcers are a common and debilitating condition affecting millions worldwide. Conventional treatments often provide symptomatic relief but may have limitations and side effects. This review explores the potential of a combination therapy using Jasminum grandiflorum (jasmine) and Ocimum tenuiflorum (Tulsi) for mouth ulcer recovery. Both plants have been used in traditional medicine for their anti-inflammatory, antimicrobial, and wound-healing properties. The review discusses the therapeutic properties of each plant, their potential synergistic effects, and the various formulation options a

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Knecht, Kenneth, and Yehia Y. Mishriki. "More than a mouth ulcer." Postgraduate Medicine 105, no. 5 (1999): 200–203. http://dx.doi.org/10.3810/pgm.1999.05.1.764.

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Shubham, Tomar* Akash Gorase Prathamesh Ware Krushna Jagzap Rushikesh Shinde. "Formulation and Evaluation of Herbal Mouth Ulcer Gel by Utilizing Psidium Guajava and Jasminum Officinale." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 351–67. https://doi.org/10.5281/zenodo.15581547.

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This study addresses the formulation and evaluation of Herbal mouth ulcer gel containing extracts of Psidium Guajava and Jasminum officinale. The herbal mouth ulcer gel is Formulation using leaves of Psidium Guajava and Jasminum officinale. The Extraction of Guava and Jasmine leaves is Prepared by Ethanolic Extraction and herbal mouth ulcer gel is Prepared by Compounding Method. The herbal mouth ulcer gel formulation was prepared by using guava leaf extract, jasmine leaf extract, Carbopol 934, methyl paraben and propyl paraben, Triethanolamine and required amount of distilled water. &nbsp

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Patil, Vrushali, Utkarsha Shivsharan, and Ravikant Patil. "Formulation and evaluation of guava leaf extract gel for mouth ulcer management." Indian Journal of Pharmacy and Pharmacology 9, no. 4 (2022): 247–51. http://dx.doi.org/10.18231/j.ijpp.2022.045.

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The highlight of this study was preparation of microparticles using the extract of guava leaves which led to novel drug delivery of the herbal extract. The aim of the study was to formulate a microparticles loaded gel for management of mouth ulcer. The microparticles were prepared by solvent evaporation method using the polymer, oil and liquid phase. Then the preparation of gel base was done with incorporation of microparticles. The evaluation of the microparticles and the gel was done. This study is an effort to develop a herbal gel for mouth ulcers offering better compatibility and lesser di

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Safdar, Dilnasheen, and Rehana Panjawani. "Evaluation of effective strategies in the prevention of chemotherapy induced mucositis among Children." Journal of the Pediatric Infectious Diseases Society 13, Supplement_4 (2024): 23–24. http://dx.doi.org/10.1093/jpids/piae093.065.

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Abstract Background Oral mucositis is a frequent side effect of anticancer treatments. It impairs the patient’s quality of life, aggravate clinical condition, increase the risk of infection and can delay anticancer treatment. Health care workers at the NIBD and BMT Karachi, Pakistan emphasize on oral hygiene to prevent such complications for the patients. Proper oral hygiene protocol can reduce the risk of oral ulcers. In this study we have done the evaluation of oral hygiene. At NIBD and BMT among pediatric population are advice to brush their teeth twice a day, use pyodine/ Chlorhexidine 0.2

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Ghadge, Dnyaneshwari* Pachpute Sayli Agalave Vaishnavi Kamble Rachana. "Mouth Ulcer Management via Oral Films: A Critical Review of Formulation, Evaluation, and Future Directions." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 3129–35. https://doi.org/10.5281/zenodo.15284413.

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Mouth ulcers are a widespread and debilitating condition. Recent research suggests that riboflavin, a B-complex vitamin, may offer a promising treatment option due to its antioxidant and anti-inflammatory effects. This review delves into the development and efficacy of riboflavin oral films, a novel delivery system that enhances bioavailability and targets the affected area. We summarize the current research on riboflavin oral films, discussing their benefits, challenges, and therapeutic potential in treating mouth ulcers. This comprehensive review serves as a valuable resource for researchers

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Vashishat, Bhart, Shruti Sinha, Tanmay Srivastava, et al. "Management of oral aphthous ulcer: A review." Bioinformation 20, no. 5 (2024): 434–38. http://dx.doi.org/10.6026/973206300200434.

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Aphthous ulcers, also known as canker sores, are a common oral condition characterized by recurrent, painful, small ulcers that typically arise on the non-keratinized mucous membranes within the mouth. Although the pathogenesis of aphthous ulcers is not completely understood; it is believed to be involved in a combination of genetic predisposition, local trauma, stress, hormonal changes, and certain environmental factors. Thus, management of aphthous ulcer revolves around reducing pain, promoting healing and preventing recurrence.

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Sachin, Bhale* Priya Jaware Prachi Murkute Ashwini Pundkar Santosh Payghan. "Formulation and Evaluation of Herbal Mouth Gel." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 1522–34. https://doi.org/10.5281/zenodo.15380314.

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Ulcers are most common in the oral region, for which the patient seeks help from their Physician/dental surgeon. The presenting complaints are usually redness, burning, Sensation and/or pain. They can present in any part of the oral cavity but may be painful if it occurs in the movable area. Mouth ulcers cause pain and irritation from salty, spicy, and sour food items and may Cause discomfort while healing occurs due to the use of chemical formulations. This project Focuses on the preparation of an herbal mouth ulcer gel because it has fewer side effects. The gel was prepared by using guava le

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Murkute, Vishal* Dr. Datkhile S. V. "Formulation And Evaluation of Antiulcer Gel Using Extract of Spathodea Campanulata P. BEAUV." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 1077–80. https://doi.org/10.5281/zenodo.15605571.

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Spathodea Campanulata is a medicinal plant known for its potent antioxidant, anti-inflammatory, and gastroprotective properties. The present study focuses on the formulation and evaluation of an herbal antiulcer gel using extract for the treatment of oral ulcers. The bioactive compounds, including flavonoids, tannins, and alkaloids, contribute to its ulcer-healing potential by promoting tissue regeneration and reducing inflammation. The gel was formulated using a suitable polymer base, ensuring optimal viscosity, spreadability, and adherence to the oral mucosa. Various concentrations of extrac

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18

Unur, M., D. Ofluoglu, M. Koray, G. Mumcu, A. E. Onal, and H. Tanyeri. "Comparison of a New Medicinal Plant Extract and Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis." Balkan Journal of Dental Medicine 18, no. 1 (2014): 29–34. http://dx.doi.org/10.1515/bjdm-2015-0004.

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Abstract The aim of this study was to evaluate the effectiveness of a new medicinal plant extract (Ankaferd Blood Stopper®, ABS) on the healing process of aphthous ulcers. A total of 50 patients with recurrent aphthous stomatitis (RAS) who have had currently a single oral ulcer in the mouth were included in the study. Patients were randomly divided in 2 groups: ABS group and Kenacort group (triamcinolone acetonid). Data were collected by questionnaire regarding age, gender, RAS history including the number of ulcer episodes in 1 month, the number of ulcers in each episode, mean healing time of

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Babu, K. Anand, and R. Ram Narayanan. "A Review on unexplored Plants for Recurrent Aphthous Stomatitis." International Journal of PharmTech Research 13, no. 3 (2020): 253–60. http://dx.doi.org/10.20902/ijptr.2019.130316.

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Recurrent Aphthous Stomatitis (RAS) is one of the most common pathological conditions with ulcers in the oral mucosa. Various conventional medicines are available in the market for RAS but due to a range of factors people are getting affected by RAS gradually. More over conventional medicines are all having the side effects so the alternative system for the treatment of RAS came in to the market. Although herbal medicines are widely used in India and other countries and multiple studies are conducted in this regard, but still many of the herbal plants are not utilized though they are having tr

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Dattatray, Thevarkar Shreya, and Sonali S. Sonawane. "A Review on: Herbs Used in Treatment of Mouth Ulcer." International Journal of Research Publication and Reviews 5, no. 4 (2024): 4582–93. http://dx.doi.org/10.55248/gengpi.5.0424.1044.

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K. Mishra, Nikunja, Uma Mudi, Jyotirmayee Behera, and Amiyakanta Mishra. "INVESTIGATING THE EFFECTS OF POLYHERBAL GEL ON PHENOL-INDUCED ORAL APHTHOUS ULCERS IN RATS." INDIAN DRUGS 62, no. 02 (2025): 78–85. https://doi.org/10.53879/id.62.02.15037.

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Aphthous ulcers, commonly known as canker sores, are among the most widespread oral diseases globally. They typically occur on the non-keratinized mucosal surfaces inside the mouth, including the inner lips, floor of the mouth, and the underside of the tongue. Herbal therapy plays an important role in the healing process of diseases without causing any significant side effects. This study investigates the effects of polyherbal gel (PHG) on phenol-induced oral aphthous ulcers in rats. The rats were randomly assigned to five experimental groups; PHG 5%, 10% and 20% w/V were administered topicall

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Kumar, Hitesh. "Formulation & Evaluation of Aqueous Guava & Babul Leaves for the Treatment of Mouth Ulcer." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 05 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem34893.

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This study delved the development and evaluation of a new herbal gel for mouth ulcers using pulverized guava leaves. The gel incorporated colorful attention of the leaves with Carbopol 934 and Propylene glycol as a base. Evaluation included assessments of the gel's physical parcels and natural exertion. Infrared spectroscopy verified no adverse commerce between the leaves and the gelatinizing agent. The performing gel was transparent, invariant, and had a neutral pH range( 7- 7.5). also, it demonstrated good rheological parcels, spreading and banishing fluently. Anti- fungal tests revealed sig

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Nikita, Kor1 Pradnya Tarmale2 Vaibhavi Vishe3 Pratiksha Sonawane4. "Formulation And Evaluation of Herbal Mouth Ulcer Gel." International Journal of Pharmaceutical Sciences 3, no. 6 (2025): 846–53. https://doi.org/10.5281/zenodo.15597838.

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The current study focuses on the "Formulation and Evaluation of a Herbal Gel" that combines natural substances with therapeutic capabilities to heal mouth ulcers. Selected herbes such as Guava, Polyalthia longifolia, Curcuma longa (turmeric), Aloe vera, Capsicum were incorporated due to their anti-inflammatory, antimicrobial, and wound-healing activities. The gel was prepared using a suitable gelling agent to ensure appropriate consistency and ease of application. Physical parameters like pH, spreadability, viscosity, and stability were evaluated. The gel exhibited satisfactory physical charac

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Jaydeep, Mr Pawar, Mr Yalse Manoj, and Sonwane Sumit. "Turmeric-Based Mouth Dissolving Film for Ulcer Treatment." International Journal of Research in Pharmacy and Allied Science 04, no. 02 (2025): 115–18. https://doi.org/10.71431/ijrpas.2025.4211.

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This study explores the formulation and evaluation of a turmeric-based mouth dissolving film (MDF) designed for ulcer treatment. Turmeric, known for its active compound curcumin, possesses anti-inflammatory and antimicrobial properties that can aid in ulcer healing. The MDF provides a convenient and effective mode of drug delivery, ensuring rapid disintegration and absorption. The study involves formulation, characterization, and in vitro evaluation of the film, assessing parameters like tensile strength, disintegration time, and drug release profile. Results indicate enhanced curcumin bioavai

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S., S. Chavan V. D. Thombare B. Shejul*. "Development And Evaluation Of Herbal Oral Gel Containing Extract Of Polyalthia Longifolia Leaves For The Treatment Of Mouth Ulcers." International Journal in Pharmaceutical Sciences 1, no. 12 (2023): 389–403. https://doi.org/10.5281/zenodo.10389752.

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The mouth ulcers are round or oval sores which give rise to redness, pain and discomfort leading to alteration of person food choice while healing process. Aphthous stomatitis and Local trauma are the most common types of oral ulcers. The aim of present study was to formulate and evaluate herbal oral gel of Polyalthia longifolia leaves extract for treatment of mouth ulcer. Polyalthia longifolia leave has been usually used to govern diseases such as treat fever, gonorrhoea, uterus ailments, mouth ulcer, heart problems and it also possesses good antimicrobial, antifungal, antibacterial activity,

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Chinu, Kumari Dev Prakash Dahiya Nikhil Rana Kanika Rahul Sharma*. "EXPLORING THE POTENTIALS OF COLEBROOKEA OPPOSITIFOLIA FOR TREATEMENT OF MOUTH ULCERS." International Journal in Pharmaceutical Sciences 2, no. 4 (2024): 848–55. https://doi.org/10.5281/zenodo.11000613.

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Mouth ulcers are a common, painful condition that can have a detrimental effect on one's quality of life. The creation of novel treatments derived from natural sources, such as plant extracts and phytochemicals, is gaining popularity. One such plant that has shown promise for therapeutic effects but has not received enough attention is Colebrookea oppositifolia. The current status of research on C. oppositifolia is outlined in this review, along with an assessment of the plant's potential for use as an integrative medicine to treat mouth ulcers. The goal of future studies should be to clarify

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Potra-Cicalău, G. I., I. Scrobotă, G. Iova, L. Todor, G. Ciavoi, and R. C. Iurcov. "Recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS) enigmatic etiopathology." Medicine in Evolution 29, no. 2 (2023): 136–41. http://dx.doi.org/10.70921/medev.v29i2.1011.

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Oral aphthous ulcer is a well-known condition that significantly affects the quality of life for patients by producing intense pain and difficulties in speaking and chewing. When recurrence is present we refer to them as recurrent aphthous ulcers (RAU) and recurrent aphthous stomatitis (RAS). Mouth ulcers are typically uncomfortable sores that can occur as a result of a variety of local and general disorders. It is one of the most prevalent oral ulcerative conditions.

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Lv, Xiaoying, and Yaxiong Guo. "Research Progress on Traditional Chinese Medicine Treatment of Recurrent Oral Ulcers in Children." Journal of Contemporary Medical Practice 7, no. 1 (2025): 197–200. https://doi.org/10.53469/jcmp.2025.07(01).37.

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Objective: To analyze and discuss the treatment of recurrent oral ulcers with traditional Chinese medicine (TCM), in order to provide a reference for the treatment of recurrent oral ulcers and other related oral diseases with TCM in the future. Methods: The key words “recurrent oral ulcers in children” or “recurrent aphthous ulcers in children” and the Chinese medical names “aphthous ulcers”, “aphthous ulcers”, “mouth ulcer”, “mouth erosion”, etc., and secondary searches with “Chinese medicine”, “combination of Chinese and Western medicine”, etc. were performed. A secondary search with “Chines

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Ankit, P. Gondane *. Sayali V. Thote Tejaswini C. Chandel Vedika A. Kumarwar Harshita D. Bansod. "Formulation and evaluation of Herbal Mouth gel Containing Clove and Myrrh." International Journal in Pharmaceutical Sciences 3, no. 4 (2024): 694–704. https://doi.org/10.5281/zenodo.10964940.

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Clove is known as aromatic medicinal herb since ancient time. The extraction of essential oil and the chemical composition of oil from clove are describe along with antimicrobial, insecticidal, antifungal and other uses. clove oil has several benefits and is consider one of the most effective in mouth ulcer treatment.   Myrrh is used to reduce pain and kill bacteria. Myrrh preparation can be used for treatment of ulcer and inflammation in the mouth and for minor wounds.  Myrrh shows various medicinal activity such as it is used in diarrhea, parasite infection, wound healing, and

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Hubka, Joanna, Kinga Grużewska-Piotrowska, Agnieszka Grużewska, Monika Pająk, and Wojciech Wcisło. "Riga-Fede disease: report of a case in an infant." Journal of Education, Health and Sport 46, no. 1 (2023): 273–82. http://dx.doi.org/10.12775/jehs.2023.46.01.019.

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Riga-Fede disease (RFD) is a rare, benign condition found in infants, characterized by ulcers in the oral mucosa, around the tongue and gums. It is caused by repeated injuries, caused by movements of the tongue over the lower incisors. It usually coexists with neonatal teeth. Although it starts as a small ulcer, it can progress to a large fibrous lesion. Symptoms include pain, swelling and difficulty swallowing and sucking. Early diagnosis and treatment are important to prevent late complications, including insufficient food intake, growth retardation and deformity of the tongue, gums, lips an

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Aarati, Shedage* Saloni Palve Santoshi Mehetre Jyoti Salgar. "Formulation And Assessment of Oral Gel for The Treatment of Mouth Ulcer Using Extract from Jamun Seed Powder." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3457–67. https://doi.org/10.5281/zenodo.15475370.

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The majority of the world's population, particularly in developing nations, still relies on herbal medicines for primary health care because they are more culturally acceptable, more compatible with the human body, and have fewer adverse effects. Herbal treatments are made from a plant or its components and are used to cure ailments, diseases, and injuries, as well as to promote health and healing. People are now more conscious of the side effects and the ingredients used in the preparation of gels and other formulations. In the Unani and Ayurvedic health systems, the native Indian Jamun (Syzy

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Sandra, P.* Safa P. K. Femina Arippayil Arun Prakash K. V. Hiba Musthafa K. P. Nandana P. "Anticancer Activity of Coleus Amboinicus." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 251–62. https://doi.org/10.5281/zenodo.15332193.

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Ulcers are most common in the oral region, for which the patient seeks help from their Physician/dental surgeon. The presenting complaints are usually redness, burning, Sensation and/or pain. They can present in any part of the oral cavity but may be painful if it occurs in the movable area. Mouth ulcers cause pain and irritation from salty, spicy, and sour food items and may Cause discomfort while healing occurs due to the use of chemical formulations. This project Focuses on the preparation of an herbal mouth ulcer gel because it has fewer side effects. The gel was prepared by using guava le

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Upadhye, K., K. Charde, G. Dixit, and S. Bakhle. "Formulation and evaluation of herbal gel for management of mouth ulcers." Indian Journal of Pharmacy and Pharmacology 8, no. 3 (2021): 226–30. http://dx.doi.org/10.18231/j.ijpp.2021.039.

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: or mouth ulcers is the most common condition that we encounter. Clinically the lesions are single or multiple superficial and deep sealed and are associated with microbial invasions.: This study was conducted with the aim of evaluating the effectiveness of herbal drugs for treatment of In the research work, mouth ulcer gels were formulated incorporating the extracts of as and using 934 as the gelling agent. Seven batches were formulated by varying the concentration of the herbal ingredients (F1 to F7)The prepared formulations were evaluated for various parameters like physical appearance, pH

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Septiyan, Taufik, Gofarana Wilar, and Nasrul Wathoni. "Herbal Medication of Recurrent Aphthous Stomatitis: A Narrative Review." Bioscientia Medicina : Journal of Biomedicine and Translational Research 6, no. 1 (2021): 1318–23. http://dx.doi.org/10.37275/bsm.v6i1.438.

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A mouth ulcer or recurrent aphthous stomatitis (RAS) is a mouth mucous tissue inflammation. This disease mainly occurs in patients 10-40 years of age, preferably in women and high socioeconomic backgrounds. The cause of mouth ulcers or RAS could be trauma, infection, digestive problems, or blood disorders. Herbal practitioners widely use herbs, folks, and society to treat various diseases. This research aimed to describe the herbal treatment for RAS. The review results show there are nine plants with the ability to cure RAS, they are Persea americana Mill., Averrhoa bilimbi L., Abrus precatori

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Sambhaji Pagare, Ms Indrayani, and Mr Utkarsh Ravindra Mandage. "Formulation, Evaluation and Anti-Bacterial Activity of Herbal Gel for Mouth Ulcer by Using Jasminum Officinale." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 09, no. 03 (2025): 1–9. https://doi.org/10.55041/ijsrem42498.

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Mouth ulcers are a common oral condition causing discomfort and affecting daily life. The present study focuses on the formulation, evaluation, and anti-bacterial activity of a herbal gel using Jasminum officinale (common jasmine), a plant known for its medicinal properties. The plant contains a variety of bioactive compounds, including alkaloids, flavonoids, tannins, and essential oils, which contribute to its anti-inflammatory, antioxidant, and antibacterial effects. The herbal gel was formulated by extracting active ingredients from Jasminum officinale and incorporating them into a gel base

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Kuraitby, Shahed, Alaa ALhomsi, and Abeer A. Aljoujou. "Effectiveness of combination the photobiomodulation therapy and triamcinolone acetonide on managing oral major aphthous ulcer in Crohn’s disease: A case report." Medicine 104, no. 29 (2025): e43336. https://doi.org/10.1097/md.0000000000043336.

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Rationale: Inflammatory bowel diseases like Crohn’s disease can manifest with oral ulcers that negatively impact quality of life. Managing these stubborn symptomatic lesions requires an integrated medical and dental approach. Patient concerns: A 23-year-old male was diagnosed with Crohn’s disease 3 years ago. He was referred to the oral medicine department due to a painful 3 cm ulcer on the dorsum of the tip of his tongue, which was interfering with his ability to eat and drink. Diagnoses: A gastrointestinal endoscopy revealed a rectal ulcer, a cecal ulcer, superficial erosion, and scattered m

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Anggraeni, Dian, Kamaluddin Kamaluddin, and Theodorus Theodorus. "Effectiveness of Garlic Water Extract Gel (Allium sativum. L) Against Necrotic Factor Alfa Tumors and Mouth Ulcer Diameter in Wistar White Male Rats." Biomedical Journal of Indonesia 6, no. 1 (2020): 27–34. http://dx.doi.org/10.32539/bji.v6i1.7970.

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Oral ulcers are pathological conditions that are characterized by loss of epithelial tissue, causing inflammation. During inflammation, the inflammatory mediator is TNF will increase. Therefore, drugs are needed to suppress TNF-levels to suppress inflammation. One of the herbal ingredients that can suppress inflammation is garlic. In vivo laboratory experimental research with pre-post systems. The samples used were 36 male Wistar white rats divided into 6 groups (6 individuals / groups), namely the group without drug treatment (as pre-treatment data), negative control group namely HPMC gel bas

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Pandya, Maitreyi, Anupama N. Kalappanavar, Rajeshwari G. Annigeri, and Dhanya S. Rao. "Relative Efficacy of Quercetin Compared with Benzydamine Hydrochloride in Minor Aphthae: A Prospective, Parallel, Double Blind, Active Control, Preliminary Study." International Journal of Dentistry 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/7034390.

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Background and Objectives. Recurrent aphthous stomatitis is an inflammatory condition present since ancient era wherein numerous treatment modalities have been tried. But complete eradication of the disease has not been possible and hence newer agents are being introduced. One such agent is a flavonoid named quercetin with proven antioxidant, anti-inflammatory, and ulcer healing properties. Methods. 40 patients with minor aphthous ulcers were divided equally into two groups: A and B. Group A patients were advised to apply quercetin gel and Group B patients were advised to take benzydamine hydr

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Elnaqa, Farah. "A textbook example of a cancerous mouth ulcer." BDJ Team 8, no. 4 (2021): 38–39. http://dx.doi.org/10.1038/s41407-021-0581-4.

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Shah, Shivani, Padmasayee Papineni, Ala Ibrahim Elhbishi, and Sana Rivzi. "15 A man with a painful mouth ulcer." Clinical Infection in Practice 20 (December 2023): 100282. http://dx.doi.org/10.1016/j.clinpr.2023.100282.

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Elhabal, Sammar Fathy, Ahmed Mohsen Faheem, Sandra Hababeh, et al. "Augmented Marshmallow Extract Lipid Nanoparticles with Clove Oil Embedded in Collagen Sponge for Ultimate Antimicrobial Healing of Diabetic Mouth Ulcer." Pharmaceutics 17, no. 5 (2025): 611. https://doi.org/10.3390/pharmaceutics17050611.

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Background/Objectives: Diabetic mouth ulcers are a pathological condition of the oral mucosa leading to increases in susceptibility to infection and prolonged wound healing time. Still, there is a lack of natural formulations for treating this condition. Our principal objective was to formulate solid lipid nanoparticles (SLNs) that contained Althaea officinalis (marshmallow) (M.) extract with clove oil (CO.), subsequently integrated into a collagen sponge for enhancing stability, solubility, sustained release, antimicrobial efficacy, and healing power when targeting diabetic oral ulcers. Metho

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N Nayak Shruthi, Ananya. "DNA Barcoding, Phytochemical Analysis of Basella Alba and its Correlation with Mouth Ulcer." International Journal of Science and Research (IJSR) 12, no. 3 (2023): 805–12. http://dx.doi.org/10.21275/sr23309230252.

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Khunta, Yash, Meet Morad, Yash Vasoya, et al. "Formulation and Characterization of a Mouth Ulcer Spray: Stability, Safety, and Therapeutic Potential." International Journal of Research Publication and Reviews 6, no. 3 (2025): 6499–502. https://doi.org/10.55248/gengpi.6.0325.12101.

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S. Altaei, Tagreed, Intesar T. Numan, Saad A.Hussain, and Nazar G. Al-Talabani. "The Efficacy of Topically Applied Silymarin in the Treatment of Herpes Labialis Ulcers." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 16, no. 1 (2017): 39–46. http://dx.doi.org/10.31351/vol16iss1pp39-46.

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Herpes labialis is an infection caused by the herpes simplex virus, characterized by an eruption of small and usually painful blisters on the skin of the lips, mouth, gums, or the skin around the mouth. Although there is no successful treatment available, the local use of compounds with effective anti-inflammatory and cytoprotective effects may be of value in this respect. This project was designed to evaluate clinically the local use of silymarin, a group of flavonoids with powerful antioxidant, anti-inflammatory and cytoprotective activity, in the treatment of herpes simplex ulcer. Fifty thr

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Assiri, Hassan A., Ashwaq B. Majrashi, Reema K. Alqarni, and Mohammad S. Hameed. "Management of Concurrent Presentation of Aphthous Ulcer Major and Herpes Labialis." King Khalid University Journal of Health Sciences 10, no. 1 (2025): 88–91. https://doi.org/10.4103/kkujhs.kkujhs_31_24.

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Abstract Aphthous ulcers and herpes labialis (HL) are prevalent oral conditions, each with distinct origins and clinical appearances. Major aphthous ulcers, a variant of RAS, are less frequent and present as large recurrent, painful sores on the mucous membranes of the mouth, typically lacking a viral cause; their etiology appears to be multifactorial. In contrast, HL results from the reactivation of the herpes simplex virus, leading to clusters of vesicles primarily around the lip area. The co-occurrence of these conditions is unusual and can complicate both diagnosis and treatment due to the

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Alotaibi, Turki Nasser, Ahmed Mufadhi Alanazi, Manahil Abdulaziz Alnafea, et al. "Knowledge and Attitude about Oral Cancer and Treatment Seeking Behavior in Saudi Arabia." International Journal of Cancer Research & Therapy 9, no. 2 (2024): 01–07. https://doi.org/10.33140/ijcrt.09.02.10.

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Oral cancer is an accelerated and uncontrolled growth of cells in some oral mucosa; it can occur inside the cheeks, under the middle of the tongue or at the front of the tongue, or on the lining of the tissue in the mouth or gums.There are signs and causes of oral cancer that should be well known and we can detect early, which is a determining factor in the treatment of any type of cancer [1]. If there are signs in the mouth, go to the doctor immediately for early treatment, according to medical news todaysuch as difficulty chewing or swallowing, the presence of bumps or ulcers in the mouth, l

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Cebeci, Dua, İlkay Can, and Görgün Bayraktaroğlu. "Orf Mimicking a Venous Ulcer in the Foot." Journal of Global Infectious Diseases 15, no. 3 (2023): 127–29. http://dx.doi.org/10.4103/jgid.jgid_158_22.

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Orf virus is a DNA virus belonging to the parapoxvirus family which is transmitted to humans by zoonotic routes through contact with infected animals. It is a worldwide spreading pathogen that can cause significant financial losses in animal production. Here, we present the case of a 42-year-old man diagnosed with orf but presenting as a venous ulcer in his on the inside of the left foot. He had been caring for his neighbor’s sheeps which had been recently ill with “sore mouth.” This case draws attention to the fact that orf should be included in the differential diagnosis of patients presenti

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Zgažarová, Lucie. "Mouth ulcer as a side effect of methotrexate therapy." Dermatologie pro praxi 14, no. 1 (2020): 36–38. http://dx.doi.org/10.36290/der.2020.002.

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MILANI, Vanessa, Lincoln Lara Cardoso, Andrezza do Carmo Santos, Filipe Moreira Biokino, Eneida Franco Vêncio, and Rejane Faria Ribeiro-Rotta. "EOSINOPHILIC ULCER MIMICKING FLOOR OF MOUTH SQUAMOUS CELL CARCINOMA." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 136, no. 1 (2023): e83. http://dx.doi.org/10.1016/j.oooo.2023.03.307.

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Somesh, O. Kale1* Ashvini B. Deshmukh2. "Polyherbal Gel For Management Of Mouth Ulcer: A Review." International Journal in Pharmaceutical Sciences 2, no. 5 (2024): 247–53. https://doi.org/10.5281/zenodo.11127319.

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The main purpose of this gel formulation of Guava leaves, Neem leaves, Mango leaves, Jasmine leaves, Jamun leaves was to relieve pain and discomfort due to oral ulcers. As we know there are different types of sores in the mouth that cause inflammation and pain. The most common oral ulcers are Local trauma & Aphthous Stomatitis. Now many over-the-counter medications are essential to staying in primary health care because of the positive response and the most effective treatment with the least amount of side effects. Herbal medicines are still the backbone of almost 75-80% of the world's pop

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