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Journal articles on the topic 'Mpox'

Author: Grafiati

Published: 31 May 2025

Last updated: 31 July 2025

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1

Hudu, Shuaibu A., Ahmed S. Alshrari, Aiman Al Qtaitat, and Mohd Imran. "VP37 Protein Inhibitors for Mpox Treatment: Highlights on Recent Advances, Patent Literature, and Future Directions." Biomedicines 11, no. 4 (2023): 1106. http://dx.doi.org/10.3390/biomedicines11041106.

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Monkeypox disease (Mpox) has threatened humankind worldwide since mid-2022. The Mpox virus (MpoxV) is an example of Orthopoxviruses (OPVs), which share similar genomic structures. A few treatments and vaccines are available for Mpox. OPV-specific VP37 protein (VP37P) is a target for developing drugs against Mpox and other OPV-induced infections such as smallpox. This review spotlights the existing and prospective VP37P inhibitors (VP37PIs) for Mpox. The non-patent literature was collected from PubMed, and the patent literature was gathered from free patent databases. Very little work has been

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Al-Shomrani, Mohammed M., Salihu S. Musa, and Abdullahi Yusuf. "Unfolding the Transmission Dynamics of Monkeypox Virus: An Epidemiological Modelling Analysis." Mathematics 11, no. 5 (2023): 1121. http://dx.doi.org/10.3390/math11051121.

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Monkeypox (mpox) is a zoonotic viral disease that has caused recurring outbreaks in West Africa. The current global mpox virus (mpoxv) epidemic in endemic and non-endemic areas has seriously threatened public health. In this study, we design an SEIR-based deterministic model that considers prodromal stage, differential infectivity, and hospitalisation to investigate the transmission behaviour of mpoxv, which could help enhance control interventions. The model is theoretically analyzed by computing essential epidemiological quantities/dynamics, such as the basic reproduction number, which estim

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Nadamuni, Mridula, and Lindsey Baden. "Mpox." New England Journal of Medicine 389, no. 10 (2023): e17. http://dx.doi.org/10.1056/nejmp2212931.

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Jafari, Kaileen, and George A. Woodward. "Mpox." Pediatric Emergency Care 39, no. 11 (2023): 883–89. http://dx.doi.org/10.1097/pec.0000000000003063.

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Abstract Human mpox (formerly known as monkeypox) is a zoonotic disease that causes a smallpox-like infection in humans. The mpox virus, the causative agent of mpox, was first reported to cause human disease in a 9-month-old infant in the Democratic Republic of the Congo in 1970. Since that time, periodic outbreaks in primarily endemic regions have occurred, typically secondary to transmission from wildlife reservoirs. However, in May 2022, after a rapid rise in worldwide cases in largely nonendemic countries, the World Health Organization declared mpox a Public Health Emergency of Internation

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Linfield, Rebecca Y., David J. G. Slusky, and Leon S. Moskatel. "The impact of Mpox virus incidence and Mpox virus first-dose vaccination on recent HIV testing." AIDS 38, no. 10 (2024): 1595–97. http://dx.doi.org/10.1097/qad.0000000000003919.

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Understanding the impact of Mpox incidence and Mpox first dose vaccination on recent HIV testing is critical to better address both epidemics. We conducted a regression analysis of Mpox incidence and Mpox first dose vaccinations with recent HIV testing during the 2022 Mpox epidemic. We found that increased Mpox first dose vaccination was associated with a decrease in recent HIV testing in men but not women. Mpox incidence was not associated with changes in HIV testing.

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Luo, Sitong, Kedi Jiao, Yuhang Zhang, et al. "Behavioral Intention of Receiving Monkeypox Vaccination and Undergoing Monkeypox Testing and the Associated Factors Among Young Men Who Have Sex With Men in China: Large Cross-Sectional Study." JMIR Public Health and Surveillance 10 (March 19, 2024): e47165. http://dx.doi.org/10.2196/47165.

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Background The worldwide human monkeypox (mpox) outbreak in 2022 mainly affected men who have sex with men (MSM). In China, young men who have sex with men (YMSM) were at a potential high risk of mpox infection due to their sexual activeness and the eased COVID-19 restrictions at the end of 2022. Objective This study aimed to investigate the behavioral intention of receiving mpox vaccination and undergoing mpox testing in 4 different scenarios and explore their associations with background and behavioral theory–related factors among Chinese YMSM. Methods An online cross-sectional survey was co

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Huang, Mei-Feng, Yu-Ping Chang, Chien-Wen Lin, and Cheng-Fang Yen. "Factors Related to Mpox-Vaccine Uptake among Men Who Have Sex with Men in Taiwan: Roles of Information Sources and Emotional Problems." Vaccines 12, no. 3 (2024): 332. http://dx.doi.org/10.3390/vaccines12030332.

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An mpox outbreak occurred suddenly and rapidly spread worldwide in 2022. Research has demonstrated a link between the sexual behavior of men who have sex with men (MSM) and the contraction of mpox. This study assessed the factors related to mpox-vaccine uptake among MSM in Taiwan, focusing on the roles of information sources and emotional problems. In total, 389 MSM participated in an online survey. Data on the participants’ vaccination statuses; anxiety symptoms, which were assessed using the State–Trait Anxiety Inventory; depressive symptoms, which were assessed using the Center for Epidemio

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8

Lopez, Cristina, Rafael Sanchez-Sanchez, Diana Corona, et al. "A Fatal Case of Monkeypox-Associated Encephalitis in a Non–HIV-Infected Patient." Critical Care Explorations 7, no. 6 (2025): e1272. https://doi.org/10.1097/cce.0000000000001272.

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BACKGROUND: Mpox, formerly known as monkeypox, is an infectious disease caused by the mpox virus. Systemic involvement is rare and mpox-associated meningoencephalitis is an uncommon clinical presentation. Because mpox-associated meningoencephalitis is characterized by nonspecific clinical and incidental imaging findings, the disease is difficult to diagnose. CASE SUMMARY: We present a case of fatal mpox-associated meningoencephalitis with negative polymerase chain reaction in cerebrospinal fluid (CSF) diagnosed at autopsy. A young immunocompetent patient with no significant medical history ini

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Turpin, Rodman E., CJ Mandell, Aaron D. Camp, et al. "Monkeypox-Related Stigma and Vaccine Challenges as a Barrier to HIV Pre-Exposure Prophylaxis among Black Sexual Minority Men." International Journal of Environmental Research and Public Health 20, no. 14 (2023): 6324. http://dx.doi.org/10.3390/ijerph20146324.

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Background: The U.S. monkeypox (mpox) outbreak of 2022 was a unique emergent public health crisis disproportionately affecting Black sexual minority men (BSMM). Similar to other stigmas, mpox-related stigma may have adverse effects on BSMM, including deterring HIV prevention such as PrEP. Methods: Our study investigated the experiences and perceptions of BSMM related to mpox, including mpox-associated stigma, and PrEP engagement among BSMM. We conducted qualitative interviews of 24 BSMM attending HIV prevention-related events in the greater D.C. Metropolitan area. In-depth interviews were cond

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10

Chen, Yuanyi, Yuwei Li, Leiwen Fu, et al. "Knowledge of Human Mpox (Monkeypox) and Attitude towards Mpox Vaccination among Male Sex Workers in China: A Cross-Sectional Study." Vaccines 11, no. 2 (2023): 285. http://dx.doi.org/10.3390/vaccines11020285.

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Background: Re-emerging human mpox (previously known as monkeypox) is spreading around the world. According to existing studies, the current mpox pandemic mainly affects men who have sex with men (MSM), including male sex workers (MSW). Our study aimed to assess mpox knowledge and attitude towards mpox vaccination among MSW in China. Methods: A web-based, cross-sectional survey was conducted in August 2022. We collected participants’ socio-demographic characteristics and knowledge with 15 knowledge items related to mpox. Modified Bloom’s cut-off points of 80% (total score > 12) was used to

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Breban, Romulus. "The Peculiar Emergence of Mpox (Monkeypox): Directions for the Search for the Natural Reservoir and Vaccination Strategies." Vaccines 12, no. 10 (2024): 1142. http://dx.doi.org/10.3390/vaccines12101142.

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Background/Objectives: Mpox (monkeypox) is a zoonosis with origins in a currently unknown African reservoir. The first epidemiological accounts of mpox date back to the early 1980s, yet mpox only emerged as a pandemic threat in 2022–2023, more than 40 years later. This scenario is very different from those of other emerging diseases such as HIV and SARS, which immediately spread globally, in fully susceptible populations, starting from patients zero. Methods: We use mathematical modeling to illustrate the dynamics of mpox herd immunity in small communities in touch with the mpox natural reserv

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Toumasis, P., V. Paparizos, and G. Vrioni. "A comprehensive review of monkeypox (mpox) on the occasion of the ongoing multicountry outbreak of the disease." ACTA MICROBIOLOGICA HELLENICA 67, no. 4 (2023): 269–77. https://doi.org/10.5281/zenodo.10077693.

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The ongoing recent outbreak of mpox, extending to both endemic and non endemic regions, has emerged as a growing international public health threat. The purpose of this review is to highlight the basics of the disease. Mpox is a zoonotic infectious disease, caused by MPV, a DNA virus in the genus Orthopoxvirus. There are two possible means of mpox transmission: animal-to-human and human-to-human transmission. In this epidemic, mpox is predominantly affecting men who have sex with men. The early symptoms and signs of mpox are nonspecific but the subsequent evolution of the skin lesions is chara

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O’Connor, Lauren F., Morgan Byrne, Anuja Baskaran, et al. "Characterizing Indicators of Engagement in HIV-Associated Healthcare and Clinical Outcomes among People with HIV and Mpox in Washington, DC: A Nested Case-Control Study of the DC Cohort." Pathogens 13, no. 2 (2024): 117. http://dx.doi.org/10.3390/pathogens13020117.

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The high proportion of people with HIV (PWH) in the 2022–2023 mpox outbreak has raised questions surrounding the association between HIV and mpox. The objectives of this study were to evaluate the association between engagement in HIV-associated healthcare and mpox diagnosis, as well as to characterize cases of mpox among PWH. The DC Cohort is a longitudinal cohort of PWH in Washington, DC. We conducted a 5:1 (controls:cases) nested case-cohort study on male participants, matching age and care site. Cases were participants with an identified mpox diagnosis. Conditional logistic regression was

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Yadav, Rajesh, Anis Ahmad Chaudhary, Ujjwal Srivastava, et al. "Mpox 2022 to 2025 Update: A Comprehensive Review on Its Complications, Transmission, Diagnosis, and Treatment." Viruses 17, no. 6 (2025): 753. https://doi.org/10.3390/v17060753.

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Monkeypox virus (Mpox virus) is a zoonotic orthopoxvirus that has gained increased global attention due to recent outbreaks. The current review reports the latest update of Mpox cases from 25 February 2022 to 29 April 2025. It also evaluates the possible major complications in human life caused by Mpox. In early 2022, more than 40 countries reported Mpox outbreaks. As of 12 June 2024, the global case count for the 2022–2023 Mpox outbreak was 97,281 confirmed cases, in 118 countries. The World Health Organization (WHO) declared the Mpox virus, a zoonotic disease, a public health emergency of in

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Torres, Thiago Silva, Mayara Secco Torres Silva, Carolina Coutinho, et al. "Evaluation of Mpox Knowledge, Stigma, and Willingness to Vaccinate for Mpox: Cross-Sectional Web-Based Survey Among Sexual and Gender Minorities." JMIR Public Health and Surveillance 9 (July 17, 2023): e46489. http://dx.doi.org/10.2196/46489.

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Background The 2022 multicountry mpox outbreak positioned the condition as a public health emergency of international concern. By May 2023, Brazil ranked second globally in the cumulative number of mpox cases and deaths. The higher incidence of mpox among gay and other men who have sex with men in the current mpox outbreak deepens the stigma and discrimination against sexual and gender minorities (SGM). This might worsen the structural barriers impacting access to health services, which ultimately leads to undertesting and underreporting of cases. There are no data available on mpox knowledge

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Fu, Leiwen, Yinghui Sun, Yuwei Li, et al. "Perception of and Vaccine Readiness towards Mpox among Men Who Have Sex with Men Living with HIV in China: A Cross-Sectional Study." Vaccines 11, no. 3 (2023): 528. http://dx.doi.org/10.3390/vaccines11030528.

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Background: Men who have sex with men (MSM) living with HIV make up the majority of cases in the current Mpox outbreak. We aimed to investigate the perception of and vaccine readiness towards Mpox among MSM living with HIV in China. Methods: This cross-sectional online study was conducted from 10 August to 9 September 2022. Participants responded to survey questions about their socio-demographic information, HIV status, sexual behaviors, knowledge of Mpox, and attitudes towards Mpox vaccines. Results: A total of 577 MSM living with HIV participated in the study. A total of 37.6% expressed conc

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Oktaviani, Yoneta, and Nur Medina Ridha. "LITERATUR REVIEW JURNAL: ANALISIS TENTANG PENYAKIT MENULAR CACAR MONYET (MPOX) YANG MENYERANG KALANGAN ANAK-ANAK." Jurnal Kesehatan Husada Gemilang 8, no. 1 (2025): 37–41. https://doi.org/10.61129/jkhg.v8i1.110.

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Monkey pox (monkeypox) is a viral infectious disease caused by viruses in the genus orthopoxvirus. Mpox cases have also been reported in children and adolescents. During 1970-2021, Mpox cases in Central Africa were mostly (54%-90%) reported in children. This journal review aims to find out how the Mpox disease is transmitted to attack humans. The method used is descriptive analysis (systematic literature review) by collecting several journals about MPox infectious diseases. From the results obtained, the analysis shows that the infectious disease monkey pox (Mpox) which attacks humans can be t

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Omame, Andrew, Sarafa A. Iyaniwura, Qing Han, et al. "Dynamics of Mpox in an HIV endemic community: A mathematical modelling approach." Mathematical Biosciences and Engineering 22, no. 2 (2025): 225–59. https://doi.org/10.3934/mbe.2025010.

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<p>During the 2022 monkeypox (Mpox) outbreak in non-endemic countries, sexual transmission was identified as the dominant mode of transmission, and particularly affected the community of men who have sex with men (MSM). This community experienced the highest incidence of Mpox cases, exacerbating the public health burden they already face due to the disproportionate impact of HIV. Given the simultaneous spread of HIV and Mpox within the MSM community, it is crucial to understand how these diseases interact. Specifically, since HIV is endemic within this population, understanding its influ

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Yan, XiangYu, Zhuo Li, Chunxia Cao, et al. "Characteristics, Influence, Prevention, and Control Measures of the Mpox Infodemic: Scoping Review of Infodemiology Studies." Journal of Medical Internet Research 26 (August 30, 2024): e54874. http://dx.doi.org/10.2196/54874.

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Background The mpox pandemic has caused widespread public concern around the world. The spread of misinformation through the internet and social media could lead to an infodemic that poses challenges to mpox control. Objective This review aims to summarize mpox-related infodemiology studies to determine the characteristics, influence, prevention, and control measures of the mpox infodemic and propose prospects for future research. Methods The scoping review was conducted based on a structured 5-step methodological framework. A comprehensive search for mpox-related infodemiology studies was per

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Walsh-Buhi, Margaret L., Rebecca F. Houghton, Danny Valdez, and Eric R. Walsh-Buhi. "A theory-based assessment of mpox: Findings from a nationally representative survey of U.S. adults." PLOS ONE 19, no. 3 (2024): e0299599. http://dx.doi.org/10.1371/journal.pone.0299599.

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The purpose of this research was to examine individual differences related to fear of, perceived susceptibility to, and perceived severity of mpox as well as mpox knowledge, fear, perceived susceptibility, and perceived severity as predictors of vaccine intention in a national survey of U.S. adults (aged ≥18 years). Address-based sampling (ABS) methods were used to ensure full coverage of all households in the nation, reflecting the 2021 March Supplement of the Current Population Survey. Internet-based surveys were self-administered by Ipsos between September 16–26, 2022. N = 1018 participants

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Alqahtani, Rubayyi T., Salihu S. Musa, and Mustafa Inc. "Modeling the role of public health intervention measures in halting the transmission of monkeypox virus." AIMS Mathematics 8, no. 6 (2023): 14142–66. http://dx.doi.org/10.3934/math.2023723.

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<abstract><p>Monkeypox (mpox), a zoonotic viral disease caused by the monkeypox virus (mpoxv), is endemic in many countries in West Africa and is sometimes exported to other parts of the world. The recent outbreak of mpoxv in humans, in endemic and non-endemic countries, has created substantial public health concern worldwide. This research uses a mechanistic model to study the transmission dynamics of mpoxv epidemics in the USA. Our model describes the interaction between different categories of individuals represent various infection phases and hospitalization processes. The mode

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Atkins, Kaitlyn, Thomas Carpino, Amrita Rao, et al. "Suspected Mpox Symptoms and Testing in Men Who Have Sex With Men in the United States: Cross-Sectional Study." JMIR Public Health and Surveillance 11 (January 16, 2025): e57399-e57399. https://doi.org/10.2196/57399.

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Abstract Background The 2022 mpox outbreak in the United States disproportionately affected gay, bisexual, and other men who have sex with men (GBMSM). Uptake of mpox testing may be related to symptomology, sociodemographic characteristics, and behavioral characteristics. Objective This study aimed to describe suspected mpox symptoms and testing uptake among a sample of GBMSM recruited via the internet in the United States in August 2022. Methods We conducted a rapid internet-based mpox survey from August 5 to 15, 2022, among cisgender men 15 years and older who had previously participated in

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Islam, Md Rabiul, Md Anamul Haque, Bulbul Ahamed, et al. "Assessment of vaccine perception and vaccination intention of Mpox infection among the adult males in Bangladesh: A cross-sectional study findings." PLOS ONE 18, no. 6 (2023): e0286322. http://dx.doi.org/10.1371/journal.pone.0286322.

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Background Mpox (monkeypox) infection has become a global concern for healthcare authorities after spreading in multiple non-endemic countries. Following the sudden multi-country outbreak of Mpox, the World Health Organization (WHO) declared a public health emergency of international concern. We do not have any vaccines approved for the prevention of Mpox infection. Therefore, international healthcare authorities endorsed smallpox vaccines for the prevention of Mpox disease. Here we intended to perform this cross-sectional study among the adult males in Bangladesh to assess the Mpox vaccine pe

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Zheng, Min, Min Du, Guanghong Yang, et al. "Mpox Vaccination Hesitancy and Its Associated Factors among Men Who Have Sex with Men in China: A National Observational Study." Vaccines 11, no. 9 (2023): 1432. http://dx.doi.org/10.3390/vaccines11091432.

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More than 400 confirmed mpox cases have been reported in China. The mpox vaccination is crucial to mitigate mpox transmission, especially for at-risk populations. This study aimed to determine mpox vaccination hesitancy and its associated factors in Chinese men who have sex with men (MSM). This nationwide cross-sectional study was conducted among 7538 Chinese MSM in 27 MSM social organizations from 21 provinces, municipalities, and autonomous regions of China from 31 July to 4 August 2023. Of them, the rate of mpox vaccination hesitancy was 5.59% (421/7538). The most common reason for mpox vac

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Yinka-Ogunleye, Adesola, Mahmood Dalhat, Afolabi Akinpelu, et al. "Mpox (monkeypox) risk and mortality associated with HIV infection: a national case–control study in Nigeria." BMJ Global Health 8, no. 11 (2023): e013126. http://dx.doi.org/10.1136/bmjgh-2023-013126.

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IntroductionRecent outbreaks of mpox are characterised by changes in the natural history of the disease, the demographic and clinical characteristics of the cases, and widening geographical distribution. We investigated the role of HIV and other sexually transmitted infections (STIs) coinfection among cases in the re-emergence of mpox to inform national and global response.MethodsWe conducted a national descriptive and case–control study on cases in the 2017–2019 Nigerian mpox outbreak. Mpox cases were age, sex and geographical area matched each with two randomly selected controls from a repre

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Banna, Md Hasan Al, Abdul-Aziz Seidu, Trisha Mallick, et al. "Knowledge regarding human monkeypox among a sample of undergraduate and post-graduate students from selected tertiary institutions in Bangladesh: An online-based cross-sectional study." PLOS ONE 19, no. 12 (2024): e0315677. https://doi.org/10.1371/journal.pone.0315677.

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Background The recent human monkeypox (mpox) outbreak in 2022 has become a serious concern due to its rapid expansion to various non-endemic countries. There is limited information about the knowledge regarding mpox among the Bangladeshi population. Therefore, this study’s objectives were to: (i) determine the level of knowledge regarding mpox among undergraduate and post-graduate students in Bangladesh, and (ii) assess the determinants of knowledge regarding mpox among the study sample. Methods An online-based cross-sectional study was conducted among 879 tertiary-level students from selected

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Gao, Liping, Qi Shi, Xiaoping Dong, Miao Wang, Zhiguo Liu, and Zhenjun Li. "Mpox, Caused by the MPXV of the Clade IIb Lineage, Goes Global." Tropical Medicine and Infectious Disease 8, no. 2 (2023): 76. http://dx.doi.org/10.3390/tropicalmed8020076.

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Mpox is a great public health concern worldwide currently; thus, a global primary epidemiological analysis of mpox and a phylogenetic analysis of currently circulating MPXV strains based on open-source data is necessary. A total of 83,419 confirmed cases with 72 deaths were reported from 7 May to 23 December 2022, representing an ongoing increasing trend. Mpox was largely restricted to being endemic in children in West Africa (WA) before 2022, and it mainly spread from animals to humans. Our analysis highlights that mpox has not only spread across regions within Africa but has also led to most

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Zong, Yuan, Koju Kamoi, Jing Zhang, Mingming Yang, and Kyoko Ohno-Matsui. "Mpox (Monkeypox) and the Eye: Ocular Manifestation, Diagnosis, Treatment, and Vaccination." Viruses 15, no. 3 (2023): 616. http://dx.doi.org/10.3390/v15030616.

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At present, the world is at the tipping point of the outbreak of mpox. The World Health Organization has declared the current mpox outbreak a ‘public health emergency of international concern.’ Mpox has been shown to be associated with several ocular manifestations. Given the current state of the mpox outbreak, healthcare providers, particularly ophthalmologists, need to be aware of these ophthalmic symptoms and how to manage them. In this review, we highlight current knowledge on the ocular symptoms of mpox virus (MPXV) infections and how to detect them. In addition, we summarize the treatmen

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Schwartz, David A., and Phillip R. Pittman. "Mpox (Monkeypox) in Pregnancy: Viral Clade Differences and Their Associations with Varying Obstetrical and Fetal Outcomes." Viruses 15, no. 8 (2023): 1649. http://dx.doi.org/10.3390/v15081649.

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In African countries where mpox (monkeypox) is endemic, infection is caused by two genetically related clades—Clade I (formerly Congo Basin), and Clade IIa (formerly West Africa), both of which are potentially life-threatening infections. Prior to the 2022–2023 global outbreak, mpox infections among pregnant women caused by Clade I were reported to have a 75% perinatal case fatality rate in the Democratic Republic of Congo, including the only documented case of placental infection and stillbirth from the Congenital Mpox Syndrome, and the Clade IIa mpox infection was associated with stillbirths

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Raccagni, Angelo Roberto, Nicola Gianotti, Matteo Moro, et al. "Mpox Virus: Control of In-Hospital Occupational Transmission Experience from a Tertiary Level Hospital in Milan, Italy." Life 13, no. 8 (2023): 1705. http://dx.doi.org/10.3390/life13081705.

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Mpox has caused a global outbreak since May 2022, particularly affecting people belonging to key populations, but cases among healthcare providers have been reported. The aim of this work is to present the experience of the Infectious Diseases Unit of San Raffaele Scientific Institute, Milan, Italy with respect to infection control and prevention of mpox occupational transmission. Between May–November 2022, 140 individuals were diagnosed with mpox and six required hospitalization. Overall, 12 medical doctors and 22 nurses provided care to people with mpox. A hospital policy aimed at controllin

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Hetta, Helal F., Ahmad A. Alharbi, Shumukh M. Alsharif, et al. "Mpox Virus Infection and Vaccination: Immunopathogenesis and Exploring the Link to Neuropsychiatric Manifestations." Immuno 4, no. 4 (2024): 578–600. https://doi.org/10.3390/immuno4040034.

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Background and Aim: Monkeypox (Mpox) is a viral disease mainly found in central and western Africa, with symptoms similar to variola virus (smallpox) but distinguished by the early lymph node swelling specific to Mpox. This review summarizes the neuropsychiatric manifestations of Mpox infection and vaccination, along with management approaches. Method: We searched different databases such as PubMed, Scopus, WoS, and Google Scholar about the neuropsychiatric manifestations of Mpox disease and the associated strategies of management. Results and conclusions: Mpox can cause a wide range of neurol

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Riad, Abanoub, Nadzeya Rybakova, Nadzeya Dubatouka, et al. "Belarusian Healthcare Professionals’ Views on Monkeypox and Vaccine Hesitancy." Vaccines 11, no. 8 (2023): 1368. http://dx.doi.org/10.3390/vaccines11081368.

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Background: Despite the low transmission risk of Monkeypox (mpox) in Belarus, this study is vital as it contributes to our understanding of vaccine hesitancy among healthcare professionals (HCPs). It aims to assess vaccination perceptions and evaluate the willingness to pay for the vaccine among Belarusian HCPs, thereby enhancing pandemic preparedness. Methods: in October 2022, a cross-sectional survey-based study was conducted among Belarusian HCPs using a self-administered questionnaire (SAQ). Invitations were disseminated via social media platforms using a snowball sampling method. The SAQ

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Jarrell, Lynda, and Kashiris Perryman. "Mpox (monkeypox)." Nurse Practitioner 48, no. 4 (2023): 13–20. http://dx.doi.org/10.1097/01.npr.0000000000000025.

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Fiederer, Carolina, and Saskia Schnabl-Scheu. "Mpox (Affenpocken)." Die Dermatologie 74, no. 2 (2023): 121. http://dx.doi.org/10.1007/s00105-022-05088-0.

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Nilasari, Hanny, Eliza Miranda, Melani Marissa, et al. "Epidemiology and Clinical Features of Mpox in Jakarta, Indonesia, August 2022–December 2023." Vaccines 13, no. 3 (2025): 210. https://doi.org/10.3390/vaccines13030210.

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Background/Objective: This study explores the epidemiology and clinical features of re-emerging mpox in Jakarta, Indonesia. Methods: This study used a retrospective study design to describe the epidemiological data, clinical features, and mortality of mpox patients from August 2022 to December 2023. In addition, this study also aims to identify the differences in both the epidemiology and clinical features of mpox in people living with HIV (PLHIV) and in non-HIV patients (non-PLHIV). Results: Our study shows that, as of the end of December 2023, 59 mpox cases were treated in Jakarta. All of th

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Ridho, Fiki Muhammad, Anisa Dias Nur'aini, Hamnah Al Atsariyah, Andika Julyanto Syachputra, Wisnu Eka Wardana, and Andang Nurhuda. "La curcumina y sus derivados como posibles candidatos antivirales contra la viruela del mono (mpox): una revisión de estudios computacionales." Ars Pharmaceutica (Internet) 66, no. 2 (2025): 225–32. https://doi.org/10.30827/ars.v66i2.32423.

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Introduction: Monkeypox (mpox) is an infectious disease caused by the mpox virus that is of global health concern because the outbreak, as of May 2023, has affected more than 80,000 people in hundreds of countries. Currently, there is no specific treatment, including antivirals, for mpox patients. Exploration of active compounds for mpox continues, one of which is curcumin and its derivatives. Curcumin is a polyphenol compound predominantly found in turmeric which has been documented to have antiviral effects. Therefore, this study aims to explore studies investigating the potential of curcumi

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Adamo, Sarah, Yu Gao, Curtis Cai, et al. "Identity of virus-specific and cross-reactive T cell memory to mpox." Journal of Immunology 210, no. 1_Supplement (2023): 59.47. http://dx.doi.org/10.4049/jimmunol.210.supp.59.47.

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Abstract The unprecedented spread of mpox (previously known as monkeypox) in several countries worldwide has led the WHO to declare the mpox outbreak a global health emergency in 2022. T cell responses are likely to play a central role in the resolution of the mpox infection. However, the prevalence and phenotype of mpox-specific T cells have not been investigated in detail, and the extent of cross-reactive immunological memory following previous smallpox vaccination is not known. Here, we assessed T cell responses to mpox infection in n=22 convalescent patients and n=53 healthy blood donors o

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Ramírez-Soto, Max Carlos, and Hugo Arroyo-Hernández. "High Global Health Security Index is a determinant of early detection and response to monkeypox: A cross-sectional study." PLOS ONE 19, no. 7 (2024): e0307503. http://dx.doi.org/10.1371/journal.pone.0307503.

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Introduction Recent outbreaks of monkeypox (Mpox) have occurred in countries outside of Africa, with large numbers of cases spreading rapidly to almost every continent. We aimed to analyze the correlation between the Global Health Security (GHS) Index (categories and indicators) and the Mpox case rate in different regions and globally. Methods In this cross-sectional study, we used data from Mpox cases from the WHO, and the GHS categories and indicators for detection, prevention, reporting, health system, rapid response, international norms compliance, and risk environment. Outcome measures we

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Mahameed, Haneen, Kholoud Al-Mahzoum, Lana A. AlRaie, et al. "Previous Vaccination History and Psychological Factors as Significant Predictors of Willingness to Receive Mpox Vaccination and a Favorable Attitude towards Compulsory Vaccination." Vaccines 11, no. 5 (2023): 897. http://dx.doi.org/10.3390/vaccines11050897.

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During the ongoing multi-country monkeypox (Mpox) outbreak, healthcare workers (HCWs) have represented a key group in mitigating disease spread. The current study aimed to evaluate the attitude of nurses and physicians in Jordan towards Mpox vaccination, as well as their attitude towards compulsory vaccination against coronavirus disease 2019 (COVID-19), influenza, and Mpox. An online survey was distributed in January 2023 based on the previously validated 5C scale for psychological determinants of vaccination. Previous vaccination behavior was assessed by inquiring about the history of gettin

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Malaeb, Diana, Malik Sallam, Nesreen A. Salim, et al. "Knowledge, Attitude and Conspiracy Beliefs of Healthcare Workers in Lebanon towards Monkeypox." Tropical Medicine and Infectious Disease 8, no. 2 (2023): 81. http://dx.doi.org/10.3390/tropicalmed8020081.

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The emergence of a monkeypox (MPOX) outbreak in 2022 represented the most recent recognizable public health emergency at a global level. Improving knowledge and attitude towards MPOX, particularly among healthcare workers (HCWs), can be a valuable approach in public health preventive efforts aiming to halt MPOX virus spread. The aim of the current study was to evaluate the knowledge and attitude of HCWs in Lebanon towards MPOX and to assess their conspiratorial attitude towards emerging virus infections (EVIs). The current study was based on a cross-sectional online survey distributed via Goog

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Malik, Waleed, Justin Chan, Simon Dosovitz, Clyde Gilmore, and Jeanne Cosico. "Mpox exposure on a congregate inpatient psychiatry unit: Description of the investigation and outcomes—New York City, 2022." Antimicrobial Stewardship & Healthcare Epidemiology 3, S2 (2023): s67. http://dx.doi.org/10.1017/ash.2023.315.

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Background: In May 2022, New York City (NYC) experienced a large outbreak of human mpox (clade IIb). Data on mpox transmission following exposure in healthcare facilities in nonendemic settings are limited. Because mpox was previously not seen in NYC, our healthcare staff may not always recognize a suspected case and therefore may neglect to implement timely infection prevention and control measures, leading to infectious exposures. The risk of transmission from unrecognized mpox may be higher in inpatient psychiatric units where direct physical contact is more common in the setting of common

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Ikram, Muhammad Tabish, Faisal Hassan, Muhammad Irfan, Faryal Miraj, Yasir Ali, and Shah Fiaz. "Crossing the Borders – Monkey Pox in an HIV-Positive Pakistani Man Travelling from the Kingdom of Saudi Arabia; A Case Report." Journal of Gandhara Medical and Dental Science 10, no. 4 (2023): 89–91. http://dx.doi.org/10.37762/jgmds.10-4.562.

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Monkeypox, now called Mpox, was previously endemic to central and western Africa; however, a recent outbreak of Mpox was noticed outside its traditional endemic regions. We report a case of Mpox in a 33-year-old HIV-positive gentleman, the fourth case in Pakistan and the first in Khyber Pakhtunkhwa (KP). Risk factors like age, gender, and unsafe and risky sexual behavior put this patient at risk of Mpox.

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Lindner, Martin S., Kevin Brick, Nicholas Noll, et al. "873. Detection of Monkeypox Virus Using Microbial Cell-free DNA: Demonstrating the Potential of Agnostic Sequencing for Real Time Identification of an Emerging Pathogen." Open Forum Infectious Diseases 10, Supplement_2 (2023). http://dx.doi.org/10.1093/ofid/ofad500.918.

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Abstract Background The 2022 global monkeypox (mpox) outbreak has resulted in &gt;86,000 cases worldwide. Mpox virus (mpoxv) PCR has failed for some divergent strains. Additionally, currently recommended testing requires a swab of lesions, which arise well after infection and may be unrecognized, especially in atypical disease. We present mpoxv detections using plasma microbial cell-free DNA (mcfDNA) sequencing. Methods We characterized 13 case-patients in whom plasma mcfDNA sequencing, by the Karius CLIA certified/CAP accredited laboratory, detected and quantified the concentration of mpo

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Zebardast, Arghavan, Tayebeh Latifi, Nazanin-Zahra Shafiei-Jandaghi, Mehdi Gholami Barzoki, and Somayeh Shatizadeh Malekshahi. "Plausible reasons for the resurgence of Mpox (formerly Monkeypox): an overview." Tropical Diseases, Travel Medicine and Vaccines 9, no. 1 (2023). http://dx.doi.org/10.1186/s40794-023-00209-6.

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AbstractPoxviruses are large and diversified viruses that cause an emerging zoonotic disease known as monkeypox (mpox). In the past, mpox predominated primarily in the rural rainforests of Central and West Africa. Recently, the exportation of mpoxv from Africa to other continents has been progressively reported. However, the lack of travel history to Africa in most of the currently reported cases in 2022 promotes the sign of changing epidemiology of this disease. Concerns over the geographic distribution and continued resurgence of mpox is growing. In this review, we addressed the geographic d

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Moretti, Marco, Annelies Meuwissen, Antonio M. Rezende, et al. "Breakthrough Mpox outbreak investigation, the delicate balance between host immune response and viral immune escape." Sexually Transmitted Diseases, April 19, 2024. http://dx.doi.org/10.1097/olq.0000000000001974.

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ABSTRACT Background Limited data is available on Mpox breakthrough infections. Purpose Investigate a Mpox breakthrough outbreak in three vaccinated individuals. Methods Study participants provided informed consent. Serology testing was performed in one involved individual (ID-1) using an in-house assay detecting anti-orthopoxvirus IgG. Whole genome sequencing (WGS) was carried out and compared to the reference sequence ON563414.3 (https://www.ncbi.nlm.nih.gov/nuccore/ON563414.3/). Results Three individuals vaccinated with modified vaccinia Ankara–Bavaria Nordic contracted Mpox following one se

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Sönmez, İbrahim, Héctor Martínez Riveros, Cinta Folch, et al. "Egocentric sexual network analysis among gay and bisexual men who have sex with men with and without mpox infection." Sexually Transmitted Infections, September 13, 2023, sextrans—2023–055901. http://dx.doi.org/10.1136/sextrans-2023-055901.

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ObjectivesRecent outbreaks of the mpox (monkeypox) virus have been detected in dense sexual networks of gay and bisexual men who have sex with men (GBMSM). The objective of this study is to describe and compare the epidemiological and behavioural characteristics, as well as the sexual networks, of GBMSM diagnosed with mild mpox in Spain.MethodsA prospective case–control study was conducted in Spain from July 2022 to February 2023. The study targeted a key population of GBMSM aged 18 years or older. Study participants were categorised into cases, those who were diagnosed with mpox virus infecti

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"Mpox." Pediatric Emergency Care 39, no. 11 (2023): 890–91. http://dx.doi.org/10.1097/01.pec.0000995496.96949.81.

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Robin, Alexandre, Yasmine Abi Aad, Nadia Valin, et al. "Du Mpox endémique au Mpox pandémique." La Revue de Médecine Interne, May 2025. https://doi.org/10.1016/j.revmed.2025.05.008.

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Yue, Yubiao, Minghua Jiang, Xinyue Zhang, et al. "Mpox-AISM: AI-Mediated Super Monitoring for Mpox and Like-Mpox." iScience, April 2024, 109766. http://dx.doi.org/10.1016/j.isci.2024.109766.

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Croasdale, Christopher R., Eric Weinlander, and Thomas G. Boyce. "Mpox Keratitis: A Case Report and Review." Cornea, July 5, 2024. http://dx.doi.org/10.1097/ico.0000000000003614.

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Purpose: Mpox is a rare infectious disease. Lack of knowledge among eye care professionals regarding mpox keratitis greatly reduces the likelihood of diagnosis and effective management. This report and review seek to increase the knowledge of mpox keratitis among eye care professionals. Methods: We report a patient with mpox keratitis who underwent successful penetrating keratoplasty, with 20 years of follow-up. A systematic literature search and review of cases of mpox keratitis from 1970 to 2024 was performed. Results: A total of 24 articles and 2 abstracts reporting 35 cases of mpox keratit

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