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Journal articles on the topic '#MP4042'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Hayer, Manvir, Anna Price, Shanat Baig, et al. "MP402TRENDS ON RIGHT VENTRICULAR FUNCTION ACROSS STAGES OF CKD IN A COHORT WITH MINIMAL CONVENTIONAL RISK FACTORS OF CARDIOVASCULAR DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii575—iii576. http://dx.doi.org/10.1093/ndt/gfx170.mp402.

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Dobre, Mirela, Kevin Kalisz, Prabhakar Rajiah, Minoo Alipour, Robert Gilkeson, and Thomas Hostetter. "MP404ASSOCIATION BETWEEN EXTENT OF MYOCARDIAL FIBROSIS ASSESSED BY NATIVE T1 MAPPING CARDIAC MAGNETIC RESONANCE AND BIOMARKERS AND THE LEVEL OF ESTIMATED GLOMERULAR FILTRATION RATE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii577. http://dx.doi.org/10.1093/ndt/gfx170.mp404.

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Assefa, Tewodros T., Temesgen F. Adametie, Abdu Y. Yimam, et al. "Evaluating Irrigation and Farming Systems with Solar MajiPump in Ethiopia." Agronomy 11, no. 1 (2020): 17. http://dx.doi.org/10.3390/agronomy11010017.

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Small-scale irrigation in Ethiopia is a key strategy to improve and sustain the food production system. Besides the use of surface water for irrigation, it is essential to unlock the groundwater potential. It is equally important to use soil management and water-saving systems to overcome the declining soil fertility and the temporal water scarcity in the region. In this study, the solar MajiPump was introduced to enable dry season crop production in Ethiopia using shallow groundwater sources. The capacity of the MajiPumps (MP400 and MP200) was tested for the discharge head and discharge using three types of solar panels (150 W and 200 W rigid, and 200 W flexible). Besides, drip irrigation and conservation agriculture (CA) farming systems were evaluated in terms of water productivity and crop yield in comparison to the farmers’ practice (overhead irrigation and tilled farming system). Results indicated that the maximum discharge head capacity of the MajiPumps was 18 m, 14 m, 10 m when using MP400 with 200 W rigid, MP400 with 200 W flexible, and MP200 with 150 W rigid solar panels, respectively. The corresponding MajiPump flow rates ranged from 7.8 L/min to 24.6 L/min, 3 L/min to 25 L/min, and 3.6 L/min to 22.2 L/min, respectively. Compared to farmer’s practice, water productivity was significantly improved under the CA farming and the drip irrigation systems for both irrigated vegetables (garlic, onion, cabbage, potato) and rainfed maize production. The water productivity of garlic, cabbage, potato, and maize was increased by 256%, 43%, 53%, and 9%, respectively, under CA as compared to conventional tillage (CT) even under overhead irrigation. Thus, farmers can obtain a significant water-saving benefit from CA regardless of water application systems. However, water and crop productivity could be further improved in the combined use of MajiPump with CA and drip irrigation (i.e., 38% and 33% water productivity and 43% and 36% crop productivity improvements were observed for potato and onion, respectively). Similarly, compared to CT, the use of CA significantly increased garlic, cabbage, potato, and maize yield by 170%, 42%, 43%, and 15%, respectively under the MajiPump water-lifting system. Overall, the solar-powered drip irrigation and CA farming system were found to be efficient to expand small-scale irrigation and improve productivity and livelihoods of smallholder farmers in Ethiopia.

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Nagai, Kei, Chie Saito, Koichi Asahi, et al. "MP400ANTIHYPERTENSIVE TREATMENT AND RISK OF CARDIO-VASCULAR MORTALITY IN PATIENTS WITH CHRONIC KIDNEY DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii575. http://dx.doi.org/10.1093/ndt/gfx170.mp400.

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5

Park, Cheol Ho, Chang-Yun Yoon, and Tae-Hyun Yoo. "MP401EXTRACELLULAR FLUID EXCESS IS SIGNIFICANTLY ASSOCIATED WITH CORONARY ARTERY CALCIFICATION IN PATIENTS WITH CHRONIC KIDNEY DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii575. http://dx.doi.org/10.1093/ndt/gfx170.mp401.

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6

Udayakumar, Arunkumar, David Ryan, Xia Li, Fahd Adeeb, Alexander Fraser, and Austin Stack. "MP403PREVALENCE OF HYPERURICAEMIA WITHIN THE IRISH HEALTH SYSTEM AND RELATIONSHIPS WITH CHRONIC KIDNEY DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii576—iii577. http://dx.doi.org/10.1093/ndt/gfx170.mp403.

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Fang, Jing, Wenge Li, Zhao Tan, and Min Tan. "MP405CHANGES IN THE PATTERN OF PRIMARY GLOMERULONEPHRITIS ONE SINGLE CENTER IN CHINA: 3,774 BIOPSIED CASES, NINE-YEAR RETORSPECTIVE STUDY." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii577. http://dx.doi.org/10.1093/ndt/gfx170.mp405.

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8

Sato, Yuji, Shouichi Fujimoto, Tsuneo Konta, et al. "MP406ANEMIA AS A RISK FACTOR FOR ALL-CAUSE MORTALITY; OBSCURE SYNERGIC EFFECT OF CHRONIC KIDNEY DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii577—iii578. http://dx.doi.org/10.1093/ndt/gfx170.mp406.

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9

Bayrakci, Nergiz, Ozlem Tasoglu, Nihal Ozkayar, et al. "MP407THE RELATIONSHIP BETWEEN PHYSICAL ACTIVITY STATUS AND SERUM IRISIN AND MYOSTATIN LEVELS İN PATIENTS WITH NON-DIALYSIS CHRONIC KIDNEY DISEASE." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii578. http://dx.doi.org/10.1093/ndt/gfx170.mp407.

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10

Taki, Fumika, Naoto Matsumoto, Taisuke Ishii, et al. "MP408LONG TERM OUTCOME OF CKD PATIENTS CARED BY NEPHROLOGIST - TIME TO EVENT RESEARCH." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii578. http://dx.doi.org/10.1093/ndt/gfx170.mp408.

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11

Tentori, Francesca, Charlotte Tu, Lindsay Zepel, et al. "MP409VARIATION IN RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITOR (RAASi) PRESCRIPTION INTERNATIONALLY AND ACROSS CKD STAGES." Nephrology Dialysis Transplantation 32, suppl_3 (2017): iii578. http://dx.doi.org/10.1093/ndt/gfx170.mp409.

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12

Innes, G., J. Andruchow, A. D. McRae, and E. Lang. "MP40: Do doctors cherry pick?" CJEM 20, S1 (2018): S55. http://dx.doi.org/10.1017/cem.2018.194.

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Introduction: Physician access to presenting complaint information may lead to cherry picking if some patients are seen as more attractive than others. Our objective was to determine whether chief complaint CC descriptors are associated with differing wait time to MD, hence whether physicians preferentially see patients with selected presenting complaints. Methods: We collated administrative data on all Calgary ED patients from 2016. Those in CTAS categories 1 and 5 were excluded, as well as fast track patients (because of single coverage). We described most common chief complaint (CC) categories and their median wait time to MD, adjusted for ED arrival site, patient sex, triage acuity, and need for admission. Results: We studied 128,812 subjects (54% CTAS2, 46% CTAS34) with 56,243 males and 72,569 females. Mean age was 50.6 years (sd=20), and most common CC categories (%) were abdominal pain (22%), chest pain (14.6%), musculoskeletal problems (7.2%), flank pain (5.2%), URI/Fever (4.7%), dyspnea (4.6%), headache (4.6%), and back pain (4.0%). Median TTMD was 84 min and admission rate in the study cohort was 30.4%. Multiple linear regression modeling showed that, in addition to CC category and ED arrival site, CTAS level, female sex, and need for admission changed TTMD by 18.6 min (per CTAS level), 6.6 min, -19.2 min respectively. Based on adjusted TTMD, the least attractive CC categories (adjusted median TTMD) were constipation (104 min), back pain (103), Depression/anxiety (103), abdominal pain (102), and dizziness/sensory disturbance (98); while the most attractive were trauma (44 min), allergic reaction (46), stroke symptoms (49), palpitations (61), and overdoses (66). Conclusion: There is a larger than expected difference in waiting times associated with specific chief complaint categories. This has implications for the way that patients are assigned to physicians or perhaps the way that chief complaint data is transmitted.

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Alhasyimi, Ananto Ali. "Antioxidant potency of mangosteen peel extract topical application in reversing reduced orthodontic brackets tensile strength after bleaching." Dental Journal (Majalah Kedokteran Gigi) 50, no. 4 (2017): 199. http://dx.doi.org/10.20473/j.djmkg.v50.i4.p199-204.

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Background: Nowadays, cosmetic dentistry has become an ever-increasing requirement with interest in it growing over time. Bleaching is one of the popular cosmetic treatments that has been proven to diminish the tensile bond strength (TBS) of orthodontic brackets attached to bleached teeth. Mangosteen peel (MP) extract contains antioxidants that may potentially reverse the reduction in TBS. Purpose: The purpose of this study was to evaluate the effect of MP extract on the post- bleaching TBS of brackets. Methods: The reported research constitutes an experimental in vitro study conducted on a total of 120 maxillary first premolar teeth randomly divided into six groups (n = 20) as follows: negative-control (NC: no bleaching), positive-control (PC: bleaching + no treatment), and the treatment groups (bleaching + 10% sodium ascorbate (SA), 10% (MP10), 20% (MP20) and 40% (MP40) MP extract gel). Post-treatment, the brackets were bonded using Transbond XT and TBS testing was performed using a Universal Testing Machine. The ARI was examined by means of a stereoscopic microscope, while enamel morphological changes were observed through a Scanning Electron Microscope. The TBS-generated data was analyzed by means of Anova and Tukey tests. For the Adhesive Remnant Index, a Kruskal-Wallis analysis test was performed. Results: There was a significant TBS difference (P = 0.001) between the various groups. The PC group showed the significantly highest TBS compared to the others (8.33 ± 3.92 MPa), whereas NC demonstrated the lowest (4.15 ± 2.27 Mpa). The TBS value of the MP40 group was considerably higher than other groups treated with antioxidants (7.87 ± 3.26 MPa). The failure of orthodontic brackets using MP extract mostly occurred at the adhesive-bracket interfaces. Conclusion: Topical application of 40% mangosteen peel (MP) extract as an antioxidant after bleaching was effective in reversing the reduced post-bleaching tensile bond strength (TBS) of orthodontic brackets.

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14

Lin, Chung-Shuen, Tso-Hsiao Chen, I.-Hsin Lin, An-Rong Lee, and Tz-Chong Chou. "The novel compound MP407 inhibits platelet aggregation through cyclic AMP-dependent processes." European Journal of Pharmacology 815 (November 2017): 324–31. http://dx.doi.org/10.1016/j.ejphar.2017.09.024.

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15

Tran, A., M. Redley, and K. de Wit. "MP40: Psychological distress in patients following pulmonary embolism diagnosis." CJEM 21, S1 (2019): S56—S57. http://dx.doi.org/10.1017/cem.2019.175.

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Introduction: Pulmonary embolism (PE) is a treatable condition, with a low mortality rate (of around 1% in those who are diagnosed with the condition). The risk of recurrent PE is well managed with long term anticoagulation. Past literature suggests that patients who are diagnosed with PE can go on to experience existential anxiety and symptoms suggestive of post-traumatic stress disorder (PTSD). This study aimed to evaluate the mental and emotional experiences of PE patients through the lens of PTSD, and the factors involved in psychological distress following a PE diagnosis. Methods: Semi-structured interviews were conducted with PE patients at the Juravinski Hospital thrombosis clinic in Hamilton, Ontario. Interview questions were based on DSM-5 criteria of PTSD and relevant existing literature. The transcripts were analyzed by two researchers based on an approach that considers both the content of patients’ accounts as well as the way that patients choose to interpret and deliver those accounts, to develop major themes associated with psychological distress. Results: A total of 37 patients, ranging from 28 to 85 years of age, were interviewed. The patients’ accounts suggested that the manner in which a PE diagnosis was delivered by an emergency physician was a significant factor in the degree to which they experienced psychological distress. For example, patients reported focusing on words suggesting that they were ‘a ticking time-bomb’ or that ‘a lot of people don't get through this,’ which introduced a degree of panic. A number of patients continued to focus on these words, months or years after their diagnosis. Some feared that they could have recurrent PE which could lead to death. Diagnoses that were delivered calmly with thorough explanations of why a patient experienced PE-related symptoms and how they will be treated, helped to minimize any subsequent anxiety. Patients initially misdiagnosed with an alternative condition in the ED also expressed feelings of anxiety and distress. The presence of physically and mentally distressing symptoms was also a factor which contributed to mental distress and anxiety regarding a PE recurrence. Conclusion: Caution should be taken in the delivery of PE diagnosis in the emergency department. Over-emphasis on the severity and life-threatening nature of PE should be avoided to reduce psychological distress.

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16

Zhao*, Hanson, Colby P. Souders, Kai Dallas, Paige Kuhlmann, Karyn Eilber, and Jennifer T. Anger. "MP40-01 ADVERSE EVENTS ASSOCIATED WITH SYNTHETIC MALE SLINGS." Journal of Urology 203 (April 2020): e585. http://dx.doi.org/10.1097/ju.0000000000000889.01.

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17

Dropkin*, Benjamin, Leah Chisholm, Jeremiah Dallmer, et al. "MP40-05 ARTIFICIAL URINARY SPHINCTER INSERTION IN THE ERA OF ANTIBIOTIC STEWARDSHIP." Journal of Urology 203 (April 2020): e587. http://dx.doi.org/10.1097/ju.0000000000000889.05.

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18

Rizvi, Ishtiakul, Ridwaan Sohawon*, Michelle Pipe, Thomas King, and Mohammed Belal. "MP40-20 MEDIUM TO LONG TERM SURGICAL RE-INTERVENTION RATE IN MALE SLING." Journal of Urology 203 (April 2020): e593-e594. http://dx.doi.org/10.1097/ju.0000000000000889.020.

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19

Loh-Doyle*, Jeffrey, Azadeh Nazemi, Akbar Ashrafi, et al. "MP40-13 ECTOPIC RESERVOIR PLACEMENT IN THE LATERAL RETROPERITONEUM DURING ARTIFICIAL URINARY SPHINCTER PLACEMENT." Journal of Urology 203 (April 2020): e591. http://dx.doi.org/10.1097/ju.0000000000000889.013.

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20

Tutolo*, Manuela, Giorgio Stabile, Giovanni Tasso, et al. "MP40-04 ANATOMICAL PROSTATE MPMRI FEATURES AND CONTINENCE RECOVERY AFTER ROBOT ASSISTED RADICAL PROSTATECTOMY." Journal of Urology 203 (April 2020): e586. http://dx.doi.org/10.1097/ju.0000000000000889.04.

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21

Boswell*, Timothy, Laureano Rangel, Brian Linder, and Daniel Elliott. "MP40-10 ARTIFICIAL URINARY SPHINCTER DEVICE SURVIVAL AND QUALITY OF LIFE OUTCOMES IN 1,154 PATIENTS." Journal of Urology 203 (April 2020): e589. http://dx.doi.org/10.1097/ju.0000000000000889.010.

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22

Niedźwiedź, Mateusz. "TYPE OF WEAR OF ALUMINIUM OXIDE LAYERS DEPENDING ON MANUFACTURING PARAMETERS." Tribologia 294, no. 6 (2021): 39–44. http://dx.doi.org/10.5604/01.3001.0014.8334.

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The article presents the type of wear of Al2O3 layers produced on the aluminium alloy EN AW-5251 depending on the production parameters. Oxide layers were produced by using DC anodizing in a ternary electrolyte at variable current density and electrolyte temperature. The layer scratch tests were carried out using a Micron- Gamma microhardness tester. The scratches of oxide layers were tested for the geometric structure of the surface using a Form TalySurf 2 50i contact profilograph. Contact thickness measurements were also made using a Dualscope MP40 device based on the eddy-current method. Using a scanning microscope (SEM), photos of the sample surfaces were taken to show and compare the surface morphology of the anodized layers in various parameters. Based on the research, it can be concluded that changes in the conditions of the production process of Al2O3 layers (electrolyte temperature and current density) have an impact on the type of tribological wear and changes in layer thickness. The largest thickness of the oxide layer (19.44 μm) was measured for Sample B produced at a current density of 3A/dm2 at an electrolyte temperature of 283 K, which was also characterized by the lowest value of the ratio of parameters f1 to f2 (0.584). The smallest thickness (5.32 μm) was measured for the Sample C anodized at 1 A/dm2 at 303 K, this sample had the largest ratio f1 to f2 (1.068) for the produced Al2O3 layers. Thanks to the parameters f1 and f2 and the calculation of their ratio, the wear process for Sample B was determined as scratching and microcutting, while for Sample C as grooving.

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Hikita*, Katsuya, Ryutaro Shimizu, Ryoma Nishikawa, et al. "MP40-06 BENIGN PROSTATIC HYPERPLASIA PATTERN AFFECTS THE EARLY POSTOPERATIVE CONTINENCE UNDERGOING ROBOT-ASSISTED RADICAL PROSTATECTOMY." Journal of Urology 203 (April 2020): e587. http://dx.doi.org/10.1097/ju.0000000000000889.06.

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24

Ward*, Ellen, Nicolas Ortiz, Mary West, Adam Baumgarten, and Allen Morey. "MP40-07 LONG-TERM OUTCOMES OF PERMANENT URETHRAL LIGATION FOR INCONTINENT MEN WITH END-STAGE URETHRA." Journal of Urology 203 (April 2020): e588. http://dx.doi.org/10.1097/ju.0000000000000889.07.

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"Sexual Function/Dysfunction: Evaluation I (MP40)." Journal of Urology 201, Supplement 4 (2019). http://dx.doi.org/10.1097/01.ju.0000558598.15976.fb.

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"Penile & Testicular Cancer I (MP40)." Journal of Urology 206, Supplement 3 (2021). http://dx.doi.org/10.1097/ju.0000000000002055.

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Dray, Elizabeth, Anne Cameron, Marybeth Hall, J. Quentin Clemens, and John Stoffel. "MP40-10 CAN URETHRAL BULKING AGENTS SALVAGE FAILED SLINGS?" Journal of Urology 197, no. 4S (2017). http://dx.doi.org/10.1016/j.juro.2017.02.1257.

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Tasian, Gregory, Angela Kalmus, and Susan Furth. "MP40-07 RECURRENCE OF SYMPTOMATIC KIDNEY STONES DIAGNOSED DURING CHILDHOOD." Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1189.

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29

Kovacevic, Larisa, Hong Lu, Joseph A. Caruso, and Yegappan Lakshmanan. "MP40-15 RENAL TUBULAR INJURY IN PEDIATRIC NEPHROLITHIASIS: PROTEOMIC EVIDENCE." Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1197.

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30

Dos Santos, Joana, Paul Bowlin, Fahad Alyami, and Walid Farhat. "MP40-18 OUTCOME ANALYSIS OF LOWER POLE STONES IN CHILDREN." Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1200.

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31

Priester, Alan, Fuad Elkhoury, Jacob Vandel, et al. "MP40-02 TARGETED PROSTATE BIOPSY: CANCER EXTENDS BEYOND THE ROI!" Journal of Urology 199, no. 4S (2018). http://dx.doi.org/10.1016/j.juro.2018.02.1269.

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Hawksworth*, Dorota, Angela Koomson, Emad Rajih, Kambiz Tajkarimi, and Arthur Burnett. "MP40-17 STANDARD STRETCHED LENGTH ASSESSMENT UNDERESTIMATES TRUE PENILE LENGTH." Journal of Urology 201, Supplement 4 (2019). http://dx.doi.org/10.1097/01.ju.0000556109.04975.7b.

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Kress, Taylor, Eric J. Belin De Chantemele, Jessica L. Faulkner, and Thiago Bruder do Nascimento. "Abstract MP40: Hiv Impairs Endothelial Function And Elevates Blood Pressure Via Tnfa Dependent Mechanisms In Male And Female Mice." Hypertension 76, Suppl_1 (2020). http://dx.doi.org/10.1161/hyp.76.suppl_1.mp40.

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HIV is a major health concern with over 37 million individuals worldwide living with HIV. The onset of combination antiretroviral therapy (cART) patients with HIV (PWH) live longer but exhibit accelerated development of cardiovascular disease. Clinical evidence indicates that 35% of PWH exhibit hypertension, however, the etiopathology is still ill-defined. We plan to take advantage of a transgenic mouse model (Tg26) that mimics patients with a repressed virus, to test the hypothesis that viral infection independent of cART induces endothelial dysfunction and hypertension via a TNF-α mediated mechanism. Vascular reactivity was analyzed via wire myography and blood pressure (BP) recorded via radio-telemetry. Results showed that viral infection impaired aorta endothelium-dependent relaxation as reflected by a decrease in acetylcholine-mediated relaxation in both Tg26 mice (P<0.05) which was ameliorated with the NOX 1/4 inhibitor GKT 137831. Smooth muscle cell-dependent relaxation (SNP) and contractility to phenylephrine and KCl remained intact in Tg26 mice. Viral infection increased systolic, diastolic, and mean arterial pressure (MAP: male: WT=112.3±1.3 vs Tg26=121.9±4.0 mmHg/ female: WT=110.6±3.01/ Tg26=120.3±6.9 mmHg) and elevated heart rate (HR) in both sexes (p<0.05). We used atropine, propranolol, and hexamethonium in WT and Tg26 mice to investigate the contribution of the autonomic nervous system to hypertension. HR responses to both atropine (Female: +5.07±2.8% vs. male +4.3±5.4% of baseline) and propranolol (Female: 19.9±6.1% vs. male 12.0±4.3%) revealed no significance or sex differences in WT mice and no effects of viral infection on autonomic control of heart rate in Tg26 mice. BP responses to hexamethonium revealed no effect of sex or viral infection, supporting a limited contribution of the autonomic nervous system to hypertension in Tg26 mice. However, we found that TNFα inhibition with etanercept reduced mean arterial pressure in Tg26 mice to the level of the WT mice (WT=112.3±1.3, Treated=110.1±0.185) and improved endothelial function. These data indicate that HIV infection contributes to cardiovascular disease via inducing endothelial dysfunction and hypertension via NOX and TNFα-dependent mechanisms respectively.

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Yuan, Mengjie, Richard T. Pickering, Martha R. Singer, Margaret L. Bradlee, and Lynn L. Moore. "Abstract MP40: Higher Intakes of Animal Protein Helps Maintain Functional Status and Grip Strength in Older Adults in the Framingham Offspring Study." Circulation 139, Suppl_1 (2019). http://dx.doi.org/10.1161/circ.139.suppl_1.mp40.

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Li, Changwei, Ruiyuan Zhang, Luqi Shen, and Sangzhu Laba. "Abstract MP40: U-shaped Association Of Altitude With Prevalence Of Hypertension Among Tibetan Residents." Circulation 141, Suppl_1 (2020). http://dx.doi.org/10.1161/circ.141.suppl_1.mp40.

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Background: Tibet has a disproportionately higher prevalence of hypertension, compared to other regions of China. This may be related to long-term exposure to the high altitude. The aim of our study is to evaluate associations of altitudes with prevalence of hypertension among residents aged 15 years and older in Tibet, China. Method: A total of 11,407 Tibet residents in the 5 th National Health Services Survey (NHSS) in 2013-2015 were included in this study. Physician diagnosed hypertension was determined based on self-report. County level altitude was identified and assigned to all residents in a county. Association between altitude and hypertension prevalence was assessed by two logistic regression models: model 1 adjusted for age and gender, and model 2 additionally adjusted for marital status, education, smoking, drinking, exercise, distance to a medical institute, area of residency, and body mass index (BMI). Non-linear relationship between altitude and prevalence of hypertension was explored by restricted cubic spline analyses. Sensitivity analysis were performed by restricting residents in rural and/or nomadic areas. Result: The prevalence of self-reported hypertension is 15.7%, the medication adherence rate is 14%, and the control rate is 10.3%. Compared to residents without physician diagnosed hypertension, those with hypertension were closer to a hospital, older, having lower education level, and less likely to be a smoker or live in an urban area. Altitude showed a U shape relationship with the prevalence of hypertension with a turning point at around 3,800 meters. For residents living more than 3,800 meters above sea level, a 1,000 meters increase in altitude was associated with 2.05 (95% confidence interval: 1.62-2.61) times higher odds of having physician diagnosed hypertension, after adjusting for age and gender. When further controlling for all covariates, the OR dropped to 1.87 (1.46-2.41) but still significant. For residents living below the altitude of 3,800 meters, 1000 meters’ increase was associated 0.55 (95% CI: 0.33-0.92) less likelihood of having physician diagnosed hypertension. Conclusion: The burden of self-reported hypertension was high among Tibet residents. Altitude was in a U-shaped association with the prevalence of hypertension with a turning point at around 3,800 meters.

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Guasch, Marta, Geng Zong, Walter Willett, et al. "Abstract MP40: Associations of Monounsaturated Fatty Acids From Plant and Animal Sources With Total and Cardiovascular Mortality Risk." Circulation 137, suppl_1 (2018). http://dx.doi.org/10.1161/circ.137.suppl_1.mp40.

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Background: Studies regarding monounsaturated fatty acid(MUFA) intake and mortality have reported inconsistent findings.Dietary MUFAs can come from both plant and animal sources with divergent nutrient components that potentially obscure the associations for total MUFAs. Hypothesis: We hypothesized that MUFA from plant sources(MUFA-P) is more likely to be inversely associated with mortality than MUFA from animal sources (MUFA-A).Replacing saturated fatty acids(SFA), trans fat,or refined carbohydrates by MUFA-P would be associated with a lower risk. Methods: We included 63,412 women from the Nurses’ Health Study(1990-2012) and 29,966 men from Health Professionals Follow-up Study(1990-2010). MUFA-Ps and MUFA-As were calculated based on validated food frequency questionnaires collected every 4-y and food composition databases that capture changes in composition over time. Results: During 1,896,864 person-years of follow-up, 20,672 total and 4,588 cardiovascular deaths occurred.MUFA-P was inversely associated with total mortality after adjusting for potential confounders [HR:0.84(95%CI:0.79,0.89) P <0.01], whereas MUFA-A was associated with higher risk [1.21(1.07,1.37), P <0.01].Isocalorically replacing SFAs (5% of total energy), refined carbohydrates (5% energy),or trans fat (2% energy) with MUFA-Ps was associated with 15%, 14%, and 10% lower risk of total mortality, respectively. Mortality risk was 24% lower when MUFA-Ps were modelled to replace MUFA-As(5% energy),and 20% lower when the sum of SFAs and MUFA-As(5% energy) was replaced.Similar results were observed for cardiovascular mortality for the same substitutions:HR(95%CI) were 0.74 (0.64, 0.85; P <0.01) for replacing MUFA-A and 0.83 (0.76, 0.92; P <0.01) for replacing SFA+MUFA-A. Conclusions: Higher MUFA-P intake was associated with lower total mortality and MUFA-A was associated with higher mortality.Significantly lower mortality was observed when SFAs, trans fats,or refined carbohydrates were replaced by MUFA-P, but not MUFA-A.

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Williams, Janice E., Willem J. Kop, Anna Kucharska-Newton, David J. Couper, and Thomas Mosley. "Abstract MP40: Vital Exhaustion as a Predictor of Recurrent Cardiac Events in Patients with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation 129, suppl_1 (2014). http://dx.doi.org/10.1161/circ.129.suppl_1.mp40.

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Several studies have demonstrated a positive relationship between vital exhaustion and incident coronary heart disease (CHD), but the association of exhaustion with recurrent cardiac events has not been established in large, epidemiologic studies. Vital exhaustion is considered the end-stage of prolonged psychological distress and is characterized by excessive fatigue, increased irritability, and a sense of demoralization. We assessed the hypothesis that vital exhaustion predicts recurrent cardiac events (myocardial infarction and CHD-related mortality) among middle-aged men and women with documented CHD. Participants were 589 black or white men and women (mean age = 59.8; range = 47 - 69 years) with a history of CHD at the 1990-1992 clinical examination of the ARIC Study. Vital exhaustion was measured at the same ARIC examination using the 21-item Maastricht Questionnaire, and scores were categorized into quartiles. Recurrent cardiac events were monitored in short term (0-5 years), mid- term (6-13 years), and long-term (14-19 years) follow-up. Cox proportional hazards regression models were adjusted for age, sex, race-center, educational level, body mass index, plasma LDL-and HDL-cholesterol levels, hypertension status, and pack-years of cigarette smoking. During short term follow-up, the risk for recurrent cardiac events among participants in the highest quartile of vital exhaustion was twice that of participants in the remainder of the sample (HR = 2.08; 95% C.I: 1.24 to 3.48). The risk was less strong but remained statistically significant in mid-term (HR = 1.77; 95% C.I: 1.26 to 2.48) and long-term (HR = 1.54; 95% C.I: 1.12 to 2.11) follow-up. In conclusion, vital exhaustion is positively associated with short-term and long-term risks for recurrent cardiac events among middle-aged men and women with established coronary heart disease, independent of the traditional biomedical risk factors.

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Arenaz, Cristina M., Gaurav Baranwal, Bethany L. Goodlett, Joseph M. Rutkowski, Robert C. Alaniz, and Brett M. Mitchell. "Abstract MP40: Microbiome-associated Metabolites Are Altered In Mouse Models Of Hypertension." Hypertension 78, Suppl_1 (2021). http://dx.doi.org/10.1161/hyp.78.suppl_1.mp40.

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Recent studies suggest that the microbiome plays a key role in hypertension and associated inflammation. Microbiota produce metabolites that may lead to activated pro-inflammatory immune cells and contribute to hypertension; however, the altered metabolites in multiple models of hypertension is currently unknown. We hypothesized that there are significant differences in metabolomic profiles between normotensive and hypertensive mice. We utilized two mouse models of hypertension: L-arginine methyl ester hydrochloride (L-NAME)/high salt diet induced hypertension (LSHTN) and angiotensin II induced hypertension (A2HTN). Serum and fecal samples were collected at the end of the treatment period. Ultra-high performance liquid chromatography and tandem mass spectrometry were performed to identify the biochemical composition of each sample. Random Forest Analysis was performed to classify each sample based on similarities and differences in metabolite composition. These procedures were performed by Metabolon, Inc. A total of 1,066 and 1,028 biochemicals were measured in serum and feces, respectively. There were 263 biochemicals in LSHTN serum and 122 biochemicals in A2HTN serum that were statistically different from controls (p≤0.05). There were 298 biochemicals in LSHTN feces and 64 biochemicals in A2HTN feces that were statistically different from controls (p≤0.05). Five biochemical metabolite groups were shown to have significant differences between hypertensive groups and controls: aromatic amino acids, bile acids and sterols, benzoates, fatty acids, and diacylglycerols. Tryptophan metabolites were significantly reduced in the serum of LSHTN mice but not in the serum of A2HTN mice. Serum tyrosine and benzoate metabolites showed varied differences between the two hypertensive groups. Serum fatty acid beta oxidation metabolites were significantly reduced in both hypertensive models but were significantly increased in the feces of mice with LSHTN. In conclusion, this study provided significant analysis of metabolite changes in two hypertension mouse models. Further investigation of the roles these metabolites play in hypertension may lead to targeted therapeutic interventions.

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Acosta, Julian N., Natalia Szejko, Cameron Both, et al. "Abstract MP40: Klotho -vS Heterozygosity is Associated With Lower Risk of Lobar Intracerebral Hemorrhage." Stroke 52, Suppl_1 (2021). http://dx.doi.org/10.1161/str.52.suppl_1.mp40.

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Introduction: Klotho is a transmembrane protein highly expressed in the kidneys and choroid plexus. Klotho modulates insulin sensitivity and suppresses oxidative stress. Two missense variants in the Klotho gene ( KL ) form the functional haplotype KL-VS . Heterozygosity for KL-VS ( KL-VS-Het+ ) increases serum levels of Klotho and attenuates the excess risk of Alzheimer’s Disease conferred by APOE epsilon 4. We tested the hypothesis that KL-VS-Het+ lowers the risk of spontaneous intracerebral hemorrhage (ICH) and the excess in this risk conferred by the APOE epsilon variants. Methods: We conducted a genetic association study that combined publicly available data from 3 case-control studies of ICH in Europeans. We identified the two genetic variants that define KL-VS (rs9536314 and rs9527025) and the two genetic variants that define the APOE epsilon alleles (rs429358 and rs7412). We tested for association between KL-VS-Het+ and ICH risk via study-specific logistic regression followed by fixed-effects, inverse-variance weighted meta-analysis using I 2 to quantify heterogeneity. Given the known biological differences between lobar and non-lobar ICH, we conducted stratified analyses based on location. Additionally, we evaluated the role of KL-VS-Het+ in carriers of APOE epsilon 2 and 4 variants. Results: A total of 1066 ICH cases (464 lobar and 602 non-lobar) and 1073 controls were included in the study (mean age 69 [SD 14], female sex 919 [47%]). KL-VS-Het+, present in 554 (26%) participants, was associated with a lower risk of ICH (OR 0.81, 95%CI 0.67-0.99; p=0.04) without heterogeneity across studies (I 2 =0%). Stratified analyses indicated that KL-VS-Het+ was associated with a lower risk of lobar ICH (OR 0.68, 95%CI 0.52-0.88; p=0.004) but not of non-lobar ICH (OR 0.92, 95%CI 0.73-1.16; p=0.48). In secondary analyses, KL-VS-Het+ was associated with a lower risk of ICH in carriers of APOE epsilon 2 (OR 0.52, 95%CI 0.28-0.96; p=0.037; I 2 =0%) but not epsilon 4 (OR 0.82, 95%CI 0.5-1.33; p=0.42). Conclusion: KL-VS -Het+ is associated with a lower risk of ICH. This protective association was stronger in lobar hemorrhages and in carriers of APOE epsilon 2. Further research should evaluate these associations in non-Europeans and identify the mediating molecular pathways.

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Illiano, Ester, Raffaele Balsamo, Martina Milanesi, et al. "MP40-19 MIRABEGRON IN WOMEN WITH OAB: A REAL SETTING STUDY." Journal of Urology 197, no. 4S (2017). http://dx.doi.org/10.1016/j.juro.2017.02.1266.

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Andrews*, Jack, Kevin Hebert, Mathew Ziegelmann, et al. "MP40-08 DO PATIENTS WHO REPORT PREMATURE EJACULATION ACTUALLY EJACULATE QUICKER?" Journal of Urology 201, Supplement 4 (2019). http://dx.doi.org/10.1097/01.ju.0000556100.89727.93.

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Vedovo*, Francesca, Lisa Di Blas, Chiara Perin, et al. "MP40-14 ITALIAN RESIDENTS IN UROLOGY SEXUAL HEALTH: A MULTICENTRIC STUDY." Journal of Urology 201, Supplement 4 (2019). http://dx.doi.org/10.1097/01.ju.0000556106.20222.6f.

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Kim, Myung Ki, Jae Hyung You, and Yu Seob Shin. "MP40-04 THE RELATIONSHIP OF FEMALE URETHRAL LENGTH WITH STRESS URINARY INCONTINENCE." Journal of Urology 197, no. 4S (2017). http://dx.doi.org/10.1016/j.juro.2017.02.1251.

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Wimberly, Jennifer, Shawn Okpara, and Philippe Zimmern. "MP40-20 DO SURGEONS WISH TO KNOW ABOUT THEIR LONG-TERM COMPLICATIONS?" Journal of Urology 197, no. 4S (2017). http://dx.doi.org/10.1016/j.juro.2017.02.1267.

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Syed, Jamil, Christopher Chew, Anup Kumar, et al. "MP40-05 EVALUATION OF OUTCOMES OF SALVAGE ROBOTIC PROSTATECTOMY: SINGLE SURGEON EXPERIENCE." Journal of Urology 195, no. 4S (2016). http://dx.doi.org/10.1016/j.juro.2016.02.151.

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Dangle, Pankaj, Elina Mukherjee, and Sunder Sims-Lucas. "MP40-04 EMBRYONIC TESTIS CONTAINS VASCULAR ENDOTHELIAL PRECURSOR CELLS- A NEW INSIGHT." Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1186.

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Riddell, Jonathan, Gerald Mingin, Benjamin King, Devin Halleran, Nazih Khater, and Hassan Razvi. "MP40-14 ACHIEVING A STONE-FREE PEDIATRIC PERCUTANEOUS NEPHROLITHOTRIPSY: DOES AGE MATTER?" Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1196.

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Tuncer, Murat, Cahit Sahin, Ozgur Yazici, et al. "MP40-16 DOES EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY CAUSE HEARING IMPAIRMENT IN CHILDREN?" Journal of Urology 193, no. 4S (2015). http://dx.doi.org/10.1016/j.juro.2015.02.1198.

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Durso, Timothy, Robert Blackwell, Adam Van Huis, et al. "MP40-12 ENUCLEO-RESECTION MAXIMALLY PRESERVES RENAL PARENCHYMAL VOLUME IN PARTIAL NEPHRECTOMY." Journal of Urology 191, no. 4S (2014). http://dx.doi.org/10.1016/j.juro.2014.02.1347.

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Kwong*, Jethro C. C., Yonah Krakowsky, and Ethan Grober. "MP40-05 DIAGNOSIS AND MANAGEMENT OF TESTOSTERONE DEFICIENCY - COMPARISON OF CURRENT GUIDELINES." Journal of Urology 201, Supplement 4 (2019). http://dx.doi.org/10.1097/01.ju.0000556097.43986.de.

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