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Journal articles on the topic 'MPS-system'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Saulys, A. C., A. Etkin, K. J. Foley, et al. "MPS data-acquisition software system." Computer Physics Communications 57, no. 1-3 (1989): 353–57. http://dx.doi.org/10.1016/0010-4655(89)90242-7.

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2

Šarga, Patrik, and Tomáš Záboly. "MODERNIZATION OF THE TRANSPORT SYSTEM CONTROL OF THE PRODUCTION SYSTEM." TECHNICAL SCIENCES AND TECHNOLOGIES, no. 4(18) (2019): 141–47. http://dx.doi.org/10.25140/2411-5363-2019-4(18)-141-147.

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Urgency of the research. Nowadays, it is crucial to keep up with modern technologies. Therefore, this work aims to modernize the production system Festo MPS 500. Thanks to this, it will be possible to apply to the system technologies meeting the latest trends in Industry 4.0. The MPS 500 system prepared in this way can be used to research new trends in accordance with Industry 4.0. The modernized MPS 500 system will also find use in the education of students in the field of automation and mechatronics so that they are sufficiently prepared for practice. Target setting. The goal of the research

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3

Kataraki, Kirankumar V., and Satyadhyan Chickerur. "A Performance Study of Moving Particle Semi-Implicit Method for Incompressible Fluid Flow on GPU." International Journal of Distributed Systems and Technologies 11, no. 1 (2020): 83–94. http://dx.doi.org/10.4018/ijdst.2020010107.

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The aim of moving particle semi-implicit (MPS) is to simulate the incompressible flow of fluids in free surface. MPS, when implemented, consumes a lot of time and thus, needs a very powerful computing system. Instead of using parallel computing system, the performance level of the MPS model can be improved by using graphics processing units (GPUs). The aim is to have a computing system that is capable of performing at high levels thereby enhancing the speed of processing the numerical computations required in MPS. The primary aim of the study is to build a GPU-accelerated MPS model using CUDA

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4

Lin, Yi-Kuei, and John Yuan. "A New Algorithm to Generate d-Minimal Paths in a Multistate Flow Network with Noninteger ARC Capacities." International Journal of Reliability, Quality and Safety Engineering 05, no. 03 (1998): 269–85. http://dx.doi.org/10.1142/s0218539398000248.

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This article is mainly to study the reliability evaluation in terms of MPs (minimal paths) for a multistate flow network G in which the capacities of each arc are real numbers. The transportation system from the source node s to the sink node t is one of such typical networks. Given the system demand d from s to t and MPs in advance, an algorithm is proposed first to find out all lower boundary points of level d (namely d-MPs here). The system reliability which is the probability that the system flow satisfies the demand d can be calculated in terms of such d-MPs. One example is presented to i

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Schindler, Stephanie M., Jonathan P. Little, and Andis Klegeris. "Microparticles: A New Perspective in Central Nervous System Disorders." BioMed Research International 2014 (2014): 1–17. http://dx.doi.org/10.1155/2014/756327.

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Microparticles (MPs) are a heterogeneous population of small cell-derived vesicles, ranging in size from 0.1 to 1 μm. They contain a variety of bioactive molecules, including proteins, biolipids, and nucleic acids, which can be transferred between cells without direct cell-to-cell contact. Consequently, MPs represent a novel form of intercellular communication, which could play a role in both physiological and pathological processes. Growing evidence indicates that circulating MPs contribute to the development of cancer, inflammation, and autoimmune and cardiovascular diseases. Most cell types

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Yuan, Fu-Zhen, Hu-Fei Wang, Jian Guan, et al. "Fabrication of Injectable Chitosan-Chondroitin Sulfate Hydrogel Embedding Kartogenin-Loaded Microspheres as an Ultrasound-Triggered Drug Delivery System for Cartilage Tissue Engineering." Pharmaceutics 13, no. 9 (2021): 1487. http://dx.doi.org/10.3390/pharmaceutics13091487.

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Ultrasound-responsive microspheres (MPs) derived from natural polysaccharides and injectable hydrogels have been widely investigated as a biocompatible, biodegradable, and controllable drug delivery system and cell scaffolds for tissue engineering. In this study, kartogenin (KGN) loaded poly (lactide-co-glycolic acid) (PLGA) MPs (MPs@KGN) were fabricated by premix membrane emulsification (PME) method which were sonicated by an ultrasound transducer. Furthermore, carboxymethyl chitosan-oxidized chondroitin sulfate (CMC-OCS) hydrogel were prepared via the Schiff’ base reaction-embedded MPs to pr

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Tulebayeva, Assel, Maira Sharipova, and Riza Boranbayeva. "Respiratory Dysfunction in Children and Adolescents with Mucopolysaccharidosis Types I, II, IVA, and VI." Diagnostics 10, no. 2 (2020): 63. http://dx.doi.org/10.3390/diagnostics10020063.

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Mucopolysaccharidosis (MPS) is a rare genetic disease involving active storage of glycosaminoglycans (GAGs). Accumulation of GAGs in the connective tissues of airways leads to progressive pulmonary dysfunction. Studies conducted in Taiwan revealed mainly restrictive pulmonary dysfunction, whereas the same studies in Egypt and California revealed obstructive pulmonary dysfunction. The contradictory results and lack of studies of respiratory system in patients with MPS in Asian populations are an indication to study pulmonary impairment in patients with MPS in Kazakhstan. The prospective study o

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Mingtao, Kang, Zhang Yuliang, Jin Dapeng, et al. "The machine protection system for CSNS." Radiation Detection Technology and Methods 5, no. 2 (2021): 273–79. http://dx.doi.org/10.1007/s41605-021-00239-8.

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Abstract Background The China Spallation Neutron Source (CSNS) accelerator consists of an 80 MeV H- LINAC, a 1.6 GeV rapid cycling synchrotron (RCS) and two beam transport lines. The uncontrolled beam may permanently damage the components or lead to very high residual radiation dose along the beam line. So the equipment protection must be deliberately designed and implemented. Purpose The machine protection system (MPS) protects components from being damaged by the beam. The response time requirement for the CSNS MPS is less than 20 ms, so the PLC (programmable logic controller) was adopted to

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9

Feng, Haibo, Xiaonong Yang, Linzi Zhang, et al. "Mannose-Modified Chitosan Poly(lactic-co-glycolic acid) Microspheres Act as a Mannose Receptor-Mediated Delivery System Enhancing the Immune Response." Polymers 13, no. 13 (2021): 2208. http://dx.doi.org/10.3390/polym13132208.

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The mannose receptor (MAN-R)-targeted delivery system is commonly used to deliver antigens to macrophages or immature dendritic cells (DCs) to promote the efficiency of antigen presentation. To maximize the enhancement effects of chitosan (CS) and induce an efficient humoral and cellular immune response against an antigen, we encapsulated ovalbumin (OVA) in poly(lactic-co-glycolic acid) (PLGA) microspheres (MPs) and conjugated it with MAN-modified CS to obtain MAN-R-targeting nano-MPs (MAN-CS-OVA-PLGA-MPs). The physicochemical properties, drug loading rate, and immunomodulation activity of MAN

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Kim, Keug Tae, and Sanghwa Park. "Enhancing Microplastics Removal from Wastewater Using Electro-Coagulation and Granule-Activated Carbon with Thermal Regeneration." Processes 9, no. 4 (2021): 617. http://dx.doi.org/10.3390/pr9040617.

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Discharge from sewage treatment plants (STPs) is a significant pathway of entry for microplastics (MPs) to the environment. Therefore, STPs should be considered as an important barrier to the distribution and circulation of MPs in the aquatic environment. In this study, the fate and material-specific properties of MPs were investigated in an STP-equipped and granule-activated carbon (GAC) tower with a thermal regeneration system. This system functioned with a tertiary treatment unit. The GAC with thermal regeneration removed 92.8% of MPs and was useful for removing MPs with a specific gravity

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11

O'Dowd, A. "Peer review system needs thorough evaluation, MPs hear." BMJ 342, may16 2 (2011): d3046. http://dx.doi.org/10.1136/bmj.d3046.

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12

Mishins, P. A., and S. C. Sarin. "Mathematical analysis of the MPS MX missile system." Applied Mathematical Modelling 9, no. 2 (1985): 139–42. http://dx.doi.org/10.1016/0307-904x(85)90126-x.

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13

Zhao, Xiang Yang, Xia Yuan, and Yun Lou. "Research and Design of a Novel Mobile Police Station." Advanced Materials Research 605-607 (December 2012): 341–45. http://dx.doi.org/10.4028/www.scientific.net/amr.605-607.341.

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By studying the design theory of the mobile police station (MPS), the dynamic model of the MPS basic computing has been built then a novel MPS is designed. This kind of MPS, which consists of battery, chassis, body and electrical system, uses electric vehicle as the carrier and in combination with police needs is equipped with a variety of police equipment to meet the needs of establishing a modern police. The vehicle performance test has been done. The results prove that the performance of the MPS has reached the technical level of the Ministry of Science and Technology, showing the vehicle d

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Park, Ki Ho, Leonardo Hernandez, Shi-Qing Cai, Yi Wang, and Federico Sesti. "A Family of K+ Channel Ancillary Subunits Regulate Taste Sensitivity in Caenorhabditis elegans." Journal of Biological Chemistry 280, no. 23 (2005): 21893–99. http://dx.doi.org/10.1074/jbc.m502732200.

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We have identified a family of ancillary subunits of K+ channels in Caenorhabditis elegans. MPS-1 and its related members MPS-2, MPS-3, and MPS-4 are detected in the nervous system of the nematode. Electrophysiological analysis in ASE neurons and mammalian cells and epigenetic inactivation by double-stranded RNA interference (RNAi) in vivo show that each MPS can associate with and functionally endow the voltage-gated K+ channel KVS-1. In the chemosensory neuron ADF, three different MPS subunits combine with KVS-1 to form both binary (MPS-1·KVS-1) and ternary (MPS-2·MPS-3·KVS-1) complexes. RNAi

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15

Hron, Gregor, Marietta Kollars, Heinz Weber, et al. "Tissue factor-positive microparticles: Cellular origin and association with coagulation activation in patients with colorectal cancer." Thrombosis and Haemostasis 97, no. 01 (2007): 119–23. http://dx.doi.org/10.1160/th06-03-0141.

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SummaryThe pathogenesis of hypercoagulability in cancer is not entirely understood. We hypothesized that in cancer patients circulating tissue factor-positive microparticles (TF+ MPs) are increased and associated with hemostatic system activation. In 20 patients with advanced colorectal cancer and in 20 age- and sex-matched controls, number and cellular origin of TF+ MPs were determined in plasma by flow cytometry. D-dimer was determined as an indicator of hemostatic system activation. Compared to controls, the median (interquartile range) number of TF+ MPs was two-fold higher in cancer patien

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Kokkinis, Georgios, Alexander Dangl, Franz Keplinger, and Ioanna Giouroudi. "Microfluidic Biosensing Method Using the Motion of Magnetic Microparticles." Key Engineering Materials 605 (April 2014): 348–51. http://dx.doi.org/10.4028/www.scientific.net/kem.605.348.

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In this paper a microfluidic biosensing method for detecting a bioanalyte using the motion of magnetic microparticles (MPs) is presented. The system consists of a microfluidic channel, in which the MPs are suspended and current carrying microconductors positioned underneath the channel. These microconductors are used in order to move the MPs from the inlet to the outlet of the channel. The MPs are functionalized by modifying their surface, thus enabling them to chemically bind to a specific (non-magnetic) bioanalyte. Once the MPs binds to the bioanalyte new compounds are formed (LMPs). These c

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17

François, Abel, and Julien Navarro. "Voters reward hard-working MPs: empirical evidence from the French legislative elections." European Political Science Review 11, no. 4 (2019): 469–83. http://dx.doi.org/10.1017/s1755773919000274.

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AbstractThis paper studies the relationship between incumbent MPs’ activities and their electoral fortune. We address this question in the context of the French political system characterized by an executive domination, a candidate-centered electoral system, and an electoral schedule maximizing the impact of the presidential elections. Given the contradictory influence of these three institutional features on the relationship between MPs’ activities and electoral results, the overall link can only be assessed empirically. We test the effects of several measurements of MPs’ activities on both t

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Park, Jun Woo, Su Jin Lee, Dae Youn Hwang, and Sungbaek Seo. "Recent Purification Technologies and Human Health Risk Assessment of Microplastics." Materials 13, no. 22 (2020): 5196. http://dx.doi.org/10.3390/ma13225196.

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Microplastic (MP)-based contaminants in the environment are pervasive, but standard technologies used for MP identification have not yet been reported. Human beings take up MPs from the environmental ecosystem through the food chain without any particular purification. MPs can penetrate into capillaries from the bloodstream, resulting in endocrine system disorders or toxicity. In this review, we introduced several technologies, such as filtration using membranes, biological degradation, electrocoagulation, and removal using nanoparticles, used for the purification of MPs or related contaminant

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19

Lin, Lee, Lo, et al. "An At-Risk Population Screening Program for Mucopolysaccharidoses by Measuring Urinary Glycosaminoglycans in Taiwan." Diagnostics 9, no. 4 (2019): 140. http://dx.doi.org/10.3390/diagnostics9040140.

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Background: The mucopolysaccharidoses (MPSs) are a group of rare lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) and which eventually cause progressive damage to various tissues and organs. We developed a feasible MPS screening algorithm and established a cross-specialty collaboration platform between medical geneticists and other medical specialists based on at-risk criteria to allow for an earlier confirmative diagnosis of MPS. Methods: Children (<19 years of age) with clinical signs and symptoms compatible with MPS were prospectively enrolled fr

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20

Zhang, Stephanie Y., and Gretchen J. Mahler. "Modelling Renal Filtration and Reabsorption Processes in a Human Glomerulus and Proximal Tubule Microphysiological System." Micromachines 12, no. 8 (2021): 983. http://dx.doi.org/10.3390/mi12080983.

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Kidney microphysiological systems (MPS) serve as potentially valuable preclinical instruments in probing mechanisms of renal clearance and osmoregulation. Current kidney MPS models target regions of the nephron, such as the glomerulus and proximal tubule (PCT), but fail to incorporate multiple filtration and absorption interfaces. Here, we describe a novel, partially open glomerulus and PCT microdevice that integrates filtration and absorption in a single MPS. The system equalizes pressure on each side of the PCT that operates with one side “closed” by recirculating into the bloodstream, and t

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21

Pierzynowska, Karolina, Lidia Gaffke, Zuzanna Cyske, et al. "Oxidative Stress in Mucopolysaccharidoses: Pharmacological Implications." Molecules 26, no. 18 (2021): 5616. http://dx.doi.org/10.3390/molecules26185616.

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Although mucopolysaccharidoses (MPS) are caused by mutations in genes coding for enzymes responsible for degradation of glycosaminoglycans, storage of these compounds is crucial but is not the only pathomechanism of these severe, inherited metabolic diseases. Among various factors and processes influencing the course of MPS, oxidative stress appears to be a major one. Oxidative imbalance, occurring in MPS and resulting in increased levels of reactive oxidative species, causes damage of various biomolecules, leading to worsening of symptoms, especially in the central nervous system (but not res

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Lee, Hyoung-Gon, Edmund W. Schuster, Stuart J. Allen, and Pinaki Kar. "The Open System for Master Production Scheduling." International Journal of Operations Research and Information Systems 1, no. 1 (2010): 1–15. http://dx.doi.org/10.4018/joris.2010101301.

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Commonly provided by ERP vendors, master production scheduling (MPS) systems often strive to meet the needs of a large user base while limiting software functionality. Subsequently, business process reengineering becomes the means for firms to adapt to MPS software packages. This article develops a flexible approach for MPS delivery as an alternative to packaged software. The article examines the general case of open system architecture to deliver a specific master scheduling model to end-users. The open system approach fulfills a goal to standardize and speed the process of modeling in practi

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Yang, Ming, Paul Kosterin, Brian M. Salzberg, Tatyana N. Milovanova, Veena M. Bhopale, and Stephen R. Thom. "Microparticles generated by decompression stress cause central nervous system injury manifested as neurohypophysial terminal action potential broadening." Journal of Applied Physiology 115, no. 10 (2013): 1481–86. http://dx.doi.org/10.1152/japplphysiol.00745.2013.

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The study goal was to use membrane voltage changes during neurohypophysial action potential (AP) propagation as an index of nerve function to evaluate the role that circulating microparticles (MPs) play in causing central nervous system injury in response to decompression stress in a murine model. Mice studied 1 h following decompression from 790 kPa air pressure for 2 h exhibit a 45% broadening of the neurohypophysial AP. Broadening did not occur if mice were injected with the MP lytic agent polyethylene glycol telomere B immediately after decompression, were rendered thrombocytopenic, or wer

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Amati, Andrea Marco, Simone Graf, Sabina Deutschmann, Nicolas Dolder, and Christoph von Ballmoos. "Current problems and future avenues in proteoliposome research." Biochemical Society Transactions 48, no. 4 (2020): 1473–92. http://dx.doi.org/10.1042/bst20190966.

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Membrane proteins (MPs) are the gatekeepers between different biological compartments separated by lipid bilayers. Being receptors, channels, transporters, or primary pumps, they fulfill a wide variety of cellular functions and their importance is reflected in the increasing number of drugs that target MPs. Functional studies of MPs within a native cellular context, however, is difficult due to the innate complexity of the densely packed membranes. Over the past decades, detergent-based extraction and purification of MPs and their reconstitution into lipid mimetic systems has been a very power

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Al-Jaibachi, Rana, Ross N. Cuthbert, and Amanda Callaghan. "Up and away: ontogenic transference as a pathway for aerial dispersal of microplastics." Biology Letters 14, no. 9 (2018): 20180479. http://dx.doi.org/10.1098/rsbl.2018.0479.

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Microplastics (MPs) are ubiquitous pollutants found in marine, freshwater and terrestrial ecosystems. With so many MPs in aquatic systems, it is inevitable that they will be ingested by aquatic organisms and be transferred up through the food chain. However, to date, no study has considered whether MPs can be transmitted by means of ontogenic transference, i.e. between life stages that use different habitats. Here, we determine whether fluorescent polystyrene beads could transfer between Culex mosquito life stages and, particularly, could move into the flying adult stage. We show for the first

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Vashakmadze, Nato D., Leyla S. Namazova-Baranova, Natalia V. Zhurkova, Ekaterina Yu Zakharova, Svetlana V. Mikhaylova, and Grigory V. Revunenkov. "Enzyme Replacement Therapy and Hematopoietic Stem Cell Transplantation Results in Patients with Hurler Syndrome: Clinical Cases." Current Pediatrics 18, no. 3 (2019): 196–202. http://dx.doi.org/10.15690/vsp.v18i3.2037.

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Mucopolysaccharidosis type I (MPS I) is the hereditary disease characterized with alpha-L-iduronidase activity decrease and further accumulation of heparan and dermatan sulfate in lysosomes. MPS I is rare autosomal recessive disorder with incidence of 0.5–4 cases on 100.000 live-birth infants. Meantime there two approaches in MPS I treatment: hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy (ERT). HSCT can be the best option for treatment of patients with severe MPS I (Hurler syndrome). Successful engraftment moderates such clinical signs as obstructive airway dise

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Peng, Yan, Hua-Yan Sun, Zong-Chun Wang, Xiao-Ding Xu, Jin-Chun Song, and Zuo-Jiong Gong. "Fabrication of Alginate/Calcium Carbonate Hybrid Microparticles for Synergistic Drug Delivery." Chemotherapy 61, no. 1 (2015): 32–40. http://dx.doi.org/10.1159/000440645.

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A hybrid drug delivery system coloaded with different drugs for synergistic drug delivery was developed. Alginate/calcium carbonate (CaCO3) hybrid microparticles (MPs) were fabricated via a facile coprecipitation method under mild conditions without using any organic solvent and surfactant. Due to the incorporation of negatively charged alginate chains onto the surface, the obtained hybrid MPs with spherical morphology showed good colloidal stability in an aqueous solution. An antitumor drug (doxorubicin, DOX) and a drug resistance reversal agent (verapamil, VP) were coloaded in the hybrid MPs

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Sánchez-Navarro, Jesús, Thor Fajardo, Stefania Zicca, Vicente Pallás, and Livia Stavolone. "Caulimoviridae Tubule-Guided Transport Is Dictated by Movement Protein Properties." Journal of Virology 84, no. 8 (2010): 4109–12. http://dx.doi.org/10.1128/jvi.02543-09.

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ABSTRACT Plant viruses move through plasmodesmata (PD) either as nucleoprotein complexes (NPCs) or as tubule-guided encapsidated particles with the help of movement proteins (MPs). To explore how and why MPs specialize in one mechanism or the other, we tested the exchangeability of MPs encoded by DNA and RNA virus genomes by means of an engineered alfalfa mosaic virus (AMV) system. We show that Caulimoviridae (DNA genome virus) MPs are competent for RNA virus particle transport but are unable to mediate NPC movement, and we discuss this restriction in terms of the evolution of DNA virus MPs as

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Halleaux, Douglas G., Jeffery M. Sussman, and Nilton O. Rennó. "The Michigan Prandtl System: An Instrument for Accurate Pressure Measurements in Convective Vortices." Journal of Atmospheric and Oceanic Technology 30, no. 10 (2013): 2426–33. http://dx.doi.org/10.1175/jtech-d-12-00246.1.

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Abstract This article describes a Prandtl tube system developed at the University of Michigan to measure the static pressure, the total (or stagnation) pressure, and the velocity in flows whose direction and intensity change rapidly. The ever-changing wind vectors in convective vortices are a challenge for making accurate measurements on them. Accurate measurements of the static pressure are particularly problematic because they require the sensor air intake to be aligned perpendicular to the wind direction. This article describes calibrations and tests of the Michigan Prandtl System (MPS) and

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Buarque Vieira-e-Silva, André Luiz, Caio José dos Santos Brito, Francisco Paulo Magalhães Simões, and Veronica Teichrieb. "A fluid simulation system based on the MPS method." Computer Physics Communications 258 (January 2021): 107572. http://dx.doi.org/10.1016/j.cpc.2020.107572.

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Tong, Yi Fei, Zhao Hui Tang, and Dong Mei Cao. "Research on Communication Design of Modular Production System." Applied Mechanics and Materials 339 (July 2013): 281–84. http://dx.doi.org/10.4028/www.scientific.net/amm.339.281.

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Touch screen is monitoring equipment used in industrial field, whose applications in industrial control will be more and more widely. With the continuous development of PC technology, the traditional man-machine interface will gradually be replaced by the man-machine interface as touch screen and so on. This paper studies structure and function of modular production system (MPS). It emphasizes on how MPS is reformed based on EV touch screen configuration and PROFIBUS-DP Field Bus. S7-300PLC as master communications with S7-200 PLCS through PROFIBUS-DP Field Bus and touch screen communications

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Ma, Panpan, Xiaoying Si, Qiubing Chen, et al. "Oral Drug Delivery Systems for Ulcerative Colitis Therapy: A Comparative Study with Microparticles and Nanoparticles." Current Cancer Drug Targets 19, no. 4 (2019): 304–11. http://dx.doi.org/10.2174/1568009618666181016152042.

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Background: Oral administrations of microparticles (MPs) and nanoparticles (NPs) have been widely employed as therapeutic approaches for the treatment of ulcerative colitis (UC). However, no previous study has comparatively investigated the therapeutic efficacies of MPs and NPs. Methods: In this study, curcumin (CUR)-loaded MPs (CUR-MPs) and CUR-loaded NPs (CUR-NPs) were prepared using a single water-in-oil emulsion solvent evaporation technique. Their therapeutic outcomes against UC were further comparatively studied. Results: The resultant spherical MPs and NPs exhibited slightly negative ze

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Ahmed, Nizam. "Parliament and Poverty Reduction in Bangladesh: Role of the MP." South Asian Survey 25, no. 1-2 (2018): 163–82. http://dx.doi.org/10.1177/0971523119835340.

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This article explores the role of Members of Parliament (MPs) in poverty alleviation in Bangladesh. Under the existing party-dominated parliamentary system, MPs do not have really much to do at the national level; their role is to play second fiddle to their party leaders. What most MPs now do is to try to get involved in different kinds of activities at the local level. The government often remains receptive to demands of the MPs for greater local level involvement for two reasons: first, it can be seen as a strategy to compensate the MPs for their lack of genuine involvement in national poli

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Konkolewska, Magda, Szczepan Kurc, and Ewa Stępień. "A thousand words about microparticles in cardiology." Journal of Medical Science 83, no. 2 (2014): 189–93. http://dx.doi.org/10.20883/medical.e67.

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Microparticles (MPs) are membrane vesicles of 0.1–1 µm in diameter produced mainly by platelets, vascular endothelium and blood cells in response to cell activation and stress factors. MPs can be also released during malignant transformation or apoptosis. The essential step in MP formation is the loss of the cell membrane asymmetric phospholipid distribution as response to the increased intracellular calcium levels. MPs contain, proteins and genetic material (DNA, miRNA, mRNA) which enables them to interact and influence target cell. MPs are considered to be markers of ongoing pathophysiologic

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Lee, Seong-Ho, Hee-Seop Lee, Darshika Amarakoon, and Dmitriy Smolensky. "Effect of Polystyrene Microplastics on Tube Formation and Viability of Endothelial Cells." Current Developments in Nutrition 5, Supplement_2 (2021): 86. http://dx.doi.org/10.1093/cdn/nzab060_004.

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Abstract Objectives Environmental contamination by plastics has become a concern in a wide range of fields; in particular, alarm has risen concerning exposure of human tissues to microplastics (MPs). Despite the fact that MPs cross biological barriers and enter the circulation system, no research has yet explored whether MPs impact the normal function of endothelial cells. The objective is to investigate the adverse vascular events by polystyrene microplastics (PS-MPs), focusing on tube formation and viability, using human umbilical vein endothelial cells (HUVECs). Methods Tube formation (angi

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Rosso, Andrea L., Nicolaas I. Bohnen, Lenore J. Launer, Howard J. Aizenstein, Kristine Yaffe, and Caterina Rosano. "Vascular and dopaminergic contributors to mild parkinsonian signs in older adults." Neurology 90, no. 3 (2017): e223-e229. http://dx.doi.org/10.1212/wnl.0000000000004842.

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ObjectiveMild parkinsonian signs (MPS) are an underappreciated neurologic condition in older adults; we assessed associations of MPS with measures of dopaminergic (catechol-O-methyltransferase [COMT] genotype, an indicator of synaptic dopamine levels) and vascular (white matter hyperintensities [WMH], an indicator of cerebral small vessel disease) factors.MethodsIn a cohort of older adults (mean age 82.6 years [SD 2.6]; 58.0% female; 38.8% black), we assessed cross-sectional associations of WMH volume and COMT Val158Met (rs4680) genotype (n = 35 Met/Met, n = 180 Val carriers) with MPS by regre

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Malafaia, G., T. M. da Luz, A. T. B. Guimarães, and A. P. C. Araújo. "Polyethylene microplastics are ingested and induce biochemical changes in Culex quinquefasciatus (Diptera: Culicidae) freshwater insect larvae." ECOTOXICOLOGY AND ENVIRONMENTAL CONTAMINATION 15 (December 27, 2020): 79–89. http://dx.doi.org/10.5132/eec.2020.01.10.

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Although microplastics’ (MPs) toxicity has been reported in several aquatic and terrestrial organisms, the knowledge about how these pollutants can affect insects at the early developmental stage remains incipient. Thus, the aim of this study was to use Culex quinquefasciatus larvae as a model system to test the hypothesis that, besides accumulating in animals, polyethylene microplastics (PE MPs) lead to biochemical changes predictive of nutritional impacts, as well as induce oxidative stress, redox state imbalance, and neurotoxicity in them. Our results have indicated that short exposure to P

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Słomka, Artur, Aleksandra Piekuś, Mariusz Kowalewski, Wojciech Pawliszak, Lech Anisimowicz, and Ewa Żekanowska. "Assessment of the Procoagulant Activity of Microparticles and the Protein Z System in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery." Angiology 69, no. 4 (2017): 347–57. http://dx.doi.org/10.1177/0003319717706616.

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To understand the coagulation changes after off-pump coronary artery bypass (OPCAB) surgery, we evaluated the procoagulant activity of microparticles (MPs) and microparticles exposing tissue factor (MPs-TF), together with the levels of total tissue factor (TF), protein Z (PZ), protein Z-dependent protease inhibitor (ZPI), and factor X (FX) before (first day) and 1 week after surgery (seventh day) in plasma samples from 30 patients. Twenty healthy controls were also included. Compared to the controls, patients scheduled for surgery had significantly higher MPs-TF procoagulant activity and lower

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Ohashi, Toya, Takashi Yokoo, Sayoko Iizuka, Hiroshi Kobayashi, William S. Sly, and Yoshikatsu Eto. "Reduction of lysosomal storage in murine mucopolysaccharidosis type VII by transplantation of normal and genetically modified macrophages." Blood 95, no. 11 (2000): 3631–33. http://dx.doi.org/10.1182/blood.v95.11.3631.

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Abstract This study examined the ability of macrophages to serve as target cells of gene therapy for mucopolysaccharidosis (MPS) type VII using a murine model. Bone marrow cells were harvested from syngeneic normal mice and differentiated to macrophages. These cells were given to nonmyeloablated MPS VII mice. After transplantation, donor cells populated the liver and spleen. The pathologic improvement at day 38 after transplantation was significant and glycosaminoglycan storage was reduced. To develop gene therapy using this system, a retroviral vector expressing human β-glucuronidase (HBG) wa

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Ohashi, Toya, Takashi Yokoo, Sayoko Iizuka, Hiroshi Kobayashi, William S. Sly, and Yoshikatsu Eto. "Reduction of lysosomal storage in murine mucopolysaccharidosis type VII by transplantation of normal and genetically modified macrophages." Blood 95, no. 11 (2000): 3631–33. http://dx.doi.org/10.1182/blood.v95.11.3631.011k13_3631_3633.

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This study examined the ability of macrophages to serve as target cells of gene therapy for mucopolysaccharidosis (MPS) type VII using a murine model. Bone marrow cells were harvested from syngeneic normal mice and differentiated to macrophages. These cells were given to nonmyeloablated MPS VII mice. After transplantation, donor cells populated the liver and spleen. The pathologic improvement at day 38 after transplantation was significant and glycosaminoglycan storage was reduced. To develop gene therapy using this system, a retroviral vector expressing human β-glucuronidase (HBG) was used to

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Link, Bianca, Louise Lapagesse de Camargo Pinto, Roberto Giugliani, et al. "Orthopedic manifestations in patients with mucopolysaccharidosis type II (Hunter syndrome) enrolled in the Hunter Outcome Survey." Orthopedic Reviews 2, no. 2 (2010): 16. http://dx.doi.org/10.4081/or.2010.e16.

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Mucopolysaccharidosis type II (MPS II or Hunter syndrome) is a rare, inherited disorder caused by deficiency of the lysosomal enzyme iduronate-2-sulfatase. As a result of this deficiency, glycosaminoglycans accumulate in lysosomes in many tissues, leading to progressive multisystemic disease. The cardiopulmonary and neurological problems associated with MPS II have received considerable attention. Orthopedic manifestations are common but not as well characterized. This study aimed to characterize the prevalence and severity of orthopedic manifestations of MPS II and to determine the relationsh

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Wu, Sihui, Yi Tao, Hongliang Zhang, and Zhengquan Su. "Preparation and Characterization of Water-Soluble Chitosan Microparticles Loaded with Insulin Using the Polyelectrolyte Complexation Method." Journal of Nanomaterials 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/404523.

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Polymeric delivery systems based on microparticles have emerged as a promising approach for peroral insulin delivery. The amount of insulin was quantified by the improved Bradford method. It was shown that water-soluble chitosan/insulin/tripolyphosphate (TPP) mass ratio played an important role in microparticles formation. Stable, uniform, and spherical water-soluble chitosan microparticles (WSC-MPs) with high insulin association efficiency were formed at or close to optimized WSC/insulin/TPP mass ratio. WSC-MPs had higher association efficiency in the pH 4.0 and pH 9.7 of TPP solution. The re

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Miyamoto, Ai, Hideyuki Negishi, Akira Endo, et al. "Electrophoretic Deposition Mechanism of Mesoporous Silica Powder in Acetone." Key Engineering Materials 412 (June 2009): 131–36. http://dx.doi.org/10.4028/www.scientific.net/kem.412.131.

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The preparation of a thick coating of mesoporous silica (MPS) on metal substrates by electrophoretic deposition (EPD) has been studied for application to an advanced desiccant cooling system. In this study, we investigated the EPD mechanism of MPS in acetone under a constant applied voltage for the fabrication of a thick MPS coating. We consider that the main contributors to the resistance between the deposition electrode and the counter electrode are the deposited MPS layer and the EPD bath. The current density was measured during EPD under a constant applied DC voltage. The current density d

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Kao, Chen-Yuan, and Eleftherios T. Papoutsakis. "Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and progenitor cells." Science Advances 4, no. 11 (2018): eaau6762. http://dx.doi.org/10.1126/sciadv.aau6762.

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Hematopoietic stem and progenitor cells (HSPCs) are important target cells for gene therapy applications. Current genetic modifications of HSPCs rely on viral vectors in vivo or electroporation ex vivo. Here, we developed a nonviral system based on megakaryocytic microparticles (MPs) for targeted delivery of plasmid DNA (pDNA) and small RNAs to HSPCs. We have previously shown that megakaryocytic MPs, the most abundant MPs in blood circulation, target specifically and deliver cargo to HSPCs both in vitro and in vivo. With an optimized electroporation protocol, an average of 4200 plasmid copies

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Ramesha, Supriya, Sruti Rayaprolu, Christine A. Bowen, et al. "Unique molecular characteristics and microglial origin of Kv1.3 channel–positive brain myeloid cells in Alzheimer’s disease." Proceedings of the National Academy of Sciences 118, no. 11 (2021): e2013545118. http://dx.doi.org/10.1073/pnas.2013545118.

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Kv1.3 potassium channels, expressed by proinflammatory central nervous system mononuclear phagocytes (CNS-MPs), are promising therapeutic targets for modulating neuroinflammation in Alzheimer’s disease (AD). The molecular characteristics of Kv1.3-high CNS-MPs and their cellular origin from microglia or CNS-infiltrating monocytes are unclear. While Kv1.3 blockade reduces amyloid beta (Aβ) burden in mouse models, the downstream immune effects on molecular profiles of CNS-MPs remain unknown. We show that functional Kv1.3 channels are selectively expressed by a subset of CD11b+CD45+ CNS-MPs acutel

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Yoon, Jong-Seo, Jiwon Park, Hye-Rin Ahn, Seong-Jae Yoo, and Yong-Jun Kim. "Microfluidic Airborne Metal Particle Sensor Using Oil Microcirculation for Real-Time and Continuous Monitoring of Metal Particle Emission." Micromachines 12, no. 7 (2021): 825. http://dx.doi.org/10.3390/mi12070825.

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Airborne metal particles (MPs; particle size > 10 μm) in workplaces result in a loss in production yield if not detected in time. The demand for compact and cost-efficient MP sensors to monitor airborne MP generation is increasing. However, contemporary instruments and laboratory-grade sensors exhibit certain limitations in real-time and on-site monitoring of airborne MPs. This paper presents a microfluidic MP detection chip to address these limitations. By combining the proposed system with microcirculation-based particle-to-liquid collection and a capacitive sensing method, the continuous

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O'Dowd, A. "MPs condemn UK clinical trials system for its "invisible" results." BMJ 347, sep17 2 (2013): f5641. http://dx.doi.org/10.1136/bmj.f5641.

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Vera, Moin, Steven Le, Shih-hsin Kan, Patricia Dickson, and Raymond Y. Wang. "Innate immune system activation in MPS I canine vascular disease." Molecular Genetics and Metabolism 111, no. 2 (2014): S109—S110. http://dx.doi.org/10.1016/j.ymgme.2013.12.272.

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O'Dowd, A. "Peer review system must be overhauled and improved, say MPs." BMJ 343, jul28 3 (2011): d4851. http://dx.doi.org/10.1136/bmj.d4851.

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Vagas, Marek, Alena Galajdová, and Martin Džongov. "PROPOSAL OF A VISION SYSTEM FOR AUTOMATED LINE MPS 500." TECHNICAL SCIENCES AND TECHNOLOGIES, no. 4(18) (2019): 108–13. http://dx.doi.org/10.25140/2411-5363-2019-4(18)-108-113.

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Urgency of the research. Research needs from this area are based on designing of effective and affordable vision system solution with aim of automation level increasing in content industry 4.0 and should be an advantageous solution mainly for SMEs. In overall, development direction in vision system area pointed to the necessity for innovative technologies implementation that starts from supply chains up to customers. Target setting. Main aim of article is to propose a solution for image processing of selected assembly parts at specified automated line from FESTO company to automate monitoring

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