Academic literature on the topic 'MPCV'

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Journal articles on the topic "MPCV"

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Arenson, E. B., J. Bank, M. Pierick, C. Greenwald, J. McVicker, J. P. Elliott, J. D. Day, and T. M. Fullagar. "Use of modified PCV chemotherapy as principal therapy for adults with incompletely resected or recurrent low-grade glioma: A retrospective review." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 1571. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.1571.

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1571 Background: In order to assess outcomes of patients treated with chemotherapy versus a more standard approach of radiotherapy (RT), we reviewed 48 patients with newly diagnosed, partially resected or recurrent low-grade glioma (LGG) treated between 1996 and the present. Methods: Patients were divisible into three groups: those treated with chemotherapy ± RT before (Group A, 28 patients) or after (Group B, 13 patients) radiographic progression, and those with recurrences after treatment with RT (Group C, 7 patients). Diagnoses included astrocytoma (23%), oligodendroglioma (48%) and mixed glioma (29%). 39 patients were treated with chemotherapy alone and 9 received post-chemotherapy RT. Chemotherapy consisted of PCV in one case; all other patients received modified PCV (MPCV) which variably included addition of carboplatin (200–360 mg/m2) and etoposide (150 mg/m2) and substitution of temozolomide (150 mg/m2 × 5 doses) for procarbazine. The intent was to treat monthly for one year. Results: Patients received a mean of 10 courses of MPCV; 481 cycles were given. There were no deaths or admissions during chemotherapy. Grade III/IV toxicities occurred in 108 cycles (25 patients), 107 hem. and 1 GI. Late events included 1 case of MDS and 1 AML. There were no cases of disease progression during chemotherapy. Two patients stopped MPCV early, one because of worsening seizures (2 cycles) and one by personal preference (1 cycle); both died of disease. With median follow-up of 46 months (range 4–120) from initiation of chemotherapy, overall survival and progression-free survival were 89% and 79% for Group A, 91% and 83% for Group B, and 100% and 86% for Group C. Of 7 patients (15%) who recurred after completing chemotherapy, 2 have died; both had received post-chemotherapy RT and had clinical features of GBM. Four patients are either lost to follow-up (2) or alive with stable disease (2) following additional treatment. Conclusions: 1. MPCV is a tolerable regimen which can be given more aggressively than standard PCV. 2. There is minimal risk of early disease progression with MPCV. 3. Results support a prospective trial comparing MPCV to RT in patients with progressive unresectable LGG, and use of MPCV as salvage therapy for patients who fail RT. No significant financial relationships to disclose.
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Hermand, P., I. Mouro, M. Huet, C. Bloy, K. Suyama, J. Goldstein, JP Cartron, and P. Bailly. "Immunochemical characterization of rhesus proteins with antibodies raised against synthetic peptides." Blood 82, no. 2 (July 15, 1993): 669–76. http://dx.doi.org/10.1182/blood.v82.2.669.669.

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Abstract Rabbit polyclonal antibodies were raised against synthetic peptides corresponding to hydrophilic regions of the human Rhesus (Rh) IX cDNA- encoded polypeptide predicted to be extracellularly or intracellularly exposed in the topologic model of the Rh blood group protein. Four antibodies encompassing residues 33–45 (MPC1), 224–233 (MPC4), 390–404 (MPC6), and 408–416 (MPC8) were characterized and compared with a polyclonal anti-Rh protein obtained by immunization with purified Rh proteins. All antibodies had specificity for authentic Rh polypeptides and reacted on Western blot with Rh proteins immunoprecipitated with human monoclonal anti-RhD, -c, and -E. MPC1, but not the other antibodies, agglutinated all human erythrocytes except Rhnull and Rhmod cells, which either lack totally or are severely deficient in Rh proteins, respectively. Immunoblotting analysis with membrane proteins from common and rare variants showed that MPC1 and MPC8 reacted in Western blot with 32-Kd Rh polypeptides from all common red blood cells except those from Rhnull and Rhmod, indicating that peptide regions 33– 45 and 408–416 may be common to several if not all Rh proteins, whatever the Rh blood group specificity. MPC4 reacted only with membrane preparations from cells carrying the E antigen, whereas MPC6 recognized preferentially the Rh proteins from E and Ee preparations, suggesting that the protein encoded by the RhIXb cDNA carries the E and/or e antigen(s). Immunoadsorption experiments using inside-out or right-side-out sealed vesicules from DccEE red blood cells as competing antigen showed that the MPC6 and MPC8 antibodies bound only to the cytoplasmic side of the erythrocyte membrane, thus providing evidence for the intracellular orientation of the C-terminal 27 residues of the Rh polypeptides. Attempts to transiently or stably express the Rh polypeptides. Attempts to transiently or stably express the Rh cDNA in eukaryotic cells were largely unsuccessful, suggesting that Rh antigen expression at the cell surface requires correct transport and/or folding of the Rh proteins, possibly as a complex with one-membrane proteins of the Rh cluster that are lacking in Rhnull cells.
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Hermand, P., I. Mouro, M. Huet, C. Bloy, K. Suyama, J. Goldstein, JP Cartron, and P. Bailly. "Immunochemical characterization of rhesus proteins with antibodies raised against synthetic peptides." Blood 82, no. 2 (July 15, 1993): 669–76. http://dx.doi.org/10.1182/blood.v82.2.669.bloodjournal822669.

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Rabbit polyclonal antibodies were raised against synthetic peptides corresponding to hydrophilic regions of the human Rhesus (Rh) IX cDNA- encoded polypeptide predicted to be extracellularly or intracellularly exposed in the topologic model of the Rh blood group protein. Four antibodies encompassing residues 33–45 (MPC1), 224–233 (MPC4), 390–404 (MPC6), and 408–416 (MPC8) were characterized and compared with a polyclonal anti-Rh protein obtained by immunization with purified Rh proteins. All antibodies had specificity for authentic Rh polypeptides and reacted on Western blot with Rh proteins immunoprecipitated with human monoclonal anti-RhD, -c, and -E. MPC1, but not the other antibodies, agglutinated all human erythrocytes except Rhnull and Rhmod cells, which either lack totally or are severely deficient in Rh proteins, respectively. Immunoblotting analysis with membrane proteins from common and rare variants showed that MPC1 and MPC8 reacted in Western blot with 32-Kd Rh polypeptides from all common red blood cells except those from Rhnull and Rhmod, indicating that peptide regions 33– 45 and 408–416 may be common to several if not all Rh proteins, whatever the Rh blood group specificity. MPC4 reacted only with membrane preparations from cells carrying the E antigen, whereas MPC6 recognized preferentially the Rh proteins from E and Ee preparations, suggesting that the protein encoded by the RhIXb cDNA carries the E and/or e antigen(s). Immunoadsorption experiments using inside-out or right-side-out sealed vesicules from DccEE red blood cells as competing antigen showed that the MPC6 and MPC8 antibodies bound only to the cytoplasmic side of the erythrocyte membrane, thus providing evidence for the intracellular orientation of the C-terminal 27 residues of the Rh polypeptides. Attempts to transiently or stably express the Rh polypeptides. Attempts to transiently or stably express the Rh cDNA in eukaryotic cells were largely unsuccessful, suggesting that Rh antigen expression at the cell surface requires correct transport and/or folding of the Rh proteins, possibly as a complex with one-membrane proteins of the Rh cluster that are lacking in Rhnull cells.
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Rabelo, Luis, Serge Sala-Diakanda, John Pastrana, Mario Marin, Sayli Bhide, Oloruntomi Joledo, and Jorge Bardina. "Simulation Modeling of Space Missions Using the High Level Architecture." Modelling and Simulation in Engineering 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/967483.

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This paper discusses an environment being developed to model a mission of the Space Launch System (SLS) and the Multipurpose Crew Vehicle (MPCV) being launched from Kennedy Space Center (KSC) to the International Space Station (ISS). Several models representing different phases of the mission such as the ground operations processes, engineered systems, and range components such as failure tree, blast, gas dispersion, and debris modeling are explained. These models are built using different simulation paradigms such as continuous, system dynamics, discrete-event, and agent-based simulation modeling. The High Level Architecture (HLA) is the backbone of this distributed simulation. The different design decisions and the information fusion scheme of this unique environment are explained in detail for decision-making. This can also help in the development of exploration missions beyond the International Space Station.
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Tiburcio, Patricia, Balazs Murnyak, Kimberly Coffman, and Eric Huang. "DDRE-18. THE MITOCHONDRIAL PYRUVATE CARRIER—A METABOLIC TARGET OF MALIGNANT GLIOMA." Neuro-Oncology Advances 3, Supplement_1 (March 1, 2021): i10. http://dx.doi.org/10.1093/noajnl/vdab024.040.

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Abstract Metabolic reprogramming has been recognized as crucial to the survival and proliferation of cancer cells through the reduction of glucose oxidation (the Warburg effect) and diversion of pyruvate and glycolytic metabolites to fuel anabolic processes. The mitochondrial pyruvate carrier (MPC) protein complex, consisting of MPC1 and MPC2, has been identified as essential for pyruvate transport into mitochondria. In most human cancers, MPC1 is frequently deleted or downregulated and, therefore, the MPC activity is low. Restoration of MPC levels increases pyruvate oxidation and markedly inhibits tumor growth. Despite being tumor suppressive in general, the role of MPC in malignant glioma seems complex. We reported previously that unlike MPC1 in IDH-mutant glioma, MPC2 expression correlated with worsened survival. Interestingly, MPC2 homo-oligomers have been identified recently as an efficient autonomous pyruvate transporter, which can be inhibited by an insulin sensitizer rosiglitazone but not by the MPC heterotypic oligomer inhibitor UK-5099. In this study, we report that glioma cells show low MPC1 expression but much higher MPC2 expression. Analysis of glioma patient data revealed that the mean MPC2 expression increased in a grade-dependent fashion whereas the mean MPC1 expression remained essentially low, thereby resulting in an increased MPC2/MPC1 ratio in association with glioma progression. Importantly, we show that malignant glioma cells are extremely sensitive to the mitochondrion-specific, PPARγ-sparing insulin sensitizer mitoglitazone but not UK-5099 whereas MPC-proficient glial cells are highly responsive to the latter, indicating MPC2 as an alternative pyruvate transporter in glioma. Furthermore, the addition of glutamate fully rescues the growth arrest of Mpc1-/- murine glial cells, suggesting the involvement of cerebral cortex-specific microenvironment in glioma growth. We are employing newly developed RCAS/tva Mpc1fl/fl mouse models to test therapeutic targeting of Mpc2 in spontaneously developed glioma.
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Karsy, Michael, Jian Guan, and L. Eric Huang. "Prognostic role of mitochondrial pyruvate carrier in isocitrate dehydrogenase–mutant glioma." Journal of Neurosurgery 130, no. 1 (March 2018): 56–66. http://dx.doi.org/10.3171/2017.9.jns172036.

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OBJECTIVEGliomas are one of the most common types of primary brain tumors. Recent studies have supported the importance of key genetic alterations, including isocitrate dehydrogenase (IDH) mutations and 1p19q codeletion, in glioma prognosis. Mutant IDH produces 2-hydroxyglutarate from α-ketoglutarate, a key metabolite of the Krebs cycle. The mitochondrial pyruvate carrier (MPC) is composed of MPC1 and MPC2 subunits and is functionally essential for the Krebs cycle. The authors sought to explore the impact of MPC1 and MPC2 expression on patient prognosis.METHODSGenomic and clinical data in patients with lower-grade glioma (WHO grades II and III) from The Cancer Genome Atlas (TCGA) were evaluated using Kaplan-Meier analysis and hazards modeling. Validation was conducted with additional data sets, including glioblastoma.RESULTSA total of 286 patients with lower-grade glioma (mean age 42.7 ± 13.5 years, 55.6% males) included 54 cases of IDH–wild type (18.9%); 140 cases of IDH-mutant, 1p19q-intact (49.0%); and 85 cases of IDH-mutant, 1p19q-codeleted (29.7%) tumors. Kaplan-Meier analysis showed that an MPC1 z-score > 0 distinguished better survival, particularly in IDH-mutant (p < 0.01) but not IDH–wild type tumors. Conversely, an MPC2 z-score > 0 identified worsened survival, particularly in IDH-mutant (p < 0.01) but not IDH–wild type tumors. Consistently, neither MPC1 nor MPC2 was predictive in a glioblastoma data set containing 5% IDH-mutant cases. Within the IDH-stratified lower-grade glioma data set, MPC1 status distinguished improved survival in 1p19q-codeleted tumors (p < 0.05), whereas MPC2 expression delineated worsened survival in 1p19q-intact tumors (p < 0.01). A hazards model identified IDH and 1p19q status, age (p = 0.01, HR = 1.03), Karnofsky Performance Scale (KPS) score (p = 0.03, HR = 0.97), and MPC1 (p = 0.003, HR = 0.52) but not MPC2 (p = 0.38) as key variables affecting overall survival. Further validation confirmed MPC1 as an independent predictor of lower-grade glioma. A clinical risk score using IDH and 1p19q status, age, KPS score, and MPC1 and MPC2 z-scores defined 4 risk categories for lower-grade glioma; this score was validated using a secondary glioma data set.CONCLUSIONSThese results support the importance of MPC, especially MPC1, in improving prognostication of IDH-mutant tumors. The generation of a risk score system directly translates this finding to clinical application; however, further research to improve the molecular understanding of the role of MPC in the metabologenomic regulation of gliomas is warranted.
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Bricker, Daniel K., Eric B. Taylor, John C. Schell, Thomas Orsak, Audrey Boutron, Yu-Chan Chen, James E. Cox, et al. "A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast,Drosophila, and Humans." Science 337, no. 6090 (May 24, 2012): 96–100. http://dx.doi.org/10.1126/science.1218099.

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Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as essential for mitochondrial pyruvate transport in yeast,Drosophila, and humans. Mpc1 and Mpc2 associate to form an ~150-kilodalton complex in the inner mitochondrial membrane. Yeast andDrosophilamutants lackingMPC1display impaired pyruvate metabolism, with an accumulation of upstream metabolites and a depletion of tricarboxylic acid cycle intermediates. Loss of yeast Mpc1 results in defective mitochondrial pyruvate uptake, and silencing ofMPC1orMPC2in mammalian cells impairs pyruvate oxidation. A point mutation inMPC1provides resistance to a known inhibitor of the mitochondrial pyruvate carrier. Human genetic studies of three families with children suffering from lactic acidosis and hyperpyruvatemia revealed a causal locus that mapped toMPC1, changing single amino acids that are conserved throughout eukaryotes. These data demonstrate that Mpc1 and Mpc2 form an essential part of the mitochondrial pyruvate carrier.
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Le, Xuyen H., Chun-Pong Lee, and A. Harvey Millar. "The mitochondrial pyruvate carrier (MPC) complex mediates one of three pyruvate-supplying pathways that sustain Arabidopsis respiratory metabolism." Plant Cell 33, no. 8 (June 17, 2021): 2776–93. http://dx.doi.org/10.1093/plcell/koab148.

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Abstract Malate oxidation by plant mitochondria enables the generation of both oxaloacetate and pyruvate for tricarboxylic acid (TCA) cycle function, potentially eliminating the need for pyruvate transport into mitochondria in plants. Here, we show that the absence of the mitochondrial pyruvate carrier 1 (MPC1) causes the co-commitment loss of its putative orthologs, MPC3/MPC4, and eliminates pyruvate transport into Arabidopsis thaliana mitochondria, proving it is essential for MPC complex function. While the loss of either MPC or mitochondrial pyruvate-generating NAD-malic enzyme (NAD-ME) did not cause vegetative phenotypes, the lack of both reduced plant growth and caused an increase in cellular pyruvate levels, indicating a block in respiratory metabolism, and elevated the levels of branched-chain amino acids at night, a sign of alterative substrate provision for respiration. 13C-pyruvate feeding of leaves lacking MPC showed metabolic homeostasis was largely maintained except for alanine and glutamate, indicating that transamination contributes to the restoration of the metabolic network to an operating equilibrium by delivering pyruvate independently of MPC into the matrix. Inhibition of alanine aminotransferases when MPC1 is absent resulted in extremely retarded phenotypes in Arabidopsis, suggesting all pyruvate-supplying enzymes work synergistically to support the TCA cycle for sustained plant growth.
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Phelix, Clyde F., Allen K. Bourdon, Jason L. Dugan, Greg Villareal, and George Perry. "MSDC-0160 and MSDC-0602 Binding with Human Mitochondrial Pyruvate Carrier (MPC) 1 and 2 Heterodimer." International Journal of Knowledge Discovery in Bioinformatics 7, no. 2 (July 2017): 43–67. http://dx.doi.org/10.4018/ijkdb.2017070103.

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The mitochondrial pyruvate carrier (MPC) is a novel target for therapeutic drugs to treat Alzheimer's and Parkinson's disease, diabetes mellitus, and non-alcoholic steatohepatitis (NASH). Metabolic Solutions Development Company (MSDC) has two thiazolidinediones, MSDC-0160 and MSDC-0602, in the pipeline. This report describes results for a MPC1/2 heterodimer homology model. The FASTA sequences for MPC1 and MPC2 were accessed from UniProt and submitted to RaptorX, resulting in best candidate monomeric “protein data base” files for each. One mutant form of MPC1, L36I, was also processed. These were submitted to PyDock to generate best candidate MPC1/2 heterodimer models that were used for ligand docking analyses with AutoDock Vina and “Rosetta Online Server that Includes Everyone” (ROSIE). Multiple binding sites for pyruvate and both drugs were found on both MPC1 and MPC2 subunits with drugs having nearly double the affinity in each case except the intermediate and open-in states for the L36I mutant transporter.
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Sheeran, Freya L., Julie Angerosa, Norman Y. Liaw, Michael M. Cheung, and Salvatore Pepe. "Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure." Oxidative Medicine and Cellular Longevity 2019 (February 7, 2019): 1–11. http://dx.doi.org/10.1155/2019/4532592.

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Pyruvate dehydrogenase (PDH) complex, a multienzyme complex at the nexus of glycolytic and Krebs cycles, provides acetyl-CoA to the Krebs cycle and NADH to complex I thus supporting a critical role in mitochondrial energy production and cellular survival. PDH activity is regulated by pyruvate dehydrogenase phosphatases (PDP1, PDP2), pyruvate dehydrogenase kinases (PDK 1-4), and mitochondrial pyruvate carriers (MPC1, MPC2). As NADH-dependent oxidative phosphorylation is diminished in systolic heart failure, we tested whether the left ventricular myocardium (LV) from end-stage systolic adult heart failure patients (n=26) exhibits altered expression of PDH complex subunits, PDK, MPC, PDP, and PDH complex activity, compared to LV from nonfailing donor hearts (n=21). Compared to nonfailing LV, PDH activity and relative expression levels of E2, E3bp, E1α, and E1βsubunits were greater in LV failure. PDK4, MPC1, and MPC2 expressions were decreased in failing LV, whereas PDP1, PDP2, PDK1, and PDK2 expressions did not differ between nonfailing and failing LV. In order to examine PDK4 further, donor human LV cardiomyocytes were induced in culture to hypertrophy with 0.1 μM angiotensin II and treated with PDK inhibitors (0.2 mM dichloroacetate, or 5 mM pyruvate) or activators (0.6 mM NADH plus 50 μM acetyl CoA). In isolated hypertrophic cardiomyocytesin vitro, PDK activators and inhibitors increased and decreased PDK4, respectively. In conclusion, in end-stage failing hearts, greater expression of PDH proteins and decreased expression of PDK4, MPC1, and MPC2 were evident with higher rates of PDH activity. These adaptations support sustained capacity for PDH to facilitate glucose metabolism in the face of other failing bioenergetic pathways.
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Dissertations / Theses on the topic "MPCV"

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Guise, Aurore. "Contribution à la compréhension de l'épitaxie du diamant élaboré par MPCVD assisté par polarisation sur silicium : étude de la réactivité du substrat et influence des étapes de prétraitement sur le dépôt." Thesis, Vandoeuvre-les-Nancy, INPL, 2008. http://www.theses.fr/2008INPL076N/document.

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Le but de cette étude est de mieux appréhender les phénomènes régissant l’épitaxie du diamant élaboré par MPCVD assisté pas polarisation sur silicium. Elle s’articule en deux grands axes : une première approche qualitative sur la réactivité du substrat et une seconde approche plus quantitative relative à l’influence des étapes de prétraitement sur le dépôt. L’importance de la mise en œuvre d’un protocole rigoureux est mise en exergue dans ce travail. Le rôle des différentes étapes de préparation des substrats de silicium allant du nettoyage ex situ jusqu’à la croissance du diamant en passant par le nettoyage in situ par plasma H2 et la polarisation a été étudiée grâce à des techniques d’investigations telles que la microscopie électronique à balayage et à transmission, la spectroscopie de photoélectrons X, la microscopie à force atomique et la diffraction en faisceau rasant d’électrons haute énergie. Ces analyses ont mis en évidence l’apparition de structures de type « voids » associées à la formation de carbure de silicium dès l’étape de décapage hydrogène. La formation de carbone amorphe dans les premiers instants de la germination du diamant semble être corrélée à la quantité de diamant constatée après croissance, l’importance du flux d’ions pendant l’étape de polarisation sur les densités a été démontrée en parallèle. Des taux d’épitaxie jusqu'à près de 30% ont été atteints grâce à l’optimisation du couple temps/tension de polarisation ou à une carburation du substrat précédant la polarisation. La technique d’analyse de diffraction d’électrons en faisceau convergent sur des films de diamant s’est révélée adaptée à l’étude statistique de l’orientation des cristaux
The goal of this study is to better apprehend the phenomena governing bias assisted MPCVD diamond epitaxy on silicon. It is organized into two main parts: a first qualitative approach on the reactivity of the substrate and a second approach more quantitative related to the pretreatment stages influence on the deposit. The importance of a rigorous protocol is put forward in this work. The role of the various stages of silicon substrates preparation going from ex situ cleaning, in situ cleaning (plasma H2), bias until diamond growth was studied thanks to investigations techniques such as transmission and scanning electron microscopies, X-ray photoelectrons spectroscopy, atomic force microscopy, reflexion high energy electrons diffraction. These analyses highlighted the appearance of structures of the type “voids” associated with the silicon carbide formation from the hydrogen etching stage. The amorphous carbon formation in the first moments of diamond nucleation seems to be correlated with the diamond quantity measured after growth, the importance of ions flow during nucleation stage on the densities was shown in parallel. Epitaxy ratio up to 30% were reached thanks to the optimization of the couple time/biasing or carburation of the substrate preceding bias. The convergent beam electron diffraction analysis of diamond films appeared well adapted to the statistical study of crystals orientation
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Lima, Marcelo Lopes de. "Distributed satisficing MPC." reponame:Repositório Institucional da UFSC, 2014. https://repositorio.ufsc.br/xmlui/handle/123456789/122752.

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Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2013.
Made available in DSpace on 2014-08-06T17:19:47Z (GMT). No. of bitstreams: 1 325382.pdf: 1772540 bytes, checksum: 52b8f812eaccad89bad0282c1c7c5db4 (MD5)
Abstract : To obtain a Pareto-optimal solution, the classical cooperative MPC implementsa categorical altruism imposed by a fixed global cost sharedby all the local controllers. Instead, this thesis implements a situationalaltruism where a global cost, neither imposed nor fixed, emerges fromconvex local costs and local specifications. The satisficing controllersemploy a distributed algorithm to find a solution that lies in a convexregion that is satisfactory and sufficient for all controllers (satisficing= satisfy + suffice), while optimizing in the direction of the analyticcenter of such a region. The system is modeled as being a network oflinear subsystems, coupled by their inputs, and the algorithm uses adistributed interior-point method to avoid fixed points when the constraintsare also coupled. The optimal solution of the satisficing MPC,besides Pareto-optimal, gives more importance to the controllers witha worst performance at the moment. Situational altruism permits amore balanced division of resources, avoiding the exploitation of onecontroller by the others. The satisficing MPC is shown to be stabilizingeven if suboptimal, provided that it is satisficing. To this end,stabilizing constraints are added to the basic formulation.
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Kück, Corvin. "MPC Design For Autonomous Drifting." Thesis, KTH, Reglerteknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-215873.

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The goal of this thesis is to evaluate the performance of different controllers to keep a remotecontrolledvehicle in a sustained drift. A bicycle model and an empirical tyre model are used formodelling the vehicle. The parameters for the used Fiala tyre model are experimentally identifiedand the simulation results of the modelled vehicle are compared to measured experimental data. Itfollows a stability analysis of the modelled system. The system is then linearized around one ofthe drift equilibria to allow controller design. A state feedback controller is designed to stabilizethe system, the controller gains are optimized using a Linear Quadratic Regulator (LQR) design,subsequently a Model Predictive Controller (MPC) is designed. Finally, the performance of the 3controllers is evaluated for a simulation with a disturbance acting on the system.
Målet med denna studie är att undersöka prestandan för olika reglerstrukturer när en radiostyrd bildriftar. En cykelmodell och en empirisk däcksmodell används för att modellera bilen.Parametrarna som användes för Fiala däcksmodellen är framtagna genom experiment ochsimuleringsresultatet av den modellerade bilen jämförs med verklig data. En stabilitetsanalys ärockså gjord för det modellerade systemet. Systemet är sedan linjäriserat runt ett jämviktsläge fördrifting för att kunna skapa en regulator. En tillståndsregulator med återkoppling används för attstabilisera systemet. Förstärkningskonstanterna för regulatorn optimeras med linjärkvadratiskreglering och sedan designas en modell prediktiv kontroller. Slutligen utvärderas prestandan,genom simulering, hos de tre regulatorerna när en störning finns i systemet.
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Zdychynec, Tomáš. "Zadávání veřejných zakázek na MPSV v letech 2011-2015." Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-262264.

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The aim of the thesis is to evaluate the system of procurement at the Ministry of Labour and Social affairs between 2011-2015. The first part defines important terms in the issue of public procurement from different points of view. The second part deals with internal legislation regulating procurement at the Ministry of Labour and Social affairs and the procurement system analysis of over-threshold (below-threshold) procurement and small-scale public contracts. The last part analyzes the data of public contracts between 2011-2015. The right system adjustment of procurement at the Ministry of Labour and Social affairs is questioned.
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Jimoh, Mohammed Tajudeen. "A vision for MPC performance maintenance." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4739/.

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Model predictive control (MPC) is an advanced control that has found widespread use in industries, particularly in process industries like oil refining and petrochemicals. Although the basic premise behind MPC is easy to comprehend, its inner workings are still generally viewed or regarded as too advanced for actual plant operator understanding. This lack of understanding is exposed when MPC performance deteriorates sometime after commissioning, as is often the case in some commercially operated process plants. Currently operators might have difficulty over reasoning about MPC performance degradation and formulating steps to investigate the cause. A tool is described that aims to make MPC more transparent to the operators. Commonly reported causes of MPC performance degradation are discussed and ways in which the operator can recognise them when they occur are outlined. Issues that are addressed include: making the set of controlled variables to be used for a given set of manipulated variables simpler and clearer; ways to recognise when a MPC controller is performing poorly and to identify the source of performance deterioration. An aim is to determine under what instances the operator can return the MPC performance to previous levels or request for specialist support or simply switch the MPC off. A goal is to avoid the kind of often reported situation where the operator gets worried that the controller is deteriorating and ends up taking knee jerk actions that cause further problems in MPC. At the top of the maintenance tool hierarchy is the trends comparison group, where MPC reference graphical performance trends are compared with actual graphical performance trends counterpart. If any abnormality is observed in these trends, the operator is encouraged to choose an option from a list of preliminary diagnostic questions contained in a group below trends comparison group, which best describes the observed abnormality. Each abnormality is associated with a list of suspected causes. When a suspected cause is chosen from the associated list, the operator is led to the symptoms investigation window, which contains scripts detailing steps for systematic examination of each symptom, with a view to either rejecting or confirming the suspicion. Assisted in the investigation are four background information windows: the virtual plant without MPC window, the virtual plant with MPC window, the transfer function matrix window and steady state gain, relative gain array (RGA) and relative weight array (RWA) window. The windows contain information and guidance that the operator might refer to from time to time during symptom investigation. Development of the maintenance tool is still at the design stage. The key components described have been research implementing MPC on three nonlinear process models, a continuous stirred tank reactor (CSTR), an evaporator process and a fluid catalytic cracking unit (FCCU). Case studies representing different MPC degradation scenarios are simulated, followed by a systematic procedure for diagnosing, isolating and recovering from such degradation, based on assumed operator’s perspective and expert’s technical reasoning. The knowledge gained from the case studies is used to develop an outline of a vision for a data-driven model predictive maintenance tool to help the operator make sensible judgements about performance degradation, the form and direction of diagnosis and fault isolation, and possibly, the recovery procedure.
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Klaesson, Filip, and John Friberg. "Autonomous Overtaking Using Reachability Analysisand MPC." Thesis, KTH, Skolan för teknikvetenskap (SCI), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230162.

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The era of autonomous cars is on the rise. Asdrivers lose control of the steering wheel, it is crucial that thecars themselves can guarantee safety for all traffic participants.This study aims to design a complete control system that cansafely perform an overtaking maneuver. To guarantee safety ofthe maneuver, reachability calculations will be carried out andanalyzed. The overtaking will be planned by using the modelpredictive control, MPC, framework. To complete the controlsystem a modified proportional controller will be designed totrack the planned path. The control system is implemented inMATLAB and the entire overtaking maneuver is simulated. Theresults show that the designed control framework successfullyperforms the overtaking on a straight two-lane highway in asafe manner.
Autonoma bilar är på frammarsch. När förare inte längre har kontroll över ratten är det avgörande att bilarna själva kan garantera säkerheten för alla trafikanter. Denna studie syftar till att utforma ett komplett styrsystem som kan utföra en säker omkörning. Omkörningen planeras med hjälp av ramverket för modell-prediktiv reglering. För att garantera säkerhet används nåbarhetsanalys. Slutligen utformas en modifierad proportionell regulator för att följa den planerade omkörningsvägen. Styrsystemet har implementerats i MATLAB och hela omkörningen har simulerats. Resultaten visar att det konstruerade styrsystemet utför omkörningen på en rak motorväg med två filer på ett säkert och framgångsrikt sätt.
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Rueda, Juan. "Evaluation of The Biodegradability and Toxicity of PCA and mPCA." Master's thesis, University of Central Florida, 2013. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5696.

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The main types of hypergolic propellants used at Kennedy Space Center (KSC) are hydrazine (HZ) and monomethylhydrazine (MMH). HZ and MMH are classified as hazardous materials and they are also known to be potentially carcinogenic to humans; therefore, handling these substances and their waste is strictly regulated. The wastes streams from HZ and MMH have been estimated to be the main hazardous wastes streams at KSC. Currently at KSC these wastes are first neutralized using citric acid and then they are transported on public roads for incineration as hazardous materials. A new method using alpha ketoglutaric acid (AKGA) was proposed to treat HZ and MMH wastes. From the reaction of AKGA with HZ and MMH two stable products are formed, 1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid (PCA) and l-methyl-1,4,5,6-tetrahydro-6-oxo-3-pyridazinecarboxylic acid (mPCA), respectively. The cost of purchasing AKGA is greater than the cost of purchasing citric acid; thus, AKGA can only become a cost effective alternative for the treatment of HZ and MMH wastes if the products of the reactions (PCA and mPCA) can be safely disposed of into the sewage system without affecting the treatment efficiency and effluent quality of the wastewater treatment plant (WWTP). In this research mPCA and PCA were analyzed for acute toxicity using fish and crustaceans as well as their effect on the wastewater treatment efficiency and viability using AS microbes, and their biodegradability by AS organisms. Acute toxicity on fish and crustaceans was investigated according to the methods for acute toxicity by USEPA (USEPA Method EPA-821-R-02-012) using Ceriodaphnia dubia (96 hours) and Pimephales promelas (96 hours) as the test organisms. The effect of mPCA and PCA in the treatment efficiency and viability were estimated from respiration inhibition tests (USEPA Method OCSPP 850.3300) and heterotrophic plate counts (HPCs). Lastly, the biodegradability of mPCA and PCA was assessed using the Closed Bottle Test (USEPA Method OPPTS 835.3110). For mPCA, the 96 hours LC50 for C. dubia was estimated at 0.77 ± 0.06 g/L (with a 95% confidence level) and the NOEC was estimated at 0.5 g/L. For P. promelas, the LC50 was above 1.5 g/L but it was noticed that mPCA had an effect on their behavior. Abnormal behavior observed included loss of equilibrium and curved spine. The NOEC on the fish was estimated at 0.75 g/L. PCA did not exhibit a significant mortality on fish or crustaceans. The LC50 of PCA in P. promelas and C. dubia was > 1.5 g/L and the NOEC was 1.5 g/L for both organisms. An Inhibitory effect on the heterotrophic respiration of activated sludge organisms was not observed after exposing them for 180-min to PCA and mPCA at concentrations of up to 1.5 g/L compared to the blank controls. Overall the impact of PCA and mPCA on total respiration rates was small, and only observed at 1,500 mg/L if at all. The difference was apparently caused by inhibition of nitrification rather than heterotrophic inhibition. However due to the variability observed in the measurements of the replicates, it is not possible to firmly conclude that PCA or mPCA at 1,500 mg/L was inhibitory to nitrification. Based on the results from the HPCs, mPCA and PCA did not affect the viability of heterotrophic organisms at 750 mg/L. In the BOD-like closed bottle test using a diluted activated sludge mixed liquor sample, the AS microorganisms were capable of biodegrading up to 67% of a 2 mg/L concentration of PCA (with respect to its theoretical oxygen demand, or ThOD) in 28 days. No biodegradation was observed in the samples containing 2 and 5 mg/L of mPCA after 28 days of incubation using a diluted activated sludge mixed liquor sample as inoculum. The results of this study show that mPCA is more toxic than PCA to Ceriodaphnia dubia and Pimephales promelas. However neither mPCA nor PCA had an effect on the heterotrophic respiration of an AS mixed liquor sample at 1.5 g/L and there was probably no significant inhibition of the nitrification respiration. Samples of PCA and mPCA at 2 and 5 mg/L could not be completely degraded (with respect to their total theoretical oxygen demand) by dilute AS biomass during a 28 day incubation period. mPCA did not show significant degradation in the two different biodegradation tests performed.
M.S.Env.E.
Masters
Civil, Environmental, and Construction Engineering
Engineering and Computer Science
Environmental Engineering
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8

Ali, Samira Abdulla. "Investigation of a novel MPCM-S based PV/T system." Thesis, De Montfort University, 2017. http://hdl.handle.net/2086/14948.

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In order to meet energy conservation targets and minimize global warming effects, this research is aimed to rise the efficiency of the PV/T system. This research investigates the usage of microencapsulated phase change slurry (MPCM-S) to replace conventional cooling fluids such as water. The phase change materials (PCMs) are encapsulated in a polymer shell forming microencapsulated phase change materials (MPCM) to prevent leakage of the PCMs as well as increasing the thermal conductivity. Mixtures of (5%, 10% and 15%) of microencapsulated phase change materials in water (slurries) were investigated. The use of phase change materials (PCM) improves heat absorption from the PV module due to their high latent heat, consequently increasing thermal output of the system, and electrical output because the PV panel temperature is reduced. The research started with an intensive literature review covering all elements involved, and then the conceptual design of the experimental rig was developed. Theoretical investigations including a steady-state computerized simulation module were developed, this simulation validated depending on a previous research and showed good agreement with results from that published experimental study. This suggested that the computer module could successfully predict the operational performance of the module with satisfactory accuracy. A series of laboratory-based tests were conducted for a wide range of conditions and slurry concentrations. The results were compared to the computer simulation with the same parameters. It was found that the root mean square percentage deviations (RMSPE) between experimental and simulated results were generally under 4%, so considered acceptable for engineering application of PV/T system. A slurry concentration of 10% was found to give the best results. Under operational conditions of 10% MPCM concentration, 3000 Reynolds number and 600W/m2 solar radiation, an experimental test was conducted. The electricity and heat outputs of the system were 108 and 520 W respectively, the associated electrical and thermal efficiency were 14.1% and 68.8%, giving an overall efficiency of 82.9%. The economic analysis was carried out to investigate the feasibility of the MPCM-S based PV/T system in two different climates of Europe. It showed that the system generates higher annual electrical and heat of 488.29 and 2184.93 kWh in a hot climate (using Madrid as an example) than the annual electrical and heat of 323.12 and 1262.1 kWh for colder climate (Stockholm as an example). Consequently, the life cycle cost of MPCM-S based system per kWh were -0.068 and 0.019 GBP for Madrid and Stockholm respectively, and for water-based PV/T system were -0.038 and 0.028 GBP for Madrid and Stockholm respectively. Finally, the environmental effect of the system was investigated by calculating the life cycle CO2 emission reduction of MPCM-S based PV/T system in both climates, they were 11.75 and 6.9 tonnes for Madrid and Stockholm respectively, and for water-based PV/T system were 7 and 3.5 tonnes for Madrid and Stockholm respectively. Generally, the MPCM-S based PV/T system is more efficient than the conventional water-based PV/T systems as predicted, especially if it runs with 10% MPCM-S. It delivers higher electrical and heat outputs in hot climates in comparison with colder climates of Europe, consequently better economically and environmentally.
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Reis, Alexandre Francisco Pereira dos. "Optimização do sistema MPCVD para deposição de filmes de diamante." Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/6810.

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Mestrado em Engenharia Mecânica
O presente trabalho teve como principal objectivo, o estudo e montagem de um reactor, para deposição de filmes de diamante a partir da fase vapor, activado por um gerador de microondas. Do Inglês, microwave plasmaassisted chemical vapour deposition (MPCVD). Numa primeira fase do estudo, foi necessária a pesquisa e obtenção de conhecimento na área do CVD, dos diferentes tipos de tecnologia existentes bem como um estudo dos mecanismos físico-químicos de crescimento de filmes de diamante. Numa segunda fase, paralelamente acompanhada de pesquisa teórica, foi efectuada a montagem física do sistema, em que foram necessárias constantes limpezas, reparações e compras de componentes. Por fim, o sistema foi testado nos parâmetros possíveis, não tendo sido criadas amostras experimentais. Foram ainda calculadas optimizações a nível mecânico, de vácuo, atmosférico e térmico.
This work had as main purpose, the study, installation and optimization of a microwave plasma-assisted reactor for chemical deposition of films based on carbon-phase vapor (MPCVD). In the first phase of the study, it was necessary to obtain knowledge and research in the area of CVD, the different types of existing technology as well as a study of the physicochemical mechanisms of diamond film growth. In a second phase, accompanied by parallel theoretical research, the system was physically assembled, what required constant cleaning, repairs and purchases of components. Finally, the system was tested at the possible parameters in spite that there were not created any experimental samples. Mechanical, vacuum, atmospheric and thermal optimizations were also calculated.
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Ulip, Jan. "Analýza výdajů kapitoly státního rozpočtu MPSV v letech 2000 -2010." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-124577.

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Diploma thesis is focused on the analysis of expenditure of the state budget of the Ministry of labour and social affairs in the years 2000 to 2010. This thesis explores the changing structure of those expenses and tries to answer the question whether the political cycle and the power of coalitions significant impact on spending in this chapter. It also addresses the issue of sustainability of public finances.
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Books on the topic "MPCV"

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Klaučo, Martin, and Michal Kvasnica. MPC-Based Reference Governors. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 1993.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 2008.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 2008.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 2008.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 2008.

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Ryan, Mark. Mazda MPV automotive repair manual. Somerset, England: Haynes Pub. Group, 1994.

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Hansen, Stephen. Delayed doves: MPC voting behaviour of externals. London: Centre for Economic Performance, London School of Economics and Political Science, 2008.

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The MPC and recent developments in monetary policy. London: Stationery Office, 2003.

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Robinson, P. L. The metaplectic representation, Mpc structures, and geometric quantization. Providence, R.I., USA: American Mathematical Society, 1989.

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Book chapters on the topic "MPCV"

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Griebel, Matt, Adam Johnson, Brent Erickson, Andrew Doan, Chris Flanigan, Jesse Wilson, Paul Bremner, Joel Sills, and Erica Bruno. "Orion MPCV E-STA Nonlinear Dynamics Uncertainty Factors." In Sensors and Instrumentation, Aircraft/Aerospace, Energy Harvesting & Dynamic Environments Testing, Volume 7, 1–7. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-47713-4_1.

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Chang, Chein-I. "A Quantitative Analysis of Mixed-to-Pure Pixel Conversion (MPCV)." In Hyperspectral Imaging, 161–78. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9170-6_9.

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Winkel, James P., James C. Akers, Vicente J. Suarez, Lucas D. Staab, and Kevin L. Napolitano. "Modal Survey of the MPCV Orion European Service Module Structural Test Article Using a Multi-axis Shake Table." In Topics in Modal Analysis & Testing, Volume 9, 347–58. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-74700-2_40.

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Hranicky, Wm Jack. "MPRV Environment." In Lithic Technology in the Middle Potomac River Valley of Maryland and Virginia, 32–55. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0615-7_2.

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Klaučo, Martin, and Michal Kvasnica. "Reference Governors." In MPC-Based Reference Governors, 1–5. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_1.

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Klaučo, Martin, and Michal Kvasnica. "Cascade MPC of Chemical Reactors." In MPC-Based Reference Governors, 113–32. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_10.

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Klaučo, Martin, and Michal Kvasnica. "Conclusions and Future Research." In MPC-Based Reference Governors, 133–35. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_11.

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Klaučo, Martin, and Michal Kvasnica. "Mathematical Preliminaries and General Optimization." In MPC-Based Reference Governors, 9–14. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_2.

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Klaučo, Martin, and Michal Kvasnica. "Model Predictive Control." In MPC-Based Reference Governors, 15–34. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_3.

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Klaučo, Martin, and Michal Kvasnica. "Inner Loops with PID Controllers." In MPC-Based Reference Governors, 35–43. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17405-7_4.

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Conference papers on the topic "MPCV"

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Lamantea, Matteo Maria, and Claudio Finetto. "The MPCV-ESM Consumables Storage Subsystem." In 43rd International Conference on Environmental Systems. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2013. http://dx.doi.org/10.2514/6.2013-3492.

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Behruzi, Philipp, Diana Gaulke, Joerg Klatte, and Nicolas Fries. "Development of the MPCV ESM propellant tanks." In 51st AIAA/SAE/ASEE Joint Propulsion Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2015. http://dx.doi.org/10.2514/6.2015-4157.

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Hyatt, Andrew J., and Molly White. "Orion MPCV Continuum RCS Heating Augmentation Model Development." In 52nd Aerospace Sciences Meeting. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2014. http://dx.doi.org/10.2514/6.2014-0511.

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Daum, Jared, and Robert Gay. "Orion MPCV Touchdown Detection Threshold Development and Testing." In AIAA Guidance, Navigation, and Control (GNC) Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2013. http://dx.doi.org/10.2514/6.2013-4877.

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Rains, George, and Cynthia Cross. "Use of Heritage Hardware on Orion MPCV Exploration Flight Test One." In 42nd International Conference on Environmental Systems. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2012. http://dx.doi.org/10.2514/6.2012-3530.

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Sargusingh, Miriam. "MPCV Flight Suit Performance After an Uncontrolled Crew Cabin Depressurization Event." In 42nd International Conference on Environmental Systems. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2012. http://dx.doi.org/10.2514/6.2012-3644.

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Meiss, Jan-Hendrik, Jörg Weber, Thierry Kachler, Frank Quinn, and Jonathan Paisley. "Electrical Pressurization Concept for the Orion MPCV European Service Module Propulsion System." In AIAA SPACE 2015 Conference and Exposition. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2015. http://dx.doi.org/10.2514/6.2015-4636.

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Aggarwal, Pravin, and Patrick V. Hull. "Flight Vehicle Structural Design Processes for a Common Bulkhead and an MPCV Spacecraft Adapter." In 57th AIAA/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2016. http://dx.doi.org/10.2514/6.2016-0158.

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Aggarwal, Pravin, and Patrick V. Hull. "Flight Vehicle Structural Design Processes for a Common Bulkhead and an MPCV Spacecraft Adapter." In 56th AIAA/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2015. http://dx.doi.org/10.2514/6.2015-0704.

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Hickman, Heather. "Evolution of MPCV Service Module Propulsion and GN&C Interface Requirements between Constellation and European Service Module." In 50th AIAA/ASME/SAE/ASEE Joint Propulsion Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2014. http://dx.doi.org/10.2514/6.2014-3880.

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Reports on the topic "MPCV"

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Lajoie, John. PHENIX Muon Piston Calorimeter (MPC) APD and Prototype MPC Extension (MPC-EX) Tests. Office of Scientific and Technical Information (OSTI), June 2013. http://dx.doi.org/10.2172/1128068.

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Primas, Lori, Steve Gilbertson, Gregg Sullivan, and Russell Mitchell. Update on MPDV Diagnostic and Data [Slides]. Office of Scientific and Technical Information (OSTI), July 2021. http://dx.doi.org/10.2172/1810523.

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Christelis, Dimitris, Dimitris Georgarakos, Tullio Jappelli, Luigi Pistaferri, and Maarten van Rooij. Wealth Shocks and MPC Heterogeneity. Cambridge, MA: National Bureau of Economic Research, June 2019. http://dx.doi.org/10.3386/w25999.

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Low, Hamish, Peter Levell, Paul Fisher, and Thomas Crossley. MPCs through COVID: spending, saving and private transfers. The IFS, October 2020. http://dx.doi.org/10.1920/wp.ifs.2020.3520.

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Low, Hamish, Peter Levell, Paul Fisher, and Thomas Crossley. MPCs through COVID: spending, saving and private transfers. The IFS, February 2021. http://dx.doi.org/10.1920/wp.ifs.2021.321.

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Michael A. Bender, Martin Farach-Colton, and Bradley C. Kuszmaul. Final Report: Efficient Databases for MPC Microdata. Office of Scientific and Technical Information (OSTI), August 2011. http://dx.doi.org/10.2172/1048538.

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Auclert, Adrien, Bence Bardóczy, and Matthew Rognlie. MPCs, MPEs and Multipliers: A Trilemma for New Keynesian Models. Cambridge, MA: National Bureau of Economic Research, July 2020. http://dx.doi.org/10.3386/w27486.

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Low, Hamish, Peter Levell, Paul Fisher, and Thomas Crossley. MPCs in an economic crisis: spending, saving and private transfers. The IFS, August 2021. http://dx.doi.org/10.1920/wp.ifs.2021.2621.

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Ramsey, Monica, Dylan Scott, Charles Weiss, and Jeb Tingle. Development of magnesium phosphate cement (MPC) concrete mixture proportioning for airfield pavements : laboratory and field validation MPC test report. Engineer Research and Development Center (U.S.), February 2020. http://dx.doi.org/10.21079/11681/35475.

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J. Davis. 12 PWR ASSEMBLY MPC WASTE PACKAGE CRITICALITY ANALYSIS. Office of Scientific and Technical Information (OSTI), January 1996. http://dx.doi.org/10.2172/891573.

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