Academic literature on the topic 'Mouthwashes Chlorhexidine'
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Journal articles on the topic "Mouthwashes Chlorhexidine"
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Murthy Kumar, Karthikeyan. "Views on antioxidant mouth washes as adjunct in periodontal therapy." Bioinformation 16, no. 12 (December 31, 2020): 1069–79. http://dx.doi.org/10.6026/973206300161069.
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Clinical decision is often difficult with chlorhexidine mouthwash. The use of antioxidant mouthwashes for the treatment of periodontal disease is in practise. Therefore, it is of interest to collect gleaned information on Antioxidant mouthwashes as periodontal therapy from known literature. Improvement in treatment using antioxidant mouthwashes is reported in several studies. The mouthwash with antioxidants has similar anti-gingivitis, antiplaque and antimicrobial effects as that of chlorhexidine mouthwash.
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Murthy Kumar, Karthikeyan. "Views on antioxidant mouth washes as adjunct in periodontal therapy." Bioinformation 16, no. 12 (December 31, 2020): 1069–79. http://dx.doi.org/10.6026/973206300161069.
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Clinical decision is often difficult with chlorhexidine mouthwash. The use of antioxidant mouthwashes for the treatment of periodontal disease is in practise. Therefore, it is of interest to collect gleaned information on Antioxidant mouthwashes as periodontal therapy from known literature. Improvement in treatment using antioxidant mouthwashes is reported in several studies. The mouthwash with antioxidants has similar anti-gingivitis, antiplaque and antimicrobial effects as that of chlorhexidine mouthwash.
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Selvakumar, Renuka, and Muralidharan Np. "COMPARISON IN BENEFITS OF HERBAL MOUTHWASHES WITH CHLORHEXIDINE MOUTHWASH: A REVIEW." Asian Journal of Pharmaceutical and Clinical Research 10, no. 2 (February 1, 2017): 3. http://dx.doi.org/10.22159/ajpcr.2017.v10i2.13304.
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Objective: To discuss the benefits of herbal mouthwashes with the standard chlorhexidine mouthwash. This review is conducted to explore the benefits of herbal mouthwashes.Methods: Many herbal extracts are now available as mouthwash for maintaining the good oral hygiene. Plaque accumulation and increase in oral micro- organisms are the main factors for poor oral hygiene. Herbal extracts such as German chamomile, Terminalia chebula, Aloe vera, Green tea, peppermint satva, turmeric, neem, triphala, pomegranate extracts, guava extract, propolis, alum, darim leaves, mulethi, etc., are similar to chlorhexidine in plaque control and gingivitis reduction. Many herbal mouthwashes contain herbs with anti-microbial property such as neem, yavani satva, nagavalli, Gandhapura taila, pilu, Bibhitaka, Ocimum, Echinacea, Chameli leaves, etc. Many herbs are with anti-inflammatory and anti-oxidant property such as neem, clove, triphala (combination of amalaki, haritaki, and vibhitaki), tulsi, grapefruit, celery, licorice, katha, spearmint, and chamomile essential oil. Some herbal mouthwash with chamomile extract kills some skin pathogens such as staphylococcus and Candida species. Mixture of Staphysagria, Chamomilla, Echinacea, Plantago, Ocimum, and Cistus extracts used as mouth wash which was is better than chlorhexidine in reducing salivary mutans streptococcicount. Hence usage of herbal mouthwash will enhance the oral hygiene comparatively with chlorhexidine mouthwash without any adverse effects. Result: Though herbal mouthwashes has the ability to maintain good oral hygiene on daily basis, but still it is less effective than chlorhexidine mouthwash during treatments like gingivitis, periodontitis, trauma, etc. Conclusion: Besides the disadvantages, chlorhexidine mouthwash plays effective role during dental treatments on short term usage. Herbal mouthwashes are suitable for maintaining good oral prophylaxis. Many programs have to be conducted to make them aware about mouthwashes in their oral hygiene.Keywords: Chlorhexidine, Herbal, Mouthwash, Oral hygiene, Prophylaxis.
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Yaghini, Jaber, Narges Naghsh, Sayed Mohsen Sadeghi, and Samaneh Soltani. "Gingival Inflammatory Indices and Dental Stain Index after Using Aloe Vera-Green Tea Mouthwash, Matrica Mouthwash, or 0.2% Chlorhexidine Mouthwash Compared with Placebo in Patients with Gingival Inflammation." Open Dentistry Journal 13, no. 1 (June 30, 2019): 214–20. http://dx.doi.org/10.2174/1874210601913010214.
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Introduction: The purpose of this study was to evaluate and compare the effects of composition of aloe vera-green tea, matrica, and chlorhexidine on gingival inflammatory indices and dental stain index. Materials & Methods: In this double-blinded placebo-controlled clinical trial, anti-inflammatory, anti-plaque formation, and dental staining effects of two herbal mouthwashes, including aloe vera-green tea and matrica in comparison with chlorhexidine in 60 patients with plaque induced gingivitis referring to Isfahan University of Medical Sciences, School of Dentistry were evaluated. The indices evaluated in this study were plaque index (Silness and Loe), gingival index (Loe and Silness), bleeding on probing index (Ainamo and Bay) and dental stain index (Lobene stain index). They were evaluated on the first day of using mouthwashes and two weeks later. The obtained data were analyzed using SPSS software version 22. One-way ANOVA, Tukey post hoc, and paired t and Chi-square tests (α=0.05) were used as appropriate. Results: There was no significant difference between the four groups in terms of the mean values of plaque index, gingival index, BOP index, and stain index before the application of mouthwash. However, after mouthwash application, the mean values of indices were significantly different between the four groups. Aloe vera-green tea and chlorhexidine mouthwashes reduced plaque index, gingival index, and bleeding on probing index significantly and there was no significant difference between these two mouthwashes (P>0.05). The effect of matrica mouthwash on plaque index and gingival index was significantly lower than aloe vera-green tea and chlorhexidine (P<0.05). The mean reduction in BOP index was not significantly different between the aloe vera-green tea, chlorhexidine, and matrica groups. Regarding dental stain index, both herbal mouthwashes caused significantly lower dental stain in comparison with chlorhexidine (P<0.05). Conclusion: The results of the present study show that aloe vera-green tea mouthwash may be an effective mouthwash owing to its antiplaque and anti-inflammatory properties and may be an ideal substitute for chlorhexidine. Clinical Trial: The clinical trial code: IR.MUI.REC.1395.3.573
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Ravikumar, Chandini, Radhika Arjunkumar, and Gopinath Prakasam. "COMPARISON OF ANTIFUNGAL EFFECTS OF COMMERCIALLY AVAILABLE HERBAL MOUTHWASHES AND CHLORHEXIDINE AGAINST CANDIDA ALBICANS IN DIABETIC PATIENTS: AN IN VITRO STUDY." Asian Journal of Pharmaceutical and Clinical Research 9, no. 5 (September 1, 2016): 214. http://dx.doi.org/10.22159/ajpcr.2016.v9i5.13275.
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ABSTRACTObjective: Candida albicans is a part of the normal flora of the mouth in diabetes mellitus (DM) patients. Periodontitis is one of the main complicationsin diabetic patients. Mechanical and chemical plaque control are the most productive methods in preventing periodontal diseases in the oral cavity.The objective of this study is to compare the in vitro effect of herbal mouthwashes and chlorhexidine (CHX) against C. albicans.Methods: Saliva samples were obtained from diabetic patients reporting for treatment to Saveetha medical college. C. albicans was cultured from thesalivary sample. A yeast suspension was made by sub culturing the C. albicans. The mouthwashes used in the study are HiOra regular (0.2%), HiOrasensitive (0.5%), and clohex plus (CHX gluconate 0.02%) mouthwashes. The fungal suspension was spread on Sabouraud’s dextrose agar (SDA) plateswith a sterile swab. Subsequently, wells of 6 mm in diameter were made with a suitable distance using sterile cork borer on pre-inoculated agar platesand filled with 100 µl of each mouthwashes. From the zones of inhibition seen, antimicrobial activity was expressed in terms of average diameter ofthe zones of inhibition measured.Results: Using HiOra regular mouthwash, 13/18 (72%) wells were found to show zone of inhibition ≥20 mm. In HiOra sensitive mouthwash, only9/18 (50%) showed inhibition zone ≥20 mm. With effect of regular CHX mouthwash, none of the strains showed the zone of inhibition to be ≥20 mm.Most of the strains responded well with all the three mouthwashes.Conclusion: Among the 2 herbal mouthwashes, HiOra regular mouthwash was most effective in inhibiting the candidal growth when compared tothe HiOra sensitive. HiOra regular mouthwash still showed better inhibitory actions when compared to the regular CHX mouthwash and the candidalspecies showed increased sensitivity to it.Keywords: Candida albicans, Chlorhexidine mouthwash, Diabetes mellitus, Herbal mouthwashes, Zone of inhibition.
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Preethikaa Guruprasath, Ravishankar PL, Prem Blaisie Rajula M, Sunanda Rao K, Padmaja Vangipuram, and Visithiriyan G. "Evaluation of antimicrobial efficacy of Chlorhexidine, Listerine, and herbal mouthwashes in decontamination of toothbrushes-An invitro study." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (December 21, 2020): 7366–69. http://dx.doi.org/10.26452/ijrps.v11i4.4597.
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Toothbrushing and toothbrushes play an important role in oral hygiene. Disinfection, storage and changing of toothbrushes at regular intervals are essential. The aim of the present study is to evaluate the invitro efficacy of Chlorhexidine, Listerine ® and herbal mouthwash (Himalaya Oro-TTM) against microorganisms as toothbrush disinfectants. A total of 20 participants were recruited. Brand new identical toothbrushes were given to each participant and they were asked to brush their teeth twice daily. They were instructed to use tap water to rinse the used toothbrushes. The toothbrushes were collected after a week. The bristles of each toothbrush were cut and kept in separate vials containing transport media. Then, they were sent for microbiological evaluation. The number of colony-forming units were measured. The vials containing bristles were divided into four groups, each group containing 5 vials: Group I: Chlorhexidine mouthwash; Group II: Listerine mouthwash; Group III: Herbal mouthwash; Group IV: Distilled water. The bristles were immersed in test-tube containing respective mouthwashes for one hour. And, colony-forming units were measured. In all three test groups, there was a significant difference in the reduction of microbes after sanitization with mouthwashes. The highest reduction was seen in group I and the least reduction was group IV. Disinfection of toothbrush may prevent the occurrence of oral infections. Chlorhexidine mouthwash was found to be more effective than other mouthwashes as a disinfecting agent in reducing the microbial load.
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Ramamurthy, Jaiganesh, and Visha Mg. "COMPARISON OF EFFECT OF HIORA MOUTHWASH VERSUS CHLORHEXIDINE MOUTHWASH IN GINGIVITIS PATIENTS: A CLINICAL TRIAL." Asian Journal of Pharmaceutical and Clinical Research 11, no. 7 (July 7, 2018): 84. http://dx.doi.org/10.22159/ajpcr.2018.v11i7.24783.
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Objective: The aim and objective of this study was to evaluate the effect of Hiora mouthwash versus Chlorhexidine mouthwash for the treatment of gingivitis.Methods: The study population was comprised 30 gingivitis patients. The patients were randomly categorized into two groups of 15 patients in each group. Group A was given Chlorhexidine mouthwash and Group B was given Hiora mouthwash. Pre-operative measurements such as plaque index (PI), gingival index (GI), and probing depth (PD), and loss of attachment (LA) were measured. Oral prophylaxis followed by the prescription of mouthwash was done. The patients were recalled for a review after 15 days, and post-operative measurements were recorded.Results: From the statistical analysis in the experimental Group A and Group B, the mean values of PD, LA, GI, and PI were found to be significantly lower in the post-operative period than the pre-operative mean values. At the end of 15 days, almost comparable reduction in the amount of plaque and gingivitis was found in both Group A and Group B. Hence, the differences in efficacy of these two mouthwashes were non-significant.Conclusion: Hiora and Chlorhexidine mouthwashes were equally effective in the treatment of gingivitis.
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Sharma, Shivalal, C. Saimbi, Bandana Koirala, and Rakesh Shukla. "Effect of Various Mouthwashes on the Levels of Interleukin-2 and Interferon-γ in Chronic Gingivitis." Journal of Clinical Pediatric Dentistry 32, no. 2 (December 1, 2007): 111–14. http://dx.doi.org/10.17796/jcpd.32.2.u01p135561161476.
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The aim of this double blind study was to evaluate the effect of various mouthwashes: Chlorhexidine, Essential oil, Azadirachta indica (Neem) extract, and Povidone iodine on gingival tissue interleukin-2 (IL-2) and interferon-γ (IFN-γ) levels in patients with chronic gingivitis. A total of 80 patients (42 boys, 38 girls; mean age 16.0 ± 1.8 years) were included in this study. Patients were randomly assigned into four groups of 20 each: Group I- Azadirachta indica (Neem) extract, Group II - Essential oil, Group III - Povidone iodine, and Group IV - Chlorhexidine. They were instructed to use these mouthwashes for two weeks. Plaque and gingival indices scores, and IL-2 and IFN-γ levels in the gingival tissues were measured at baseline and after two weeks of mouthwash use. Results showed the reduction of plaque and gingival indices, and IL-2 and IFN-γ level with Chlorhexidine, Essential oil, and Povidone iodine, which were found to be statistically significant. Although Neem reduced the level of plaque and gingival indices, and IL-2 and IFN-γ to a certain level, it was not statistically significant. Therefore, Chlorhexidine, Essential oil, and Povidone iodine mouthwashes can be used as an adjunct to oral prophylaxis in reducing pro-inflammatory cytokines, IL-2 and IFN-γ in patients with chronic gingivitis.
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Sabarathinam, Jembulingam, Deepak Nallaswamy, Deepak Nallaswamy, Muralidharan Np, and Muralidharan Np. "COMPARISON OF HERBAL MOUTHWASH WITH COMMERCIALLY AVAILABLE 0.2% CHLORHEXIDINE AND 2% BETADINE MOUTHWASHES IN PATIENTS AFTER STAGE-1 IMPLANT SURGERY." Asian Journal of Pharmaceutical and Clinical Research 10, no. 12 (December 1, 2017): 56. http://dx.doi.org/10.22159/ajpcr.2017.v10i12.17786.
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Objective: The objective of the current study is to assess the antibacterial efficiency of an herbal mouthwash (clove and neem) against 0.2% chlorhexidine and 2% betadone mouthwash in patients who have undergone Stage-1 implant surgery.Methods: 30 patients undergoing implant surgery (Stage-1) were divided into 3 groups and were given 3 different mouthwashes. The patient was recalled after 15 days. Swab samples from the site of implant were taken after 15 days and cultured. The results were tabulated.Results: 0.2% chlorhexidine and 2% bernadine were found to have better antibacterial efficiency than herbal mouthwash (p>0.05).Conclusion: The herbal mouthwash consisting of neem and clove was not efficient in killing microbes immediately after Stage-1 implant surgery when compared to 0.2% chlorhexidine and 2% bernadine.
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Porwal, Surbhi, Aditi Mathur, Neema Shetty, Balaji Manohar, Barkha Makhijani, and Rohit Mundra. "Comparative Evaluation of the Effect of Chlorhexidine Gluconate, Raw Propolis and Hydrogen Peroxide on Dental Plaque and Gingival Inflammation." Journal of Nepalese Society of Periodontology and Oral Implantology 2, no. 1 (June 4, 2018): 14–19. http://dx.doi.org/10.3126/jnspoi.v2i1.23603.
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Background: Plaque is the soft deposit that forms the biofilm consisting of microorganisms adhering to the tooth surface and is proved beyond doubt to be the initiator of gingival and periodontal disease. Plaque control is the mainstay in periodontal disease.
Aim: To compare the effect of 0.2% chlorhexidine gluconate, raw propolis and 3% hydrogen peroxide mouthwash on dental plaque and gingival inflammation.
Materials and Methods: Thirty subjects in the age group of 20-40 years were enrolled in the study. Plaque index and Modified Gingival Index were recorded at baseline and oral prophylaxis was performed. Subjects were then randomly divided into three groups (n=10) and were asked to rinse with 10ml mouthwash twice daily for 15 days. Group I received 0.2% chlorhexidine gluconate mouth wash, Group II raw propolis diluted with distilled water (1:1), and Group III 3% hydrogen peroxide (1:1) mouthwash. Subjects were recalled on 7 day and 28 day for re-evaluation and recording plaque index and modified gingival index. Statistical analysis was done to evaluate the efficacy of all the three mouthwashes.
Results: The results showed that all the three mouthwashes were effective in reducing plaque and gingival inflammation. Chlorhexidine gluconate 0.2% showed to be the most effective in reduction of dental plaque. Propolis was observed to be the most effective in reducing gingival inflammation over a period of 28 days.
Conclusion: Propolis can be effectively used as a mouthwash without any potential side effects as an alternative to chlorhexidine mouthwash in reducing gingival inflammation.
Dissertations / Theses on the topic "Mouthwashes Chlorhexidine"
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Tam, Oi-wo Joyce. "Therapeutic effects of 0.12% chlorhexidine digluconate (Peridex®) in subjects with untreated gingivitis and presence of abundant calculus." Hong Kong : University of Hong Kong, 1995. http://sunzi.lib.hku.hk/hkuto/record.jsp?B16506911.
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Tam, Oi-wo Joyce, and 譚愛和. "Therapeutic effects of 0.12% chlorhexidine digluconate (Peridex®) in subjects with untreated gingivitis and presence of abundant calculus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B31953992.
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Cantarelli, Rômulo. "Soluções colutórias a base de clorexidina e óleos essenciais em formulações com e sem álcool : uma análise microbiológica e de percepção gustativa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/156584.
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Objetivo: O objetivo deste ensaio clínico duplo-cego randomizado e cruzado foi avaliar se a presença de álcool nas formulações de clorexidina e de óleos essenciais é capaz de influenciar significativamente a quantidade bacteriana em saliva, assim como verificar o impacto da presença do álcool sobre a percepção gustativa. Materiais e métodos: 20 indivíduos, 17 mulheres e 3 homens, com idades variando entre 18 a 38 anos, em bom estado de saúde, foram randomizados para bochechar de forma cruzada, as seguintes substâncias: gluconato de clorexidina com álcool, gluconato de clorexidina sem álcool, óleos essenciais com álcool e óleos essenciais sem álcool. Amostras de saliva estimulada foram colhidas antes e depois de cada bochecho e preparadas em meio de cultura viável para um amplo espectro de bactérias. Os resultados obtidos foram expressos em percentual de redução de UFC/ml de saliva. Uma escala visual analógica (EVA) foi usada para avaliar a percepção gustativa após cada bochecho Resultados: Não foram observadas diferenças significativas sobre o percentual de redução de bactérias salivares em relação às soluções de clorexidina (p = 0,55), ou de óleos essenciais (p = 0,85). Já a preferência gustativa em relação aos óleos essenciais foi fortemente afetada pela presença de álcool (p= 0,0001), o que não ocorreu na comparação entre as soluções de clorexidina (p=0,052). Conclusão: a presença do álcool não interfere na eficácia antimicrobiana de colutórios a base de clorexidina ou óleos essenciais. A presença de álcool nos óleos essências é avaliada de forma mais negativa em termos de percepção gustativ.Objective: The objective of this randomized, double-blind crossover clinical trial was to evaluate the presence of alcohol in chlorhexidine and essential oils formulations is able to significantly influence the bacterial quantity in saliva, as well as to check the impact of the presence of alcohol on taste perception. Methods: 20 subjects, 17 women and three men, aged between 18 and 38 years old, in good health, were randomized to rinse crosswise, the following substances: chlorhexidine gluconate with alcohol, chlorhexidine gluconate without alcohol, essential oils with alcohol and essential oils without alcohol. Stimulated saliva samples were collected before and after each rinse and prepared in the midst of viable culture for a broad spectrum of bacteria. The results were expressed as percent reduction of CFU/ml saliva. A visual analogue scale (VAS) was used to evaluate the taste perception after each rinse Results: No statistically significant differences were observed in bacterial reduction between the Chlorhexidine (p = 0.55), as well as for the essential oils (p = 0.85) formulations. However, the taste preference in relation to essential oils was strongly affected by the presence of alcohol (p = 0.0001), which did not occur in the comparison between the chlorhexidine solutions (p = 0.052). Conclusion: The presence of alcohol does not interfere in the antimicrobial efficacy of chlorhexidine or essential oils. The presence of alcohol in the essences oils is evaluated more negatively in terms of taste perception.
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Chong, Adeline Yang Li. "The effects of chlorhexidine containing toothpastes and tea tree oil containing mouthwashes on plaque and gingival inflammation : a thesis submitted in partial fulfilment for the degree of Masters [sic] of Dental Surgery (Periodontics)." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09DM/09dmc548.pdf.
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Francisconi, dos Rios Luciana Fávaro, Leslie Casas-Apayco, Marcela Pagani Calabria, Paulo Afonso Silveria Francisconi, Ana Flávia Sanches Borges, and Linda Wang. "Role of chlorhexidine in bond strength to artificially eroded dentin over time." Quintessence Publishing Group, 2015. http://hdl.handle.net/10757/607257.
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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.PURPOSE: To assess the long-term effect of a 2% aqueous chlorhexidine (CHX) solution on bond strength to artificially eroded dentin compared to sound dentin. MATERIALS AND METHODS: Flat mid-coronal dentin surfaces of extracted third molars (n = 28) were subjected only to grinding with a 600-grit SiC paper for 1 min (sound dentin S, n = 14) or additionally to erosive pH cycling with a cola-based soft-drink (eroded dentin E, n = 14). After acid etching, rinsing, and air drying, S and E were rehydrated with 1.5 μl of 2% CHX (S2%, n = 7; E2%, n = 7) or of distilled water (control SC, n = 7; EC, n = 7). Composite buildups were incrementally constructed with Filtek Z350 following Adper Single Bond 2 application. Specimens were sectioned into beams, which were subjected to microtensile testing immediately or after 6 or 12 months of aging. Fractured surfaces were observed under a digital microscope (50X magnification). Microtensile bond strength (μTBS) (MPa) was analyzed by three-way ANOVA and Tukey's tests (α = 0.05) and failure mode by the Kruskal-Wallis test (α = 0.05). RESULTS: Compared to sound dentin, eroded dentin was consistently related to lower μTBS. Immediately and after 12-month aging, the effect of CHX was insignificant, but it was significant after 6-month aging, when it conserved the bond strength to both eroded and sound dentin. The percentage of adhesive and mixed failures were equivalent, and significantly more frequent than cohesive failures, whether in dentin or in composite. CONCLUSION: The 2% CHX effect on bond strength conservation to both eroded and sound dentin was not found to be persistent.
Revisión por pares
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Abrahams, Gadija. "The antimicrobial efficacy of a carbohydrate derived fulvic acid as a pre-periodontal procedure mouth rinse." University of the Western Cape, 2017. http://hdl.handle.net/11394/6231.
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Magister Chirurgiae Dentium - MChD (Oral Medicine and Periodontics)The aim of this study was to assess whether a mouthwash containing carbohydrate derived fulvic acid, is effective in reducing the salivary microbial count pre-operatively. Endeavours have been made to reduce the risk of infection, bacteraemia and cross-contamination during dental procedures by the application of topical antimicrobial agents. To date chlorhexidine is the most widely evaluated and efficacious agent against oral biofilms but there have been reports of adverse effects ranging from contact dermatitis to severe anaphylactic shock. A new mouth rinse containing carbohydrate derived fulvic acid are reported to have broad spectrum antimicrobial activity against specific oral microbes and Candida albicans with no side effects.
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Relvas, Vânia Filipa da Silva Rocha. "Efeito do uso de antisséticos na flora oral." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5167.
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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA cavidade oral é constituída por mais de 600 espécies bacterianas, tornando-se esta um principal foco de estudo. A microbiota oral é extremamente complexa e única em cada indivíduo, sendo o género Streptococcus o mais prevalente. O microbioma oral é um dos mais completos do organismo humano, existindo várias comunidades bacterianas, que se encontram bem organizadas e estruturadas. Na verdade, a microbiota oral desempenha um papel fundamental na saúde do paciente, uma vez que contribui não só para o desenvolvimento do sistema imunitário, como também possui aspetos prejudiciais para os seres vivos. O desequilíbrio da placa bacteriana leva ao aparecimento de doenças orais, sendo a cárie e a doença periodontal as principais. De forma a minimizar a acumulação da placa bacteriana e as doenças associadas a estas, surgiram os métodos mecânicos de higienização oral. No entanto, estes apresentam algumas limitações, surgindo os antisséticos orais de forma a colmatá-las. Entre os antisséticos mais utilizados temos a clorexidina e o triclosan. A clorexidina é o gold-standard, possuindo um amplo espectro de ação, contra bactérias, vírus, fungos e leveduras. Esta substância é eficaz contra a redução de placa bacteriana, apresentando efeitos secundários, principalmente manchas ou coloração castanha nos dentes. O triclosan apresenta um espectro de ação contra fungos, vírus e bactérias, principalmente contra Gram-positivo, possuindo efeito antimicrobiano e um ligeiro efeito anti-inflamatório. Este antissético é preferencialmente utilizado em pastas dentífricas e elixires, principalmente porque possui menos interação com outros compostos. The oral cavity is constituted by more than 600 bacterial species, that’s why this cavity will be becoming a major focus of study. The oral microbiota is extremely complex, and unique to each person, and the most prevalent genus is Streptococcus. The oral microbiome is one of the most complete microbiomes in the human body, there are several bacterial communities, lying well organized and structured. In fact, the oral microflora plays a key role in the health of the patient, since it contributes to the development of the immune system, but also has aspects that are harmful to living things. The imbalance of bacterial plaque leads to the appearance of oral diseases, as caries and periodontal diseases are the principal ones. In order to minimize the buildup of the bacterial plaque and disease, the mechanical methods of oral hygiene appeared. However, they have some limitations, arising oral antiseptics in order to overcome the limitations of these methods. Among the most used antiseptic chlorhexidine and we triclosan. Chlorhexidine is the gold standard, having a broad spectrum of action, which includes bacteria, viruses, fungi and yeasts. This is effective against plaque reduction, with side effects, especially stains or brown staining on the teeth. Triclosan has a spectrum of activity against fungi, viruses and bacteria, especially against Gram-positive, having antimicrobial effect and having a slight anti-inflammatory effect. This antiseptic is preferably used in tooth pastes and elixirs, mainly because it has less interaction with other compounds.
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Fernandes, Inês Filipa Jesus. "Avaliação de péptidos no controlo antiplaca." Master's thesis, 2017. http://hdl.handle.net/10316/81976.
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Trabalho de Projeto do Mestrado Integrado em Medicina Dentária apresentado à Faculdade de MedicinaIntrodução: A cavidade oral caracteriza-se por ser um ambiente que suporta o desenvolvimento de microbiotas que aderem e se coagregam estrutural e tridimensionalmente formando o que se designa de biofilme. O controlo deste biofilme é crucial para a prevenção e tratamento da gengivite e doenças periodontais. A clorhexidina é o antimicrobiano que apresenta mais evidência como agente antiplaca. Neste contexto é importante reconhecer o conceito de eficácia comparativa dos vários agentes na ação do controlo da placa bacteriana e gengivite. Novas metas devem ser ultrapassadas com base na eficácia dos colutórios existentes, a fim de alcançar a diminuição da adesão da placa bacteriana.Objetivos: O presente estudo tem como objetivo a realização de uma revisão sistemática e de um projeto de investigação. A revisão sistemática pretende realizar uma avaliação do estado da arte sobre a eficácia comparativa da clorhexidina com outros antimicrobianos, enquanto agente preventivo da formação de placa bacteriana. O projeto de investigação pretende apresentar o desenho de uma metodologia experimental para avaliação de um novo produto composto por péptidos sintéticos, complementares a segmentos específicos das proteínas-alvo da saliva e potencialmente bloqueadores da formação de placa bacteriana.Materiais e Métodos: Foram utilizadas três base de dados eletrónicas: Biblioteca Nacional de Medicina, Washington, DC (MEDLINE-PubMed), Cochrane-CENTRAL e LILACS. A equação da pesquisa foi efetuada com os seguintes Mesh Terms “gingivitis”, “dental plaque”, “chlorhexidine” e “mouthwashes” interligando com os conectores booleanos “AND” e “OR”. A pesquisa foi feita segundo uma questão PICOT, obedecendo a critérios de inclusão e de exclusão. Relativamente ao projeto de investigação destacam-se a caracterização da saliva, os péptidos previamente sintetizados e a interação destes com culturas bacterianas de Streptococcus mutans.Resultados: Após pesquisa nas bases de dados obtiveram-se 385 artigos, dos quais 25 para leitura integral. Foram incluídas 14 publicações (5 revisões sistemáticas e 9 meta-análises). A clorhexidina é o antimicrobiano com melhor eficácia para os índices de placa e de inflamação gengival. Nos estudos anti-adesão dos péptidos, apesar das limitações inerentes, verificou-se uma aparente tendência em algumas concentrações para a inibição da criação de aglomerados bacterianos. Conclusões: A revisão sistemática concluiu que a clorhexidina continua a ser o gold standard para o controlo químico do biofilme. Os óleos essenciais apresentam menor eficácia que a CHX em estudos de curta duração, sendo mais indicados a longo prazo. Os trabalhos in vitro revelaram algumas limitações que pretendem ser ultrapassadas em estudos futuros.
Introduction: The oral cavity is characterized by an environment that supports the development of microbiotes that adhere and coagregate structurally and three-dimensionally forming what is called a biofilm. The control of this biofilm is crucial for the prevention and treatment of gingivitis and periodontal diseases. Chlorhexidine is the antimicrobial agent with the most evidence as an anti-plaque agent. In this context, it is important to recognize the concept of comparative effectiveness of several agents in bacterial plaque and gingivitis control. New targets should be provided based on the efficacy of mouthwashes in order to decrease plaque adhesion.Objectives: The aim of this work is to perform a systematic review and a research project. The systematic review intends to evaluate the state of the art on a comparative efficacy of chlorhexidine with other antimicrobial agents, as preventive agents for bacterial plaque formation. The research project intends the development of an experimental methodology to evaluate a new product composed of synthetic peptides, complementary to target salivary proteins and blocking plaque formation.Materials and Methods: Three electronic databases were used: National Library of Medicine, Washington, DC (MEDLINE-PubMed), Cochrane-CENTRAL and LILACS. The research equation was carried out with the following Mesh Terms "gingivitis", "dental plaque", "chlorhexidine" and "mouthwashes", connecting with the boolean connectors "AND" and "OR". The search was established according to a PICOT question, following inclusion and exclusion criteria. Regarding the research project, the characterization of saliva, previously synthesized peptides and the interaction of these with bacterial cultures of Streptococcus mutans should be highlighted.Results: After searching the databases, we obtained 385 articles, 25 of which were for integral reading. A total of 14 publications (5 systematic reviews and 9 meta-analyzes) were included. Chorhexidine is the most effective an timicrobial agent for plaque indices and gingival inflammation. The anti-adhesion peptide studies revealed an apparente tendency in some concentrations for an inhibition of bacterial aggregates.Conclusions: The systematic review concluded that chlorhexidine is still the gold standard for biofilm chemical control. Essential oils have less efficacy than chlorhexidine in short term studies, but improve in long term periods. In vitro evaluation revealed some limitations that are intended to be overcome in future studies.
Universidade de Coimbra - Custo do trabalho: 1000euros Local do financiamento: FMUC e Departamento de Química da UC
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Albeshir, Ebtehal. "The Impact of Mouthrinses on the Efficacy of Fluoride Dentifrices in Preventing Enamel and Dentin Erosion/ Abrasion." Thesis, 2018. http://hdl.handle.net/1805/17804.
Full textAbstract:
Objective: Toothbrushing with fluoride toothpaste followed by rinsing with mouthwash is a routine procedure to maintain good oral hygiene. It is unknown to what extent these rinses can modulate the effect of fluoride in its ability to prevent erosion/abrasion.The aim of this
in-vitro study was to investigate and compare the impact of chlorhexidine (CHX), essential oils (EO) and cetylpyridinium chloride (CPC) mouthrinses on erosive tooth wear protection afforded by conventional fluoride toothpastes.
Materials and Methods: The following experimental factors were considered: five rinses: CHX, EO, CPC, a fluoride rinse, and deionized water, two fluoride toothpastes: stannous fluoride (SnF2) or sodium fluoride (NaF) and two models: (erosion/ erosion+abrasion). Slabs of bovine enamel and dentin were prepared and embedded in resin blocks and generated 10 enamel and dentin testing groups (n = 8). UPVC tapes were placed on the sides of each slab leaving 1mm area exposed in the center. The blocks were subjected to a five-day cycling model. Then, the blocks were placed in a brushing machine and exposed to fluoride toothpaste slurry (one side was brushed and the other wasn’t). The blocks were then exposed to rinse treatments. Artificial saliva was used to remineralize the specimens after erosions and treatment challenges, and as storage media. After the fifth day of cycling, surface loss (in micrometers) was determined by profilometer. Data were analyzed using ANOVA (α = 0.05).
Results: There was no interaction among the three factors (type of toothpaste, mouthrinse and abrasion or not (dentin p = 0.0520, enamel p = 0.4720). There were no significant two-way interactions as SL was only affected by toothpaste and mouthrinse.
NaF caused less SL than SnF2 (4.60 vs. 5.83 μm; p < 0.0001) in dentin, whereas the opposite was found in enamel (5.20 vs. 3.56 μm; p < 0.0001). Toothbrushing abrasion caused comparatively more SL in enamel (6.53 vs. 2.23 μm; p < 0.0001) than in dentin (6.06 vs. 4.38 μm; p < 0.0001). None of the tested mouthrinses affected SL.
Conclusion: Commonly used mouthrinses containing antimicrobial agents or additional fluoride, do not impair the erosion/abrasion protection afforded by fluoride toothpastes. Tested SnF2 dentifrice offered greater protection against enamel surface loss and NaF dentifrices showed more protection for the dentin surface.
Clinical relevance: The understanding of the interaction between commonly used rinses and fluoride dentifrices will help dentists provide better recommendations to patients with erosive lesions.
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Rebelo, Nelson Daniel Sobral. "Avaliação clínica da utilização profilática de clorohexidina no controlo de complicações pós-operatórias na consulta de cirurgia oral da clínica dentária universitária da UCP." Master's thesis, 2014. http://hdl.handle.net/10400.14/15309.
Full textAbstract:
O acto cirúrgico oral é, por norma, uma intervenção que executada de forma planeada produz raras complicações tardias.
Os acidentes e complicações surgem por varias razões, nomeadamente falhas de diagnóstico e planeamento, técnica operatória deficiente, ausência de assépsia e um mau controlo pós-operatório. Torna-se então necessário controlar os sintomas pós-operatórios.
A clorohexidina é um anti-séptico que actua contra as bactérias da cavidade oral e é amplamente utilizada na medicina dentária. Bochechos orais com clorohexidina demonstraram uma redução da flora oral e uma redução na incidência de complicações pós-operatórias.
O objectivo deste estudo randomizado assenta na avaliação clínica da utilização profilática de clorohexidina no controlo das complicações pós operatórias na consulta de cirurgia oral da Clínica Universitária da Universidade Católica Portuguesa.
Foram constituídos dois grupos de estudo: GrupoI- ou grupo de controlo, em que não foi realizada profilaxia com clorohexidina; e o Grupo II constituído por indivíduos em que foi utilizada a profilaxia com clorohexidina, sendo posteriormente avaliadas na consulta de controlo várias complicações pós-cirúrgicos como hemorragias, hematomas, alveolites, edema, dor e trismo.
Os resultados obtidos revelaram que não existem diferenças estatisticamente significativas entre os grupos (p >0.05), no que concerne ao controlo das complicações pós-operatórias pelo que se pode inferir que o bochecho com clorohexidina parece não influenciar de forma marcada a incidência deste tipo de complicações.The oral surgical procedure is normally an intervention that correctly planned and executed produces rare postoperative complications. Accidents and complications arise for several reasons, including diagnosis and planning, incorrect surgical technique, poor aseptic care and postoperative control failures, becoming necessary to control postoperative symptoms. Chlorhexidine is an antiseptic against bacteria from the oral cavity and is widely used in dentistry. Oral rinses with chlorhexidine showed a reduction in oral flora and a reduction in the incidence of postoperative complications. The aim of this randomized study is to evaluate the prophylactic use of chlorhexidine in controlling postoperative complications in outpatient Oral Surgery at the University Clinic of the Catholic University of Portugal. Two study groups were designed: Group I - consisting of a control group in which no prophylaxis with chlorhexidine was performed, and Group II comprised of individuals that prophylaxis with chlorhexidine was used. In post-operative control visits were evaluated different parameters such as bleeding, bruising, alveolitis, edema, pain and trismus. The results revealed no statistically significant differences between groups (p> 0.05), in relation to the control of postoperative complications so we can say that rinsing with chlorhexidine seems not to influence the incidence of these type of complications
Conference papers on the topic "Mouthwashes Chlorhexidine"
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Kenyon, Chris, Vicky Cuylaerts, and Tania Crucitti. "P5.10 Inhibitory effect of chlorhexidine antiseptic mouthwash againstneisseria gonorrhoeae? an in-vitro study." In STI and HIV World Congress Abstracts, July 9–12 2017, Rio de Janeiro, Brazil. BMJ Publishing Group Ltd, 2017. http://dx.doi.org/10.1136/sextrans-2017-053264.626.
Full textReports on the topic "Mouthwashes Chlorhexidine"
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Chlorhexidine mouthwash is useful short-term for people with mild gum disease. National Institute for Health Research, July 2017. http://dx.doi.org/10.3310/signal-000442.
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