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1

Jirsová, Adéla. "Úloha laterality mozku v agonistickém chování jelena evropského II." Master's thesis, Česká zemědělská univerzita v Praze, 2016. http://www.nusl.cz/ntk/nusl-256635.

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The theoretical part of this diploma thesis deals with the role of brain laterality of red deer (Cervus elaphus) in agonistic behaviour. Therefore, the largest part of the review of published scientific outcome is devoted to the agonistic behaviour, namely it focuses on the fights between males during the autumn rut. Battles are strictly ritualized and males adhere to strict rules. The role of laterality in animals is being recently studied and the outcomes so far indicates that, particularly in agonistic interactions the laterality may play a significant role. Brain lateralization is simply a
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Šifra, Miroslav. "Aristoteles na magnetickej rezonancii: Čo vedy o mozgu vedia o scenáristike." Master's thesis, Akademie múzických umění v Praze.Filmová a televizní fakulta. Knihovna, 2015. http://www.nusl.cz/ntk/nusl-251451.

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Our stories are not taking place in the cinema, but in the mind of viewer - that's basic idea behind this thesis. Best tools for insight into the minds of people are coming from cognitive sciences, but their perspective is often ignored by screenwriters. How does the pattern-seeking brain works? Which psychological effects can influence the first act of screenplay? What is an anchoring? What screenwriter needs to know about selling home bakery? What is theory of mirror neurons and what it can teach us about an empathy? How much information is just too much? And how viewer's attention ope
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Janečková, Kamila. "Neuromarketing: Conceptualization of neuromarketing usage in marketing process." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-142289.

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Neuroscience is a new scientific discipline studying people's nervous system and brain, and among other things discovering how they decide and what motivates them. One of the branches of this study is neuromarketing which becomes to be increasingly used as a marketing research methodology which claims to reveal what people really think not only what they declare. There are still many question marks concerning this method, and, particularly in the Czech market where there is generally little notion about it, neither clients nor advertising agencies are sure whether and how to use it throughout
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Zíma, Stanislav. "vybrané důsledky informatizace ve společnosti." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-17404.

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The aim of the thesis is to describe selected consequences of informatization on the basis of three different views' critical synthesis. First view is an historical perspective focused on medialisation of information and its influence on shaping of man's thinking. On the background of technological progress are shown the milestones in changing of social reality. Another view is to describe the infromation society as a present phenomenon with its general characteristics. The last point of view is based on the hypothesis sof Global brain, which describes mankind as a network of nerve cells, conn
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Slánský, Vojtěch. "Operace lidského myšlení a jejich funkce při poznávání." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-193201.

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Subject of this work is human mind. In first section there are described important mechanisms, on which mind operates. Second section is devoted for description of unconscious mind and weaknesses it has. Some of the phenomenons are tested by an experiment and results are in the end of related chapter. The goal of this work is to create sumary of functioning of human mind, mostly of unconscious part and to test mistakes people are making in their judgement.
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6

Kněžík, Jan. "EEG biofeedback rozhraní lidského mozku a počítače." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2007. http://www.nusl.cz/ntk/nusl-412772.

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This master thesis dwells on EEGbiofeedback (also called Neurofeedback) interface of human brain and the computer and its concrete realization in Java programming language. This system is founded on the basis of the computer, which is accomplishing biological feedback (biofeedback) and the electroencephalography (EEG) by helping that state's scanning of user's brain is realized. By this way is possible to practise the human brain effectively to achieve better concentration, the elimination of sleeping and learning deficiency. Hereafter is the suggestion of direction control of computer mouse b
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Kuřátko, David. "Modelování mozku krysy." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377079.

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This master’s thesis deals with creation and modification of several numerical rat’s brain models which are subsequently used in electromagnetic software CST Studio Suite 2014. The first part of the thesis is focused to insertion of exciting source to the model which depends on the used approach. These sources produce signals on the surface of the rat’s brain model which are then analysed. The experimental part of the thesis dealt with three different procedures of cooking agar jelly, which were used for creation of five plate capacitors, which subsequently served for measure electric properti
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Trejbal, Pavel. "Zatíženost lidského myšlení v rozhodovacím procesu." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-15549.

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The focus of this thesis is mainly on the area of human decision making. During the decision process we are subjected to several influences, which bias our judgement. Therefore, we may be misguided towards wrong decisions. In addition, it is important that the display of distorted influence is regularly repeated with the same persons. Thus, we may assume that we are talking about a universal apparatus of the human mind. The aim of this thesis is also to identify the above-mentioned influences, and mainly to understand the nature of their origin. The knowledge resulting from the research could
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9

Motzek, Alexander [Verfasser]. "Indirect causes, dependencies and causality in Bayesian networks / Alexander Motzek." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2017. http://d-nb.info/1129726460/34.

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10

Čermák, Radim. "Vnímání a tvorba grafického designu v různých kulturách." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-17466.

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The modern world is more and more dependent on information. As grows its importance, so does its quantity. That is why the good communication, especially the visual one, is indispensable for the proper disclosure and addressing of potential recipients of information. Graphic design provides the form of visual communication. The interconnection of different cultures is linked with the quick pace of globalization - thus the communication with different cultures is important. Each culture is based on specific values that can vary and very often do to a great extent. These values are then reflecte
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11

Doyle, Rebecca. "Faces of the gods : Baal, Asherah and Molek and studies of the Hebrew Scriptures." Thesis, University of Sheffield, 1996. http://etheses.whiterose.ac.uk/5979/.

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The religion of ancient cultures has been captured in stone, clay, ink, gold and ivory. Huge wall reliefs down to tiny golden earrings or amulets have presented us with the faces of the gods. And which god is which, and what god did what, and who worshipped whom are questions that have fuelled the fires of many a scholar's imagination. As scholars have attempted the task of describing their chosen area, they have painted pictures for us. Unfortunately, in doing this they have often created portraits that are no more than pastiches. "The baal" of the Hebrew scriptures is described with the char
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12

Malý, Lukáš. "Ovládání invalidního vozíku pomocí klasifikace EEG signálu." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2015. http://www.nusl.cz/ntk/nusl-221361.

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Tato diplomová práce představuje koncept elektrického invalidního vozíku ovládaného lidskou myslí. Tento koncept je určen pro osoby, které elektrický invalidní vozík nemohou ovládat klasickými způsoby, jakým je například joystick. V práci jsou popsány čtyři hlavní komponenty konceptu: elektroencefalograf, brain-computer interface (rozhraní mozek-počítač), systém sdílené kontroly a samotný elektrický invalidní vozík. V textu je představena použitá metodologie a výsledky provedených experimentů. V závěru jsou nastíněna doporučení pro budoucí vývoj.
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Malínský, Miloš. "Pokročilé algoritmy fúze 3D medicínských dat pro specifické lékařské problémy." Doctoral thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-233603.

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Fúze obrazu je dnes jednou z nejběžnějších avšak stále velmi diskutovanou oblastí v lékařském zobrazování a hraje důležitou roli ve všech oblastech lékařské péče jako je diagnóza, léčba a chirurgie. V této dizertační práci jsou představeny tři projekty, které jsou velmi úzce spojeny s oblastí fúze medicínských dat. První projekt pojednává o 3D CT subtrakční angiografii dolních končetin. V práci je využito kombinace kontrastních a nekontrastních dat pro získání kompletního cévního stromu. Druhý projekt se zabývá fúzí DTI a T1 váhovaných MRI dat mozku. Cílem tohoto projektu je zkombinovat stuktu
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14

Mortera, Saul Levi Salomon Herman Prins. "Traktaat betreffende de waarheid van de wet van Mozes : eigenhandig geschreven in de Portugese taal te Amsterdam 1659-1660 /." Braga : Barbosa & Xavier, 1988. http://catalogue.bnf.fr/ark:/12148/cb36664695m.

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Proefschrift--Letteren--Katholieke Universiteit te Nijmegen, 1988.<br>Titre de couv. : Saul Levi Mortera en zijn "Traktaat betreffende de waarheid van de wet van Mozes" Introduction en néerlandais. Résumé en anglais.
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Hertog, Cok den. "Het zonderlinge karakter van de godsnaam : literaire, psychoanalytische en theologische aspecten van het roepingsverhaal van Mozes (Exodus 2.23-4.17) /." Zoetermeer : Uitg. Boekencentrum, 1996. http://catalogue.bnf.fr/ark:/12148/cb39928339c.

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16

Jezierska, Marta. "Organizacja zespołów żeńskich komórek płciowych i przebieg procesu oogenezy niesporczaka Hypsibius exemplaris Gąsiorek, Stec, Morek & Michalczyk 2018 (Eutardigrada, Parachela, Hypsibiidae)." Doctoral thesis, Katowice : Uniwersytet Śląski, 2018. http://hdl.handle.net/20.500.12128/7772.

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Tardigrades are poorly known group of microscopic Ecdysozoa. Together with Onychophora and Arthropoda, tardigrades belong to monophyletic group called Panarthropoda. Up till now tardigrades do not play any important role in practical or economical meaning. However, this small animals attract more and more scientist due to their special abilities. Thanks to stabilization of lipid membranes and nucleic acids they are able to withstand freezing, extreme dehydration, exposure on vacuum or ionizing radiation. Better understanding of their biology and how they are built is essential not only f
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17

Gröbner, Christina [Verfasser], Christian [Akademischer Betreuer] Mozet, Miloš [Akademischer Betreuer] Fischer, Andreas [Gutachter] Dietz, and Thomas [Gutachter] Neumuth. "Untersuchungen zur Anwendung eines mechatronischen Endoskopmanipulators für die endoskopische Nasennebenhöhlenchirurgie / Christina Gröbner ; Gutachter: Andreas Dietz, Thomas Neumuth ; Christian Mozet, Miloš Fischer." Leipzig : Universitätsbibliothek Leipzig, 2015. http://d-nb.info/1239657935/34.

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18

Shvetsov, Ivan [Verfasser], and M. [Akademischer Betreuer] Mozer. "Search for anomalous couplings in WW and WZ decays in the semileptonic channel with the CMS detector / Ivan Shvetsov ; Betreuer: M. Mozer." Karlsruhe : KIT-Bibliothek, 2017. http://d-nb.info/1132997607/34.

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19

Nissan, Ramina, and Bella Ombole. "Molek Diffstainer, Aerospray® Hematology Pro och manuell färgning enligt May-Grünwald Giemsa : En jämförande studie med hänseendet till färgningskvaliten, kostnadseffektivitet och tidsbesparing." Thesis, Hälsohögskolan, Högskolan i Jönköping, HHJ. Biomedicinsk plattform, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-31588.

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20

Mampuys, Alfred Frans Maria. "De Ik-splijting van de man Mozes en de inscheuring in zijn Ik een commentaar bij Freuds Mozeswerk, zijn Ik-splijtingstekst en de Wolfmancasus /." [S.l. : [Groningen] : s.n.] ; [University Library Groningen] [Host], 1997. http://irs.ub.rug.nl/ppn/158884930.

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21

Moek, Felix [Verfasser], and Guido [Akademischer Betreuer] Sauter. "Prävalenz und prognostische Relevanz der Amplifikation von HER2, CMYC und CCND1 in Tumoren von Tamoxifen-behandelten Brustkrebspatientinnen / Felix Moek. Betreuer: Guido Sauter." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2012. http://d-nb.info/1024772152/34.

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Stöhr, Matthäus [Verfasser], Andreas [Akademischer Betreuer] Dietz, Christian [Akademischer Betreuer] Mozet, Gunnar [Akademischer Betreuer] Wichmann, Ingo [Gutachter] Bechmann, and Florian [Gutachter] Lordick. "Die pharmakologische Beeinflussung des Hedgehog Signaltransduktionsweges in Kopf-Hals-Tumoren ex vivo / Matthäus Stöhr ; Gutachter: Ingo Bechmann, Florian Lordick ; Andreas Dietz, Christian Mozet, Gunnar Wichmann." Leipzig : Universitätsbibliothek Leipzig, 2015. http://d-nb.info/1239423349/34.

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Jileček, Jan. "Analýza a klasifikace dat ze snímače mozkové aktivity." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2019. http://www.nusl.cz/ntk/nusl-403817.

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This thesis aims to implement methods for recording EEG data obtained with the neural activity sensor OpenBCI Ultracortex IV headset. It also describes neurofeedback, methods of obtaining data from the motor cortex for further analysis and takes a look at the machine learning algorithms best suited for the presented problem. Multiple training and testing datasets are created, as well as a tool for recording the brain activity of a headset-wearing test subject, which is being visually presented with cognitive challenges on the screen in front of him. A neurofeedback demo app has been developed,
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Barbosa, Samuel Rodrigues. "DIVINDADES MLK E CULTO A MOLEK NOS QUADROS DA CRISE RELIGIOSA NO FINAL DA MONARQUIA DE JUDÁ (2 Reis 16,3; 17,17.31; 21,6; 23,10; KTU 1.100; 1.118; 1.161)." Universidade Metodista de São Paulo, 2004. http://tede.metodista.br/jspui/handle/tede/401.

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Made available in DSpace on 2016-08-03T12:20:15Z (GMT). No. of bitstreams: 1 Samuel Rodrigues.pdf: 122357 bytes, checksum: 30e0f08dd6f4f5c05f3d62e4a7850989 (MD5) Previous issue date: 2004-02-18<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The dissertation is addressed to a special and unsolved problem in the description of Israel´s religious development. In Old Testament texts about the human sacrifices, there are autonomous literary units regarding the mOlek cult. However, some scholars claim that the mOlek cult has not such character. The dissertation aspires to scruti
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Dutta, Baishali [Verfasser], Klaus [Gutachter] Mönig, Thomas [Gutachter] Lohse, and Matthias [Gutachter] Mozer. "Measurement of W+W− production cross section in proton-proton collisions at √s = 13 TeV with the ATLAS detector / Baishali Dutta ; Gutachter: Klaus Mönig, Thomas Lohse, Matthias Mozer." Berlin : Humboldt-Universität zu Berlin, 2018. http://d-nb.info/1185579036/34.

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Maja, Đurendić-Brenesel. "Distribucija opijatnih alkaloida u mozgu." Phd thesis, Univerzitet u Novom Sadu, Prirodno-matematički fakultet u Novom Sadu, 2008. http://dx.doi.org/10.2298/NS20080301DJURENDICBRENESEL.

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U ovoj doktorskoj disertaciji je uspe&scaron;no izvr&scaron;eno izolovanje&nbsp;opijatnih alkaloida iz humanih biolo&scaron;kih uzoraka (moždanog&nbsp;tkiva, krvi, urina i žuči) kao i biolo&scaron;kih uzoraka&nbsp;eksperimentalnih životinja (moždanog tkiva i krvi) primenom&nbsp;postupka čvrsto-tečne ekstrakcije (SPE-Solid Phase Extraction).&nbsp;Modifikovan je postupak za kvalitativnu i kvantitativnu GC-MS&nbsp;(Gas Chromatography-Mass Spectrometry) analizu biolo&scaron;kih&nbsp;uzoraka.&nbsp;Utvrđena je distribucija opijatnih alkaloida: morfina, kodeina,&nbsp;acetilkodeina, 6-acetilmorfina i
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Dejan, Kostić. "Морфологија акутних плакова мултипле склерозе на секвенци протонске густине при магнетнорезонантном снимању ендокранијума: значај у процени развоја болести". Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2017. http://www.cris.uns.ac.rs/record.jsf?recordId=104201&source=NDLTD&language=en.

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Увод: мултипла склероза (МС) је хронична, неуродегенеративна и аутоимуна болест у чијем дијагностиковању прегlед магнетном резонанцом (МР) има важну улогу.Утврђено је да МР параметри (повећање броја активних плакова и повећање укупном волумена Т2W лезија) дају само ограничене информације о природи и степену промена захваћеног ткива ЦНС, те не могу бити поуздани предиктори у процени развоја болести и клиничког исхода. Циљ: утврђивање применом PD секвенце, МР морфолошке параметре иницијално детектованих акутних плакова МС. Процена постојања разлике утврђених МР&nbsp; морфолошких параметара акутн
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Malečková, Dita. "Mozek a událost." Master's thesis, 2007. http://www.nusl.cz/ntk/nusl-289339.

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In my work I aspired to clarify the relationships between the vision and thinking. In the first part I was above all trying to show that the vision is not unchallenged, automatic process. Than I specify the intersection between vision and thinking and I went to the problem of motion and corporality (sensuality). In the second part I arrived to the theme of the space - with regard to the vision and thinking, as a "inscape", and I also outlined the probleme of metamorphosis of space in forms of toplological space, virtual space, or cyberspace. In the third part of my work I developed the theme o
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Fabian, Peter. "Úloha genů rodiny vent v časném embryonálním vývoji a ve vývoji mozku." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-348108.

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6 III ABSTRACT (ENGLISH) In chordates, the central nervous system (CNS) is derived from the dorsal part of gastrula. Induced dorsal part of the embryo - the neural plate - gives rise to the neural tube or primordial brain. The developing dorsal part of the embryo is shaped by BMP/Smad signaling from the ventral part. Using the basal chordate amphioxus, we show here the conserved evolutionary role BMP/Smad signaling in axial cell fate determination. Pharmalogical inhibition of BMP/Smad signaling induces dorsalization of Branchiostoma floridae (amphioxus) and Oryzias latipes (medaka) embryos and
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Pohanová, Petra. "Úloha m6A dráhy v regulaci kognitivních funkcí u potkanů v modelech Alzheimerovy choroby a kalorické restrikce." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405311.

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Reversible adenosine methylation (N6-methylation; m6A) at the RNA level was described in connection to the regulation of RNA fate. The N6-methyladenosine pathway is important for cognitive function and mechanisms related to memory, including the regulation of adult neurogenesis and synaptic plasticity. The objective of this study was to test the hypothesis that a decreased activity of the RNA-demethylase FTO is associated with improved cognitive function in rats. The RNA-demethylase FTO is a key regulator of the m6A pathway. In this study, we administered MO-I-500, a pharmacological inhibitor
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Rodný, Tomáš. "K psychologické problematice apalického syndromu u dětí." Master's thesis, 1997. http://www.nusl.cz/ntk/nusl-365810.

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Mackurová, Michaela. "Hodnocení účinnosti kvarterních reaktivatorů acetylcholinesterasy in vivo." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-382805.

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Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology & Toxicology Performed at: University of defence in Brno, Faculty of Military Health Sciences in Hradec Králové, Department of Toxicology and Military Pharmacology Student: Michaela Mackurová Leader of diploma thesis: PharmDr. Marie Vopršalová, CSc. Supervisor: kpt. PharmDr. Vendula Hepnarová, Ph.D. Title of diploma thesis: Evaluation of the efficacy of quarternary acetylcholinesterase reactivators in vivo NPL belongs to compounds of organic phosphorus and they are very common cause of poisoning as or
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Farár, Vladimír. "Adaptace centrálního nervového systému na chybění acetylcholinesterázy." Doctoral thesis, 2013. http://www.nusl.cz/ntk/nusl-327879.

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Acetylcholinesterase (AChE) effectively hydrolyzes acetylcholine (ACh). The inhibition of AChE is generally lethal and mice without AChE in all tissues (AChE KO) have severe impairments. In the brain, AChE is anchored in the plasma membrane by proline-rich membrane anchor (PRiMA), while in the muscles, AChE is anchored by collagen Q (ColQ) in the basal lamina. We report here that the PRiMA KO mice, in which AChE is essentially eliminated in the brain, show very little changes in behavior despite an excess of ACh in the brain and adaptation of ACh receptors comparable to those seen in AChE KO m
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Rydzyková, Tereza. "Vliv morfinu na neurogenezi a neurodegeneraci v mozku potkana." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-367807.

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Morfin is a clinically used analgesic drug but also an abusive drug. It has an impact on a wide range of CNS regions (nucleus accumbens, ventral tegmentum, hippocampus, etc.) and affects their functions, e.g. cognitive functions or anxiety. Although the results of so far published studies are often contradictory, the effects on cell death and proliferation in the CNS have been demonstrated. In this work, we focused on how chronic administration of morphine and subsequent withdrawal of this drug affects neurogenesis and neurodegeneration in the rat brain and how it affects some markers involved
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Tupý, Radek. "Komplexní předoperační zobrazování nádorů mozku." Doctoral thesis, 2018. http://www.nusl.cz/ntk/nusl-389253.

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Title Complex preoperative brain tumor imaging Abstract The differentiation of glioblastoma, metastases and brain lymphoma using modern diagnostic imaging methods has a major impact on the strategy of further diagnostic examinations and treatment. In a group of 67 patients with glioblastoma and 31 with cerebral metastasis, the ability to differentiate them according to the evaluation of perfusion parameters changes in peritumoral white matter by T1 dynamic post-contrast magnetic resonance imaging was verified, with the positive predictive value in glioblastoma detection up to 91%. In a group o
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Tabáková, Petra. "Úloha m6A dráhy v regulaci ontogenetického vývoje mozku potkana." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-405218.

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N6-methyladenosine (m6A) is the most ubiquitous post-transcriptional RNA modification and has an important role in determining the fate of mRNA transcripts. Among the key proteins of the m6A pathway are methyltransferases (METTL family enzymes), demethylases (FTO, ALKBH family enzymes), and m6A binding proteins (e.g., YTHDF family) which recognize RNA sequences depending on the amount and localization of m6A in target transcripts and subsequently influence the fate of mRNA transcripts. The role of methyltransferases and demethylases is to provide a dynamic balance of m6A levels and possibly to
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Ludínová, Kristýna. "Vymezení bolesti a paměťových stop strachu v prefrontální kůře." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-388118.

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Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Candidate: Kristýna Ludínova Supervisor: PharmDr. Jan Zitko, Ph.D. External supervisors: Dr. Manfred Oswald, Prof. Dr. Rohini Kuner Title of diploma thesis: Delineating Pain and Fear Engrams in the Prefrontal Cortex Pain is a complex process associated with activation of various brain centres. According to evidence of imaging studies in humans and rodents the medial prefrontal cortex (mPFC) ranks amongst the brain area consistently activated during painful perception. The
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Kelbich, Petr. "Principy neurochirurgické a neurointenzivistické likvorologie." Doctoral thesis, 2015. http://www.nusl.cz/ntk/nusl-333760.

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The principles of neurosurgical and neurointensive care liquorology We observed the development of the cerebrospinal fluid (CSF) patterns in 120 patients after bleeding in the CNS (central nervous system). We used our original cytological- energetic principle to investigate 1453 samples of the CSF from these patients. The principal aim of our investigation is the detection of immunocompetitive cells in the CSF and the specification of their activation via the coefficient of energy balance (KEB). Furthermore we evaluated the numbers of erythrocytes and leucocytes in the CSF and also the catalyt
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Pallag, Gergely. "Analýza markerů oxidativního stresu v mozku potkana: vliv maternální separace." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-393515.

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Adverse events that cause stress during the early stages of life may alter the normal development of the brain and neuroendocrine system and increase the vulnerability of the individual to various disorders. Chronic stress and subsequent releasing of stress mediators can lead to oxidative stress and cell damage. The first aim of this work was to determine selected oxidative stress markers in the cerebral cortex, hippocampus, and cerebellum after the exposure of rats to early life stress. To model the stressful situation, we used maternal separation of the offspring for three hours a day during
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Mašek, Jan. "Úloha transkripčního faktoru Tcf7l1 a signalizační dráhy Wnt/β-katenin během diferenciace hlavového ektodermu". Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-348110.

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Differentiation of the head ectoderm is crucial for the evolutionary diversification of vertebrates. Expression of the genes responsible for this process is orchestrated troughout complex gene regulatory networks that are induced and modulated by Wnt, FGF and BMP signaling pathways. In addition, Wnt/β-catenin signaling, in combination with expression of the Wnt antagonists from the rostral-most part of the head ectoderm, represent a key source of information for the regionalization of the tissue along the antero-posterior axis. This allows the differentiation of the anterior ectoderm that give
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KOVAŘÍKOVÁ, Jaroslava. "Alzheimerova demence v rodině - využití služeb denního, týdenního stacionáře." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-174707.

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The thesis focuses on care of clients with Alzheimer's, including the burden of family members and possible options of using services of a day care and a week care centre. The theoretical part of the thesis deals with Alzheimer's disease together with nursing care, health care system in the Czech Republic and possibility to use services of day care and week care centres. In the empirical part of the thesis the method of qualitative research was used. A non standardized interview was applied as a method of questioning. The results of the qualitative research clearly show that the care for clien
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Kyclerová, Hana. "Exprese a regulace Dexras1 ve strukturách mozku potkana za vývoje." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-367775.

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The Dexras1 gene was identified after induction by glucocorticoid dexamethasone in pituitary tumor cells. Dexras1 has also been found in other brain regions and in the peripheral organs but its expression is rhythmic only in the suprachiasmatic nuclei of the hypothalamus (SCN), where the mammalian main circadian pacemaker is located. Dexras1 expression was also affected by stress, amphetamine or prenatal alcohol exposure. Its role in cells has not yet been explained. Dexras1 GTPase activity has been determined to be dependent on the NMDA receptor stimulation. Dexras1 acts as an activator of G
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Svobodová, Libuše. "Levorukost a její akceptování v současném školství a rodinách." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-436605.

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TITLE: Left-handedness and its acceptance in contemporary education system and families AUTHOR: Libuše Svobodová DEPARTMENT: Department of Biology and Environmental Studies SUPERVISOR: doc. RNDr. Václav Vančata, CSc. ABSTRACT: The diploma thesis entitled Left-handedness and its acceptance in contemporary education system and families follows up and complements the bachelor thesis entitled The issue of left- handedness in the development of children and youth - history, present and perspectives. The first and second chapters of the theoretical part of the diploma thesis focus more deeply on the
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Kratochvílová, Simona. "Použití magnetické rezonance spektroskopie při studiu glukózového metabolismu." Doctoral thesis, 2018. http://www.nusl.cz/ntk/nusl-372610.

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Magnetic resonance spectroscopy (MRS) is a noninvasive technique that enables to follow metabolic processes in selected tissues in vivo. Recently the attention has been focused on metabolic mapping in target organs of insulin action to describe the pathophysiology of insulin resistance. The aim of our study was to present the practical application of ³¹P (phosphorus) MRS and ¹H (proton) MRS in metabolic studies of skeletal muscle in insulin resistant subjects and in subjects with impaired fasting glucose. The third study was aimed to evaluate the brain metabolism with ¹H MRS in healthy control
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Divín, Daniel. "Zánětem vyvolané změny v expresi kanabinoidních receptorů v ptačím mozku." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-435938.

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(EN) Research in interactions between the nervous and immune systems is focused mainly on mammals, while in other vertebrates, including birds, it remains neglected. Two types of cannabinoid receptors interconnect the nervous and immune systems: CB1, which is in mammals involved in regulation of neural processes, and CB2, which is in mammals involved in regulation of immune processes. However, little is presently known about the roles of these receptors in nervous and especially immune processes in birds. Therefore, in this work I focus on the expression of cannabinoid receptors in cognitively
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Řezáčová, Lenka. "Vliv kortikoliberinu a kortikosteronu na poškození hipokampu a jejich vztah ke kognici." Doctoral thesis, 2012. http://www.nusl.cz/ntk/nusl-310578.

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Dissertation "The influence of corticosterone and corticoliberin on damage of the hippocampus and their relation to cognition" deals with the cognitive, behavioral and histological changes in experimental rat strain long-evans that closer describe the consequences of long-term continuous application of corticoliberin and/or corticosterone. Testing of the behavioral changes was divided into two phases. The first one - within three or fourweeks respectively administration of these hormones, therefore until their early effects - and the second phase - after four weeks of completion of the first p
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Chott, Robert. "Ovlivní zvýšení tělesné teploty v průběhu epileptického statu u mláďat laboratorního potkana rozsah či charakter poškození hipokampu?" Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-306699.

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Febrile seizures are epileptic seizures, arising in connection with febrile conditions in children of prechool age. In adults with epilepsy is often present a history of febrile status epilepticus, seizure whose duration is longer than 20 minutes. To study the role of febrile status epilepticus (FSE) in the development of epilepsy and neuronal damage, it is necessary to have a relevant animal models. This work is focused on the morphological analysis of the new created model of febrile status epilepticus, using a combination of short-term hyperthermia and chemical induced status epilepticus at
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Flégrová, Eliška. "Mitochondriální respirace u chladově adaptovaných potkanů. Srovnání tkání." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-351497.

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Acclimation to cold or hardening is known for many decades through its beneficial effects on human health. In contrast, sudden exposure to cold, cold shock, is a great risk of cerebral and cardiac injury, especially in the elderly. There is very little published data on the cellular and molecular mechanisms induced by cold adaptation in heart and brain. The aim of this work was to describe and compare different properties heart, liver, brain and brown adipose tissue mitochondria of rats housed at 25 ± 1 řC and at mild cold (9 ± 1 řC, 5 weeks). The high-resolution oxygraphy, spectrophotometry a
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Žídek, Radim. "Wnt/β-kateninová signalizace ve vývoji mořského kroužkovce Platynereis dumerilii". Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-397475.

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Radim Žídek "Wnt/β-catenin signalling in the development of the marine annelid Platynereis dumerilii" (dissertation) Abstract: Wnt/β-catenin signalling is absolutely crucial for the early embryonic development of metazoan animals from the establishment of body axes, through the specification of germ layers and tissues to the development of organ systems. I used pharmacological manipulations of the Wnt/β-catenin pathway activity in the planktonic larvae of the marine polychaete annelid Platynereis dumerilii, the representative of the clade Spiralia, to investigate the role of Wnt/β- catenin sig
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Novotný, Jan. "Téma života u raného Bergsona." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-351933.

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This diploma thesis observes the topic of life in early Bergson. It is divided into three parts. The first chapter is concentrated on Essay on the Immediate Data of Consciousness. In this chapter we can become acquainted with the distinction between duration and space. This distinction is the basic of Bergson philosophy. We can also see the distinction between the deeper self and the surface self, which is based on the first distinction. The second chapter Matter and Memory shows how the foregoing distinctions are connected through the Bergson's theory of memory. In the last charter, named Cre
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